assoc_id	FEATURE	Drug id	Drug name	Drug Target	N_FEATURE_pos	N_FEATURE_neg	log max.Conc.tested	log max.Conc.tested2	FEATUREpos_logIC50_MEAN	FEATUREneg_logIC50_MEAN	FEATURE_deltaMEAN_IC50	FEATUREpos_IC50_sd	FEATUREneg_IC50_sd	FEATURE_IC50_effect_size	FEATUREpos_Glass_delta	FEATUREneg_Glass_delta	FEATURE_ANOVA_pval	Tissue_ANOVA_pval	MEDIA_ANOVA_pval	MSI_ANOVA_pval	FEATURE_IC50_T_pval	ANOVA FEATURE FDR %
a1	loss_cnaOV102	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	4.80925422298397	1.04471468962487	3.7645395333591	1.00576388628559	0.923847629630363	4.04907286728709	3.74296550581273	4.07484893895903	5.38365557909232e-07	NA	NA	0.267522992995546	0.0161339234107684	0.510817002869484
a2	loss_cnaOV102	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	1.27770054095358	-0.942201715487893	2.21990225644147	0.230564747514744	0.678007456303346	3.37175708156088	9.62810785417018	3.27415611112139	4.71794700676984e-06	NA	NA	0.00524242307172486	8.82593271490401e-06	2.12966412987966
a3	PIK3CA_mut	326	GSK690693	AKT	6	26	2.32630161961136	NA	1.97257984157374	4.65485837344411	-2.68227853187037	1.70530515512543	0.780027603977927	2.69346143386695	1.57290237691979	3.4386969360975	6.73355317658576e-06	NA	NA	0.0202060606243145	0.0110299937542441	2.12966412987966
a4	TP53_mut	1047	Nutlin-3a	MDM2	23	10	2.07944154167984	1.38629436111989	4.39141976429843	2.26714624197478	2.12427352232365	1.13310307536913	1.37520999074846	1.75792302053947	1.87473987892197	1.54469029211133	1.30803558815185e-05	NA	NA	0.0605321487460506	0.000682383276207186	3.10275615225651
a5	loss_cnaOV43_(NF1)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	5	26	2.30258509299405	NA	3.71376816903077	0.965805120511326	2.74796304851945	1.67111298747237	0.908430384117409	2.62412957252661	1.64439093533457	3.0249572191371	1.67708803299177e-05	NA	NA	0.324096314623042	0.0192992711163992	3.18254045035166
a6	PIK3R1_mut	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	1.06276692911507	3.31405746841471	-2.25129053929963	0.842414081924251	0.923145360296874	2.46009294335129	2.67242747670743	2.43871727695803	0.000393215185356477	NA	NA	0.0360400816283766	0.00719841986812224	38.7240797073157
a7	loss_cnaOV102	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.86770487038902	1.48482968139499	1.38287518899403	0.564852456680153	0.548318375256699	2.51689890912813	2.44820602732561	2.5220296298599	0.000432032955692232	NA	NA	0.123532090307521	0.0406446862976686	38.7240797073157
a8	PIK3R1_mut	308	XL-880	MET	5	27	1.63315443905142	NA	1.5858173711106	0.00629859137469351	1.5795187797359	1.77928078413282	0.463012805667977	2.02584210675301	0.887728791218147	3.41139329279926	0.000446863653033461	NA	NA	0.268907330413263	0.118058078785592	38.7240797073157
a9	loss_cnaOV44	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	4.0558823222738	1.1254331075581	2.9304492147157	2.09953049860275	1.07811331278965	2.48900632085623	1.3957640609012	2.71812728769026	0.000485983057460534	NA	NA	0.378736772447831	0.133118194510795	38.7240797073157
a10	PIK3R1_mut	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-1.22597169419891	-4.73619482197083	3.51022312777193	3.87961325326977	1.37424486113393	1.80810723708967	0.904786868849228	2.55429234414276	0.000514748750489163	NA	NA	0.910358303938465	0.112940895666158	38.7240797073157
a11	PIK3CA_mut	282	EKB-569	EGFR	6	26	0.916290731874155	2.99573227355399	-0.0697610690225824	2.0882319198403	-2.15799298886289	1.58117662919725	1.13083697288261	1.77245459458812	1.36480197658783	1.90831485051462	0.000543541911763892	NA	NA	0.231075312567195	0.0185474141504491	38.7240797073157
a12	TP53_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	21	10	0.693147180559945	NA	0.412096187324654	-1.35451190510543	1.76660809243009	1.33308485268094	1.47661652804251	1.28086680746052	1.32520303480855	1.19638921743075	0.00055258881760615	NA	NA	0.0453159570267551	0.00536560418309677	38.7240797073157
a13	PIK3R1_mut	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-4.58650670640889	-1.65052109603661	-2.93598561037228	1.16281424182447	1.20492462745876	2.44535685531187	2.52489650089397	2.43665499356952	0.000568699443984066	NA	NA	0.0119953272472643	0.00926942187359301	38.7240797073157
a14	loss_cnaOV87, loss_cnaOV88	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	0.915065969780517	-0.905938258370587	1.8210042281511	0.838622449994551	0.752627383242347	2.4008924019925	2.17142318115015	2.41952959551664	0.000571374776537502	NA	NA	0.0149450251830753	0.054233890671655	38.7240797073157
a15	loss_cnaOV102	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	5.5819857626352	1.67568748379141	3.90629827884378	1.97599668785032	1.59466124553517	2.40702543664225	1.97687491222136	2.449610091034	0.000629641998205193	NA	NA	0.0690587144685377	0.0671001984346111	39.8281841125452
a16	PIK3R1_mut	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	4.62474764185854	2.97135717078531	1.65339047107324	0.532315200473196	1.1359035813937	1.5377740059366	3.10603655428865	1.45557290086594	0.000717076426187861	NA	NA	0.525739736043886	0.000239025919630552	42.5239441714296
a17	loss_cnaOV34	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	3.46237825655919	4.61059131115848	-1.14821305459929	0.402051851856168	0.632275821764363	1.89271544945686	2.85588301433831	1.81600025665256	0.00079170033281556	NA	NA	0.441641400687748	0.000671113189902617	44.1875561227752
a18	loss_cnaOV43_(NF1)	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	0.496483574177387	-0.961263132595107	1.45774670677249	1.22423694064971	0.6629639644142	1.92042208293284	1.19073902965128	2.19883249319678	0.00084004227378906	NA	NA	0.0160807137641334	0.0545686640446984	44.2809279428662
a19	PIK3R1_mut	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	0.948826222039933	2.76781084265506	-1.81898462061513	0.714226622700662	0.842255330137097	2.19291182145389	2.54678916019276	2.15965937587957	0.00102416832184277	NA	NA	0.117965510822213	0.00785203941978734	48.9222655333102
a20	loss_cnaOV34	290	KIN001-260	IKK	5	26	2.99573227355399	NA	3.75646264576282	5.06058945493357	-1.30412680917075	0.819830583404319	0.752863893884519	1.71044140043629	1.59072720092413	1.73222121523441	0.00103121323801172	NA	NA	0.601559068215977	0.0192778838930625	48.9222655333102
a21	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	302	PI-103	PI3Ka, PRKDC (DNAPK)	7	25	2.32630161961136	NA	3.62597070643827	0.635791073038174	2.9901796334001	1.44757710966972	2.07873016937327	1.51881853490742	2.06564445750482	1.43846453832997	0.0011346356006615	NA	NA	0.278372474259157	0.000688074305044384	51.2128519205532
a22	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	346	THZ-2-102-1	CDK7	7	25	0.916290731874155	2.99573227355399	0.953243091239993	-1.62296338555111	2.5762064767911	1.77027037703367	1.62854765722921	1.55393328376729	1.45526158614702	1.58190426012723	0.0012039816411415	NA	NA	0.361270692876565	0.0070763555102649	51.2128519205532
a23	SMAD4_mut	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	4.7552999214102	3.39653792726584	1.35876199414435	1.24235948082665	0.741172081365029	1.69114703901403	1.09369471164679	1.83326116607347	0.00130042417316753	NA	NA	0.0849395627397901	0.114098570280042	51.2128519205532
a24	loss_cnaOV87, loss_cnaOV88	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	3.88996164062971	1.14321032344854	2.74675131718117	2.36931349983586	1.08521244148495	2.25506377777076	1.15930260700893	2.53107245381619	0.00132026324163791	NA	NA	0.394511637278454	0.179887247156444	51.2128519205532
a25	loss_cnaOV35	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	3.69453109369099	4.54148697367537	-0.846955879984381	0.682303337850753	0.529620007164204	1.53316989499146	1.2413186818817	1.59917652000973	0.00134936951204892	NA	NA	0.192348236661801	0.0470034316375848	51.2128519205532
a26	gain_cnaOV96	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	5.95066975995962	3.7586927761636	2.19197698379602	0.630641957429044	1.36611104673344	1.6716562454024	3.47578678832615	1.60453792467116	0.00167404467083388	NA	NA	0.25103077774586	0.000670419083343624	56.2765115756637
a27	PIK3R1_mut	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	2.19863280985338	4.23200752510116	-2.03337471524778	1.17953378757113	0.911790487095346	2.15623734891816	1.72388000807918	2.23008985509974	0.00173055995523814	NA	NA	0.0415828483163625	0.0355671162988962	56.2765115756637
a28	PIK3R1_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	2.83085714471654	0.665903785943909	2.16495335877263	0.57435212897459	1.41566759028088	1.62229859478826	3.76938336180244	1.52928086624	0.00178301394530613	NA	NA	0.754735545376483	3.50774268139301e-05	56.2765115756637
a29	loss_cnaOV16, loss_cnaOV17	1149	TW 37	BCL2, BCL2L1	6	27	1.6094379124341	NA	0.322180299413365	-0.976519690305787	1.29869998971915	1.15977428809242	0.675738789355279	1.67672366197782	1.11978684391705	1.92189646380703	0.00186809580461682	NA	NA	0.0186246261373167	0.0396976214962429	56.2765115756637
a30	PIK3CA_mut	1010	Gefitinib	EGFR	6	24	-0.693147180559945	NA	-0.240320302879418	1.21686258218286	-1.45718288506228	1.23563114852424	1.1054272471617	1.2897946034883	1.1793024858613	1.31820785927229	0.00187010286600517	NA	NA	0.949322751133739	0.0329877572676307	56.2765115756637
a31	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	3.82703145172468	1.14995284368837	2.67707860803631	2.47267399603501	1.0856053206523	2.17216674567488	1.08266541093936	2.46597778871215	0.00187026547791037	NA	NA	0.399937720722966	0.199471030826142	56.2765115756637
a32	KRAS_mut	1017	Olaparib	PARP1, PARP2	7	24	1.6094379124341	NA	2.7784764382447	4.31705830622633	-1.53858186798163	1.34381319454381	0.847756143073435	1.58388191494562	1.14493731288592	1.81488731229206	0.00189796880723541	NA	NA	0.0421690946581366	0.0225401469327848	56.2765115756637
a33	loss_cnaOV43_(NF1)	164	JQ12	HDAC	3	16	1.63315443905142	NA	4.97600758805333	1.19724658298027	3.77876100507306	0.273897664024395	1.8144959718998	2.21367332009448	13.7962513062415	2.08254031069391	0.00202720567711824	NA	NA	0.556061446008931	4.61678943347245e-07	57.9318417227315
a34	loss_cnaOV59	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	4.86440172556918	3.38148940255426	1.48291232301492	1.09975995697123	0.735411393323718	1.90565840926454	1.34839636014653	2.01643914749926	0.00210820727499642	NA	NA	0.0894694259715071	0.0700180241071966	57.9318417227315
a35	loss_cnaOV83	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-2.527223927472	-4.49015223288342	1.96292830541142	1.87408840472737	0.968838338704941	1.73378869100421	1.04740432759733	2.02606381993026	0.0022226962518486	NA	NA	0.150943292889886	0.0781303923431451	57.9318417227315
a36	loss_cnaOV102	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-1.67008375211485	-4.31581105551695	2.6457273034021	0.668734440383324	1.34288631656473	2.02334656116113	3.95631979397614	1.97017965762746	0.00224097932051363	NA	NA	0.840316351940291	0.00444753668117373	57.9318417227315
a37	loss_cnaOV87, loss_cnaOV88	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	4.94056592987844	3.33591163331392	1.60465429656452	0.201984212942302	0.803160836061371	2.06117906859168	7.94445404019224	1.99792398298901	0.0022590767344059	NA	NA	0.761467875177518	2.7127576188845e-06	57.9318417227315
a38	loss_cnaOV16, loss_cnaOV17	1072	BMS-708163	g-secretase	6	27	1.6094379124341	NA	4.73890871180142	3.64192445474586	1.09698425705556	0.629390509236714	0.776262901322398	1.45390275344063	1.74293104353593	1.41316074127309	0.00257951863210946	NA	NA	0.911653154987623	0.00522989671116554	63.1642102459344
a39	loss_cnaOV102	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.03086130012032	-4.40612572499487	2.37526442487455	2.43829839122447	0.99066033197922	2.07343191383698	0.974148378813366	2.39765775230856	0.00276199251019784	NA	NA	0.153699556383305	0.232148375241818	63.1642102459344
a40	loss_cnaOV35	290	KIN001-260	IKK	5	26	2.99573227355399	NA	3.84033576450716	5.0444600090212	-1.20412424451405	0.963340985288704	0.753614240481103	1.53220502100866	1.24994603458419	1.59779921853035	0.00279861006618181	NA	NA	0.613478077993037	0.0458993446937519	63.1642102459344
a41	loss_cnaOV40	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	-1.45777303248496	0.577696095550462	-2.03546912803542	0.638167377803216	1.515324238261	1.47459427307774	3.18955371088097	1.34325649695364	0.00288579248694223	NA	NA	0.391230800102994	2.39454928940923e-05	63.1642102459344
a42	SMAD4_mut	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	5.72727973074142	4.26476118341153	1.46251854732989	0.509413019514111	0.92232192836636	1.6418629672351	2.87098776691037	1.58569204780844	0.00289039069060918	NA	NA	0.306462107335294	0.00285955625196768	63.1642102459344
a43	gain_cnaOV72_(ASXL1)	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	3.71450466959781	2.32678386972961	1.38772079986821	0.559495618436282	0.94957341308762	1.52715086658347	2.48030682303948	1.46141496880785	0.00301865636346531	NA	NA	0.32758468987428	0.00154813412121604	63.1642102459344
a44	loss_cnaOV102	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	2.81410126761613	0.668061414293393	2.14603985332273	1.80536040500978	1.00591690546366	1.99109011715434	1.18870439795156	2.13341662881542	0.00307333751643112	NA	NA	0.820686108059267	0.172071144677321	63.1642102459344
a45	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	7.0418121253643	4.33296562054545	2.70884650481885	0.586156931073157	1.26021337849672	2.25602577227518	4.6213673526975	2.14951416247474	0.00317391418351293	NA	NA	0.0482338665814187	0.000899885621609451	63.1642102459344
a46	BRCA1_mut	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	3.73184497983176	2.21983477584797	1.51201020398379	0.278152677944365	0.773415793037352	2.01431015866307	5.43590022270507	1.95497715148256	0.0032217604815833	NA	NA	0.553104586411794	0.000362412478595481	63.1642102459344
a47	SMAD4_mut	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	4.65632457884956	3.31978443012602	1.33654014872354	0.591390399729203	0.812460159297512	1.68380514341677	2.25999635661239	1.64505315544232	0.00347079109740105	NA	NA	0.764516450270742	0.0112603278594645	63.1642102459344
a48	KRAS_mut	1020	Lenalidomide	TNFA	7	24	1.6094379124341	NA	3.64826294081746	4.61915959659357	-0.970896655776107	0.825933390326857	0.603260382563212	1.48100578281644	1.17551447507393	1.60941557549467	0.00349203615221827	NA	NA	0.0204131154555384	0.0202022305036533	63.1642102459344
a49	loss_cnaOV41	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	3.36740265840587	1.11889493869722	2.24850771970865	2.1987957006691	1.09808482378382	1.78814061357785	1.0226087485183	2.04766305025568	0.00350288630378536	NA	NA	0.409607158958161	0.131774396461693	63.1642102459344
a50	loss_cnaOV42	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	3.36740265840587	1.11889493869722	2.24850771970865	2.1987957006691	1.09808482378382	1.78814061357785	1.0226087485183	2.04766305025568	0.00350288630378536	NA	NA	0.409607158958161	0.131774396461693	63.1642102459344
a51	loss_cnaOV33_(ZFHX3)	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	3.4498975699487	4.57136665729572	-1.12146908734702	0.463129721049626	0.654252531613066	1.75855198963886	2.4215010101389	1.71412265625022	0.00362386454609076	NA	NA	0.463576781952715	0.00824974501172735	63.1642102459344
a52	gain_cnaOV18_(CCNE1)	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	2.67062147027974	0.591905521473127	2.07871594880661	1.36994073679137	1.13743993618713	1.78895068658339	1.51737654993406	1.8275390925474	0.00368134591053626	NA	NA	0.111762164736115	0.0502122015069665	63.1642102459344
a53	loss_cnaOV87, loss_cnaOV88	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.08432759402174	-4.40059472907404	2.3162671350523	2.49260873875911	0.99456269769167	2.00288072641414	0.929254198236264	2.32893023278295	0.00371323818391542	NA	NA	0.157472667725859	0.247531081375131	63.1642102459344
a54	KRAS_mut	1033	Vismodegib	SMO	7	24	2.30258509299405	NA	4.08093223248769	5.15302989215755	-1.07209765966986	0.799998058022811	0.714783117257347	1.46216379012444	1.34012532770335	1.499892252329	0.00378298614704309	NA	NA	0.101323115264762	0.0109602802120349	63.1642102459344
a55	loss_cnaOV87, loss_cnaOV88	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	5.14996844375198	3.71051690725636	1.43945153649562	0.629505752056894	0.768155032839854	1.89408089941125	2.28663762291647	1.8739075771905	0.00383396528862763	NA	NA	0.91272283813708	0.0426605724885962	63.1642102459344
a56	PIK3CA_mut	283	GSK2126458	PI3K, MTOR	6	26	-2.05572501506252	0.0237165266173161	-4.38969764292402	-2.34967957903972	-2.0400180638843	1.67046235815709	1.56414350947077	1.28922542185655	1.22122959186875	1.30423970149295	0.00383580476168815	NA	NA	0.653477471092289	0.0287484867172322	63.1642102459344
a57	SMAD4_mut	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.10343630087059	-4.39861796629657	2.29518166542598	2.50441599961214	0.997186989747249	1.97814205865199	0.916453842245633	2.30165624805006	0.00411564967410922	NA	NA	0.158788805985601	0.252142324490668	63.1642102459344
a58	PIK3R1_mut	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	5.27734106354481	4.27448708764263	1.00285397590218	0.497399309008245	0.661296967733279	1.56240261971695	2.01619495190244	1.51649565147661	0.00421447867583794	NA	NA	0.465703444609067	0.00591094113569526	63.1642102459344
a59	loss_cnaOV43_(NF1)	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	0.303609446686293	-1.92399875101193	2.22760819769822	1.33350244350344	0.965382624804795	2.19330532451047	1.6704942750954	2.30748735316078	0.00428593401216901	NA	NA	0.527274908691338	0.0895930506358036	63.1642102459344
a60	loss_cnaOV20	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.97400331745156	3.58376264579724	1.39024067165432	0.614476141143877	0.935702177855443	1.54552851866724	2.26248112590071	1.48577261500091	0.00433739723243549	NA	NA	0.678163531657232	0.00291366245863193	63.1642102459344
a61	TP53_mut	1019	Bosutinib	SRC, ABL, TEC	21	10	0.693147180559945	NA	2.17852316548005	0.767937432837501	1.41058573264255	1.37201231074814	1.64249582682565	0.96527986168141	1.02811448672306	0.858806281029463	0.0044077737855682	NA	NA	0.0201789058265524	0.032478205289499	63.1642102459344
a62	loss_cnaOV38	266	Zibotentan, ZD4054	Endothelin A Receptor	8	24	2.99573227355399	NA	5.35741458305202	5.83429302736639	-0.476878444314369	0.498229851357784	0.409936108523217	1.10349057376891	0.957145468130368	1.16329943715451	0.00452818169163802	NA	NA	0.317761561932884	0.0337671924525624	63.1642102459344
a63	loss_cnaOV43_(NF1)	1248	FK866	NAMPT	5	27	0	NA	1.5512461881057	-2.31198810800451	3.86323429611022	1.32661263410083	2.49562973647908	1.62781237529572	2.91210425470483	1.54799978524082	0.0045829215235227	NA	NA	0.0229293429126972	0.000450740569108333	63.1642102459344
a64	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	3.63976693155297	1.50928161939303	2.13048531215993	2.40520959901182	1.51468738647059	1.20832296309578	0.885779481769591	1.40655116771272	0.00469463997738344	NA	NA	0.0872821951920764	0.0432057751990955	63.1642102459344
a65	ARID1A_mut	1005	Cisplatin	DNA crosslinker	9	22	1.79175946922805	2.30258509299405	2.00262516024148	3.44122695097655	-1.43860179073507	1.1697849202284	0.920085400287998	1.4454748129679	1.22980025289964	1.56355245967904	0.0048618230849336	NA	NA	0.05253731430494	0.00622111783526803	63.1642102459344
a66	PIK3CA_mut	1032	Afatinib	ERBB2, EGFR	7	24	-0.693147180559945	NA	-0.918154904063768	0.729043960478238	-1.64719886454201	1.64831635324006	1.50073234251383	1.07489089294939	0.999322042339833	1.09759669854441	0.00501255338920637	NA	NA	0.813829691463146	0.0413996863977965	63.1642102459344
a67	loss_cnaOV56	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	3.54260909735387	4.49879229191822	-0.956183194564351	0.564382708084303	0.568788338953667	1.68195328004036	1.69421064973791	1.68108790050677	0.00512893092805523	NA	NA	0.211087162555322	0.0864203990040793	63.1642102459344
a68	loss_cnaOV102	1262	UNC1215	LMBL3	3	30	0	NA	3.53972439622498	2.70448153537098	0.835242860854003	0.428920639033879	0.433206874413095	1.92927200316386	1.94731329025188	1.9280461834443	0.00513279128964281	NA	NA	0.0711607788987232	0.0654588016214168	63.1642102459344
a69	loss_cnaOV87, loss_cnaOV88	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.5602856626263	0.544629344004771	1.01565631862153	0.491070280120677	0.545503925250042	1.87374870656628	2.06825043122531	1.86186802992477	0.00514533706394167	NA	NA	0.00631282856359496	0.0553688201539401	63.1642102459344
a70	loss_cnaOV43_(NF1)	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.91913491762576	2.65896039665952	1.26017452096624	1.13377309366978	0.945283736396002	1.2957710714047	1.111487411372	1.33311774279625	0.00524192754299892	NA	NA	0.245614086467888	0.0655902517282495	63.1642102459344
a71	loss_cnaOV57_(ZNRF3)	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	4.29266110699978	0.86092597653654	3.43173513046324	1.48876982625297	2.08440998454103	1.68825162107423	2.30508106085173	1.64638202460869	0.00541791333555711	NA	NA	0.302072293434943	0.0101157436544921	63.1642102459344
a72	gain_cnaOV26	308	XL-880	MET	3	29	1.63315443905142	NA	1.59622952482731	0.114153801661648	1.48207572316566	2.58529474895017	0.580122277252594	1.7004054010609	0.573271470793611	2.55476436827187	0.00555071621903748	NA	NA	0.307273777620165	0.425454354742763	63.1642102459344
a73	loss_cnaOV87, loss_cnaOV88	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	5.28941718420845	4.3652979061174	0.924119278091057	0.328960657519289	0.496593484602462	1.89673561612918	2.80920911655483	1.86091704129152	0.0055832897577966	NA	NA	0.303907811461767	0.0214429015979723	63.1642102459344
a74	SMAD4_mut	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	2.40399657543945	1.50168532392371	0.90231125151574	0.652146068309003	0.612527349165174	1.46335665397067	1.38360299227964	1.47309545075092	0.0056939844151969	NA	NA	0.155118618790912	0.0627666304487021	63.1642102459344
a75	gain_cnaOV72_(ASXL1)	1030	KU-55933	ATM	5	28	2.30258509299405	NA	5.26288274700615	3.9524433157958	1.31043943121035	0.506648222008231	0.964235255045222	1.42734189970112	2.58648777255367	1.3590453412211	0.0057270823838791	NA	NA	0.477562443858201	0.0010723469174714	63.1642102459344
a76	loss_cnaOV52, loss_cnaOV53	286	KIN001-236	TIE2	8	24	2.32630161961136	NA	5.33908669359931	4.61373203346423	0.725354660135083	0.366137698248517	0.637935961922085	1.23800786916959	1.9810979956583	1.13703365765681	0.00574218625735574	NA	NA	0.730999464756856	0.000699906342075109	63.1642102459344
a77	loss_cnaOV38	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	0.693147180559945	4.05966292722577	2.42296291860265	1.63670000862311	0.952110788364131	1.50159946623661	1.17196026603093	1.71902264802104	1.08997109110933	0.00593930732917937	NA	NA	0.964764248617166	0.00178323345059516	63.1642102459344
a78	loss_cnaOV34	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	4.4229810696918	5.33298792337781	-0.910006853686013	0.586338576355528	0.714577837173264	1.30216722638541	1.55201600301022	1.27348877385538	0.00605146652259764	NA	NA	0.273983681043843	0.0200111548992161	63.1642102459344
a79	PTEN_mut	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	4.56164891113337	3.09191155472744	1.46973735640593	0.468569919637939	1.19375566294869	1.26744536883439	3.13664470297536	1.23118775644217	0.00605351586049531	NA	NA	0.553337634396839	0.00711967138214241	63.1642102459344
a80	gain_cnaOV18_(CCNE1)	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	3.68594395571827	0.540185970871365	3.14575798484691	1.98242627447177	1.84229822786781	1.69796932973317	1.58682218116037	1.70751832535151	0.00608059040244872	NA	NA	0.352716981014589	0.0991303714590292	63.1642102459344
a81	loss_cnaOV102	1030	KU-55933	ATM	3	30	2.30258509299405	NA	5.67714764390019	3.99837945485375	1.67876818904643	0.493209883326061	0.932971452910735	1.84271798163007	3.4037602363629	1.79937787357686	0.00643477188490762	NA	NA	0.479113126035803	0.00909557037294637	63.1642102459344
a82	loss_cnaOV44	1248	FK866	NAMPT	3	29	0	NA	2.40740848939183	-2.13412667047479	4.54153515986662	0.486052225529531	2.50276169231342	1.87577431052029	9.34371847576428	1.81460950669605	0.00649601163136332	NA	NA	0.0243388889250712	1.17545284994056e-07	63.1642102459344
a83	loss_cnaOV83	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.76157971848188	3.67705406987634	1.08452564860554	0.644181655279264	0.791284027623565	1.40142062696755	1.68357114754437	1.37058958698138	0.00650786468093255	NA	NA	0.914119816500375	0.0142301977560532	63.1642102459344
a84	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	194	AUY922	HSP90	3	16	-1.36257783450257	NA	0.229203653673255	-3.06587823179373	3.29508188546698	2.23304283528603	1.47253507164247	2.08403313221895	1.47560173651793	2.23769331469411	0.00657116626467533	NA	NA	0.240193614168355	0.115134708641057	63.1642102459344
a85	loss_cnaOV87, loss_cnaOV88	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	5.62589888465139	4.27465853263438	1.35124035201701	0.2393622572933	0.793034459334102	1.75615300702346	5.64516882192203	1.70388604948091	0.00658705251817238	NA	NA	0.853227793491135	0.00013488363358418	63.1642102459344
a86	loss_cnaOV56	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	5.30620216951424	3.64527591431864	1.6609262551956	0.317836954058042	0.939718899140284	1.82207756761583	5.22571788456131	1.76747137544549	0.00661793784035591	NA	NA	0.68219193027539	0.000346171310720804	63.1642102459344
a87	gain_cnaOV26	310	YM201636	FYV1	3	29	1.63315443905142	NA	3.57222559092991	2.23119494888377	1.34103064204614	0.877851242145892	0.768316712940514	1.72790934825375	1.52762857493716	1.7454138631369	0.00667418348901134	NA	NA	0.608753672344688	0.108231017295781	63.1642102459344
a88	loss_cnaOV87, loss_cnaOV88	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	2.24013491944734	-0.41469656698495	2.65483148643229	0.681132594670559	1.4437789672279	1.89017737719194	3.8976720644478	1.83880742599378	0.00668393557283354	NA	NA	0.0640181099910694	0.00412301497285326	63.1642102459344
a89	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	6.28468490326994	5.05900314086325	1.22568176240669	0.209781372145217	0.626279781359315	2.06139507324116	5.8426625294368	1.95708339768913	0.00680370154364244	NA	NA	0.0636495374490181	8.38212065521793e-05	63.1642102459344
a90	PIK3R1_mut	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	4.35219332901345	2.63738396842462	1.71480936058883	1.35874710606298	1.03193378252203	1.58597801859928	1.2620518954094	1.66174360180153	0.00696168482039538	NA	NA	0.178280821808362	0.0446833169909219	63.1642102459344
a91	PIK3R1_mut	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	1.90328502106863	-0.22523577075103	2.12852079181966	1.78302742293594	1.35636860627529	1.49596120180809	1.1937678380262	1.56927901602262	0.00714741117046582	NA	NA	0.405125679947346	0.0530693114914396	63.1642102459344
a92	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	0.620413129488956	-0.876472974341431	1.49688610383039	1.34631088091408	0.768817678122078	1.82889400260461	1.11184283292286	1.94699750854676	0.00751965757693882	NA	NA	0.0236679665510097	0.190607964413223	63.1642102459344
a93	loss_cnaOV87, loss_cnaOV88	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	4.12770065216097	2.74171007495126	1.38599057720971	1.10078066650712	0.656340521139092	1.95005475591091	1.25909785607662	2.11169436073259	0.0075745463735306	NA	NA	0.248873339492211	0.154849335647814	63.1642102459344
a94	loss_cnaOV59	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	5.4472398683466	3.88927681597639	1.55796305237021	0.707638867693811	1.02338500016657	1.56371209264152	2.20163578273704	1.52236260265357	0.00758807222759638	NA	NA	0.79740266964833	0.0117861324518552	63.1642102459344
a95	loss_cnaOV16, loss_cnaOV17	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	6	25	2.30258509299405	NA	2.84318174243708	1.06482734095304	1.77835440148404	2.36909974740653	0.915208586533937	1.37990198265276	0.750645642265936	1.94311376406443	0.00761350252871233	NA	NA	0.421348456332495	0.126669669067187	63.1642102459344
a96	ARID1A_mut	1049	PD-173074	FGFR1, FGFR3	9	24	0.693147180559945	NA	2.13649785808572	3.30526443943095	-1.16876658134523	0.820306557846244	0.874058997813746	1.35822717832422	1.42479243907776	1.33717127135425	0.0076550117520224	NA	NA	0.0570530082822278	0.00266334424938377	63.1642102459344
a97	loss_cnaOV42	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.87365679888013	3.69899259839401	1.17466420048612	0.754703580850771	0.779107961650511	1.51222298147986	1.55645770113072	1.50770401318661	0.0077198867014539	NA	NA	0.914562894619854	0.0446686142343349	63.1642102459344
a98	gain_cnaOV72_(ASXL1)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-0.702798792280091	-2.58315741422626	1.88035862194617	1.51986974169949	1.46562720636773	1.27677697875853	1.23718406278922	1.28297196843546	0.00784952754600136	NA	NA	0.0866586972486996	0.0469322957797419	63.1642102459344
a99	SMARCA4_mut	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.04987067706882	5.30882645684322	-1.2589557797744	0.607776034677198	0.683922775393571	1.8538264165526	2.07141398795538	1.84078645290021	0.00789550406937118	NA	NA	0.277923616146502	0.0548924282663011	63.1642102459344
a100	SMAD4_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	5.15735745052504	4.0598415729996	1.09751587752544	1.03853680845865	0.891708573271216	1.20943574136777	1.05679054279677	1.23080108280133	0.00797171505948838	NA	NA	0.0276040216802009	0.121256561508476	63.1642102459344
a101	loss_cnaOV43_(NF1)	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	4.24100990210494	1.63466091879007	2.60634898331487	2.6996399609813	1.55275196339904	1.48963229563825	0.965443177973808	1.67853530038981	0.00809160700408866	NA	NA	0.0925328274063583	0.0964169838899658	63.1642102459344
a102	SMAD4_mut	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	4.93181519276484	1.74294650826076	3.18886868450408	2.82441202454222	1.65719396183534	1.8126104945452	1.12903806413334	1.92425796734886	0.00809941735662799	NA	NA	0.0925422281302599	0.185940280320113	63.1642102459344
a103	loss_cnaOV102	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.86773334857816	4.30506606504739	1.56266728353077	0.625841826306288	0.888811496128642	1.78846866325527	2.49690451779743	1.75815377089204	0.00817184629035514	NA	NA	0.016618755816977	0.0308706022751485	63.1642102459344
a104	loss_cnaOV59	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	2.36039986808671	0.656231619464641	1.70416824862207	1.90953914237515	0.986360033223863	1.53023433778937	0.892450021476058	1.72773448965901	0.0085919309321868	NA	NA	0.82633252643602	0.171460536941211	63.1642102459344
a105	PIK3R1_mut	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	3.78031635569689	5.0784436154225	-1.29812725972561	0.518955286583583	0.763122640742702	1.75043811618196	2.50142409815596	1.70107292120467	0.00859849634338716	NA	NA	0.110273703491353	0.00679363902138441	63.1642102459344
a106	loss_cnaOV16, loss_cnaOV17	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.85509599193479	2.67081945697267	1.18427653496212	1.1408414968012	0.959787304677394	1.2012734570249	1.03807280703122	1.2338947693835	0.00892410385340905	NA	NA	0.253366602527023	0.0797443502220127	63.1642102459344
a107	loss_cnaOV59	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	4.49930549613399	1.69084544047574	2.80846005565825	2.71874637501118	1.61837385873712	1.59603059803779	1.03299817940785	1.73535925614233	0.00893079337268163	NA	NA	0.0934959569276167	0.128615537814365	63.1642102459344
a108	loss_cnaOV43_(NF1)	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	1.40159131273473	-0.92230497621085	2.32389628894558	1.78817633037299	1.11421069576161	1.91567772405118	1.29959011842017	2.08568836916172	0.00895076692901349	NA	NA	0.888287701023754	0.145024430587658	63.1642102459344
a109	SMARCA4_mut	1030	KU-55933	ATM	3	30	2.30258509299405	NA	2.67536716280509	4.29855750296326	-1.62319034015817	0.0421643066674714	0.950972098884996	1.7646317303762	38.4967871749786	1.7068748305669	0.00902282476165257	NA	NA	0.483575666169745	2.68167358076318e-10	63.1642102459344
a110	loss_cnaOV43_(NF1)	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	1.5379744040211	0.0566865154512303	1.48128788856987	0.745304055429441	1.04223668114747	1.4682997357756	1.98749473826002	1.42125864054125	0.00914595803265739	NA	NA	0.107145557714785	0.00623190234771309	63.1642102459344
a111	KRAS_mut	1016	Temsirolimus	MTOR	7	24	-1.6094379124341	NA	-3.42003713486636	-1.62374318643998	-1.79629394842638	1.64630745831057	1.28683798994504	1.31214298586283	1.09110478687239	1.39589751193397	0.00941712570090549	NA	NA	0.020904520018657	0.0280344509120878	63.1642102459344
a112	loss_cnaOV33_(ZFHX3)	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	2.07289540876846	4.15342481300802	-2.08052940423957	1.61401102918551	1.41054014338787	1.45194141235678	1.28904286688145	1.47498773004964	0.00945041073992238	NA	NA	0.682568888120308	0.0758646970306557	63.1642102459344
a113	SMAD4_mut	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	5.21751592517309	4.38934345843716	0.828172466735928	0.619408498744591	0.651447621898962	1.27722348419816	1.33703762285222	1.27128020564695	0.00950201827675825	NA	NA	0.0537045811518607	0.0678129635391119	63.1642102459344
a114	loss_cnaOV58	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	0.841198920799828	-1.41138435570729	2.25258327650712	1.24639179810331	1.87216368359879	1.25050991034418	1.80728345608096	1.20319782732729	0.00951322366542808	NA	NA	0.392283689780574	0.00975007926860744	63.1642102459344
a115	loss_cnaOV87, loss_cnaOV88	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-1.98993135887733	-4.28154166907811	2.29161031020078	0.951751753123619	1.3945743325299	1.67436748968964	2.40778154879125	1.64323281789043	0.00956620988226785	NA	NA	0.847658033455097	0.0326178395783879	63.1642102459344
a116	PIK3R1_mut	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	4.47769819980775	3.37153461212459	1.10616358768316	1.2840652922609	0.711798680404505	1.36268155813661	0.861454315719022	1.55403995277786	0.0096071928437597	NA	NA	0.626659530095474	0.126766855265291	63.1642102459344
a117	gain_cnaOV18_(CCNE1)	272	AR-42	HDAC	3	27	1.63315443905142	NA	2.70399041753787	0.0274430368561122	2.67654738068176	1.70297845050533	1.66051323780028	1.60890578959579	1.57168599513842	1.61187958021187	0.00961235459738164	NA	NA	0.432952294954329	0.100020278087701	63.1642102459344
a118	loss_cnaOV58	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	3.77890303723707	0.828965058697662	2.94993797853941	1.7268652141677	2.11711342266581	1.42554747893488	1.70826185757711	1.39337739157354	0.00982161640333978	NA	NA	0.310958447026613	0.0133031767409493	63.1642102459344
a119	gain_cnaOV26	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.82256297439142	4.70719995309239	1.11536302129903	0.858671409018382	0.659331903682477	1.65372086621373	1.29894044402164	1.69165637984381	0.00984104274983814	NA	NA	0.738774684678509	0.146265608258515	63.1642102459344
a120	KRAS_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	2.30258509299405	NA	1.13089948149078	2.46889451642794	-1.33799503493716	0.613896268855443	1.28604228775354	1.13499898793719	2.17951322204928	1.04039738636773	0.00987846160782063	NA	NA	0.651047508363425	0.000946001923877115	63.1642102459344
a121	PIK3R1_mut	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	4.53165120589691	3.37484820875471	1.1568029971422	0.592182969488772	0.89979180926588	1.33715894261671	1.95345536218453	1.2856340602678	0.0098883724131121	NA	NA	0.698338892668539	0.00653933544315487	63.1642102459344
a122	ARID1A_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	9	24	0.693147180559945	NA	1.28364053166444	1.90809392607967	-0.62445339441523	2.31706705505711	1.40880925980195	0.369373083008376	0.269501649964049	0.44324907014241	0.00990627236472129	NA	NA	0.182322498612741	0.465613601547698	63.1642102459344
a123	loss_cnaOV43_(NF1)	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	1.01490693658822	-2.77000923231867	3.78491616890689	3.47481734132352	2.05236481306689	1.66991625194229	1.0892417635585	1.84417319221674	0.00998964398246049	NA	NA	0.322815039541264	0.193878525029625	63.1642102459344
a124	loss_cnaOV83	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.77474151867993	5.02534609165251	0.749395427027419	0.471154795080828	0.52779911449243	1.43947648711917	1.59055035595861	1.41984972397707	0.01000657610977	NA	NA	0.00554884665169241	0.0184056528063229	63.1642102459344
a125	BRCA1_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	3.70381621746976	1.93905555166026	1.7647606658095	1.37698529848372	1.13450349262472	1.51880948639487	1.28161184273557	1.55553568347917	0.0101502219886842	NA	NA	0.651332460471842	0.0774395213418595	63.1642102459344
a126	loss_cnaOV40	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	2.30258509299405	NA	3.17654368189402	1.87224829131033	1.30429539058369	1.70927751790681	1.00550238284429	1.09984697722931	0.763068241944079	1.29715793103761	0.0101783232459842	NA	NA	0.651361467623167	0.0942943319236675	63.1642102459344
a127	gain_cnaOV48_(SOX17)	326	GSK690693	AKT	3	29	2.32630161961136	NA	2.41566316878388	4.33154507767716	-1.91588190889328	2.05534065436547	1.28725711489593	1.41696137650272	0.932148111226245	1.48834439268038	0.0102643871121261	NA	NA	0.0629361377022233	0.244917165491589	63.1642102459344
a128	loss_cnaOV38	1072	BMS-708163	g-secretase	8	25	1.6094379124341	NA	4.48349621899584	3.6358977118792	0.847598507116638	0.898151519208923	0.751512636901836	1.07697682800641	0.94371438336283	1.12785662608539	0.0102914689795288	NA	NA	0.915299869628584	0.0357768147730132	63.1642102459344
a129	SMARCA4_mut	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	4.98201871888853	6.04374281126608	-1.06172409237755	0.787253579533848	0.622500545086595	1.6735292269304	1.34864308017021	1.70557937781381	0.0102941026162392	NA	NA	0.898604067256924	0.137071307745659	63.1642102459344
a130	KRAS_mut	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	2.08755111614694	3.52267741146412	-1.43512629531717	0.904976447153967	0.848968645287329	1.67253403635696	1.58581618320616	1.69043498047147	0.0105457725157167	NA	NA	0.493866975760827	0.0406000563363803	63.1642102459344
a131	KRAS_mut	235	QL-XII-47	BTK, BMX	7	25	2.32630161961136	NA	0.0806324420456359	1.98099264748923	-1.90036020544359	0.978094087682893	1.50933431537367	1.33914359327685	1.94292167734655	1.25907175506913	0.0106061289594705	NA	NA	0.0516349588287499	0.00120312598052017	63.1642102459344
a132	loss_cnaOV35	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	4.47385042962308	5.32356767153868	-0.849717241915607	0.655412552166894	0.717384353108115	1.19773916957265	1.29646165473382	1.18446581422379	0.0106997043276044	NA	NA	0.282405005389821	0.0399023396609624	63.1642102459344
a133	loss_cnaOV43_(NF1)	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	2.35038738571209	1.47819401640968	0.872193369302415	0.845012476113398	0.561252349546905	1.43735855514158	1.03216626257879	1.55401286071503	0.0107788958372043	NA	NA	0.163190316490707	0.0809514349056421	63.1642102459344
a134	loss_cnaOV102	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-0.729973895540441	-3.5921752742346	2.86220137869416	0.865965599041815	1.65886880640507	1.77037655944998	3.30521371964564	1.72539345344423	0.0107835692873749	NA	NA	0.100105059351084	0.00925019122324426	63.1642102459344
a135	gain_cnaOV26	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	4.50712807126434	3.12119889827142	1.38592917299292	0.789159576508095	1.02750213070644	1.36765974489819	1.75620902824931	1.34883338104618	0.0108531777795413	NA	NA	0.0393334871798343	0.0744180863752646	63.1642102459344
a136	loss_cnaOV83	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	-0.113136847039974	1.45341584027604	-1.56655268731601	1.49517600125416	1.03618684227968	1.41620127575276	1.04773798268698	1.51184383298045	0.0108611395341193	NA	NA	0.219214215916058	0.0777083634420539	63.1642102459344
a137	loss_cnaOV40	1023	GW 441756	NTRK1	7	24	0.693147180559945	NA	1.26866471077608	2.59882811551797	-1.33016340474188	1.38138746465906	1.05377076440497	1.17778409738387	0.962918398184674	1.26228915213166	0.0108718984166441	NA	NA	0.82650365673184	0.0457223468187754	63.1642102459344
a138	PIK3CA_mut	223	ZSTK474	PI3K	6	26	1.63315443905142	2.32630161961136	-0.10864050582297	0.958319373334309	-1.06695987915728	0.969205145524359	0.964244009627532	1.10557468794003	1.10086072498102	1.10652476811282	0.0108748059886271	NA	NA	0.74695746234865	0.0431055737903114	63.1642102459344
a139	SMARCA4_mut	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	3.6883258026887	5.04193805825461	-1.3536122555659	0.398391923770079	0.782628817321404	1.77552599513466	3.39769000022978	1.72957119084718	0.010922155016933	NA	NA	0.112923745012554	0.00803923299626614	63.1642102459344
a140	loss_cnaOV85	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	2.21913860360673	1.44516820585499	0.773970397751746	0.811217178711455	0.541263963011927	1.27935457011552	0.954085315329648	1.42993151335052	0.0109800415350581	NA	NA	0.163424773146837	0.046285353914574	63.1642102459344
a141	loss_cnaOV43_(NF1)	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-2.25042476886103	-5.10478565295788	2.85436088409684	2.76220363746641	1.5968860442316	1.60884794545616	1.03336366855087	1.78745433614852	0.0109995496025368	NA	NA	0.258128135943043	0.210159276628374	63.1642102459344
a142	loss_cnaOV43_(NF1)	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	5.6993565243572	4.05941453112124	1.63994199323596	0.595469176150716	1.23583573697494	1.39805265680434	2.75403338899423	1.32699026591526	0.011052608045882	NA	NA	0.322072277691946	0.000646817297509739	63.1642102459344
a143	SMARCA4_mut	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	2.31059389189075	4.1473911693383	-1.83679727744755	0.736520382830151	1.053510295032	1.77507578246914	2.49388519349523	1.74350197250969	0.0111107422001959	NA	NA	0.0542625796447886	0.0303673096993852	63.1642102459344
a144	KRAS_mut	1005	Cisplatin	DNA crosslinker	7	24	1.79175946922805	2.30258509299405	1.98149841561192	3.32750543559891	-1.34600701998699	1.37086316070883	0.952101143314553	1.27886483371276	0.981868255392473	1.4137227220431	0.0111524324205974	NA	NA	0.0587299417553818	0.0419321035976229	63.1642102459344
a145	PIK3CA_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	4.19502607580591	5.33058335942987	-1.13555728362396	1.15323536496375	1.05531745469108	1.05226369913766	0.984670881697815	1.07603383093514	0.0111526534358684	NA	NA	0.758997165327624	0.0973951793462825	63.1642102459344
a146	loss_cnaOV102	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.98978650530277	2.39177040615032	1.59801609915244	0.256887900102922	0.959007998657847	1.71857647486169	6.22067484888234	1.66632197165081	0.0111654851076245	NA	NA	0.346572986133442	3.67838057255161e-05	63.1642102459344
a147	loss_cnaOV39	260	NG-25	MAP3K7 (TAK1)	9	23	2.32630161961136	NA	2.22474098622622	3.32003246049622	-1.09529147427	0.793634743481842	1.02019607504398	1.13502317534506	1.38009516753856	1.07360879056781	0.0112075263718006	NA	NA	0.385317067873239	0.00448077321229283	63.1642102459344
a148	loss_cnaOV43_(NF1)	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-1.34216499623185	-2.51069746666154	1.16853247042969	0.111266802123283	0.658359669687079	1.88595350908462	10.5020765235524	1.77491502628813	0.011266580291673	NA	NA	0.609893978754479	4.43365345176748e-06	63.1642102459344
a149	BRCA1_mut	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	4.51351515261756	3.33948228202009	1.17403287059748	0.594890488626157	0.84312852766166	1.42759197840037	1.97352772156232	1.39247200406508	0.0115386960324062	NA	NA	0.772731095988368	0.0182910235548047	63.1642102459344
a150	loss_cnaOV43_(NF1)	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	3.55218697262598	2.237921919321	1.31426505330497	0.755643924763644	0.689079809824411	1.8849514695581	1.73926502977717	1.90727552101675	0.0115698480322606	NA	NA	0.550149255610811	0.0776358374881293	63.1642102459344
a151	gain_cnaOV72_(ASXL1)	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.92068810211774	2.81969238423306	1.10099571788469	0.31880079189533	0.987829032464038	1.18516214620487	3.453553899095	1.11456100367729	0.0115958200680534	NA	NA	0.0600332346059102	0.000132862776643475	63.1642102459344
a152	gain_cnaOV18_(CCNE1)	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	5.42971413024763	4.38875102907337	1.04096310117426	0.360471665975772	0.617727327485975	1.72482979059214	2.88778064804745	1.68514983044504	0.0116057088844786	NA	NA	0.0325435008958204	0.0168013516581836	63.1642102459344
a153	loss_cnaOV43_(NF1)	1031	Elesclomol	HSP70	5	26	-1.6094379124341	NA	-2.56962419781869	-4.3463399931433	1.7767157953246	1.35333622004014	1.38546971629894	1.28646658643887	1.31284138340131	1.28239237164332	0.0116524548538391	NA	NA	0.848613775836528	0.0382688813117097	63.1642102459344
a154	KRAS_mut	1026	17-AAG	HSP90	7	26	0	NA	-2.57141205287143	0.0185547364049385	-2.58996678927637	1.25532296160502	2.1887873412082	1.26853415946669	2.0631876166472	1.18328845407463	0.0117062773569801	NA	NA	0.039556700026792	0.000827631073896762	63.1642102459344
a155	loss_cnaOV44	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	4.2190018766209	2.19512482285336	2.02387705376754	1.19878887245876	1.17116459400282	1.72543475094937	1.68826813483553	1.72808934297638	0.0118422167058658	NA	NA	0.078414910280655	0.0879804184441494	63.1642102459344
a156	loss_cnaOV39	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	21	2.30258509299405	NA	2.91715368376701	1.80943942509695	1.10771425867006	1.60263455443356	0.96371247189804	0.923861300430411	0.6911833116325	1.14942401491226	0.0118725372767009	NA	NA	0.652970462482346	0.0660338523638035	63.1642102459344
a157	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	225	Genentech Cpd 10	AURKA, AURKB	7	25	2.32630161961136	NA	4.32758858372577	2.42879040654481	1.89879817718096	1.07558095211365	1.80342358561245	1.12807195783126	1.76536984357113	1.05288529679294	0.0119377107667403	NA	NA	0.296671383737735	0.00286669287906522	63.1642102459344
a158	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	1.28462433043632	-1.58657388802642	2.87119821846274	0.771441834779605	1.72434021952278	1.71135200130425	3.72185962572671	1.66509960502885	0.0119647579575102	NA	NA	0.0488201724898339	0.00452835773602271	63.1642102459344
a159	loss_cnaOV41	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	3.6688259575243	4.5723602554242	-0.903534297899904	0.418108717300598	0.692245687052133	1.36427207328165	2.16100325229601	1.30522199675599	0.0120713095393496	NA	NA	0.480223706601453	0.00362802613187614	63.1642102459344
a160	loss_cnaOV52, loss_cnaOV53	1038	NU-7441	PRKDC (DNAPK)	9	24	0.693147180559945	NA	3.29429084671215	2.25307725333369	1.04121359337846	0.911857297379059	0.93296455771304	1.12252539812192	1.14186024103904	1.11602695383281	0.0120752720005639	NA	NA	0.347691348812991	0.01109846966173	63.1642102459344
a161	loss_cnaOV55	286	KIN001-236	TIE2	7	25	2.32630161961136	NA	5.34182888586691	4.64197840603471	0.699850479832202	0.395385170839533	0.640274916306907	1.16767101551129	1.77004736506984	1.09304684910808	0.0122165159095782	NA	NA	0.73704390974404	0.0026538818826923	63.1642102459344
a162	PIK3R1_mut	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	3.41280746858239	1.18257951197443	2.23022795660795	2.00849151851861	1.70031968586774	1.2783918472432	1.11039948939037	1.31165214115002	0.0123752868180327	NA	NA	0.759655236311864	0.0657708479615978	63.1642102459344
a163	loss_cnaOV81_(RB1)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	3.42506259077946	1.1930209359325	2.23204165484696	1.41877929693954	1.30444901190193	1.70040417452066	1.57321273270741	1.71109919550828	0.0124539172490311	NA	NA	0.428641764589948	0.101310289772997	63.1642102459344
a164	ARID1A_mut	326	GSK690693	AKT	8	24	2.32630161961136	NA	2.8735848099704	4.57804659496776	-1.70446178499736	1.52806836157734	1.16187775304253	1.35608241276474	1.115435557633	1.46698891560149	0.0125308788822703	NA	NA	0.0644877302235717	0.0163847428068469	63.1642102459344
a165	loss_cnaOV57_(ZNRF3)	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-0.68647855377217	-3.02442645348172	2.33794789970955	1.43881027764784	1.61087138043811	1.46625677674216	1.62491743076204	1.45135603506327	0.0125353538505949	NA	NA	0.665329858249723	0.0383167544461306	63.1642102459344
a166	loss_cnaOV82	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	1.81554113532781	4.1066938635824	-2.29115272825459	1.87354211886195	1.40608663415585	1.5875568463298	1.22289897045192	1.62945345798703	0.0126094056112222	NA	NA	0.685344270935625	0.161718093515054	63.1642102459344
a167	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	5.59193332847215	3.92803139087272	1.66390193759944	0.790893144607943	1.02638602885668	1.64353501016308	2.10382647636206	1.62112683806979	0.012796291332711	NA	NA	0.800609348628349	0.0496052785208193	63.1642102459344
a168	gain_cnaOV18_(CCNE1)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	2.08075253685818	-0.397619883136112	2.47837241999429	1.21218801868569	1.44945645638968	1.72786696013946	2.04454456057193	1.70986331398147	0.0127968562910319	NA	NA	0.0694157090919282	0.0546211194268396	63.1642102459344
a169	gain_cnaOV19	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	2.08075253685818	-0.397619883136112	2.47837241999429	1.21218801868569	1.44945645638968	1.72786696013946	2.04454456057193	1.70986331398147	0.0127968562910319	NA	NA	0.0694157090919282	0.0546211194268396	63.1642102459344
a170	loss_cnaOV85	1149	TW 37	BCL2, BCL2L1	7	26	1.6094379124341	NA	0.0840675923659385	-0.96236242262837	1.04643001499431	1.17235081749889	0.709696842742763	1.27632464261348	0.892591193160747	1.47447466576035	0.0130610503102956	NA	NA	0.0258747711092767	0.0577739551451302	63.1642102459344
a171	loss_cnaOV54	1038	NU-7441	PRKDC (DNAPK)	11	22	0.693147180559945	NA	3.18857219521219	2.21128079786745	0.977291397344735	0.851672268466474	0.963875598261697	1.05179805865719	1.14749702852771	1.01391860018786	0.0130661722997555	NA	NA	0.348814735967508	0.00693322593886627	63.1642102459344
a172	loss_cnaOV43_(NF1)	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-2.78855920809589	-4.44175681054566	1.65319760244977	2.26213505587888	0.934586634981954	1.3780032033881	0.730812953962853	1.76890781503813	0.0134005763526331	NA	NA	0.173992714396187	0.178632864147751	63.1642102459344
a173	TP53_mut	1059	AZD8055	MTORC1/2	23	10	0.693147180559945	NA	0.567922002475192	-0.378511160418945	0.946433162894137	1.0630103910968	1.04119775326063	0.895629413213695	0.890332936367275	0.908985022230673	0.0134367743401816	NA	NA	0.111072094055129	0.0286336707874989	63.1642102459344
a174	loss_cnaOV52, loss_cnaOV53	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.88491985887971	2.71987494842049	1.16504491045922	1.03282371162399	0.663922390274008	1.59999262449357	1.12801913564448	1.75479081218874	0.0135864844586304	NA	NA	0.261115159713019	0.105339006061157	63.1642102459344
a175	loss_cnaOV55	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.88491985887971	2.71987494842049	1.16504491045922	1.03282371162399	0.663922390274008	1.59999262449357	1.12801913564448	1.75479081218874	0.0135864844586304	NA	NA	0.261115159713019	0.105339006061157	63.1642102459344
a176	loss_cnaOV36	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	5.58054425028792	4.09420248454259	1.48634176574533	0.795835663494406	0.887944047833869	1.68463741223954	1.8676491063733	1.67391376671903	0.0136188763779485	NA	NA	0.167998122457874	0.0691723730257719	63.1642102459344
a177	ARID1A_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	9	22	-1.6094379124341	NA	-0.215099649179401	0.885126710355349	-1.10022635953475	1.23048568628126	1.05807097231506	0.992701077702313	0.894139908981653	1.03984173871385	0.0136669630784248	NA	NA	0.382793784189787	0.0350451087800962	63.1642102459344
a178	SMARCA4_mut	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	1.57363339040892	3.12779756992958	-1.55416417952066	0.523551467627182	0.92401290244222	1.72006686812062	2.96850314748306	1.68197237875458	0.0136868875022848	NA	NA	0.0612405205495828	0.0155497118543423	63.1642102459344
a179	ARID1A_mut	1053	MK-2206	AKT1, AKT2	9	23	1.38629436111989	0.693147180559945	0.340023572959426	1.68940514706526	-1.34938157410583	1.24720449958144	0.977248381849068	1.2778160253524	1.08192487644062	1.38079693880142	0.0137552008800906	NA	NA	0.0684318451823814	0.0129199191428919	63.1642102459344
a180	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	3.10704904980647	1.15746584367491	1.94958320613156	2.55730793194843	1.0849873412296	1.48140515656452	0.762357626852609	1.79687184545594	0.0138687587163006	NA	NA	0.430218970402776	0.224900980726062	63.1642102459344
a181	loss_cnaOV16, loss_cnaOV17	298	OSI-930	KIT, VEGFR, PDGFR	6	26	2.32630161961136	NA	5.38422684703064	4.23633672499712	1.14789012203352	0.67840611272507	0.91251802420463	1.30762143804123	1.69203976866098	1.25793693010507	0.0140229712586638	NA	NA	0.0183374082072403	0.0061768466114619	63.1642102459344
a182	loss_cnaOV38	1066	AZD6482	PI3Kbeta	8	25	1.6094379124341	NA	3.43672246040472	2.04067882528903	1.39604363511569	1.12633605235095	1.17491677305309	1.19922229023452	1.2394556954843	1.1882064050273	0.0140440338704384	NA	NA	0.079870643321321	0.0104269959949529	63.1642102459344
a183	BRCA1_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.96341967104241	2.12052778399455	1.84289188704786	1.36839468441104	1.44470117179252	1.28201735513423	1.34675463741738	1.27562150777609	0.0140700629209376	NA	NA	0.199002487991458	0.0664845985949158	63.1642102459344
a184	PIK3CA_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	6	26	2.32630161961136	NA	-0.846947250618028	1.78300981825886	-2.62995706887689	1.38729825905358	2.20757797977439	1.256364867011	1.89574019264686	1.19133144693972	0.0142453261339657	NA	NA	0.316454591538687	0.00320427963046456	63.1642102459344
a185	loss_cnaOV16, loss_cnaOV17	1069	EHT 1864	Rac GTPases	6	27	2.30258509299405	NA	5.15097111652114	4.02451409585239	1.12645702066875	0.728514790150518	0.904558653395818	1.2821720865925	1.54623768233452	1.24531119838377	0.0143160845794635	NA	NA	0.168613484032745	0.00997713515217421	63.1642102459344
a186	loss_cnaOV44	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	5.51855409570725	4.06032177789542	1.45823231781183	0.899519777476976	0.876700965969977	1.66040172680123	1.62112313072422	1.66331779525126	0.0143708811716612	NA	NA	0.0303176260805336	0.0949088186452084	63.1642102459344
a187	loss_cnaOV87, loss_cnaOV88	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	3.46072834300215	2.24788132448551	1.21284701851663	0.43502333449153	0.818127768775304	1.51923444791627	2.78800450999772	1.48246651049652	0.0143972739113247	NA	NA	0.571416061765952	0.0170092049596814	63.1642102459344
a188	loss_cnaOV87, loss_cnaOV88	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.43953339557005	4.53376746542637	-1.09423406985632	0.370816633028801	0.683278451239743	1.64048878346088	2.95087645049442	1.60144677162135	0.014539306237765	NA	NA	0.482729685867066	0.0146122173308683	63.1642102459344
a189	BRCA1_mut	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	5.12657591472359	4.1770676662904	0.949508248433185	0.141874308298386	0.777973154965618	1.28651481035492	6.69260178126265	1.22048973331882	0.0145441711250879	NA	NA	0.180475842175548	4.23335236195333e-06	63.1642102459344
a190	loss_cnaOV102	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.87358566054037	5.85458611710089	1.01899954343948	0.480952814230925	0.650120814804217	1.5908038559114	2.11871001330749	1.56740027428033	0.0145748860951062	NA	NA	0.89965077988408	0.048180811251823	63.1642102459344
a191	NF1_mut	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	2.21336093549739	4.24485989828734	-2.03149896278995	1.83768360847433	1.17438726849066	1.57456928570052	1.10546720524788	1.72983735203539	0.0145761273469235	NA	NA	0.0386895539141107	0.110245034708976	63.1642102459344
a192	loss_cnaOV43_(NF1)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	5	26	0.693147180559945	NA	1.52808525220341	-0.481981745317449	2.01006699752086	1.53621724157702	1.41314037010965	1.40490826495215	1.30845230942559	1.42241141788689	0.0145862594015415	NA	NA	0.0705242951157542	0.0389995424876636	63.1642102459344
a193	loss_cnaOV85	1032	Afatinib	ERBB2, EGFR	7	24	-0.693147180559945	NA	1.68201983796084	-0.0293403392789402	1.71136017723978	0.546791324656777	1.68291318179972	1.12645980540301	3.12982320689527	1.01690342422159	0.0145948125707505	NA	NA	0.820062073477215	0.000198790583253804	63.1642102459344
a194	loss_cnaOV59	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	5.51509208831288	4.22609778924853	1.28899429906436	0.510838032267141	0.923297847128843	1.44718814397513	2.52329352484524	1.39607636156925	0.0148740428238678	NA	NA	0.46949069856963	0.00529805965121086	63.1642102459344
a195	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.81692502279256	3.43566748359908	1.38125753919348	1.34189556992965	0.781177664749656	1.66641508804114	1.02933310918218	1.76817336378419	0.0148824346480058	NA	NA	0.108684537266803	0.213480830723433	63.1642102459344
a196	loss_cnaOV102	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	4.46233678841352	2.1320658018257	2.33027098658783	1.6384641759102	1.38735302000613	1.65866349337751	1.42222882919812	1.6796525130839	0.0149078788824037	NA	NA	0.199757753794129	0.124023878544168	63.1642102459344
a197	loss_cnaOV43_(NF1)	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.85833860886397	4.54434625966776	1.31399234919621	0.460352369766256	1.20648010837695	1.15958146609854	2.85431863827135	1.08911231944295	0.0149467530465778	NA	NA	0.377920619835996	0.000626627297242578	63.1642102459344
a198	KRAS_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	7	26	-1.38629436111989	0.693147180559945	-3.68386769104876	-1.92520491239978	-1.75866277864898	1.2145153371074	1.50106358425895	1.21284685750782	1.44803669819236	1.17161111434011	0.015002192822949	NA	NA	0.0926163121845867	0.00767789850713147	63.1642102459344
a199	PIK3R1_mut	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	-1.48490631564219	0.0921865545730415	-1.57709287021523	0.505176783117946	1.19889036187904	1.37526507007188	3.12186332174933	1.31546046274276	0.0150681800116608	NA	NA	0.743310359647148	0.00115301824565305	63.1642102459344
a200	ARID1A_mut	1038	NU-7441	PRKDC (DNAPK)	9	24	0.693147180559945	NA	1.85765356757595	2.79181623300977	-0.934162665433821	0.803960754694305	0.997494966469611	0.981957113418681	1.16195058027307	0.93650865100609	0.015074424028043	NA	NA	0.350844295344677	0.0125469421638431	63.1642102459344
a201	loss_cnaOV33_(ZFHX3)	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	5.3751073299078	4.07128544715552	1.30382188275228	0.76880009227418	0.894586466837415	1.47625279770094	1.69591795819828	1.45745764225745	0.0151099931611277	NA	NA	0.169278666062172	0.0333594536468017	63.1642102459344
a202	PTEN_mut	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	1.44942382336181	3.25677496556334	-1.80735114220153	1.31921793701916	0.987271199825184	1.76052117175751	1.37001710747303	1.83065316047056	0.0156106921132223	NA	NA	0.0613255408284749	0.0662405955378166	63.1642102459344
a203	SMAD4_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	2.23602952807684	0.673998810894622	1.56203071718222	2.04812820126845	0.985973293056911	1.37294556703768	0.762662569762392	1.5842525636159	0.0156341534053606	NA	NA	0.829483984302482	0.224838740343878	63.1642102459344
a204	KRAS_mut	1018	ABT-888	PARP1, PARP2	7	24	1.6094379124341	NA	3.633467786931	4.49386900584243	-0.860401218911424	0.685445763594558	0.725519642523174	1.1993122618704	1.25524332428488	1.18591030274407	0.0156438150911498	NA	NA	0.181460997613091	0.0158739368021592	63.1642102459344
a205	TP53_mut	326	GSK690693	AKT	22	10	2.32630161961136	NA	4.5297110076686	3.32081545902801	1.20889554864059	1.16396838514335	1.71031437238318	0.894637140304765	1.03859826784875	0.706826515733535	0.015704359300488	NA	NA	0.0662607948882269	0.0632571164476867	63.1642102459344
a206	gain_cnaOV19	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	2.67150967525904	0.661107232602084	2.01040244265695	1.67782648090683	1.18017929485746	1.64998786806775	1.19821832921029	1.70347204989709	0.015788543515087	NA	NA	0.127437895797722	0.168182046129791	63.1642102459344
a207	loss_cnaOV40	1038	NU-7441	PRKDC (DNAPK)	8	25	0.693147180559945	NA	3.32855681494005	2.2837606872359	1.04479612770414	0.728547712502412	0.988190011529917	1.11637978985368	1.43408058219754	1.05728262329488	0.0159002729687688	NA	NA	0.351599042725907	0.0053539311686892	63.1642102459344
a208	gain_cnaOV19	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	6.35348039765276	5.64903131476729	0.704449082885467	0.162612801445916	0.44581958290546	1.62786452962383	4.3320641217768	1.5801214435097	0.0159829425537415	NA	NA	0.336555321809101	0.00130307447971536	63.1642102459344
a209	loss_cnaOV38	1268	XAV 939	TNKS1 (tankyrase-1)	8	24	1.6094379124341	NA	3.51071144353547	2.63757973956884	0.873131703966631	1.1046456523029	0.977086522380514	0.865948864677002	0.790417906544398	0.893607356121734	0.0160711181649064	NA	NA	0.261874510475765	0.0721328528787906	63.1642102459344
a210	loss_cnaOV59	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.78337319426725	3.7114455093751	1.07192768489216	0.750958026376235	0.797865418121023	1.35097544774294	1.42741358004357	1.34349435449471	0.0161003489543159	NA	NA	0.916423859419213	0.0567024026701181	63.1642102459344
a211	loss_cnaOV43_(NF1)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	3.9372879088225	2.05937660271068	1.87791130611182	1.62725176736075	1.36684890789805	1.33833730157572	1.15403857213664	1.37389823795498	0.0161095917466963	NA	NA	0.200769413450763	0.0586596025611578	63.1642102459344
a212	TP53_mut	1010	Gefitinib	EGFR	20	10	-0.693147180559945	NA	1.31132139588054	0.153635223750141	1.1576861721304	1.03635506338365	1.35769132366758	1.007138804905	1.11707484532435	0.852687317028073	0.0161348809349819	NA	NA	0.95289605200107	0.0320386990906615	63.1642102459344
a213	gain_cnaOV18_(CCNE1)	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	4.50377172605277	3.40731566507827	1.0964560609745	0.99068956649363	0.811452437726355	1.31925532953838	1.10676048083882	1.35122652911945	0.016262149700436	NA	NA	0.63223543241403	0.109657682727963	63.1642102459344
a214	KRAS_mut	1006	Cytarabine	DNA synthesis	7	24	0.693147180559945	NA	-1.10629436176891	0.178894676803573	-1.28518903857248	1.30749711473383	1.09530742330485	1.12494434554337	0.982938336222724	1.17335919690447	0.0162662045574467	NA	NA	0.743914146448704	0.0431428225885335	63.1642102459344
a215	NF1_mut	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	5.21635043732168	4.14570093535573	1.07064950196594	0.39200953559286	0.767916774429677	1.45081628108224	2.73118229215198	1.39422595991747	0.0162772660573035	NA	NA	0.270377229508429	0.00318216443505059	63.1642102459344
a216	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	4.55265685435081	3.08834474532462	1.46431210902619	0.542007054493766	0.844567378229407	1.79708961383993	2.70164769422394	1.73380140740938	0.0163164233208419	NA	NA	0.122708387841865	0.0168726323885717	63.1642102459344
a217	PIK3CA_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	7	24	-1.6094379124341	NA	-0.380876912569092	0.841792882216113	-1.22266979478521	1.2714368744274	1.05404616147688	1.10895137598207	0.961644120425442	1.15997746538165	0.0164645736023549	NA	NA	0.385589272726653	0.046741330066956	63.1642102459344
a218	TP53_mut	282	EKB-569	EGFR	22	10	0.916290731874155	2.99573227355399	2.08449438724722	0.801658698227346	1.28283568901988	1.18793546327007	1.70697877206883	0.940123937905588	1.07988668465926	0.751524102121727	0.0165178366393752	NA	NA	0.281638521567594	0.0506249216417908	63.1642102459344
a219	loss_cnaOV40	1066	AZD6482	PI3Kbeta	8	25	1.6094379124341	NA	3.41695886260284	2.04700317658563	1.36995568601721	1.28229074333678	1.13538133127724	1.17073449816996	1.06836588592405	1.20660402657501	0.0165433965826546	NA	NA	0.0812765687230468	0.0209617867969422	63.1642102459344
a220	loss_cnaOV1	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	1.34982965852487	-1.3086507577818	2.65848041630668	1.36524078199706	1.84978570769876	1.4595028552411	1.94726120942408	1.43718291542753	0.0166001575761092	NA	NA	0.40034256450272	0.0580876536507825	63.1642102459344
a221	loss_cnaOV102	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	4.12212113645991	2.72487040995021	1.3972507265097	1.51857130243752	0.947815991588114	1.40273063247408	0.920108739225422	1.47417931213477	0.0166460128044123	NA	NA	0.262379893359561	0.249300611088646	63.1642102459344
a222	PIK3CA_mut	303	PIK-93	PI4K, PI3K	6	26	2.99573227355399	NA	2.32422490658207	3.03942247511691	-0.715197568534832	1.55801662660473	1.14624083880489	0.584061636150873	0.459043604748563	0.623950520974738	0.0167075894324796	NA	NA	0.18988170864646	0.327971528115881	63.1642102459344
a223	loss_cnaOV87, loss_cnaOV88	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.47725837977229	2.63728870984139	0.839969669930902	0.657232380398269	0.503795972752064	1.62959145251285	1.2780406063102	1.66728143010441	0.0167328358279647	NA	NA	0.102440970192116	0.150318270745945	63.1642102459344
a224	loss_cnaOV39	305	TPCA-1	IKK	9	23	2.99573227355399	NA	2.52906430761668	3.63672441727529	-1.10766010965861	0.957855353424766	1.185185656741	0.981056135414531	1.15639601083631	0.934587845675103	0.0167853107548681	NA	NA	0.992982355937038	0.0133143226030881	63.1642102459344
a225	loss_cnaOV36	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.94598876517118	3.73091487511444	1.21507389005673	0.907179564550639	0.785269900203126	1.53089760554764	1.33939733382178	1.54733282116433	0.0168115839611334	NA	NA	0.916530880728778	0.137454246093107	63.1642102459344
a226	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	5.03374358083777	3.24193515201558	1.79180842882219	0.158394707967705	1.1450803542633	1.61860413341735	11.3122998350899	1.56478837677289	0.0168213928164434	NA	NA	0.282213955007496	2.80215259463189e-08	63.1642102459344
a227	RB1_mut	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	4.61728205866769	3.36824002043499	1.24904203823269	0.509451209320967	0.851714876591671	1.49786165044875	2.45174025574992	1.46650254980988	0.016827462419983	NA	NA	0.775208384917301	0.0286384685629738	63.1642102459344
a228	ARID1A_mut	192	LFM-A13	BTK	5	14	2.77258872223978	NA	4.21307680461129	4.90794542707973	-0.694868622468441	0.787774854315728	0.559312441290783	1.11952712590969	0.882064994410126	1.24236217750641	0.0168296791893366	NA	NA	0.948810892353126	0.123652660794257	63.1642102459344
a229	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	272	AR-42	HDAC	7	23	1.63315443905142	NA	1.72249939000316	-0.139328803577977	1.86182819358114	2.17167343157704	1.50654176036767	1.113865651726	0.857324202851765	1.23582913036991	0.0168457502126944	NA	NA	0.441436106908825	0.0676853983612616	63.1642102459344
a230	loss_cnaOV41	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	5.45769571294125	4.26524582842232	1.19244988451893	0.748911377359174	0.90510701671107	1.34607231063818	1.59224431697615	1.31746839048049	0.0168462906074676	NA	NA	0.0189443419307399	0.0180276288086764	63.1642102459344
a231	loss_cnaOV102	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-1.37745047325716	-3.93906620230444	2.56161572904728	1.48426748527723	1.56318998057631	1.64430075778207	1.72584507472979	1.63871043243437	0.0169597721593364	NA	NA	0.201512461712298	0.0819895626665094	63.1642102459344
a232	loss_cnaOV102	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	0.269716375619177	-0.931701306097549	1.20141768171673	0.483408216558073	0.740621620327961	1.6552669595831	2.48530670469561	1.62217473638525	0.0169763633608422	NA	NA	0.054111193268255	0.0289276849923134	63.1642102459344
a233	loss_cnaOV35	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	2.1423094886984	3.45646684519157	-1.31415735649317	0.482639087209195	1.03424877716738	1.34258092052212	2.72285728885352	1.27063950715262	0.0171369584902502	NA	NA	0.0419773103774714	0.000710228353652757	63.1642102459344
a234	SMARCA4_mut	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	3.35801018229594	4.51155858418143	-1.15354840188549	0.787308796370934	0.686545886308262	1.66225750420411	1.46517911041097	1.6802203973407	0.0172149696156954	NA	NA	0.0270054250670782	0.116593866276926	63.1642102459344
a235	PTEN_mut	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	4.70411965991326	3.43678616159041	1.26733349832284	0.160960155023476	0.919627044810607	1.42490578858006	7.87358522447996	1.3780950717732	0.0172547121266166	NA	NA	0.703241399106748	1.80738101204164e-06	63.1642102459344
a236	loss_cnaOV102	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	2.0011683640548	-0.389093007478607	2.3902613715334	0.938779124700653	1.47903289456407	1.65043809560243	2.54613817951649	1.61609750555136	0.0172816744159854	NA	NA	0.0719697820968137	0.026421741157861	63.1642102459344
a237	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	306	TG101348	JAK2	7	25	2.32630161961136	NA	3.90650008508104	2.52097500752939	1.38552507755165	1.29395762229306	1.27418298357991	1.08399769248699	1.07076542050606	1.08738312738954	0.017305588672404	NA	NA	0.594452859334672	0.031856309184726	63.1642102459344
a238	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1248	FK866	NAMPT	5	27	0	NA	1.14218572133988	-2.23623616971455	3.37842189105443	1.84678346646683	2.55810105545353	1.3649647515162	1.82935463328457	1.32067569568923	0.0173813212842116	NA	NA	0.0285838026242356	0.0093582822236512	63.1642102459344
a239	loss_cnaOV102	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.94021859341773	3.73149189228979	1.20872670112794	0.81485356543072	0.79313324019564	1.52126731401927	1.48336676969563	1.52398946339682	0.0174489887044697	NA	NA	0.916622789075994	0.112677529558847	63.1642102459344
a240	SMARCA4_mut	1028	VX-702	p38	3	28	0.693147180559945	NA	2.10967088303439	3.45739404362733	-1.34772316059295	0.936532285898062	0.829961247042367	1.60874850703171	1.4390568065687	1.62383866161904	0.0174540530670209	NA	NA	0.477125582808728	0.12019004211806	63.1642102459344
a241	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	274	PXD101, Belinostat	HDAC	7	23	2.99573227355399	NA	2.44948404673131	0.369411511024458	2.08007253570685	2.6049429931893	1.63609801163041	1.10285489295646	0.798509810443168	1.27136181385247	0.0175391801485051	NA	NA	0.369510157961205	0.0833839426753665	63.1642102459344
a242	TP53_mut	1054	PD-0332991	CDK4, CDK6	23	10	1.38629436111989	0.693147180559945	2.71193856292199	1.30025872348388	1.41167983943811	1.54072475698285	1.96940972673141	0.842033715412798	0.916244016356663	0.716803527613854	0.0175505915614701	NA	NA	0.0822195994036433	0.0635538434387115	63.1642102459344
a243	loss_cnaOV57_(ZNRF3)	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	0.952172992643864	-1.34678839180976	2.29896138445362	1.41039771755865	1.86869367184317	1.25760880218736	1.63000929158695	1.23025053228016	0.0175862840538261	NA	NA	0.401168496799415	0.0361211841901342	63.1642102459344
a244	BRCA1_mut	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	3.55945611868003	2.3661754739412	1.19328064473883	0.383705433839662	1.00712355702634	1.2431371082954	3.10988727159247	1.18484036681869	0.0176623671969647	NA	NA	0.154363591777811	0.00113498895517537	63.1642102459344
a245	SMARCA4_mut	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	4.21399146738035	5.6757893502948	-1.46179788291445	1.93134805105762	0.75703765453283	1.65138258320117	0.756879570263867	1.93094474780984	0.0177328389766108	NA	NA	0.260707348372379	0.319626022202989	63.1642102459344
a246	loss_cnaOV34	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	2.43144134795837	4.16449403255764	-1.73305268459927	1.61138128768372	1.43727793427126	1.18497309730439	1.07550751510243	1.2057881383102	0.0178147605679281	NA	NA	0.688613436787021	0.0722455979820528	63.1642102459344
a247	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	2.8217107370101	1.02820511312399	1.79350562388612	2.12669595876937	1.47384098257768	1.09996990517204	0.84332958667206	1.21689221909772	0.0178944622946487	NA	NA	0.579890305087541	0.0711285873175507	63.1642102459344
a248	loss_cnaOV36	290	KIN001-260	IKK	3	28	2.99573227355399	NA	3.73808174130755	4.96940692261301	-1.23132518130546	0.540478623914856	0.845428011710176	1.48708869363753	2.27821254499686	1.45645183770842	0.0180121434704331	NA	NA	0.634421993758731	0.0358557157589579	63.1642102459344
a249	PIK3R1_mut	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	4.09622877019745	2.81119524505414	1.2850335251433	1.0372436784968	0.969274222834515	1.31312170548388	1.23889260718909	1.32576880192418	0.0180182967868985	NA	NA	0.392193242234695	0.0467553574697804	63.1642102459344
a250	loss_cnaOV56	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.78664930594085	3.43869505528426	1.34795425065659	1.66453494538866	0.74289319266879	1.61685450424188	0.809808321772329	1.81446574549184	0.0180361816925027	NA	NA	0.110629918509119	0.294863748272857	63.1642102459344
a251	KRAS_mut	1248	FK866	NAMPT	7	25	0	NA	-4.02135921045667	-1.06071734009587	-2.9606418703608	2.25909472102696	2.52799491280731	1.19546942956493	1.31054348576182	1.1711423370995	0.0180366352351607	NA	NA	0.028750680191202	0.0128953760844508	63.1642102459344
a252	loss_cnaOV102	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	5.18311850419671	4.37629432129103	0.806824182905686	0.40261703806869	0.512318357201938	1.59531570860825	2.00394942741602	1.57484925449912	0.0181673308428181	NA	NA	0.321406270998209	0.0559930653765551	63.1642102459344
a253	loss_cnaOV40	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	3.30098339479038	2.15847519799222	1.14250819679816	0.50534246966819	0.92835810445369	1.31503308851311	2.26085924966555	1.23067617045309	0.0181799545235985	NA	NA	0.331888981374612	0.00920911845343331	63.1642102459344
a254	TP53_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	23	10	1.6094379124341	NA	2.72789738062243	1.46073446656957	1.26716291405286	1.50463194499617	1.29094852183407	0.876412704070706	0.842174671531441	0.98157509197391	0.018180937466401	NA	NA	0.20234616136689	0.0231011535371765	63.1642102459344
a255	loss_cnaOV58	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	4.49611762330164	3.39429326642293	1.10182435687871	1.25907500655563	0.745607365568146	1.32764536546768	0.875106209830103	1.47775412068137	0.0182182353003156	NA	NA	0.110731730403342	0.122340614249256	63.1642102459344
a256	loss_cnaOV56	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	4.12401644354832	2.20462336616062	1.9193930773877	1.35053628664463	1.17630516423676	1.61521970816832	1.42120807590914	1.63171355167269	0.0182691724377623	NA	NA	0.0821316768968276	0.123753573281078	63.1642102459344
a257	loss_cnaOV43_(NF1)	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	4.19555155959743	1.63540342659818	2.56014813299925	0.680006346407253	1.32078896644016	2.11909996881603	3.76488858747502	1.93834760741488	0.0183149129904155	NA	NA	0.516304568141965	0.00356117622578174	63.1642102459344
a258	loss_cnaOV44	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	4.79374370834006	2.62233817526174	2.17140553307831	0.704326614695523	1.47209271141184	1.51316476771812	3.08295255038318	1.47504672514531	0.0184488318859865	NA	NA	0.965946007870712	0.010739424111624	63.1642102459344
a259	loss_cnaOV35	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	6.69744672425109	4.39753413325418	2.29991259099691	1.02345166557239	1.35619196447569	1.74050935882288	2.24721173296507	1.69586065338919	0.0188156117420357	NA	NA	0.0714846749210023	0.0344757554063511	63.1642102459344
a260	loss_cnaOV42	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	3.61342747480588	4.54800524231612	-0.934577767510243	0.461114505006058	0.691422055002942	1.3908382526993	2.02678024083837	1.35167479941939	0.0188309471934472	NA	NA	0.486179610710538	0.0158565047524166	63.1642102459344
a261	loss_cnaOV43_(NF1)	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	5.61809225255146	3.57267949314202	2.04541275940944	1.49721785946179	1.55222587512002	1.32410170373745	1.36614237299087	1.31772881266477	0.0189509655778745	NA	NA	0.112920888725258	0.0332159924481044	63.1642102459344
a262	loss_cnaOV58	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-1.03238927902874	-3.04695957471975	2.01457029569101	1.4665955170177	1.63705441033856	1.24712918977141	1.37363729284241	1.23060680388404	0.0191286410955687	NA	NA	0.669393588959348	0.032424406418055	63.1642102459344
a263	loss_cnaOV70	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	5.6303246539587	2.27243274393386	3.35789191002484	0.66876228709125	2.19283456223322	1.57980901152424	5.02105452840326	1.53130198139759	0.0191344956432821	NA	NA	0.343488201850541	0.000299053650209519	63.1642102459344
a264	loss_cnaOV57_(ZNRF3)	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	1.52650828006669	3.94912191397193	-2.42261363390524	4.23725027600081	1.37339082132076	1.29623628384149	0.571741926037878	1.76396521390427	0.0191475328167367	NA	NA	0.72461983159919	0.33666971325059	63.1642102459344
a265	BRCA1_mut	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	5.10155385675455	4.29597983247962	0.805574024274933	0.224314544280661	0.763592768138325	1.10867557038854	3.59126969166566	1.05497859315635	0.0192841928698668	NA	NA	0.0275151173285225	0.000455453196009354	63.1642102459344
a266	PIK3R1_mut	305	TPCA-1	IKK	5	27	2.99573227355399	NA	4.4160715614504	3.1231808355048	1.29289072594559	1.08885844826258	1.14999555475629	1.13209571186755	1.1873818199313	1.12425715090663	0.019311746565469	NA	NA	0.993012508114088	0.0535863833375951	63.1642102459344
a267	loss_cnaOV16, loss_cnaOV17	206	Ruxolitinib	JAK1, JAK2, TYK2	6	26	1.65632149833295	0.0237165266173161	4.94436803056653	4.33829548640887	0.606072544157657	0.485401048328885	0.508896865748053	1.20000866084301	1.24860163826225	1.19095358008692	0.0193479234020799	NA	NA	0.322324847491789	0.0265327361256736	63.1642102459344
a268	loss_cnaOV42	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	1.33223509245718	0.540934556935305	0.791300535521872	0.607284883913398	0.555144356613695	1.41158302034358	1.30301371972683	1.42539598231476	0.0195087668962925	NA	NA	0.00847642732036429	0.0736047081255023	63.1642102459344
a269	gain_cnaOV26	305	TPCA-1	IKK	3	29	2.99573227355399	NA	4.87072152316375	3.16531295849622	1.70540856466753	1.70154709492713	1.07705482098018	1.50990414082379	1.00226938751911	1.58339996390853	0.0195822943726304	NA	NA	0.993015485371912	0.221230765286819	63.1642102459344
a270	loss_cnaOV82	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	1.60912508875388	3.1571048345237	-1.54797974576982	0.711238456269904	1.00303594419098	1.56952573103225	2.17645675950682	1.54329439013113	0.0195856322910901	NA	NA	0.393388552052303	0.0436755975284753	63.1642102459344
a271	loss_cnaOV59	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-2.68123820958345	-4.39804561024566	1.71680740066221	2.44423490663412	0.990137171504883	1.41132005092835	0.702390509194703	1.73390864424661	0.0196449243815481	NA	NA	0.178931191185468	0.255230818022525	63.1642102459344
a272	loss_cnaOV87, loss_cnaOV88	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.51136333985408	5.69423645092936	0.817126888924727	0.306753915697614	0.523660786643377	1.59700411409697	2.66378633526627	1.56041259870238	0.0196701186167249	NA	NA	0.0815733611693459	0.0214423347476311	63.1642102459344
a273	loss_cnaOV42	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	0.315021537886412	-0.885966758390404	1.20098829627682	1.38169160454798	0.757815998591903	1.43192309398348	0.869215888931825	1.58480198162664	0.0197561803576104	NA	NA	0.0275996595889126	0.179867925142422	63.1642102459344
a274	loss_cnaOV35	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.88773077521291	2.70845293561015	1.17927783960276	1.16627782102636	0.983678940546573	1.17524063700861	1.01114658818167	1.19884424784727	0.0199024468973688	NA	NA	0.264942759527402	0.133364174741405	63.1642102459344
a275	gain_cnaOV96	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	0.101751615345291	-0.951314589083519	1.05306620442881	0.578987310602145	0.742124436553477	1.44861301945387	1.81880705353218	1.41898872016583	0.0200074430838941	NA	NA	0.0552951010746643	0.0252334550885893	63.1642102459344
a276	loss_cnaOV102	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	4.31355839512082	2.85380506945839	1.45975332566242	0.248387121622957	0.946154675046374	1.59136400492112	5.8769283855154	1.54282736656232	0.0200825448489779	NA	NA	0.0640663881686989	5.50887576967592e-05	63.1642102459344
a277	PIK3R1_mut	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	2.11710712740275	4.03887790577136	-1.92177077836861	1.48285141897615	1.39117076833713	1.36942915274824	1.29599685698484	1.38140537603856	0.0200856417134744	NA	NA	0.131760909906711	0.0403213616382982	63.1642102459344
a278	loss_cnaOV83	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.69500710453771	4.80242303911793	0.892584065419786	0.497839358048363	0.787755875815843	1.17970628187806	1.79291582915201	1.13307192345011	0.0201759246234206	NA	NA	0.941175619308505	0.0100983649221649	63.1642102459344
a279	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	312	AV-951	VEGFR	7	25	-2.05572501506252	NA	1.05210251156816	0.524415615321606	0.527686896246551	0.519081213208472	0.594399921663903	0.909618337202293	1.01657868329483	0.887764074344758	0.0203164617851197	NA	NA	0.00854911253413078	0.0423187288094949	63.1642102459344
a280	loss_cnaOV57_(ZNRF3)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	3.71128510767926	2.08383224202833	1.62745286565093	1.30972637953311	1.30612310220189	1.2456620396672	1.24258997228954	1.24601797710134	0.0203367379650954	NA	NA	0.491676493168434	0.0821386626631016	63.1642102459344
a281	PIK3CA_mut	306	TG101348	JAK2	6	26	2.32630161961136	NA	1.70174007046792	3.0830552061921	-1.38131513572418	0.730024283999052	1.37902705277573	1.06774809977512	1.89214957091204	1.00165920091548	0.0204051980991698	NA	NA	0.596303157117686	0.00381972192156921	63.1642102459344
a282	gain_cnaOV4_(KRAS)	1058	GDC0941	PI3K (class 1)	7	26	1.38629436111989	0.693147180559945	1.85154096277179	0.572575356324505	1.27896560644728	1.55040458636809	1.15932722637864	1.02757311402646	0.82492377647265	1.10319638609917	0.0205770374518437	NA	NA	0.130329909023697	0.0767413882322786	63.1642102459344
a283	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	155	AP-24534	ABL	3	16	-0.669430653942629	NA	2.20646074544988	0.522692733593423	1.68376801185646	0.750173707623115	1.13618704538913	1.5337083102581	2.24450416583032	1.48194614494991	0.0206346488092561	NA	NA	0.521058157709248	0.0314424404144696	63.1642102459344
a284	SMARCA4_mut	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	1.18678495085076	2.67207056159552	-1.48528561074476	0.383061587833907	0.973044556023739	1.56982232537277	3.87740681372828	1.52643124258796	0.0206433533043901	NA	NA	0.355273137125762	0.0028926025341492	63.1642102459344
a285	PIK3R1_mut	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	3.43435369532359	4.62197945590294	-1.18762576057935	1.20223472072861	0.868183080876516	1.29351046589024	0.987848495890712	1.36794391268294	0.0206609124326206	NA	NA	0.334827507374816	0.0909501650106007	63.1642102459344
a286	loss_cnaOV102	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.43203525379416	0.557896627677061	0.874138626117101	0.642400524957426	0.557934039972758	1.550004243535	1.36073772071564	1.56674187895003	0.0207490416029867	NA	NA	0.00858701629058263	0.133421231547536	63.1642102459344
a287	PIK3R1_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	3.65052828276023	2.03292190583388	1.61760637692635	1.56188581328046	1.23284122874585	1.26055171283975	1.03567518391684	1.31209626934031	0.0207524149627032	NA	NA	0.49195178510945	0.0802056521620954	63.1642102459344
a288	PIK3R1_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	4.51915916113182	3.29162080610619	1.22753835502562	1.58892659537688	0.898462100268595	1.20132072701663	0.772558253224066	1.36626615041263	0.0207710959114004	NA	NA	0.702142734176278	0.160853700410763	63.1642102459344
a289	loss_cnaOV43_(NF1)	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	3.29830819021739	1.65077972384805	1.64752846636934	1.0393568018238	1.27854639771913	1.31775164264202	1.58514233368017	1.28859497731835	0.0207793755759454	NA	NA	0.0221151735089244	0.0183575139266622	63.1642102459344
a290	loss_cnaOV58	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.63564292826671	3.69954278241476	0.936100145851954	0.729434455929468	0.809880153135457	1.17019133809929	1.28332318036601	1.15585021095755	0.020786532895628	NA	NA	0.917052229603294	0.0413315368971745	63.1642102459344
a291	loss_cnaOV87, loss_cnaOV88	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.8932982906158	5.06476404124724	0.828534249368557	0.605999388339961	0.531145372437942	1.54444543091483	1.36721961327089	1.55990109744458	0.0208210701498867	NA	NA	0.00655501981921793	0.132173116539357	63.1642102459344
a292	loss_cnaOV56	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	4.07920604985546	2.72930990166791	1.34989614818754	1.34919577857713	0.972461632569005	1.34721015248125	1.00051910154296	1.38812278343717	0.0208538737960077	NA	NA	0.265610733962887	0.220934371634243	63.1642102459344
a293	SMAD4_mut	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	3.68645722525578	4.48391145110078	-0.797454225845005	0.775914717227698	0.574714390315893	1.35100988605392	1.0277601495874	1.38756613594917	0.0209501748160822	NA	NA	0.23081509074454	0.212236053149422	63.1642102459344
a294	loss_cnaOV83	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	5.16155940688781	4.3602451603984	0.801314246489407	0.585449348178782	0.614336964825568	1.31269650598084	1.36871660884437	1.30435622853482	0.0209561774653944	NA	NA	0.0356646351099112	0.0329594938099381	63.1642102459344
a295	loss_cnaOV56	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	5.45693925020575	4.06669572743006	1.39024352277569	0.962272392832109	0.882645958895828	1.56527842449724	1.44475050217746	1.57508626053742	0.020973838461193	NA	NA	0.0321290960962875	0.119045842308556	63.1642102459344
a296	TP53_mut	312	AV-951	VEGFR	22	10	-2.05572501506252	NA	0.782096009117461	0.326899576343312	0.455196432774149	0.589943014812049	0.566246957735581	0.780869501007393	0.771593902029962	0.803883228961577	0.0210303723850131	NA	NA	0.00861130082721121	0.0519227578903068	63.1642102459344
a297	loss_cnaOV42	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	5.32642890582299	4.07799971254653	1.24842919327646	0.824945272142241	0.899136359170653	1.39922940964977	1.51334789765448	1.38847593086769	0.0210861799564428	NA	NA	0.17338280413962	0.0478261426269292	63.1642102459344
a298	KRAS_mut	261	TL-1-85	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	4.28915031025441	3.35020421976324	0.938946090491174	0.953980774891077	0.861603373351921	1.06594946813099	0.984240055150357	1.08976603334126	0.0211643219838704	NA	NA	0.705001774120595	0.0435271424565436	63.1642102459344
a299	loss_cnaOV102	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	4.62311225526888	3.36765700077487	1.25545525449401	0.715828779213305	0.84051673251443	1.50708451154611	1.75384853326762	1.49367074554039	0.0211949860253931	NA	NA	0.776697015057051	0.0776346520039067	63.1642102459344
a300	gain_cnaOV72_(ASXL1)	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	2.01898669998384	0.634029017997159	1.38495768198668	1.59876129404941	1.19696166038765	1.10262935305589	0.866269209256873	1.15706102193628	0.0212495716559273	NA	NA	0.130681347183235	0.126059312713583	63.1642102459344
a301	TP53_mut	1036	PLX4720	BRAF	23	10	2.30258509299405	NA	4.63105361314688	3.56461563908026	1.06643797406663	1.11017085719205	1.45387103037365	0.874150193943928	0.960607069765786	0.733516214153156	0.021307806035281	NA	NA	0.33138660940735	0.0575504653998276	63.1642102459344
a302	loss_cnaOV40	1047	Nutlin-3a	MDM2	8	25	2.07944154167984	1.38629436111989	4.93619947585343	3.36738084767137	1.56881862818206	0.782543107287243	1.5480526927119	1.11109943359685	2.00476959489236	1.01341423038629	0.0213262399055462	NA	NA	0.13241971113616	0.000902927912996916	63.1642102459344
a303	gain_cnaOV18_(CCNE1)	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	3.13953026978708	0.347094610012108	2.79243565977498	1.0241767885715	2.2143524609956	1.31375429816329	2.72651722918835	1.26106196233975	0.0213289395250862	NA	NA	0.940948892931452	0.00294670671434678	63.1642102459344
a304	SMARCA4_mut	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	3.42950540823511	4.70832668795309	-1.27882127971798	1.26938853162396	0.835265357726806	1.46828078872011	1.00743093848654	1.5310359371282	0.0214547393356269	NA	NA	0.938019650378878	0.219364015059153	63.1642102459344
a305	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	8	23	2.30258509299405	NA	2.43157605291733	1.0533550241352	1.37822102878213	2.22525796393841	0.892685987630855	1.02732480829245	0.619353374357936	1.54390350904897	0.0214787022645791	NA	NA	0.436558559654518	0.127620176213981	63.1642102459344
a306	gain_cnaOV26	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	4.63406431050848	3.43164595154749	1.20241835896098	1.14986319377259	0.809657626990375	1.43717700584195	1.04570558086651	1.48509483376395	0.0215208829972381	NA	NA	0.63514068666404	0.207262135995285	63.1642102459344
a307	loss_cnaOV82	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.49197770980747	4.52834219153974	-1.03636448173227	0.55777170845791	0.682964888948224	1.53457933475441	1.8580441890779	1.51744913758054	0.0216517521512742	NA	NA	0.488023910078782	0.0672954459251125	63.1642102459344
a308	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.53928845824319	4.57242216421519	0.966866294028003	0.431754653830199	0.610657798204679	1.6320589813314	2.23938823924815	1.58331932691365	0.0217077827018957	NA	NA	0.949537629815262	0.0332175269313145	63.1642102459344
a309	loss_cnaOV40	260	NG-25	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	2.15977379494327	3.25059995611385	-1.09082616117058	0.823222443410104	1.02313501274234	1.10586691440862	1.32506853998289	1.06616052386557	0.0217850758187797	NA	NA	0.394907808967023	0.0128627799866355	63.1642102459344
a310	loss_cnaOV1	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	2.49645548001297	3.80098259530963	-1.30452711529666	0.139347255560871	0.828180598861384	1.65777206084706	9.36169937503225	1.57517227171245	0.0218005002754382	NA	NA	0.0339897156542563	4.12157567942517e-06	63.1642102459344
a311	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	158	PF-562271	FAK	3	15	0.940007258491471	NA	3.86701230327719	1.97392533892702	1.89308696435017	1.15056528727224	1.20656102576857	1.57796104703318	1.64535379720894	1.56899396211168	0.021801871060298	NA	NA	0.70262398892271	0.0829954151726843	63.1642102459344
a312	NF1_mut	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	4.47076089538736	3.05240493710523	1.41835595828213	0.61032764265927	1.18719820177594	1.241240542585	2.3239254773095	1.19470864777288	0.0218597667774206	NA	NA	0.568879987542734	0.00741810204027429	63.1642102459344
a313	loss_cnaOV57_(ZNRF3)	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	3.31257497384939	1.45089870022553	1.86167627362386	0.2235502928414	1.42585383139324	1.37440786586496	8.3277738085749	1.30565716669903	0.0219812878393882	NA	NA	0.285772318369363	5.37647721378411e-07	63.1642102459344
a314	loss_cnaOV43_(NF1)	1061	SB590885	BRAF	5	28	1.6094379124341	NA	5.04524511301139	3.72794959412136	1.31729551889002	0.542695127689801	1.26730493001746	1.09895642148713	2.42732144011983	1.03944637765425	0.0219946653763629	NA	NA	0.540704907099665	0.00179517423503913	63.1642102459344
a315	loss_cnaOV59	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	1.87549153488469	0.598660519007694	1.276831015877	0.355691988034649	1.007473570959	1.32675805278284	3.5897098018205	1.26735931609759	0.0220287928633585	NA	NA	0.752218128029062	0.000360423630590798	63.1642102459344
a316	PIK3R1_mut	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	3.43624429070316	4.54269236078353	-1.10644807008037	0.798491013775803	0.661987550569721	1.6334099321012	1.38567379092764	1.67140313911967	0.0221457013172984	NA	NA	0.0281429877653956	0.063494294078003	63.1642102459344
a317	gain_cnaOV18_(CCNE1)	308	XL-880	MET	4	28	1.63315443905142	NA	1.19480355392073	0.118569093106672	1.07623446081405	2.26509085598665	0.587418837548663	1.18588850086541	0.475139643060921	1.83214155219341	0.022330745823843	NA	NA	0.327869427670699	0.412849608069166	63.1642102459344
a318	gain_cnaOV96	1026	17-AAG	HSP90	4	29	0	NA	2.05048295776966	-0.886875622574147	2.93735858034381	1.47179036565695	2.14968860783209	1.40295082077165	1.9957723931918	1.36641119538986	0.0223503246511944	NA	NA	0.0432057351629441	0.0172452222306064	63.1642102459344
a319	loss_cnaOV83	1032	Afatinib	ERBB2, EGFR	5	26	-0.693147180559945	NA	1.90377760711054	0.0596570264414863	1.84412058066905	0.419311722127772	1.64732192274238	1.19950023400358	4.39797049152639	1.11946581612843	0.0223753142240932	NA	NA	0.822448995127032	3.916906761203e-05	63.1642102459344
a320	loss_cnaOV56	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	4.2567587282371	0.982975709872792	3.27378301836431	1.8212411999889	2.14978668487893	1.53737618377662	1.79755598455836	1.52284086667356	0.0225604896180048	NA	NA	0.323170845761842	0.0731964679963761	63.1642102459344
a321	ARID1A_mut	1058	GDC0941	PI3K (class 1)	9	24	1.38629436111989	0.693147180559945	-0.132609915602468	1.21005146851091	-1.34266138411338	1.07398735780795	1.25139229725288	1.11137628541899	1.25016498039027	1.07293403280558	0.0225846735228268	NA	NA	0.131347315931259	0.00730141329091326	63.1642102459344
a322	SMARCA4_mut	254	AC220	FLT3	3	29	0.0237165266173161	NA	1.76057911962307	2.58843053797919	-0.827851418356116	1.20675537944676	0.510807582053654	1.41847464472631	0.686014276344595	1.62067175085346	0.0226485352507614	NA	NA	0.845712109865454	0.356457415857743	63.1642102459344
a323	loss_cnaOV70	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	1.98020260198846	4.08905156358304	-2.10884896159458	2.08214304524473	1.41296067976999	1.43563500274004	1.01282616792868	1.49250364273256	0.0226499579136225	NA	NA	0.690846682711302	0.21735438773712	63.1642102459344
a324	loss_cnaOV39	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	23	1.38629436111989	0.693147180559945	3.70714823999125	2.43390843404174	1.27323980594951	1.2446108462687	1.52934244134032	0.876621225420741	1.02300233825427	0.832540686462369	0.0226597529849088	NA	NA	0.966152103928978	0.0201815394518817	63.1642102459344
a325	loss_cnaOV39	1009	ATRA	Retinoic acid and retinoid X receptor agonist	10	21	2.30258509299405	NA	4.9762220934826	4.290447036773	0.685775056709605	0.975412083497202	0.816040599294138	0.789485368837723	0.703061883599858	0.840368796972588	0.0226682851108742	NA	NA	0.491576148230748	0.0730457851472751	63.1642102459344
a326	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.42236137493787	0.558897373765642	0.863464001172233	0.655453694122725	0.558463352599033	1.52704621631781	1.31735316913259	1.54614263792558	0.0227778126025085	NA	NA	0.00875611141040938	0.141437343527193	63.1642102459344
a327	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	238	CAL-101	PI3Kdelta	7	25	2.99573227355399	2.32630161961136	5.11640520101106	4.18305080180531	0.933354399205741	0.954651124420318	0.898675244529934	1.02549978743622	0.977691614591132	1.03858919547066	0.0227865593975892	NA	NA	0.475235806758402	0.0452221617531035	63.1642102459344
a328	loss_cnaOV102	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	3.79182246621908	1.50188905017139	2.28993341604769	0.485044110161446	1.49972745390135	1.57634619194127	4.72108282128298	1.52689971107132	0.0227891583093906	NA	NA	0.0268876595552181	0.000518514348132361	63.1642102459344
a329	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	309	Y-39983	ROCK	7	25	2.99573227355399	NA	5.87068289907219	4.71049947140272	1.16018342766947	0.528649665711284	1.25249446652292	1.01331357988567	2.19461678105571	0.926298246163342	0.0228747072365012	NA	NA	0.332553853486119	0.00133120020425719	63.1642102459344
a330	BRCA1_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	5.01726988079685	4.07985408296077	0.937415797836083	0.671292080873784	0.952442169262621	1.00996411302625	1.39643506089913	0.984223324090982	0.0228766166434537	NA	NA	0.0325523415135485	0.0578539856008408	63.1642102459344
a331	loss_cnaOV39	273	CUDC-101	HDAC, EGFR	9	22	1.63315443905142	NA	-0.949936155068008	0.554987293701293	-1.5049234487693	0.914231599877045	1.64110035728633	1.01906957232648	1.64610745129757	0.917020974425836	0.0229743353538551	NA	NA	0.422431422353492	0.00324766793172047	63.1642102459344
a332	RB1_mut	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	0.662543407206763	2.55077066979478	-1.88822726258801	0.655872337112694	1.22105550303903	1.58315133026818	2.87895548530136	1.54638938024397	0.0229745999440088	NA	NA	0.0841151668821851	0.0159163038506608	63.1642102459344
a333	loss_cnaOV85	1494	SN-38	TOP1	7	25	-2.99573227355399	NA	-3.11148842372534	-4.4835924383654	1.37210401464006	1.90326917597736	0.972077533457921	1.12769703080337	0.72091957982531	1.41151705230667	0.0230252874749668	NA	NA	0.180977446728521	0.108753795315316	63.1642102459344
a334	loss_cnaOV41	1248	FK866	NAMPT	5	27	0	NA	1.04332566567647	-2.2179287519991	3.26125441767557	2.02905795178299	2.56152773004367	1.30601645154721	1.60727514697637	1.27316771917982	0.0230700909637136	NA	NA	0.0298727587810077	0.0171915294606692	63.1642102459344
a335	PIK3CA_mut	256	JW-7-24-1	LCK	6	26	2.32630161961136	NA	0.953164426823705	2.16692415532652	-1.21375972850282	1.06032554599839	1.29791693322377	0.962209430196933	1.14470478720755	0.935159791380548	0.0230805461104385	NA	NA	0.825143187716386	0.0392531504031969	63.1642102459344
a336	PIK3R1_mut	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	4.24576566844782	3.12775147443394	1.11801419401388	1.30766510662856	0.985640674813298	1.08084821267157	0.854969814784128	1.1343020053689	0.0231816437025624	NA	NA	0.946629244999244	0.130121189244258	63.1642102459344
a337	loss_cnaOV83	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.94419681670233	3.71490098883571	1.22929582786662	0.562951846157125	1.0311786521837	1.25008390294841	2.18366070962935	1.19212691735168	0.0232048345715899	NA	NA	0.277933458864836	0.00332939258789143	63.1642102459344
a338	PIK3CA_mut	265	Tubastatin A	HDAC6	6	25	2.99573227355399	NA	4.11790942251877	4.90948957042276	-0.791580147903984	1.47964575340226	1.12730031518631	0.662143390464151	0.534979501738064	0.70219101089594	0.0235451669929858	NA	NA	0.384702389753355	0.262382613849007	63.1642102459344
a339	gain_cnaOV26	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	4.29123912657113	2.76195229009719	1.52928683647394	1.43336246362775	1.14968837136722	1.3062561847934	1.06692262095619	1.33017509314745	0.023603312090292	NA	NA	0.19444634088155	0.200004500294898	63.1642102459344
a340	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	5.66713268182666	4.49061529262062	1.17651738920604	0.416819362061776	1.24994206558189	1.04191878224969	2.82260733615267	0.94125753633096	0.0236391443024276	NA	NA	0.38476128344032	0.000511284833940351	63.1642102459344
a341	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.47811945907971	-4.35985763958528	1.88173818050557	2.95192870126902	0.993805644128524	1.53503557962078	0.637460579483718	1.8934669888655	0.0236575645881414	NA	NA	0.181326241267928	0.38458803447462	63.1642102459344
a342	SMARCA4_mut	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.02601536066155	4.94634476559131	-0.920329404929756	0.297065946347132	0.575032982586257	1.64108708866063	3.09806430607943	1.60048107291255	0.0236873253249366	NA	NA	0.0338947787140424	0.0116169349418042	63.1642102459344
a343	gain_cnaOV96	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	4.27350071805829	2.00976452792453	2.26373619013376	0.82702183439702	1.70037484456871	1.38340000465162	2.73721454015086	1.33131597268951	0.0237709985777158	NA	NA	0.0848528631137603	0.00307961075484732	63.1642102459344
a344	gain_cnaOV72_(ASXL1)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	3.69766270365619	2.10216681791895	1.59549588573725	1.07440402266535	1.49789292867976	1.10017891774595	1.48500550265923	1.06516016945451	0.0237920335679263	NA	NA	0.20584296854425	0.0238252447148716	63.1642102459344
a345	TP53_mut	1050	ZM-447439	AURKB	16	6	1.38629436111989	0.693147180559945	2.86561047120643	1.33603458885315	1.52957588235328	1.61658150209028	0.610054201573855	1.06751003872134	0.946179255654908	2.50727866213721	0.0238668330805212	NA	NA	0.172487499261246	0.00428894043530682	63.1642102459344
a346	PIK3R1_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	3.76118637890199	2.69757861577562	1.06360776312637	1.04725145177989	0.636099361973181	1.50884692693455	1.01561832291441	1.67207802225592	0.0238865208176353	NA	NA	0.0117893468189235	0.0845829734781218	63.1642102459344
a347	loss_cnaOV102	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.97404256405065	4.80784310380668	1.16619946024398	0.539504425465175	0.743764371854808	1.6045925123891	2.16161240797691	1.56796897562556	0.023999997028896	NA	NA	0.39894021961994	0.0401484801185366	63.1642102459344
a348	gain_cnaOV18_(CCNE1)	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	5.64333910260149	4.37515090116008	1.26818820144141	0.306511109060066	0.974533534927992	1.36424357328653	4.1374950661018	1.3013284366198	0.0242235339285328	NA	NA	0.156907737908162	9.98802362748084e-05	63.1642102459344
a349	gain_cnaOV18_(CCNE1)	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	1.98429125079183	-0.0818778102342543	2.06616906102608	1.79992681674367	1.48650972849241	1.3681296637182	1.14791837190586	1.3899465448649	0.0242431187895379	NA	NA	0.423208496679934	0.177966064865204	63.1642102459344
a350	SMAD4_mut	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.94801100576754	3.75676440509798	1.19124660066957	0.637577168949243	1.03821301510099	1.18362851589451	1.86839595061535	1.1474009508094	0.0242846144288648	NA	NA	0.278563295596057	0.0209650699905656	63.1642102459344
a351	loss_cnaOV43_(NF1)	151	QS11	ARFGAP	3	16	2.32630161961136	NA	5.49217240267261	3.4432683026297	2.04890410004292	1.1764309399554	1.25924172246514	1.63940643200125	1.74162717968008	1.62709356233202	0.0242923752823776	NA	NA	0.034569767590518	0.0733221190634085	63.1642102459344
a352	gain_cnaOV4_(KRAS)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	1.6094379124341	NA	2.32841731377602	1.05157955032779	1.27683776344823	1.30388531061743	1.23137819925277	1.02415292401272	0.9792561915155	1.0369176295496	0.024420935185548	NA	NA	0.547769304761381	0.0453263683410945	63.1642102459344
a353	loss_cnaOV54	1049	PD-173074	FGFR1, FGFR3	11	22	0.693147180559945	NA	3.61482570463228	2.67235202355269	0.942473681079594	0.631930927860454	1.00921197490767	1.04156580509496	1.49141882368466	0.933870885911569	0.0244816193737434	NA	NA	0.0655425854074406	0.00269498935432625	63.1642102459344
a354	loss_cnaOV16, loss_cnaOV17	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	4.49249209664944	3.09962563739363	1.39286645925582	0.623238768429327	0.8573527233543	1.67164487194259	2.23488417250758	1.62461309250454	0.0244828107420198	NA	NA	0.130745830869685	0.0340829982064508	63.1642102459344
a355	SMAD4_mut	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	3.24176526211106	2.15357368038069	1.08819158173038	0.560663974133376	0.851590610484643	1.31701063002149	1.94089799226427	1.27783417094169	0.0245277237152563	NA	NA	0.562166262055358	0.0184246058597814	63.1642102459344
a356	gain_cnaOV72_(ASXL1)	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	2.46304148168811	0.754579841112886	1.70846164057522	0.504979211576066	1.20161065099425	1.46556001263781	3.3832316289675	1.42180966785005	0.0246187370437852	NA	NA	0.953545751795755	0.00546858504356669	63.1642102459344
a357	loss_cnaOV52, loss_cnaOV53	1019	Bosutinib	SRC, ABL, TEC	8	23	0.693147180559945	NA	2.94915099267114	1.29718055922117	1.65197043344997	1.3657619410465	1.44839004157782	1.15612725722875	1.20955957535627	1.14055633222276	0.0246257565691189	NA	NA	0.0272307338322238	0.0124632653804115	63.1642102459344
a358	loss_cnaOV59	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.77999942857892	5.05135908406078	0.728640344518145	0.557859954404289	0.534311869226448	1.35759728359638	1.30613487984852	1.36369859343203	0.0246499935522599	NA	NA	0.00680291246659266	0.0727651869888832	63.1642102459344
a359	loss_cnaOV84	1032	Afatinib	ERBB2, EGFR	6	25	-0.693147180559945	NA	1.71789871269522	0.0305031378744005	1.68739557482082	0.589884426464516	1.67443113395531	1.09370408311417	2.86055284580788	1.00774259424745	0.0246661446933703	NA	NA	0.822984402955769	0.000413458849711247	63.1642102459344
a360	TP53_mut	172	Embelin	XIAP	12	7	3.46573590279973	NA	2.72562029191797	3.73631607847239	-1.01069578655442	0.76998526187109	0.909344848357502	1.22974585622062	1.31261705464128	1.11145489896378	0.0247465877880099	NA	NA	0.621614661155809	0.0311317910301777	63.1642102459344
a361	loss_cnaOV83	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	3.96560171729592	1.68566243449544	2.27993928280048	2.91890655021984	1.5748966503942	1.25781355873089	0.781093619673695	1.44767549174087	0.0247518890297775	NA	NA	0.103601890083414	0.156955810463226	63.1642102459344
a362	loss_cnaOV84	1494	SN-38	TOP1	6	26	-2.99573227355399	NA	-3.02224012487845	-4.45141496830545	1.429174843427	2.06881900927928	0.966466487198302	1.17015180118185	0.690816759231579	1.4787629600795	0.0247872831249225	NA	NA	0.181926586461879	0.154163786081001	63.1642102459344
a363	loss_cnaOV102	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	5.96312094507126	4.14236755526557	1.82075338980569	0.561062152300761	1.23726478205622	1.51081899564917	3.245190184972	1.47159558423684	0.0248637097448319	NA	NA	0.333547563072114	0.00815303906145509	63.1642102459344
a364	TP53_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	22	10	1.63315443905142	NA	2.68178534059807	3.26412770272941	-0.582342362131345	0.808160758211439	0.635309724924507	0.765794469993389	0.720577380446115	0.916627495668422	0.024923974332564	NA	NA	0.0118873510803403	0.0385816082653862	63.1642102459344
a365	loss_cnaOV102	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.87516842249659	5.06663954484578	0.808528877650813	0.628654305282243	0.532256941462041	1.49944200050827	1.28612636683974	1.51905746016179	0.0250188530527699	NA	NA	0.00682500549250972	0.147451529195317	63.1642102459344
a366	KRAS_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.6094379124341	NA	0.10181988546458	1.45488841986092	-1.35306853439634	1.08297178937591	1.4570200406069	0.971691790359194	1.24940330641123	0.928654717633627	0.0250465065200681	NA	NA	0.798059652602449	0.018298115874742	63.1642102459344
a367	loss_cnaOV20	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	6.01742207113208	5.0492137387473	0.968208332384784	0.561298941594842	0.645474266025701	1.53143289414414	1.72494238031836	1.49999524899143	0.0250872980808192	NA	NA	0.081724607493344	0.0289851284855619	63.1642102459344
a368	loss_cnaOV102	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	5.31673800095796	4.19060416592362	1.12613383503434	0.395129751799112	0.75003741886309	1.54030015136868	2.85003553872317	1.50143687063151	0.0251424191606027	NA	NA	0.187862916582965	0.0153284482966735	63.1642102459344
a369	loss_cnaOV52, loss_cnaOV53	206	Ruxolitinib	JAK1, JAK2, TYK2	8	24	1.65632149833295	0.0237165266173161	4.84959374669968	4.31938086901802	0.530212877681659	0.289048898477395	0.558397416007004	1.04275000812675	1.83433626792778	0.94952602301263	0.0252551751240716	NA	NA	0.326190360675461	0.00201959932848843	63.1642102459344
a370	TP53_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	22	10	2.30258509299405	NA	1.19327783956694	0.1563972346884	1.03688060487855	1.22963021646738	0.95620127380217	0.898181794715492	0.843245872614788	1.08437484166442	0.0252656288646511	NA	NA	0.831931375454117	0.0165960812374849	63.1642102459344
a371	loss_cnaOV87, loss_cnaOV88	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.68941315531623	4.32351298159173	1.3659001737245	0.87197778330502	0.905320348531805	1.51239731742928	1.56643919131447	1.50874789895051	0.0252707610812332	NA	NA	0.0203254356118259	0.100108904071344	63.1642102459344
a372	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	3.51600861844236	1.21003114352569	2.30597747491667	2.43012873603269	1.59059932556357	1.38733162124377	0.948911652590593	1.44975383671789	0.0254125484566117	NA	NA	0.584056975660082	0.238665667584461	63.1642102459344
a373	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.87975634543298	3.73753811708826	1.14221822834471	0.888914318197502	0.796908149130424	1.42215146292172	1.28495874682371	1.433312270167	0.025420906179193	NA	NA	0.91754015063866	0.147107021067745	63.1642102459344
a374	ARID1A_mut	258	STF-62247	stimulates autophagy	8	23	2.32630161961136	NA	3.90797306760457	4.69175594191134	-0.783782874306766	0.674236076220567	0.550641258046106	1.34467526041282	1.16247543249282	1.42340019541568	0.0254687058141986	NA	NA	0.0367246042752463	0.0136115065146231	63.1642102459344
a375	gain_cnaOV48_(SOX17)	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	1.5030129063464	2.99581264065161	-1.49279973430521	0.260577103072807	1.01558395375126	1.51791910225008	5.72882159138945	1.46989298993083	0.0255756548757414	NA	NA	0.268520308681827	6.21601042619051e-05	63.1642102459344
a376	NF1_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	-1.84666299714086	0.092427884123216	-1.93909088126407	2.09768030701799	1.38684869501408	1.31344407463229	0.92439771435936	1.39819930482351	0.0255905966919598	NA	NA	0.075351621560675	0.160195885016461	63.1642102459344
a377	loss_cnaOV20	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	5.5087308385252	4.35310842408379	1.15562241444141	0.634980539440562	0.966883114814995	1.24327004226688	1.81993359270435	1.1952038428787	0.0256034550322698	NA	NA	0.157582110132821	0.0094002914558637	63.1642102459344
a378	TP53_mut	1072	BMS-708163	g-secretase	23	10	1.6094379124341	NA	4.06076217075669	3.33678826215431	0.723973908602379	0.793852089911422	0.819065417228361	0.903551265446832	0.911975817413493	0.883902425098397	0.0256718329711282	NA	NA	0.91756379688592	0.0310090047411823	63.1642102459344
a379	loss_cnaOV42	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	0.834502717569985	-1.32997835251349	2.16448107008347	1.44711467975836	1.88631066075412	1.17182895240305	1.49572186666291	1.14746797286198	0.0257860005999524	NA	NA	0.406595682753648	0.0475126157710139	63.1642102459344
a380	loss_cnaOV87, loss_cnaOV88	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	3.75687854846195	1.50563304135965	2.2512455071023	0.455087888808216	1.50628696204305	1.54372154377084	4.94683678134758	1.49456615096025	0.0258273318043332	NA	NA	0.027442654928257	0.000307608275653194	63.1642102459344
a381	loss_cnaOV44	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	0.43508376914959	-0.857940038307494	1.29302380745708	1.66646869123372	0.760294064701706	1.52392508134222	0.775906450723557	1.70068907214788	0.0258908664791228	NA	NA	0.028756810814667	0.310343149141856	63.1642102459344
a382	BRCA1_mut	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	3.91192516645385	2.059637017801	1.85228814865285	1.90874943176291	1.66937356069336	1.09342888978187	0.970419751188652	1.10957079485763	0.0260493907319224	NA	NA	0.0856508449468714	0.14521898136962	63.1642102459344
a383	loss_cnaOV87, loss_cnaOV88	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	5.4476481407241	3.94295744477769	1.50469069594641	0.908758853146683	1.04314074898865	1.45419372607121	1.65576455264919	1.4424618129483	0.026104934431432	NA	NA	0.804831788284752	0.0875719687878685	63.1642102459344
a384	gain_cnaOV95_(MECOM)	164	JQ12	HDAC	5	14	1.63315443905142	NA	3.67812232555669	1.1209540331472	2.55716829240949	1.82122341729913	1.9265443276673	1.34425955330837	1.40409368126936	1.32733426149907	0.0261857683754406	NA	NA	0.610912827090201	0.0308975102911119	63.1642102459344
a385	gain_cnaOV18_(CCNE1)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	4.79430866442546	3.34982181325513	1.44448685117033	1.84453153634679	0.945558918184075	1.39835926548505	0.783118544034886	1.52765398685514	0.0262139790502688	NA	NA	0.704212808781641	0.306718474339138	63.1642102459344
a386	loss_cnaOV40	1009	ATRA	Retinoic acid and retinoid X receptor agonist	7	24	2.30258509299405	NA	5.11527769933294	4.33561103382201	0.779666665510931	1.16254737101276	0.770762059381216	0.899809938061211	0.670653673950265	1.0115529896955	0.0264021836881368	NA	NA	0.493635785273504	0.135324908709105	63.1642102459344
a387	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	330	XMD13-2	RIPK	7	25	2.32630161961136	NA	4.90323691454048	3.85464207675768	1.04859483778281	0.99414044420226	1.04745968372146	1.01116633757717	1.05477535281672	1.0010837210052	0.0265544670416033	NA	NA	0.804930586748347	0.0348530308867577	63.1642102459344
a388	KRAS_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	7	26	1.6094379124341	NA	1.12516280267386	2.67203249235748	-1.54686968968362	1.14207030752855	1.48288548735023	1.08681557906929	1.35444348696103	1.04314844462314	0.0265849172126902	NA	NA	0.207281202866441	0.0115792040855483	63.1642102459344
a389	BRCA1_mut	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	1.15476729108219	-0.298876201978718	1.4536434930609	0.788083273514448	1.20218774698713	1.24649113577274	1.84453032048047	1.20916512142464	0.0267432689974599	NA	NA	0.747769953014924	0.0222953165132738	63.1642102459344
a390	BRCA1_mut	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.77869653424956	4.82165843037905	0.957038103870516	0.161396724273164	0.79795929109113	1.2592170777074	5.9297244611404	1.19935705311716	0.0268350221228213	NA	NA	0.941666057246236	5.87977241562599e-06	63.1642102459344
a391	loss_cnaOV87, loss_cnaOV88	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	4.53169969750789	1.78433776639079	2.7473619311171	3.16020164010981	1.69033558031974	1.50497036791744	0.869362858447739	1.62533520746065	0.0268415023318064	NA	NA	0.104414138524738	0.269321054547276	63.1642102459344
a392	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.99152154460553	0.661425077567745	1.33009646703779	2.09484338336325	0.927259042465073	1.15321681950701	0.634938381361156	1.43443892820047	0.0268778413118639	NA	NA	0.83224128256864	0.230931939104779	63.1642102459344
a393	TP53_mut	1007	Docetaxel	Microtubules	21	10	-4.38202663467388	NA	-4.31042068974386	-5.35869900651655	1.04827831677269	1.46190581337343	1.02033971263986	0.781990879455043	0.717062827976399	1.02738166885669	0.0268866490962493	NA	NA	0.106173249179002	0.0295493669614965	63.1642102459344
a394	gain_cnaOV48_(SOX17)	293	MP470	PDGFR	3	29	2.99573227355399	NA	1.88403468282491	4.27322976665083	-2.38919508382593	2.23451568165009	1.57770446053675	1.46599047537542	1.0692227865958	1.51434894404311	0.0269167647770864	NA	NA	0.593821652945927	0.200472067692854	63.1642102459344
a395	loss_cnaOV40	274	PXD101, Belinostat	HDAC	7	23	2.99573227355399	NA	-0.720500821291993	1.3341895143359	-2.05469033562789	0.66750367785966	2.10512574487922	1.08633016277294	3.07817080831108	0.976041616813619	0.0270275901593791	NA	NA	0.376191779184089	0.000362935831881579	63.1642102459344
a396	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	3.94104110001013	1.69021069695577	2.25083040305436	2.79349486104108	1.61614196452932	1.2382646199265	0.805739947635169	1.39271824657426	0.0270848628237036	NA	NA	0.104504638682355	0.147185199161634	63.1642102459344
a397	loss_cnaOV85	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	5.05685650541048	3.54316900201738	1.5136875033931	1.3291381004986	1.49795301046714	1.03349968949641	1.1388489298631	1.01050399633101	0.0270977721792561	NA	NA	0.692492539525163	0.0260741440963132	63.1642102459344
a398	NF1_mut	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	0.454453370298236	2.0998468875048	-1.64539351720657	1.47735589663516	1.25226192525202	1.28971358886233	1.11374213955766	1.31393719159466	0.0271772635797972	NA	NA	0.0230931968037091	0.108030665755587	63.1642102459344
a399	TP53_mut	1241	CHIR-99021	GSK3B	22	10	2.30258509299405	NA	3.95151965666855	3.08730260814542	0.864217048523135	1.05156503508727	0.778711570424035	0.883895120653604	0.821838896965048	1.10980378531237	0.0273037448216085	NA	NA	0.817321949869763	0.0161054635783939	63.1642102459344
a400	ARID1A_mut	1036	PLX4720	BRAF	9	24	2.30258509299405	NA	3.49135389644024	4.61409185105078	-1.12273795461054	1.23451260591384	1.20905638313601	0.92354973685778	0.909458477161067	0.92860677985788	0.0273681685186193	NA	NA	0.334884857978705	0.03444997752757	63.1642102459344
a401	loss_cnaOV102	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.99303447634004	4.79500498607768	1.19802949026236	0.487578912141464	0.804049866674229	1.52358225452962	2.45709865711906	1.48999401643799	0.0274238068734878	NA	NA	0.123238219019465	0.0279606473763213	63.1642102459344
a402	BRCA1_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-0.834453896933971	-2.50015813696551	1.66570424003154	1.18861075457687	1.56120881182998	1.08931924887361	1.40138748839144	1.06693238432281	0.0275262518091596	NA	NA	0.098287008474784	0.057783542068859	63.1642102459344
a403	loss_cnaOV16, loss_cnaOV17	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	3.43764085211473	2.25939931691686	1.17824153519786	0.937957655791971	0.700545121018709	1.60856276153485	1.25617774738776	1.6818924289766	0.0275411341019527	NA	NA	0.569131165111129	0.150963465471259	63.1642102459344
a404	loss_cnaOV102	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	6.47927862149995	5.6485980520059	0.830680569494052	0.716170586057364	0.54244255468853	1.49479152649496	1.15989205039414	1.53137057982302	0.0275997534624332	NA	NA	0.159425612464278	0.176181841562997	63.1642102459344
a405	loss_cnaOV42	1248	FK866	NAMPT	4	28	0	NA	1.30234456333871	-2.13845807960529	3.440802642944	2.24547611134415	2.54857706458167	1.36544766828777	1.53232654115582	1.35008773749158	0.0276299245868948	NA	NA	0.0307078879863694	0.0455155465295013	63.1642102459344
a406	PIK3CA_mut	238	CAL-101	PI3Kdelta	6	26	2.99573227355399	2.32630161961136	3.59516180646134	4.57000521590162	-0.974843409440282	0.653420476491516	0.955980527772945	1.06826652120195	1.49190826506481	1.019731449668	0.0276523305204225	NA	NA	0.477803034168127	0.0127267742846932	63.1642102459344
a407	BRCA1_mut	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.69851823810282	4.79426555876977	0.90425267933305	0.213979531341109	0.85110711113527	1.1179951975392	4.22588400706216	1.06244286706392	0.027661947988307	NA	NA	0.123335598870569	0.000154928802430923	63.1642102459344
a408	loss_cnaOV41	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.97155286278843	4.35570838948473	0.615844473303704	0.531295995011255	0.508166086239687	1.2044431619697	1.15913629894887	1.21189605127098	0.0277965934912678	NA	NA	0.32757206206575	0.057745604452027	63.1642102459344
a409	KRAS_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	7	24	2.30258509299405	NA	0.307433020278495	1.73032261818745	-1.42288959790896	0.700039036261728	1.46785750915291	1.05756246542254	2.03258607620986	0.969364934291267	0.0278320070887955	NA	NA	0.4402544930936	0.00176581462316946	63.1642102459344
a410	loss_cnaOV82	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-0.585761266192313	-2.95422659013793	2.36846532394562	1.25689277940041	1.65823991974509	1.4489994861641	1.88438135914463	1.42830075174508	0.027878829872838	NA	NA	0.672932584742373	0.0633355982776623	63.1642102459344
a411	loss_cnaOV43_(NF1)	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	5.39440126768248	4.27696702198876	1.11743424569373	0.785015544359096	0.915868147681363	1.24225392266361	1.42345492866135	1.22008200473251	0.0278847875796933	NA	NA	0.0206684520878552	0.028302932567809	63.1642102459344
a412	loss_cnaOV83	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	-0.0684767093825058	1.54854582377145	-1.61702253315396	1.46557376964331	1.21461397697223	1.30097911034417	1.1033375232606	1.33130571836893	0.0279217103803488	NA	NA	0.54944067619539	0.110280386438768	63.1642102459344
a413	TP53_mut	1170	CCT018159	HSP90	23	10	2.30258509299405	NA	3.97442746999496	3.05218193278058	0.922245537214384	1.19612504678771	1.04447222776466	0.799068037641412	0.771027694546778	0.882977558137793	0.0279321825815952	NA	NA	0.166070826265292	0.0377550688894345	63.1642102459344
a414	gain_cnaOV72_(ASXL1)	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	1.22794647858337	0.112048644993683	1.11589783358969	1.10434496363592	1.06629418739068	1.04164917241682	1.01046128730984	1.04651966294629	0.0279707811002205	NA	NA	0.118622726976844	0.0863390013850398	63.1642102459344
a415	loss_cnaOV33_(ZFHX3)	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.70723172142381	3.72194778149144	0.985283939932375	0.881288570965712	0.79760489772702	1.22231063408546	1.11800376447944	1.23530327200873	0.0281091861454287	NA	NA	0.91778140395506	0.106769721457774	63.1642102459344
a416	loss_cnaOV58	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	5.29474317546696	4.21916261388428	1.07558056158268	0.662181877107661	0.940142575498745	1.18454598653001	1.6242977930485	1.14406111329666	0.0281679250437892	NA	NA	0.478046704485347	0.0162079883351364	63.1642102459344
a417	loss_cnaOV21, loss_cnaOV22	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	4.94578642414964	3.5506585950246	1.39512782912504	0.545412375187084	0.998698425771501	1.43081608787652	2.55793211264504	1.39694605811289	0.0282101674922641	NA	NA	0.817498908873867	0.0228576036558674	63.1642102459344
a418	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1025	SB 216763	GSK3A, GSK3B	5	18	2.30258509299405	NA	5.69470638036085	4.75585877036007	0.938847610000781	0.692511337847319	0.738565944487482	1.2860614770807	1.35571442471859	1.271176415604	0.0282133819402504	NA	NA	0.40225318508556	0.034332970441915	63.1642102459344
a419	loss_cnaOV102	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	3.313558913211	2.18474548853892	1.12881342467208	0.627653058909407	0.853820296884376	1.34353852780431	1.79846717648995	1.32207377687221	0.0282980799358601	NA	NA	0.563908388524262	0.0690186075817785	63.1642102459344
a420	loss_cnaOV87, loss_cnaOV88	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	5.22539692756178	3.54191534516682	1.68348158239496	0.18975391746771	1.165903707993	1.49152732416871	8.87192003654645	1.44392849156722	0.0284270323906007	NA	NA	0.166281124649733	3.63980418102009e-07	63.1642102459344
a421	BRCA1_mut	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	0.0438412152068829	-0.848562575951848	0.892403791158731	0.989093809597	0.868969521102841	1.0125874700771	0.902243834204498	1.02696788493358	0.0285472548271914	NA	NA	0.0291801233298923	0.167837920935022	63.1642102459344
a422	loss_cnaOV87, loss_cnaOV88	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	5.37120791454291	4.16484359234381	1.2063643221991	1.15485235019675	0.798455004867706	1.45871108072868	1.0446048120295	1.51087326755373	0.0286028975568488	NA	NA	0.488735595505995	0.20772452187455	63.1642102459344
a423	gain_cnaOV48_(SOX17)	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	2.72927526838459	4.01834619885859	-1.289070930474	0.556874627316335	1.03784311620427	1.27162075322386	2.31483150289362	1.24206723573843	0.0286289694581491	NA	NA	0.280834643024876	0.0306752350945559	63.1642102459344
a424	loss_cnaOV38	1047	Nutlin-3a	MDM2	8	25	2.07944154167984	1.38629436111989	4.88900347405435	3.38248356824708	1.50651990580728	0.79871014342539	1.56121495904939	1.05709275172827	1.88619102713074	0.964966353335859	0.02873783109612	NA	NA	0.135699091429949	0.00151092255263039	63.1642102459344
a425	loss_cnaOV41	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.22795746676995	0.530937801117316	0.697019665652631	0.575295848904816	0.563145389562951	1.23414246571133	1.21158472980387	1.23772595598017	0.0287456437371362	NA	NA	0.00918677317064002	0.050185483119279	63.1642102459344
a426	loss_cnaOV102	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	4.51710973998298	2.86354607656101	1.65356366342197	0.793441648964541	1.11014436974879	1.5152825642348	2.0840394067792	1.48950326505385	0.0288032515448285	NA	NA	0.0661582810561754	0.048261261579881	63.1642102459344
a427	loss_cnaOV58	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	3.06595549849534	1.42761800034206	1.63833749815328	0.584454342264334	1.44758222595268	1.20075809498332	2.80319159201712	1.1317750859196	0.0288447430850813	NA	NA	0.289670387457683	0.000625860354817908	63.1642102459344
a428	loss_cnaOV83	1030	KU-55933	ATM	5	28	2.30258509299405	NA	5.09946656144123	3.98162477750382	1.11784178393741	0.808474873750997	0.97181741534533	1.17381323409858	1.38265494727261	1.15025905719151	0.0288567378669045	NA	NA	0.498448810680361	0.031555182701428	63.1642102459344
a429	loss_cnaOV43_(NF1)	304	SB52334	ALK5	5	27	2.99573227355399	NA	5.21887019122684	4.20882015880174	1.0100500324251	0.829939643109669	1.02591127960104	1.0080352690683	1.21701625029091	0.984539357845739	0.0289278641242085	NA	NA	0.315052621612465	0.0499381385985463	63.1642102459344
a430	loss_cnaOV36	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.53308623123512	4.52408958587481	-0.991003354639693	0.529350155926582	0.691069842753985	1.45418533929758	1.87211308723434	1.43401331288085	0.0290469552975347	NA	NA	0.491863093942347	0.0645505900335515	63.1642102459344
a431	loss_cnaOV87, loss_cnaOV88	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	0.999256122596042	-1.55705303893949	2.55630916153553	1.14198386362288	1.75745638308145	1.48339980152536	2.23848098293245	1.45455055735347	0.0290611680313398	NA	NA	0.05478458509745	0.0384550018107588	63.1642102459344
a432	loss_cnaOV85	1030	KU-55933	ATM	7	26	2.30258509299405	NA	4.92460766104969	3.94271434422943	0.981893316820254	0.97973639387321	0.945278395934626	1.03135176609882	1.00220153396417	1.03873453687622	0.0292720866317898	NA	NA	0.498626390800282	0.0411365213216119	63.1642102459344
a433	loss_cnaOV102	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-2.87858127231777	-4.83821716902976	1.95963589671199	1.65009753937203	1.27229761557724	1.50523845357763	1.18758791523183	1.5402338829527	0.0295063912911112	NA	NA	0.107146566214421	0.169281460488323	63.1642102459344
a434	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	272	AR-42	HDAC	3	27	1.63315443905142	NA	2.3425103670572	0.0676074869095204	2.27490288014768	2.29485654942071	1.66787519187304	1.32242214588014	0.991305047246606	1.36395270535378	0.0295483111314487	NA	NA	0.449725423713609	0.223590189624627	63.1642102459344
a435	ARID1A_mut	1010	Gefitinib	EGFR	8	22	-0.693147180559945	NA	0.281455280922128	1.15959717762433	-0.8781418967022	1.09583449112362	1.2535947786249	0.722111674743514	0.801345370870556	0.700499006278137	0.0295652368402213	NA	NA	0.953821462067397	0.0829110661336973	63.1642102459344
a436	loss_cnaOV59	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	0.67677808638544	-1.60228150382139	2.27905959020683	1.36918098216628	1.75386803516717	1.32559184979008	1.66454224817012	1.29944758927635	0.0295987825683109	NA	NA	0.0549104000225882	0.0340967489131999	63.1642102459344
a437	loss_cnaOV44	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.85345011705575	3.74016873992599	1.11328137712976	0.922993164915837	0.798086525746669	1.37999452946763	1.20616427016691	1.39493819431195	0.0297186582929544	NA	NA	0.917914310956872	0.164102622796475	63.1642102459344
a438	loss_cnaOV81_(RB1)	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	3.62530965844778	2.38693907126299	1.23837058718479	0.742600463849484	0.976923440530492	1.29433982318715	1.66761353846366	1.26762296389605	0.0297404109854339	NA	NA	0.360349913846824	0.0337867178642539	63.1642102459344
a439	PIK3R1_mut	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	3.03972288039322	1.12424167200309	1.91548120839013	2.35521214029989	1.50937740344559	1.15949530013328	0.813294554496577	1.26905385228207	0.0297533535591999	NA	NA	0.585902535221094	0.14475326855004	63.1642102459344
a440	loss_cnaOV59	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.93541089689462	1.18289371818036	1.75251717871426	2.69370129171004	1.0919321991081	1.29919624183214	0.650598187745497	1.60496886175326	0.0297598001653663	NA	NA	0.44120184598868	0.284989792968793	63.1642102459344
a441	PIK3CA_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	7	26	2.30258509299405	NA	1.84649641125801	2.87281354939945	-1.02631713814145	1.96362537097939	1.58032082382689	0.617733156961225	0.522664431469204	0.649435938998847	0.0299147620563634	NA	NA	0.614763494143128	0.23683157448397	63.1642102459344
a442	loss_cnaOV42	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	4.3727743834754	2.60552685686106	1.76724752661433	1.01959698411692	1.49521584452144	1.21377361684997	1.73328045702779	1.18193472406652	0.029915674638102	NA	NA	0.966426173994685	0.0286339268564419	63.1642102459344
a443	loss_cnaOV83	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	4.43433012685752	3.40532674793081	1.02900337892671	1.44116796388054	0.712367750448415	1.22121644833595	0.714006559066145	1.44448338414952	0.0299328233572976	NA	NA	0.115778200661685	0.187350346806681	63.1642102459344
a444	SMARCA4_mut	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	3.23878067002406	4.66762895285573	-1.42884828283167	0.762277074902609	0.94189153209389	1.53475243468389	1.8744474022313	1.51699875638041	0.030050935639834	NA	NA	0.159529976984221	0.0657893969055526	63.1642102459344
a445	gain_cnaOV49	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.09037703287774	5.79227752669095	-0.701900493813212	0.209954543395545	0.588977845054075	1.22799366684413	3.34310695287439	1.19172647953977	0.030120165855758	NA	NA	0.160490487647195	0.00458208108363178	63.1642102459344
a446	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	3.42404608020668	2.26194833664962	1.16209774355705	0.960018922087458	0.701101875687062	1.57828615910696	1.21049462340825	1.65753050142424	0.0302236821956375	NA	NA	0.571097303222217	0.16118786399714	63.1642102459344
a447	ARID1A_mut	1030	KU-55933	ATM	9	24	2.30258509299405	NA	3.56795137935984	4.36963600679477	-0.801684627434937	0.953725813917708	0.976502709693354	0.825903446367108	0.840581869270983	0.820975322932474	0.0302646474107488	NA	NA	0.499040191448993	0.0498388339680923	63.1642102459344
a448	loss_cnaOV16, loss_cnaOV17	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	5.6411211140918	3.63686878307976	2.00425233101203	1.097285074809	1.40264642678757	1.46268233085226	1.82655572104716	1.42890773664344	0.0303197183339137	NA	NA	0.70642280383936	0.0611022354529902	63.1642102459344
a449	TP53_mut	1058	GDC0941	PI3K (class 1)	23	10	1.38629436111989	0.693147180559945	1.14341770475104	0.154913879456582	0.988503825294453	1.30230789897299	1.19826008591486	0.776529285206675	0.759040028916355	0.824949305175045	0.0303781056574214	NA	NA	0.134587461185559	0.0476430100654612	63.1642102459344
a450	loss_cnaOV102	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	6.73658283652236	5.41483162245253	1.32175121406984	0.451511557355179	0.928887488588346	1.46060943541754	2.92739176337427	1.42294005496676	0.0303838513464056	NA	NA	0.268369463116269	0.0128414592465694	63.1642102459344
a451	PIK3CA_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	7	26	0.693147180559945	NA	1.21068724506556	1.87970031905512	-0.669013073989556	2.52433447441568	1.42056040456553	0.395543565455991	0.265025526834916	0.470950106619485	0.0306411715593564	NA	NA	0.196732641152811	0.522324923062132	63.1642102459344
a452	loss_cnaOV102	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.90135561580389	3.8845166557033	1.01683896010059	0.69664308742268	0.704690281875941	1.44405217333317	1.45962685693547	1.44295868164051	0.0306450543270206	NA	NA	0.493830353839331	0.115059194674094	63.1642102459344
a453	gain_cnaOV51_(MYC)	223	ZSTK474	PI3K	8	24	1.63315443905142	2.32630161961136	0.107807516706434	0.975083355754281	-0.867275839047847	1.12857177398764	0.933947868611728	0.882441976572881	0.768472027245069	0.928612686205938	0.0306575868597464	NA	NA	0.754604413451042	0.0771805976921962	63.1642102459344
a454	loss_cnaOV40	1010	Gefitinib	EGFR	7	23	-0.693147180559945	NA	1.81000393534265	0.656206635117988	1.15379730022466	0.700126245618181	1.27646574048032	0.9803134433386	1.64798464197825	0.903899935293598	0.0307729932700137	NA	NA	0.953881265446685	0.00624940214921568	63.1642102459344
a455	NF1_mut	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	0.318917841593333	1.74816505269632	-1.42924721110299	1.13830417654177	0.924897673042322	1.5103705903897	1.25559339986357	1.54530306731303	0.0308353619257402	NA	NA	0.2385134979134	0.151854089460502	63.1642102459344
a456	PIK3R1_mut	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	1.96887622130684	3.16823022009215	-1.19935399878531	0.527176026733398	0.956106311887526	1.31484263941696	2.27505413365817	1.25441489494779	0.0308445961036919	NA	NA	0.0672761455224034	0.00258107329762581	63.1642102459344
a457	PIK3R1_mut	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	0.774504356171702	-1.39903351040579	2.17353786657749	2.83233880597702	1.60205765569124	1.19758315348885	0.767400376674824	1.35671638212026	0.0308856885299253	NA	NA	0.409121856001855	0.163007978291616	63.1642102459344
a458	loss_cnaOV41	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-2.57866970471108	-4.2791956293324	1.70052592462132	1.41079373373152	1.42108373340968	1.19753431717407	1.20536821504265	1.19664020116616	0.0308902719267174	NA	NA	0.853172292747192	0.0885554886055667	63.1642102459344
a459	loss_cnaOV42	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-2.57866970471108	-4.2791956293324	1.70052592462132	1.41079373373152	1.42108373340968	1.19753431717407	1.20536821504265	1.19664020116616	0.0308902719267174	NA	NA	0.853172292747192	0.0885554886055667	63.1642102459344
a460	loss_cnaOV82	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	3.18320574796347	1.21893416909136	1.96427157887211	2.39810673212962	1.23994644247544	1.45280563452596	0.81909264193915	1.58415840522162	0.0311179670055793	NA	NA	0.441831237819143	0.290413021027819	63.1642102459344
a461	SMAD4_mut	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.10131908166051	-3.92670106509829	1.82538198343778	1.87315945156405	1.59359727275856	1.12348502703992	0.974493645969979	1.1454474820216	0.0311415123495482	NA	NA	0.209958086173797	0.143977246338066	63.1642102459344
a462	gain_cnaOV72_(ASXL1)	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	5.02724620955555	3.51921021252978	1.50803599702577	0.741369565847864	1.55004924240514	1.0252457049066	2.03412180172396	0.97289554148991	0.031144642511845	NA	NA	0.136582926993225	0.00540924966096685	63.1642102459344
a463	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	2.25571537278904	1.49572587065469	0.759989502134358	0.705005925481365	0.614903691816575	1.21082010400807	1.07799023336641	1.23594883597001	0.0311619205545768	NA	NA	0.176642493275803	0.0717033446774685	63.1642102459344
a464	loss_cnaOV44	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.65212042492607	4.32737085025278	1.32474957467329	0.928207047114067	0.907262700743593	1.45789310648143	1.42721344207861	1.46016095843853	0.0311970397284645	NA	NA	0.0210630901119062	0.1205971570466	63.1642102459344
a465	gain_cnaOV4_(KRAS)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.6094379124341	NA	2.2374679883	0.879906238328307	1.35756174997169	1.46047034711119	1.37469471589553	0.975463729608669	0.929537359424617	0.987536894027645	0.0312407786799149	NA	NA	0.799329447993302	0.0542045305932684	63.1642102459344
a466	PIK3CA_mut	1036	PLX4720	BRAF	7	26	2.30258509299405	NA	3.32705859925446	4.57196074224614	-1.24490214299168	1.17482600051218	1.2204295092236	1.02736993896081	1.05964810316503	1.02005247626604	0.031288187090106	NA	NA	0.336741274354027	0.0336876771737873	63.1642102459344
a467	loss_cnaOV83	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	5.38371820607855	4.6860619007979	0.69765630528065	0.31873265159798	0.650314612091817	1.13164878563643	2.18884479447876	1.07279813848339	0.0313729091569283	NA	NA	0.74424759918588	0.00338801533272356	63.1642102459344
a468	loss_cnaOV43_(NF1)	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.94401160690007	2.81552747266478	1.12848413423529	0.536872585410491	0.9687788800389	1.22069796620208	2.10195894687462	1.16485212207555	0.0314029761137724	NA	NA	0.06741122025693	0.00420209574016662	63.1642102459344
a469	PIK3R1_mut	272	AR-42	HDAC	5	25	1.63315443905142	NA	1.97610550739521	-0.0411037715698968	2.01720927896511	2.35925233846689	1.5493778086463	1.1943080760539	0.855020569896287	1.3019479611158	0.0314082762081714	NA	NA	0.450611687659402	0.129584162998225	63.1642102459344
a470	loss_cnaOV58	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.68576452629206	0.586505112603477	1.09925941368859	0.524279774272826	1.02457080967173	1.12994233475863	2.09670383568249	1.0728974545359	0.0314505106765542	NA	NA	0.754786566740614	0.0043641573373406	63.1642102459344
a471	KRAS_mut	1061	SB590885	BRAF	7	26	1.6094379124341	NA	3.07744983106541	4.15641020703836	-1.07896037597295	1.19525325857445	1.21509184866115	0.890762351245588	0.90270440028735	0.887966104917748	0.0314865121957481	NA	NA	0.544915660657323	0.0618502682146488	63.1642102459344
a472	loss_cnaOV1	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	4.10811435676756	0.998352713817916	3.10976164294965	2.07698031633726	2.15685863363391	1.4453079278435	1.49725137907599	1.44180132830971	0.0315535580421729	NA	NA	0.328003602843672	0.109168836984865	63.1642102459344
a473	loss_cnaOV40	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	0.131169326678498	1.81294635780404	-1.68177703112554	0.824856644423015	1.80722851357317	1.01765177522691	2.03887189670629	0.930583497601202	0.0315741849367491	NA	NA	0.586592971392939	0.00202700352537877	63.1642102459344
a474	loss_cnaOV16, loss_cnaOV17	221	TAK-715	p38a	6	26	2.99573227355399	2.32630161961136	5.00474598775002	4.11021584596535	0.894530141784679	0.875438495601097	0.818339675958495	1.08018135674524	1.02180809534823	1.09310371727601	0.0316029984949122	NA	NA	0.49003037503565	0.0555377489310544	63.1642102459344
a475	loss_cnaOV87, loss_cnaOV88	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	5.43153302421558	4.10910360714982	1.32242941706576	0.976995802870336	0.899773474413248	1.46132154828136	1.35356714243866	1.46973594429213	0.0316210730486933	NA	NA	0.178355744796786	0.134013516464243	63.1642102459344
a476	loss_cnaOV40	272	AR-42	HDAC	7	23	1.63315443905142	NA	-1.05841590885843	0.707036722162507	-1.76545263102094	0.818185305530609	1.85973132707641	1.04376605238496	2.15776624083465	0.94930520625058	0.0317203756474617	NA	NA	0.450754958263612	0.0016113496290453	63.1966457078108
a477	gain_cnaOV94	344	THZ-2-49	CDK9	7	25	2.99573227355399	NA	4.33480328614635	2.09791602131734	2.23688726482901	1.33964017921784	2.30991191320523	1.03985251541541	1.66976722520747	0.968386392589795	0.0317719521611908	NA	NA	0.350800227762149	0.0045286396191051	63.1966457078108
a478	loss_cnaOV52, loss_cnaOV53	1021	Axitinib	PDGFR, KIT, VEGFR	8	22	0.693147180559945	NA	3.26221142689441	2.25730433554709	1.00490709134732	0.724100923505097	1.00334554740301	1.0675365799238	1.38779976482139	1.00155633714462	0.0318643782473552	NA	NA	0.162098004029416	0.00770972769654089	63.1966457078108
a479	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.84988398565821	5.06925517624286	0.780628809415354	0.661444241930432	0.533461306027347	1.43779979175878	1.18018838161941	1.46332789387978	0.0320079935576997	NA	NA	0.00719797599680299	0.170681453053063	63.1966457078108
a480	gain_cnaOV49	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.21049734013631	5.83361495089912	-0.623117610762812	0.244334292072046	0.552096824017435	1.16129933358699	2.55026670828128	1.12863828164883	0.03203792402671	NA	NA	0.0860729086945457	0.0182660800834132	63.1966457078108
a481	loss_cnaOV43_(NF1)	134	Etoposide	TOP2	3	16	2.77258872223978	NA	4.14385260384088	1.93445920394759	2.20939339989328	2.50447347515873	1.49495006602742	1.34214135035015	0.88217879798198	1.47790447995656	0.0320601252776147	NA	NA	0.345644491866851	0.262600786072498	63.1966457078108
a482	TP53_mut	1043	JNK Inhibitor VIII	JNK	23	10	2.30258509299405	NA	4.67466352767286	3.90699321054244	0.767670317130415	0.862843468079468	1.13675518817459	0.807621139198131	0.88969824253188	0.675317188006984	0.032148413392697	NA	NA	0.340988010170542	0.0773017014172213	63.1966457078108
a483	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	5.49496709764368	3.59635740754737	1.89860969009631	1.11708881955806	1.63264529658732	1.20805796542696	1.69960495249378	1.1629039657695	0.032220173510463	NA	NA	0.118741789473638	0.0131530865170751	63.1966457078108
a484	loss_cnaOV57_(ZNRF3)	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	4.53289936523489	3.42721386604864	1.10568549918625	1.45074941067704	0.753329210221571	1.30645753866851	0.762147818947065	1.46773214709283	0.0322837692105042	NA	NA	0.116547814699146	0.225143811939565	63.1966457078108
a485	loss_cnaOV40	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	3.55729732181516	2.12671136120378	1.43058596061138	1.77244541272448	1.20431734653141	1.06968353270289	0.807125539856477	1.18788122145018	0.0323551549950172	NA	NA	0.206774819439905	0.0811147990469539	63.1966457078108
a486	loss_cnaOV43_(NF1)	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	4.11859307460564	1.20699552343651	2.91159755116912	3.17050040522412	1.87261462997601	1.40791155203425	0.918340065931424	1.55483007798909	0.0323957507936518	NA	NA	0.563180686897098	0.248705696632608	63.1966457078108
a487	loss_cnaOV83	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.938593227809	2.81649504035962	1.12209818744938	0.399312312331449	0.979729326542696	1.21239587169371	2.81007660619786	1.14531448334723	0.0326189981322109	NA	NA	0.0676974501187351	0.000582881074479889	63.1966457078108
a488	gain_cnaOV18_(CCNE1)	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	6.20742885332362	5.64473692528268	0.56269192804094	0.320862633951701	0.453389215830473	1.27326434704949	1.75368481244108	1.24107920610828	0.0326194799966822	NA	NA	0.346878105400882	0.027695059129834	63.1966457078108
a489	gain_cnaOV72_(ASXL1)	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	5.04240623591134	4.39103545770762	0.651370778203726	0.345563209319499	0.698332417779633	0.981809393666969	1.88495407102637	0.93275174060339	0.0326671668767623	NA	NA	0.0623498847829948	0.00829739621879176	63.1966457078108
a490	SMAD4_mut	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	1.11179219096407	-0.292509520479738	1.40430171144381	0.398264319958841	1.23187324697079	1.19675025486847	3.5260545348098	1.13997257014635	0.0328126106616969	NA	NA	0.749319962209274	0.000447874483689868	63.1966457078108
a491	gain_cnaOV96	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	2.45834220741775	3.58613478199542	-1.12779257457767	1.2854678524924	1.13539524267265	0.975151511803294	0.877340162487131	0.99330394578976	0.0328193793876204	NA	NA	0.291821317472026	0.123661287718948	63.1966457078108
a492	loss_cnaOV43_(NF1)	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	3.48248467055809	2.36821601241527	1.11426865814282	0.727333806589049	0.988531692411479	1.16210639496348	1.53199074214406	1.12719568497052	0.032977286746822	NA	NA	0.361771812876624	0.0209234100936859	63.1966457078108
a493	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	208	SB-715992	KIF11	7	25	-2.05572501506252	NA	-0.0953316749419756	-1.65957792147453	1.56424624653256	1.69320244289	1.78271667532842	0.886169620541151	0.923838878865935	0.877450841280982	0.0329969342426704	NA	NA	0.0556581151173644	0.058341929079915	63.1966457078108
a494	loss_cnaOV102	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.80187809419916	2.04665556063442	0.755222533564734	0.346623451055831	0.52692779160129	1.46022616311121	2.1787981490124	1.43325621764924	0.0330107515021492	NA	NA	0.0301189295868442	0.0419978990369827	63.1966457078108
a495	loss_cnaOV41	255	CP724714	ERBB2	5	27	2.32630161961136	NA	5.21294946701276	4.26731401175888	0.945635455253871	0.564017470278799	0.93031667156578	1.06223955812035	1.67660667458835	1.01646620355874	0.0330245202160518	NA	NA	0.770663660732885	0.0141679553962274	63.1966457078108
a496	loss_cnaOV87, loss_cnaOV88	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.81146954757913	4.98447372590725	0.826995821671878	0.180419609217699	0.588786594212673	1.44902368811801	4.58373579932769	1.40457651346111	0.0330548537134376	NA	NA	0.0870457005591693	0.00055819091183981	63.1966457078108
a497	SMAD4_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.74680743617789	2.66697779240864	1.07982964376924	1.04376364103003	0.882396284879428	1.20077283526848	1.0345538025291	1.22374681565754	0.0331026178161219	NA	NA	0.963715239498041	0.127072665143643	63.1966457078108
a498	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	5.06947260009531	2.61394698101431	2.45552561908101	0.694932410113687	1.76630861872327	1.43110581445785	3.53347402329285	1.39020191208483	0.0333691010196742	NA	NA	0.311596402409718	0.00423409206683428	63.2272098581606
a499	loss_cnaOV102	1028	VX-702	p38	3	28	0.693147180559945	NA	4.42994440703861	3.2087933089126	1.22115109812601	0.448586774777109	0.878368306394141	1.42710064847896	2.722218234661	1.39024949925511	0.0335018677604429	NA	NA	0.486045966760665	0.0171090468600587	63.2272098581606
a500	PTEN_mut	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	3.16761719061827	2.24643838130762	0.921178809310658	0.637786685882829	0.837296784432807	1.12402713066977	1.44433684443499	1.10018195033995	0.0335626220316792	NA	NA	0.581204235486279	0.0527444846554868	63.2272098581606
a501	loss_cnaOV82	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	5.41993529743673	4.11026337982771	1.30967191760903	0.935159394319777	0.904581279414685	1.44462091296384	1.40047988135933	1.44782116036766	0.0335948193346367	NA	NA	0.17909613729334	0.125314608401578	63.2272098581606
a502	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-2.60718577310921	-5.03789296466134	2.43070719155214	2.92847151742376	1.67361567012723	1.30292169436093	0.830025894767959	1.45236880541836	0.0336442575793426	NA	NA	0.287116757210543	0.284557524868017	63.2272098581606
a503	SMAD4_mut	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	5.0121451500948	3.67569560598272	1.33644954411208	0.774672115645668	0.970493433578379	1.39404610956191	1.72518090831007	1.37708252098559	0.0337079319977484	NA	NA	0.696925033907765	0.0783443360773357	63.2272098581606
a504	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	3.28367754668292	2.00511950577923	1.27855804090369	1.28060636693406	1.31924951382755	0.974995366764296	0.998400503009156	0.969155589979488	0.0338251776958838	NA	NA	0.498508887126148	0.0435388510085998	63.2272098581606
a505	loss_cnaOV102	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	2.7978869040724	1.15596102851443	1.64192587555797	0.716173023741377	1.14763150167175	1.46074664955257	2.29263854002814	1.43070826582067	0.0338989946154244	NA	NA	0.0758387922206963	0.035076691698396	63.2272098581606
a506	SMARCA4_mut	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	0.65940543088602	2.62381548241871	-1.96441005153269	1.737515284118	1.31368340897035	1.45933767080583	1.13058576778498	1.49534510226659	0.0339699394948004	NA	NA	0.207420538910599	0.183444998206123	63.2272098581606
a507	SMAD4_mut	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	1.93844872595704	3.38692434778597	-1.44847562182894	0.187513641696347	1.03948021402831	1.44069626414748	7.72464130462865	1.39346146495241	0.033984709332981	NA	NA	0.0460785479692611	2.08034747039082e-06	63.2272098581606
a508	gain_cnaOV48_(SOX17)	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	0.105235212855253	1.84688820217747	-1.74165298932222	2.47188849331505	1.29153226283374	1.24270685972582	0.704583962436949	1.34851682721489	0.0342034988899739	NA	NA	0.292095659605021	0.346199090754058	63.2272098581606
a509	SMARCA4_mut	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	3.32542659184701	4.40395895975694	-1.07853236790992	0.128171972623882	0.763830077765182	1.46184425281175	8.41472863240434	1.41200562704404	0.0342179691635978	NA	NA	0.192000593012133	1.03140130597949e-06	63.2272098581606
a510	loss_cnaOV42	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	5.02117995283491	4.37061325066751	0.650566702167402	0.599956880653483	0.50486526056511	1.26283198756189	1.08435576479895	1.2885947063167	0.0342642134155744	NA	NA	0.330567585339254	0.11464943631336	63.2272098581606
a511	gain_cnaOV48_(SOX17)	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	2.44376514522513	3.82007852340048	-1.37631337817535	0.733358317173801	1.18874438258707	1.1816385510503	1.87672703226351	1.15778749269887	0.0342763718910238	NA	NA	0.168518563972818	0.0587426728455177	63.2272098581606
a512	loss_cnaOV83	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.66024955977438	3.8538445208865	0.806405038887879	0.607762999482558	0.719649230974506	1.14261059864883	1.32684128447181	1.12055290852725	0.0343352839260233	NA	NA	0.495292558684769	0.0367381311226471	63.2272098581606
a513	loss_cnaOV54	286	KIN001-236	TIE2	10	22	2.32630161961136	NA	5.16270225291039	4.62796544649237	0.534736806418015	0.630127887411008	0.613962736473997	0.864072209140187	0.848616315991148	0.870959709198349	0.034434423354917	NA	NA	0.744935391545303	0.038453046537087	63.2272098581606
a514	KRAS_mut	1054	PD-0332991	CDK4, CDK6	7	26	1.38629436111989	0.693147180559945	0.908629424285322	2.65449108507874	-1.74586166079342	1.70953364542079	1.63310242960757	1.05927138760521	1.02125024884414	1.06904602500221	0.0345055482692199	NA	NA	0.0881093887702598	0.0380582183450398	63.2272098581606
a515	loss_cnaOV83	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	4.28563420739282	3.40710201812736	0.878532189265465	0.516947432031367	0.890233125896622	1.03358327844247	1.69946136653245	0.986856323034068	0.0345325109087197	NA	NA	0.639934883382475	0.0134258288553408	63.2272098581606
a516	loss_cnaOV33_(ZFHX3)	290	KIN001-260	IKK	4	27	2.99573227355399	NA	4.00584849545919	4.97534241019445	-0.969493914735263	0.693931481095136	0.860938133908741	1.14706769810931	1.3971032315831	1.12609010630493	0.0345622324953308	NA	NA	0.641285838066444	0.0584809443967176	63.2272098581606
a517	gain_cnaOV19	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.75652456366531	4.40717268799629	1.34935187566902	0.253096618682433	0.972385543992061	1.43291379810358	5.33137061527515	1.38767167406598	0.0345686018789806	NA	NA	0.161230337284916	0.000119952019000808	63.2272098581606
a518	TP53_mut	1067	CCT007093	PPM1D	23	10	1.88706964903238	NA	4.63639339649362	4.15239758760167	0.483995808891957	0.745311029398215	0.420485927260204	0.725093137771964	0.649387691582599	1.15103925604733	0.0345690341524054	NA	NA	0.0627557987568275	0.0249661889754339	63.2272098581606
a519	gain_cnaOV48_(SOX17)	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	2.84306896356429	3.94120685527513	-1.09813789171084	0.707201271310855	0.815078142995943	1.35815236680282	1.55279400116936	1.347279277634	0.0345846431227281	NA	NA	0.918273608336537	0.099933041452783	63.2272098581606
a520	loss_cnaOV52, loss_cnaOV53	341	EX-527	SIRT1	8	23	2.99573227355399	NA	6.17199566478558	5.63464110118694	0.537354563598647	0.366233090000305	0.553855786809511	1.04367841692691	1.46724743959701	0.970206642949567	0.0347202253390424	NA	NA	0.0868189942626106	0.00599170564991485	63.3329027786629
a521	loss_cnaOV52, loss_cnaOV53	170	Shikonin	unknown	5	13	2.77258872223978	NA	0.556974007357011	-0.229840665693609	0.786814673050619	0.71731274697953	0.708391184715488	1.10720399461933	1.09689208279617	1.11070647126507	0.0347876529256644	NA	NA	0.529264938688044	0.0735581271023	63.3329027786629
a522	loss_cnaOV44	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	4.21914430139307	2.15638505052774	2.06275925086533	2.05029777776294	1.38942368683955	1.43124442091839	1.00607788450905	1.48461500289907	0.0348427014901388	NA	NA	0.210771427368331	0.219707642757775	63.3329027786629
a523	loss_cnaOV102	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	5.33882500702929	4.29932842438857	1.03949658264072	0.427665326813742	0.727196124123737	1.46283548132634	2.43063095712092	1.42945836502264	0.0350255237429011	NA	NA	0.0302715154493301	0.0280407119011474	63.4350359852026
a524	loss_cnaOV83	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	0.129853997545926	-0.895793565339489	1.02564756288541	1.21516519216968	0.781925932076479	1.20618581812127	0.844039616584242	1.31169401194012	0.0350326024662401	NA	NA	0.0300759499689437	0.13314179783385	63.4350359852026
a525	loss_cnaOV41	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	5.47392725704987	3.60040353073848	1.87352372631139	1.13326584445475	1.6357197298671	1.18880771035856	1.65320761715253	1.14538187202988	0.0351027440296996	NA	NA	0.119683280994818	0.0149669722071847	63.4409737622183
a526	loss_cnaOV54	1021	Axitinib	PDGFR, KIT, VEGFR	10	20	0.693147180559945	NA	3.15323508904449	2.21130179533732	0.941933293707175	0.812730549708532	0.996723232043906	1.0004472705503	1.15897365251617	0.945029937524004	0.0351896712059242	NA	NA	0.163396058741147	0.0112599811853697	63.477167823005
a527	loss_cnaOV58	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	5.05184502302125	3.90479574835626	1.14704927466499	1.07575554558298	1.03951694053331	1.09826289302478	1.06627316900641	1.10344452306522	0.0353386456168535	NA	NA	0.806567005261859	0.0742329883385128	63.5176403602615
a528	loss_cnaOV56	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	1.06932843291655	-1.27963338961543	2.34896182253198	1.70337318266698	1.87031687580373	1.26311793242167	1.37900599025176	1.25591649892084	0.0353459942020331	NA	NA	0.410995006213563	0.126205033005461	63.5176403602615
a529	loss_cnaOV41	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.56899534854411	3.71144413593665	0.857551212607458	0.944074212027823	0.790460834324234	1.05620593466967	0.908351485171364	1.08487501893826	0.0354386538509894	NA	NA	0.918331038080345	0.113081895025445	63.5637661586189
a530	loss_cnaOV102	1061	SB590885	BRAF	3	30	1.6094379124341	NA	5.33061251764471	3.78723255491736	1.54337996272735	0.465428482606463	1.24531966360109	1.2752402783959	3.31604106840262	1.23934440918114	0.0355916229560857	NA	NA	0.546333653328777	0.0052704979350071	63.7176865344217
a531	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	5.023884982051	3.25392166015375	1.76996332189725	0.554246845150011	1.6943489253854	1.11558886270176	3.19345673752675	1.0446274054765	0.0358033693783803	NA	NA	0.676856692147999	0.000352689213842161	63.976054741877
a532	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-0.275248034459221	-2.97129354026889	2.69604550580967	2.81993856593689	1.54188087768205	1.54801059706934	0.956065333612662	1.74854331799141	0.0359412361981641	NA	NA	0.284203110978528	0.235604968300282	64.0904893249847
a533	gain_cnaOV19	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	1.40620124210774	0.27257554565361	1.13362569645412	0.556077790295093	0.868975744820957	1.33195711243162	2.03860991436566	1.30455389947356	0.0360475385015639	NA	NA	0.902816987663066	0.0478469806586278	64.0904893249847
a534	SMARCA4_mut	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	3.81373159296659	4.58883308259964	-0.775101489633049	0.815355835989739	0.534023873448668	1.39102502947382	0.950629719467419	1.45143602780814	0.0360714836700282	NA	NA	0.58951456541787	0.238159274219259	64.0904893249847
a535	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.969997394156	0.632912706527111	1.33708468762888	0.369035284096813	1.00636774954314	1.36869942346781	3.62318928636134	1.32862434059109	0.0361565676018988	NA	NA	0.755775485985248	0.0032550362523065	64.0904893249847
a536	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	4.41749510625089	1.79615203445186	2.62134307179903	3.32373511852219	1.68736135189235	1.42290893853275	0.788673879934374	1.5535161267379	0.036253830738356	NA	NA	0.107431507716327	0.304182397638334	64.0904893249847
a537	loss_cnaOV102	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	1.65393641576974	0.143842840181025	1.51009357558871	0.697025523623539	1.0774927958794	1.42854238725804	2.16648246643592	1.40148832675605	0.0363851310341782	NA	NA	0.121339240616849	0.0421450707293241	64.0904893249847
a538	loss_cnaOV16, loss_cnaOV17	255	CP724714	ERBB2	6	26	2.32630161961136	NA	5.11312767516321	4.25397921544517	0.859148459718043	0.620856863893121	0.938551389311702	0.961573699661735	1.38381084221361	0.915398420909173	0.0363930707173163	NA	NA	0.771310305582251	0.0190675765675505	64.0904893249847
a539	loss_cnaOV40	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	2.4804008614122	1.30834425884069	1.1720566025715	1.66998701395301	0.693380009919533	1.22168110459826	0.70183575846925	1.69035245580201	0.0365342146889536	NA	NA	0.407514275247506	0.193776049515763	64.0904893249847
a540	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	3.00477348823962	2.15729549913556	0.847477989104056	0.60839752729937	0.88162102503688	0.997998385132099	1.39296751067669	0.961272434568588	0.0365832174128462	NA	NA	0.566998654934461	0.0313002540815168	64.0904893249847
a541	loss_cnaOV83	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	5.25646041529525	4.22625201391607	1.03020840137917	0.566929963863619	0.957800920897629	1.12544410198148	1.81717049202748	1.07559763088731	0.0366619659378704	NA	NA	0.481495330170695	0.00948587944909944	64.0904893249847
a542	loss_cnaOV102	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	3.56603595827017	1.73384217813406	1.83219378013611	0.492780688351271	1.31741542240164	1.43101848659462	3.71807139250161	1.39074869549958	0.0367333886383164	NA	NA	0.0242150620319294	0.00310262388360592	64.0904893249847
a543	PIK3R1_mut	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	2.73245774297481	0.479222574632304	2.25323516834251	2.99118765345044	1.6568171571972	1.18246814099906	0.753291143651026	1.35997817173396	0.0367430646926405	NA	NA	0.38085879029272	0.169384425219907	64.0904893249847
a544	loss_cnaOV58	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	5	26	2.30258509299405	NA	2.70827385986257	1.15916941073598	1.54910444912658	2.38746228340444	1.10643749924786	1.14153367565348	0.648849810065947	1.40008310472091	0.0367455210877343	NA	NA	0.44416194920002	0.22284519374621	64.0904893249847
a545	PIK3CA_mut	228	KIN001-102	AKT1	6	26	2.32630161961136	NA	1.62469969190513	3.05751265806606	-1.43281296616093	0.995473269058524	1.11503443691656	1.30729477534019	1.43932841864857	1.28499436315449	0.0368450610601125	NA	NA	0.0741563810308758	0.0141752716452096	64.1461883170244
a546	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	344	THZ-2-49	CDK9	7	25	2.99573227355399	NA	4.16642339790235	2.14506239002566	2.02136100787669	2.15128223739034	2.19919852796341	0.923122705750266	0.939607538585332	0.919135304145819	0.0369499815050371	NA	NA	0.352946372158437	0.0541409329143776	64.1822651840785
a547	PIK3CA_mut	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	3.05368082049128	3.85722771138894	-0.803546890897659	0.942122854726602	1.01974581796007	0.799787003880693	0.852910941355778	0.787987434461954	0.0371032632919841	NA	NA	0.818967675698799	0.0778225184199179	64.1822651840785
a548	gain_cnaOV94	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	6.28735148080854	4.79632768553888	1.49102379526966	0.150706024068478	1.12210476977441	1.41289003904696	9.89359121167022	1.32877413538615	0.0371099304421909	NA	NA	0.774230584706761	9.58392371365932e-05	64.1822651840785
a549	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1262	UNC1215	LMBL3	8	25	0	NA	3.09332756217641	2.68027995009572	0.413047612080691	0.488343222897697	0.456873839347805	0.889869773941826	0.845814158390032	0.904073677473684	0.0371363578825131	NA	NA	0.0880079017337725	0.0576577475117024	64.1822651840785
a550	TP53_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	23	10	-1.38629436111989	0.693147180559945	-1.95716397248538	-3.08276301925721	1.12559904677183	1.5129181446255	1.60038804854169	0.731466610159709	0.743992033389526	0.703328825654194	0.0372641653147241	NA	NA	0.10113416399221	0.0769887014162709	64.2583477764593
a551	loss_cnaOV85	1072	BMS-708163	g-secretase	7	26	1.6094379124341	NA	4.42164223102042	3.68515065122323	0.736491579797192	0.890447928451115	0.795145530286937	0.904267652250735	0.827102356314399	0.926234949131163	0.0375401665735164	NA	NA	0.918466250784984	0.0792463733750697	64.2583477764593
a552	gain_cnaOV26	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	3.69520734202128	2.05388786997409	1.6413194720472	1.67472115274225	0.964879026852851	1.52958974236427	0.980055377792083	1.70106244033586	0.0376715445499168	NA	NA	0.329558548674891	0.227105396457783	64.2583477764593
a553	gain_cnaOV19	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	1.64605450158833	0.144631031599165	1.50142346998917	1.61943354238688	1.00801101101446	1.41888286801618	0.927128795773997	1.48949114006021	0.0376741628858028	NA	NA	0.121698661030253	0.246834187999914	64.2583477764593
a554	loss_cnaOV16, loss_cnaOV17	1019	Bosutinib	SRC, ABL, TEC	6	25	0.693147180559945	NA	3.07815954626334	1.39837614103504	1.6797834052283	1.26379047476846	1.49677945322591	1.15111584136183	1.32916289429706	1.12226514174013	0.0376945499872432	NA	NA	0.0291511694520942	0.0207807115893364	64.2583477764593
a555	BRCA1_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.76009185554472	1.20886690949146	1.55122494605326	1.11122289309432	1.40576670450507	1.12552874545225	1.39596201238593	1.10347253287621	0.0377904878756317	NA	NA	0.44455291106699	0.0584774492789647	64.2583477764593
a556	loss_cnaOV81_(RB1)	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-2.36984822545852	-4.24083629051584	1.87098806505733	1.76759043933689	1.3986481466978	1.31098893307453	1.0584963707765	1.3377117536492	0.0379031549659855	NA	NA	0.854091210177719	0.202391187605249	64.2583477764593
a557	gain_cnaOV48_(SOX17)	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	-0.401244482448724	0.878213590313806	-1.27945807276253	1.38701265552864	0.94854089302488	1.30043322294547	0.922455947076332	1.34886970311039	0.0379733540291009	NA	NA	0.75612080256225	0.247991506414033	64.2583477764593
a558	SMAD4_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	5.4164706542981	4.37761948480987	1.03885116948823	1.08872522396796	0.826282674648865	1.21195989963314	0.9541904115182	1.25725880665439	0.0380120522875018	NA	NA	0.498487122959339	0.150376797842493	64.2583477764593
a559	KRAS_mut	281	CH5424802	ALK	7	25	1.63315443905142	NA	3.43712513964523	4.0649401998731	-0.627815060227872	1.10809969196726	0.528832904668002	0.916436917193373	0.566569113572522	1.18717094697807	0.0380186324914578	NA	NA	0.952627486052989	0.190768545678165	64.2583477764593
a560	loss_cnaOV87, loss_cnaOV88	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.7865446747305	2.04818890258129	0.738355772149211	0.355223387806732	0.528777619005051	1.42173647919004	2.07856745218288	1.39634459858286	0.0381184335763101	NA	NA	0.0307573105241221	0.0478059143237343	64.2583477764593
a561	loss_cnaOV40	1129	PF-4708671	RPS6KB1 (p70S6KA)	8	24	2.30258509299405	NA	4.88642071335538	3.96723450580191	0.919186207553471	1.12663028648205	0.806656343268117	1.03088551598923	0.815872090944465	1.13950161704481	0.0382465361016804	NA	NA	0.0351059754797878	0.0601436151385066	64.2583477764593
a562	SMAD4_mut	1030	KU-55933	ATM	4	29	2.30258509299405	NA	5.10422118109769	4.01951523630767	1.08470594479002	0.782803029796548	0.989969258925164	1.1161215737716	1.38566906808209	1.09569659361717	0.0383348543016526	NA	NA	0.501950284918642	0.059983397041497	64.2583477764593
a563	loss_cnaOV85	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	1.72411960955015	0.629889902020229	1.09422970752992	1.75189722219149	0.966293137583613	0.938016070845568	0.624596976163433	1.13239933615408	0.0384545375062674	NA	NA	0.834009440766802	0.15636147872318	64.2583477764593
a564	loss_cnaOV55	341	EX-527	SIRT1	7	24	2.99573227355399	NA	6.19777446793781	5.64951205708415	0.548262410853665	0.387657950330865	0.546558773584253	1.05903525258756	1.41429425189326	1.003117024832	0.0384827395061005	NA	NA	0.0877749823821914	0.0101486217830994	64.2583477764593
a565	loss_cnaOV39	1066	AZD6482	PI3Kbeta	10	23	1.6094379124341	NA	3.18873143794474	2.02710591026157	1.16162552768317	1.22467027836427	1.1855071479452	0.970440018099873	0.94852104129995	0.979855355319101	0.0384846920511608	NA	NA	0.0886120539495564	0.0218596501676723	64.2583477764593
a566	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.61316650151562	4.33140056646766	1.28176593504796	0.9880337336861	0.908743920630446	1.40199565476727	1.29728964846779	1.410480891205	0.0385453632156833	NA	NA	0.0218164026350294	0.144079342430226	64.2583477764593
a567	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-2.65710023635131	-5.02853400280345	2.37143376645214	2.98302684452429	1.67509049667664	1.2634947932667	0.794975670703464	1.41570486559206	0.0385697459907275	NA	NA	0.290605898551391	0.300417526279106	64.2583477764593
a568	gain_cnaOV96	164	JQ12	HDAC	4	15	1.63315443905142	NA	3.68743791397616	1.28894776239598	2.39849015158018	1.26774842538674	2.11493283035916	1.20418947725739	1.89192911113141	1.13407391343623	0.0386169165519914	NA	NA	0.618438373732601	0.0205507701379782	64.2583477764593
a569	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	235	QL-XII-47	BTK, BMX	7	25	2.32630161961136	NA	2.59585278685671	1.27673095094213	1.31912183591458	1.12061785703797	1.6216383407453	0.859599815775489	1.17713797583174	0.813450078707634	0.0386274742962995	NA	NA	0.0607485257471755	0.0269449859187851	64.2583477764593
a570	NF1_mut	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	2.88991247038926	0.382754295640369	2.50715817474889	1.65489631787824	2.21621043590376	1.15716797493496	1.51499411030374	1.1312816392034	0.0386276007826251	NA	NA	0.941996150870705	0.0454448751199549	64.2583477764593
a571	loss_cnaOV59	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	3.06295888560171	1.19174304931998	1.87121583628173	2.18129167180881	1.61789654837637	1.11055501948095	0.857847604914771	1.15657322970345	0.0387645541248445	NA	NA	0.588957164974956	0.184270650501473	64.2583477764593
a572	loss_cnaOV43_(NF1)	1018	ABT-888	PARP1, PARP2	5	26	1.6094379124341	NA	5.02312006798103	4.16044347341654	0.862676594564494	0.515902832536186	0.768169639297151	1.16812295019306	1.6721687499244	1.1230287561922	0.0388226133610785	NA	NA	0.193688104469697	0.0142036640606354	64.2583477764593
a573	PIK3CA_mut	346	THZ-2-102-1	CDK7	6	26	0.916290731874155	2.99573227355399	-1.99051088473371	-0.844550680449825	-1.14596020428389	1.04806624180237	2.06742540568738	0.592170405790992	1.09340436565648	0.554293374325094	0.0388816226327087	NA	NA	0.412310604406729	0.0702554852950935	64.2583477764593
a574	ARID1A_mut	1028	VX-702	p38	9	22	0.693147180559945	NA	2.82250024361782	3.53334289445946	-0.710842650841641	0.897334602881469	0.862041717150405	0.815260962587304	0.792171224155431	0.82460353913199	0.0389757613284381	NA	NA	0.488070170215063	0.0618413576572054	64.2583477764593
a575	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1036	PLX4720	BRAF	8	25	2.30258509299405	NA	5.14082333529171	4.04135211243389	1.09947122285782	1.16336528643711	1.24606989180192	0.895421150229671	0.94507824470595	0.882351166729414	0.039092989180843	NA	NA	0.339805118016796	0.0402705588184648	64.2583477764593
a576	PTEN_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	2.61128609839623	0.83792516030619	1.77336093809004	0.689097589680054	1.5083129451725	1.20801888798344	2.57345398481717	1.17572480151805	0.0393422411969261	NA	NA	0.776670693670433	0.0185652701758149	64.2583477764593
a577	loss_cnaOV34	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.13237942862399	2.99920953249377	-0.866830103869783	0.289749085782225	0.788715380401441	1.16849045289513	2.99165777013457	1.09904044654053	0.0393949105012093	NA	NA	0.0129716347530147	0.000417846631366804	64.2583477764593
a578	loss_cnaOV44	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.36207357284254	0.565134042947918	0.796939529894623	0.740169160310207	0.560501096292413	1.38783892975561	1.07669918260391	1.42183402524312	0.0394056621578543	NA	NA	0.00978998676398333	0.197775988254468	64.2583477764593
a579	loss_cnaOV56	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	3.41771740489763	1.50421763058688	1.91349977431075	0.0929113303306536	1.42929851147573	1.38554792981179	20.5949023386165	1.3387684650529	0.0394437556762926	NA	NA	0.294111707394148	7.92731572600515e-08	64.2583477764593
a580	loss_cnaOV54	1218	JQ1	BRD2, BRD3, BRD4	9	22	0	NA	2.75097812342106	2.10703396854242	0.643944154878639	0.324406057415498	0.986418557724193	0.75181099180357	1.98499423842101	0.65281025973833	0.0394672787082011	NA	NA	0.567901899354133	0.0109426688212112	64.2583477764593
a581	gain_cnaOV49	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	1.9222539815657	3.14156633639144	-1.21931235482574	0.986647782886508	1.15418664992408	1.06637252662297	1.23581320099717	1.05642562657084	0.0394750707483163	NA	NA	0.0686858737020435	0.152410763816092	64.2583477764593
a582	loss_cnaOV44	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.6107749710762	-4.34613465558565	1.73535968450945	3.1250317635955	0.981794883435305	1.39355320494584	0.555309454683057	1.76753791834544	0.0395230952014435	NA	NA	0.187905501337806	0.437834430405382	64.2583477764593
a583	loss_cnaOV16, loss_cnaOV17	151	QS11	ARFGAP	3	16	2.32630161961136	NA	5.37976718743254	3.46434428048721	1.91542290694533	1.16828016997152	1.29512936875906	1.49542159432446	1.63952359731658	1.47894330338644	0.0395288867983549	NA	NA	0.0389848462101717	0.0830268549741563	64.2583477764593
a584	loss_cnaOV58	306	TG101348	JAK2	5	27	2.32630161961136	NA	4.02759840449002	2.60118088005007	1.42641752443994	1.05729789976153	1.3366714480169	1.09481255820374	1.34911601050344	1.06714146288992	0.0395759612378654	NA	NA	0.603563328226261	0.0346328371861966	64.2583477764593
a585	KRAS_mut	1007	Docetaxel	Microtubules	7	24	-4.38202663467388	NA	-5.69366262238517	-4.34375775804543	-1.34990486433975	0.715908026642956	1.42351002855656	1.03134280827437	1.88558420090599	0.94829318884992	0.0397570315861267	NA	NA	0.110272144390747	0.00274699928405904	64.2583477764593
a586	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.62811890702852	2.85342457409026	0.774694332938253	0.412478592992356	0.546098913528565	1.45585508420379	1.87814433548703	1.4185970961426	0.0397758890151554	NA	NA	0.829878890505927	0.0560578924314968	64.2583477764593
a587	SMAD4_mut	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	4.12483440202536	2.44349807957836	1.68133632244701	1.53684932059929	1.12937377441025	1.41931710693222	1.09401507350856	1.48873327904659	0.0398078726275577	NA	NA	0.933335662494349	0.190205609474093	64.2583477764593
a588	loss_cnaOV85	1053	MK-2206	AKT1, AKT2	7	25	1.38629436111989	0.693147180559945	2.23830271784348	1.04993646056926	1.18836625727423	1.134636295999	1.11403027761004	1.06276653165067	1.04735434734874	1.06672707300529	0.0398216090328237	NA	NA	0.0771798171195369	0.0348991216904215	64.2583477764593
a589	loss_cnaOV41	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	3.22820938304332	2.62118891887039	0.60702046417293	0.648143140488378	0.505886648249538	1.15167273143059	0.936553094915945	1.19991398522443	0.0399340773580911	NA	NA	0.11127274992552	0.104534244246161	64.2741195333699
a590	BRCA1_mut	1028	VX-702	p38	4	27	0.693147180559945	NA	4.17459561269023	3.20139494147806	0.97320067121217	0.245871803629348	0.915538743216335	1.11799134457073	3.95816298106013	1.06298141768776	0.0399668638595095	NA	NA	0.48840417963542	0.00023417171247364	64.2741195333699
a591	KRAS_mut	1028	VX-702	p38	7	24	0.693147180559945	NA	2.67522995942285	3.51705983977952	-0.841829880356675	0.925543231111537	0.841689174763833	0.979202612852546	0.909552198167636	1.00016717049127	0.0402196644572048	NA	NA	0.488487964846651	0.0587239921360252	64.3838866311208
a592	BRCA1_mut	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.61343318162482	5.85533130234995	0.758101879274866	0.276496289030447	0.689254369446029	1.14746058399457	2.74181574708724	1.09988693997569	0.0402351894173227	NA	NA	0.902581237089859	0.00263602118267016	64.3838866311208
a593	gain_cnaOV48_(SOX17)	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	-0.642805441778727	1.75593449970889	-2.39873994148762	0.785924027544828	1.84593388231654	1.33645725609266	3.05212699627102	1.29947229663358	0.0403436386169943	NA	NA	0.767890635310954	0.00903139352628941	64.3838866311208
a594	gain_cnaOV95_(MECOM)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	8	25	0.693147180559945	NA	2.75468991171177	1.41237998868792	1.34230992302385	1.11748915084892	1.72591035962101	0.834372891908911	1.20118385221382	0.777740231722469	0.0404179566606102	NA	NA	0.20022801637278	0.0194133390588701	64.3838866311208
a595	loss_cnaOV56	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.79930439731012	3.74558331190055	1.05372108540957	0.944816141250521	0.803908563643369	1.29491759423042	1.11526575320242	1.3107474320637	0.0404335717336623	NA	NA	0.918639647786698	0.186343689963376	64.3838866311208
a596	gain_cnaOV94	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-1.49895623304564	-2.48129910975895	0.982342876713317	0.457031876259993	0.688974182799506	1.47522549778439	2.14939685334878	1.42580506097016	0.0404907718129444	NA	NA	0.63462902781035	0.035962749385718	64.3838866311208
a597	PIK3CA_mut	1072	BMS-708163	g-secretase	7	26	1.6094379124341	NA	3.38796963987627	3.96344711806973	-0.575477478193454	0.823040282095108	0.840582527719458	0.687370426277966	0.699209371294119	0.68461746374238	0.0405101120568308	NA	NA	0.918644051397185	0.134252788086002	64.3838866311208
a598	loss_cnaOV54	206	Ruxolitinib	JAK1, JAK2, TYK2	10	22	1.65632149833295	0.0237165266173161	4.77009985523536	4.30731328534892	0.462786569886443	0.324667957006169	0.578259439267375	0.897825341918582	1.4254149813671	0.800309581582914	0.0408130578755113	NA	NA	0.333050356035543	0.00740507326285352	64.7568966233671
a599	loss_cnaOV83	1025	SB 216763	GSK3A, GSK3B	4	19	2.30258509299405	NA	5.75185278153131	4.79324098116633	0.958611800364981	0.54758882210738	0.771163915088227	1.28957809468199	1.7506051286361	1.24307139067225	0.0410511687041153	NA	NA	0.409825194983624	0.0266659038440737	64.9989096689977
a600	gain_cnaOV18_(CCNE1)	326	GSK690693	AKT	4	28	2.32630161961136	NA	5.62505420252054	3.94148499817526	1.68356920434528	0.311082805924417	1.42223653181032	1.2444763331863	5.41196482827899	1.18374768661182	0.0411866285688721	NA	NA	0.0739979650772681	1.44641513139012e-05	64.9989096689977
a601	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	205	BMS-708163	g-secretase	7	25	2.32630161961136	0.940007258491471	5.45441132660362	4.95213069631289	0.502280630290724	0.366547689484718	0.627343425211142	0.859234490660637	1.37030090408377	0.800646998287539	0.0412063125758474	NA	NA	0.0890339776169939	0.015574763412802	64.9989096689977
a602	loss_cnaOV87, loss_cnaOV88	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	2.26878857023077	0.724473072643603	1.54431549758717	2.28606904303325	1.04259204658051	1.32281103231495	0.675533183170229	1.48122700787159	0.0412396039886369	NA	NA	0.834349168435179	0.362309132484983	64.9989096689977
a603	NF1_mut	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	4.15225706629633	2.72718948311952	1.42506758317681	0.996930478100268	1.17674861423413	1.22848343544594	1.42945532760959	1.21102125461545	0.0415437346958493	NA	NA	0.201857716100939	0.0552955086779194	65.0856756518783
a604	loss_cnaOV102	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	5.13357037489534	3.55109800043346	1.58247237446187	0.305517608033671	1.1774555734041	1.38633291768495	5.17964376798692	1.34397629108574	0.0415537473079522	NA	NA	0.170812769592862	0.000154361713064601	65.0856756518783
a605	PIK3CA_mut	224	AS605240	PI3Kgamma	6	26	2.99573227355399	2.32630161961136	2.49788916752673	3.57753458784444	-1.07964542031772	1.35854641732858	1.67356866242394	0.664270184214038	0.794706317389366	0.645115700693148	0.0416222620378806	NA	NA	0.60653386500827	0.128593802687396	65.0856756518783
a606	RB1_mut	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	-0.612547168597547	0.488870018229176	-1.10141718682672	0.213540737436556	0.884234701013135	1.28814673426333	5.15787853900224	1.24561633417547	0.0416541039326241	NA	NA	0.903247553051324	0.000147489855861709	65.0856756518783
a607	loss_cnaOV102	309	Y-39983	ROCK	3	29	2.99573227355399	NA	6.39233171455128	4.81656110120412	1.57577061334716	0.19099559324392	1.19319436983218	1.3657347371097	8.25029827434158	1.32063195501735	0.0416997965904636	NA	NA	0.341145295564505	1.55072405721861e-06	65.0856756518783
a608	KRAS_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	-1.38629436111989	0.693147180559945	-2.94018506666009	-1.90371952188087	-1.03646554477923	1.22428578165143	1.22928523267673	0.843807991746836	0.846587912979882	0.843144875760327	0.0417720508264479	NA	NA	0.584098001986952	0.0764732764170189	65.0856756518783
a609	SMARCA4_mut	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	3.36763901749497	4.64434009232973	-1.27670107483476	1.66067799252743	0.846994572143313	1.38555789386271	0.768783039565495	1.50733088124058	0.0418047052493058	NA	NA	0.295053560918161	0.313571895582569	65.0856756518783
a610	loss_cnaOV42	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	5.44457644266453	4.3097075057661	1.13486893689843	0.864104681062079	0.918819252625447	1.24233694624088	1.31334659072041	1.23513839490807	0.0420082049722373	NA	NA	0.022126200135704	0.070860899834735	65.0856756518783
a611	loss_cnaOV59	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.70270402305223	4.83214015606144	0.870563866990793	0.614905822508767	0.786675833940671	1.12807426356425	1.41576780561121	1.1066360874846	0.0420230091202625	NA	NA	0.942417790025398	0.0562892631806415	65.0856756518783
a612	loss_cnaOV43_(NF1)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	0.871201023943846	-0.839487044064907	1.71068806800875	1.88921025518219	1.75428635283833	0.966111931831435	0.905504330879138	0.975147566553749	0.0420418570292202	NA	NA	0.024289999805323	0.251541701659136	65.0856756518783
a613	loss_cnaOV16, loss_cnaOV17	304	SB52334	ALK5	6	26	2.99573227355399	NA	5.06753220377189	4.20489623158269	0.862635972189202	0.801640334863651	1.05039407199337	0.851409943463829	1.07608853331454	0.82124984821377	0.0420568050630807	NA	NA	0.320380793805753	0.0512707891698306	65.0856756518783
a614	loss_cnaOV85	1268	XAV 939	TNKS1 (tankyrase-1)	7	25	1.6094379124341	NA	3.46576174284996	2.68509092391945	0.780670818930514	1.24656914760764	0.966466564613221	0.75895903293936	0.626255527363841	0.807757709903744	0.0421178033128428	NA	NA	0.27554938641758	0.163225004636498	65.0856756518783
a615	loss_cnaOV43_(NF1)	1262	UNC1215	LMBL3	5	28	0	NA	3.22805814084574	2.70047601948485	0.527582121360893	0.540008305896473	0.44578968621088	1.1493290275368	0.976988901096713	1.18347763010228	0.0424927210728447	NA	NA	0.089184102059532	0.0938649575663377	65.3592037170359
a616	loss_cnaOV38	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	7	16	2.30258509299405	NA	2.28123313514317	1.24897306376196	1.03226007138122	1.47659914134793	0.654886281640137	1.07080934606563	0.699079420050934	1.57624323538426	0.0424994210401944	NA	NA	0.410542137206666	0.118857559418638	65.3592037170359
a617	loss_cnaOV102	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	5.34510220885484	3.82226527823501	1.52283693061983	0.438160708256815	1.11431705066713	1.40827966740585	3.47552142837796	1.36661009513237	0.0425115961619503	NA	NA	0.0643561423668397	0.00441220162657458	65.3592037170359
a618	loss_cnaOV43_(NF1)	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.93630041318867	4.36223662089209	0.574063792296573	0.506345255537586	0.519887103985589	1.10801313258392	1.13373984651459	1.10420856354322	0.0426012339477431	NA	NA	0.333655796968931	0.0619465322186292	65.3592037170359
a619	TP53_mut	1175	AG-014699	PARP1, PARP2	23	10	1.6094379124341	NA	4.13360991823358	3.36651836515391	0.767091553079674	1.12373472786649	0.707596934992372	0.751642872580584	0.682626899442779	1.08407981316078	0.0426479122845079	NA	NA	0.286278058000466	0.0254681696826095	65.3592037170359
a620	gain_cnaOV72_(ASXL1)	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	1.315190800734	3.01454246078367	-1.69935166004967	1.16396769647052	1.62277919351675	1.08282162934877	1.45996462376282	1.04718600462641	0.0427106657385953	NA	NA	0.290129365625614	0.02560324498641	65.3592037170359
a621	KRAS_mut	253	XMD14-99	EPHB3, CAMK1	7	25	2.32630161961136	NA	4.37724796945869	4.99525233991687	-0.618004370458184	0.338595005065485	0.611054439898078	1.08970003886457	1.82520226587117	1.01137366837767	0.0428288127865982	NA	NA	0.0369219627198782	0.00257284638429605	65.3592037170359
a622	TP53_mut	1069	EHT 1864	Rac GTPases	23	10	2.30258509299405	NA	4.43594992001593	3.7540859126775	0.681864007338425	0.951772068073553	0.88110436976606	0.731764558025153	0.716415232397564	0.773874277254424	0.0428458793521932	NA	NA	0.182060511662407	0.0611898521563677	65.3592037170359
a623	loss_cnaOV40	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.6094379124341	NA	2.04131327164364	0.888373277659473	1.15293999398417	1.6930137051982	1.32423732302085	0.814263512074064	0.680998618288914	0.870644539268901	0.0430801239750664	NA	NA	0.80114073930481	0.108961294413403	65.4240013532076
a624	loss_cnaOV56	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.63450450344121	-4.34367987637547	1.70917537293426	3.13222610534672	0.984613254808121	1.36892329362712	0.545674327283298	1.73588499300402	0.0431035567748998	NA	NA	0.189010014436988	0.44458744441992	65.4240013532076
a625	SMAD4_mut	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.9186850365895	3.82903682484395	1.08964821174555	0.634518648464477	1.1577399872952	0.977212481523422	1.71728319472166	0.941185606183706	0.0432132819890753	NA	NA	0.064482394531297	0.0281904348792046	65.4240013532076
a626	loss_cnaOV20	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	3.51377557399076	2.83226984070445	0.681505733286312	0.390611610132368	0.560955342939405	1.27419608115687	1.74471448264266	1.21490193803169	0.0432641137942839	NA	NA	0.830643917030635	0.0273497217397825	65.4240013532076
a627	loss_cnaOV44	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.60215993965787	1.31680014990511	2.28535978975277	1.63392876787909	1.8200177031622	1.26388125167577	1.39868997638083	1.25567997815739	0.0434689443992128	NA	NA	0.768388641707541	0.122631650087205	65.4240013532076
a628	gain_cnaOV48_(SOX17)	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	1.6395953082242	2.90774970125779	-1.26815439303358	1.46113698616179	1.15578277802559	1.07598046290325	0.867922997668308	1.09722554890458	0.0435699310792081	NA	NA	0.0755289193259126	0.268400883864459	65.4240013532076
a629	loss_cnaOV44	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-2.98640446551296	-4.82666468404456	1.8402602185316	1.79016618511884	1.2761547805718	1.39619370149208	1.02798289557092	1.44203528172895	0.0435740197479286	NA	NA	0.11123338455779	0.212330498048033	65.4240013532076
a630	loss_cnaOV84	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	1.38629436111989	NA	0.22873646563063	1.43546446291649	-1.20672799728586	1.57787996732303	1.05147923593277	1.04681855780614	0.76477807075094	1.14764795732306	0.0436940685151357	NA	NA	0.237820496840292	0.123933353155673	65.4240013532076
a631	gain_cnaOV48_(SOX17)	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	-0.457434428481467	1.07907716446506	-1.53651159294653	1.65213951584142	1.14519024343872	1.29271441170794	0.930013221167945	1.34170859536208	0.0437211850429376	NA	NA	0.954397988314433	0.244969686284419	65.4240013532076
a632	loss_cnaOV38	170	Shikonin	unknown	3	15	2.77258872223978	NA	-0.866269471946063	0.159716653240422	-1.02598612518649	0.938871348014863	0.650326650889002	1.48050703548296	1.09278670326431	1.57764736195872	0.0439236736097562	NA	NA	0.53478005892702	0.190867922283841	65.4240013532076
a633	loss_cnaOV43_(NF1)	1004	Vinblastine	Microtubules	5	26	-2.30258509299405	NA	-1.68446516290095	-3.62878859810328	1.94432343520234	1.8095102365667	1.66189367815612	1.15525556325367	1.07450258965731	1.1699445402305	0.0439915458159581	NA	NA	0.114998580865977	0.0725050102611426	65.4240013532076
a634	loss_cnaOV36	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.980236078952085	-1.27041693920531	2.25065301815739	1.73602478923542	1.87988557637439	1.20314657807028	1.29644059930079	1.19722872840914	0.0440164940530174	NA	NA	0.414011525133453	0.141510489506119	65.4240013532076
a635	NF1_mut	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	4.59386832524875	2.30057322267725	2.2932951025715	2.32529229241364	2.20739563089633	1.03326382707791	0.986239497741195	1.0389143977966	0.0440440591702302	NA	NA	0.355422320090212	0.140397744257427	65.4240013532076
a636	loss_cnaOV102	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.77639047688137	4.98810259528978	0.788287881591595	0.218203388210815	0.593013348617705	1.36934246694158	3.6126289699498	1.32929196860251	0.0440584568472675	NA	NA	0.0896383537060795	0.00332485359766592	65.4240013532076
a637	gain_cnaOV94	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.45275085480769	4.58864796485935	0.864102889948348	0.366917323249439	0.641480307365523	1.40374843764927	2.35503432297992	1.347045076874	0.0441708116943792	NA	NA	0.951476763906689	0.0244507260025527	65.4240013532076
a638	PTEN_mut	305	TPCA-1	IKK	3	29	2.99573227355399	NA	4.48307549237143	3.20541427202646	1.27766122034497	0.619452402881876	1.20968600421103	1.08316614492666	2.06256560536517	1.05619244655002	0.0442377965152195	NA	NA	0.993184988065044	0.0409871745584444	65.4240013532076
a639	TP53_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	23	10	1.38629436111989	0.693147180559945	3.17855807341666	1.99445406942894	1.18410400398772	1.45618971355908	1.50084884034706	0.805899370053489	0.813152292563342	0.788956204086417	0.0443068035039797	NA	NA	0.966804443193653	0.0510553401182391	65.4240013532076
a640	loss_cnaOV85	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.99268179393623	4.34272494363516	0.649956850301073	0.628540030123223	0.619929832890112	1.04541556792029	1.03407391598217	1.04843615489672	0.0443357179593815	NA	NA	0.0398059700835369	0.0371357520057699	65.4240013532076
a641	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	255	CP724714	ERBB2	5	27	2.32630161961136	NA	5.16986592689413	4.27529244511418	0.89457348177995	0.597645807822672	0.935267777425215	0.996607173052032	1.49682884087991	0.956489150350827	0.0443793353247371	NA	NA	0.772616642693302	0.0235255911987873	65.4240013532076
a642	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	255	CP724714	ERBB2	7	25	2.32630161961136	NA	5.05362914268631	4.23627286614998	0.817356276536327	0.584741247861286	0.95399704242446	0.915853355304897	1.39780848285603	0.856770241613246	0.0445204477631876	NA	NA	0.772637383231041	0.0128302523820725	65.4240013532076
a643	loss_cnaOV56	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	4.13077662074904	2.96156455963171	1.16921206111733	0.660198917447807	0.870818856925602	1.36146338523867	1.77099966421827	1.34265817950383	0.0446810431479683	NA	NA	0.210774009188946	0.073163791685321	65.4240013532076
a644	loss_cnaOV85	1038	NU-7441	PRKDC (DNAPK)	7	26	0.693147180559945	NA	3.27457608995865	2.33847842579644	0.936097664162205	0.850174694279952	0.991929411648971	0.968927223217931	1.10106507575484	0.943713991307151	0.0446937123653441	NA	NA	0.365913626185489	0.0301865693577762	65.4240013532076
a645	loss_cnaOV57_(ZNRF3)	306	TG101348	JAK2	4	28	2.32630161961136	NA	4.16150790664586	2.63299443418638	1.52851347245947	1.17088005363603	1.3224430792481	1.16851925363675	1.3054398422049	1.1558255296164	0.0447406479884109	NA	NA	0.60487323843861	0.0715323751163379	65.4240013532076
a646	loss_cnaOV33_(ZFHX3)	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.98176889385901	2.94179969226767	1.03996920159134	0.611868990841053	0.879662828037895	1.21291859870921	1.69965992256256	1.1822361573593	0.0447489146537652	NA	NA	0.210793289615801	0.0308291139155433	65.4240013532076
a647	gain_cnaOV19	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.85298817455319	2.69235404003009	1.16063413452311	0.273802204477094	0.934857351480099	1.2798262679961	4.23895102210619	1.24150934116905	0.0448308838223072	NA	NA	0.96403047375531	0.000866722762258515	65.4240013532076
a648	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	283	GSK2126458	PI3K, MTOR	7	25	-2.05572501506252	0.0237165266173161	-1.55937613776161	-3.06056887792983	1.50119274016822	1.51811667245621	1.69867192777808	0.902089267318739	0.988852021326784	0.883744951346685	0.0449980129137464	NA	NA	0.677305776822462	0.0466109474630992	65.4240013532076
a649	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	163	JQ1	BRD4	3	16	0.940007258491471	NA	1.93507491398862	-0.257719606011334	2.19279451999995	1.88544292816358	1.66209974559083	1.29758205812714	1.16301293836337	1.31929177284151	0.0450306547516057	NA	NA	0.536152965504225	0.169670202439956	65.4240013532076
a650	loss_cnaOV16, loss_cnaOV17	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-1.51429996941355	-2.47842215918997	0.964122189776423	0.403819856928541	0.697686406493552	1.43933393729872	2.38750564944862	1.38188472758403	0.0450895567328363	NA	NA	0.636594014027185	0.0234911429911965	65.4240013532076
a651	loss_cnaOV87, loss_cnaOV88	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.4338911772559	4.30967421106158	1.12421696619432	0.659974367081689	0.911051891160861	1.25400144930597	1.70342519689884	1.23397687563311	0.04508989921706	NA	NA	0.772720365397478	0.0779823311708218	65.4240013532076
a652	gain_cnaOV50	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	4.39275828100731	2.51419883288571	1.8785594481216	1.64616345378834	1.55860670180189	1.19837998496457	1.14117431279285	1.20528125918477	0.0450899899886167	NA	NA	0.29088876485008	0.101511437014671	65.4240013532076
a653	loss_cnaOV38	273	CUDC-101	HDAC, EGFR	8	23	1.63315443905142	NA	-0.920268256014286	0.479236570170898	-1.39950482618518	1.04435977605438	1.62996519503741	0.927096325101203	1.34006006193818	0.85861025158458	0.0451740007468365	NA	NA	0.4320487884839	0.0115369845349193	65.4240013532076
a654	loss_cnaOV54	1019	Bosutinib	SRC, ABL, TEC	10	21	0.693147180559945	NA	2.71475907896125	1.25146523875445	1.4632938402068	1.34570085540282	1.49338806928635	1.00974915373408	1.08738419414082	0.979848353084859	0.0451909904017276	NA	NA	0.029986145331142	0.0130473018087537	65.4240013532076
a655	KRAS_mut	1032	Afatinib	ERBB2, EGFR	7	24	-0.693147180559945	NA	1.43046501140663	0.0440298184660392	1.38643519294059	0.782786487385603	1.72844161940087	0.877529005100214	1.77115371213303	0.802130183269466	0.0452464286807809	NA	NA	0.826234710676997	0.00621884064764563	65.4240013532076
a656	loss_cnaOV43_(NF1)	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	2.60191661103728	1.36302765936268	1.2388889516746	0.923974459645664	0.956557978142035	1.30110734599382	1.34082597061146	1.29515301736435	0.0452830539557739	NA	NA	0.245772560409967	0.066060877841135	65.4240013532076
a657	BRCA1_mut	1026	17-AAG	HSP90	4	29	0	NA	1.28327342666906	-0.781053618284409	2.06432704495347	2.40037147477171	2.18726040011752	0.934599353140846	0.860003156448857	0.943795738652131	0.0454043714210068	NA	NA	0.0473471108473211	0.183891582792731	65.4240013532076
a658	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.43243687191311	4.30982465644187	1.12261221547124	0.661621418820092	0.911158693419583	1.25195696911418	1.69675917909862	1.23207101416996	0.0454144296829654	NA	NA	0.772767152215243	0.0787214246138097	65.4240013532076
a659	loss_cnaOV43_(NF1)	1030	KU-55933	ATM	5	28	2.30258509299405	NA	5.02785801254061	3.99441201837893	1.03344599416168	0.959865913297314	0.966072510447478	1.07062460962317	1.07665662447748	1.06973957232568	0.0456612299382991	NA	NA	0.504075714640139	0.072236202782794	65.4240013532076
a660	ARID1A_mut	1059	AZD8055	MTORC1/2	9	24	0.693147180559945	NA	-0.497647424394701	0.573163386345511	-1.07081081074021	0.68168868364903	1.13514598433726	1.03232649333393	1.57082086944474	0.943324317325929	0.0457034784949125	NA	NA	0.123691291077133	0.00299431684756362	65.4240013532076
a661	KRAS_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	NA	0.509975008773651	1.40615900888898	-0.896184000115332	1.22814462645301	1.18090515092433	0.7529726569577	0.729705590703589	0.758895834617928	0.0457575245629253	NA	NA	0.238425133625629	0.117329818132787	65.4240013532076
a662	loss_cnaOV36	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	5.28505409040763	4.17375605690952	1.11129803349811	1.25274020011334	0.801305393959824	1.32456275777182	0.88709377522775	1.38685954428235	0.0459180850159037	NA	NA	0.494811214693858	0.261678934684337	65.4240013532076
a663	loss_cnaOV44	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	3.2253553088373	2.19419587472182	1.03115943411549	0.735027882908809	0.859848449285184	1.21052605793936	1.40288478585977	1.19923392892401	0.0459718147862335	NA	NA	0.56970336857912	0.120573261711649	65.4240013532076
a664	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	2.2395620066552	0.727496510254869	1.51206549640033	2.31989199573216	1.04184515322239	1.29096311750608	0.651782711946088	1.45133419464837	0.0460767784189406	NA	NA	0.834884209326935	0.376045500117223	65.4240013532076
a665	BRCA1_mut	1061	SB590885	BRAF	4	29	1.6094379124341	NA	5.14864996107411	3.75911083986754	1.38953912120658	0.144153597481898	1.26849206112545	1.15181995807783	9.63929548397892	1.09542595006368	0.0462793769398998	NA	NA	0.549333996713244	3.43658970851609e-06	65.4240013532076
a666	loss_cnaOV43_(NF1)	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.52033184553108	5.84488147382116	0.675450371709922	0.591995812100779	0.672590527719456	1.01917518381288	1.14097153713469	1.00425198374435	0.0462962506574066	NA	NA	0.902969794743848	0.0610383598432002	65.4240013532076
a667	PIK3R1_mut	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	4.7657776580348	3.11756837033118	1.64820928770361	0.598580918003261	1.66453601335137	1.05321094419059	2.75352794940689	0.990191425408162	0.0463269554490039	NA	NA	0.607668392938405	0.00094401864723028	65.4240013532076
a668	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	2.88177112586945	0.857540747177372	2.02423037869208	1.80591781157115	1.33563368906785	1.44671623115871	1.12088732151714	1.51555804204429	0.0463697490088431	NA	NA	0.486039347940965	0.18286406870675	65.4240013532076
a669	loss_cnaOV102	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	3.7210398249241	2.39241730823774	1.32862251668636	0.668100976373273	0.982080360057388	1.37959292333433	1.98865525372927	1.35286537713545	0.0465177541563797	NA	NA	0.16703435952435	0.0521452998901666	65.4240013532076
a670	loss_cnaOV44	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	5.35503073199032	4.11675383637235	1.23827689561797	1.00791550552818	0.908639202807203	1.35276239737404	1.22855228322843	1.36278171995261	0.0465631243436848	NA	NA	0.183070140675292	0.158627801513674	65.4240013532076
a671	loss_cnaOV83	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	2.21466242756099	1.50332826791914	0.711334159641846	0.714179183868239	0.622671259948795	1.11909407661245	0.996016371954468	1.14239118680432	0.0466572438086683	NA	NA	0.181712726498081	0.089410982061976	65.4240013532076
a672	loss_cnaOV44	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.955679131135306	-1.26787656529323	2.22355569642853	1.74731479857835	1.88226799655635	1.18679924934682	1.27255586585638	1.18131727283074	0.0466834780879141	NA	NA	0.414813711619948	0.146366169382571	65.4240013532076
a673	loss_cnaOV41	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	1.45175112588396	-0.396226060028609	1.84797718591257	1.67197201875369	1.46790695300223	1.23999227451093	1.10526800998146	1.25891983966219	0.0467669293056389	NA	NA	0.0806151901036485	0.109576535091227	65.4240013532076
a674	loss_cnaOV42	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	1.45175112588396	-0.396226060028609	1.84797718591257	1.67197201875369	1.46790695300223	1.23999227451093	1.10526800998146	1.25891983966219	0.0467669293056389	NA	NA	0.0806151901036485	0.109576535091227	65.4240013532076
a675	gain_cnaOV72_(ASXL1)	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.90279389011168	3.83139106876659	1.07140282134509	0.333996816024745	1.17440582805477	0.959024699655363	3.20782345801079	0.912293515368284	0.046779108340695	NA	NA	0.0650944757673837	0.00135002655201666	65.4240013532076
a676	loss_cnaOV57_(ZNRF3)	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.63038843533165	3.73254685543518	0.897841579896467	0.842169085965596	0.814904564542339	1.09816592935224	1.06610607639087	1.10177512676065	0.0468211040165156	NA	NA	0.918979216641261	0.118598967860533	65.4240013532076
a677	loss_cnaOV102	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.82033792580549	4.84939556135247	0.970942364453019	0.679539346772578	0.779739505111673	1.25498793647565	1.42882434853028	1.24521376445325	0.0470321768228089	NA	NA	0.942602530915545	0.11753544320179	65.4240013532076
a678	BRCA1_mut	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.54438060425357	2.05613029946951	0.488250304784061	0.145050123807792	0.565264478158915	0.90566183742281	3.36607988994927	0.863755504988228	0.0470652434621357	NA	NA	0.0317016961683409	0.00109086362917238	65.4240013532076
a679	loss_cnaOV102	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	4.43232173495603	2.47738873194413	1.9549330030119	1.55314661217173	1.62026002158768	1.20972511187747	1.25869186314508	1.20655510656634	0.0471078816122423	NA	NA	0.619352207594853	0.1500411795448	65.4240013532076
a680	ARID1A_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	8	24	1.65632149833295	0.0237165266173161	4.09682085578751	4.57030516598874	-0.473484310201227	0.396449047551161	0.551592487315224	0.911330616774973	1.19431314850145	0.858395139690582	0.0471175063261763	NA	NA	0.335073071795033	0.0175356636745971	65.4240013532076
a681	gain_cnaOV48_(SOX17)	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	2.27332322151247	3.89513824446914	-1.62181502295667	1.35156611364422	1.50735184747925	1.08280520307236	1.19995241563417	1.07593660078026	0.0471902055565651	NA	NA	0.141138017499763	0.161847476548783	65.4240013532076
a682	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	223	ZSTK474	PI3K	7	25	1.63315443905142	2.32630161961136	1.44841737127323	0.565021562913665	0.883395808359562	0.590764270530949	1.06318918942732	0.89506406787748	1.49534400170412	0.830892391631065	0.0472054589203194	NA	NA	0.757638172739351	0.0102543714697429	65.4240013532076
a683	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.88376366041051	2.82628603453792	1.0574776258726	0.45604087799249	0.987325457524879	1.12993296608402	2.31882201114877	1.0710527291817	0.047206627895902	NA	NA	0.0704933761609274	0.00233656152340497	65.4240013532076
a684	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1019	Bosutinib	SRC, ABL, TEC	8	23	0.693147180559945	NA	2.67524333612283	1.3924527875858	1.28279054853703	1.5555351418167	1.48786733304074	0.852647337899312	0.824661889051804	0.862167291431423	0.0472771242623058	NA	NA	0.0301952630289095	0.0653780429623885	65.4240013532076
a685	loss_cnaOV20	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.88503276641361	0.681145221677361	1.20388754473625	2.14354246167953	0.938054963899593	1.02658266244214	0.561634568131188	1.28338699870161	0.0473479472160321	NA	NA	0.835014761382695	0.280472336108985	65.4240013532076
a686	loss_cnaOV35	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	4.83379909698366	5.66929148428785	-0.835492387304189	1.85841632959263	0.694954760009356	0.891112925095333	0.449572237393831	1.20222557694682	0.0473510274373376	NA	NA	0.274578406426172	0.374521512177445	65.4240013532076
a687	loss_cnaOV39	266	Zibotentan, ZD4054	Endothelin A Receptor	9	23	2.99573227355399	NA	5.48699938611458	5.8043197759208	-0.317320389806221	0.579477525994162	0.406173821475436	0.691580363476771	0.547597405545314	0.781242839958388	0.0474851482137198	NA	NA	0.352183016327741	0.160063384710438	65.4240013532076
a688	loss_cnaOV43_(NF1)	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	4.38176229738783	3.12038747475518	1.26137482263266	0.787021528541554	0.873520217236843	1.46027341761844	1.60271959138162	1.44401331273441	0.0475055779853403	NA	NA	0.144111520956751	0.087291676563735	65.4240013532076
a689	SMAD4_mut	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.71886825628045	3.84575090363803	0.873117352642419	0.340514490205674	0.705343714934009	1.27077391947432	2.56411218246556	1.23786082466774	0.0475081640533047	NA	NA	0.952939122282918	0.0199166377180776	65.4240013532076
a690	loss_cnaOV36	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.33890189551534	0.567531113016249	0.771370782499095	0.743589750982668	0.563642233545064	1.3359703371627	1.03736069718513	1.36854681319302	0.0479485190648911	NA	NA	0.0101758637237325	0.209149460708027	65.4309973956014
a691	loss_cnaOV55	206	Ruxolitinib	JAK1, JAK2, TYK2	7	25	1.65632149833295	0.0237165266173161	4.84127212244286	4.34291943891719	0.49835268352567	0.311171681413374	0.559166607193795	0.95997052996948	1.60153610785564	0.891241853705601	0.0480337899653688	NA	NA	0.335343091415131	0.00656839160065868	65.4309973956014
a692	loss_cnaOV83	1008	Methotrexate	Dihydrofolate reductase (DHFR)	5	26	-1.6094379124341	NA	1.59493014534872	0.367778463786902	1.22715168156182	0.651640932684685	1.18895774169639	1.08584363177212	1.88317157503612	1.03212388340307	0.0480812639641702	NA	NA	0.401243454714481	0.00807362289575771	65.4309973956014
a693	SMAD4_mut	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.94140741911362	1.75681874284061	1.18458867627301	0.857735742215432	1.37364334902849	0.8890134639861	1.38106484080208	0.862369899079562	0.0481561289727341	NA	NA	0.025242380431853	0.0596613262957604	65.4309973956014
a694	loss_cnaOV83	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	2.56332885965243	1.35257292250441	1.21075593714802	1.54897559759847	0.838719600735121	1.24501816387137	0.781649458535807	1.44357653748264	0.0481664560414682	NA	NA	0.413026391435395	0.216451214637241	65.4309973956014
a695	loss_cnaOV16, loss_cnaOV17	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.72625038099444	2.75327904902792	0.97297133196652	1.20518103676694	0.67222743641497	1.26154907654095	0.80732379807157	1.4473841430148	0.0481768926230719	NA	NA	0.287176775206144	0.204995731249049	65.4309973956014
a696	loss_cnaOV41	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.72625038099444	2.75327904902792	0.97297133196652	1.20518103676694	0.67222743641497	1.26154907654095	0.80732379807157	1.4473841430148	0.0481768926230719	NA	NA	0.287176775206144	0.204995731249049	65.4309973956014
a697	loss_cnaOV42	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.72625038099444	2.75327904902792	0.97297133196652	1.20518103676694	0.67222743641497	1.26154907654095	0.80732379807157	1.4473841430148	0.0481768926230719	NA	NA	0.287176775206144	0.204995731249049	65.4309973956014
a698	loss_cnaOV41	341	EX-527	SIRT1	5	26	2.99573227355399	NA	6.26588297226357	5.67858829939486	0.587294672868707	0.46962040427018	0.531894847090486	1.12133559880222	1.25057315978721	1.10415559782401	0.0482691044743449	NA	NA	0.0898835595912975	0.045252019593716	65.4309973956014
a699	loss_cnaOV70	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-0.78485587171862	-2.9336305964628	2.14877472474418	1.56049309002512	1.66883862104634	1.29301299975706	1.37698445349065	1.28758688685963	0.0483248274555286	NA	NA	0.677944292714274	0.127060383224604	65.4309973956014
a700	NF1_mut	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-1.16764171327318	-2.95568885926729	1.78804714599412	1.08045071228432	1.72896875050233	1.06720330110208	1.65490857256578	1.03416973006286	0.0483676309723698	NA	NA	0.677952195869162	0.0327840483764498	65.4309973956014
a701	loss_cnaOV44	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.5973685145582	4.48406498729898	1.11330352725922	0.699795323552074	0.903454423797398	1.24904183084473	1.59089878110106	1.23227414458804	0.0484885928290042	NA	NA	0.939515731382568	0.0921346517255146	65.4309973956014
a702	TP53_mut	1005	Cisplatin	DNA crosslinker	21	10	1.79175946922805	2.30258509299405	3.26933600992962	2.50745631551353	0.761879694416092	1.02785034926465	1.36958107519123	0.665470869889203	0.741236012578252	0.556286669125967	0.04862324182348	NA	NA	0.07036747422916	0.140551110659695	65.4309973956014
a703	gain_cnaOV49	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	5.19758497869265	6.02218618528567	-0.824601206593016	0.554112476485442	0.671669056506025	1.24053824334239	1.48814769850193	1.22768973589841	0.0486275468326092	NA	NA	0.903104798228022	0.107497899314674	65.4309973956014
a704	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.65874947577294	5.04682609959825	0.611923376174693	0.607606841467046	0.535062302282129	1.12219225809876	1.00710415751282	1.14364883036001	0.0486366464513729	NA	NA	0.0078584639000734	0.0868030833283979	65.4309973956014
a705	loss_cnaOV82	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.55529660815726	1.32164808075	2.23364852740727	1.70028081338996	1.82190901076092	1.23130198643441	1.31369389680631	1.22599345752968	0.0487216040431813	NA	NA	0.769144381119965	0.138380905084382	65.4309973956014
a706	SMAD4_mut	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.69303284849862	4.83347411117228	0.85955873732634	0.655850025674535	0.784649314519611	1.11180043651928	1.31060258241553	1.09546866532674	0.0487225822628738	NA	NA	0.942660106918989	0.0704824297487606	65.4309973956014
a707	loss_cnaOV82	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	4.11376669341168	2.96326555236545	1.15050114104624	0.676043621675985	0.872322873813263	1.33622117490602	1.70181494826328	1.31889369817502	0.0487868479961407	NA	NA	0.21188892582268	0.0803281563739145	65.4309973956014
a708	SMAD4_mut	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.97134900223966	2.8831564205444	1.08819258169526	0.943269650674403	1.16270087250308	0.952918153711792	1.1536389206599	0.935917919587162	0.0488562317187516	NA	NA	0.0704061075330724	0.0980639773200072	65.4309973956014
a709	loss_cnaOV42	255	CP724714	ERBB2	4	28	2.32630161961136	NA	5.26262872848857	4.29398966923569	0.96863905925288	0.638514486054188	0.92377405075291	1.07706858808323	1.51701970810209	1.04856708029783	0.0489558355916574	NA	NA	0.773255395300422	0.0446619617195926	65.4309973956014
a710	loss_cnaOV83	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	5.31635780850182	4.29141951442962	1.0249382940722	0.970175562443779	0.906073566663066	1.12029801924003	1.05644620803525	1.13118661859533	0.0489613983205116	NA	NA	0.0226822666294137	0.0761250733467912	65.4309973956014
a711	loss_cnaOV54	219	AT-7519	CDK9	10	22	2.32630161961136	NA	0.778383291809556	1.82467334890256	-1.04629005709301	1.22323389837035	1.79457971741445	0.636368754011729	0.855347500168957	0.583027907280963	0.0491668020515431	NA	NA	0.2869346721093	0.0659438720524728	65.4870167552497
a712	loss_cnaOV87, loss_cnaOV88	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.81243295513746	4.85018605841927	0.962246896718185	0.690153497882358	0.780110211901647	1.24221499591889	1.39425055392852	1.23347558080614	0.0491733660766438	NA	NA	0.94267509563914	0.123405831231079	65.4870167552497
a713	gain_cnaOV48_(SOX17)	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	4.05509351233884	5.02592000269914	-0.9708264903603	0.953692712825807	0.759694100961531	1.25481741519584	1.01796572135245	1.27791763702198	0.0493346209482988	NA	NA	0.942680421278093	0.214800950057546	65.4870167552497
a714	loss_cnaOV59	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	1.24491684063663	0.553408592909669	0.691508247726961	0.642152070078649	0.567914115855718	1.20101719875027	1.07686057547438	1.21762820895025	0.0493444807533276	NA	NA	0.0102329444726918	0.11622339960563	65.4870167552497
a715	MLL2_mut	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	-0.209406702392893	2.11138644420036	-2.32079314659326	1.66465830823467	1.17063750435183	1.92020262787051	1.39415586677028	1.98250366827112	0.0494229399234993	NA	NA	0.0253417473330841	0.130864504951113	65.4870167552497
a716	loss_cnaOV58	255	CP724714	ERBB2	5	27	2.32630161961136	NA	5.15343238818497	4.27833569302329	0.875096695161678	0.604090093185554	0.9376177588238	0.971989665051913	1.44861951062137	0.933319241157983	0.0494558574120857	NA	NA	0.773321240082092	0.0269899930322458	65.4870167552497
a717	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	282	EKB-569	EGFR	7	25	0.916290731874155	2.99573227355399	2.62711117193648	1.41942741192628	1.20768376001019	1.11587399853085	1.46807321594964	0.859735376173971	1.08227610070691	0.822631832588124	0.0494864483742055	NA	NA	0.297292659301532	0.035947605159601	65.4870167552497
a718	loss_cnaOV56	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	2.219284563137	0.729594176825717	1.48969038631128	2.92121514134355	0.931047083319173	1.26904764376064	0.509955725351379	1.60001616781887	0.0496909765363367	NA	NA	0.835245740013477	0.470602137103392	65.6119195388843
a719	gain_cnaOV18_(CCNE1)	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	0.732412548615166	-0.898783725042005	1.63119627365717	1.60893957392429	1.26750301313388	1.22267463184884	1.01383314830065	1.28693680153396	0.049749251629728	NA	NA	0.898448712160227	0.132653242180295	65.6119195388843
a720	loss_cnaOV20	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	3.76300774896603	1.72317983603801	2.03982791292802	2.8013047114796	1.6589432373867	1.10117005823082	0.728170664393956	1.22959476066301	0.0498850117252877	NA	NA	0.110636450508461	0.181375203017281	65.6119195388843
a721	gain_cnaOV49	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	2.53843014053174	3.81061202386982	-1.27218188333808	0.758223120229951	1.19853742225714	1.08259800714964	1.67784633493141	1.06144527464336	0.0499999191995274	NA	NA	0.173007526624035	0.0774837543087238	65.6119195388843
a722	PTEN_mut	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	2.58956192174055	4.17409210111787	-1.58453017937733	1.76857971000749	0.921183684322347	1.5216405351877	0.895933709072473	1.72010230570134	0.0500211383191463	NA	NA	0.0656124657754331	0.170206707897191	65.6119195388843
a723	loss_cnaOV20	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.65602071800148	5.04733142511148	0.608689292890002	0.607327084665627	0.535709331205597	1.11522080307302	1.00224295648715	1.13623052172746	0.0502239042896557	NA	NA	0.00791048824057616	0.0879599070759354	65.6119195388843
a724	loss_cnaOV87, loss_cnaOV88	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	10.5662152409347	8.56371860627084	2.00249663466383	1.00826938378637	1.64701860963375	1.24292381827886	1.98607303451368	1.21583121341241	0.050388885127599	NA	NA	0.91672630840671	0.0498832927002858	65.6119195388843
a725	loss_cnaOV33_(ZFHX3)	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	10.2886118883794	8.53067848684703	1.75793340153242	1.08488686128315	1.66229510418994	1.09040632669955	1.6203840826805	1.0575338861923	0.0504667765036295	NA	NA	0.916730210436595	0.0354647951967295	65.6119195388843
a726	gain_cnaOV51_(MYC)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.62016603522362	3.69220683637922	0.9279591988444	0.604735374332922	0.844030205614587	1.13977114181954	1.53448803928168	1.09943837634187	0.0505814004797701	NA	NA	0.934298374149862	0.0428025645096441	65.6119195388843
a727	loss_cnaOV85	1010	Gefitinib	EGFR	7	23	-0.693147180559945	NA	1.73272708820568	0.679725675550976	1.05300141265471	0.494243731400861	1.32313618133492	0.881215409541634	2.13053063853765	0.795837516583007	0.0505847741294762	NA	NA	0.954608208822096	0.00392542075292727	65.6119195388843
a728	PIK3R1_mut	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-1.62877765132317	-0.581752199470008	-1.04702545185316	0.67626187029743	0.869167898271122	1.23652268007515	1.54825445266145	1.20462968539889	0.0508439029000715	NA	NA	0.0317321002641649	0.0201078596905957	65.6119195388843
a729	gain_cnaOV96	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-1.52602031462867	-3.58024992987687	2.0542296152482	0.921192179937515	1.76232590247823	1.21209005782738	2.22996857766155	1.16563548907696	0.0508511459570649	NA	NA	0.116541717222677	0.00905609592872065	65.6119195388843
a730	gain_cnaOV26	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	5.1800031362697	4.35371887156089	0.826284264708806	0.610334076385003	0.707142502781574	1.17854634214744	1.35382292531145	1.16848338412496	0.050863792689815	NA	NA	0.499001914165165	0.12952175578873	65.6119195388843
a731	loss_cnaOV20	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	6.1954810078943	4.37806415154953	1.81741685634478	1.75902209768821	1.29101111510202	1.31208182663319	1.0331972854311	1.40774686994167	0.0508700004351446	NA	NA	0.0863825351810397	0.127187309535619	65.6119195388843
a732	loss_cnaOV87, loss_cnaOV88	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.76583583961635	3.71675432566254	1.04908151395382	1.02668423264039	0.787610081867325	1.28972941409392	1.02181516049567	1.33198080891318	0.0509225870215673	NA	NA	0.934317277013903	0.212165830761834	65.6119195388843
a733	PIK3R1_mut	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	3.4712944890485	4.42229454416819	-0.951000055119689	0.576613073150584	0.754202522947037	1.28893914082274	1.64928632284293	1.2609345980489	0.050958203159215	NA	NA	0.197303791634174	0.0347253632958283	65.6119195388843
a734	loss_cnaOV43_(NF1)	1007	Docetaxel	Microtubules	5	26	-4.38202663467388	NA	-3.40849190500238	-4.88705250095287	1.47856059595049	1.40012072964561	1.30458030520402	1.12167666832444	1.05602364470721	1.13336112008778	0.0509923945893636	NA	NA	0.112880817890953	0.0762763938791034	65.6119195388843
a735	loss_cnaOV34	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	4.84536088100338	5.66715041317309	-0.821789532169714	1.86356617465483	0.69548406565639	0.874910062399679	0.440976845011648	1.18160799470527	0.0510084160211256	NA	NA	0.275607871768854	0.38284262004281	65.6119195388843
a736	gain_cnaOV26	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	2.40592829714581	1.09707248003639	1.30885581710942	1.40551687888008	1.17032082706998	1.10274966078052	0.931227391699714	1.11837351505251	0.0510322961681122	NA	NA	0.239850077748626	0.24374069984729	65.6119195388843
a737	TP53_mut	1243	piperlongumine	Increases ROS levels	22	10	2.30258509299405	NA	1.75759227239816	1.29961453788621	0.457977734511951	0.606854947353854	0.751285391255524	0.700760195952833	0.754674138373476	0.609592226659157	0.05104022610503	NA	NA	0.1828332847784	0.111717935007501	65.6119195388843
a738	loss_cnaOV56	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	4.27914012197378	1.81046461903225	2.46867550294153	3.82011377557939	1.63381513829231	1.32634813531952	0.646230884201116	1.51098826610325	0.05104505974574	NA	NA	0.110867024224629	0.379336879064285	65.6119195388843
a739	loss_cnaOV59	255	CP724714	ERBB2	4	28	2.32630161961136	NA	5.25458013968456	4.29513946763626	0.959440672048298	0.646808062738669	0.924377126325376	1.06547851287562	1.4833468030468	1.03793207850383	0.0512509419342785	NA	NA	0.773551819110755	0.0480362639214393	65.6119195388843
a740	gain_cnaOV19	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	0.975447077664705	-0.842402932135221	1.81785000979993	1.87846616550512	1.24511860078629	1.36136528728055	0.967731036726499	1.45998140952353	0.0513910364742289	NA	NA	0.898625405440394	0.23024047912866	65.6119195388843
a741	TP53_mut	345	KIN001-270	CDK9	22	10	2.99573227355399	NA	5.01007638690799	5.5883898767684	-0.578313489860406	0.824986966317568	0.415389616333978	0.795736842578368	0.700997122950657	1.39221941791495	0.0514289380096704	NA	NA	0.304985057174358	0.0132877295688602	65.6119195388843
a742	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	6.65054687267522	5.59049912349218	1.06004774918303	0.423745229834193	1.34257562294662	0.871966994434458	2.50161576945141	0.789562785935658	0.0514474328542494	NA	NA	0.547455820113293	0.00201304378912844	65.6119195388843
a743	loss_cnaOV82	290	KIN001-260	IKK	3	28	2.99573227355399	NA	3.92426571639996	4.9494586395674	-1.02519292316744	0.826061045957359	0.855874541575732	1.20066837336765	1.24106193868432	1.19783084245032	0.0514513080342184	NA	NA	0.645329916761622	0.153314399677419	65.6119195388843
a744	loss_cnaOV16, loss_cnaOV17	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	3.29713877128891	2.34123813798277	0.95590063330614	0.849106214323034	0.666391460973487	1.38455720153375	1.12577274454203	1.43444310032083	0.0514955614492411	NA	NA	0.72120232670416	0.180817329373331	65.6119195388843
a745	loss_cnaOV20	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-0.736656024770226	-3.02798777657327	2.29133175180304	2.65628685886645	1.51612354083463	1.29345612716341	0.862607042667389	1.5113093953687	0.0515170444892549	NA	NA	0.293316726731368	0.182524726853513	65.6119195388843
a746	loss_cnaOV102	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.9737554243756	4.62583676866267	1.34791865571293	0.34559224277312	1.20670953916015	1.15415130872814	3.90031513698596	1.11701997205645	0.0517077892524063	NA	NA	0.396109815061697	0.00142470530696746	65.7069468821477
a747	gain_cnaOV96	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-2.71647171464491	-4.25878051674961	1.54230880210471	0.861902621494194	1.49404353858528	1.06988709017515	1.78942349592923	1.03230512516732	0.0517373731720516	NA	NA	0.855460670147817	0.0241238662522477	65.7069468821477
a748	BRCA1_mut	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-0.862224214353721	-2.20226665041516	1.34004243606144	0.187000966329284	1.58689831714163	0.891115762254862	7.16596530149366	0.844441273638224	0.0517994095237018	NA	NA	0.0278773569377912	0.000235912649693375	65.7069468821477
a749	loss_cnaOV36	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.4368031287292	5.26879896184387	-0.831995833114665	0.578522006295656	0.74626664256177	1.1300090437339	1.43814033703235	1.11487742539129	0.0521555256562039	NA	NA	0.305180518969652	0.113170489317505	65.995174788106
a750	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.6393091954436	4.58646730071014	1.05284189473347	0.388801201693349	1.25259601784346	0.89837832622514	2.70791831441883	0.840527895455154	0.0522273540686943	NA	NA	0.396251525888235	0.00204018533587837	65.995174788106
a751	gain_cnaOV95_(MECOM)	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-1.80021306400065	-2.51404208109121	0.713829017090561	0.67718626816647	0.694168280217285	1.03421988935017	1.0541102952712	1.02832272437905	0.052593383356741	NA	NA	0.639371462161074	0.082966105821218	65.995174788106
a752	PIK3R1_mut	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	0.625876876815516	2.58027820707024	-1.95440133025473	1.11151278695521	1.71997436190695	1.18155796910127	1.75832554802042	1.13629678066124	0.0525976105276391	NA	NA	0.0918066389588463	0.0111329238454238	65.995174788106
a753	loss_cnaOV59	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	1.87441288853982	3.89942125561863	-2.02500836707881	4.56638211312469	1.33921188898471	1.05284787642569	0.443460121582584	1.51208959816958	0.0527274856551086	NA	NA	0.732535102100839	0.44152013464668	65.995174788106
a754	PIK3R1_mut	310	YM201636	FYV1	5	27	1.63315443905142	NA	3.05925541453117	2.22685382288011	0.832401591651055	1.05415980223182	0.774375433211705	1.01856070160834	0.789635110244893	1.07493285033422	0.0527756235099836	NA	NA	0.630791083191327	0.155120225920873	65.995174788106
a755	loss_cnaOV16, loss_cnaOV17	1039	SL 0101-1	RSK, AURKB, PIM3	6	27	2.30258509299405	NA	5.50785611360282	4.81095347912495	0.696902634477865	0.557071017223587	0.813127604663762	0.896277152907988	1.25101219221777	0.857064291607763	0.0528755036248855	NA	NA	0.942792825347447	0.0293325655081704	65.995174788106
a756	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.69603891411023	5.87234079174391	0.823698122366317	0.683335353597636	0.663514334100407	1.23899603502883	1.2054083226189	1.24141722346223	0.0529090625829705	NA	NA	0.903335385866632	0.162695729944893	65.995174788106
a757	loss_cnaOV102	304	SB52334	ALK5	3	29	2.99573227355399	NA	5.40558717849392	4.25916323132067	1.14642394717325	1.11446453366776	1.00652749524779	1.1305055416675	1.02867692289885	1.13898920057918	0.0529416179848835	NA	NA	0.323609967149225	0.210218646914841	65.995174788106
a758	loss_cnaOV84	1072	BMS-708163	g-secretase	6	27	1.6094379124341	NA	4.44107805396541	3.70810904537609	0.732969008589318	0.973808967788676	0.788777682375644	0.892291888185204	0.752682541272692	0.929246636874611	0.0530861159060664	NA	NA	0.919266717749343	0.131691100230127	65.995174788106
a759	loss_cnaOV44	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.81682489669973	3.69748762122681	2.11933727547292	1.44199064225005	1.61494115834021	1.3216018760831	1.46973025578443	1.31233095678304	0.0531134372296668	NA	NA	0.124228426513106	0.11114504257863	65.995174788106
a760	loss_cnaOV43_(NF1)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	2.88782910227045	1.53242405355499	1.35540504871546	1.07950181104118	1.7072470353681	0.826563688222206	1.25558385808373	0.79391266795975	0.0532212464738325	NA	NA	0.203672415503447	0.0473460609226329	65.995174788106
a761	loss_cnaOV54	1030	KU-55933	ATM	11	22	2.30258509299405	NA	4.66493162635243	3.89402630397438	0.770905322378056	0.811228098754342	1.03455178441246	0.796260810666381	0.950294157169602	0.745158757631325	0.0532726737976812	NA	NA	0.505928389599918	0.0275288138900295	65.995174788106
a762	loss_cnaOV81_(RB1)	1248	FK866	NAMPT	4	28	0	NA	1.006480492409	-2.09619178375819	3.1026722761672	1.47413531387983	2.66474095120906	1.20697610764546	2.10474048545867	1.16434292600166	0.0532941348255733	NA	NA	0.0338284112827686	0.0122094490104345	65.995174788106
a763	loss_cnaOV83	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.86094585033415	0.685605761692076	1.17534008864207	2.05460504357313	0.973863358745759	0.998777258220665	0.572051593233733	1.20688398232355	0.0533702584478068	NA	NA	0.83558560734323	0.273378216419209	65.995174788106
a764	gain_cnaOV72_(ASXL1)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	6.05015828815479	4.76017761722857	1.28998067092622	0.269896151442376	1.16726690151829	1.21087664325821	4.77954451752024	1.10512914334186	0.0535408348334416	NA	NA	0.77855295627709	0.00113689717595894	65.995174788106
a765	loss_cnaOV87, loss_cnaOV88	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	4.46062385908647	2.6556501601871	1.80497369889937	1.23006578394801	1.49463999153315	1.22040173327431	1.46737981208301	1.20763107445553	0.0535626346226343	NA	NA	0.966982990971488	0.110449766385056	65.995174788106
a766	loss_cnaOV83	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	5.10101411237801	4.38056976548143	0.720444346896584	0.601667467426022	0.66093887706031	1.10228274450557	1.19741283333583	1.09003172895645	0.0535819354998585	NA	NA	0.0659153891708014	0.0521672812835434	65.995174788106
a767	gain_cnaOV19	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	6.39826597194449	5.65697867092543	0.741287301019068	0.24880771946652	0.583183008662396	1.30724890958428	2.97935812686397	1.27110579356436	0.053733709920284	NA	NA	0.16750476970645	0.00995721770093492	65.995174788106
a768	loss_cnaOV36	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	3.01799666229476	1.23663514255586	1.7813615197389	2.5533402631085	1.24470419694306	1.29504257558661	0.697659276155473	1.43115249720684	0.053742797221582	NA	NA	0.449404416388424	0.349982987164105	65.995174788106
a769	loss_cnaOV87, loss_cnaOV88	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-1.26287377687754	-3.53507885837705	2.27220508149951	1.78875714229129	1.69540442836789	1.33501516926198	1.27027030544178	1.3402141951976	0.0537725498549809	NA	NA	0.117135955509395	0.148665790301074	65.995174788106
a770	gain_cnaOV48_(SOX17)	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	0.42244803734834	1.86289345326468	-1.44044541591634	1.72135440510491	1.53790464484405	0.928568976298994	0.836809323893154	0.936628561949891	0.0537816857444858	NA	NA	0.0307953372822102	0.281014852237484	65.995174788106
a771	loss_cnaOV42	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	5.54755623551314	3.65888530157027	1.88867093394286	1.29469962635355	1.63248746450231	1.1797906736275	1.45877151387013	1.15692829195393	0.0538622060852674	NA	NA	0.124381696578908	0.0513886216853617	65.995174788106
a772	PIK3CA_mut	1268	XAV 939	TNKS1 (tankyrase-1)	7	25	1.6094379124341	NA	2.5407200490263	2.94410259819007	-0.403382549163771	0.837621059510241	1.11755663830805	0.377890543718724	0.481581193051223	0.360950430015324	0.0538882193784145	NA	NA	0.278968383256296	0.317366037403446	65.995174788106
a773	SMAD4_mut	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	1.57041208105699	3.56179303606707	-1.99138095501007	2.25055900416609	1.51209420656424	1.26665773697814	0.884838367411723	1.31696884120393	0.0540305765266664	NA	NA	0.609282045934196	0.262352150657456	65.995174788106
a774	PIK3R1_mut	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-5.44893475912724	-3.43075800176988	-2.01817675735736	1.01717169388411	1.65097887000104	1.2636354418503	1.98410629148642	1.22241222709052	0.0541612558915221	NA	NA	0.217544223908833	0.0163618111435043	65.995174788106
a775	TP53_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	12	7	2.07944154167984	NA	3.0973847442914	4.0933867257782	-0.996001981486796	1.11364268035639	0.768953876600422	0.990484024306651	0.894364053259932	1.2952688214411	0.0542584860859107	NA	NA	0.748100405219779	0.0350740298871501	65.995174788106
a776	gain_cnaOV4_(KRAS)	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.99711505307523	2.22453049555686	0.772584557518365	0.605207764788045	0.949435489373691	0.866816346122224	1.27656088118588	0.813730438945369	0.054263001460659	NA	NA	0.719482009670912	0.0199087811409311	65.995174788106
a777	loss_cnaOV16, loss_cnaOV17	1218	JQ1	BRD2, BRD3, BRD4	6	25	0	NA	2.87325643310538	2.15496047280362	0.718295960301754	0.630802793430836	0.899948568579677	0.835638233149699	1.13870129901464	0.79815223378308	0.0544508227246764	NA	NA	0.571678518240308	0.0440110774899298	65.995174788106
a778	loss_cnaOV40	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.95802326615387	2.23547619589484	0.722547070259029	1.35645923303745	0.741652610128907	0.803805554390101	0.532671423262064	0.974239233289346	0.0544762360423224	NA	NA	0.719512767580796	0.217685708372042	65.995174788106
a779	loss_cnaOV102	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	5.25184346462063	4.17719163888749	1.07465182573314	1.24632592817947	0.806854098836127	1.2743294550517	0.862255852530409	1.33190353408789	0.0544929534559532	NA	NA	0.496962614401703	0.271542103453782	65.995174788106
a780	gain_cnaOV49	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	2.87148223770341	4.00412550192671	-1.1326432642233	0.673899557979545	1.0501481515003	1.09962181962459	1.68073008924228	1.07855569007586	0.0545335573985766	NA	NA	0.289587429125459	0.0775531264248353	65.995174788106
a781	loss_cnaOV58	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.57257434694755	4.82428603154474	0.748288315402801	0.606836502636367	0.799952735431866	0.962139517053879	1.23309707334991	0.935415659274954	0.0545652886829983	NA	NA	0.942843618071511	0.0480263468506515	65.995174788106
a782	loss_cnaOV43_(NF1)	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.51088392681643	2.17701181004934	1.33387211676709	1.29886120562683	1.20993013404253	1.09175484298562	1.02695508264362	1.10243730545866	0.0546202950241945	NA	NA	0.0916749729851691	0.0823850339327238	65.995174788106
a783	gain_cnaOV48_(SOX17)	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-1.1119847993143	0.0451099740704502	-1.15709477338475	1.3080948654816	0.872243127335013	1.27456715562952	0.884564876690914	1.32657367782312	0.0548127990275519	NA	NA	0.525361491394586	0.262492255291044	65.995174788106
a784	loss_cnaOV42	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-2.90992550293488	-4.36537599690974	1.45545049397487	2.62078484017654	0.994227175853671	1.15918244754854	0.555349096828881	1.46390133897233	0.0548293705633483	NA	NA	0.192059242961916	0.34898961242809	65.995174788106
a785	loss_cnaOV52, loss_cnaOV53	1049	PD-173074	FGFR1, FGFR3	9	24	0.693147180559945	NA	3.61926545867235	2.74922658921096	0.870038869461385	0.70224268683911	0.999914745113237	0.933277375870878	1.23894329662235	0.870113050851007	0.0548942213869835	NA	NA	0.071638298516988	0.0108090579314389	65.995174788106
a786	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1049	PD-173074	FGFR1, FGFR3	8	25	0.693147180559945	NA	3.57499616435296	2.79819431817162	0.776801846181335	1.09541112061678	0.909197396229908	0.81389371981823	0.709141829547933	0.854381952040815	0.0550319936257116	NA	NA	0.0716573280924663	0.0986714018330403	65.995174788106
a787	TP53_mut	1203	QL-XII-61	BTK	17	6	2.30258509299405	NA	4.24192018711302	2.89885643808797	1.34306374902505	1.17249884652167	1.92862531196956	0.965995637708548	1.14547127531031	0.696383968772804	0.0551029313975377	NA	NA	0.0498902920942504	0.156991331716152	65.995174788106
a788	PTEN_mut	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	1.80941635489264	3.14886764998427	-1.33945129509163	0.657904089161013	0.931411805838519	1.4742753500625	2.0359370266261	1.43808709176256	0.0553817561294078	NA	NA	0.0717054259186861	0.0163189593378677	65.995174788106
a789	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	0.356697814283356	-1.32166192857461	1.67835974285797	1.73738194629132	1.90941629697342	0.889251579724622	0.966028078305206	0.878991001343344	0.0554205011971211	NA	NA	0.417135886828237	0.0991405167285674	65.995174788106
a790	gain_cnaOV95_(MECOM)	1502	Bicalutamide	ANDR (androgen receptor)	8	24	2.30258509299405	NA	4.87095676940429	4.39790416746062	0.473052601943664	0.666198768210904	0.531554363858387	0.836011811586068	0.710077269001953	0.889942090795612	0.0554289513034232	NA	NA	0.594198256996027	0.0976747387479001	65.995174788106
a791	gain_cnaOV19	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	4.29177101839213	2.0833953708956	2.20837564749653	0.581054701166649	1.73249904816382	1.31281575480255	3.80063295772761	1.27467639871841	0.0554885512680105	NA	NA	0.0922758093242408	0.00218373091826862	65.995174788106
a792	gain_cnaOV19	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-1.54529539154113	-2.47261051754105	0.927315125999917	0.436845401853568	0.703412902196034	1.3686950993384	2.12275354636961	1.31830838346136	0.0555785870093256	NA	NA	0.640357409866842	0.0360164556627105	65.995174788106
a793	loss_cnaOV40	1028	VX-702	p38	7	24	0.693147180559945	NA	3.94462845397628	3.14681861220144	0.797809841774839	0.764470495881737	0.892446050871579	0.919645749755282	1.04361103021333	0.893958621919704	0.0555825480325089	NA	NA	0.492738865507199	0.0389848383649755	65.995174788106
a794	loss_cnaOV42	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	3.09278090967301	2.25712927858551	0.835651631087494	0.817132051226787	0.831595505066555	1.00661454238951	1.02266412121872	1.00487752278148	0.0559498341062514	NA	NA	0.586866480488445	0.129912348446267	65.995174788106
a795	gain_cnaOV49	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	4.68916343121449	5.18932971635772	-0.500166285143229	0.463144425427897	0.579127864106659	0.874221558387685	1.07993588540147	0.863654326000645	0.0559565715725692	NA	NA	0.0080868904118836	0.191359450002373	65.995174788106
a796	loss_cnaOV55	261	TL-1-85	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	4.13268537370456	3.39401440199719	0.738670971707365	0.960506334452754	0.903214354488185	0.807326156485713	0.769043311024306	0.817824659270323	0.056190838271978	NA	NA	0.713097098299045	0.101122262719677	65.995174788106
a797	gain_cnaOV4_(KRAS)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.60382708181813	3.69564661604354	0.908180465774587	0.619216405578749	0.846226786440726	1.11070050451206	1.4666608597454	1.07321167366309	0.0562033221402568	NA	NA	0.934593252008392	0.0497333964582651	65.995174788106
a798	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.78810741371662	4.85261861256136	0.935488801155262	0.72346480288327	0.78108893358531	1.20320081742345	1.29306746842003	1.19767258365989	0.05625266576843	NA	NA	0.942892659005929	0.14252104355636	65.995174788106
a799	loss_cnaOV82	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	5.41549551469601	4.41482579153467	1.00066972316133	1.00864562419896	0.86750134503891	1.1397613996788	0.992092464542283	1.15350797884521	0.0562857469616331	NA	NA	0.503586339840278	0.222155139959273	65.995174788106
a800	loss_cnaOV43_(NF1)	1019	Bosutinib	SRC, ABL, TEC	5	26	0.693147180559945	NA	3.11905730925633	1.45511824066055	1.66393906859578	1.23402976098009	1.51928256199996	1.12185557852046	1.34837839508364	1.09521369507815	0.0562978306844764	NA	NA	0.0310090980312481	0.0347059440451179	65.995174788106
a801	loss_cnaOV82	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	5.27435855708177	4.08558338533944	1.18877517174233	1.18571863361456	0.891757993024179	1.30020181390207	1.00257779378777	1.33306926435376	0.0563426204239665	NA	NA	0.0370767818337501	0.219966708900739	65.995174788106
a802	gain_cnaOV49	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-5.28270809899721	-3.52064574240372	-1.76206235659349	0.653160568974686	1.70941236283725	1.06256568344445	2.69774759881713	1.03080005439346	0.0563436461136023	NA	NA	0.218079972009894	0.012864876407633	65.995174788106
a803	loss_cnaOV83	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.91145147695727	4.36683827574976	0.544613201207508	0.446432007251859	0.5333015171247	1.04221427577084	1.21992418187045	1.02121067298626	0.0564054616432226	NA	NA	0.337583800578455	0.0493520932835652	65.995174788106
a804	loss_cnaOV39	257	NPK76-II-72-1	PLK3	9	23	2.32630161961136	NA	2.63064603041082	3.4641116324695	-0.833465602058679	1.19052958749807	1.17513899279714	0.706768337022207	0.700079704705391	0.709248529039794	0.0564173141497541	NA	NA	0.579673897665774	0.0948540760254551	65.995174788106
a805	gain_cnaOV48_(SOX17)	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	0.559504849656125	2.08208620863667	-1.52258135898055	0.945918795389617	1.29319364477739	1.19606440215933	1.60963220775564	1.17738079299225	0.0564306696314994	NA	NA	0.82967570761101	0.0884633046190474	65.995174788106
a806	loss_cnaOV39	1091	BMS-536924	IGF1R	9	23	1.38629436111989	NA	2.8577712544434	2.21187506393294	0.645896190510467	1.25956483073308	0.729429290445277	0.716226931458933	0.512793128825728	0.885481566165491	0.0565862470225867	NA	NA	0.719810261326317	0.17816153163494	65.995174788106
a807	loss_cnaOV84	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	1.6094379124341	NA	0.247249153976429	1.55002248593911	-1.30277333196269	1.452358068683	1.23864335797825	1.02559518969691	0.89700560767638	1.05177436553578	0.0566381469993288	NA	NA	0.558029017846814	0.117047691215785	65.995174788106
a808	loss_cnaOV20	158	PF-562271	FAK	4	14	0.940007258491471	NA	3.39811244309771	1.97267623009615	1.42543621300156	1.32740422216542	1.25209748537124	1.1254403882193	1.07385240245524	1.1384386836133	0.0566947861345374	NA	NA	0.718057029397833	0.117600479568751	65.995174788106
a809	gain_cnaOV48_(SOX17)	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-4.52196755705218	-2.54703283591105	-1.97493472114113	2.04759527139912	1.65199650542624	1.17466965495476	0.964514202941905	1.19548359494354	0.0568108684034068	NA	NA	0.679379049301489	0.232049830417614	65.995174788106
a810	gain_cnaOV94	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.95270223656122	2.23696608418078	0.715736152380438	0.794320318151504	0.924413318231757	0.795350307196193	0.90106741074691	0.774259888152106	0.056844032378785	NA	NA	0.719845778976382	0.0672144782930462	65.995174788106
a811	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1072	BMS-708163	g-secretase	8	25	1.6094379124341	NA	4.3476165436212	3.67937920799909	0.668237335622115	0.854501226086339	0.809778949841045	0.8148334179414	0.782020335632141	0.825209565836807	0.0568838053303405	NA	NA	0.919423582498305	0.0764288025432252	65.995174788106
a812	KRAS_mut	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	2.94877312474514	5.10041043316154	-2.1516373084164	0.144521855532022	1.44474888405115	1.58440427228587	14.8879717915029	1.4892811700142	0.0569032700733457	NA	NA	0.0881197898439564	2.49999242171991e-05	65.995174788106
a813	BRCA1_mut	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.72049960618984	3.90322589807717	0.817273708112671	0.490229492063738	0.741368887892221	1.12366423290264	1.66712472697667	1.1023846852223	0.0569093903411537	NA	NA	0.501662755853123	0.0793618226459661	65.995174788106
a814	loss_cnaOV57_(ZNRF3)	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	4.73494105578432	3.66756585002307	1.06737520576125	1.17162448185546	0.94912376708183	1.09624527941546	0.911021596331685	1.12459011435673	0.0570550606060427	NA	NA	0.701371378089183	0.164663079944322	65.995174788106
a815	loss_cnaOV36	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	4.08174032983811	2.9664681887228	1.11527214111531	0.708244142128214	0.874859842035522	1.28921365275605	1.57470012778928	1.27480093099304	0.0573289888990766	NA	NA	0.213925066803649	0.0955887717896167	65.995174788106
a816	loss_cnaOV43_(NF1)	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	5.05623332465333	4.08166216656695	0.974571158086381	0.829192478451531	0.930493259290547	1.0615659498224	1.17532561306675	1.04737046545554	0.0575361445641601	NA	NA	0.185625636529143	0.0554736672205109	65.995174788106
a817	loss_cnaOV102	1248	FK866	NAMPT	3	29	0	NA	1.37484112780806	-2.0273093572075	3.40215048501557	1.65368235230554	2.63897426602184	1.31611314278348	2.05731800927327	1.2891942634	0.0575501514424721	NA	NA	0.0341999601718949	0.0466418773340027	65.995174788106
a818	gain_cnaOV96	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.98106536931712	4.77599778636991	1.20506758294721	1.04934465038205	1.17925666233718	1.03637302030756	1.14840017768086	1.02188744947081	0.0575814252849563	NA	NA	0.3456572279648	0.05984738645911	65.995174788106
a819	loss_cnaOV57_(ZNRF3)	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	1.70112466199521	0.62357007227762	1.07755458971759	0.604085659342525	1.02436936768097	1.08799986647851	1.78377780212558	1.05191996531195	0.0575819215183838	NA	NA	0.759000445260592	0.0245947029615262	65.995174788106
a820	loss_cnaOV87, loss_cnaOV88	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.79991411642066	2.69766144584334	1.10225267057732	0.99584208837011	0.907281347893221	1.2069506428884	1.10685487533608	1.21489620957913	0.0576475784784443	NA	NA	0.964286028084855	0.187808410446515	65.995174788106
a821	loss_cnaOV59	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	3.45468575425981	0.980636741213679	2.47404901304613	1.80978055207316	2.22716935949697	1.13021121061889	1.36704365079624	1.11084907059108	0.0577016477322432	NA	NA	0.336512598406445	0.062420722755361	65.995174788106
a822	SMARCA4_mut	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	1.72220692409988	3.7340988322126	-2.01189190811273	1.74078683121565	1.59986081737626	1.24964098264073	1.15573709085779	1.257541835053	0.0578163736494791	NA	NA	0.681289225986855	0.174716266821487	65.995174788106
a823	loss_cnaOV42	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	5.10017240575356	4.16047851066375	0.93969389508981	1.087641311249	0.812754330716017	1.11301192351273	0.863974074330355	1.1561844207732	0.0578585795336232	NA	NA	0.497709311925628	0.18187049466406	65.995174788106
a824	gain_cnaOV26	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	0.811474415995014	2.40538532800189	-1.59391091200688	0.865479032367052	1.2703835357048	1.29892617008999	1.8416516777392	1.25466905639846	0.0578588477161174	NA	NA	0.879632392454207	0.0561609708927424	65.995174788106
a825	loss_cnaOV57_(ZNRF3)	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	5.29231108102269	4.25792364743284	1.03438743358985	0.764595983033215	0.945092537435628	1.11389387284756	1.35285491493998	1.09448270155271	0.057894274081798	NA	NA	0.487338865326682	0.0642501814619921	65.995174788106
a826	PIK3R1_mut	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	4.29449072262979	3.0579147648339	1.23657595779589	0.815851203787925	1.01745514395343	1.24536517021619	1.51568809613148	1.21536164532133	0.0579483240589002	NA	NA	0.0493605458013535	0.0219838518777988	65.995174788106
a827	loss_cnaOV44	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-2.50897906125743	-4.22592941525167	1.71695035399424	1.71940912059763	1.42271837249379	1.18808856688251	0.998569993276217	1.20680971525286	0.0580985813982039	NA	NA	0.855961868247485	0.22036225228104	65.995174788106
a828	loss_cnaOV44	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.68101233711332	5.8738434494436	0.807168887669716	0.703967980286188	0.663937016582222	1.21088857290072	1.14659886567791	1.21573111230462	0.0582270731949177	NA	NA	0.903595068823153	0.177093485380349	65.995174788106
a829	loss_cnaOV57_(ZNRF3)	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	3.91309500414358	4.48001513361127	-0.566920129467693	0.872577287489325	0.569998978799426	0.933845026704016	0.649707639192509	0.994598500267109	0.0585586056120372	NA	NA	0.244892079172052	0.287249081788216	65.995174788106
a830	loss_cnaOV81_(RB1)	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	1.16235689285329	2.65152128388747	-1.48916439103418	0.806425686229663	1.56744251645982	0.98704160876471	1.84662321211093	0.95005997055481	0.0587815126361147	NA	NA	0.189691016903673	0.0533810176267115	65.995174788106
a831	loss_cnaOV42	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	10.2394986196611	8.53795452665715	1.70154409300398	1.05105333007079	1.67263351240597	1.05070305462484	1.61889415534164	1.01728446810588	0.0588362759306964	NA	NA	0.917115191210998	0.0353774409775502	65.995174788106
a832	loss_cnaOV33_(ZFHX3)	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	4.57652658971202	5.2785526043147	-0.702026014602686	0.548831233964473	0.758076044625719	0.9489152270119	1.27912912231983	0.926062786945462	0.059050530327461	NA	NA	0.306903649131056	0.0746350033731863	65.995174788106
a833	gain_cnaOV94	1011	ABT-263	BCL2, BCL2L1, BCL2L2	7	26	0.693147180559945	NA	2.61397736714397	1.50189144003401	1.11208592710996	1.21015662869509	1.73832322776822	0.674256897900848	0.918960323598045	0.639746342535922	0.0590509169778216	NA	NA	0.204964068026491	0.0723026502479059	65.995174788106
a834	loss_cnaOV59	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	2.5166061473221	0.599093403515126	1.91751274380697	2.57562876602365	1.89922383970793	0.967090829380569	0.744483354550857	1.00962967277299	0.0590604457845615	NA	NA	0.387917753797449	0.235046140018576	65.995174788106
a835	gain_cnaOV18_(CCNE1)	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	3.87056233939539	2.76743158696251	1.10313075243288	1.44241548290252	1.17025719786375	0.919081631676543	0.764780165984555	0.942639579099873	0.0590802975217044	NA	NA	0.206413668802877	0.225311063712481	65.995174788106
a836	gain_cnaOV94	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.58135326934179	2.86219313115652	0.719160138185264	0.117976644521681	0.57708368678293	1.3229972394555	6.09578396725041	1.24619731012389	0.0591747829172538	NA	NA	0.833435125424115	0.000340494328226151	65.995174788106
a837	PIK3R1_mut	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	7.60554626461309	8.91906860573627	-1.31352234112318	0.333241610167251	1.21926306192855	1.13289259201184	3.94165164567513	1.07730840221267	0.0591998411416013	NA	NA	0.5057808971545	0.000229422112471762	65.995174788106
a838	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1030	KU-55933	ATM	5	28	2.30258509299405	NA	4.98421543844011	4.00220533518259	0.982010103257518	0.828536462216928	0.992159497453989	1.00968054478637	1.18523462519674	0.989770400603415	0.0592487991293868	NA	NA	0.507193866227601	0.0542499180566071	65.995174788106
a839	loss_cnaOV82	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.05463787846677	3.4566319562235	-1.40199407775672	1.23686299231381	1.16151848085916	1.20168225481833	1.13350798469118	1.20703553224542	0.0592517786687065	NA	NA	0.993243201165982	0.18025330714548	65.995174788106
a840	TP53_mut	1004	Vinblastine	Microtubules	21	10	-2.30258509299405	NA	-2.94572265513531	-4.09106536073486	1.14534270559954	1.85029537273981	1.51435810068858	0.65338304444389	0.619005334215145	0.756322236516417	0.0592530099476148	NA	NA	0.118167221498229	0.0814068098137267	65.995174788106
a841	loss_cnaOV59	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	1.68573525932545	0.399775916588936	1.28595934273651	0.701928810871284	1.17857094744277	1.12946673823929	1.83203670061682	1.09111746350676	0.0592749648269861	NA	NA	0.404194302459623	0.022161274297872	65.995174788106
a842	KRAS_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	0.0810992951519886	1.08993559005171	-1.00883629489973	0.552331394538379	1.29060553445912	0.854594981964904	1.82650543654662	0.781676715281188	0.0594626443348674	NA	NA	0.836095912943573	0.00562117933176724	65.995174788106
a843	loss_cnaOV87, loss_cnaOV88	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.77345515858828	3.70213437888161	2.07132077970667	1.48599755822174	1.61823501564293	1.28696306534907	1.39389245173819	1.279987615942	0.0597663991992381	NA	NA	0.125519264789813	0.123529281726439	65.995174788106
a844	MLL2_mut	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	1.29129000725259	2.19771436932908	-0.906424362076489	0.917091089703564	0.452003451569281	1.82980654574221	0.988368955115982	2.00534831964122	0.0597702138489382	NA	NA	0.0327828625462227	0.226959166313481	65.995174788106
a845	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	3.38564176835788	2.38550938780816	1.00013238054972	0.689843052304916	1.01142748900562	1.02482492089163	1.44979698963127	0.988832507936867	0.0598717400644705	NA	NA	0.369829554565587	0.0264317510350244	65.995174788106
a846	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	2.83087720361408	0.635193387771831	2.19568381584225	3.05911711603454	1.87176523485734	1.10874777164706	0.717750819127991	1.17305513263772	0.0601376879876225	NA	NA	0.388182377135011	0.339033699834748	65.995174788106
a847	loss_cnaOV81_(RB1)	309	Y-39983	ROCK	4	28	2.99573227355399	NA	6.10447477305812	4.80140599951217	1.30306877354594	0.467320009292599	1.21852361778456	1.1181294581422	2.78838643249719	1.06938327212328	0.0601928312775144	NA	NA	0.346270505481157	0.0023723506758182	65.995174788106
a848	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	326	GSK690693	AKT	5	27	2.32630161961136	NA	5.37674408951132	3.92511393746047	1.45163015205085	0.380431843688512	1.45914065534199	1.06309886796683	3.81574301976521	0.994852790055814	0.0602231088652774	NA	NA	0.0770893091029784	0.000155933962693949	65.995174788106
a849	KRAS_mut	1164	XMD8-92	MAP2K5 (ERK5)	6	17	2.30258509299405	NA	3.32932391628551	2.77890352692912	0.550420389356386	0.841684837566665	0.819061830657622	0.667577127416733	0.653950700772592	0.672013233621759	0.0604721579425762	NA	NA	0.291731579328426	0.200395418805627	65.995174788106
a850	loss_cnaOV43_(NF1)	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.89005852958492	2.43458337554526	1.45547515403966	1.3808580289889	1.66405675423997	0.892775271018354	1.05403678255424	0.874654755813554	0.0605262484691986	NA	NA	0.621820006137399	0.0783779776538666	65.995174788106
a851	NF1_mut	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	0.991971033307705	1.70340325851396	-0.711432225206257	0.56243588636669	0.653625464469264	1.10284720945842	1.26491257483956	1.08844019071982	0.0606587526933697	NA	NA	0.184978264415767	0.0775811662864404	65.995174788106
a852	loss_cnaOV43_(NF1)	1053	MK-2206	AKT1, AKT2	5	27	1.38629436111989	0.693147180559945	2.34606835429116	1.11800699139556	1.2280613628956	0.976804627221768	1.16113232250281	1.07887342788815	1.25722312187285	1.05764118274524	0.0607166777933154	NA	NA	0.0807031116232056	0.0444894647600789	65.995174788106
a853	loss_cnaOV42	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	4.28707607371233	3.37071525842081	0.916360815291517	1.31734368457892	0.794020695349119	1.06712620622168	0.695612561868717	1.15407673963536	0.0607248071654531	NA	NA	0.78320018479614	0.259800404167668	65.995174788106
a854	loss_cnaOV44	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.37136242345409	4.31614270283419	1.05521972061991	0.735263915085215	0.914938991246022	1.16718514214342	1.43515776984324	1.15332249550633	0.0608136952073123	NA	NA	0.774648479666197	0.114438940697779	65.995174788106
a855	loss_cnaOV83	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	3.14507751957882	2.31806109621838	0.827016423360446	0.824758664536294	0.666064951721714	1.18704590823986	1.00273747815116	1.24164530984957	0.0610768066236159	NA	NA	0.723627566921432	0.135958369447292	65.995174788106
a856	SMAD4_mut	254	AC220	FLT3	3	29	0.0237165266173161	NA	1.85834222655894	2.57831711312375	-0.719974886564811	0.495623722456612	0.603000683296234	1.20711243967766	1.45266429741534	1.19398685027876	0.0611195966859007	NA	NA	0.850156009844662	0.112246800322652	65.995174788106
a857	gain_cnaOV48_(SOX17)	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	3.48836893879325	4.53740288085068	-1.04903394205742	0.942422207091413	0.970933513561264	1.08246100125752	1.1131252364002	1.08043849285797	0.0612337077422298	NA	NA	0.34973722706832	0.184635993699217	65.995174788106
a858	loss_cnaOV44	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.56736891316405	3.46062309456194	1.10674581860211	1.66435666933182	0.779496041551638	1.28041372937692	0.664969137322249	1.41982224361147	0.0612692618444482	NA	NA	0.123053380241524	0.368346243780932	65.995174788106
a859	loss_cnaOV59	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	4.54899708163965	2.60060328296936	1.94839379867028	1.1855518114635	1.79723153098179	1.11608800971102	1.6434488816352	1.08410839954823	0.0613025240632132	NA	NA	0.3201419899404	0.033952667175362	65.995174788106
a860	loss_cnaOV16, loss_cnaOV17	1024	CEP-701	FLT3, JAK2, NTRK1, RET	6	25	0.693147180559945	NA	1.08141249724259	-0.455182964027686	1.53659546127028	1.51268527117695	1.4922242292068	1.02729259443822	1.01580645395901	1.02973496287958	0.0613152146058011	NA	NA	0.0829924854875606	0.0574584800155001	65.995174788106
a861	PIK3CA_mut	299	OSI-027	MTORC1/2	6	26	2.99573227355399	NA	0.529869006860484	1.76209500480995	-1.23222599794947	2.32742926951281	1.76410186654535	0.659010284133801	0.529436496348352	0.698500478525394	0.061334910453845	NA	NA	0.770647802043144	0.26606392708531	65.995174788106
a862	ARID1A_mut	262	VX-11e	ERK	8	24	1.63315443905142	NA	3.53656524289822	2.63351503543077	0.903050207467445	0.702452552595984	1.14077764628216	0.856036870692257	1.2855675506198	0.791609311780012	0.0614377159759704	NA	NA	0.364897935394736	0.0152770284383677	65.995174788106
a863	loss_cnaOV59	272	AR-42	HDAC	4	26	1.63315443905142	NA	1.7776990480914	0.0670052713601182	1.71069377673128	2.18791187187091	1.70090263633729	0.972238360447783	0.781884224280224	1.00575643789645	0.0614557333554781	NA	NA	0.460139934194419	0.217108610855159	65.995174788106
a864	gain_cnaOV19	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	0.212203644816484	-2.61950236511147	2.83170600992795	2.14867502801871	2.50375285598601	1.14893497713021	1.31788473035826	1.13098463498818	0.0615784766486361	NA	NA	0.370192756403455	0.130768974760419	65.995174788106
a865	PIK3R1_mut	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	1.20060378945141	2.5895618345788	-1.3889580451274	0.673883446602557	1.27397746341697	1.14473979626114	2.0611250389514	1.09025323054149	0.0616165589078887	NA	NA	0.0927282217816454	0.00474673017113656	65.995174788106
a866	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.800147810972775	-0.187433424085602	0.987581235058376	0.976669991861923	0.943107954990755	1.04272230889282	1.01117188332535	1.04715608624896	0.0617192027891286	NA	NA	0.149992653307053	0.212706104166989	65.995174788106
a867	gain_cnaOV96	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	3.3951594240979	1.80436030154405	1.59079912255385	1.47674585317678	1.38914822958742	1.13223851406743	1.07723283538039	1.14516153760374	0.0618453174609661	NA	NA	0.942180513072133	0.116343250404715	65.995174788106
a868	loss_cnaOV40	1375	Temozolomide	DNA akylating agent	8	25	3.40119738166216	NA	6.34641570812635	5.81948059318548	0.526935114940871	0.59767885593282	0.688241895070556	0.78780506144009	0.881635864662577	0.765624875083856	0.0619904770599824	NA	NA	0.903763681720167	0.0561312755105255	65.995174788106
a869	loss_cnaOV85	192	LFM-A13	BTK	6	13	2.77258872223978	NA	5.15301407630438	4.52757965725741	0.625434419046962	0.527587854346971	0.666486563083319	0.994604975646984	1.18546022978695	0.938405143763978	0.062033374677982	NA	NA	0.952354769672473	0.0473162205094719	65.995174788106
a870	loss_cnaOV102	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.5642354286471	3.46093644301363	1.10329898563347	1.66872122409743	0.779312006628064	1.27585393457501	0.661164351301529	1.41573461752147	0.0622264584942887	NA	NA	0.12320995065641	0.370549684459232	65.995174788106
a871	loss_cnaOV81_(RB1)	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.73524622956706	4.61124855101531	1.12399767855176	0.514630064294919	1.22916607085928	0.95613432971883	2.1840886425703	0.914439232581479	0.062273176635361	NA	NA	0.398729418884104	0.00994130793066242	65.995174788106
a872	loss_cnaOV84	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	3.01086318935344	2.18048182873412	0.830381360619322	0.614863139327253	0.996202886764492	0.901808814773012	1.35051413478433	0.833546430804138	0.0623803617464789	NA	NA	0.363652075878533	0.0511721202178269	65.995174788106
a873	loss_cnaOV41	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	0.05002395829681	-0.881538201187861	0.931562159484671	1.33526115554244	0.771339801559067	1.07693255568455	0.697662892100109	1.20771955187811	0.0624171654852276	NA	NA	0.0326556548022858	0.196572985038777	65.995174788106
a874	loss_cnaOV44	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.25843496866808	4.41285730297886	0.845577665689224	0.784631081294052	0.650288855294376	1.28160144540684	1.07767546538515	1.30031086770885	0.0624476964858227	NA	NA	0.0670231081738948	0.196811131085904	65.995174788106
a875	gain_cnaOV19	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.7321446968907	3.98846078166611	1.74368391522459	0.276312367269435	1.41933450695471	1.26992352409388	6.31055327872569	1.2285221747802	0.0624777129787605	NA	NA	0.0773885515237777	2.20613346806202e-05	65.995174788106
a876	loss_cnaOV87, loss_cnaOV88	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	3.16492571059656	2.20067047453333	0.964255236063235	0.816979742615799	0.862157695961988	1.12237778097789	1.18026823159151	1.11842095776612	0.0624879061259116	NA	NA	0.573265540622074	0.16681197312601	65.995174788106
a877	gain_cnaOV18_(CCNE1)	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-0.218377242446634	-2.6934611958365	2.47508395338987	1.95434622979808	2.57347593432557	0.999833850473262	1.26645111068451	0.961766892931334	0.0625104590151119	NA	NA	0.370566139552591	0.0800698849033503	65.995174788106
a878	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	3.32299313115232	1.38345737545149	1.93953575570084	1.27286921093504	1.54337363386012	1.27030093225477	1.52375101780965	1.25668581680372	0.0625347632323513	NA	NA	0.0642476182250321	0.102190007224918	65.995174788106
a879	MLL2_mut	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	2.93343848246145	4.44533580152655	-1.5118973190651	1.37071555981256	1.23278443923846	1.21716603610538	1.10299858219443	1.22640850333822	0.0626097487497173	NA	NA	0.346166465501093	0.188991539219604	65.995174788106
a880	loss_cnaOV16, loss_cnaOV17	173	FH535	unknown 	3	15	3.46573590279973	NA	3.60091223151683	2.27600921913114	1.32490301238569	1.4616291505236	1.34880915173629	0.971748096474002	0.90645634148106	0.982276114215402	0.0626461019733652	NA	NA	0.0874051716427056	0.251174550545495	65.995174788106
a881	loss_cnaOV33_(ZFHX3)	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	1.21971228557849	0.55700924363226	0.66270304194623	0.652258995833128	0.571077460631242	1.14316810993638	1.01601211509511	1.16044335073864	0.062672383373416	NA	NA	0.0107144768764813	0.131932411114887	65.995174788106
a882	loss_cnaOV85	1049	PD-173074	FGFR1, FGFR3	7	26	0.693147180559945	NA	3.69918905080295	2.7946347659036	0.904554284899355	0.860668343580156	0.95789008307507	0.962436999092338	1.0509905373499	0.944319500621101	0.0626994284558138	NA	NA	0.0726476255297501	0.0359475918809025	65.995174788106
a883	loss_cnaOV55	1038	NU-7441	PRKDC (DNAPK)	8	25	0.693147180559945	NA	3.17383639802863	2.33327122064756	0.840565177381072	0.895002163071337	0.997462809518529	0.861881316911952	0.939176699301535	0.842703276111928	0.0628362053701851	NA	NA	0.37046970981471	0.0425357773122013	65.995174788106
a884	loss_cnaOV16, loss_cnaOV17	1038	NU-7441	PRKDC (DNAPK)	6	27	0.693147180559945	NA	3.29427684111245	2.36877076495346	0.925506076158996	1.05047115446847	0.961675322468796	0.947736663160173	0.881039019702828	0.962389337165326	0.0628389906929833	NA	NA	0.370470295983505	0.0880561527910151	65.995174788106
a885	RB1_mut	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-0.836843100800549	-2.15712739700794	1.32028429620739	1.38245563549913	1.53103212535308	0.867893553638385	0.955028329520836	0.862349178925896	0.0628734643413182	NA	NA	0.0287264765602235	0.232955282584225	65.995174788106
a886	loss_cnaOV44	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	5.44746070033168	3.57772449658722	1.86973620374446	0.664729588890318	1.51202195639606	1.27007333300836	2.81277715779999	1.2365800614437	0.0629130392772137	NA	NA	0.144269125565444	0.0131780284763479	65.995174788106
a887	loss_cnaOV39	1047	Nutlin-3a	MDM2	10	23	2.07944154167984	1.38629436111989	4.62366353311485	3.36684702902014	1.25681650409471	0.968814289764857	1.61331792349903	0.863258062553933	1.29727288023359	0.779025935178903	0.0629954039147625	NA	NA	0.144283312184838	0.0101197154779303	65.995174788106
a888	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	3.30559259393978	2.28415836532467	1.02143422861512	0.946981698818413	0.739316013197502	1.33229558468555	1.0786208750281	1.38159354103189	0.0629960693041512	NA	NA	0.586108251053389	0.193836439999387	65.995174788106
a889	PTEN_mut	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	1.44576693269983	2.69135842563046	-1.24559149293063	1.42210725131836	0.878400670731126	1.30890132668677	0.875877323440906	1.41802201937514	0.0631227289188899	NA	NA	0.170985421396826	0.177308231932734	65.995174788106
a890	loss_cnaOV39	287	KIN001-244	PDPK1 (PDK1)	9	23	2.99573227355399	NA	3.05587254474444	3.73552489668273	-0.679652351938297	0.655584913312033	0.917110449565434	0.794704933218608	1.03671139792506	0.741080152625396	0.0631508306535045	NA	NA	0.645828596956097	0.0294322278256224	65.995174788106
a891	loss_cnaOV42	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.83979461716149	2.75407660160177	1.08571801555972	1.59340223908862	0.978176588772236	1.05339892229313	0.681383513167852	1.10994070807038	0.0632428821193174	NA	NA	0.281165734339709	0.358952102514745	65.995174788106
a892	loss_cnaOV44	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.83979461716149	2.75407660160177	1.08571801555972	1.59340223908862	0.978176588772236	1.05339892229313	0.681383513167852	1.10994070807038	0.0632428821193174	NA	NA	0.281165734339709	0.358952102514745	65.995174788106
a893	loss_cnaOV44	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.76595462472507	4.85483389146051	0.911120733264561	0.754568514697133	0.781768017277204	1.16804086158782	1.20747250318318	1.16546176503597	0.0633783397019836	NA	NA	0.943083421289366	0.161266079853296	65.995174788106
a894	ARID1A_mut	1047	Nutlin-3a	MDM2	9	24	2.07944154167984	1.38629436111989	2.7389319092726	4.12598874229826	-1.38705683302566	1.6238446566098	1.36780044920351	0.964408095618131	0.854180741599695	1.01407835758013	0.0633786599559024	NA	NA	0.144349073751935	0.0410356867118696	65.995174788106
a895	loss_cnaOV20	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	2.34311814479772	3.41928005702503	-1.07616191222731	0.592194860409987	1.06951464195218	1.05622579131313	1.8172429113658	1.00621522138583	0.0634098236798967	NA	NA	0.0499190595111543	0.00966331094354616	65.995174788106
a896	gain_cnaOV95_(MECOM)	222	BX-912	PDPK1 (PDK1)	9	23	2.32630161961136	NA	2.78669826269107	3.65378546898894	-0.867087206297865	1.02205704946035	1.21116991432305	0.745081228829525	0.848374566523161	0.715908805233575	0.0634140411528873	NA	NA	0.301039888453826	0.0564104365770728	65.995174788106
a897	loss_cnaOV16, loss_cnaOV17	293	MP470	PDGFR	6	26	2.99573227355399	NA	5.17587337778608	3.78925103902433	1.38662233876175	1.04582483665865	1.79287095818161	0.819791289530184	1.32586480083217	0.773408890603099	0.0634268740661371	NA	NA	0.603080400592992	0.0263678629206471	65.995174788106
a898	ARID1A_mut	1017	Olaparib	PARP1, PARP2	9	22	1.6094379124341	NA	3.15796440062053	4.30168430961636	-1.14371990899583	1.30419307209835	0.931754079335329	1.09154109866373	0.876955976430446	1.22749117429323	0.0635126892080443	NA	NA	0.0674619945122447	0.0347800991959872	65.995174788106
a899	loss_cnaOV16, loss_cnaOV17	1377	Afatinib (rescreen)	ERBB2, EGFR	6	27	2.30258509299405	NA	3.73872016751195	2.41430763548593	1.32441253202601	1.27647891920532	1.69412648651375	0.810533816325148	1.03755143316471	0.781767207212168	0.0635432485185335	NA	NA	0.622293094959016	0.0583203718805082	65.995174788106
a900	gain_cnaOV95_(MECOM)	1005	Cisplatin	DNA crosslinker	8	23	1.79175946922805	2.30258509299405	3.70031351684171	2.78817874908364	0.912134767758073	0.534502348345292	1.2614086471858	0.807470564019353	1.70651218012765	0.723108066361401	0.0637007400481343	NA	NA	0.072552958077508	0.0088783001479597	65.995174788106
a901	loss_cnaOV41	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.97786072323645	2.24746073418163	0.730399989054817	0.752869071027384	0.845831584927693	0.875742113520359	0.970155392435094	0.863528865639672	0.0637674127679365	NA	NA	0.588280353724955	0.0983396009364856	65.995174788106
a902	loss_cnaOV83	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	5.04801519898978	3.51550146441653	1.53251373457324	0.728827066737227	1.54715552246046	1.04434815151474	2.10271243277767	0.990536317988296	0.0638825270769052	NA	NA	0.144434907980809	0.00444175686578076	65.995174788106
a903	loss_cnaOV43_(NF1)	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.95959367979211	4.77997402517084	1.17961965462127	0.615252473511767	1.22949604816397	1.01130092430421	1.91729364026475	0.959433465754373	0.0639099926636291	NA	NA	0.347096205063164	0.0075871384367614	65.995174788106
a904	KRAS_mut	1378	Bleomycin (50 uM)	DNA damage	7	25	3.91202300542815	NA	0.635237516212546	2.43576926817475	-1.8005317519622	1.37731753994827	1.95134769305826	0.972818939708049	1.30727424848581	0.922711907451157	0.0639294425787036	NA	NA	0.11312047589596	0.0154803124096658	65.995174788106
a905	loss_cnaOV39	1268	XAV 939	TNKS1 (tankyrase-1)	10	22	1.6094379124341	NA	3.26243555001906	2.67105680898842	0.591378741030633	1.34209139853717	0.885293443741567	0.566702295967455	0.440639692404866	0.668003073118055	0.063940345953964	NA	NA	0.281315552715423	0.225762386487786	65.995174788106
a906	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1039	SL 0101-1	RSK, AURKB, PIM3	8	25	2.30258509299405	NA	5.40512520986484	4.78807515756287	0.617050052301965	0.597239138158172	0.824671687174946	0.791962365399835	1.03317082367523	0.748237222034111	0.0639646137468482	NA	NA	0.94309806158632	0.0347106148769369	65.995174788106
a907	loss_cnaOV43_(NF1)	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.93864953151489	1.2703865373573	1.66826299415759	1.46980903170186	1.8801141882619	0.911256759197084	1.13502023608192	0.887320038630124	0.0640664476644726	NA	NA	0.77092890335674	0.0632776155659299	65.995174788106
a908	gain_cnaOV48_(SOX17)	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	2.63515961362276	3.78968895473428	-1.15452934111152	1.12870260560441	0.99358602695748	1.15089234960171	1.02288178956872	1.16198226402888	0.0642861783255186	NA	NA	0.821820530618007	0.212254699171808	65.995174788106
a909	gain_cnaOV96	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.97079182230149	3.78364299693962	1.18714882536187	0.581648110319759	1.28082780084454	0.964651692225188	2.0410086516214	0.926860601073068	0.0643190456149055	NA	NA	0.553015118239607	0.013455984704368	65.995174788106
a910	loss_cnaOV41	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.92406635854711	2.17281610099951	0.751250257547606	0.665381218642486	0.889633546463087	0.871341129799013	1.12905239357418	0.844449111136095	0.064367635243847	NA	NA	0.57360479733207	0.065364327472753	65.995174788106
a911	BRCA1_mut	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	5.00750418127099	4.4183105955271	0.589193585743888	0.152419248886833	0.711003113378552	0.869804748854673	3.86561139781858	0.828679332983722	0.0643768254344576	NA	NA	0.0672432555278372	0.000722276152199843	65.995174788106
a912	NF1_mut	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	4.35160552563389	2.81815864464713	1.53344688098676	0.627227855337583	1.62040397295923	0.989324766526886	2.44480035116016	0.946336164670303	0.064408435341982	NA	NA	0.646204830816204	0.00541633366493528	65.995174788106
a913	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	299	OSI-027	MTORC1/2	7	25	2.99573227355399	NA	2.72381382717295	1.19707949504044	1.52673433213251	1.35791312143079	1.9200407145167	0.838152940064227	1.12432401457601	0.795157269629468	0.0645602571125364	NA	NA	0.770978322249518	0.0325092695366972	65.995174788106
a914	PIK3R1_mut	263	FR-180204	ERK	5	27	2.99573227355399	NA	5.37655770251167	4.70717403889982	0.669383663611851	0.339569823861482	0.751343084093042	0.942306202665144	1.97126957866818	0.890916117794409	0.0645677814537383	NA	NA	0.752721173366367	0.00712808528369648	65.995174788106
a915	PIK3CA_mut	196	Phenformin	AAPK1 (AMPK) agonist	6	25	8.29404964010203	NA	7.81524730580771	8.98365131454166	-1.16840400873395	0.47405057845681	1.80752856434057	0.705523804343768	2.46472436029398	0.646409706482408	0.0646677636409387	NA	NA	0.917349613196869	0.00805022256785278	65.995174788106
a916	loss_cnaOV42	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	3.01974369136137	2.1864657649362	0.833277926425175	0.727517611287323	0.875235971024882	0.967655638734575	1.14537148447955	0.952060877307665	0.0646897236679223	NA	NA	0.57366184730702	0.099824975836204	65.995174788106
a917	gain_cnaOV18_(CCNE1)	305	TPCA-1	IKK	4	28	2.99573227355399	NA	4.38095176318864	3.17437261832597	1.20657914486267	1.71940117976934	1.09230758732506	1.03105473751295	0.70174381584671	1.10461481625103	0.0647390198874808	NA	NA	0.993260546270332	0.256689615195454	65.995174788106
a918	loss_cnaOV16, loss_cnaOV17	1494	SN-38	TOP1	6	26	-2.99573227355399	NA	-3.19611954450775	-4.41128894839099	1.21516940388324	2.07932501952345	1.01768987047657	0.965614238007034	0.584405704963692	1.19404686942024	0.0647815443213294	NA	NA	0.19415690140842	0.216575528239846	65.995174788106
a919	loss_cnaOV57_(ZNRF3)	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	5.06231387506649	3.94426624358783	1.11804763147866	1.24188137358167	1.04124693279315	1.051769532432	0.9002853696518	1.07375839127755	0.0647873820352896	NA	NA	0.809920753032436	0.168497263241282	65.995174788106
a920	loss_cnaOV59	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	0.136552093522703	-0.861350283305754	0.997902376828457	1.46453223495323	0.777871930135077	1.14914571878233	0.681379592071815	1.28286204729765	0.0647928681865108	NA	NA	0.032824579129443	0.267412411238577	65.995174788106
a921	gain_cnaOV96	1028	VX-702	p38	4	27	0.693147180559945	NA	4.15872486351599	3.20374616357795	0.954978699938042	0.441453733196765	0.909619789316762	1.09401557960028	2.16325886072503	1.04986579134932	0.0648551593986555	NA	NA	0.494730714788589	0.0102274477686402	65.995174788106
a922	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.59919432935664	3.65317171766667	0.946022611689966	1.04286544617912	0.966801137958412	0.968010817814274	0.907137747401675	0.978507962545096	0.0650349301293419	NA	NA	0.70244803106207	0.114421625147632	65.995174788106
a923	loss_cnaOV20	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	2.17820958628616	1.51007879408115	0.668130792205013	0.731322300098564	0.627357474834172	1.04038998452397	0.913592805955685	1.06499215998282	0.0650732691712009	NA	NA	0.185846874211476	0.111762914236029	65.995174788106
a924	loss_cnaOV41	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	0.303242401904674	-1.31176277813411	1.61500518003879	1.72678698376005	1.91973242661012	0.852181760655906	0.935266014411423	0.841265771027568	0.0651993734204006	NA	NA	0.419310073385264	0.108232934807126	65.995174788106
a925	PIK3CA_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	4.03620827523217	3.26009161684167	0.776116658390503	1.35232217559965	0.962424889519709	0.727340915777637	0.573914021668952	0.806417900079265	0.0652694568249381	NA	NA	0.750484519815987	0.285977141589145	65.995174788106
a926	loss_cnaOV40	1067	CCT007093	PPM1D	8	25	1.88706964903238	NA	4.94768824168313	4.3431807224762	0.604507519206935	0.625589480750534	0.661136326025713	0.925343978983489	0.966300645723284	0.914346248134343	0.0652898095972274	NA	NA	0.0673451503406035	0.0363103687982344	65.995174788106
a927	loss_cnaOV102	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.77255634920634	2.70039722256477	1.07215912664156	1.01094423656634	0.909518088940468	1.16996781383557	1.06055219255528	1.17882111381706	0.0652984796294549	NA	NA	0.964410590969317	0.200872998774898	65.995174788106
a928	gain_cnaOV4_(KRAS)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	6	13	2.77258872223978	NA	5.77954083069592	4.6866194174517	1.09292141324422	0.712596155373019	1.1939425415953	1.01668849878495	1.53371780777026	0.915388618102093	0.0653700675053492	NA	NA	0.780837160852852	0.025073291063105	65.995174788106
a929	loss_cnaOV40	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	7	25	1.63315443905142	NA	2.29808642353648	3.02215798222785	-0.724071558691368	0.493697045667235	0.799741085461851	0.967222134875876	1.46663133807653	0.905382469219042	0.0653957610098604	NA	NA	0.0142276327528261	0.00953117568479167	65.995174788106
a930	loss_cnaOV40	329	QL-XI-92	DDR1	7	25	2.32630161961136	NA	5.2214522540682	4.34109663457643	0.880355619491765	0.803368993426783	0.988314838963322	0.922613399437641	1.09582972045833	0.890764344300649	0.0655307378325117	NA	NA	0.168931426236868	0.0323112557227272	65.995174788106
a931	PIK3CA_mut	219	AT-7519	CDK9	6	26	2.32630161961136	NA	0.192593096502283	1.79888800057455	-1.60629490407227	1.16685307225348	1.66418328101678	1.00890318004223	1.37660425486999	0.96521514330492	0.065567394567547	NA	NA	0.290906183000066	0.0188292420620841	65.995174788106
a932	loss_cnaOV81_(RB1)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	2.42325567708305	1.17940028503581	1.24385539204724	1.75881881753699	1.22851041866121	0.961625987269061	0.707210645943112	1.01249071489581	0.065571033835107	NA	NA	0.559751703732123	0.254268900929872	65.995174788106
a933	loss_cnaOV83	1010	Gefitinib	EGFR	5	25	-0.693147180559945	NA	1.8741621440845	0.73567877738759	1.13848336669691	0.504260546837265	1.28312338478679	0.946265162302908	2.25772841805194	0.887275051016298	0.0655762298667441	NA	NA	0.954975671065705	0.00408598120062153	65.995174788106
a934	loss_cnaOV58	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	4.33022161382338	2.56895452520681	1.76126708861657	1.13730530194817	1.82349905598515	1.00779546923054	1.54863173995546	0.965872223972739	0.0656877206035519	NA	NA	0.32109426432028	0.0203830855635175	65.995174788106
a935	SMAD4_mut	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.66798685934416	4.85375145951265	0.814235399831508	0.768604554508888	0.785711801453323	1.03843493451697	1.05936842951936	1.03630287635419	0.0657920179461089	NA	NA	0.419096418569525	0.197734226610135	65.995174788106
a936	loss_cnaOV35	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.59699280625698	3.65357940712957	0.943413399127409	0.996801733343968	0.974658366327614	0.964990792271176	0.946440367797658	0.967942647106255	0.0658513398986258	NA	NA	0.702549974738703	0.103199184778328	65.995174788106
a937	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	304	SB52334	ALK5	7	25	2.99573227355399	NA	5.0215370908687	4.18326942430801	0.838267666560689	0.999511905077928	1.01215571113292	0.830264237171606	0.838677020555681	0.82820030291822	0.0660320185448516	NA	NA	0.326669298519143	0.0797530349778539	65.995174788106
a938	loss_cnaOV58	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.59171072964102	4.59562085182602	0.996089877815008	0.435103271326257	1.2579341113643	0.844796805063031	2.2893182916754	0.791845827866689	0.0660901620951305	NA	NA	0.3995603227137	0.00498236962535892	65.995174788106
a939	gain_cnaOV19	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	3.03342120524457	0.454362294612195	2.57905891063237	1.22713175327852	2.24987138824844	1.17413856874877	2.10169682574175	1.14631392892205	0.0661113695006572	NA	NA	0.942902818103015	0.0404063149235646	65.995174788106
a940	SMAD4_mut	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	4.31957186466198	3.13204818089127	1.18752368377071	0.74068195059286	0.896067110253651	1.35066665701031	1.60328422046762	1.32526199230162	0.0661440948021366	NA	NA	0.150833399038345	0.085163721260681	65.995174788106
a941	loss_cnaOV38	1010	Gefitinib	EGFR	8	22	-0.693147180559945	NA	1.61947088993022	0.673046047075932	0.946424842854287	0.77632970296249	1.31760507914393	0.785223041077	1.21910167708734	0.718291738423774	0.0662862190805552	NA	NA	0.954990721540077	0.0249945650512397	65.995174788106
a942	loss_cnaOV34	305	TPCA-1	IKK	5	27	2.99573227355399	NA	2.40473174868989	3.49565117120119	-1.0909194225113	1.0561506333412	1.18802572222357	0.931374460849668	1.03292029382221	0.918262460234854	0.0663598754031661	NA	NA	0.993265363095231	0.0825255901674001	65.995174788106
a943	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	5.27032496168384	4.29994411569221	0.970380845991626	1.01696125843409	0.907926098276272	1.0510961414753	0.954196473015905	1.06878836045569	0.06637663135918	NA	NA	0.0238021361835071	0.100301168468552	65.995174788106
a944	loss_cnaOV85	1377	Afatinib (rescreen)	ERBB2, EGFR	7	26	2.30258509299405	NA	3.61925944082378	2.39553119528559	1.22372824553818	1.19448132973986	1.72696079363179	0.747328626244752	1.0244850338554	0.708602216130623	0.0663824791061439	NA	NA	0.622716523415447	0.0483792442412658	65.995174788106
a945	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	6.36233625932375	4.46036734542806	1.90196891389569	1.55419054880301	1.39228883883571	1.34671759350979	1.22376816366598	1.3660735192607	0.0663879543334541	NA	NA	0.0905221947316004	0.155006709403321	65.995174788106
a946	loss_cnaOV43_(NF1)	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.15426455904827	0.544584635880589	0.609679923167682	0.595831469453507	0.576151827300175	1.05332535035409	1.02324223278585	1.05819316068929	0.0663974509512133	NA	NA	0.010832265497309	0.0834882977493837	65.995174788106
a947	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.48098472782748	3.72716031820748	0.753824409619993	0.921755844383115	0.810715844964391	0.912749732931688	0.817813539467699	0.929825677273032	0.0665231446152133	NA	NA	0.919775365388665	0.145277969210406	65.995174788106
a948	PTEN_mut	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	3.99335264585585	5.0468826835471	-1.05353003769125	0.942307138554796	0.766844914843128	1.33898435219282	1.11803253375225	1.37385019747672	0.0666623213556309	NA	NA	0.133217613896463	0.107127287335027	65.995174788106
a949	loss_cnaOV70	306	TG101348	JAK2	3	29	2.32630161961136	NA	4.26860196824316	2.67462309927837	1.59397886896479	0.790749605221137	1.35423853886713	1.20377160862282	2.01578206102174	1.1770296171738	0.0666812785075385	NA	NA	0.609049869329128	0.0471788319648011	65.995174788106
a950	PTEN_mut	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-3.93010304301571	-1.74776608320597	-2.18233695980974	2.23313370136067	1.24471841957506	1.58118199787525	0.977253157068035	1.75327762929288	0.0667149816072486	NA	NA	0.0289879084021003	0.144032197267263	65.995174788106
a951	loss_cnaOV16, loss_cnaOV17	1031	Elesclomol	HSP70	6	25	-1.6094379124341	NA	-3.07602461773025	-4.29587252417751	1.21984790644725	1.9492199406935	1.32844922457479	0.838668836034943	0.625813373329873	0.918249552848134	0.0667434698178776	NA	NA	0.856554458474792	0.19491316255824	65.995174788106
a952	loss_cnaOV58	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	2.89594658786878	3.83695898891635	-0.941012401047576	0.935119460868073	0.785607112501112	1.15080463538135	1.00630180466358	1.19781553154694	0.0667859005045773	NA	NA	0.0428432163728974	0.0883917029306062	65.995174788106
a953	loss_cnaOV87, loss_cnaOV88	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.2480931623944	4.41389148360623	0.834201678788175	0.797032833896244	0.650630392264763	1.26192500814107	1.04663401971815	1.28214373122722	0.0667995500069966	NA	NA	0.0675105533609268	0.205892406486355	65.995174788106
a954	TP53_mut	1091	BMS-536924	IGF1R	22	10	1.38629436111989	NA	2.60282797349755	1.9330852343502	0.669742739147347	0.906017788953009	0.867569976037917	0.748602844080851	0.739215882197301	0.771975469005944	0.0669466190865605	NA	NA	0.72111457834235	0.0610964260312567	65.995174788106
a955	RB1_mut	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	-0.337011416063682	1.06569682975197	-1.40270824581566	1.56549983283219	1.17206880972834	1.16461393229024	0.896013028170037	1.19677977450895	0.0669985152361371	NA	NA	0.955005643953358	0.257308437645224	65.995174788106
a956	loss_cnaOV56	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.73039794521013	3.70674765174356	2.02365029346657	1.51212036546542	1.62249007181376	1.25294073323637	1.33828651454192	1.24724972350947	0.0670006159023652	NA	NA	0.126765841978145	0.133470608649325	65.995174788106
a957	loss_cnaOV56	1248	FK866	NAMPT	3	29	0	NA	1.28472586638798	-2.01798708878473	3.30271295517271	2.42828230236824	2.60827007035913	1.27190859003751	1.36010255148327	1.26624654122492	0.0671207945398804	NA	NA	0.0349469156496246	0.129886989244278	65.995174788106
a958	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	152	CP466722	ATM	3	29	2.77258872223978	NA	3.49124270435214	2.55957261404713	0.93167009030501	0.0640036320426054	0.798071269187314	1.20809852099544	14.5565190688682	1.16740211842702	0.0672185025421305	NA	NA	0.534999345305055	1.05951709601134e-06	65.995174788106
a959	PIK3CA_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	6	26	0.246860077931526	2.32630161961136	0.211004084352315	1.18721782453671	-0.97621374018439	1.422791395664	1.52882129595829	0.645786578219299	0.686125698510291	0.638540124189258	0.0673243506998014	NA	NA	0.780068096237916	0.174111847027769	65.995174788106
a960	SMAD4_mut	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.9450924595332	4.31915929873464	0.625933160798563	0.600981770496439	0.762668343094931	0.837295300676633	1.04151771572291	0.820714752966548	0.0674223196257645	NA	NA	0.0334176622568397	0.125575071407051	65.995174788106
a961	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	5.00255857907651	4.04785929447061	0.954699284605904	1.02310423640813	0.896323923177188	1.04424962569905	0.933139802018242	1.06512752802781	0.0674601228884649	NA	NA	0.0380025739463304	0.106103719958351	65.995174788106
a962	loss_cnaOV35	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.03476774421158	2.59897719404473	-0.564209449833152	0.560767422248488	0.603861219818314	0.943029256747332	1.00613806624298	0.934336286743018	0.0675201734103256	NA	NA	0.85058210620557	0.0884098713688723	65.995174788106
a963	TP53_mut	294	MPS-1-IN-1	MPS1	21	10	2.99573227355399	NA	4.10727406338126	4.65465716728851	-0.547383103907251	0.717854481472494	0.90985967355288	0.699530699484027	0.762526553828061	0.60161266601672	0.0676120532938662	NA	NA	0.291192972424194	0.116107400735904	65.995174788106
a964	gain_cnaOV49	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	0.777122736853656	2.43486019904945	-1.65773746219579	2.08049010399591	1.7107097261357	0.954399037824118	0.796801416652664	0.96903491975838	0.0676858887759395	NA	NA	0.0940157648618062	0.299388143765396	65.995174788106
a965	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1495	AZD-2281	PARP1, PARP2	8	25	2.30258509299405	NA	4.07800719266215	3.39586968140212	0.682137511260025	1.139646767484	0.77968850776754	0.780455498998734	0.598551701038016	0.874884655172321	0.067722029264797	NA	NA	0.124063570024165	0.148117894070717	65.995174788106
a966	gain_cnaOV96	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	5.03603760435363	4.19048074930817	0.84555685504546	0.459259440744169	0.779891853406259	1.12279761985066	1.84113113423504	1.08419757348715	0.0678003184065384	NA	NA	0.201061602716106	0.0216710644602196	65.995174788106
a967	gain_cnaOV95_(MECOM)	1046	681640	WEE1, CHEK1	4	7	0.693147180559945	NA	3.5782272530563	1.62242472562179	1.95580252743451	0.929450709070554	1.58683145696885	1.39463828731732	2.104256318649	1.23252064284789	0.0678905722327933	NA	NA	0.574135836597581	0.0299911313730681	65.995174788106
a968	gain_cnaOV72_(ASXL1)	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.92145866070006	4.20745540762722	0.714003253072834	0.28978426518745	0.806455154410164	0.928156110812565	2.4639131203724	0.885360145779031	0.0681442435486902	NA	NA	0.201127758888988	0.00563909630175998	65.995174788106
a969	NF1_mut	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	4.98284217668462	3.76237832385562	1.22046385282901	0.764614206377211	1.19378318613453	1.05504016859201	1.59618254885904	1.0223496753886	0.0682144477636064	NA	NA	0.683010709434319	0.0372462439645875	65.995174788106
a970	NF1_mut	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	3.05787522667104	1.77955406045527	1.27832116621576	0.92745123710211	1.31400162577381	0.998214266838306	1.3783163093404	0.972845954785608	0.068270588008743	NA	NA	0.830599421551369	0.0601583321843763	65.995174788106
a971	BRCA1_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	5.62565660325309	3.86790024009173	1.75775636316136	1.34723628715218	1.41885981579522	1.24293532172854	1.30471275152256	1.23885132526373	0.0683382273790492	NA	NA	0.305049537151059	0.140403772209607	65.995174788106
a972	loss_cnaOV39	261	TL-1-85	MAP3K7 (TAK1)	9	23	2.32630161961136	NA	3.0510431860003	3.75303343442865	-0.701990248428351	1.09251894962206	0.83562617726134	0.770368192718082	0.642542858108953	0.840076899851362	0.0683706977673806	NA	NA	0.714650730089402	0.107933482847571	65.995174788106
a973	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.98071197701756	2.47052103426732	1.51019094275024	1.60093052042983	1.15787285967751	1.23949865185452	0.943320727213553	1.30428045715732	0.0684817216318924	NA	NA	0.935249766998317	0.238242383327736	65.995174788106
a974	KRAS_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	1.6094379124341	NA	0.581708988844425	1.56103614509951	-0.979327156255081	0.918840610522801	1.37757608478035	0.755621020422243	1.06582920371561	0.71090603784054	0.0685601455424137	NA	NA	0.560271807490257	0.0448481130960578	65.995174788106
a975	TP53_mut	1529	MLN4924	NEDD8-activating enzyme	12	5	0	NA	1.72332031003413	0.402224268256551	1.32109604177757	1.38152723647306	1.23959843811673	0.982121957029723	0.956257688520307	1.06574516484924	0.0685853473605884	NA	NA	0.84017500768219	0.0873915238393075	65.995174788106
a976	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	328	SNX-2112	HSP90	7	25	0.940007258491471	NA	2.10645459375048	0.301263520129361	1.80519107362111	1.56408631067535	2.33032629251014	0.821083618463595	1.15415054866228	0.774651635448284	0.0686231604338506	NA	NA	0.9429641214712	0.030565000681103	65.995174788106
a977	loss_cnaOV52, loss_cnaOV53	1030	KU-55933	ATM	9	24	2.30258509299405	NA	4.71376293466589	3.93995667355501	0.77380626111088	0.859266159466464	1.01273092735326	0.793288400046287	0.90054315835195	0.764078829046133	0.0686324605804779	NA	NA	0.508926363180242	0.042781365835371	65.995174788106
a978	loss_cnaOV52, loss_cnaOV53	1054	PD-0332991	CDK4, CDK6	9	24	1.38629436111989	0.693147180559945	3.35766883946412	1.88158977611947	1.47607906334465	1.73920089098701	1.64925711887505	0.882330885198571	0.848711078170484	0.894996326801654	0.0686373738062779	NA	NA	0.0941378054884034	0.0452619281245402	65.995174788106
a979	gain_cnaOV18_(CCNE1)	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	1.33459667925918	0.135817508127699	1.19877917113148	1.4616431048077	1.02467625063029	1.11539647237681	0.820158605878822	1.16991017445178	0.0687623200190352	NA	NA	0.127883130966591	0.199485621788759	65.995174788106
a980	gain_cnaOV19	1026	17-AAG	HSP90	3	30	0	NA	1.94515512917104	-0.778430887036158	2.7235860162072	1.43172495492811	2.21195527802744	1.25505111251219	1.90231092000764	1.23130247851847	0.0688774725877695	NA	NA	0.0498261360886621	0.0581477707456165	65.995174788106
a981	loss_cnaOV83	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.47373586473961	5.85320218467678	0.620533680062824	0.697173793407496	0.665937815433	0.926100432862089	0.890070289403612	0.931819256516236	0.0689301396759065	NA	NA	0.90404712171467	0.12004191906082	65.995174788106
a982	loss_cnaOV43_(NF1)	1028	VX-702	p38	5	26	0.693147180559945	NA	4.05002324195513	3.1879203715728	0.862102870382334	0.610035212001293	0.909267518381001	0.986268560159933	1.41320181757067	0.948128964198957	0.0690747912815052	NA	NA	0.495537344992141	0.0297472330660262	65.995174788106
a983	loss_cnaOV43_(NF1)	1022	AZD7762	CHEK1, CHEK2	5	26	0.693147180559945	NA	-0.143311767947335	-0.944689561697584	0.801377793750249	1.12259521152979	0.67689214229233	1.06256171008285	0.713861760249443	1.18390766221091	0.0691129200277305	NA	NA	0.0644713550780597	0.188756268801409	65.995174788106
a984	loss_cnaOV20	326	GSK690693	AKT	5	27	2.32630161961136	NA	5.34386327686445	3.93120297683952	1.41266030002493	0.356020525425425	1.46627720428753	1.03023185898365	3.96791813712672	0.96343330980948	0.0691663290392792	NA	NA	0.0782163085842078	0.000167035004427418	65.995174788106
a985	loss_cnaOV83	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	5.35239278406679	4.12137234188739	1.2310204421794	0.756153937773798	1.29598650441423	0.993069286851703	1.62800242210423	0.94987134355678	0.0692647523649009	NA	NA	0.347506577819455	0.0163960312090074	65.995174788106
a986	KRAS_mut	1003	Camptothecin	TOP1	7	24	-2.30258509299405	NA	-4.82262305840783	-3.36116015314337	-1.46146290526446	1.42370185525571	1.67366096482639	0.899304948058062	1.02652314448377	0.873213234925424	0.0693198537873796	NA	NA	0.220874735072603	0.0419144317345949	65.995174788106
a987	gain_cnaOV72_(ASXL1)	1026	17-AAG	HSP90	5	28	0	NA	0.99355194557417	-0.80304360540866	1.79659555098283	2.20871766897578	2.21954917593228	0.809950579770111	0.813411137248675	0.809441651694068	0.069480053774697	NA	NA	0.0498781225188136	0.149167030770435	65.995174788106
a988	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.54649790488647	2.7279672508705	0.818530654015969	1.20546083906074	1.00832743665328	0.789493220370854	0.679018867716802	0.811770685059152	0.0695384646054863	NA	NA	0.282458645981712	0.211491904195097	65.995174788106
a989	loss_cnaOV33_(ZFHX3)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.71289522767311	1.21585900250948	1.49703622516364	2.17225962408734	1.26345778046682	1.08058109612382	0.689160820632851	1.18487237825273	0.0695664672664091	NA	NA	0.452884247525296	0.263420248999846	65.995174788106
a990	gain_cnaOV48_(SOX17)	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	1.44900546130327	3.17130509547398	-1.72229963417071	1.34691510186913	1.56537836249621	1.10989270328845	1.27869947540172	1.1002449474415	0.0696004256209727	NA	NA	0.646939306101188	0.143765714224816	65.995174788106
a991	loss_cnaOV59	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.94945362354844	4.38085986913701	0.56859375441143	0.520186888613664	0.52704087767206	1.08023842985115	1.09305668185289	1.07884184794718	0.0696131169261636	NA	NA	0.340483851400673	0.111906327303512	65.995174788106
a992	loss_cnaOV16, loss_cnaOV17	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	0.704896461719555	-0.808304938647852	1.51320140036741	2.04941968382775	1.7608566171434	0.841971749570276	0.738356039179425	0.859355262453021	0.0696524954433802	NA	NA	0.0277522138650441	0.328942007502106	65.995174788106
a993	TP53_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	22	10	2.30258509299405	NA	4.38292403165124	3.78806651497618	0.594857516675058	1.05933325644543	0.569773890597552	0.633069518688573	0.561539546743855	1.04402382504962	0.0696712324182112	NA	NA	0.0381688386622831	0.0486107441514027	65.995174788106
a994	loss_cnaOV16, loss_cnaOV17	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.97541502782033	2.93346318555384	1.04195184226649	0.911196603826678	0.879239922748674	1.17993382455717	1.1434983821172	1.18505974911734	0.0696783633176492	NA	NA	0.64071223717774	0.173450218825889	65.995174788106
a995	loss_cnaOV85	1036	PLX4720	BRAF	7	26	2.30258509299405	NA	5.16720998840515	4.07653536824403	1.09067462016112	0.97627971738962	1.29283228419816	0.881070045856795	1.117174310532	0.843631949396728	0.0696904376416065	NA	NA	0.3475875525507	0.0308746835006833	65.995174788106
a996	loss_cnaOV43_(NF1)	1017	Olaparib	PARP1, PARP2	5	26	1.6094379124341	NA	4.93894686536104	3.78323077270537	1.15571609265568	0.639559226821512	1.14815303712613	1.0581786700741	1.80705092536835	1.00658714934768	0.0700623868508866	NA	NA	0.0682229443281242	0.0100426059395687	65.995174788106
a997	loss_cnaOV41	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	2.24123719617834	0.976201861919438	1.2650353342589	1.56046408182738	1.40998234800207	0.884461183913574	0.810678918528829	0.897199412497212	0.0702565995998885	NA	NA	0.803809424685079	0.148507441610099	65.995174788106
a998	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1010	Gefitinib	EGFR	8	22	-0.693147180559945	NA	1.62515011784014	0.670980873290505	0.954169244549636	0.708938917499703	1.32865934422821	0.792489986781134	1.34591178590508	0.718144382677632	0.0703320581028354	NA	NA	0.955073235725248	0.0188438441494916	65.995174788106
a999	loss_cnaOV35	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.85877806134188	1.46598419240752	1.39279386893436	0.957918523487187	1.45864370467644	0.993256815445187	1.45397947193261	0.954855434859826	0.0704191155678003	NA	NA	0.3021625924149	0.0264350958537357	65.995174788106
a1000	loss_cnaOV36	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	3.23071630608236	1.52356257184363	1.70715373423873	0.35873358096102	1.4515031937045	1.21476118611069	4.75883448007681	1.17612812816606	0.0704808051409071	NA	NA	0.302174547915905	0.000294759517517977	65.995174788106
a1001	loss_cnaOV84	1047	Nutlin-3a	MDM2	6	27	2.07944154167984	1.38629436111989	4.90297347487375	3.49097319071738	1.41200028415637	0.742410752194722	1.57107017315119	0.96095500577948	1.90191249248775	0.898750614890888	0.0704810059194428	NA	NA	0.14549840116525	0.0043234687542079	65.995174788106
a1002	gain_cnaOV94	258	STF-62247	stimulates autophagy	6	25	2.32630161961136	NA	4.9936171357528	4.36849873561122	0.625118400141583	0.50589836498711	0.656012095066962	0.988053616447945	1.23566005230618	0.952906821142945	0.0705326274798875	NA	NA	0.0424454804286173	0.0296591470271553	65.995174788106
a1003	gain_cnaOV18_(CCNE1)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.61069803398084	2.68575150305651	0.924946530924327	0.533663264920205	0.950692668920011	1.00685795465006	1.73320254873197	0.972918547878431	0.0705349797220051	NA	NA	0.964486963716604	0.0272645275113484	65.995174788106
a1004	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1061	SB590885	BRAF	3	30	1.6094379124341	NA	5.13925378553952	3.80636842812788	1.33288535741164	0.663559391301807	1.26187642899917	1.08182182966266	2.00869036725818	1.05627248974671	0.0705529053253011	NA	NA	0.554032115622745	0.0452800340665552	65.995174788106
a1005	loss_cnaOV42	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.6223386269853	4.84322503827757	0.779113588707731	0.679768084086029	0.792969774947637	0.995378962751411	1.14614617388999	0.982526211366857	0.070638548337531	NA	NA	0.943255046341223	0.0997074052640881	65.995174788106
a1006	loss_cnaOV56	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	3.13939729924996	2.20340566146332	0.935991637786644	0.777148334230442	0.867991566086716	1.0857944440282	1.20439251628004	1.07834185763636	0.0707234836475935	NA	NA	0.574676871346489	0.160258239542317	65.995174788106
a1007	loss_cnaOV39	274	PXD101, Belinostat	HDAC	9	21	2.99573227355399	NA	-0.27309525334687	1.33812906480017	-1.61122431814704	0.869179789947635	2.24081946535749	0.82627188607379	1.85372961587626	0.719033524590519	0.0708774462032894	NA	NA	0.390572063278187	0.00843158759323863	65.995174788106
a1008	gain_cnaOV18_(CCNE1)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-0.809014674658899	-2.50366699521035	1.69465232055145	1.77345570420687	1.49651326254516	1.11087371299905	0.955565067980842	1.13240046912068	0.0709235216028312	NA	NA	0.107175501219622	0.149865485579092	65.995174788106
a1009	TP53_mut	291	KIN001-266	MAP3K8 (COT)	22	10	2.99573227355399	NA	3.0627922649349	3.82966883233876	-0.766876567403855	1.05684968803109	1.04738495398419	0.727573628031881	0.725625011852487	0.732182149921769	0.0709261673460668	NA	NA	0.948369349655409	0.0719369759017899	65.995174788106
a1010	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1268	XAV 939	TNKS1 (tankyrase-1)	8	24	1.6094379124341	NA	3.42357799997944	2.66662422075418	0.756953779225255	1.17530928608652	0.977275851023806	0.737121371968777	0.644046454993746	0.774554879701837	0.0709682885335074	NA	NA	0.28273493009184	0.130320225641101	65.995174788106
a1011	gain_cnaOV49	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.2078873377721	4.0020592745182	-0.794171936746104	1.35945807149386	0.621742251498704	1.14154077846257	0.584182736782324	1.2773330666072	0.0709991147811199	NA	NA	0.953486099275761	0.418442057060399	65.995174788106
a1012	PIK3R1_mut	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	2.37006248354602	3.45620414854669	-1.08614166500067	0.529248493204592	0.999929585462264	1.15376474537861	2.05223383523323	1.08621815054962	0.0710502567117653	NA	NA	0.532797665063717	0.0143959491801501	65.995174788106
a1013	loss_cnaOV36	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	5.02947210198014	4.39218877669274	0.637283325287402	0.734513328361376	0.509200698724391	1.20874850000847	0.867626632057331	1.25153662766739	0.0710648982332377	NA	NA	0.340766108862424	0.269088267722577	65.995174788106
a1014	PIK3CA_mut	344	THZ-2-49	CDK9	6	26	2.99573227355399	NA	0.882562377094628	2.98062112589963	-2.098058748805	1.43237137377374	2.3192307254063	0.955212869339132	1.46474495875845	0.90463563017752	0.0710897990613745	NA	NA	0.362042105987376	0.0151165773070703	65.995174788106
a1015	loss_cnaOV58	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	3.64895796036388	1.74430016726063	1.90465779310325	3.02640728367462	1.6238181057044	1.01714813067559	0.629346156869753	1.17295021308869	0.0711360618544873	NA	NA	0.11418635870656	0.23560333573443	65.995174788106
a1016	gain_cnaOV18_(CCNE1)	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	3.12934810054349	1.25145905615771	1.87788904438577	2.82850764062636	1.59830368617839	1.09704591481521	0.6639151393524	1.17492630507278	0.0711687865355349	NA	NA	0.595750840172953	0.368958595674328	65.995174788106
a1017	TP53_mut	1052	RO-3306	CDK1	23	10	1.6094379124341	NA	3.66655064688022	3.05683819108079	0.60971245579943	0.903177851801844	0.765506326623877	0.70448897843878	0.675074631849144	0.796482582303994	0.071206593994873	NA	NA	0.784137075797733	0.0605615710608028	65.995174788106
a1018	loss_cnaOV52, loss_cnaOV53	1199	Tamoxifen	ER	8	24	1.6094379124341	NA	4.42429125632466	3.83169665884209	0.592594597482571	0.414064823403858	0.790680033617212	0.822330021671592	1.43116382746811	0.749474594383726	0.0712623049656509	NA	NA	0.504422934436575	0.0120338644314619	65.995174788106
a1019	BRCA1_mut	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	3.21658218546709	2.19513585222577	1.02144633324132	0.135924196289219	0.883171203126153	1.19758708860489	7.51482341722217	1.15656661995513	0.0712794945938054	NA	NA	0.574765619447058	1.03314679377694e-05	65.995174788106
a1020	loss_cnaOV58	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	3.25687967662194	2.10862356086047	1.14825611576146	1.52281281541943	1.32549523800213	0.84778339223923	0.754036283471385	0.866284602796603	0.0712869728816033	NA	NA	0.508128724888031	0.173438427627553	65.995174788106
a1021	loss_cnaOV84	1010	Gefitinib	EGFR	6	24	-0.693147180559945	NA	1.75467514706451	0.718113719696884	1.03656142736762	0.537667010349737	1.30764667716764	0.858978234352374	1.92788734925985	0.792692281077645	0.071413759550833	NA	NA	0.955094413205703	0.00687348698338189	65.995174788106
a1022	loss_cnaOV16, loss_cnaOV17	1066	AZD6482	PI3Kbeta	6	27	1.6094379124341	NA	3.35504034193091	2.1622410468103	1.19279929512061	1.58452568877867	1.14831590023233	0.9703963970393	0.752780029738741	1.03873794212836	0.0714394190463784	NA	NA	0.0940184680389225	0.129869665755324	65.995174788106
a1023	NF1_mut	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	5.27204109609372	4.42819347351833	0.843847622575387	0.462204083698183	1.02596024737752	0.85737294333104	1.82570352001999	0.822495437549716	0.0715392475141075	NA	NA	0.169975343733373	0.0225920121276897	65.995174788106
a1024	loss_cnaOV87, loss_cnaOV88	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	4.6787285208653	3.2786608478748	1.4000676729905	0.737455476680005	1.1813406633406	1.21002336856573	1.89851145901519	1.18515151169975	0.0715766365441392	NA	NA	0.302698083546992	0.0569660347524574	65.995174788106
a1025	gain_cnaOV19	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	3.22607220988095	1.58896007937497	1.63711213050598	1.1056497603005	1.67535340647266	0.995468362157689	1.48067877305109	0.977174203473163	0.0715789057420734	NA	NA	0.207338650505346	0.103388781898171	65.995174788106
a1026	loss_cnaOV20	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	3.75819746418941	2.42917884150481	1.3290186226846	1.37697967730607	1.18718548916163	1.08684641443099	0.965169380919763	1.11947007002513	0.0716323037999386	NA	NA	0.935403165030258	0.148031879600103	65.995174788106
a1027	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.8243073950949	4.81308288763966	1.01122450745524	0.674251311215403	0.819663814209029	1.24769612270626	1.49977388346848	1.2337064171011	0.0716450964483465	NA	NA	0.134020645223708	0.105016649406633	65.995174788106
a1028	loss_cnaOV87, loss_cnaOV88	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.76299775406357	3.8988295379523	0.864168216111272	0.90133462383035	0.707890386518392	1.19624607797289	0.958765139231937	1.22076557694405	0.0716997599931335	NA	NA	0.504497320230387	0.234220368462619	65.995174788106
a1029	gain_cnaOV26	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-1.73692382312463	-0.192130935724916	-1.54479288739971	2.26993522577208	1.25370203355424	1.15052914853421	0.680544920339866	1.23218503763628	0.0717802942119515	NA	NA	0.883460352652189	0.359437708857449	65.995174788106
a1030	loss_cnaOV56	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	5.02527586330318	3.78874613936673	1.23652972393645	0.768097073082051	1.03455151169017	1.21292063003738	1.60986126268491	1.19523262975693	0.0718810651894139	NA	NA	0.293251664362164	0.0892361807177966	65.995174788106
a1031	loss_cnaOV40	266	Zibotentan, ZD4054	Endothelin A Receptor	7	25	2.99573227355399	NA	5.46424636422065	5.7853049908666	-0.32105862664595	0.555905272947794	0.435378615931559	0.694922706228061	0.577541970313531	0.737423968237384	0.0719726116039765	NA	NA	0.357923596261588	0.194961349488275	65.995174788106
a1032	gain_cnaOV51_(MYC)	1114	Cetuximab	EGFR	8	24	4.18661983833127	NA	5.07899001531118	6.07018275306424	-0.991192737753062	1.46890289232747	1.13222206097936	0.813035515888914	0.674784386994105	0.875440226712851	0.0719949399187086	NA	NA	0.551329349552689	0.11203053770759	65.995174788106
a1033	loss_cnaOV41	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.62411182717232	5.05324047896873	0.570871348203589	0.618740777414531	0.540434767543198	1.03509045014423	0.922634112768566	1.05631869466643	0.0719997119829454	NA	NA	0.00850566489580206	0.109167409528938	65.995174788106
a1034	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1262	UNC1215	LMBL3	3	30	0	NA	3.30681706515542	2.72777226847794	0.579044796677484	0.682168071835089	0.449820303158749	1.23647660442315	0.848830105929474	1.28728025971991	0.0720007352461308	NA	NA	0.0937839204389053	0.27708535967845	65.995174788106
a1035	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	0.692902341181596	-0.806056041046985	1.49895838222858	2.06204890081819	1.76094247032268	0.833224748314094	0.72692669006725	0.851225072647552	0.07206436778145	NA	NA	0.0279939343950788	0.335058017915252	65.995174788106
a1036	KRAS_mut	298	OSI-930	KIT, VEGFR, PDGFR	7	25	2.32630161961136	NA	3.74130720580128	4.65043861966	-0.909131413858719	1.20935371347847	0.82276732727394	0.995467165013497	0.751749801341233	1.10496781255392	0.0720756698368516	NA	NA	0.0241081769688685	0.100020719806599	65.995174788106
a1037	loss_cnaOV52, loss_cnaOV53	269	NSC-207895	MDM4	8	23	2.99573227355399	NA	4.77736278315119	3.57457170961222	1.20279107353897	1.69654775547696	1.44427988238091	0.797058045006467	0.70896387658762	0.832796390929546	0.0721278294646196	NA	NA	0.701111240877484	0.101259905080135	65.995174788106
a1038	gain_cnaOV18_(CCNE1)	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.70111632941911	3.70988496772116	1.99123136169794	1.62442591978334	1.61846958371888	1.23000472345611	1.22580619863756	1.23031744416385	0.0722971844457391	NA	NA	0.127593780941523	0.15725142330999	66.0864019455626
a1039	gain_cnaOV96	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	1.23495122553857	2.51378815110805	-1.27883692556949	2.73977932011355	1.01313301601206	0.930110660240741	0.466766398366889	1.26225964938277	0.0724451135272174	NA	NA	0.811893362531622	0.358256023889433	66.157887067242
a1040	PIK3R1_mut	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.96140387983021	4.15355029249002	0.807853587340195	0.878954286309908	0.747250303326388	1.05359034895488	0.919107625871861	1.08110171885382	0.072685209604207	NA	NA	0.292213538751771	0.11017093712462	66.1659838199263
a1041	ARID1A_mut	1043	JNK Inhibitor VIII	JNK	9	24	2.30258509299405	NA	3.89273348025093	4.64802466331841	-0.755291183067476	1.17430444193022	0.868541336381186	0.789353364098186	0.643181747508335	0.869608792846209	0.0727243291968198	NA	NA	0.352014857873605	0.105473380048332	66.1659838199263
a1042	loss_cnaOV57_(ZNRF3)	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	3.09483646343587	1.30765493973136	1.7871815237045	1.77691122946036	1.84226937348025	0.973496169786632	1.00577985780824	0.970097831202782	0.0729018788697841	NA	NA	0.771755655304505	0.134709668491247	66.1659838199263
a1043	loss_cnaOV36	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.02168012963792	2.95087979763924	-0.92919966800132	0.206175173113035	0.784838843098785	1.22248184469869	4.50684558170295	1.18393690140584	0.0729528083001276	NA	NA	0.0145050524105021	0.0004736464065304	66.1659838199263
a1044	loss_cnaOV16, loss_cnaOV17	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	1.38629436111989	0.693147180559945	3.83312989334196	2.59454063047484	1.23858926286712	1.46240084295667	1.49963798037959	0.82921175004441	0.846956064633377	0.825925509404346	0.0730199245070425	NA	NA	0.967268235338822	0.101039108490241	66.1659838199263
a1045	TP53_mut	1495	AZD-2281	PARP1, PARP2	23	10	2.30258509299405	NA	3.72873937408195	3.17597939724654	0.552759976835413	0.954339599212256	0.694039524063825	0.623406905830537	0.579206791053918	0.796438758413677	0.0730926451219517	NA	NA	0.124831456681652	0.0746474873773636	66.1659838199263
a1046	loss_cnaOV34	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.00439771243956	4.48410426649971	-0.47970655406015	0.599715656499387	0.613059448421216	0.784735523136723	0.799889995969516	0.782479668644723	0.0732087717142592	NA	NA	0.247871315988934	0.155618670488604	66.1659838199263
a1047	NF1_mut	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	1.60995113010456	0.636594862547713	0.973356267556845	0.515692552909555	1.04308796207431	0.97053459580406	1.88747396499161	0.933148787971056	0.0733270152288913	NA	NA	0.760625593382359	0.0191439497088279	66.1659838199263
a1048	loss_cnaOV36	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.69533154422045	3.71050476613531	1.98482677808514	1.54380874221478	1.62509045471212	1.22549236420735	1.2856688291826	1.22136387690293	0.0733808532977657	NA	NA	0.127755454358804	0.143828488090298	66.1659838199263
a1049	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	3.26464003242801	1.59750214109501	1.667137891333	1.24730729481403	1.59799728379552	1.06810667601095	1.33658954634878	1.04326703695845	0.073414249596695	NA	NA	0.302898103950215	0.125793894954928	66.1659838199263
a1050	gain_cnaOV4_(KRAS)	1026	17-AAG	HSP90	7	26	0	NA	0.795574029914918	-0.887941516652925	1.68351554656784	2.58720484687301	2.10168553849331	0.76383860523169	0.650708253195568	0.8010311322667	0.0734365865406183	NA	NA	0.0502087257086262	0.15011821478184	66.1659838199263
a1051	loss_cnaOV36	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.31143957850167	2.65444237893835	0.656997199563324	0.886104695197817	0.505148924223001	1.21894354433617	0.741444214350601	1.30060100706715	0.0734682102884578	NA	NA	0.11745716492699	0.326863827641999	66.1659838199263
a1052	loss_cnaOV55	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-2.89300590378159	-2.17504205601026	-0.71796384777133	0.892076290911578	0.652507209299397	1.02454893786464	0.804823371146509	1.10031557895309	0.0735795753520257	NA	NA	0.645281536702552	0.208355939624819	66.1659838199263
a1053	loss_cnaOV42	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	5.08294465042216	4.0704719730143	1.01247267740786	1.13949385342843	0.891051622942799	1.10180306085935	0.888528423704615	1.13626713799595	0.0736452844690642	NA	NA	0.0384550869635375	0.172682274053749	66.1659838199263
a1054	gain_cnaOV96	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	5.41082089661665	4.40654607710035	1.0042748195163	0.507051515678585	0.971910585548674	1.07173214621753	1.98061693627378	1.03329960023982	0.0737049628230955	NA	NA	0.302646438937179	0.0156432123371169	66.1659838199263
a1055	loss_cnaOV59	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.69444531145622	4.61729313147617	1.07715217998004	0.4266815912209	1.23863567131219	0.912205708895496	2.52448711672302	0.86962793412766	0.0738915764370862	NA	NA	0.401108626711599	0.00512415523230438	66.1659838199263
a1056	loss_cnaOV58	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.89095494806024	1.27921886762668	1.61173608043355	1.60496059129066	1.87109094762893	0.87697546683863	1.00422159221831	0.861388422874881	0.0739510611415609	NA	NA	0.771846461989642	0.089941542455562	66.1659838199263
a1057	loss_cnaOV16, loss_cnaOV17	341	EX-527	SIRT1	6	25	2.99573227355399	NA	6.18507587189352	5.67449021656892	0.510585655324601	0.440712433506275	0.546535169670519	0.963732793164355	1.15854606429508	0.934222871022938	0.0739539023361359	NA	NA	0.0938525989670469	0.0379557243420594	66.1659838199263
a1058	gain_cnaOV50	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-4.92552868107417	-3.50829964296293	-1.41722903811124	0.891471273940027	1.74070291640146	0.847136977638832	1.58976411191302	0.814170542691489	0.0739860096516315	NA	NA	0.221746999345753	0.0381821864659882	66.1659838199263
a1059	loss_cnaOV59	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	2.99711961423417	1.49596375159913	1.50115586263504	0.651045296305922	1.46583606480329	1.06785188151998	2.30576255009091	1.02409532599165	0.0740098748027758	NA	NA	0.302840480464317	0.0073118774178287	66.1659838199263
a1060	loss_cnaOV38	260	NG-25	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	2.37954154189153	3.2227951305132	-0.843253588621674	1.00489011327487	1.02917619192123	0.8238430370575	0.839150049823426	0.819348130321121	0.0741270892669674	NA	NA	0.41179708636039	0.0630964451707663	66.1659838199263
a1061	loss_cnaOV59	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.69346498234886	4.79501418925184	0.898450793097018	0.609553526506585	0.829575875917204	1.10975665241134	1.47394897089044	1.08302425272874	0.0743027031391608	NA	NA	0.134425668090819	0.0492167457279151	66.1659838199263
a1062	loss_cnaOV34	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.17535971854519	3.16691173610086	-0.991552017555671	1.27734919071252	0.981022174833574	0.96690392653618	0.77625760032194	1.0107335420057	0.0743915802203665	NA	NA	0.411844260826651	0.161290061331268	66.1659838199263
a1063	PTEN_mut	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	5.18440530476514	4.35326347481998	0.831141829945155	0.507991347967368	0.712351004027387	1.18635559611695	1.63613383037096	1.16675883833414	0.0746401256627522	NA	NA	0.503728061578079	0.0847567845077348	66.1659838199263
a1064	loss_cnaOV40	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	5.13414093158359	4.43564014617039	0.698500785413205	0.72851814568328	0.943198258363285	0.772380151637731	0.958796688252807	0.740566237500587	0.0746543455863032	NA	NA	0.940268207920712	0.0577797150811459	66.1659838199263
a1065	SMAD4_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	4.11303243097702	2.45401715307875	1.65901527789827	1.6265952257048	1.62312808127039	1.02189844944576	1.01993123530743	1.02210989819102	0.0746658728836488	NA	NA	0.623847346798323	0.130676213024924	66.1659838199263
a1066	SMAD4_mut	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.761363332844848	-0.180161334436616	0.941524667281463	1.01980359669206	0.944952101533368	0.986857950963852	0.923241171472126	0.996372901603855	0.0747058553449372	NA	NA	0.153874795269817	0.244545223139605	66.1659838199263
a1067	gain_cnaOV49	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	1.68781293473315	2.15806207658103	-0.470249141847874	0.270565055194997	0.560118692655798	0.861119126565733	1.73802615237568	0.839552666271842	0.0747135047750744	NA	NA	0.0338002536969656	0.0649836408080401	66.1659838199263
a1068	SMAD4_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	5.02297145023809	4.39286125790743	0.630110192330658	0.539409155082292	0.52718259515702	1.19337580792344	1.16814886509394	1.195240886401	0.0747170973897063	NA	NA	0.341449653739277	0.171089442969453	66.1659838199263
a1069	gain_cnaOV18_(CCNE1)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	2.12031990773014	1.09133378143478	1.02898612629536	1.47386516452223	1.16656101033926	0.857670558117012	0.698154859117602	0.882067990594089	0.0747371728923827	NA	NA	0.244773208097942	0.259927460407845	66.1659838199263
a1070	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	206	Ruxolitinib	JAK1, JAK2, TYK2	7	25	1.65632149833295	0.0237165266173161	4.7754888192558	4.36133876380957	0.414150055446229	0.471756700977676	0.546574475069892	0.777815776795359	0.877889078391336	0.757719349029737	0.0747449141843811	NA	NA	0.341454721100751	0.0733182337177376	66.1659838199263
a1071	loss_cnaOV43_(NF1)	1003	Camptothecin	TOP1	5	26	-2.30258509299405	NA	-2.31408469069974	-3.9559916011845	1.64190691048477	2.03468624407378	1.55303391940841	1.00856519141415	0.806958279325366	1.05722540246269	0.0747489135071368	NA	NA	0.221884066772081	0.148498965540574	66.1659838199263
a1072	gain_cnaOV96	263	FR-180204	ERK	5	27	2.99573227355399	NA	5.33852768682041	4.71421663439821	0.6243110524222	0.962872700532375	0.670136571715486	0.871801845881144	0.648383791623769	0.931617641496602	0.0748185542399135	NA	NA	0.753732469274622	0.226537253316233	66.1659838199263
a1073	loss_cnaOV43_(NF1)	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.46293609315016	3.73038328868557	0.732552804464592	0.896343122436238	0.817968840871093	0.884193424637636	0.817268282790559	0.895575439871845	0.0749623004605855	NA	NA	0.920040261921379	0.14598618742296	66.1659838199263
a1074	loss_cnaOV40	1268	XAV 939	TNKS1 (tankyrase-1)	8	24	1.6094379124341	NA	3.33053022713686	2.69764014503504	0.632890082101823	1.18045983036511	0.998176742257371	0.606471409976476	0.536138601095874	0.634046111583953	0.0749940442530735	NA	NA	0.283482039194338	0.201348611251301	66.1659838199263
a1075	loss_cnaOV39	276	CAY10603	HDAC6	9	22	2.99573227355399	NA	0.500491451329969	1.8147488550944	-1.31425740376443	0.908013440286083	1.91363344020269	0.774536736365514	1.44739862369256	0.686786390827923	0.075109306449088	NA	NA	0.596336780471641	0.0151398122578127	66.1659838199263
a1076	loss_cnaOV59	1030	KU-55933	ATM	4	29	2.30258509299405	NA	5.0477831737722	4.02729978904222	1.02048338472998	0.957936671069255	0.98201251551367	1.04161945458153	1.06529316138499	1.03917553860929	0.0751247019014997	NA	NA	0.509980892407722	0.118663281584401	66.1659838199263
a1077	loss_cnaOV39	1164	XMD8-92	MAP2K5 (ERK5)	7	16	2.30258509299405	NA	2.53640923441834	3.09140242591124	-0.554993191492898	0.416115777161618	0.933834802483729	0.676839524963931	1.33374705299227	0.594316243105073	0.0752172524332063	NA	NA	0.296049001086256	0.0620197347815813	66.1659838199263
a1078	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	301	PHA-793887	CDK-pan	7	25	2.32630161961136	NA	3.9693066277582	2.74118871033391	1.22811791742428	0.936630654067878	1.66823837649923	0.792437910902263	1.3112083317906	0.736176516932472	0.0753877525309286	NA	NA	0.647690521750007	0.021272850506074	66.1659838199263
a1079	loss_cnaOV20	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.84049652669352	1.8240653575974	1.01643116909613	1.08575350838511	0.892536666996713	1.1061230873521	0.93615278352442	1.13881166643417	0.0755009828079438	NA	NA	0.436869111322414	0.239945408974428	66.1659838199263
a1080	gain_cnaOV96	157	JNK-9L	JNK	4	15	1.63315443905142	NA	0.610629376523583	-0.202733923903042	0.813363300426625	0.914933728258642	0.967805623910815	0.8484136481036	0.888986027408419	0.840420101238818	0.0755666556877296	NA	NA	0.154107409898093	0.179859214306366	66.1659838199263
a1081	loss_cnaOV52, loss_cnaOV53	1022	AZD7762	CHEK1, CHEK2	8	23	0.693147180559945	NA	-0.302211792667369	-0.99394752619717	0.6917357335298	0.840269301883438	0.720040757523019	0.92129942944141	0.823230995086095	0.960689691941065	0.0755983703282978	NA	NA	0.0651438624351355	0.0623408317501557	66.1659838199263
a1082	gain_cnaOV48_(SOX17)	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	2.79800072146855	3.63755991373149	-0.839559192262934	0.301621014035511	0.917216151939857	0.942861797010416	2.78349038427439	0.915334068733217	0.0756091997187837	NA	NA	0.125171422371155	0.0103426720629199	66.1659838199263
a1083	loss_cnaOV20	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	3.08876497232976	2.21506677731506	0.873698195014705	0.706710868131723	0.965297127547288	0.944607579347787	1.2362880414227	0.905108044022335	0.0756330621104894	NA	NA	0.368413714608519	0.086951306139444	66.1659838199263
a1084	loss_cnaOV102	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	4.16849815782967	2.09572265695185	2.07277550087782	0.643520080821213	1.74667465135704	1.22123373066932	3.22099583626466	1.18669810617989	0.0757338702212439	NA	NA	0.0949969584681614	0.00587875856678832	66.1659838199263
a1085	loss_cnaOV56	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.32767639303972	1.54069469629319	0.786981696746531	0.984906371424204	0.616200168745757	1.21570247325978	0.79904214205512	1.2771526797021	0.075849318608139	NA	NA	0.18773189385266	0.298978118644927	66.1659838199263
a1086	loss_cnaOV85	1378	Bleomycin (50 uM)	DNA damage	7	25	3.91202300542815	NA	3.36038349152551	1.67272839508712	1.68765509643839	3.07644897404482	1.41618938677486	0.902427221477272	0.548572432267426	1.19168743403857	0.0760357117160602	NA	NA	0.114849477014102	0.203015391344372	66.1659838199263
a1087	loss_cnaOV39	1072	BMS-708163	g-secretase	10	23	1.6094379124341	NA	4.2264588433633	3.67394887457887	0.552509968784431	0.955120090158695	0.775107419654109	0.664558410503321	0.578471727772609	0.712817287997304	0.076055095024068	NA	NA	0.9200721472428	0.128449929331931	66.1659838199263
a1088	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	5.02062911807164	4.39310356813155	0.627525549940092	0.612777196462636	0.521726932269311	1.18785331447778	1.02406805207928	1.20278542495515	0.0760680640467584	NA	NA	0.341693442544034	0.212190508649064	66.1659838199263
a1089	TP53_mut	1026	17-AAG	HSP90	23	10	0	NA	-0.135638681360763	-1.43977715522741	1.30413847386665	2.08993626418664	2.54457514032686	0.584424729399652	0.624008729938081	0.512517179468759	0.0760807600643094	NA	NA	0.0504199260059942	0.175224597636309	66.1659838199263
a1090	BRCA1_mut	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.90059211346463	3.58868098430183	1.3119111291628	1.31791112292005	1.5289761672978	0.86890704913241	0.995447345687503	0.858032425372183	0.0761003632347989	NA	NA	0.146325535233146	0.138043624324172	66.1659838199263
a1091	gain_cnaOV18_(CCNE1)	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	5.02619306786082	3.94942635890293	1.0767667089579	0.671520849717849	1.10326738427078	1.00823104546627	1.60347472369669	0.975979825298291	0.0761925181164632	NA	NA	0.81078786965158	0.0365029746062363	66.1659838199263
a1092	loss_cnaOV52, loss_cnaOV53	261	TL-1-85	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	4.04346156636414	3.39297771395619	0.650483852407944	0.924371927908516	0.92262534792151	0.704724236687729	0.703703598917947	0.705035748121763	0.0762259013672215	NA	NA	0.715499851598714	0.110213003081859	66.1659838199263
a1093	loss_cnaOV33_(ZFHX3)	255	CP724714	ERBB2	4	28	2.32630161961136	NA	5.18138816114416	4.30559546457061	0.875792696573549	0.671882114365303	0.933112586271557	0.962019445544709	1.30349160641204	0.938571303676182	0.0762521558224291	NA	NA	0.776072542110074	0.0707794991788509	66.1659838199263
a1094	gain_cnaOV48_(SOX17)	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.1200007037083	3.36814310870826	-1.24814240499995	1.37753729085653	0.999970874473227	1.21242533181544	0.906067961487909	1.24817875886381	0.0762893684696017	NA	NA	0.0510677701431217	0.253794497404976	66.1659838199263
a1095	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-0.299498339430484	-1.81091604111504	1.51141770168455	1.7926601305627	1.09159693194867	1.26414451892856	0.843114473243813	1.38459321151301	0.0766157284298343	NA	NA	0.590049522243309	0.278674035543696	66.2891851432218
a1096	gain_cnaOV49	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-1.29837527617899	0.0158763406942979	-1.31425161687329	1.43817776316271	1.18610069039783	1.09050305359368	0.913831134464981	1.10804388490194	0.0766290412344388	NA	NA	0.755490433901819	0.250052874234257	66.2891851432218
a1097	loss_cnaOV16, loss_cnaOV17	279	BIX02189	MAP2K5 (MEK5)	6	26	2.99573227355399	NA	3.92656291416937	4.54763381534841	-0.621070901179037	0.620510439782463	0.715459279752589	0.886574474222959	1.00090322637726	0.868073024915979	0.0766410121333624	NA	NA	0.504048511853008	0.0627700028702771	66.2891851432218
a1098	gain_cnaOV48_(SOX17)	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	1.62106303806755	3.03817740270101	-1.41711436463346	1.09750083946433	1.18936559185546	1.1974300764151	1.29121939016021	1.19148760846756	0.076713823592435	NA	NA	0.209748110105097	0.142521530052729	66.2917320092496
a1099	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	2.95042196658368	0.462948422749528	2.48747354383415	1.18100044242663	2.26161708093181	1.12754056965927	2.10624268583937	1.09986503232867	0.0770128951275176	NA	NA	0.94315231072128	0.039051130252442	66.4869730610577
a1100	PTEN_mut	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	4.35597534698434	2.75525543970962	1.60071990727472	1.28334478247143	1.15290266685414	1.37749132795169	1.2473030857632	1.38842588649961	0.0770799048565417	NA	NA	0.209808459485702	0.154455750234054	66.4869730610577
a1101	gain_cnaOV94	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.88489419112897	4.41292379345546	0.471970397673513	0.605261095377491	0.560201823463932	0.828746724846053	0.779779835971703	0.842500645133836	0.0771698190799922	NA	NA	0.597697820854676	0.0965774610787879	66.5040723113152
a1102	loss_cnaOV44	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	4.09720663364331	1.82928532472161	2.2679213089217	3.79979549854858	1.66515482944553	1.20361064157694	0.596853517455869	1.36198824806993	0.0773543679793464	NA	NA	0.115020429542302	0.410084131054449	66.5519015807936
a1103	NF1_mut	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	5.06631895276191	4.34044931689383	0.725869635868076	0.471216126053499	0.722454850084733	1.03489798438936	1.54041764645734	1.00472664247869	0.0773656012227171	NA	NA	0.504162314102084	0.0421611329457256	66.5519015807936
a1104	loss_cnaOV36	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-2.80676538257995	-4.32585978543008	1.51909440285013	3.19983088696245	0.999234178758228	1.19554490238557	0.474742089977193	1.52025864921669	0.0775031531194517	NA	NA	0.196393819710714	0.497756026011315	66.5813910398713
a1105	loss_cnaOV87, loss_cnaOV88	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	4.23950132274899	2.49667077316483	1.74283054958417	1.66212432176452	1.63549276284539	1.06450342105313	1.04855607174677	1.06563024256496	0.077601441470763	NA	NA	0.624215501478689	0.203481287738925	66.5813910398713
a1106	loss_cnaOV40	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	7	25	2.32630161961136	NA	5.54417460836956	5.02995319237722	0.514221415992338	0.698698452995481	0.505177172660079	0.936033085162233	0.735970451612927	1.01790311166404	0.0777253495668692	NA	NA	0.00863465127952657	0.107220181823006	66.5813910398713
a1107	KRAS_mut	309	Y-39983	ROCK	7	25	2.99573227355399	NA	4.16795587044822	5.18726303941743	-1.01930716896921	1.27586089686638	1.14088472005975	0.871853047734034	0.798917163675687	0.893435726719023	0.0777577981844904	NA	NA	0.349774278575067	0.088824693221741	66.5813910398713
a1108	loss_cnaOV83	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.89476836722762	2.17845033009941	0.716318037128208	0.717251791002494	0.888015953196937	0.826712753467106	0.998698150515622	0.80664996450728	0.0777816493785601	NA	NA	0.575750594630055	0.0928869919527364	66.5813910398713
a1109	loss_cnaOV16, loss_cnaOV17	229	LY317615	PRKCB (PKCbeta)	6	26	2.99573227355399	2.32630161961136	1.80177229576207	2.96761410270218	-1.16584180694011	0.993301861117767	1.72640218702203	0.716419440243967	1.17370343555803	0.675301395992282	0.0779156811420819	NA	NA	0.29842566050169	0.0457269448230465	66.5813910398713
a1110	PTEN_mut	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	4.14977090149083	2.89427940561988	1.25549149587095	0.809207420049524	1.03685108928193	1.22696258726855	1.55150764163052	1.21086963099054	0.0779469840691733	NA	NA	0.412461323780202	0.0972324601638253	66.5813910398713
a1111	loss_cnaOV41	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	5.00620262129265	4.0905962207385	0.915606400554146	1.01149661049502	0.91302613867874	0.988433821309119	0.905199672499203	1.00282605477116	0.0779612594887579	NA	NA	0.189255785264081	0.114605444085249	66.5813910398713
a1112	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.751451309486001	-0.178302830056832	0.929754139542833	1.03123982472601	0.945260076736121	0.972773212379488	0.901588667592294	0.983596115423781	0.0783255111028493	NA	NA	0.154835170092688	0.253128066244093	66.6468289575284
a1113	gain_cnaOV19	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	0.959043601153943	2.45790789799389	-1.49886429683995	2.075757016695	0.995194393833803	1.26442266306817	0.722080804634075	1.50610203004244	0.0783427094094114	NA	NA	0.656892337288313	0.336724214729704	66.6468289575284
a1114	loss_cnaOV43_(NF1)	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	6.29887787082769	5.39798060024266	0.900897270585027	0.848690011885565	0.940778004964255	0.969721140084057	1.06151510913092	0.957608772559747	0.0783432580071713	NA	NA	0.28146287219983	0.0760568878702352	66.6468289575284
a1115	gain_cnaOV96	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	3.18752340274077	1.50660248861085	1.68092091412992	1.19938876876396	1.53482890195637	1.11792904888914	1.40148128605724	1.09518455900025	0.0784989904762177	NA	NA	0.0325750384884339	0.0577290680177075	66.6468289575284
a1116	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.96518581445147	0.765462957588706	1.19972285686277	0.272642809274341	1.27622497261953	0.992148571623402	4.40034659287703	0.940055932615283	0.0785042752932906	NA	NA	0.955225013780138	0.000304433608669197	66.6468289575284
a1117	loss_cnaOV34	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	2.87050605328153	3.66916278740723	-0.798656734125694	0.399008186143252	0.911521740446819	0.927594755636271	2.00160488396336	0.876179578266778	0.0785894121794039	NA	NA	0.647891740576942	0.00677732677614128	66.6468289575284
a1118	loss_cnaOV44	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	5.64453553771428	4.17422609600127	1.47030944171302	0.827789272303317	1.27033073597119	1.17952206443507	1.77618808422329	1.15742255152863	0.0785895873006403	NA	NA	0.349168344521731	0.0686327566598362	66.6468289575284
a1119	gain_cnaOV49	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-3.61404962621878	-2.16667508936931	-1.44737453684947	1.02729446435892	1.6018723191725	0.921215986085117	1.40891885147331	0.903551749740677	0.0787013825881795	NA	NA	0.108145919373118	0.114115422298435	66.6468289575284
a1120	PIK3R1_mut	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	3.41488026737352	4.37476092679549	-0.959880659421974	0.96876399128022	0.912746476247406	1.04316010789417	0.990830241484816	1.05163995085289	0.0787556907389313	NA	NA	0.189375987226409	0.090954868387404	66.6468289575284
a1121	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1033	Vismodegib	SMO	8	23	2.30258509299405	NA	5.3791811674898	4.74807798692507	0.631103180564726	0.862638612536461	0.804728244230488	0.770501019648553	0.731596257567304	0.784243855101932	0.0788072974546849	NA	NA	0.135079045497978	0.0959001094770056	66.6468289575284
a1122	gain_cnaOV96	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.36905914182825	-4.83813288823976	1.46907374641151	1.30149810310413	1.34388618405045	1.09668100315352	1.12875596430583	1.09315339635664	0.0789550675706519	NA	NA	0.117441831002917	0.103708896444565	66.6468289575284
a1123	loss_cnaOV85	202	GSK-1904529A	IGF1R	6	13	0.0237165266173161	NA	2.96101052474475	2.27578179793249	0.68522872681226	0.740177595389759	0.691896206312652	0.969975466303622	0.925762588708776	0.990363468624977	0.0790133600593331	NA	NA	0.727201102250059	0.0870797310129625	66.6468289575284
a1124	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	3.71104582793437	1.28341063218738	2.42763519574699	3.39265270147124	1.9358411270123	1.12449230155172	0.715556648251746	1.25404670965623	0.0790645014489881	NA	NA	0.581461669448633	0.340151060622434	66.6468289575284
a1125	KRAS_mut	329	QL-XI-92	DDR1	7	25	2.32630161961136	NA	3.85452447930518	4.72383641151008	-0.869311932204893	0.838672120807623	0.983197285273441	0.909282455275352	1.03653371876457	0.884168360944086	0.0792124102616174	NA	NA	0.171182534438709	0.0396521913639737	66.6468289575284
a1126	gain_cnaOV18_(CCNE1)	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	4.6680504732289	3.67712164753099	0.990928825697912	0.832822027500268	0.998343605872051	1.00801837199721	1.18984464024349	0.99257291765027	0.0793395993204186	NA	NA	0.704058396609329	0.0907445055932228	66.6468289575284
a1127	loss_cnaOV55	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.82485148428415	2.23187132196389	0.592980162320263	0.7600982609599	0.859497028396621	0.705460020076629	0.780136191301649	0.689915314106972	0.0793495483897685	NA	NA	0.590607862512696	0.104909212221868	66.6468289575284
a1128	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	3.94251291519115	2.18404818914793	1.75846472604321	2.52253036423037	1.37510854493451	1.19113153232154	0.697103492183225	1.2787824877686	0.0793552273191171	NA	NA	0.221193059760543	0.350247902804395	66.6468289575284
a1129	loss_cnaOV44	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	5.17449635841894	4.18519306366698	0.989303294751961	1.31958369695307	0.809129961976744	1.16017323233323	0.749708636925621	1.22267539362285	0.0793681654726223	NA	NA	0.501588328349921	0.322613563625423	66.6468289575284
a1130	SMAD4_mut	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.53808895755122	4.81803285959223	0.720056097958996	0.712899894612406	0.843276482506749	0.866766093036131	1.01003816019707	0.853879021763462	0.0793912793209097	NA	NA	0.135160898196388	0.134044125515282	66.6468289575284
a1131	PIK3R1_mut	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.80668717146829	1.77872513859594	1.02796203287235	1.51548217791416	1.2599351196522	0.792617531412974	0.67830690974353	0.815884895054048	0.079442704191509	NA	NA	0.831322429314483	0.211779680845819	66.6468289575284
a1132	loss_cnaOV40	257	NPK76-II-72-1	PLK3	7	25	2.32630161961136	NA	2.56588054504924	3.41556872020605	-0.849688175156819	1.33577427182224	1.14672367958905	0.715861377665591	0.636101617676531	0.740970288030785	0.0796081154878622	NA	NA	0.583408786584877	0.161212109566097	66.7265994979051
a1133	loss_cnaOV33_(ZFHX3)	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	-0.498985302043145	0.476702675384062	-0.975687977427207	0.677129204835429	0.881756419844557	1.12252272948541	1.44091846941433	1.10652778416879	0.0797992301111763	NA	NA	0.905118751483069	0.112136693449291	66.7844705027258
a1134	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	3.16505065479189	2.63288497965769	0.5321656751342	0.655794257908423	0.517902398335132	0.988544394284108	0.811482669627938	1.0275404725773	0.0798179308080335	NA	NA	0.118291789840273	0.146821516830032	66.7844705027258
a1135	loss_cnaOV43_(NF1)	1016	Temsirolimus	MTOR	5	26	-1.6094379124341	NA	-0.752568431955342	-2.27489439457105	1.52232596261571	0.675338593954755	1.5529657818498	1.04016390041537	2.25416698563166	0.980270125979469	0.0799176449759177	NA	NA	0.0297874685734762	0.00321848293848265	66.8089879047345
a1136	loss_cnaOV20	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.79770615124293	2.84165344688927	0.95605270435366	0.450105986520116	1.00384115337279	1.00564002059273	2.124061294419	0.95239441134828	0.0801181664476191	NA	NA	0.0745068159617283	0.00435998774239903	66.8711023081281
a1137	gain_cnaOV18_(CCNE1)	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	5.02482567361621	4.44350183856516	0.581323835051053	0.289029106038398	0.59362897627989	1.01891093728035	2.01129859556021	0.979271326501024	0.0801410266810447	NA	NA	0.598090702061593	0.0144256452846863	66.8711023081281
a1138	loss_cnaOV85	293	MP470	PDGFR	7	25	2.99573227355399	NA	5.00332862321183	3.78209867675464	1.22122994645719	1.05297344506949	1.83022136409312	0.7169432005345	1.15979178029186	0.667258054362354	0.0805136398928762	NA	NA	0.605547022632864	0.0370687592227575	66.8711023081281
a1139	loss_cnaOV41	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	5.25403125401777	4.465179033528	0.788852220489771	0.819981153040198	0.917539589194804	0.871525531718212	0.962037014588674	0.859747339275067	0.080615628990857	NA	NA	0.940398896215064	0.100533372349095	66.8711023081281
a1140	loss_cnaOV40	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	0.693147180559945	3.63536644359296	2.55873779336515	1.0766286502278	1.86613153189247	1.37376832490275	0.718159897028684	0.576930742462715	0.783704668910616	0.0806469544538944	NA	NA	0.967357882286583	0.164287845094013	66.8711023081281
a1141	loss_cnaOV41	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.54929718277915	4.60377730314561	0.945519879633538	0.382502016680121	1.26718170364538	0.797843958396638	2.47193436479123	0.746159668272913	0.080716846965929	NA	NA	0.402324712644234	0.00472219297074683	66.8711023081281
a1142	PIK3CA_mut	1019	Bosutinib	SRC, ABL, TEC	7	24	0.693147180559945	NA	0.382089469722993	2.11473893814146	-1.73264946841847	0.941732206284895	1.52966310388405	1.2133213634773	1.83985368330315	1.13270004618599	0.0807223713695266	NA	NA	0.0327073588976418	0.00206574646232338	66.8711023081281
a1143	loss_cnaOV59	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.60928175631305	4.98382213102841	0.625459625284644	0.330340167307434	0.606590134692928	1.06940568373325	1.89338048225469	1.03110748017897	0.0808126673112912	NA	NA	0.0951082735107817	0.0190633396859347	66.8711023081281
a1144	loss_cnaOV44	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	4.03238999200139	2.88192190977034	1.15046808223105	0.568529706119465	0.976265350981494	1.20439315339882	2.02358481860807	1.17843789198748	0.0808499189926013	NA	NA	0.0745756533218666	0.0470772419782958	66.8711023081281
a1145	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	1.60232486410136	0.663992430745891	0.938332433355469	1.87280942087939	0.946761992416351	0.787827973374464	0.501029321453791	0.99109643275881	0.0808898226496964	NA	NA	0.837520699760757	0.241817885472408	66.8711023081281
a1146	loss_cnaOV33_(ZFHX3)	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	3.21916920726156	2.64415967484539	0.575009532416169	0.746665681236409	0.511318418847029	1.06583291036009	0.770103068704065	1.12456252546653	0.0809203564845102	NA	NA	0.118429671319293	0.221957852330645	66.8711023081281
a1147	loss_cnaOV87, loss_cnaOV88	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-1.91908525219453	-3.88103390456115	1.96194865236662	2.19140017774375	1.58847922326359	1.19835330137803	0.895294557467194	1.23511130874959	0.0809329291824254	NA	NA	0.222943264265533	0.257841922637766	66.8711023081281
a1148	SMARCA4_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	3.1228976897849	4.30814830264601	-1.18525061286111	0.573436764208797	0.934334210434316	1.29575932459995	2.06692470179597	1.26855101699654	0.08095006108088	NA	NA	0.0389437336595985	0.0455155613093347	66.8711023081281
a1149	loss_cnaOV102	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	5.44479928567413	4.72785739637633	0.716941889297799	0.233362464359494	0.653260987530805	1.13085909779906	3.07222453819031	1.09748156247275	0.0809786317150169	NA	NA	0.751019723352906	0.00687895229551935	66.8711023081281
a1150	loss_cnaOV84	258	STF-62247	stimulates autophagy	6	25	2.32630161961136	NA	4.97969098446958	4.3718410119192	0.607849972550385	0.687500901718486	0.624094217201258	0.95652413282807	0.884144254983514	0.973971486671164	0.081141605525746	NA	NA	0.0432482374306231	0.0876663624845427	66.8882127241017
a1151	loss_cnaOV85	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.76395017243574	2.15691246715303	0.607037705282715	0.670399687439798	0.914383814725935	0.698114109355936	0.905486259399885	0.66387625798545	0.0811435856000101	NA	NA	0.576225098999598	0.0754307494274325	66.8882127241017
a1152	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	3.22351715166205	2.24440688087867	0.979110270783375	0.800132162642171	0.939921330921701	1.05898623591783	1.22368568156314	1.04169385093457	0.0812108384054663	NA	NA	0.370154228819233	0.151149553564553	66.8882127241017
a1153	loss_cnaOV57_(ZNRF3)	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.62404567086137	2.7461222362318	0.877923434629568	1.42906847808088	0.986005221626423	0.845091618588381	0.614332656618769	0.890384163667437	0.0814236626313834	NA	NA	0.284590563628504	0.310422737896247	66.9743976319194
a1154	KRAS_mut	205	BMS-708163	g-secretase	7	25	2.32630161961136	0.940007258491471	4.64209808686326	5.1795784034402	-0.537480316576933	0.794367953948245	0.510934720705614	0.928558693258519	0.676613795792612	1.051954965665	0.0815139990847307	NA	NA	0.0951858147266151	0.131389558205304	66.9743976319194
a1155	PIK3CA_mut	170	Shikonin	unknown	5	13	2.77258872223978	NA	0.518164379291948	-0.214913885668585	0.733078264960532	0.857320099042988	0.672985174683846	1.01325914289253	0.855081160209419	1.08929333444071	0.0815272369548137	NA	NA	0.548857683662541	0.136321818102393	66.9743976319194
a1156	loss_cnaOV87, loss_cnaOV88	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.97997293131619	0.183216140324385	1.79675679099181	0.198805869216313	1.65528974514041	1.12434731802204	9.03774520377376	1.08546361521704	0.0816597224854304	NA	NA	0.829245059503741	9.57925212725889e-06	66.9982787633902
a1157	loss_cnaOV55	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	4.4489502247673	3.84849593157745	0.600454293189848	0.44085071571576	0.778576489406664	0.829642534264096	1.36203542783175	0.771220684620776	0.0816975302503059	NA	NA	0.50607431929239	0.0170583990697172	66.9982787633902
a1158	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1259	BMN-673	PARP1	8	25	2.30258509299405	NA	2.62721140380729	1.66782727953496	0.959384124272335	1.04879839322868	1.39485247087821	0.724261845039929	0.914745989759681	0.687803294113461	0.081938543651204	NA	NA	0.027299396608217	0.0555814267614171	67.137900777265
a1159	KRAS_mut	203	BMS-345541	IKBKB	7	25	2.77258872223978	NA	2.56450979635811	3.47546161049762	-0.910951814139509	0.431519182389104	1.06870267043917	0.934153773327495	2.11103434404939	0.852390322712644	0.0821684324680605	NA	NA	0.0781257267592775	0.00229147653851928	67.221969977071
a1160	loss_cnaOV102	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	5.2085114360793	4.31639727749159	0.892114158587708	0.611281694515261	0.839016418475143	1.07975339999672	1.45941579241162	1.06328569851954	0.0821828405748345	NA	NA	0.863567189244302	0.108864013132314	67.221969977071
a1161	gain_cnaOV48_(SOX17)	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.21962583854055	5.7789069605879	-0.55928112204735	0.409589145082116	0.596259507045364	0.954944394426661	1.36546861351812	0.937982733086719	0.0824553212112146	NA	NA	0.172615443485283	0.12276415425208	67.2393889560125
a1162	loss_cnaOV83	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.89529886534238	3.93378577755605	0.961513087786325	1.03347639842203	1.07600802474877	0.898245368404276	0.930367727075742	0.893592859598626	0.0824685266464385	NA	NA	0.811206044284696	0.108664924226172	67.2393889560125
a1163	loss_cnaOV16, loss_cnaOV17	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.36340793156228	4.60539976296786	0.758008168594418	0.728556902345126	0.622623135171129	1.19183225001538	1.04042411259092	1.21744298561292	0.0825496303251486	NA	NA	0.953066881074588	0.204265638446506	67.2393889560125
a1164	NF1_mut	306	TG101348	JAK2	4	28	2.32630161961136	NA	3.9039357646846	2.66979045446656	1.23414531021804	1.61256088505607	1.31060153108469	0.918362534570987	0.765332535134094	0.941663259920527	0.0825873048057232	NA	NA	0.611230200026045	0.22505333916734	67.2393889560125
a1165	loss_cnaOV42	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	3.21683235340809	2.64449351111017	0.572338842297917	0.747834515157404	0.511517005311599	1.0602316158643	0.765328198548647	1.11890481910619	0.082613486600612	NA	NA	0.118637684932239	0.224234758030006	67.2393889560125
a1166	loss_cnaOV43_(NF1)	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	4.28804734604176	3.43144867307648	0.856598672965283	1.37740941907354	0.764964778867163	0.986178875995014	0.62189111029997	1.11978838324272	0.0826293301169956	NA	NA	0.126061074255298	0.240470663888519	67.2393889560125
a1167	loss_cnaOV20	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	5.24175698908538	3.64505165919319	1.59670532989218	1.34752012511502	1.65881668502301	0.985960944372034	1.1849213233501	0.962556830003212	0.0827511837201985	NA	NA	0.129058279307434	0.0547814849880817	67.2443442071294
a1168	loss_cnaOV102	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-0.63361811438777	-2.46471824055241	1.83110012616464	0.347770238412241	1.58496849660504	1.19248660486632	5.26525827662714	1.15529118092051	0.0827982300620448	NA	NA	0.108618004015981	0.000117932252997232	67.2443442071294
a1169	loss_cnaOV42	341	EX-527	SIRT1	4	27	2.99573227355399	NA	6.27097138060723	5.69958611567242	0.571385264934814	0.54211175306638	0.532855905890801	1.07036895489384	1.05399903562845	1.07230727597849	0.0828773641307434	NA	NA	0.0949084458469498	0.121556441760148	67.2443442071294
a1170	gain_cnaOV50	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	5.30517952117725	5.78665933171292	-0.481479810535673	0.46254481885211	0.598993822814266	0.820547802390906	1.0409365555765	0.803814316938238	0.0829344008581109	NA	NA	0.172683901061768	0.12574000243869	67.2443442071294
a1171	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.65539124131627	3.52345339039673	1.13193785091954	0.955951561265589	1.18838352728771	0.974959619618235	1.18409540481419	0.95250213834838	0.0829897738261689	NA	NA	0.178943293002448	0.0546566283805339	67.2443442071294
a1172	loss_cnaOV40	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	4.74692176372495	3.27941969173672	1.46750207198823	0.820727100948242	2.16388848023518	0.758115900519874	1.78805119301254	0.678178235797408	0.0831105532411722	NA	NA	0.73588940732616	0.00948180367011923	67.2691227326112
a1173	loss_cnaOV84	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	6	26	2.32630161961136	NA	5.57058354559606	5.04363656901696	0.526946976579097	0.653966620390065	0.529453354321443	0.954339393790397	0.805770447832329	0.99526610281739	0.0833056001091845	NA	NA	0.0087522072864125	0.111008185352252	67.2691227326112
a1174	gain_cnaOV96	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	3.31914244751853	2.04475054370501	1.27439190381352	1.57219710408547	0.994122139898636	1.13981550920148	0.810580238636692	1.28192689073745	0.0833101831420187	NA	NA	0.349505027263662	0.204514953078874	67.2691227326112
a1175	KRAS_mut	260	NG-25	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.68916929268147	2.82236921674715	0.866800075934322	0.900453847347264	1.05520467735975	0.844732894606884	0.962625767537018	0.821452078949421	0.0834093115553577	NA	NA	0.41335219260048	0.0530880143022038	67.2691227326112
a1176	loss_cnaOV52, loss_cnaOV53	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	8	24	2.32630161961136	NA	5.5125663793773	5.01906337637496	0.493503003002343	0.294097148993567	0.605529458908348	0.899074752419048	1.67802715766258	0.814994210012562	0.0834823708436881	NA	NA	0.00875581099831462	0.00523323953068637	67.2691227326112
a1177	loss_cnaOV55	170	Shikonin	unknown	4	14	2.77258872223978	NA	0.5451365301414	-0.170257481271247	0.715394011412647	0.827717300890563	0.716183539786084	0.968869002608774	0.864297521198283	0.998897589333493	0.0836586535229291	NA	NA	0.549425962027086	0.185678051227737	67.2691227326112
a1178	loss_cnaOV42	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.87284664183023	2.95682345116819	0.91602319066204	0.713409280472357	0.888720675940048	1.04892813679052	1.2840079541095	1.030721142718	0.0836999989927455	NA	NA	0.218638355395052	0.0742456669741895	67.2691227326112
a1179	gain_cnaOV49	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	1.63105677154697	2.6276433795259	-0.996586607978932	0.0905908487606479	1.03461790642643	0.995639505750957	11.0009633601296	0.963241213774408	0.0838292985440441	NA	NA	0.374240734554063	1.68858892093614e-05	67.2691227326112
a1180	gain_cnaOV96	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-0.619195858387836	-2.23827085129899	1.61907499291115	0.955450158281609	1.51865398761372	1.10108994531689	1.69456771646057	1.0661250068261	0.0839213685444272	NA	NA	0.0300046990096958	0.0300786507255645	67.2691227326112
a1181	gain_cnaOV72_(ASXL1)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.967287162018711	-0.324453620937461	1.29174078295617	1.80117312057535	1.52872042651544	0.828509184978718	0.717166366852924	0.844981698779653	0.0840318908994673	NA	NA	0.085754476740274	0.250390176567558	67.2691227326112
a1182	loss_cnaOV43_(NF1)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.61248164252654	1.40573780193069	1.20674384059585	2.11434671955081	0.793534467186697	1.20947786948935	0.570740753840135	1.52072013314569	0.0840653915830788	NA	NA	0.423807125179985	0.427469779490279	67.2691227326112
a1183	loss_cnaOV44	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.61248164252654	1.40573780193069	1.20674384059585	2.11434671955081	0.793534467186697	1.20947786948935	0.570740753840135	1.52072013314569	0.0840653915830788	NA	NA	0.423807125179985	0.427469779490279	67.2691227326112
a1184	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.87339005947767	4.37388668639413	0.499503373083545	0.51752306071236	0.530575220195815	0.944502269688881	0.96518089917769	0.941437432564599	0.0841188611556912	NA	NA	0.343055773374783	0.0984782129040466	67.2691227326112
a1185	gain_cnaOV72_(ASXL1)	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.91291547177044	4.32392625988467	0.58898921188577	0.307994692908923	0.786388123067433	0.784102689314044	1.91233558709383	0.748980299433216	0.0841413086519082	NA	NA	0.034500864852507	0.0204718946997106	67.2691227326112
a1186	gain_cnaOV18_(CCNE1)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	5.91108646511924	4.79726343670471	1.11382302841453	0.530145574916457	1.18886928657771	1.01107066101054	2.10097580950298	0.936875938330269	0.0842102107116136	NA	NA	0.783659685798848	0.0178803684135709	67.2691227326112
a1187	loss_cnaOV16, loss_cnaOV17	265	Tubastatin A	HDAC6	6	25	2.99573227355399	NA	5.4477913621902	4.59031790490161	0.857473457288584	0.73698067739199	1.26168896830541	0.72185534170528	1.16349516831702	0.679623487903096	0.0842241617203996	NA	NA	0.402906928767648	0.0476851398516111	67.2691227326112
a1188	loss_cnaOV85	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	7	25	2.32630161961136	NA	5.53803845479382	5.03167131537843	0.506367139415388	0.603164900919271	0.536771312980959	0.919512654311119	0.839516919243218	0.943357305373266	0.0842256028300626	NA	NA	0.00877088587820954	0.075934367280914	67.2691227326112
a1189	loss_cnaOV84	254	AC220	FLT3	6	26	0.0237165266173161	NA	2.10717650806038	2.60396784276551	-0.496791334705129	0.56541701620504	0.609262588584525	0.824992575975941	0.878628199129003	0.815397734922973	0.0844079765902086	NA	NA	0.85152211863055	0.0926931054623532	67.3006008310502
a1190	loss_cnaOV35	155	AP-24534	ABL	3	16	-0.669430653942629	NA	1.87224536453215	0.585358117515498	1.28688724701665	1.25394779618232	1.16398975082907	1.09528788785392	1.02626859821009	1.10558297107001	0.084480746102213	NA	NA	0.551898188099298	0.208021984646872	67.3006008310502
a1191	loss_cnaOV82	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.72062110536596	2.24496289997886	1.4756582053871	2.01742825577185	1.17067071716338	1.18733412017202	0.731455109328053	1.26052371837123	0.084716876352897	NA	NA	0.0955002126420617	0.331962918331576	67.3006008310502
a1192	gain_cnaOV96	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.67094629066376	4.79835029172371	0.872595998940049	0.379630432189852	0.848866547862357	1.0733264449642	2.29854069892813	1.0279542775451	0.0849397442028436	NA	NA	0.135908692960794	0.00745734934913484	67.3006008310502
a1193	KRAS_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	0	NA	-2.98270832197312	-1.72248204621199	-1.26022627576113	2.10194341156479	1.94916789141883	0.636587968371753	0.599552903673539	0.646545780540122	0.084992328812608	NA	NA	0.257627359016771	0.186723054723334	67.3006008310502
a1194	gain_cnaOV26	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	5.16161685352899	3.97254688828063	1.18906996524836	0.567198930824407	1.09850139738607	1.10992106689621	2.09638964502293	1.08244738520843	0.0850063947909417	NA	NA	0.811365253795347	0.0393019376106824	67.3006008310502
a1195	SMAD4_mut	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	3.29224148521781	2.25316497843422	1.03907650678359	1.85324559033439	1.19109320315898	0.817946863435353	0.56067933586509	0.872372123380262	0.085023475125644	NA	NA	0.0955315369249256	0.347556457099395	67.3006008310502
a1196	gain_cnaOV48_(SOX17)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	1.33816542285491	2.96789600381026	-1.62973058095535	2.31526018333878	1.42310181758302	1.08881387178801	0.703908179600426	1.14519605049993	0.0851272049123255	NA	NA	0.967406277644467	0.346483845573106	67.3006008310502
a1197	loss_cnaOV59	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	2.99039911437397	1.36170167228765	1.62869744208632	1.23393914169944	1.56715988264551	1.05959662341151	1.31991715559261	1.03926693129544	0.0851435829256029	NA	NA	0.0664950406858801	0.0686588262754226	67.3006008310502
a1198	loss_cnaOV83	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	3.44313196375231	2.85110813676803	0.592023826984279	0.474670194692781	0.569903272937287	1.06808047692055	1.24723193830919	1.0388145762578	0.0853168044413565	NA	NA	0.836571876451428	0.0818057647640577	67.3006008310502
a1199	loss_cnaOV57_(ZNRF3)	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	5.41640638434338	4.40756986091124	1.00883652343214	0.74039286293503	0.987824949550723	1.04441111583161	1.36256921687894	1.02127054382557	0.0853486337440414	NA	NA	0.172062614286808	0.0624878158394113	67.3006008310502
a1200	loss_cnaOV52, loss_cnaOV53	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.75732567399938	2.1588446125303	0.598481061469089	0.364885279958567	0.95970822185442	0.687397986819506	1.64018965505281	0.62360730880544	0.0854146249702892	NA	NA	0.576797685286792	0.019006525247504	67.3006008310502
a1201	SMAD4_mut	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-0.616821840157188	-2.90724845170052	2.29042661154333	3.29044675180846	1.52797735077366	1.2544282852879	0.696083779591478	1.49899251476707	0.0854158267445086	NA	NA	0.305838035177257	0.35075878760379	67.3006008310502
a1202	loss_cnaOV57_(ZNRF3)	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	2.98932277464124	1.36185543510661	1.62746733953463	1.2350600361834	1.56722743079204	1.05869165248567	1.31772326191028	1.03843724756154	0.0854307461200702	NA	NA	0.0665195291184906	0.0689818186164318	67.3006008310502
a1203	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.89684924980271	4.79159336405777	1.10525588574494	0.559082107861649	1.24474033625077	0.939335838952533	1.97691156666105	0.887940925152332	0.0855478684774949	NA	NA	0.351063474532572	0.0070611387212132	67.3006008310502
a1204	loss_cnaOV55	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	7	25	2.32630161961136	NA	5.53682330357687	5.03201155771917	0.504811745857693	0.30889632093204	0.596304925108506	0.916255198012347	1.63424330964679	0.846566453842111	0.0855608731198969	NA	NA	0.00879766188491721	0.00677393034007195	67.3006008310502
a1205	loss_cnaOV85	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	7	24	2.30258509299405	NA	2.30741091486992	1.14699573226495	1.16041518260497	2.47486503430191	0.918910456683885	0.833790354594924	0.468880188018934	1.2628163866941	0.0855792157435685	NA	NA	0.455624845093287	0.266242603922074	67.3006008310502
a1206	gain_cnaOV26	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.30620907737588	1.34741575634807	1.95879332102781	2.30851759019486	1.8047370815833	1.0630521832822	0.848506993989363	1.0853621510948	0.085628295771174	NA	NA	0.772770586563217	0.27652599481162	67.3006008310502
a1207	TP53_mut	1133	JNJ-26854165	MDM2	23	10	2.30258509299405	NA	3.23360115805739	2.68664400158786	0.546957156469526	0.937679185927398	0.757415342536811	0.615168539124655	0.583309477994402	0.722136357361871	0.0856592240349908	NA	NA	0.218923171038995	0.0913103743294044	67.3006008310502
a1208	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.77892663701343	2.94087976664755	0.838046870365888	0.670869403492314	0.898799358942244	0.960247578710137	1.24919524724679	0.932407062853435	0.0856836185465368	NA	NA	0.218926673381829	0.0460123370491075	67.3006008310502
a1209	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	3.21386674609485	2.35685164270665	0.857015103388203	0.949681233557937	0.670931343692609	1.20802797704497	0.902423964067854	1.27735141821135	0.0858014934091969	NA	NA	0.728322020188669	0.253767329159109	67.3374432792211
a1210	NF1_mut	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	4.76203587509323	3.17696752816939	1.58506834692384	0.403366439733122	1.67387166136711	0.99496542535806	3.92959897202295	0.946947357737839	0.0859754508993321	NA	NA	0.614028780014268	0.000363932571020869	67.3790226482282
a1211	gain_cnaOV96	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	3.42258025777861	2.41490174721736	1.00767851056125	1.22797018562217	0.957575401892309	1.02096589040445	0.820605029633264	1.05232288608284	0.0859964995151263	NA	NA	0.374570458588247	0.199545641917149	67.3790226482282
a1212	loss_cnaOV102	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	5.51880657539082	4.42922333654014	1.08958323885068	0.908580817535588	0.944618594670618	1.15625870348416	1.19921444281207	1.15346367835434	0.0861077864048121	NA	NA	0.304681195574661	0.163100678299033	67.4074956515774
a1213	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.91340702663471	2.4831407124641	1.43026631417061	1.64303666968334	1.16706422113055	1.16032994724452	0.870501760892694	1.2255249439359	0.0861749255002116	NA	NA	0.936024476315755	0.266558955393357	67.4074956515774
a1214	PIK3R1_mut	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	2.83691948437479	3.59694462025639	-0.760025135881604	0.785110645896694	0.87970666642187	0.875524141766846	0.968048439864881	0.863952911682413	0.0863537157555577	NA	NA	0.785252519804633	0.098586270619203	67.4766674044855
a1215	gain_cnaOV72_(ASXL1)	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.64448340743974	-4.79732929333435	1.15284588589461	1.6495475012394	1.34112487494669	0.837678125404359	0.698886140004099	0.859611142430292	0.0864055873025809	NA	NA	0.118375933501792	0.260089526042509	67.4766674044855
a1216	loss_cnaOV43_(NF1)	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	3.38419438312613	1.89084133457567	1.49335304855047	1.21776605278571	1.25078723355836	1.19783762190796	1.2263053688632	1.19393051710484	0.0865233023299036	NA	NA	0.882313164525455	0.151836862663875	67.4825721362038
a1217	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	5.04562572590741	4.39046054877975	0.65516517712766	0.629317121453165	0.667763102438907	0.988290648774921	1.04107318042581	0.981134139839061	0.0865553923273753	NA	NA	0.0693829687841032	0.0799548509035314	67.4825721362038
a1218	gain_cnaOV48_(SOX17)	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	3.73610233845296	4.52557961781897	-0.789477279366011	0.439505186884232	0.990330000041725	0.81942218777587	1.79628660349341	0.797186068616269	0.0868423753076422	NA	NA	0.0248041565544152	0.0578539134367593	67.564636284263
a1219	loss_cnaOV102	292	Masitinib	KIT	3	29	2.99573227355399	NA	5.07281406020062	3.90393831970755	1.16887574049307	0.476785129662251	1.02578830869619	1.17048794084989	2.45157759286891	1.13949021507055	0.0868736098926818	NA	NA	0.0903088340674442	0.0222729432841909	67.564636284263
a1220	PTEN_mut	333	T0901317	LXR	3	29	2.32630161961136	NA	3.09186991207997	4.92522918306396	-1.83335927098399	2.51678548323757	0.765786780361429	1.86186411250374	0.728452735918351	2.39408581866444	0.0869059858088756	NA	NA	0.00359289831938473	0.333999249879426	67.564636284263
a1221	loss_cnaOV43_(NF1)	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	4.08933200377585	3.05167014378673	1.03766185998912	0.65339431346283	0.996578074419449	1.09151338864058	1.58810971967259	1.04122485395196	0.0871148555998267	NA	NA	0.536622342097761	0.0388491408524509	67.564636284263
a1222	loss_cnaOV85	298	OSI-930	KIT, VEGFR, PDGFR	7	25	2.32630161961136	NA	5.10418934010621	4.26883162205462	0.835357718051589	0.981439406248347	0.91164682344852	0.902088599192658	0.851155672712215	0.916317258575696	0.0871985824960657	NA	NA	0.0248194877789953	0.0736001986355031	67.564636284263
a1223	gain_cnaOV26	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	2.88032822741553	0.470199499215198	2.41012872820033	1.70495347786943	2.24581512498081	1.08864844178167	1.41360380766056	1.07316434972399	0.0872575130121707	NA	NA	0.943353545151622	0.116623476875724	67.564636284263
a1224	loss_cnaOV44	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.71001758295037	4.50578634259393	-0.795768759643551	0.512798192413235	0.716017707054309	1.12987767069775	1.5518166238041	1.11138139714077	0.087347159979005	NA	NA	0.50562098679757	0.0950838045184536	67.564636284263
a1225	RB1_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	1.13831299060246	2.80678960637948	-1.66847661577702	3.14128148964785	1.48616647702761	1.01487321504698	0.531145209773629	1.12267141102122	0.0874079334269576	NA	NA	0.625342840800621	0.455350933891748	67.564636284263
a1226	loss_cnaOV44	1061	SB590885	BRAF	3	30	1.6094379124341	NA	5.07260034848114	3.81303377183372	1.25956657664741	0.754862443251857	1.26541538158212	1.01672870636241	1.66860411179201	0.995377956503586	0.087613955907661	NA	NA	0.556379982781503	0.0769633162704586	67.564636284263
a1227	loss_cnaOV36	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.28928521941959	4.32463344807913	0.964651771340455	0.779286668883174	0.922016052975106	1.0563480009905	1.23786510132778	1.04624183952956	0.0876326192659635	NA	NA	0.776932362479753	0.152061205954854	67.564636284263
a1228	loss_cnaOV36	1248	FK866	NAMPT	3	29	0	NA	1.11995910694895	-2.00094225160139	3.12090135855034	2.71360603657032	2.60991944359616	1.19256760561626	1.15009375586988	1.19578455427349	0.0877787523190346	NA	NA	0.0362567119220899	0.175746565950082	67.564636284263
a1229	loss_cnaOV16, loss_cnaOV17	299	OSI-027	MTORC1/2	6	26	2.99573227355399	NA	2.68842715389456	1.26396620164824	1.42446095224632	1.56069151424989	1.8996581580688	0.77102596930098	0.912711409807949	0.749851201489026	0.0878174284458916	NA	NA	0.772928272419467	0.0864217285424311	67.564636284263
a1230	loss_cnaOV54	341	EX-527	SIRT1	10	21	2.99573227355399	NA	6.06894553207408	5.63253596784969	0.436409564224397	0.392504255879549	0.57985733151807	0.825182455888695	1.11185944531088	0.75261541159077	0.087852018802541	NA	NA	0.0954475262623876	0.020996786273605	67.564636284263
a1231	loss_cnaOV43_(NF1)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-1.03104997750547	-2.5245411311503	1.49349115364483	0.680160127274526	1.62075199495734	0.974747617989536	2.19579345179995	0.921480373488069	0.0878723448330996	NA	NA	0.10917022460751	0.00380082457998878	67.564636284263
a1232	gain_cnaOV96	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-0.877522686177991	-2.49421761431117	1.61669492813317	1.79706313828308	1.50430331948654	1.05316860824808	0.899631678872324	1.07471339535766	0.0879744713482482	NA	NA	0.109180996150694	0.168704525107391	67.564636284263
a1233	loss_cnaOV83	255	CP724714	ERBB2	5	27	2.32630161961136	NA	5.05921681818432	4.29578302080119	0.763433797383139	0.824414948258071	0.927574138855113	0.834817196417374	0.926030998098978	0.823043426291974	0.0880483982622725	NA	NA	0.776961396033901	0.111291193607144	67.564636284263
a1234	loss_cnaOV84	1008	Methotrexate	Dihydrofolate reductase (DHFR)	6	25	-1.6094379124341	NA	1.3811089707115	0.370009478437363	1.01109949227414	0.783597915042905	1.21341936727981	0.87858827568858	1.29032948258773	0.833264672988345	0.0881368917162252	NA	NA	0.409662988877149	0.0275818373166798	67.564636284263
a1235	loss_cnaOV83	1003	Camptothecin	TOP1	5	26	-2.30258509299405	NA	-2.36369868303242	-3.94645044881283	1.58275176578042	1.72877373541135	1.62114722045007	0.967207921950788	0.915534365984461	0.976315874224557	0.0881538525873699	NA	NA	0.224076209388645	0.112133162956365	67.564636284263
a1236	loss_cnaOV81_(RB1)	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	5.31440199268707	4.32830385576288	0.986098136924187	0.42401084364056	0.973714463333228	1.05642743997818	2.32564367566061	1.01271797231867	0.0881901449770848	NA	NA	0.0248618458218539	0.0069789221684823	67.564636284263
a1237	SMAD4_mut	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.7497032111671	2.72817115904527	1.02153205212184	1.277513013897	0.991172856445676	0.998156818040945	0.799625554502725	1.0306295672634	0.0882119011638868	NA	NA	0.285663278369273	0.208779608157778	67.564636284263
a1238	loss_cnaOV83	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	3.3152200160464	2.39808470072093	0.917135315325476	0.698855530170313	1.02280722201497	0.929215238392605	1.31233892518811	0.896684434353802	0.0885173034732328	NA	NA	0.374942801843684	0.0391401512146163	67.564636284263
a1239	gain_cnaOV72_(ASXL1)	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	2.76730559217018	1.56885697906575	1.19844861310443	1.91004984667449	1.51224199522399	0.769167364193528	0.627443632003115	0.792497905024068	0.0886250508825733	NA	NA	0.0331504212502152	0.303356521793406	67.564636284263
a1240	loss_cnaOV42	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	2.94290662883156	1.50370846379951	1.43919816503205	0.645856663161099	1.4741230146807	1.01831670620311	2.22835537220906	0.976308049395586	0.0886668102266787	NA	NA	0.305282674664142	0.00875351286976636	67.564636284263
a1241	loss_cnaOV58	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.12555014889927	0.549902119241515	0.575648029657752	0.61685613907242	0.578423542927948	0.986215233634256	0.93319656431298	0.995201590073347	0.0887195230977183	NA	NA	0.0114312064091555	0.106622250652956	67.564636284263
a1242	BRCA1_mut	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	2.60895007767277	1.06172248776242	1.54722758991035	0.517549974825532	1.43717093246155	1.14506457922971	2.98952307056324	1.07657868313569	0.0887296116605783	NA	NA	0.842596731360683	0.00994032549556715	67.564636284263
a1243	loss_cnaOV85	1375	Temozolomide	DNA akylating agent	7	26	3.40119738166216	NA	6.34788862162372	5.83935077474161	0.508537846882114	0.693266570231956	0.670569573147147	0.753364733467769	0.733538682980149	0.758367017005292	0.0887974833442981	NA	NA	0.904711626492183	0.115892887705655	67.564636284263
a1244	gain_cnaOV94	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	4.67844268705135	3.59994571069224	1.0784969763591	1.13223164379295	0.859067126608382	1.20130700940662	0.952540924175338	1.25542806022276	0.0888763683869199	NA	NA	0.790814349435568	0.234387378366436	67.564636284263
a1245	loss_cnaOV85	1047	Nutlin-3a	MDM2	7	26	2.07944154167984	1.38629436111989	4.75721580241616	3.47590793775764	1.28130786465853	0.77976184251371	1.60019338202214	0.867274648410333	1.64320411028063	0.800720637301574	0.0889104198559673	NA	NA	0.147994316134183	0.00723332973243861	67.564636284263
a1246	gain_cnaOV48_(SOX17)	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	3.47302122604259	4.27192862648142	-0.798907400438833	0.668332822732761	0.969017817387462	0.839248756486423	1.1953735822403	0.824450682024342	0.0889139420433277	NA	NA	0.0394291204393713	0.158663100160418	67.564636284263
a1247	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.97640404473275	5.11340564531099	0.86299839942176	0.709374170878098	0.674949775571582	1.27124478206831	1.21656304225667	1.27861128435953	0.0889870181155173	NA	NA	0.100812600695587	0.156138070900127	67.564636284263
a1248	loss_cnaOV16, loss_cnaOV17	1264	SGC0946	Q8TEK3 (DOT1L)	6	27	-0.693147180559945	NA	2.52203092234432	2.02493020620608	0.497100716138237	0.442309023041265	0.542660552790551	0.941894246735774	1.12387649865298	0.916043581170532	0.0890340786451256	NA	NA	0.0346030528849228	0.0418768955846353	67.564636284263
a1249	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	5.10413967573377	4.21338255791193	0.890757117821845	0.60801250591693	0.770960801347344	1.17074836835905	1.4650309149127	1.15538574239461	0.0891258788120967	NA	NA	0.204611565193784	0.109065451418222	67.564636284263
a1250	loss_cnaOV52, loss_cnaOV53	1243	piperlongumine	Increases ROS levels	8	24	2.30258509299405	NA	2.01893701977531	1.47965330055914	0.539283719216179	0.646755588310956	0.645471694467726	0.835099908986998	0.833829237756652	0.835487789531789	0.089232237466467	NA	NA	0.189714196006398	0.0635683705733538	67.564636284263
a1251	gain_cnaOV72_(ASXL1)	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.12358107636199	2.99551768191534	-0.871936605553353	1.11229945952714	1.07636183722911	0.806435840235663	0.783904548442401	0.810077592306678	0.0892787340547451	NA	NA	0.369957072868877	0.161400779654818	67.564636284263
a1252	loss_cnaOV41	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.60359580599698	2.74904364549814	0.854552160498843	1.38411703886287	0.995743827712432	0.820799945624877	0.617398772289448	0.858204828105282	0.0894148651603199	NA	NA	0.285844077187772	0.30875548895655	67.564636284263
a1253	gain_cnaOV96	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	3.69753247906231	2.25995483451969	1.43757764454261	0.940470653830099	1.42678164322142	1.03732461257738	1.52857257022112	1.00756668083899	0.0894597550729667	NA	NA	0.220021067494727	0.0433007483291425	67.564636284263
a1254	loss_cnaOV34	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	2.40550633164883	3.40772668908963	-1.0022203574408	0.554666325425787	1.0841674116855	0.97357240002384	1.80688877528567	0.924414759785757	0.089466206890003	NA	NA	0.0520582220208391	0.0104295849748524	67.564636284263
a1255	loss_cnaOV33_(ZFHX3)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	2.16133309989705	2.96411507574512	-0.802781975848071	0.326114412051335	0.795938210182156	1.05337731363292	2.46165746186556	1.00859836301156	0.0895276181017673	NA	NA	0.0150292815799623	0.00509681595360799	67.564636284263
a1256	BRCA1_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.800340927336086	-0.488829767257438	1.28917069459352	0.36197837378332	1.4162286387874	0.95447437738872	3.56145777748927	0.910284299643405	0.0895354529783242	NA	NA	0.884162000207526	0.000662759360030014	67.564636284263
a1257	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	4.87771384053495	2.3502890349777	2.52742480555726	2.23869773985838	2.22644548182568	1.13476640231236	1.12897099083914	1.13518378338407	0.0895990101542339	NA	NA	0.365161171675206	0.180689985767767	67.564636284263
a1258	gain_cnaOV26	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	4.41825857572896	3.10674503770031	1.31151353802865	0.777355459428521	1.20012556386793	1.11459177769047	1.68714778049262	1.09281360010508	0.0896038754380753	NA	NA	0.584664365918487	0.0766881543988969	67.564636284263
a1259	loss_cnaOV34	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.41636809245742	5.77038921699713	-0.35402112453971	0.666723407562023	0.423373989791359	0.764185262250116	0.530986493835941	0.836190066173345	0.0897265100383582	NA	NA	0.360897503981611	0.307962819641128	67.564636284263
a1260	loss_cnaOV85	286	KIN001-236	TIE2	7	25	2.32630161961136	NA	5.18016198659712	4.68724513783025	0.492916848766866	0.573424281721775	0.650440503636706	0.775289734701947	0.859602330209709	0.757820040435516	0.0899628288285856	NA	NA	0.751735634034902	0.0777214004741666	67.564636284263
a1261	gain_cnaOV4_(KRAS)	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	4.41507089652049	3.85798214348656	0.557088753033936	0.444510301084088	0.785372245525078	0.76308835959845	1.25326398887784	0.7093308379665	0.0899978826717579	NA	NA	0.507230932736939	0.0264084778368394	67.564636284263
a1262	loss_cnaOV35	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.43415195353333	3.73552331361715	0.698628639916183	1.11594931977031	0.781814147023023	0.83919495746227	0.626039756052703	0.893599383659668	0.0901087868413478	NA	NA	0.920442124554605	0.240364570031818	67.564636284263
a1263	loss_cnaOV83	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	3.05668688640296	2.2236209335622	0.833065952840756	0.700054877893569	0.974396105562684	0.893971968591773	1.19000092585229	0.854956160112818	0.0903483515440374	NA	NA	0.372742420366438	0.0975714766784118	67.564636284263
a1264	BRCA1_mut	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.75941580078992	3.85263226718463	0.906783533605289	0.52010005973663	1.18512607241893	0.79924270846797	1.74347900299121	0.765136768744339	0.0905388954559363	NA	NA	0.0702089576734746	0.028276314428208	67.564636284263
a1265	ARID1A_mut	1016	Temsirolimus	MTOR	9	22	-1.6094379124341	NA	-3.1513993477588	-1.57034101312704	-1.58105833463176	1.64154979564104	1.27823807321619	1.13909658665946	0.963149786153356	1.23690442943358	0.0907167479231139	NA	NA	0.0303512229065526	0.0235813622819712	67.564636284263
a1266	SMAD4_mut	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	1.83672676919511	2.88735679150217	-1.05063002230706	1.129279141761	1.20258595093033	0.877104967575576	0.930354580594402	0.87364235503856	0.0907804258417672	NA	NA	0.0815469397320869	0.242384745039408	67.564636284263
a1267	loss_cnaOV38	275	I-BET	BRD2, BRD3, BRD4	8	23	2.99573227355399	NA	3.26973404332104	4.14598743931617	-0.876253395995131	1.12979783902989	1.1775134099719	0.751391239152621	0.775584237926613	0.744155768057062	0.090789389454046	NA	NA	0.685528129457432	0.0848545675141218	67.564636284263
a1268	loss_cnaOV40	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	2.94687734619792	1.57109633133416	1.37578101486376	1.31986584093937	1.63081217089076	0.87053197574795	1.04236428596757	0.84361708811156	0.0908332267146754	NA	NA	0.308101860382877	0.131620704480135	67.564636284263
a1269	loss_cnaOV43_(NF1)	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	5.30647966356813	4.39056234537213	0.915917318195996	0.802793892917204	0.989097930690581	0.947825964287516	1.14091216472477	0.926012773635579	0.0908402219380757	NA	NA	0.172795356498624	0.0618083719296989	67.564636284263
a1270	loss_cnaOV102	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.961622217915764	-0.461985539828955	1.42360775774472	0.690257569585772	1.38855750838222	1.05108739537999	2.06242976603507	1.0252422021781	0.0908750798804416	NA	NA	0.884208552768467	0.0406683399256398	67.564636284263
a1271	loss_cnaOV83	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	5.01856803445096	3.6669696697706	1.35159836468035	1.34735848440785	1.54535754875618	0.889454088880467	1.003146809347	0.874618541041341	0.0910556213151221	NA	NA	0.703056263504281	0.0902722531194147	67.564636284263
a1272	KRAS_mut	1004	Vinblastine	Microtubules	7	24	-2.30258509299405	NA	-4.45737764431926	-2.98204941062314	-1.47532823369612	1.0205997611167	1.86445425631941	0.855714153382097	1.44555024398779	0.791292266192976	0.0911514613499033	NA	NA	0.122713928774655	0.0136288951960682	67.564636284263
a1273	loss_cnaOV58	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	0.129369071605963	-1.58531907849952	1.71468815010548	1.70419352444303	1.78493604756428	0.966357581315547	1.0061581184953	0.96064402556346	0.0912341320948715	NA	NA	0.0627423862559511	0.0881197969123997	67.564636284263
a1274	loss_cnaOV57_(ZNRF3)	255	CP724714	ERBB2	4	28	2.32630161961136	NA	5.14612567130733	4.31063296311873	0.835492708188603	0.697287984625465	0.935827966282281	0.91332900783501	1.19820321963152	0.892784505583569	0.0912442094171843	NA	NA	0.777179600219368	0.0890451246440424	67.564636284263
a1275	loss_cnaOV43_(NF1)	255	CP724714	ERBB2	5	27	2.32630161961136	NA	5.05288722679732	4.29695516735434	0.755932059442979	0.697469282875356	0.944439386223894	0.825823024157325	1.08382129221033	0.800402937943308	0.0912925391116046	NA	NA	0.777182834605306	0.0742407508362851	67.564636284263
a1276	loss_cnaOV42	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	4.54233823834702	2.30793466366321	2.23440357468381	1.70690617054203	2.27688623685532	1.00356592426233	1.30903714172776	0.981341772160655	0.0913392597771136	NA	NA	0.365417731590373	0.070041812437166	67.564636284263
a1277	loss_cnaOV83	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.39800880390438	2.19716808199792	1.20084072190646	1.39238433092541	1.21639860718398	0.968021696863525	0.862434814321958	0.987209879076125	0.091415835303815	NA	NA	0.0961592944656505	0.128510816553025	67.564636284263
a1278	loss_cnaOV16, loss_cnaOV17	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.52443257561929	2.87286576122949	0.651566814389796	0.56234881745555	0.555266692843278	1.17166240862579	1.15865241317289	1.17343039441715	0.0914378845494578	NA	NA	0.837149851226529	0.169223255482795	67.564636284263
a1279	loss_cnaOV34	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	-1.0718007621883	0.346896110644533	-1.41869687283283	0.868895707246221	1.62787171872576	0.917949752370523	1.63275852441381	0.871504097351931	0.0914517558427907	NA	NA	0.441638104968371	0.0174028645229103	67.564636284263
a1280	gain_cnaOV72_(ASXL1)	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.83121304223018	2.90391730350876	0.927295738721418	0.1180466172976	1.2232671219803	0.800158610590175	7.85533512056235	0.758048444251699	0.0914548046374278	NA	NA	0.0754774882195127	0.000666435771766009	67.564636284263
a1281	loss_cnaOV84	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	6	26	2.30258509299405	NA	1.65194340131122	0.688631708057288	0.96331169325393	1.90767231207208	0.993020203631537	0.806047582493898	0.504967067539812	0.970082672770442	0.0914624479016095	NA	NA	0.838077016954453	0.278115958812205	67.564636284263
a1282	loss_cnaOV43_(NF1)	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.52439431213888	2.87287293563207	0.651521376506812	0.562407337829087	0.555267769788256	1.171564034442	1.15845105972783	1.17334628796348	0.0914631409121061	NA	NA	0.837152144291473	0.169276250780035	67.564636284263
a1283	gain_cnaOV19	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	1.77607354434635	3.54051771227851	-1.76444416793216	1.10220200222509	1.62609993030741	1.10517383914555	1.60083556768192	1.08507732830331	0.0915082491510017	NA	NA	0.614650215423101	0.0875672208465434	67.564636284263
a1284	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.41108243879502	-4.83190721461505	1.42082477582004	1.69052324371059	1.30015738170884	1.05574639345646	0.840464501807981	1.09280983656963	0.091664693918393	NA	NA	0.118986230652758	0.191307847370635	67.564636284263
a1285	loss_cnaOV43_(NF1)	1020	Lenalidomide	TNFA	5	26	1.6094379124341	NA	5.01256208831468	4.28211001778441	0.730452070530278	0.554787890378002	0.751080825402304	1.00452303184626	1.3166330469697	0.972534573944187	0.0917322922043596	NA	NA	0.0349246076924629	0.0383651231267312	67.564636284263
a1286	loss_cnaOV84	211	TL-2-105	CRAF	6	26	2.32630161961136	1.63315443905142	4.07546919153813	4.48615340801774	-0.410684216479612	0.933356594771882	0.529276443796473	0.667415760665145	0.440007837068945	0.7759351871657	0.0918419766516437	NA	NA	0.250854639823617	0.340031414092106	67.564636284263
a1287	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.12193018405631	0.550572483101323	0.571357700954986	0.619080973204166	0.578747993920943	0.977872317735804	0.922912713659767	0.987230551045389	0.091897439495908	NA	NA	0.0115047064288269	0.10964877556007	67.564636284263
a1288	gain_cnaOV49	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	3.10789376166202	4.06196618329138	-0.954072421629366	0.29760300969006	1.17929885031711	0.836474382074961	3.20585609205696	0.809016663903994	0.0919570571561182	NA	NA	0.0703291275194596	0.0054269538294424	67.564636284263
a1289	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.52361559833592	2.87301894447013	0.650596653865791	0.477791992901327	0.565915778460667	1.16956289744292	1.36167341339299	1.14963511997397	0.0919782415477894	NA	NA	0.837198754924519	0.122095598915694	67.564636284263
a1290	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	6.50017282315955	5.43928783073144	1.06088499242811	0.690967128779713	0.950601059100432	1.13398564967075	1.53536246261337	1.11601494893351	0.0920270012283816	NA	NA	0.283616811911704	0.0976146653188023	67.564636284263
a1291	loss_cnaOV41	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.63268502937242	3.52750807110099	1.10517695827143	0.940330642871339	1.19417358232209	0.949030162414292	1.17530675688365	0.925474298403418	0.0920770589954554	NA	NA	0.18014239506236	0.0561941674337749	67.564636284263
a1292	loss_cnaOV20	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	5.03781054106912	4.39185611750087	0.645954423568245	0.63028612012786	0.669036465313625	0.9725834800897	1.02485903296935	0.965499575969212	0.0922456521665565	NA	NA	0.0698419540291779	0.0836216587913223	67.564636284263
a1293	loss_cnaOV58	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.95144795011535	4.05732422575971	0.894123724355634	1.10771130670713	0.890973004190032	0.968906556676965	0.807181184250595	1.00353626894506	0.0923271631227097	NA	NA	0.0396240543044132	0.148736795093273	67.564636284263
a1294	PIK3R1_mut	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	3.29912625789085	4.48802707870452	-1.18890082081367	1.44011428692532	1.21369439142381	0.954767548492994	0.825560048676418	0.979571817431694	0.0923685362657287	NA	NA	0.351269508819691	0.141750754105059	67.564636284263
a1295	gain_cnaOV72_(ASXL1)	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	5.2472188836477	4.71133955309991	0.535879330547795	0.351415739444654	0.67224967544944	0.838818614116564	1.52491556409696	0.797143308681447	0.0924066112074825	NA	NA	0.751916707020469	0.0241031091083835	67.564636284263
a1296	KRAS_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	6	17	2.30258509299405	NA	4.35536913828994	3.67649289425648	0.67887624403346	0.441577919993352	0.926912043993857	0.810816542099518	1.53738720460407	0.732406325316838	0.0924635782364008	NA	NA	0.935941469973614	0.0296272491528078	67.564636284263
a1297	loss_cnaOV57_(ZNRF3)	281	CH5424802	ALK	4	28	1.63315443905142	NA	4.50379957950144	3.84529223772637	0.658507341775068	0.51099632325503	0.718375360647406	0.94017946765946	1.28867334618065	0.916661926129559	0.0924739362204635	NA	NA	0.953834288841138	0.073087107793727	67.564636284263
a1298	loss_cnaOV58	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.77256100093815	2.84614365230084	0.926417348637309	0.5995171621611	0.996608952252511	0.970377714564662	1.54527244107211	0.929569563411449	0.0924817416973369	NA	NA	0.0755917859653652	0.0206730002964054	67.564636284263
a1299	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.19577030277835	4.41912376956783	0.776646533210514	0.862750832365138	0.651549202802928	1.16404609724942	0.900197952961021	1.19199982114846	0.0925531938847204	NA	NA	0.0698659290081965	0.25591708283647	67.564636284263
a1300	loss_cnaOV84	287	KIN001-244	PDPK1 (PDK1)	6	26	2.99573227355399	NA	4.0706767653497	3.42291788208864	0.647758883261062	0.700733850563392	0.903986528869553	0.741650345796954	0.924400730377535	0.716558115164717	0.0927208508938709	NA	NA	0.649422455699483	0.0853474807812733	67.564636284263
a1301	loss_cnaOV102	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	3.12123591749972	1.5994437086131	1.52179220888663	1.35934364112038	1.67270437680391	0.919912239927918	1.11950515149529	0.909779534261971	0.092811613791268	NA	NA	0.210504590938499	0.180596862807644	67.564636284263
a1302	loss_cnaOV56	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.05290623342871	-2.90590124869968	1.85299501527097	1.51645872218361	1.70576372025446	1.09398577589219	1.22192248833702	1.08631400308746	0.0929013991676239	NA	NA	0.683614378374569	0.156438984124802	67.564636284263
a1303	loss_cnaOV1	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	5.15972173118994	3.3657936743101	1.79392805687984	0.435125348936761	1.68915655576989	1.09796246658137	4.12278452924737	1.062025926935	0.0929588038234535	NA	NA	0.685502135438026	0.000938600662670095	67.564636284263
a1304	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	164	JQ12	HDAC	3	16	1.63315443905142	NA	3.67855790003094	1.44051839948447	2.23803950054648	2.2434778518255	2.04758518609587	1.08034707789202	0.99757592825149	1.09301411035003	0.0930150590677693	NA	NA	0.634490241814424	0.217627212563599	67.564636284263
a1305	loss_cnaOV56	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.19473422367705	4.41922737747796	0.775506846199092	0.82306678855108	0.65520723566112	1.16213479448998	0.94221618097881	1.18360543655564	0.0931301873220101	NA	NA	0.0699106900819338	0.24006006959911	67.564636284263
a1306	loss_cnaOV20	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	2.29379456127801	0.400288790855455	1.89350577042256	1.96712931546962	2.255124436952	0.853358800720614	0.962573103624613	0.839645803750766	0.0931576397818749	NA	NA	0.943457874126394	0.100795128735284	67.564636284263
a1307	gain_cnaOV96	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.55537346157283	2.69338247856107	0.861990983011764	0.471969486476198	0.961554423997685	0.931314840574796	1.82637015254425	0.896455740308507	0.0932418441873027	NA	NA	0.964758302770464	0.0219860325778702	67.564636284263
a1308	loss_cnaOV21, loss_cnaOV22	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	1.78460647211993	3.53963499561228	-1.75502852349235	1.5638298028507	1.59984701227696	1.09862925933352	1.12226312626419	1.09699771917224	0.0934077595569327	NA	NA	0.614854036191972	0.182079827726109	67.564636284263
a1309	loss_cnaOV52, loss_cnaOV53	1219	PFI-1	BRD2, BRD3, BRD4	8	24	2.30258509299405	NA	2.76179361148978	2.228183106132	0.533610505357778	0.725964258848804	0.877780839294018	0.631640645297469	0.735036882124127	0.607908582040763	0.0935691550638195	NA	NA	0.592330698911992	0.109658906582228	67.564636284263
a1310	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.03492342235298	3.01193576599109	-0.97701234363811	0.469084796719722	1.13292483463478	0.914365734389681	2.08280539141386	0.862380551445027	0.0935965695017987	NA	NA	0.370585380331562	0.00575390145666319	67.564636284263
a1311	loss_cnaOV56	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.26338818891985	1.35184550342973	1.91154268549013	2.13674101638259	1.82465752566977	1.03488617568828	0.894606632640151	1.04761724246772	0.093701609635349	NA	NA	0.773331387924479	0.257349319693248	67.564636284263
a1312	loss_cnaOV84	1149	TW 37	BCL2, BCL2L1	6	27	1.6094379124341	NA	-0.0757109018424162	-0.888099423360058	0.812388521517641	1.19784920694212	0.795740229726254	0.930345042603809	0.678206001898616	1.02092176714141	0.0937354503567454	NA	NA	0.0345020471400744	0.163838122576476	67.564636284263
a1313	loss_cnaOV54	1164	XMD8-92	MAP2K5 (ERK5)	6	17	2.30258509299405	NA	3.47379406183076	2.72791406379551	0.745879998035247	1.02587348859712	0.70223843178165	0.942492067704715	0.727068207070284	1.06214636550562	0.0939312480324807	NA	NA	0.300379622847203	0.144679407310562	67.564636284263
a1314	loss_cnaOV59	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	3.20206810825174	2.64660268898965	0.555465419262092	0.681740802985917	0.524037141557529	1.02507692018968	0.814775082889628	1.05997337824405	0.0939466265884314	NA	NA	0.119925152445214	0.20206617571548	67.564636284263
a1315	loss_cnaOV83	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.88399989387181	2.62969203262548	1.25430786124633	1.39072046527312	1.51883154622832	0.834583454083755	0.901912276814019	0.825837377661223	0.0939756167858027	NA	NA	0.967494057053103	0.1180967380167	67.564636284263
a1316	gain_cnaOV4_(KRAS)	1038	NU-7441	PRKDC (DNAPK)	7	26	0.693147180559945	NA	3.120672471337	2.37991401542535	0.740758455911656	0.976360831298109	1.00043426057433	0.743867594307902	0.758693335666477	0.740436913352409	0.094034469259299	NA	NA	0.375718927249879	0.10771890373262	67.564636284263
a1317	loss_cnaOV21, loss_cnaOV22	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	5.15377396453793	3.36643093502281	1.78734302951512	0.429577860521404	1.68996210831512	1.09348093976761	4.16069633417726	1.05762313883895	0.0942672525832911	NA	NA	0.685623066057149	0.000879967598167231	67.564636284263
a1318	loss_cnaOV82	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.63155001378065	3.7623587502535	0.869191263527158	1.06331462547144	0.814388080102086	1.04382723092678	0.817435632601952	1.06729369543106	0.094303666988193	NA	NA	0.920540248238321	0.290164024369174	67.564636284263
a1319	loss_cnaOV43_(NF1)	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-0.661542833030972	-2.89886326553669	2.23732043250571	3.01799890238143	1.61380756185397	1.21882846160832	0.741325793969077	1.38636135149562	0.0944236354262128	NA	NA	0.308270757722541	0.326672134288491	67.564636284263
a1320	loss_cnaOV1	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-3.99023719726626	-1.78975932878416	-2.2004778684821	2.14062159452157	1.92872234231884	1.13246275407963	1.02796209947322	1.1408992472377	0.0945048878507408	NA	NA	0.258976033324654	0.210620342316566	67.564636284263
a1321	loss_cnaOV40	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	0	NA	-1.14953221569876	-2.25868934918934	1.10915713349059	1.99171721468787	1.98981661754904	0.557296517663812	0.55688484555495	0.557416760775067	0.0945575611789806	NA	NA	0.258983087688965	0.195733671529406	67.564636284263
a1322	loss_cnaOV35	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-0.662192388432873	-2.89874147389883	2.23654908546596	3.35582866010644	1.5224498576606	1.218315546411	0.666467007703254	1.46904613916326	0.0945593308090547	NA	NA	0.30830546096818	0.367499845355654	67.564636284263
a1323	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.27757446525522	2.65794566651557	0.619628798739657	0.814216509287425	0.518206986491156	1.14115313820722	0.761012324942828	1.19571679829182	0.0946554456196157	NA	NA	0.120000205173304	0.316961053966727	67.564636284263
a1324	loss_cnaOV57_(ZNRF3)	1026	17-AAG	HSP90	4	29	0	NA	-1.90649167245231	-0.341086018405599	-1.56540565404671	2.10328104150029	2.27042137383594	0.694258449344483	0.744268418323256	0.689478029094623	0.0947039658005161	NA	NA	0.0517268574196109	0.238726413146693	67.564636284263
a1325	gain_cnaOV96	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	5.07834728433454	4.29941784320851	0.778929441126031	0.433762064795376	0.75685350273914	1.06689352332343	1.79575279708585	1.02916804679769	0.0948350412633188	NA	NA	0.0350879186626994	0.0237669407092933	67.564636284263
a1326	loss_cnaOV20	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.87343412604219	4.79592949808749	1.0775046279547	0.546627426462436	1.2495302840491	0.912946329300653	1.97118654460479	0.862327741639882	0.0949218861038525	NA	NA	0.352455664102947	0.0074597316279748	67.564636284263
a1327	loss_cnaOV59	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	5.09874846985386	4.40572517641223	0.693023293441636	0.730670201541433	0.65886238934954	1.04034133771469	0.948476196209486	1.05184831407029	0.0949947431576149	NA	NA	0.0700534147190105	0.152116837016752	67.564636284263
a1328	loss_cnaOV87, loss_cnaOV88	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	6.31940681316683	5.66513651493691	0.654270298229926	0.776070995845672	0.559727723376184	1.13454419717921	0.843054696970061	1.16890815106223	0.0950155273459518	NA	NA	0.174284346689852	0.279141833744241	67.564636284263
a1329	loss_cnaOV40	298	OSI-930	KIT, VEGFR, PDGFR	7	25	2.32630161961136	NA	5.09241801418179	4.27212759331346	0.820290420868331	0.854838288351963	0.945993115886991	0.8834782252577	0.959585493590564	0.867120919901412	0.0951016818000224	NA	NA	0.0251447892577356	0.0519917568224541	67.564636284263
a1330	loss_cnaOV43_(NF1)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.73514091608942	0.708902971737396	1.02623794435203	2.08587315150664	0.990835760301021	0.857892264064418	0.491994416635915	1.03572961884243	0.0952528150973883	NA	NA	0.838259249928501	0.337329133513257	67.564636284263
a1331	KRAS_mut	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.19199324442031	1.73276890642718	-0.54077566200687	0.346901270583578	0.7051675750901	0.832576480356906	1.5588748380689	0.766875394033503	0.0952641392740793	NA	NA	0.190506657411555	0.0105587993090977	67.564636284263
a1332	gain_cnaOV19	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.95227413968109	3.79604631172894	1.15622782795215	0.376962226398042	1.05794823456338	1.12503960716016	3.0672246368029	1.09289641040833	0.0954058517589208	NA	NA	0.296936618076222	0.0070282675297933	67.564636284263
a1333	loss_cnaOV44	1262	UNC1215	LMBL3	3	30	0	NA	3.27425436571051	2.73102853842243	0.543225827288081	0.728440964868362	0.44901798634656	1.15074840309134	0.745737614284568	1.20980861303139	0.0954086163956031	NA	NA	0.0962217809792281	0.324620352310121	67.564636284263
a1334	KRAS_mut	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	1.54376712874604	2.69049981526313	-1.14673268651709	1.41534714832414	1.37901062990223	0.827157119979786	0.810213019381779	0.831561890569613	0.0954849781037203	NA	NA	0.220846378250717	0.0875866381773884	67.564636284263
a1335	loss_cnaOV55	1019	Bosutinib	SRC, ABL, TEC	7	24	0.693147180559945	NA	2.78539913221585	1.41377361991438	1.37162551230147	1.38777508602403	1.52737623209555	0.914685385517494	0.988362974746272	0.898027272834813	0.0955482663314088	NA	NA	0.0335077317790349	0.0468317128748933	67.564636284263
a1336	loss_cnaOV84	238	CAL-101	PI3Kdelta	6	26	2.99573227355399	2.32630161961136	5.02698512286212	4.23958445057837	0.787400672283754	0.75702121909808	0.974210747035742	0.836327258583749	1.04013025318084	0.808244699290785	0.0956290056204034	NA	NA	0.493522704651847	0.057493106525625	67.564636284263
a1337	TP53_mut	1061	SB590885	BRAF	23	10	1.6094379124341	NA	4.1809970159055	3.34458828346285	0.836408732442649	1.23277072224746	1.22898797966902	0.679083047788788	0.678478744950884	0.680567057025167	0.0956377581109695	NA	NA	0.557315858564524	0.0901933340612244	67.564636284263
a1338	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	4.26411274466143	3.43572270903725	0.828390035624178	1.50817821004423	0.732623102836151	0.949618204256608	0.549265352136261	1.1307178717369	0.0956962370952066	NA	NA	0.127524671202594	0.290388530655743	67.564636284263
a1339	loss_cnaOV56	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.68468147964438	4.86296120596858	0.821720273675799	0.779507821719345	0.789361559272715	1.0418276765719	1.05415269838261	1.04099352701302	0.0957295797506888	NA	NA	0.943726040057212	0.201503546488195	67.564636284263
a1340	gain_cnaOV95_(MECOM)	157	JNK-9L	JNK	5	14	1.63315443905142	NA	0.672564072284926	-0.282950836705424	0.95551490899035	0.751476517505274	0.96440222597981	1.04001359085996	1.27151665651834	0.990784636586222	0.0958373071016537	NA	NA	0.158918959350921	0.0501311447690342	67.564636284263
a1341	loss_cnaOV58	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.59687187675032	5.05828491423207	0.538586962518253	0.633312164528403	0.54320787003215	0.968566621778814	0.850428892234074	0.991493297927323	0.095845991243507	NA	NA	0.00899176729052196	0.132804227872154	67.564636284263
a1342	loss_cnaOV36	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	4.24514237601555	2.67719830849419	1.56794406752135	1.20897784887114	1.5207505540281	1.04349456070179	1.29691711803106	1.0310330404735	0.0960638875781983	NA	NA	0.967513433113321	0.13894544015351	67.564636284263
a1343	loss_cnaOV16, loss_cnaOV17	1049	PD-173074	FGFR1, FGFR3	6	27	0.693147180559945	NA	3.69568925909955	2.82891450794507	0.866774751154475	0.857645324429919	0.971318770802988	0.908663202641473	1.01064475776234	0.892368990705197	0.0961373379581845	NA	NA	0.0758841894651771	0.0599714124388439	67.564636284263
a1344	loss_cnaOV44	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.76495138325559	4.81944246033672	0.94550892291887	0.755992924599463	0.822249116977131	1.15608795464592	1.25068488361821	1.14990567140392	0.096278989374863	NA	NA	0.137289715584894	0.150447945437826	67.564636284263
a1345	loss_cnaOV33_(ZFHX3)	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	2.91741179718932	1.50735058260554	1.41006121458378	0.691687826438759	1.4754623353022	0.995290475927003	2.03858035472976	0.95567415097382	0.0962816298020834	NA	NA	0.30638472583982	0.0135477944000942	67.564636284263
a1346	loss_cnaOV43_(NF1)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	5	26	2.30258509299405	NA	5.08268835345554	4.40185257460697	0.68083577884857	0.90804074242247	0.890507800132384	0.762459676176025	0.749785496443956	0.764547799297609	0.096291369525661	NA	NA	0.510308260756899	0.178060897829541	67.564636284263
a1347	loss_cnaOV55	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	4.51762036876056	3.25408522887203	1.26353513988853	1.68110117891006	1.62223567448508	0.772998831493701	0.751611595863459	0.778885065691578	0.0963072676346424	NA	NA	0.685807934405514	0.109822589976284	67.564636284263
a1348	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.64894797346938	4.80160930167843	0.847338671790951	0.659427048548774	0.832376190606326	1.03816839817244	1.28496195849976	1.01797562370654	0.096418111261229	NA	NA	0.1373055787155	0.0738938750178404	67.564636284263
a1349	PIK3R1_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	1.11802787222709	2.56281589495986	-1.44478802273277	0.996979012820095	1.52952196317872	0.981730116182041	1.44916593444227	0.944601030592685	0.0964680193129192	NA	NA	0.2236005192859	0.0267097898989185	67.564636284263
a1350	loss_cnaOV54	170	Shikonin	unknown	6	12	2.77258872223978	NA	0.377974809529554	-0.205908956200765	0.58388376573032	0.777093519803564	0.734381092472268	0.78060289766893	0.751368723133755	0.795069170101719	0.096617386500027	NA	NA	0.552566017767213	0.158237184618993	67.564636284263
a1351	gain_cnaOV72_(ASXL1)	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.50374609571728	4.82312069097503	0.68062540474225	0.471866023347829	0.866871378694675	0.815391220623832	1.44241240323535	0.785151547819157	0.0967147821035532	NA	NA	0.137339325709003	0.0530596507848241	67.564636284263
a1352	PIK3R1_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-3.6255325419507	-2.06124067321365	-1.56429186873705	1.60128033588854	1.51046007243696	1.0274607910493	0.976900692325703	1.03563933749883	0.096785790039831	NA	NA	0.110064376653526	0.0944900765885511	67.564636284263
a1353	SMAD4_mut	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.90343374917365	0.774963275323755	1.1284704738499	0.589695574081891	1.27237757287159	0.926738214757257	1.91364921740652	0.886899060396896	0.096834927987786	NA	NA	0.955509764490931	0.01844534172588	67.564636284263
a1354	BRCA1_mut	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.46480033646464	-3.87285199031249	1.40805165384785	0.928039777353336	1.73949522444409	0.841183308695424	1.51723200686877	0.809459913463021	0.0968510903201175	NA	NA	0.225315889150613	0.0447812713683884	67.564636284263
a1355	SMAD4_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.57687475845548	1.41107883454135	1.16579592391413	1.88275403215189	0.860510158247055	1.16141837016404	0.619197146311079	1.35477299453265	0.0968758079625566	NA	NA	0.42647084486855	0.395974091036208	67.564636284263
a1356	loss_cnaOV87, loss_cnaOV88	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	5.41491719769538	4.73094864685689	0.683968550838483	0.261408468284534	0.655929857728213	1.07327428418432	2.61647434502392	1.04274648086212	0.0971513240256118	NA	NA	0.752253531249325	0.0152827586012059	67.564636284263
a1357	loss_cnaOV52, loss_cnaOV53	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	8	24	0.246860077931526	2.32630161961136	0.20155758793128	1.27171780169242	-1.07016021376114	0.884796485433455	1.62652432563673	0.719713392230534	1.20949871680025	0.657942950433407	0.0971895791556311	NA	NA	0.782293839640479	0.0280349703954702	67.564636284263
a1358	loss_cnaOV20	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.86735673938466	0.661105796675584	1.20625094270907	0.49347719598175	1.35943834919051	0.941627073068242	2.44439044505247	0.887315664904808	0.0972291468902207	NA	NA	0.147157505045679	0.00232197574224363	67.564636284263
a1359	loss_cnaOV44	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.96853702403998	2.97778851930262	0.990748504737364	0.841718068424006	0.880780981168378	1.12801274102262	1.17705505192777	1.12485229122808	0.0972781620102377	NA	NA	0.22048081436513	0.168210495631114	67.564636284263
a1360	loss_cnaOV87, loss_cnaOV88	310	YM201636	FYV1	3	29	1.63315443905142	NA	1.54037832196704	2.44138604567303	-0.901007723705983	0.668598134441419	0.842150155626162	1.08332286434956	1.34760729546266	1.06988963629183	0.097377703764137	NA	NA	0.636736085795555	0.128956243497043	67.564636284263
a1361	loss_cnaOV42	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	5.09520492143759	4.40621394171102	0.688990979726564	0.71903186004789	0.660762424014557	1.03355255557354	0.95822037660567	1.04272118795815	0.0973838391787933	NA	NA	0.0702321426147083	0.149005125598186	67.564636284263
a1362	loss_cnaOV70	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.72996416804032	4.50372290275703	-0.773758734716715	0.479661655008151	0.719989372384232	1.09517596989687	1.61313443890687	1.07468077223755	0.0974067004899121	NA	NA	0.506916592960698	0.0856591349771082	67.564636284263
a1363	loss_cnaOV39	192	LFM-A13	BTK	5	14	2.77258872223978	NA	5.16486433169592	4.56802131026379	0.596843021432134	0.589822493255406	0.657740163973455	0.929074685089442	1.01190278135712	0.907414590324792	0.0974696186283747	NA	NA	0.953469029171228	0.0971120188121382	67.564636284263
a1364	gain_cnaOV18_(CCNE1)	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	3.82461615930219	2.07167963947709	1.7529365198251	1.04786339439704	1.76195529403765	1.02753449276902	1.67286740733393	0.994881383061723	0.0974916675715439	NA	NA	0.0971912728329323	0.0313549025081125	67.564636284263
a1365	loss_cnaOV59	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.85540867238254	2.86666181308911	0.988746859293431	0.65838402613967	0.984868406310095	1.03193587253624	1.50177832395295	1.00393804183227	0.0975034852185373	NA	NA	0.0759905334159789	0.0460119826718345	67.564636284263
a1366	loss_cnaOV33_(ZFHX3)	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	5.35177665326221	3.68788968412597	1.66388696913624	1.43562418739417	1.65155128148312	1.02045113795871	1.15899898019718	1.00746915205809	0.0975227426588788	NA	NA	0.130828424758012	0.0969858384105581	67.564636284263
a1367	loss_cnaOV20	163	JQ1	BRD4	4	15	0.940007258491471	NA	1.36210752857799	-0.251114604568496	1.61322213314648	1.91913952659828	1.72021932185202	0.918189367199629	0.840596585494728	0.937800263404586	0.0977598799367392	NA	NA	0.55249572601513	0.195683678205489	67.564636284263
a1368	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	5.29276964855423	4.39310123704137	0.899668411512857	0.785826349224801	0.993603796220325	0.928949738680563	1.14486923529652	0.905459917660541	0.0978592132562995	NA	NA	0.17366631956706	0.0613988602162567	67.564636284263
a1369	loss_cnaOV82	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.26304166699487	4.32734829832997	0.935693368664904	0.798207111782218	0.923755968748264	1.02158674016504	1.17224383853924	1.0129226768979	0.0978803213557024	NA	NA	0.777606733837964	0.167624916451915	67.564636284263
a1370	gain_cnaOV4_(KRAS)	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	4.76276751451165	3.62894495769621	1.13382255681544	1.40197813216514	1.5585036228052	0.742304646043478	0.808730557775835	0.727507167917028	0.0978824322298739	NA	NA	0.703649899446382	0.094404303250242	67.564636284263
a1371	loss_cnaOV58	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	2.7970207467136	1.33719035362897	1.45983039308464	1.15279240085039	1.59153438608832	0.947773678753978	1.26634283155211	0.917247158368106	0.0979289598899543	NA	NA	0.0675112878670755	0.0442573374378921	67.564636284263
a1372	loss_cnaOV21, loss_cnaOV22	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	2.15710556916328	3.34065741768987	-1.18355184852659	0.798039248124609	1.21201265534	0.995495399997629	1.48307473762466	0.976517731322344	0.0980705398083895	NA	NA	0.585612509737097	0.102604398298235	67.564636284263
a1373	loss_cnaOV20	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.7519865092987	5.68958429138701	1.06240221791168	0.428747250883457	1.3049891050167	0.853045043129954	2.47792193587842	0.814108113108034	0.0980852417003571	NA	NA	0.554792011208586	0.00601438946822563	67.564636284263
a1374	loss_cnaOV40	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	4.42836728279944	3.85425915532845	0.574108127470981	0.906205122622717	0.675661213899475	0.789003183724672	0.633529995735856	0.849698215112282	0.098204135817957	NA	NA	0.508264449026603	0.157732746308269	67.564636284263
a1375	BRCA1_mut	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.67149073664617	3.79490513187334	0.876585604772836	0.3799496914992	1.08979739465276	0.840892859926807	2.30710966316098	0.804356487796654	0.0982271817879291	NA	NA	0.297311218421865	0.00823928960327366	67.564636284263
a1376	loss_cnaOV21, loss_cnaOV22	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	3.60396393635098	4.47685202746442	-0.872888091113444	0.663057093321892	0.838206142475602	1.0541808765133	1.31645992465039	1.04137639523305	0.0985399764084197	NA	NA	0.864233994026284	0.135036689040479	67.564636284263
a1377	loss_cnaOV40	221	TAK-715	p38a	7	25	2.99573227355399	2.32630161961136	4.80289992474553	4.13095153793522	0.671948386810317	0.981163898526948	0.822332557622539	0.784566181865371	0.684848258093407	0.817124873120674	0.0986379464947306	NA	NA	0.504191854859624	0.133973225759215	67.564636284263
a1378	loss_cnaOV58	1033	Vismodegib	SMO	5	26	2.30258509299405	NA	5.56458116950316	4.78524373814151	0.779337431361649	0.601433132048513	0.844418980308694	0.955983029209625	1.29580062991739	0.922927420552233	0.0986789039160237	NA	NA	0.137560032889083	0.0410506993543998	67.564636284263
a1379	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	5.21896978045103	4.47167189900332	0.747297881447711	0.883168527857607	0.914155338238403	0.821130013353228	0.846155470757669	0.817473628593331	0.0987075077816248	NA	NA	0.94073813544853	0.137170071013113	67.564636284263
a1380	loss_cnaOV70	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	10.297008868169	8.59256214621003	1.70444672195895	0.903992441447916	1.68473215884638	1.03749790793095	1.88546567848394	1.0117018975444	0.0987413254451293	NA	NA	0.918372255344482	0.0535275940351076	67.564636284263
a1381	loss_cnaOV44	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	1.40355266409865	0.168881215348134	1.23467144875051	0.947041413181947	1.09714958285077	1.13471416520394	1.30371431657055	1.12534468230158	0.0988228900143793	NA	NA	0.131559123832861	0.139165288735947	67.564636284263
a1382	SMARCA4_mut	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-5.3885454340507	-3.5093060279337	-1.879239406117	1.15130451669447	1.67710644951681	1.14153102458977	1.63226963750001	1.12052482217716	0.0988632180270955	NA	NA	0.225585674541392	0.0837659086690167	67.564636284263
a1383	gain_cnaOV26	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.08075014406135	-2.90302084415148	1.82227070009013	2.06895138076367	1.66706341609657	1.07393289950447	0.880770189687838	1.0931022074475	0.0989047967042573	NA	NA	0.684138565324124	0.263120591135565	67.564636284263
a1384	gain_cnaOV18_(CCNE1)	263	FR-180204	ERK	4	28	2.99573227355399	NA	5.37212535952542	4.73171379016971	0.640411569355702	1.18342745056703	0.649558997878602	0.888275346705168	0.541149834786116	0.985917478546562	0.0989062715749265	NA	NA	0.755606818626576	0.361323059752849	67.564636284263
a1385	loss_cnaOV82	306	TG101348	JAK2	3	29	2.32630161961136	NA	4.13554945177303	2.68838715270631	1.44716229906672	0.994181171303559	1.36065384090952	1.08049951762817	1.45563237449892	1.06357859402312	0.0989122750902027	NA	NA	0.613032754439393	0.109123629941972	67.564636284263
a1386	loss_cnaOV102	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	5.11931293489422	3.97692315572561	1.14238977916861	1.32183534324503	1.05614816527853	1.06179549489833	0.864245145968111	1.08165673787573	0.0989151892910733	NA	NA	0.812153301117007	0.269865868187796	67.564636284263
a1387	loss_cnaOV43_(NF1)	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	3.18853885203399	2.36160062284306	0.82693822919093	0.982431940828417	0.671000737609878	1.15701303308662	0.841725716382582	1.23239541008033	0.0989448489499093	NA	NA	0.730232755609443	0.278883581978932	67.564636284263
a1388	loss_cnaOV87, loss_cnaOV88	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	4.0553687763908	2.10703559509573	1.94833318129506	0.654734759133937	1.759808917782	1.13924322793225	2.97575950278286	1.10712768960773	0.0989567851183399	NA	NA	0.097320245393481	0.00848569814418152	67.564636284263
a1389	loss_cnaOV70	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	4.52821196271983	2.85276649187916	1.67544547084066	0.509813031754573	1.60526840834466	1.07647870004995	3.2863920035046	1.04371671561666	0.0990918322169788	NA	NA	0.650216770720605	0.00435045944775146	67.564636284263
a1390	loss_cnaOV43_(NF1)	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.55043767968985	2.03761116797075	0.512826511719104	0.4591361636959	0.540535272252056	0.9662587708648	1.1169377458552	0.948738293400342	0.0991397949362877	NA	NA	0.0350958774061573	0.0654934002203823	67.564636284263
a1391	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	5.13000512485114	3.84531139437826	1.28469373047288	0.650995193626408	1.13649921082616	1.15753219839169	1.97343043858191	1.1303956203709	0.0991675029201123	NA	NA	0.0709122153264453	0.0489114990875332	67.564636284263
a1392	loss_cnaOV58	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	2.32510501937834	3.8909600597996	-1.56585504042126	4.080992671679	1.3639600945849	0.799808083096378	0.383694646473609	1.1480211529926	0.0992006743989132	NA	NA	0.737153210213239	0.441794810662781	67.564636284263
a1393	loss_cnaOV16, loss_cnaOV17	1030	KU-55933	ATM	6	27	2.30258509299405	NA	4.81587927506778	4.00324262692246	0.812636648145322	1.27524516184766	0.920748246929133	0.823691683778341	0.637239546133952	0.882582889357233	0.0993902404245478	NA	NA	0.513190984370183	0.188336309977742	67.564636284263
a1394	SMARCA4_mut	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	3.25389884001452	4.05494321871599	-0.801044378701477	0.81283284979576	0.722600473720195	1.09888127931852	0.985497053794953	1.10855778239035	0.0994052617824652	NA	NA	0.508407686727949	0.224207787839086	67.564636284263
a1395	loss_cnaOV16, loss_cnaOV17	1036	PLX4720	BRAF	6	27	2.30258509299405	NA	5.17396206835318	4.11543026233562	1.05853180601755	1.24955945070409	1.2520322105629	0.845720116526805	0.847124004721107	0.845450937353798	0.0995265688295242	NA	NA	0.352230322729505	0.100406990229894	67.564636284263
a1396	loss_cnaOV21, loss_cnaOV22	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.610129160464786	-1.23213001660317	1.84225917706796	2.37046556987611	1.87354657296261	0.964180550156573	0.777171877322075	0.983300444010219	0.0995732284799793	NA	NA	0.42484288308708	0.308735486118747	67.564636284263
a1397	loss_cnaOV44	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.71569967564845	5.08313631176111	0.632563363887346	0.852174164634598	0.533176700389723	1.12932726338311	0.742293524186552	1.18640473866352	0.0996182857788047	NA	NA	0.00905810117120581	0.326320098601591	67.564636284263
a1398	loss_cnaOV59	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.54166381925243	2.69527346370871	0.846390355543719	0.989498977332423	0.920268974406172	0.912850830971548	0.855372643057694	0.919720624168467	0.0996460063957855	NA	NA	0.964821668044257	0.185838486261595	67.564636284263
a1399	loss_cnaOV56	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.06405424764051	4.93448129693448	-0.870427049293968	1.0545562356395	0.854478550649407	1.0007716458312	0.825396522136275	1.01866459799657	0.0997244126654438	NA	NA	0.651759953048821	0.286346028002368	67.564636284263
a1400	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	1.01617013910806	-0.143870662830836	1.1600408019389	2.13961560850487	1.36650791036347	0.744448430433378	0.542172527311819	0.848908954819257	0.0997268146218319	NA	NA	0.442776460973467	0.214569046193308	67.564636284263
a1401	gain_cnaOV4_(KRAS)	1030	KU-55933	ATM	7	26	2.30258509299405	NA	4.72435847360049	3.99662758700422	0.727730886596267	0.775945451937353	1.03695688417883	0.733737353295516	0.9378634603493	0.70179473968444	0.0997630003273109	NA	NA	0.513233307811495	0.0632267292514916	67.564636284263
a1402	loss_cnaOV54	261	TL-1-85	MAP3K7 (TAK1)	10	22	2.32630161961136	NA	3.93646998438989	3.38247535554377	0.553994628846129	0.849007890513521	0.963652445814359	0.595217610818006	0.652520000151054	0.574890492160751	0.0998506717221634	NA	NA	0.717567171767751	0.117127799887473	67.5757779032888
a1403	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.66376296765687	4.99975371693369	0.664009250723171	0.381939425652972	0.601806539257384	1.12600311409066	1.73851979168678	1.10335997934244	0.100092682696947	NA	NA	0.0970219445930535	0.0709838608059743	67.5769734535487
a1404	loss_cnaOV16, loss_cnaOV17	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	4.21048464610332	3.08912591784265	1.12135872826067	0.743181281277165	0.979795412249763	1.17095364261064	1.50886298741756	1.1444825258835	0.100225624209199	NA	NA	0.5392042262397	0.0970022192383423	67.5769734535487
a1405	loss_cnaOV43_(NF1)	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.92505320614648	3.53745896313855	1.38759424300793	0.875282651152536	1.557362726425	0.93312655396524	1.58530988953203	0.890989760743293	0.100403696608308	NA	NA	0.149288844794748	0.0188943234340042	67.5769734535487
a1406	loss_cnaOV59	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-3.16262152607979	-1.98025920452428	-1.18236232155552	1.65410043659999	1.18885090462704	0.952351831520281	0.714806849326431	0.994542138929051	0.100461439885796	NA	NA	0.593186370743407	0.250095306382722	67.5769734535487
a1407	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-3.52095701711339	-4.40427390784605	0.88331689073266	1.90896861857631	1.03247828965097	0.684026985713733	0.462719440297258	0.855530716322629	0.100677039000887	NA	NA	0.199616400974141	0.245223226103464	67.5769734535487
a1408	loss_cnaOV82	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	4.22588106249138	2.67912443984661	1.54675662264476	1.23626095654412	1.52127824465412	1.02807296130079	1.25115705907967	1.01674800654001	0.100846976900731	NA	NA	0.967556094961249	0.148787923918672	67.5769734535487
a1409	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1028	VX-702	p38	8	23	0.693147180559945	NA	3.80088794468604	3.16212792666001	0.638760018026033	0.695047594138608	0.940770750439975	0.719561112719478	0.919016227683899	0.67897521019579	0.100954621795627	NA	NA	0.500297075142225	0.0585167352798675	67.5769734535487
a1410	PIK3R1_mut	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	1.07756644520457	1.71390159798514	-0.636335152780575	0.347623378740336	0.681174095755334	0.983945530003955	1.83053037193996	0.934174033842202	0.100980983921377	NA	NA	0.191209776787626	0.00972654543483352	67.5769734535487
a1411	gain_cnaOV48_(SOX17)	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	-0.445738646082258	0.47099767653111	-0.916736322613368	0.834725448103538	0.878089654915275	1.0474975286447	1.09824892088309	1.0440122116025	0.101134372513199	NA	NA	0.905770925734341	0.188000086394043	67.5769734535487
a1412	TP53_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	21	10	2.30258509299405	NA	2.43921352111335	1.59462808213258	0.844585438980773	1.36980719595611	0.921549608553348	0.676727913848647	0.616572493905804	0.916483964771691	0.10124125297293	NA	NA	0.673807196480174	0.0537469633290987	67.5769734535487
a1413	gain_cnaOV19	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-0.711667544653311	-2.45691329752586	1.74524575287255	2.15890224879541	1.49261624781848	1.13011959072428	0.808394985852802	1.16925281727524	0.101254869271591	NA	NA	0.110480788139285	0.2945163936175	67.5769734535487
a1414	NF1_mut	290	KIN001-260	IKK	4	27	2.99573227355399	NA	5.51196864955599	4.75221349847641	0.759755151079577	0.926278555764997	0.863930867955791	0.872692250480406	0.820223189181043	0.879416605262974	0.101413713701139	NA	NA	0.651917601297256	0.200849033113604	67.5769734535487
a1415	gain_cnaOV19	1061	SB590885	BRAF	3	30	1.6094379124341	NA	5.02562030520791	3.81773177616104	1.20788852904686	0.250844184323851	1.28383261074773	0.971469881676954	4.81529413290056	0.940845807260936	0.101420326957802	NA	NA	0.557938021120469	0.000367315218800539	67.5769734535487
a1416	loss_cnaOV1	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-3.33549670482275	-2.00238376403517	-1.33311294078759	1.57752138667922	1.21587899629651	1.07302159922782	0.84506806186246	1.09641908845219	0.101586948817596	NA	NA	0.593296972917839	0.278102308542895	67.5769734535487
a1417	gain_cnaOV51_(MYC)	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-0.719918353411682	-2.69113108144826	1.97121272803658	1.98934681535936	2.68008368803339	0.777736799198518	0.99088440126037	0.735504169828006	0.10165204137795	NA	NA	0.382409954337785	0.116275756123942	67.5769734535487
a1418	loss_cnaOV56	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.19260861278621	3.3606319457002	-1.16802333291399	0.58823761934238	1.06281026062781	1.12532311873571	1.98563181698542	1.09899516045698	0.101660680425953	NA	NA	0.0528517735693998	0.0476522799481043	67.5769734535487
a1419	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.78240026268411	2.15153119083058	0.630869071853531	0.718511464863372	0.900952012111254	0.728180562125775	0.878022276197769	0.700224943585151	0.101660802476428	NA	NA	0.578718702237836	0.0782620543987385	67.5769734535487
a1420	loss_cnaOV102	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.32158758304934	5.71456956772986	0.607018015319476	0.417080614650143	0.546200502732466	1.12767643211738	1.45539733566533	1.111346496905	0.101735846063596	NA	NA	0.0967998592899718	0.109777196751293	67.5769734535487
a1421	PTEN_mut	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.16846184558472	1.36166546998164	1.80679637560309	1.78506261792976	1.86164131347377	0.973156824939425	1.01217534749483	0.970539471017464	0.101850222324747	NA	NA	0.773845351907347	0.214046764460168	67.5769734535487
a1422	loss_cnaOV81_(RB1)	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	2.18805684358837	1.5325338570453	0.655522986543075	0.802364460219283	0.633047709761824	1.0054632719427	0.81698906051238	1.03550329056511	0.101976512256259	NA	NA	0.191327851192381	0.201199489918914	67.5769734535487
a1423	gain_cnaOV94	268	YM155	BIRC5 (Survivin)	6	24	1.63315443905142	NA	-5.5551598349875	-3.80015708376418	-1.75500275122331	1.02228963043066	2.43936467494903	0.779076002209134	1.71673731101427	0.719450752585806	0.102145137269305	NA	NA	0.924848539952541	0.0135943345881777	67.5769734535487
a1424	loss_cnaOV41	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.74950486246687	2.94613365495943	0.803371207507441	0.67659483724062	0.903128219031757	0.915844624556067	1.18737413188646	0.88954280309028	0.102147078446065	NA	NA	0.221075028554322	0.0547913776927196	67.5769734535487
a1425	gain_cnaOV72_(ASXL1)	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	3.24102137361997	2.41516543471967	0.825855938900301	0.895294985364184	1.01914335985404	0.820438579441429	0.922440036413655	0.810343246526751	0.102214613281844	NA	NA	0.177124704427322	0.162424540679974	67.5769734535487
a1426	loss_cnaOV41	326	GSK690693	AKT	5	27	2.32630161961136	NA	5.24519597004678	3.94947470032428	1.2957212697225	0.582625256192349	1.47262882567245	0.933953042026171	2.22393597934713	0.879869555134394	0.102270331636394	NA	NA	0.0813870932076224	0.0040273611961943	67.5769734535487
a1427	loss_cnaOV36	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.19433407547923	3.36045344955954	-1.16611937408031	0.586203902730784	1.06309349127961	1.12327882119706	1.98927262109317	1.09691140397887	0.102332638386862	NA	NA	0.0528926475658192	0.0473191493961122	67.5769734535487
a1428	gain_cnaOV26	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	0.420532597725277	1.40189423261931	-0.981361634894032	1.09029237080945	1.19876639271207	0.823399118294357	0.900090343808835	0.818642932317963	0.102350325512727	NA	NA	0.0850500391875611	0.253921192758173	67.5769734535487
a1429	loss_cnaOV42	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.57973595467912	4.98804295983326	0.591692994845856	0.48631538728166	0.599271343996745	1.00465498144163	1.21668573588268	0.987354060515649	0.102391225635141	NA	NA	0.0972241035540085	0.085618986864783	67.5769734535487
a1430	NF1_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	3.42169642006236	2.12673426982343	1.29496215023893	1.57513159209025	1.32204853858538	0.958925197194654	0.822129501269458	0.979511804933098	0.102413182489218	NA	NA	0.512594045482193	0.199333385998345	67.5769734535487
a1431	SMARCA4_mut	309	Y-39983	ROCK	3	29	2.99573227355399	NA	3.75494363589698	5.08939435072008	-1.3344507148231	1.62620392071696	1.14263482227127	1.12988628908254	0.820592484019324	1.16787156212389	0.102471782291747	NA	NA	0.353472035779507	0.288971218285079	67.5769734535487
a1432	gain_cnaOV26	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	3.39856586030089	2.80844334274307	0.590122517557822	1.08982726256081	0.764325034157572	0.746794230315535	0.541482616402154	0.772083199143472	0.102504520208258	NA	NA	0.0153786982786512	0.448890349272021	67.5769734535487
a1433	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1030	KU-55933	ATM	8	25	2.30258509299405	NA	4.678216823777	3.98228367948389	0.695933144293112	1.14204091118656	0.943182254552525	0.7018441483815	0.609376719762208	0.737856486308984	0.102681785622867	NA	NA	0.51355877297606	0.148719912886171	67.5769734535487
a1434	gain_cnaOV50	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	2.32513293478964	3.12704028238884	-0.8019073475992	1.13939824854461	1.17356202510801	0.685347489893648	0.703798999711909	0.683310579622235	0.102729868612344	NA	NA	0.0764137168578623	0.260724089177623	67.5769734535487
a1435	loss_cnaOV83	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-3.48681924915216	-1.72247840034153	-1.76434084881063	2.75040960285828	1.79282659565179	0.908009394943594	0.641482943841198	0.984111264909697	0.102788675319535	NA	NA	0.260036177980933	0.229715528580994	67.5769734535487
a1436	loss_cnaOV55	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	4.14869306602229	5.26723500979724	-1.11854194377495	1.50304675147438	0.993557481523481	1.01617384334187	0.744183068608969	1.12579489820742	0.102805409991201	NA	NA	0.785820188883978	0.23663093646677	67.5769734535487
a1437	loss_cnaOV16, loss_cnaOV17	1243	piperlongumine	Increases ROS levels	6	26	2.30258509299405	NA	2.07557836427951	1.5080655840748	0.567512780204712	0.938578901257436	0.57552896381549	0.872735465101522	0.604651116112243	0.986071624340788	0.102852455268599	NA	NA	0.191430724149336	0.206050913367148	67.5769734535487
a1438	gain_cnaOV96	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.55816990822892	4.85207589603707	0.706094012191851	0.529882758671978	0.813536635346263	0.893171501380292	1.332547626123	0.86793142621207	0.102870012073847	NA	NA	0.943835205262563	0.0663787432160683	67.5769734535487
a1439	SMAD4_mut	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.53737581896576	3.90019809239087	0.637177726574894	0.733203051848347	0.736670103221931	0.865349508826086	0.869033107498148	0.864943105181148	0.102950657223222	NA	NA	0.508819560847614	0.180993018937655	67.5769734535487
a1440	loss_cnaOV102	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.88361158031087	0.193540570789241	1.69007100952163	0.363560538040688	1.66446802891182	1.0504625207505	4.64866461753471	1.01538208013917	0.102998443381032	NA	NA	0.83038027226365	0.00042721575308109	67.5769734535487
a1441	SMAD4_mut	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.48273177372804	5.87335908274951	0.609372690978527	0.778282682362566	0.666255704916328	0.898903602183826	0.782970898348537	0.914622848978164	0.103087808361908	NA	NA	0.905094655397314	0.216840508342296	67.5769734535487
a1442	loss_cnaOV43_(NF1)	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.99309985120361	4.44803409890981	0.545065752293798	0.337349581097685	0.595253340302345	0.948443502963095	1.6157297439654	0.915687011545276	0.103163842690286	NA	NA	0.600678251872193	0.0353925824040341	67.5769734535487
a1443	KRAS_mut	1043	JNK Inhibitor VIII	JNK	7	26	2.30258509299405	NA	3.84247198980097	4.60345728128051	-0.760985291479547	0.796224423731264	1.00236909833249	0.787843000678876	0.955742211364755	0.759186703526177	0.103172904575849	NA	NA	0.356552397323048	0.0564012922401024	67.5769734535487
a1444	SMAD4_mut	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.68684261456165	2.25291827519667	1.43392433936498	1.66603164615538	1.49798844401532	0.946090405277439	0.860682534256764	0.957233245085246	0.103363494848467	NA	NA	0.200277180611298	0.270214947973033	67.5769734535487
a1445	SMAD4_mut	158	PF-562271	FAK	3	15	0.940007258491471	NA	3.44840821827901	2.05764615592666	1.39076206235235	1.60958262724236	1.25274097963077	1.06759738204376	0.864051362641188	1.11017527562822	0.103480988359267	NA	NA	0.726994678393277	0.268877832139562	67.5769734535487
a1446	loss_cnaOV82	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.55578545369849	3.72545613297694	1.83032932072155	1.68576619589255	1.63282371309826	1.1184209431602	1.08575514515668	1.12095954146117	0.103516228376423	NA	NA	0.131467656521768	0.192485356096597	67.5769734535487
a1447	gain_cnaOV19	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	6.03357996903478	4.84390984399646	1.18967012503833	0.575806864231583	1.16361378137603	1.07107551197583	2.06609229402978	1.02239260489978	0.10357313435201	NA	NA	0.785899620293864	0.0372355426189216	67.5769734535487
a1448	gain_cnaOV72_(ASXL1)	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.80029759551763	4.38742232786821	0.412875267649424	0.125311015522679	0.577168511489871	0.765633831434428	3.29480425904538	0.71534614143043	0.103573831573382	NA	NA	0.345836558489878	0.00246067331018163	67.5769734535487
a1449	loss_cnaOV40	1371	PLX4720 (rescreen)	BRAF	8	25	2.30258509299405	NA	5.07872147328617	4.3521339214435	0.726587551842676	0.637456608877593	1.01492259387035	0.770515272348591	1.1398227608339	0.715904401213373	0.103785526292244	NA	NA	0.307090722570695	0.0269011667683268	67.5769734535487
a1450	loss_cnaOV21, loss_cnaOV22	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.74946017887773	3.70286991335	1.04659026552773	0.668678161438002	1.00987886768463	1.05631420328771	1.56516292273854	1.03635227849383	0.103797154035765	NA	NA	0.706183162743891	0.0914157632903427	67.5769734535487
a1451	loss_cnaOV42	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	4.95330251597303	3.9598392948869	0.993463221086133	1.23615215714885	1.05824060781496	0.922132005707078	0.803673896729291	0.938787657314928	0.103864677617431	NA	NA	0.812404297650245	0.20744970249152	67.5769734535487
a1452	gain_cnaOV96	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-1.9694192387224	-2.95469068745297	0.985271448730572	1.44160574787679	1.10145549431772	0.843050422078974	0.683454162264327	0.894517712075954	0.103959467690694	NA	NA	0.344481108675061	0.272671861586828	67.5769734535487
a1453	loss_cnaOV81_(RB1)	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.84203196965103	2.86850687553483	0.973525094116201	0.405141998161337	1.00128533739924	1.01418013663923	2.40292316899844	0.972275392192259	0.103988877283495	NA	NA	0.0764752175183084	0.00582944946085114	67.5769734535487
a1454	gain_cnaOV51_(MYC)	1529	MLN4924	NEDD8-activating enzyme	5	12	0	NA	0.495203436643677	1.68457898987282	-1.18937555322915	1.67762233603343	1.2450137167479	0.865780117539926	0.70896502012563	0.955311204390515	0.104003074136606	NA	NA	0.844047864477905	0.203277511388216	67.5769734535487
a1455	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	293	MP470	PDGFR	3	29	2.99573227355399	NA	5.56683574618844	3.89225034630288	1.67458539988556	1.04389463759364	1.74640674734004	0.980101992718092	1.60417089960895	0.958874788153522	0.104007214325254	NA	NA	0.608130458881061	0.084047211796483	67.5769734535487
a1456	loss_cnaOV59	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	0.323014700153911	-1.25690863573976	1.57992333589367	0.530305675055595	2.01080558617696	0.82503619641276	2.97926914647489	0.785716603710803	0.104033642108083	NA	NA	0.425403131832895	0.00293104916047355	67.5769734535487
a1457	SMARCA4_mut	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.2778083971532	3.99482606147878	-0.717017664325571	1.21796679111702	0.651101653947061	1.01957020497555	0.588700504443129	1.1012376638562	0.10406020646818	NA	NA	0.953986531251844	0.415603945670913	67.5769734535487
a1458	BRCA1_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	4.01741850662438	2.65454146056465	1.36287704605972	1.34001898141749	1.52104036147853	0.905882518895851	1.01705801556486	0.896016358655295	0.104164621001161	NA	NA	0.967584376870873	0.131614696051501	67.5769734535487
a1459	gain_cnaOV95_(MECOM)	186	Bexarotene	Retinioic acid X family agonist	5	13	2.07944154167984	NA	4.3683560230318	3.55328720049067	0.815068822541136	1.21410743483882	0.791017912639068	0.890481872521807	0.671331711801388	1.03040501298109	0.104205304244073	NA	NA	0.792593897751313	0.218928212921112	67.5769734535487
a1460	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	1.71226014671449	0.442861083752129	1.26939906296236	0.857224979448659	1.17879651660224	1.09479469018732	1.48082369669022	1.07686020876722	0.104208636629376	NA	NA	0.411915567049017	0.104845124503978	67.5769734535487
a1461	TP53_mut	310	YM201636	FYV1	22	10	1.63315443905142	NA	2.19040619890865	2.72323939144286	-0.532833192534203	0.819797371283419	0.875209790954176	0.636746025615531	0.649957186005654	0.608806251988218	0.104321133283026	NA	NA	0.637381874887727	0.122526520890212	67.5769734535487
a1462	loss_cnaOV102	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	5.13981820142438	4.09950135316606	1.04031684825832	1.33022463872283	0.895206990912339	1.11795111055544	0.782061027870558	1.16209643000899	0.104416351518395	NA	NA	0.0402607923784943	0.30671574205001	67.5769734535487
a1463	loss_cnaOV58	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.36662933717531	2.20277155819954	1.16385777897578	1.50032300591938	1.20295878032615	0.934581783734367	0.775738140642976	0.96749597576421	0.104416614988806	NA	NA	0.0973061825596637	0.161786967481775	67.5769734535487
a1464	loss_cnaOV84	1030	KU-55933	ATM	6	27	2.30258509299405	NA	4.80708213978955	4.00519754587318	0.80188459391637	1.01776087433979	0.982138459372646	0.811647998154347	0.787890961554741	0.81646796972861	0.104547580287438	NA	NA	0.513761493499179	0.121063156475049	67.5769734535487
a1465	gain_cnaOV51_(MYC)	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-1.83368528637619	-2.50208771595709	0.668402429580893	0.501596143515478	0.750567314184078	0.954862815987312	1.3325509739695	0.890529625990303	0.104579732589487	NA	NA	0.65123222776736	0.0486452066493829	67.5769734535487
a1466	loss_cnaOV54	1001	AICAR	AAPK1 (AMPK) agonist	10	21	7.60090245954208	NA	9.3115247029606	8.48199001827265	0.829534684687957	0.830081846632532	1.30638516885448	0.703391315984179	0.999340833742125	0.634984769013678	0.104584138785336	NA	NA	0.512847334131172	0.041744400504387	67.5769734535487
a1467	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	8	25	1.6094379124341	NA	3.13308168637391	2.09137323716081	1.0417084492131	1.87083499809224	1.36808103630809	0.69612268207081	0.556814711225401	0.761437679177444	0.104641383976817	NA	NA	0.224593110151221	0.177754291771307	67.5769734535487
a1468	PIK3R1_mut	1028	VX-702	p38	4	27	0.693147180559945	NA	2.56803213992199	3.43940434485113	-0.871372204929145	0.471783799722349	0.919060672155493	0.986433602429646	1.84697356170763	0.948111731171672	0.104815957435826	NA	NA	0.500758089789324	0.0210223408555677	67.5769734535487
a1469	gain_cnaOV94	1268	XAV 939	TNKS1 (tankyrase-1)	7	25	1.6094379124341	NA	2.20931874007129	3.03689496469748	-0.827576224626188	1.38087982267701	0.910299365626938	0.809839877415575	0.599310824182965	0.909125344777344	0.104889879875898	NA	NA	0.287959534486114	0.17509067394315	67.5769734535487
a1470	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	230	GSK429286A	ROCK2	7	25	2.99573227355399	2.32630161961136	6.05589272026935	5.3939446607522	0.661948059517147	0.761033424006863	0.988379272416121	0.698784338656462	0.869801560136441	0.669730818918326	0.104924452870878	NA	NA	0.285351215806082	0.081573214342825	67.5769734535487
a1471	PTEN_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.62825315403184	2.15085183940666	1.47740131462518	1.50107515907216	1.33759777394587	1.09477032114124	0.984228741443153	1.10451837121924	0.104989875981478	NA	NA	0.512894288593063	0.2244693408244	67.5769734535487
a1472	loss_cnaOV39	1192	GSK269962A	ROCK1, ROCK2	9	23	1.6094379124341	NA	3.20701045976916	2.13938135412514	1.06762910564402	1.61096112676626	1.29186023082522	0.771316045721043	0.662728037260036	0.826427720405973	0.105023814995338	NA	NA	0.222044859583778	0.10036400259362	67.5769734535487
a1473	loss_cnaOV83	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-3.02859681667727	-1.96196496257632	-1.06663185410096	1.80284106792906	1.13641664286267	0.858349465852587	0.591639425723868	0.938592250298336	0.1050595024951	NA	NA	0.593629810958019	0.262009708338498	67.5769734535487
a1474	SMARCA4_mut	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	1.52012953079377	2.63696289647444	-1.11683336568067	1.40435972520923	0.949153059624426	1.12966268380046	0.795261602588523	1.17666308332041	0.105104179627858	NA	NA	0.177474652430771	0.300446856404275	67.5769734535487
a1475	loss_cnaOV20	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	4.39433931247443	3.5494356283626	0.844903684111836	0.919076841784392	1.02700869711708	0.833828566252359	0.919296021507246	0.822684059525076	0.105379184460433	NA	NA	0.824262824314781	0.113272219250386	67.5769734535487
a1476	loss_cnaOV59	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	4.18455699367886	3.38485582118405	0.799701172494815	1.06773886698851	0.848166696906055	0.917261219138057	0.748966996724887	0.942858491629024	0.105410498531915	NA	NA	0.786381704325194	0.23289474456947	67.5769734535487
a1477	BRCA1_mut	1248	FK866	NAMPT	3	29	0	NA	0.102135031118324	-1.89565010582581	1.99778513694413	1.67755552187729	2.77395877182777	0.735920060795802	1.19089062084126	0.720192800712674	0.105421327724337	NA	NA	0.0371530109990536	0.158415734527345	67.5769734535487
a1478	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-1.54278415682452	-3.50508846052559	1.96230430370107	2.27353250817309	1.69121860770354	1.12928336353749	0.863108091327841	1.16029015690977	0.105446557045669	NA	NA	0.124234887296501	0.270566673605553	67.5769734535487
a1479	loss_cnaOV102	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	3.84027857270454	2.29475964016162	1.54551893254292	1.65762182565423	1.37400888685848	1.1081277922212	0.932371249354739	1.1248245534107	0.105519302446132	NA	NA	0.222103869871455	0.243245474704831	67.5769734535487
a1480	loss_cnaOV20	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.84466451890319	2.18808568554642	0.656578833356778	0.688830696841392	0.899290721007774	0.751851611989984	0.953178823718943	0.730107425795515	0.105578309945312	NA	NA	0.579131027602108	0.107226400998089	67.5769734535487
a1481	ARID1A_mut	283	GSK2126458	PI3K, MTOR	8	24	-2.05572501506252	0.0237165266173161	-3.54224669280868	-2.46216172375448	-1.0800849690542	1.34941425964749	1.81369274453836	0.629189338619664	0.800410223422676	0.595517058943249	0.105598616349494	NA	NA	0.684682761586777	0.0924206793589886	67.5769734535487
a1482	KRAS_mut	1262	UNC1215	LMBL3	7	26	0	NA	2.47340859646101	2.86306765671451	-0.3896590602535	0.295943519996363	0.50398684884947	0.827392274128517	1.31666697840956	0.773153230373047	0.105651980117729	NA	NA	0.0970988677196641	0.018532146227086	67.5769734535487
a1483	gain_cnaOV48_(SOX17)	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	2.60571673825569	4.04153492391725	-1.43581818566156	2.04206099225506	1.64226754397764	0.858275965986345	0.70312208651318	0.87429005762602	0.10581870431943	NA	NA	0.131702895740905	0.346926962577631	67.5769734535487
a1484	KRAS_mut	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	1.10198374172514	2.74766889475118	-1.64568515302604	1.09063896324426	1.5114873923047	1.13017350684494	1.5089183574835	1.08878523327721	0.106098409950442	NA	NA	0.200759636664294	0.0454363525495962	67.5769734535487
a1485	loss_cnaOV16, loss_cnaOV17	1032	Afatinib	ERBB2, EGFR	6	25	-0.693147180559945	NA	1.36469536556476	0.115271941185712	1.24942342437905	1.05582573241395	1.70390501295315	0.775616701930049	1.18336140711637	0.733270584264313	0.106126465866221	NA	NA	0.830524335826394	0.0417936747863684	67.5769734535487
a1486	loss_cnaOV59	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.96054944978187	3.8228346895562	1.13771476022568	0.630389349002539	1.15178940064392	1.02563783709458	1.80478106431505	0.987780196266461	0.106200749650022	NA	NA	0.0714404854909432	0.0231647534396114	67.5769734535487
a1487	gain_cnaOV96	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	2.28999346257761	1.19914283533291	1.0908506272447	1.06730527743132	1.33514052383731	0.832726069759944	1.02206055784718	0.81703057301377	0.10621048482314	NA	NA	0.565262558754476	0.13097666910003	67.5769734535487
a1488	loss_cnaOV42	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.63606413532083	5.07192126881193	0.564142866508897	0.71379349141065	0.539465989403909	1.00857042391225	0.790344649114126	1.04574315636145	0.106235479130255	NA	NA	0.00916894209904811	0.212878009081866	67.5769734535487
a1489	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.76293868875513	1.30292558231282	1.46001310644231	1.65964428446216	1.88391573885252	0.786823183194588	0.879714478645318	0.774988539206961	0.106334609983456	NA	NA	0.774108949283809	0.126887506985045	67.5769734535487
a1490	loss_cnaOV83	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.5071262231681	3.67022136696084	0.836904856207263	1.10535043863884	0.972430424899879	0.84434905021426	0.757139841766248	0.860632118018551	0.106534661913472	NA	NA	0.706385606068056	0.171822003257552	67.5769734535487
a1491	SMAD4_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.70658779989945	5.08407891959721	0.622508880302242	0.802717505353397	0.539767345432013	1.10935679215353	0.775501812469111	1.15329110879059	0.10657947265115	NA	NA	0.0091745239933576	0.309840605351986	67.5769734535487
a1492	ARID1A_mut	1166	QL-VIII-58	MTOR, ATR	6	17	2.30258509299405	NA	-1.2447454175565	-1.15363310171013	-0.0911123158463727	1.5236801865217	1.28248800108515	0.067799625140124	0.0597975327449564	0.0710434060741931	0.106621555728452	NA	NA	0.038367557378767	0.899143081733926	67.5769734535487
a1493	loss_cnaOV20	281	CH5424802	ALK	5	27	1.63315443905142	NA	4.41271702922516	3.83777021585994	0.574946813365218	0.508097216882681	0.728738409640703	0.817463526554088	1.13156851535751	0.788961863076066	0.106717804727264	NA	NA	0.954018776082983	0.0658986241425607	67.5769734535487
a1494	loss_cnaOV102	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	5.16857373991829	4.13539953557955	1.03317420433874	1.14567356053779	0.921400099597546	1.10206445286217	0.901805051566142	1.12130897835806	0.106737954976202	NA	NA	0.192945524183231	0.254968697897013	67.5769734535487
a1495	loss_cnaOV21, loss_cnaOV22	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	2.42279609616871	3.512033167671	-1.08923707150229	0.172029836184938	1.22777342733978	0.917659367092827	6.33167533991793	0.887164559231705	0.10676601729682	NA	NA	0.308069383150695	0.000168369170654547	67.5769734535487
a1496	loss_cnaOV33_(ZFHX3)	305	TPCA-1	IKK	4	28	2.99573227355399	NA	2.39629218639138	3.45789541501129	-1.06160322861991	1.2193430084807	1.18281223049047	0.8947231209947	0.870635433373801	0.897524730683325	0.107066809647963	NA	NA	0.993356133124987	0.180125647681814	67.5769734535487
a1497	loss_cnaOV40	1036	PLX4720	BRAF	8	25	2.30258509299405	NA	5.02501729586354	4.0784100450509	0.946607250812641	1.03452402516205	1.30930009894969	0.755753755064221	0.915017174844598	0.722987229262412	0.107092734306842	NA	NA	0.353166962983983	0.0527725280584233	67.5769734535487
a1498	gain_cnaOV49	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	3.6239651300715	4.52384326172285	-0.89987813165135	0.795997640140143	0.993782996061189	0.916162702977004	1.1305035169362	0.905507676442416	0.107195737334106	NA	NA	0.357040032499671	0.177449394612057	67.5769734535487
a1499	gain_cnaOV72_(ASXL1)	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.60921271600703	0.171597031814934	1.4376156841921	1.29514201034957	1.64753820685619	0.890355287581078	1.11000621762248	0.872584124731976	0.10723214342779	NA	NA	0.830574120996935	0.107960682535294	67.5769734535487
a1500	ARID1A_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	9	24	-1.38629436111989	0.693147180559945	-3.30898521348491	-1.91923060993215	-1.38975460355276	1.10668953797497	1.612421399897	0.927528521016977	1.25577639967189	0.86190533296168	0.107353944561225	NA	NA	0.111018922291395	0.0104218188063045	67.5769734535487
a1501	loss_cnaOV83	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.4696267666107	0.626530623655583	0.843096142955114	0.366928305327781	1.07333757753825	0.836267494243954	2.29771356069673	0.785490194882394	0.107396927948858	NA	NA	0.763111333518706	0.00469531917975404	67.5769734535487
a1502	gain_cnaOV19	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.25989654167847	2.6597744172304	0.60012212444806	0.499920770214635	0.548042651806266	1.10120871237871	1.2004344692268	1.09502813781035	0.10741203570199	NA	NA	0.121258307128818	0.161743539883018	67.5769734535487
a1503	gain_cnaOV49	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	1.13211452244824	2.46508802842222	-1.33297350597398	0.699735150892019	1.55553784508625	0.879859617668266	1.90496862173455	0.856921295862185	0.1075178380574	NA	NA	0.224922639783989	0.0490329353305251	67.5769734535487
a1504	PIK3CA_mut	301	PHA-793887	CDK-pan	6	26	2.32630161961136	NA	2.05223696675054	3.230824705852	-1.17858773910146	1.250862849156	1.62122786786593	0.752804212655594	0.942219796436274	0.726972292089249	0.107521248472962	NA	NA	0.65095664274324	0.0805528793343821	67.5769734535487
a1505	loss_cnaOV1	1248	FK866	NAMPT	3	29	0	NA	0.988130173143435	-1.98730477569047	2.97543494883391	2.20594908184624	2.66010834462694	1.13036844183137	1.348823040985	1.11853900794826	0.107548858233805	NA	NA	0.0372507823178478	0.129618354182815	67.5769734535487
a1506	NF1_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.50586719686211	3.71626974971849	0.789597447143622	0.744113103946819	0.851280942859223	0.943578111452001	1.06112557749024	0.927540377553358	0.107569348794805	NA	NA	0.936335447619574	0.121180455322058	67.5769734535487
a1507	gain_cnaOV49	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	3.34784061759431	4.04522510379395	-0.697384486199637	0.514192056709169	0.752024486775147	0.944254581870918	1.35627238324703	0.927342790645264	0.107679032139404	NA	NA	0.509345014143889	0.124345776885908	67.5769734535487
a1508	loss_cnaOV20	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	5.19028282181632	4.3147667341862	0.875516087630125	0.992054911287716	0.927599704728107	0.934930856528185	0.882527849686949	0.943851192672329	0.107730914710621	NA	NA	0.0256132163367849	0.12253039816851	67.5769734535487
a1509	loss_cnaOV16, loss_cnaOV17	1047	Nutlin-3a	MDM2	6	27	2.07944154167984	1.38629436111989	4.79763066972675	3.51438270297227	1.28324796675448	0.893409504713061	1.57679463921057	0.86242450620971	1.43634913215595	0.813833288650034	0.107855144816256	NA	NA	0.15004668203151	0.0179234719301986	67.5769734535487
a1510	loss_cnaOV58	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	4.12412365113014	2.80349058877794	1.3206330623522	1.09727046104067	1.61876833171326	0.846915316814325	1.20356202890916	0.815825857523712	0.107894096576337	NA	NA	0.65098785757502	0.0540430200997501	67.5769734535487
a1511	loss_cnaOV33_(ZFHX3)	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	2.8391601778184	3.64511731482604	-0.805957137007646	0.453570594382801	0.903486592948886	0.927410048289075	1.7769166409572	0.892052127057122	0.107913345555666	NA	NA	0.650803095316248	0.0246638506138719	67.5769734535487
a1512	loss_cnaOV36	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.73902860929975	3.70394904123738	1.03507956806238	1.09475272536941	0.98413102216355	1.04354301362622	0.945491656769429	1.05177008421787	0.107952977589329	NA	NA	0.706488214073155	0.237955279710086	67.5769734535487
a1513	loss_cnaOV43_(NF1)	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.51755397278947	4.97764358630001	0.539910386489462	0.423531825057144	0.610295322252361	0.916926660064654	1.27478114877581	0.884670694340019	0.107975732360462	NA	NA	0.0976961365092186	0.043663584360334	67.5769734535487
a1514	gain_cnaOV49	293	MP470	PDGFR	3	29	2.99573227355399	NA	2.42941122335833	4.21681150383703	-1.7874002804787	2.99118823456667	1.56549166353998	1.05253054786395	0.597555265771378	1.14175011091208	0.107990152029893	NA	NA	0.608503558564914	0.409767517665829	67.5769734535487
a1515	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	5.29874219719182	4.29292689174603	1.0058153054458	0.332550132291779	0.975474745071583	1.0628907436343	3.02455241414037	1.03110337866511	0.108027548435334	NA	NA	0.49498062720261	0.00706883917579851	67.5769734535487
a1516	loss_cnaOV44	1030	KU-55933	ATM	3	30	2.30258509299405	NA	5.10651157963273	4.0554430612805	1.05106851835223	1.14072542197497	0.979089461802951	1.0613487134272	0.921403606954323	1.07351632241729	0.108092881740625	NA	NA	0.514135851243983	0.247176158727168	67.5769734535487
a1517	MLL2_mut	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	3.36355947007054	3.88915780462451	-0.525598334553972	0.558607123293703	0.87450124324991	0.612843055930807	0.940908757938672	0.601026400603721	0.108128858178126	NA	NA	0.920832135931786	0.237795890707161	67.5769734535487
a1518	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	309	Y-39983	ROCK	3	29	2.99573227355399	NA	6.12116847262826	4.84461247105823	1.27655600157003	0.361997335705036	1.2246744670161	1.07559767601339	3.52642374862725	1.04236353084125	0.108175221839845	NA	NA	0.354186841399948	0.00276012809440341	67.5769734535487
a1519	gain_cnaOV72_(ASXL1)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	1.42814910339875	0.437936828578077	0.990212274820673	0.531721888694807	1.22615620925228	0.843788295716307	1.86227480168496	0.807574326459199	0.108400615180659	NA	NA	0.412440440189419	0.0213217474631376	67.5769734535487
a1520	loss_cnaOV21, loss_cnaOV22	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	3.46513221599065	1.06486810769139	2.40026410829926	3.18640918495648	2.14814644830515	1.07517632596906	0.753281819432126	1.11736521045529	0.108605527306566	NA	NA	0.345078353883038	0.320696849473529	67.5769734535487
a1521	PIK3R1_mut	306	TG101348	JAK2	5	27	2.32630161961136	NA	3.58781357342759	2.682622515432	0.905191057995586	1.63361341939313	1.32109699711524	0.662221668675809	0.554103588553927	0.685181375759819	0.108612157234931	NA	NA	0.613953657360332	0.294504347415947	67.5769734535487
a1522	TP53_mut	254	AC220	FLT3	22	10	0.0237165266173161	NA	2.39002703031956	2.77656282932352	-0.386535799003953	0.707580025243137	0.245041933650064	0.63676825041021	0.54627856244406	1.57742714990142	0.108636689165472	NA	NA	0.852557553987658	0.0302385894095819	67.5769734535487
a1523	loss_cnaOV58	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.70411966137369	0.714647648536605	0.989472012837084	2.21094399540412	0.954516917178922	0.82416176608805	0.447533729888181	1.03662071884642	0.108650082207351	NA	NA	0.838843897995376	0.377469371950096	67.5769734535487
a1524	loss_cnaOV102	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.23748763323501	4.32999181906375	0.907495814171265	0.918912414006362	0.918459004597348	0.988030970621774	0.987575965172434	0.98806349508121	0.108705868912694	NA	NA	0.778238446832305	0.222525708285682	67.5769734535487
a1525	loss_cnaOV20	1248	FK866	NAMPT	5	27	0	NA	0.394234877860874	-2.09772675425547	2.49196163211635	2.2102418354839	2.67607964265033	0.951580722578526	1.12746107331317	0.931198605751644	0.108712804877095	NA	NA	0.0373034504965546	0.0640140752324345	67.5769734535487
a1526	gain_cnaOV48_(SOX17)	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	-0.59585137629752	1.48496985861775	-2.08082123491527	1.82234535607148	2.28944165971801	0.920185764477673	1.14183693446614	0.908877160543837	0.108798336858896	NA	NA	0.345101729279136	0.174148531655339	67.5769734535487
a1527	loss_cnaOV44	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.54417097308376	4.00790633930131	1.53626463378245	0.422226359798591	1.43989175774303	1.10100218410418	3.63848584563805	1.06693063941867	0.108907185066569	NA	NA	0.0818935465449741	0.00226933123183008	67.5769734535487
a1528	loss_cnaOV33_(ZFHX3)	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-1.3608222789923	-2.92809163559313	1.56726935660083	1.85904938078295	1.68257567735565	0.921355643272149	0.843048803760537	0.931470350899144	0.108917113167334	NA	NA	0.684938423824036	0.190812701374847	67.5769734535487
a1529	loss_cnaOV40	1026	17-AAG	HSP90	8	25	0	NA	0.833894787194494	-0.967544780845103	1.8014395680396	2.50219680750636	2.06886942918564	0.828522572482909	0.719943196568489	0.870736230439003	0.10892233670376	NA	NA	0.0525599549157112	0.094153357886586	67.5769734535487
a1530	loss_cnaOV21, loss_cnaOV22	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.21093278062712	3.35873634213045	-1.14780356150333	0.579747332940487	1.06527960880681	1.10367101225484	1.97983413857491	1.0774669410869	0.108968780718879	NA	NA	0.0532822051730332	0.0475917451541942	67.5769734535487
a1531	loss_cnaOV52, loss_cnaOV53	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.49072564465943	3.71945744491905	0.771268199740375	0.884111519529233	0.831829159087672	0.918726087462274	0.872365287301149	0.92719543588287	0.109173649714835	NA	NA	0.936373562660323	0.181096234222426	67.5923613900183
a1532	loss_cnaOV55	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.49072564465943	3.71945744491905	0.771268199740375	0.884111519529233	0.831829159087672	0.918726087462274	0.872365287301149	0.92719543588287	0.109173649714835	NA	NA	0.936373562660323	0.181096234222426	67.5923613900183
a1533	loss_cnaOV42	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	0.234375345069044	-1.53908111220476	1.77345645727381	1.79153244788865	1.78699016841055	0.992174047775297	0.98991031915936	0.992426532962528	0.109207306903246	NA	NA	0.0639948575507016	0.139329002035386	67.5923613900183
a1534	loss_cnaOV54	1047	Nutlin-3a	MDM2	11	22	2.07944154167984	1.38629436111989	4.48354801862147	3.37977676335344	1.10377125526803	1.0283402277438	1.65052697261309	0.746443214536162	1.07335220920972	0.668738695933311	0.10931654279164	NA	NA	0.150188749525597	0.0255302326787479	67.615864550107
a1535	SMAD4_mut	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	9.63780628424651	8.61799304727206	1.01981323697445	0.870407273193833	1.22630714085291	0.853816141540494	1.17165063801959	0.831613225594659	0.109524758961269	NA	NA	0.513403096133987	0.0947348982826213	67.6380014045244
a1536	loss_cnaOV16, loss_cnaOV17	312	AV-951	VEGFR	6	26	-2.05572501506252	NA	1.06411185769333	0.541939877609896	0.522171980083431	0.661362479813989	0.569304769592121	0.891605711165137	0.789539769825307	0.917209916329248	0.10965404898205	NA	NA	0.0118756527015549	0.118204905315743	67.6380014045244
a1537	loss_cnaOV43_(NF1)	1005	Cisplatin	DNA crosslinker	5	26	1.79175946922805	2.30258509299405	3.92026740339479	2.85112624410321	1.06914115929159	1.13539033835561	1.13125623092627	0.944615058929671	0.941650746156627	0.945091951817296	0.109744870782706	NA	NA	0.0769441564879624	0.105004597032015	67.6380014045244
a1538	loss_cnaOV36	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	5.12788896748032	4.10073541184993	1.02715355563039	1.39124024280021	0.890043376774239	1.10223693529188	0.738300635670938	1.15404887271121	0.109836233193428	NA	NA	0.0405225103051103	0.328326607567952	67.6380014045244
a1539	loss_cnaOV55	164	JQ12	HDAC	4	15	1.63315443905142	NA	0.146594998348057	2.2331725398968	-2.08657754154875	0.968234192253497	2.22081118313941	1.01487832815995	2.1550339352222	0.939556481609165	0.109845835835509	NA	NA	0.637351718525946	0.0164320949998641	67.6380014045244
a1540	loss_cnaOV55	295	NVP-BHG712	EPHB4	7	25	2.32630161961136	NA	2.57441059119583	3.44061112501174	-0.866200533815906	1.00314316470598	1.03858915934034	0.839669171300589	0.863486453670639	0.834016536785414	0.10994254647036	NA	NA	0.0533373181664839	0.0731823705574633	67.6380014045244
a1541	loss_cnaOV1	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	5.29398694633446	4.29341881424851	1.00056813208594	0.875444207721755	0.951698181834923	1.05678299863058	1.14292621192824	1.05135026123177	0.110064986134765	NA	NA	0.495202361939661	0.175883536000261	67.6380014045244
a1542	loss_cnaOV41	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	3.08137830414122	1.52232768840338	1.55905061573784	1.40116819523427	1.53233865290919	1.02616744795625	1.11267913519631	1.01743215364171	0.110224694825649	NA	NA	0.0341871060832801	0.107154419608883	67.6380014045244
a1543	loss_cnaOV42	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	3.08137830414122	1.52232768840338	1.55905061573784	1.40116819523427	1.53233865290919	1.02616744795625	1.11267913519631	1.01743215364171	0.110224694825649	NA	NA	0.0341871060832801	0.107154419608883	67.6380014045244
a1544	loss_cnaOV36	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	4.75891189552904	5.6194182715208	-0.860506375991759	2.57059187869981	0.70931825314355	0.901996448128651	0.334750289659748	1.21314568203789	0.110288726231843	NA	NA	0.286005295412176	0.621134080500536	67.6380014045244
a1545	PTEN_mut	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	1.68321973275541	-0.0496201475874948	1.7328398803429	1.69858080819635	1.53722502994634	1.11876039580625	1.02016923303339	1.12725192901874	0.110347710490378	NA	NA	0.444093556789614	0.212683100432993	67.6380014045244
a1546	loss_cnaOV85	288	KIN001-055	JAK3, MNK1	7	25	2.32630161961136	NA	4.37046826744599	3.64153320606645	0.728935061379541	0.9740728924855	0.99644133374822	0.734807646612498	0.748337282561625	0.731538362261203	0.11039407181912	NA	NA	0.706661322838738	0.112823437401316	67.6380014045244
a1547	gain_cnaOV18_(CCNE1)	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	3.18278639708119	2.64935721915687	0.533429177924321	0.436345904752082	0.555167786476625	0.979751077542543	1.22249154195087	0.960843173754247	0.110478540855085	NA	NA	0.121537227941564	0.0844860472078138	67.6380014045244
a1548	loss_cnaOV57_(ZNRF3)	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	3.46918706203579	2.22875869197657	1.24042837005923	1.71206646578461	1.18954274234805	0.992585055179663	0.724521153149717	1.04277746893797	0.110569846514502	NA	NA	0.0977978952136378	0.24474843939286	67.6380014045244
a1549	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1143	HG-5-88-01	EGFR, ADCK4	6	16	2.30258509299405	NA	3.19046580542544	3.78532755739808	-0.594861751972637	1.10453978739405	0.781014625530448	0.68123819978497	0.538560727971692	0.761652512676854	0.11082407952314	NA	NA	0.0470981664681025	0.265506585939051	67.6380014045244
a1550	gain_cnaOV72_(ASXL1)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.45242950499935	1.25444651697967	1.19798298801968	1.51734333946327	1.40823741907258	0.843701640790682	0.789526639661821	0.85069674459342	0.110849426234456	NA	NA	0.458972629021065	0.214704421608697	67.6380014045244
a1551	loss_cnaOV41	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.7040601729301	2.46779736780505	1.23626280512506	1.40981663029301	1.6881430718878	0.747048677814491	0.876896171148245	0.732321108152631	0.110881127334139	NA	NA	0.627554100325882	0.128787958808957	67.6380014045244
a1552	loss_cnaOV34	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.94360348322487	4.10177463825061	0.841828844974265	1.17229178744945	0.895526966692269	0.899534758782385	0.718105214066058	0.940037403992038	0.110918076344427	NA	NA	0.19339112664629	0.188572585315607	67.6380014045244
a1553	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	4.29448132728176	3.40052009357358	0.893961233708179	1.27968717951247	0.837819425125153	1.02389140931671	0.698577939999956	1.06700943771343	0.111093217679046	NA	NA	0.78667466610401	0.349369898512535	67.6380014045244
a1554	loss_cnaOV43_(NF1)	1021	Axitinib	PDGFR, KIT, VEGFR	5	25	0.693147180559945	NA	3.28612693452481	2.37311008498269	0.913016849542115	0.975667256014921	0.988566908848706	0.925291370562004	0.935787117906673	0.923576180195454	0.111098151214769	NA	NA	0.178168820962801	0.107228260467476	67.6380014045244
a1555	loss_cnaOV85	1008	Methotrexate	Dihydrofolate reductase (DHFR)	7	24	-1.6094379124341	NA	1.26720754164045	0.361101583071664	0.906105958568783	0.776210555107732	1.23868210297751	0.78230668047832	1.16734557731313	0.731508073290727	0.11115833952754	NA	NA	0.412773629754064	0.0326652107765637	67.6380014045244
a1556	gain_cnaOV26	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	2.33601956577803	0.866401008508073	1.46961855726996	1.42898576425497	1.50290176285906	0.980996477205083	1.02843470805056	0.977854037827607	0.11128997430772	NA	NA	0.783092492388213	0.208791900767902	67.6380014045244
a1557	gain_cnaOV48_(SOX17)	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	5.33622931855782	6.00832175129915	-0.672092432741324	0.794177517541429	0.671031373998985	0.988880272577667	0.846274816267716	1.00158123566714	0.111381668810469	NA	NA	0.905290614849657	0.277239677264429	67.6380014045244
a1558	loss_cnaOV42	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	5.03474595779739	3.57017700577318	1.46456895202421	0.987881969527798	1.53821025737227	0.980405653502956	1.48253434843463	0.952125332024594	0.111482800976317	NA	NA	0.150395644279643	0.0477608507653799	67.6380014045244
a1559	loss_cnaOV84	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	2.29220853773887	1.36061990430551	0.931588633433361	1.47208192579056	0.862280300970916	0.924829810228045	0.63283749165867	1.08037796106951	0.111566187484518	NA	NA	0.429083989897887	0.236688123724296	67.6380014045244
a1560	loss_cnaOV85	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	2.29220853773887	1.36061990430551	0.931588633433361	1.47208192579056	0.862280300970916	0.924829810228045	0.63283749165867	1.08037796106951	0.111566187484518	NA	NA	0.429083989897887	0.236688123724296	67.6380014045244
a1561	loss_cnaOV41	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	4.04037722122002	3.13467491595731	0.90570230526271	1.03063644919214	0.987556039503414	0.911712273752319	0.878779618140458	0.9171148461794	0.111724958823197	NA	NA	0.0805818330610334	0.124113257289233	67.6380014045244
a1562	loss_cnaOV43_(NF1)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.58144260346876	5.06114218706199	0.520300416406773	0.630549319288595	0.54658384078337	0.931588142872697	0.825154195700015	0.951913279509091	0.111776257961844	NA	NA	0.00925683224254733	0.142438306712759	67.6380014045244
a1563	loss_cnaOV57_(ZNRF3)	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.54313961210915	4.85414904032945	0.6889905717797	0.696580718325262	0.801830478553319	0.869656116494673	0.989103708520943	0.859272115750441	0.111813863559397	NA	NA	0.943960530683168	0.139928469076604	67.6380014045244
a1564	loss_cnaOV85	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	4.41316764085557	3.85851505507274	0.554652585782833	0.702630138533803	0.737157909647947	0.759399693043198	0.789394811529493	0.752420313915813	0.111928180437648	NA	NA	0.509795761496613	0.0977193973429725	67.6380014045244
a1565	PIK3R1_mut	304	SB52334	ALK5	5	27	2.99573227355399	NA	5.16065256017683	4.21960120158878	0.941051358588046	0.551556330836413	1.06466186396327	0.930442993791743	1.70617452103393	0.883896935206191	0.11194485812336	NA	NA	0.33377977279173	0.0140187559873061	67.6380014045244
a1566	gain_cnaOV95_(MECOM)	346	THZ-2-102-1	CDK7	9	23	0.916290731874155	2.99573227355399	-1.9582210773501	-0.707712752345514	-1.25050832500458	0.779606394987936	2.17184930756116	0.657147496412407	1.60402522740201	0.575780428527437	0.112001386026617	NA	NA	0.426340804003912	0.023078614104817	67.6380014045244
a1567	loss_cnaOV43_(NF1)	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	5.00982355239535	3.39378996109275	1.6160335913026	0.649608264625556	2.08129518068657	0.827866601342844	2.48770478964597	0.776455740780369	0.112050989346712	NA	NA	0.738008258285878	0.00359066621275609	67.6380014045244
a1568	loss_cnaOV41	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	4.69259687047594	3.31763091237972	1.37496595809622	0.745337394380184	1.74340462739419	0.837266430161917	1.84475643978607	0.788667149605617	0.11218361694758	NA	NA	0.68711226243169	0.0119058573646626	67.6380014045244
a1569	loss_cnaOV43_(NF1)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	6.01059594795611	4.84821934794871	1.1623766000074	0.584122197342838	1.1676998348485	1.04247996345604	1.98995450831184	0.995441264371001	0.112255846149875	NA	NA	0.786753701406262	0.0423437000281307	67.6380014045244
a1570	loss_cnaOV44	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.33021569172097	5.75488628434644	-0.424670592625465	0.36266035066535	0.471087115246689	0.913964906817602	1.1709871008682	0.901469343739284	0.112359521874794	NA	NA	0.363872172424461	0.166219276031329	67.6380014045244
a1571	loss_cnaOV34	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.01175053595863	3.07079930047181	-1.05904876451318	0.523772885765675	1.26564583808522	0.887218088875238	2.02196179545457	0.836765493667171	0.112469109781052	NA	NA	0.214538075494786	0.00697346632296754	67.6380014045244
a1572	loss_cnaOV58	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-3.22233441360162	-4.36142806878534	1.13909365518372	2.43816298042622	0.989490066294433	0.889167304450434	0.467193401068123	1.15119261323112	0.112478491120381	NA	NA	0.200964207262768	0.358430970236095	67.6380014045244
a1573	loss_cnaOV102	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	1.01556532163912	-0.232045866214785	1.2476111878539	0.580509789387957	1.24588023617148	1.02956971679022	2.14916476976088	1.00138934034923	0.112656685533975	NA	NA	0.75813273137414	0.0338877050508136	67.6380014045244
a1574	loss_cnaOV33_(ZFHX3)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	2.12567184739458	0.843964305517497	1.28170754187708	1.08188917320842	1.53886346345333	0.854787245009135	1.18469393503226	0.832892308067945	0.112704124423094	NA	NA	0.783166256027189	0.0919472274743992	67.6380014045244
a1575	gain_cnaOV18_(CCNE1)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	2.81807145908373	1.58878390257094	1.22928755651279	1.21689470055524	1.70500769853222	0.738736652160892	1.0101840002688	0.720986513768262	0.112799504088796	NA	NA	0.21284452970644	0.135428280475538	67.6380014045244
a1576	gain_cnaOV94	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-1.720754966305	-1.02647002238256	-0.694284943922434	0.801140529658266	1.40393803551213	0.529717245597883	0.866620671679896	0.494526771382167	0.112834647644636	NA	NA	0.0387677623047252	0.180636594005962	67.6380014045244
a1577	loss_cnaOV84	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	2.96907878936849	3.81544951788702	-0.846370728518536	0.919239324054348	0.815713750503418	1.01066030581874	0.920729462253179	1.03758300996667	0.112849491896801	NA	NA	0.0472517854277485	0.113084445458565	67.6380014045244
a1578	loss_cnaOV85	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	2.96907878936849	3.81544951788702	-0.846370728518536	0.919239324054348	0.815713750503418	1.01066030581874	0.920729462253179	1.03758300996667	0.112849491896801	NA	NA	0.0472517854277485	0.113084445458565	67.6380014045244
a1579	gain_cnaOV96	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	1.21999537990455	0.15162458390075	1.0683707960038	1.46279647427379	1.04245716203995	0.979939945948488	0.730361888884232	1.02485822430644	0.112903753097937	NA	NA	0.132892418536512	0.241814111246361	67.6380014045244
a1580	PIK3R1_mut	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	3.25123818805486	2.140401676568	1.11083651148686	0.676680570670405	1.47511489705473	0.796122003179662	1.64159658136235	0.753050839432779	0.112911836300723	NA	NA	0.814187817275949	0.019399011023467	67.6380014045244
a1581	PIK3CA_mut	312	AV-951	VEGFR	6	26	-2.05572501506252	NA	0.0700328338002674	0.771342729277525	-0.701309895477257	0.645481257001761	0.534340937431245	1.26495775212157	1.08649149432288	1.31247644780632	0.112915489991839	NA	NA	0.0119374728803907	0.0442827504448043	67.6380014045244
a1582	loss_cnaOV58	326	GSK690693	AKT	5	27	2.32630161961136	NA	5.21865341165797	3.9543899889148	1.26426342274317	0.581528774482692	1.47712527102107	0.908609190962103	2.17403416343038	0.855894518593704	0.112939211828094	NA	NA	0.0821857613768619	0.00476578421611048	67.6380014045244
a1583	loss_cnaOV102	293	MP470	PDGFR	3	29	2.99573227355399	NA	5.52904293345058	3.89615994762059	1.63288298582999	1.07123037426805	1.74905669841563	0.953654858386458	1.52430609237131	0.933579218620602	0.112971373126308	NA	NA	0.608949082689595	0.0950386915312617	67.6380014045244
a1584	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	3.46589059951463	2.14355469365851	1.32233590585612	1.83006951111267	1.42960193267221	0.889057090438036	0.722560480804987	0.92496790584524	0.113078605659633	NA	NA	0.225533409321115	0.18659822655668	67.6380014045244
a1585	loss_cnaOV83	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	6.16100152168444	5.64600636163884	0.514995160045606	0.625045659783719	0.570392068431412	0.891029171991036	0.823932063177284	0.902879244905791	0.113285342460637	NA	NA	0.176333328873364	0.143605572758913	67.6380014045244
a1586	loss_cnaOV42	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.76551618833227	3.78193610405456	0.983580084277708	0.733272336342173	1.05855094332089	0.953483512559486	1.34135714049184	0.929175955568106	0.113331768969792	NA	NA	0.299135552947234	0.0651410847085169	67.6380014045244
a1587	loss_cnaOV43_(NF1)	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.02845848248752	-3.72426211939933	1.69580363691182	1.89577336021977	1.63650357478237	1.0160003174953	0.894518127797316	1.03623582804415	0.113351177345263	NA	NA	0.660033178296912	0.256085644650573	67.6380014045244
a1588	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	5.09465247825015	4.19345277540857	0.901199702841581	1.40463302942219	0.808897087012278	1.04605091406669	0.641590852531993	1.11410922021024	0.113394305999871	NA	NA	0.505830959791316	0.3821998206821	67.6380014045244
a1589	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	292	Masitinib	KIT	7	25	2.99573227355399	NA	4.53381787988777	3.86783713171626	0.665980748171509	0.731517982769416	1.08004039966322	0.65298082331022	0.910409263829998	0.61662577472026	0.113483733974394	NA	NA	0.0926153079093858	0.0781475452540693	67.6380014045244
a1590	gain_cnaOV95_(MECOM)	1022	AZD7762	CHEK1, CHEK2	8	23	0.693147180559945	NA	-0.418695823408057	-0.953431341591713	0.534735518183656	0.863162515346556	0.746994783883772	0.688535088061882	0.619507344997439	0.715849065777222	0.113602497231567	NA	NA	0.0681887327204056	0.147173164661241	67.6380014045244
a1591	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.34617353651821	2.20642437974545	1.13974915677277	1.53240970851445	1.20059143425444	0.912988020895496	0.743762683334645	0.949323078821182	0.113612202444904	NA	NA	0.0980304801995196	0.176197192299596	67.6380014045244
a1592	gain_cnaOV19	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	3.80466485855817	2.19783299481123	1.60683186374694	1.31744384265997	1.50268131506474	1.07738030531782	1.21965871463841	1.0693098048389	0.113770139096895	NA	NA	0.225607074154744	0.156991564323819	67.6380014045244
a1593	NF1_mut	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.64243188730471	3.92367592510364	0.718755962201067	1.40993956735492	0.978661938660123	0.697856111107425	0.509777850656018	0.734427215167997	0.113771938425536	NA	NA	0.0926370731779849	0.388477556454324	67.6380014045244
a1594	loss_cnaOV82	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.45198077687477	2.16973816553063	1.28224261134414	1.42983965807236	1.36333534483607	0.937294277944682	0.896773707530814	0.940518865150023	0.113805904002785	NA	NA	0.513862754994871	0.255823814724201	67.6380014045244
a1595	loss_cnaOV59	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.110735702165102	1.47159368920728	-1.36085798704218	1.29335062664017	1.29881742024471	1.04807060268745	1.05219571476713	1.04776696541826	0.113819101693047	NA	NA	0.566030259551013	0.2018108875265	67.6380014045244
a1596	loss_cnaOV42	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.69389412927065	3.55717498691749	1.13671914235316	1.07423706159058	1.18348798855198	0.96877272477036	1.05816414550999	0.960482196142907	0.113984237023287	NA	NA	0.182579610488146	0.120406270520799	67.6380014045244
a1597	loss_cnaOV43_(NF1)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-2.54172814614222	-4.25259667715963	1.71086853101741	1.52880087748792	1.74461245400994	0.994327750459853	1.11909180339343	0.980658212707945	0.113991137153472	NA	NA	0.564431676802809	0.178510167656446	67.6380014045244
a1598	gain_cnaOV48_(SOX17)	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	2.10213303873766	3.69339246278713	-1.59125942404947	1.85717050763512	1.6372660364065	0.96243329548977	0.856819240617677	0.971900344028386	0.114037344335847	NA	NA	0.687250922168608	0.272473183136888	67.6380014045244
a1599	loss_cnaOV43_(NF1)	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.667908156502112	-0.162638488872353	0.830546645374465	1.08196948378212	0.953223571114145	0.856888986820796	0.76762483399367	0.87130309251974	0.114106541627891	NA	NA	0.16242751826695	0.313848050372527	67.6380014045244
a1600	loss_cnaOV42	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.58314140025259	4.63378259980264	0.949358800449951	0.432944395940805	1.25231723472665	0.795159434479693	2.19279614045346	0.758081717734385	0.114126614221185	NA	NA	0.406998475250908	0.0118820559705785	67.6380014045244
a1601	BRCA1_mut	1025	SB 216763	GSK3A, GSK3B	4	19	2.30258509299405	NA	5.49890328122289	4.84649350754705	0.652409773675836	0.281905697743721	0.849694867009597	0.821832432495025	2.31428374416518	0.767816540980078	0.114128476973342	NA	NA	0.429475486300615	0.0155068608421346	67.6380014045244
a1602	loss_cnaOV87, loss_cnaOV88	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.90306895845328	3.80096682985172	1.10210212860156	0.832470955324739	1.0453497914022	1.06695611379243	1.32389258934763	1.05429028413851	0.11429024943074	NA	NA	0.299242194532971	0.133751932303657	67.6894047497063
a1603	loss_cnaOV84	293	MP470	PDGFR	6	26	2.99573227355399	NA	5.00700175401106	3.82822141374164	1.17878034026943	1.15342548929305	1.80859940574634	0.686592778523805	1.02198221836759	0.651764197491257	0.114357891864407	NA	NA	0.609069185005925	0.0696511907059615	67.6894047497063
a1604	TP53_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	21	10	-1.6094379124341	NA	0.787654889730964	0.0996138100852832	0.688041079645681	1.14033872697766	1.25342956734762	0.584770737660777	0.603365529353948	0.548926798576841	0.114515657453817	NA	NA	0.41316710091425	0.160503019055919	67.6947647689656
a1605	PIK3R1_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	0.219004279237083	1.5853243282037	-1.36632004896662	0.600612840758513	1.46605646421553	0.974875231868666	2.27487651985778	0.931969594839396	0.114668058572662	NA	NA	0.459404075813545	0.00806371794921646	67.6947647689656
a1606	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1375	Temozolomide	DNA akylating agent	8	25	3.40119738166216	NA	6.29302318380537	5.8365662009682	0.456456982837171	0.584363937183833	0.70410888319167	0.672329759508804	0.781117645686571	0.648276131339357	0.114682647707171	NA	NA	0.905364082088996	0.0891229643897221	67.6947647689656
a1607	loss_cnaOV70	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	2.32380052994382	0.86766504669782	1.456135483246	1.23065382874834	1.51664828373276	0.971223041986171	1.18322102384144	0.960100966627655	0.114688207643898	NA	NA	0.783268008139369	0.1639903917273	67.6947647689656
a1608	gain_cnaOV18_(CCNE1)	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	3.87208576736456	3.16242175693593	0.709664010428633	1.25035983282877	1.04661956234276	0.664017566261268	0.567567824714196	0.678053455106569	0.114882367001359	NA	NA	0.0536094014603252	0.345788745591847	67.6947647689656
a1609	SMAD4_mut	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-3.12318834279653	-4.94114248284497	1.81795414004845	3.55406977499149	1.64277952648655	0.924443424659502	0.511513350930989	1.10663306349851	0.114956267476381	NA	NA	0.317625759412423	0.470566967974523	67.6947647689656
a1610	gain_cnaOV49	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	1.65065921997822	3.15044436181795	-1.49978514183973	1.49810607362416	1.57775175920381	0.953717469032575	1.00112079394452	0.950583723384075	0.115008693170754	NA	NA	0.65156133537346	0.217562472531601	67.6947647689656
a1611	loss_cnaOV83	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	4.07345913635943	3.11850999618724	0.954949140172194	0.824013680863764	0.917572020134116	1.05897509035074	1.1588996182335	1.0407348079692	0.115165760137074	NA	NA	0.162027226291415	0.0986512977925156	67.6947647689656
a1612	loss_cnaOV20	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	3.07273478767408	2.27815816508784	0.79457662258624	0.902629819113849	0.764861422269329	1.00462428581994	0.880290685905226	1.03885043676114	0.11518706409034	NA	NA	0.597637326805006	0.178255989090238	67.6947647689656
a1613	BRCA1_mut	1262	UNC1215	LMBL3	4	29	0	NA	3.09448937551032	2.73709178440562	0.357397591104698	0.532596072991539	0.478575856422908	0.738322321926596	0.671048115501925	0.746794027128842	0.115420859965857	NA	NA	0.0978559400035728	0.277085466495525	67.6947647689656
a1614	loss_cnaOV102	152	CP466722	ATM	3	29	2.77258872223978	NA	3.38303884452853	2.57076611678751	0.812272727741024	0.167095724673152	0.809588784943075	1.03695346573526	4.86112214618219	1.0033151926606	0.115424228229236	NA	NA	0.541168523115301	0.000304569098339738	67.6947647689656
a1615	gain_cnaOV96	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	3.77701701037805	3.15374323006571	0.623273780312344	0.593127058243698	1.12631051665197	0.582133235302745	1.05082675229471	0.553376507719259	0.115466073066915	NA	NA	0.0536407543295464	0.0976754486239803	67.6947647689656
a1616	loss_cnaOV82	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	2.32082330805037	0.867973035169555	1.45285027288082	1.23580812389377	1.51665483414147	0.96884522529676	1.1756277085339	0.957930730299111	0.115527792505693	NA	NA	0.783310469261133	0.165907898901731	67.6947647689656
a1617	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1030	KU-55933	ATM	3	30	2.30258509299405	NA	5.08848109568341	4.05724610967543	1.03123498600797	1.16898506131666	0.978774052004643	1.03939759343935	0.882162672674758	1.05359861542701	0.115608645537334	NA	NA	0.514886129792459	0.262458194606081	67.6947647689656
a1618	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.88386154640305	3.54481461666416	1.33904692973889	0.921660929165596	1.56007409185574	0.896813600240663	1.4528628559216	0.858322650654405	0.115634674076605	NA	NA	0.150780405337197	0.0273163226469656	67.6947647689656
a1619	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	4.03361390628527	3.13592738168596	0.897686524599303	1.03968882960583	0.987283747600285	0.902714038766703	0.863418456596902	0.909248761342665	0.115695666212522	NA	NA	0.080859259217302	0.129356822556636	67.6947647689656
a1620	loss_cnaOV36	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.15938387660308	1.36260457022112	1.79677930638196	2.29910309461132	1.82188208323793	0.967302661270389	0.781513152060593	0.986221513956951	0.115707227575937	NA	NA	0.774621686068417	0.306646693906657	67.6947647689656
a1621	loss_cnaOV40	1049	PD-173074	FGFR1, FGFR3	8	25	0.693147180559945	NA	3.56903504357652	2.80010187682008	0.768933166756434	0.808332316364168	0.994542251463782	0.804599838071745	0.95125872266873	0.773152840540165	0.115718549964723	NA	NA	0.0772769644174465	0.0438562478800051	67.6947647689656
a1622	gain_cnaOV96	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.94245425021402	0.692342379413226	1.25011187080079	2.07223164160944	1.17517632676301	0.969413191022136	0.603268401900218	1.06376536212586	0.115999136885364	NA	NA	0.14901388632323	0.316417732732436	67.6947647689656
a1623	loss_cnaOV54	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	2.97357027282712	3.81412849334037	-0.840558220513252	0.823807281143887	0.842224614681513	1.00236677208907	1.02033356557144	0.998021437346745	0.116280893760833	NA	NA	0.0475059711744843	0.088169907228231	67.6947647689656
a1624	loss_cnaOV57_(ZNRF3)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-3.12025495885456	-1.98610286896914	-1.13415208988543	1.67835437282359	1.19110328314049	0.909790475597146	0.675752456245209	0.952186183968103	0.116613070985958	NA	NA	0.594654713426641	0.271985733604805	67.6947647689656
a1625	loss_cnaOV57_(ZNRF3)	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	4.32123466190612	4.86276156086827	-0.541526898962147	0.933339784902576	0.602943932070103	0.841323067905238	0.580203381149848	0.898138069161603	0.116640991351727	NA	NA	0.753466619503029	0.333489394446327	67.6947647689656
a1626	loss_cnaOV36	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.89732776750509	3.80154094894654	1.09578681855855	0.838025491523304	1.04566802999364	1.06023565120789	1.30758172590514	1.04792992338612	0.116663485421743	NA	NA	0.299502065227913	0.137004652007633	67.6947647689656
a1627	loss_cnaOV85	1019	Bosutinib	SRC, ABL, TEC	7	24	0.693147180559945	NA	2.74002802720079	1.4270068588771	1.31302116832369	1.12882791561866	1.59372190326399	0.869935657560198	1.16317212761706	0.823870943628612	0.116733381557476	NA	NA	0.034459873392675	0.028425817950472	67.6947647689656
a1628	gain_cnaOV96	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	0.162913525652217	1.58587317748112	-1.4229596518289	1.67564600437117	1.32092660961304	1.03599057777002	0.849200635526178	1.0772435360703	0.116771884806052	NA	NA	0.845084359177961	0.275232478282929	67.6947647689656
a1629	gain_cnaOV26	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	5.08768663796804	4.19417337957569	0.893513258392355	0.878449060088027	0.861082237868295	1.03625667384571	1.01714863045424	1.03766309313771	0.116811338192287	NA	NA	0.506176666734621	0.213042983541192	67.6947647689656
a1630	loss_cnaOV87, loss_cnaOV88	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	3.79351070384264	2.19894841028278	1.59456229355986	2.77786982287419	1.35987834766963	1.06832402267545	0.574023404707282	1.17257716198835	0.116977986463117	NA	NA	0.225942524039021	0.425304873451356	67.6947647689656
a1631	loss_cnaOV1	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.73588386473615	4.65132300719547	1.08456085754068	0.510757447706425	1.22880502572822	0.908922229922293	2.12343620716829	0.882614275521817	0.117075585894794	NA	NA	0.407336222608306	0.0333896092269538	67.6947647689656
a1632	loss_cnaOV54	300	CX-5461	RNA Pol I	10	21	2.32630161961136	NA	4.26510951097191	3.19382347450159	1.07128603647032	1.54118035399695	1.68797330860086	0.651705079524562	0.695107508794807	0.634658161365297	0.117120680247228	NA	NA	0.687476026121558	0.0953047206088337	67.6947647689656
a1633	NF1_mut	333	T0901317	LXR	4	28	2.32630161961136	NA	3.8341709662138	4.88466329215142	-1.05049232593762	2.45212854280523	0.777592393615071	0.98152063962895	0.428400186858009	1.35095499205416	0.117155508768083	NA	NA	0.00384162338278875	0.455836316771802	67.6947647689656
a1634	loss_cnaOV56	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	4.1647070410667	2.68524184198908	1.47946519907762	1.32475879933424	1.52243482913886	0.979478324869163	1.11678080554825	0.971775717923149	0.117234859022226	NA	NA	0.967686700583501	0.182231219886509	67.6947647689656
a1635	SMAD4_mut	262	VX-11e	ERK	3	29	1.63315443905142	NA	1.83679631532516	2.96505151198444	-1.12825519665928	0.770169997450042	1.09595825304977	1.047290702143	1.46494306503087	1.02946913673002	0.117306532717885	NA	NA	0.373549934038902	0.106812020011	67.6947647689656
a1636	loss_cnaOV58	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	2.51037848127385	1.22603867183374	1.28433980944011	2.25726616382796	1.63989798568669	0.738916843779041	0.568980224849547	0.783182747128203	0.117318814048306	NA	NA	0.601063001568338	0.281196156668949	67.6947647689656
a1637	loss_cnaOV85	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	7	25	0.246860077931526	2.32630161961136	0.172932274616767	1.23692648087003	-1.06399420625327	0.711250375263661	1.63265552696167	0.711924549909411	1.49594888559299	0.651695467097909	0.117341824078596	NA	NA	0.783401034150763	0.0190433165949647	67.6947647689656
a1638	loss_cnaOV102	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.15477317537248	4.42322348230842	0.731549693064056	0.917215033255519	0.651327049795906	1.08915866495277	0.79757708556905	1.12316798955807	0.117540874847862	NA	NA	0.0715809856111777	0.299382696884123	67.6947647689656
a1639	SMAD4_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-3.04215020692554	-1.99687593820073	-1.04527426872481	1.84129767235124	1.17541390793509	0.832631285363103	0.567683479113971	0.889281862047296	0.117560870187522	NA	NA	0.594733694441123	0.342323017955409	67.6947647689656
a1640	gain_cnaOV50	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.59635559784041	3.74217636192893	0.85417923591148	0.738346590622648	0.851370662909867	1.01535586824266	1.15688112704787	1.00329888393384	0.117641560858736	NA	NA	0.936564691793677	0.16903994804676	67.6947647689656
a1641	loss_cnaOV35	158	PF-562271	FAK	3	15	0.940007258491471	NA	3.40523235477349	2.06628132862776	1.33895102614573	1.66770693966393	1.25195938496527	1.0211980500373	0.802869493614716	1.06948439560032	0.117780391750295	NA	NA	0.728826356776485	0.296257699676395	67.6947647689656
a1642	loss_cnaOV56	255	CP724714	ERBB2	3	29	2.32630161961136	NA	5.21747931922189	4.33206164465131	0.885417674570576	0.835923287048683	0.92618184155125	0.961950449228125	1.05920924597835	0.95598686440192	0.117789638080605	NA	NA	0.778716257069964	0.198824457375097	67.6947647689656
a1643	loss_cnaOV41	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.53302008259193	2.04072145316681	0.492298629425127	0.459124835904674	0.543527307092637	0.922965893902739	1.07225440866227	0.905747738891841	0.117839551799895	NA	NA	0.0358875730597053	0.0742635888368854	67.6947647689656
a1644	SMARCA4_mut	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-3.53962773523089	-1.86754332903327	-1.67208440619762	2.14544327134921	1.42794331082854	1.12328172289888	0.779365471241796	1.1709739409945	0.117843668094731	NA	NA	0.0315181324706741	0.307982272457891	67.6947647689656
a1645	loss_cnaOV43_(NF1)	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	5.20462661127653	3.71871150235763	1.48591510891891	1.4257557480548	1.47023993161156	1.01422349157909	1.04219471739545	1.01066164574252	0.117894163998013	NA	NA	0.725969971690524	0.202213020256564	67.6947647689656
a1646	loss_cnaOV58	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	5.00630681559652	4.39748178276384	0.608825032832682	0.665684989146233	0.669427944653543	0.910125612075341	0.914584289505347	0.909470597537983	0.118108125238609	NA	NA	0.0716153711786092	0.112792041900998	67.6947647689656
a1647	loss_cnaOV21, loss_cnaOV22	1061	SB590885	BRAF	3	30	1.6094379124341	NA	2.77147814126308	4.04314599255553	-1.27166785129245	1.95078575094886	1.17270644148606	1.02739931675103	0.651874687250466	1.08438719726054	0.118205820687388	NA	NA	0.559541880471706	0.376046946481386	67.6947647689656
a1648	loss_cnaOV21, loss_cnaOV22	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	1.94526355253083	3.82226400185822	-1.87700044932739	4.90508622300988	1.55418534821457	0.955559863848816	0.382664109047123	1.20770695173756	0.118333703985381	NA	NA	0.738387054792655	0.576211084779866	67.6947647689656
a1649	gain_cnaOV18_(CCNE1)	309	Y-39983	ROCK	4	28	2.99573227355399	NA	5.93286731907856	4.82592135008068	1.10694596899788	0.634881182383327	1.23513145789746	0.931126982701524	1.74354824132988	0.896217128889434	0.118356622517552	NA	NA	0.355365199573177	0.0265737191674903	67.6947647689656
a1650	loss_cnaOV36	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.30033965458339	5.71684613149407	0.583493523089317	0.660039965548317	0.53081137704497	1.07911242519158	0.884027564307548	1.09924833626896	0.118398045224329	NA	NA	0.0981889579705976	0.261745880540742	67.6947647689656
a1651	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.97147617905843	1.51451368472851	0.456962494329919	1.09349764089279	0.497460566179385	0.691161766316146	0.417890699752065	0.918590387655245	0.118419688219742	NA	NA	0.193116183826436	0.319533065730008	67.6947647689656
a1652	gain_cnaOV51_(MYC)	302	PI-103	PI3Ka, PRKDC (DNAPK)	8	24	2.32630161961136	NA	0.35043306664796	1.60304613490994	-1.25261306826198	1.43190203529178	2.47956992503129	0.549725708767222	0.874789641601935	0.505173520462898	0.118486496652527	NA	NA	0.346220874755881	0.0944437049997082	67.6947647689656
a1653	loss_cnaOV58	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-2.99835641218917	-1.96736503480634	-1.03099137738283	1.47883444948301	1.20859971700627	0.826933618236388	0.697164836634187	0.853046184667839	0.118527209320228	NA	NA	0.594813487081451	0.200604243626834	67.6947647689656
a1654	SMAD4_mut	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.87174043643051	4.14071536349722	0.731025072933288	1.17810854334455	0.928024368430843	0.765397342485053	0.620507403212587	0.787721850633456	0.118636639527281	NA	NA	0.194168125460584	0.307448616480544	67.6947647689656
a1655	loss_cnaOV56	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.47478441757817	4.43631822035013	1.03846619722805	0.895446491221846	0.982301264708998	1.06318388642062	1.15971887478284	1.05717689118082	0.118702069556191	NA	NA	0.175905158056781	0.17151217192814	67.6947647689656
a1656	RB1_mut	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	-1.1066393441912	0.513924598414463	-1.62056394260567	3.03936744653434	1.45569923904643	1.00310299427001	0.533191188993461	1.11325464707066	0.118938676213503	NA	NA	0.831068219243445	0.453937625421368	67.6947647689656
a1657	loss_cnaOV43_(NF1)	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.9282215114533	5.12190844530148	0.80631306615182	0.686363807957465	0.688950426069775	1.17083751595837	1.17476046493668	1.17034990565513	0.118974236221352	NA	NA	0.105260248022332	0.165311540363038	67.6947647689656
a1658	loss_cnaOV38	1023	GW 441756	NTRK1	8	23	0.693147180559945	NA	1.69511063984492	2.50833228822193	-0.813221648377008	1.26666691575586	1.19509546183785	0.67055552000658	0.642016964571726	0.680465849252255	0.11901855856257	NA	NA	0.838644510061787	0.139314317181024	67.6947647689656
a1659	loss_cnaOV102	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-0.537953359621941	-2.18915129784851	1.65119793822657	0.7597166675868	1.53107556759623	1.10763070454445	2.17343913681861	1.07845619979354	0.119026710508076	NA	NA	0.0315627022688592	0.0340352890879557	67.6947647689656
a1660	loss_cnaOV41	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	5.00519208764055	4.3976808413274	0.607511246313144	0.654420860810392	0.67125837219021	0.907939816400828	0.928318888797099	0.905033399182688	0.119112935243648	NA	NA	0.0716758586895371	0.108829979262805	67.6947647689656
a1661	loss_cnaOV70	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	4.5341119645492	2.66932911572597	1.86478284882323	1.09219037406023	1.82124921382865	1.04648466389622	1.70737894520246	1.02390317297821	0.119130213815052	NA	NA	0.329093347811751	0.0725877156979077	67.6947647689656
a1662	loss_cnaOV102	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	5.43324158886706	3.46143868775447	1.97180290111258	0.332790621578972	2.02255155868225	1.00815194990901	5.92505549512509	0.974908596346129	0.119145623209432	NA	NA	0.738434345798058	0.000107552753965019	67.6947647689656
a1663	gain_cnaOV19	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	5.05207452521583	4.46072864133247	0.591345883883355	0.347637363821906	0.59026767837041	1.0243768765326	1.70104236605102	1.00182663823966	0.119167705162355	NA	NA	0.602123481218595	0.0727816336609912	67.6947647689656
a1664	TP53_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	21	10	2.30258509299405	NA	1.67628076196975	0.847787797708363	0.828492964261385	1.47104921112537	1.31397777007838	0.581742311685026	0.563198673433622	0.630522816388261	0.119190464018511	NA	NA	0.459894772034759	0.130457091051378	67.6947647689656
a1665	SMARCA4_mut	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.50626470953551	2.83492546634508	0.671339243190423	1.3164360592824	0.760117690262254	0.809488800137388	0.509967224352983	0.883204340315773	0.119192445046818	NA	NA	0.304934106669453	0.472173705697431	67.6947647689656
a1666	gain_cnaOV72_(ASXL1)	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	2.3364047688508	3.56745223869859	-1.23104746984779	1.77131128756557	1.593109120781	0.760843377359655	0.694992166814282	0.772732673355289	0.119349643990261	NA	NA	0.617249192300582	0.204035865605153	67.6947647689656
a1667	loss_cnaOV39	272	AR-42	HDAC	9	21	1.63315443905142	NA	-0.576204913538993	0.668513212837124	-1.24471812637612	1.08706451793353	1.97000401321937	0.705847358359456	1.14502691040113	0.631835325219469	0.119482259782948	NA	NA	0.469090438511912	0.0358605938896463	67.6947647689656
a1668	loss_cnaOV102	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	3.07051899234816	2.28824780903593	0.782271183312232	0.781395600355642	0.850088210922632	0.92501778913559	1.00112053735162	0.920223540640806	0.119525277219411	NA	NA	0.59483306563007	0.217274748294733	67.6947647689656
a1669	loss_cnaOV40	1033	Vismodegib	SMO	7	24	2.30258509299405	NA	5.43104637547442	4.75924660045309	0.671799775021337	0.959098487383007	0.77613702182282	0.821915977766544	0.700449207103232	0.865568522222482	0.119562977579067	NA	NA	0.139654110101935	0.125984420263944	67.6947647689656
a1670	gain_cnaOV19	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	5.50688302810572	4.18799134696212	1.31889168114359	0.603450958129787	1.2944503670228	1.04562295578842	2.18558221405613	1.01888161550528	0.119645714269356	NA	NA	0.354570731684156	0.0327947651413233	67.6947647689656
a1671	loss_cnaOV16, loss_cnaOV17	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-0.435221339864502	-1.78546797853366	1.35024663866916	1.95894900744357	1.08907413886015	1.10320315689203	0.689270947604312	1.23981149720657	0.119692971088774	NA	NA	0.598453587114592	0.354584248692767	67.6947647689656
a1672	gain_cnaOV96	158	PF-562271	FAK	3	15	0.940007258491471	NA	3.39969625716839	2.06738854814878	1.33230770901961	1.03409058805771	1.34726716658689	1.01531281395411	1.28838587683312	0.988896443156716	0.119709306522841	NA	NA	0.729053763054073	0.135494054687188	67.6947647689656
a1673	loss_cnaOV84	269	NSC-207895	MDM4	6	25	2.99573227355399	NA	4.82641087949547	3.65902345237271	1.16738742712276	1.29377205937066	1.57668172512632	0.76218287787761	0.902313060996715	0.740407787138672	0.119868005809963	NA	NA	0.705286871897701	0.09035291884226	67.6947647689656
a1674	loss_cnaOV56	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.43272289517212	2.17180150999877	1.26092138517335	1.45172082248831	1.36361817377353	0.920463788508539	0.868570158697645	0.924688017089132	0.119891030281808	NA	NA	0.51448355032802	0.267305803328049	67.6947647689656
a1675	gain_cnaOV96	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	5.23522523734172	4.33263076870804	0.902594468633675	0.601444660198511	1.00298362916407	0.929162614174632	1.50071075256661	0.899909472486537	0.120084958801647	NA	NA	0.358476315165269	0.0457453660231849	67.6947647689656
a1676	loss_cnaOV35	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.67682165736595	2.4726613884415	1.20416026892444	1.42618689659146	1.68975116312902	0.72622955276807	0.844321506390464	0.712625796744308	0.12032387988192	NA	NA	0.628299834945845	0.140749043302855	67.6947647689656
a1677	loss_cnaOV58	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	4.19425794348507	2.28963828957528	1.90461965390979	2.29293580528207	2.23481357136975	0.849271822368455	0.830646740969485	0.852249905007701	0.120433926396587	NA	NA	0.369053785318133	0.142022271493581	67.6947647689656
a1678	gain_cnaOV72_(ASXL1)	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.54612730523777	-3.86080355049425	1.31467624525648	0.438483725722288	1.77118635721558	0.781154029926659	2.99823270086226	0.742257436604944	0.120471067625741	NA	NA	0.22815633324939	0.00389963073473516	67.6947647689656
a1679	loss_cnaOV36	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.5909061117184	3.74299378484723	0.847912326871176	1.31930435499962	0.774896193189896	1.00696420835636	0.642696526891568	1.09422698720548	0.120515029460936	NA	NA	0.936625998042516	0.381747404013316	67.6947647689656
a1680	loss_cnaOV52, loss_cnaOV53	1264	SGC0946	Q8TEK3 (DOT1L)	9	24	-0.693147180559945	NA	2.42340289332742	1.99977812757014	0.423624765757283	0.276255153800163	0.592070456470546	0.800892744227831	1.53345470638251	0.715497220183215	0.120610512475346	NA	NA	0.0359939318336699	0.0092342658459164	67.6947647689656
a1681	loss_cnaOV102	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.77085804009651	4.4994925021995	-0.728634462102983	0.593005116584207	0.718528456370118	1.0250183681191	1.22871530400955	1.01406486499354	0.120740302464716	NA	NA	0.509424860345881	0.153676932260563	67.6947647689656
a1682	loss_cnaOV42	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	2.88839512909174	1.33714655892338	1.55124857016836	1.95388236550002	1.85005360793997	0.833692098301693	0.793931404243659	0.838488443529844	0.120865622791841	NA	NA	0.774884273732894	0.212663557084766	67.6947647689656
a1683	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	2.55355368648096	0.919081517062714	1.63447216941824	2.16596782941399	1.35403484012923	1.1096424226253	0.754615164279913	1.20711234377266	0.12088506339197	NA	NA	0.507376860467343	0.319809903549561	67.6947647689656
a1684	TP53_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	23	10	1.38629436111989	NA	1.44899792441811	0.680300703091259	0.76869722132685	1.22873735859351	1.10599715535035	0.643582693535834	0.625599291785799	0.695026400030249	0.120945517287768	NA	NA	0.250810772286547	0.0922466005543545	67.6947647689656
a1685	loss_cnaOV59	281	CH5424802	ALK	4	28	1.63315443905142	NA	4.46086135064244	3.85142627042051	0.609435080221924	0.584806592730568	0.71773392287483	0.863749755831	1.04211390192501	0.849110040362697	0.12095617334874	NA	NA	0.954177386936922	0.125021900603816	67.6947647689656
a1686	gain_cnaOV72_(ASXL1)	1028	VX-702	p38	4	27	0.693147180559945	NA	3.97098918835887	3.23155885619382	0.739430332165051	0.355501940528988	0.940345999947946	0.823701883959372	2.07996145130678	0.78633857346762	0.12106265941809	NA	NA	0.5025098561869	0.0139776296902394	67.6947647689656
a1687	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.67472966366071	2.47303495874601	1.20169470491469	1.41815984339964	1.69102735458311	0.724635596900348	0.847361960294944	0.710629962110192	0.121073057002063	NA	NA	0.62835616070758	0.139749944206201	67.6947647689656
a1688	PIK3R1_mut	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-1.77402221286317	-2.90962014252819	1.13559792966502	1.6297490333471	1.74685707016485	0.655770475833487	0.696793129757396	0.650080621397292	0.12114815792981	NA	NA	0.685810367607752	0.208140198248071	67.6947647689656
a1689	loss_cnaOV40	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	25	1.6094379124341	NA	2.03562018401846	1.17292437200753	0.862695812010923	2.07551675076605	1.09488674204098	0.654985527165711	0.415653504936789	0.787931553909196	0.121189981848182	NA	NA	0.566720991822323	0.364330782837776	67.6947647689656
a1690	MLL2_mut	1262	UNC1215	LMBL3	3	30	0	NA	2.18102896287398	2.84035107870608	-0.6593221158321	0.542881775664811	0.452500729977827	1.43684081031493	1.21448563091788	1.45706309880297	0.121352143794058	NA	NA	0.0982832834826709	0.162716186653795	67.6947647689656
a1691	PIK3CA_mut	1016	Temsirolimus	MTOR	7	24	-1.6094379124341	NA	-2.07054857696233	-2.01734401582866	-0.0532045611336716	1.75271149738913	1.52355447877438	0.0338084412332727	0.0303555726158731	0.0349213381437282	0.121483120676576	NA	NA	0.0316538367580183	0.943665385993438	67.6947647689656
a1692	gain_cnaOV96	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.6736639674941	-0.471357083141302	1.1450210506354	0.43516057184893	1.42951183606031	0.838652830682375	2.63126102112235	0.800987457222492	0.121550375897206	NA	NA	0.885103931600897	0.00450820129632622	67.6947647689656
a1693	PIK3R1_mut	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.71872967363908	3.96648377601962	0.752245897619455	0.776193757759702	1.13473136540693	0.687775035105644	0.969147059093381	0.662928619541319	0.121590937809446	NA	NA	0.813204046188537	0.105860676153093	67.6947647689656
a1694	loss_cnaOV21, loss_cnaOV22	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-1.33912093993543	0.274202067343666	-1.6133230072791	1.41435605134837	1.57122093321534	1.0335792531072	1.14067670989992	1.02679576956603	0.121592649850697	NA	NA	0.445342701494728	0.175918744688407	67.6947647689656
a1695	gain_cnaOV49	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	-0.536271484956567	0.362863630253655	-0.899135115210223	1.13265531116244	1.11554814459165	0.805200619074389	0.793829425730097	0.806002967751209	0.121666765091165	NA	NA	0.133635522965527	0.300481095617861	67.6947647689656
a1696	loss_cnaOV44	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	5.24420798619381	4.43317802673134	0.811029959462472	1.22655173148071	0.866579485613064	0.905106828576116	0.661227682980303	0.935897944651559	0.12173358953659	NA	NA	0.513132764825626	0.370668347837325	67.6947647689656
a1697	loss_cnaOV33_(ZFHX3)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	3.94687739908889	2.66427126850058	1.28260613058831	1.15337170008269	1.54599021554749	0.848028830659449	1.11204924700021	0.829634054400592	0.121772850221794	NA	NA	0.967719245528704	0.107527750031929	67.6947647689656
a1698	loss_cnaOV58	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.81981732373721	2.19286399230911	0.626953331428105	0.869178228628897	0.877579025191972	0.715353022487765	0.721317344104564	0.714412392993278	0.121856129211683	NA	NA	0.580677983573556	0.193356720857413	67.6947647689656
a1699	gain_cnaOV72_(ASXL1)	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.42484981085899	2.06003757311912	0.364812237739874	0.210372352147885	0.58074403543158	0.666657387466134	1.73412634319658	0.628180774114647	0.122004868649273	NA	NA	0.0360465132953708	0.0215419715340021	67.6947647689656
a1700	SMAD4_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	2.54983096246986	0.919779527814796	1.63005143465506	2.17056308324238	1.35395123164062	1.10609465143678	0.750980907783658	1.2039218227084	0.122044420967934	NA	NA	0.507578198353634	0.321648189529773	67.6947647689656
a1701	SMAD4_mut	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	4.43798869275145	3.57337513418416	0.864613558567292	0.993639233222313	1.02262242472255	0.847858871150036	0.870148369407075	0.845486601569363	0.122059481906645	NA	NA	0.824962645031661	0.180741543887581	67.6947647689656
a1702	gain_cnaOV49	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	2.72767968730958	3.5572002575708	-0.829520570261225	0.856241709958604	0.880205624859102	0.944053855782084	0.968792527405994	0.942416802203474	0.12225166178101	NA	NA	0.787203720137078	0.22885178496764	67.6947647689656
a1703	loss_cnaOV82	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.38763929382975	4.50576111358123	0.881878180248525	0.81646112836377	0.92110163547067	0.964330161466455	1.08012267775179	0.957416799936412	0.122388736089023	NA	NA	0.941089567987421	0.192481891932652	67.6947647689656
a1704	gain_cnaOV50	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	3.33317952234609	4.06392653065779	-0.730747008311707	0.511917698579619	1.20171721261672	0.63559038434924	1.42746970917251	0.608085663282229	0.122468834649076	NA	NA	0.0725353029267169	0.0625815588195316	67.6947647689656
a1705	loss_cnaOV56	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	5.13396160434132	4.13886074913725	0.995100855204078	1.29887289750394	0.911269844654975	1.05737353739193	0.766126429396111	1.09199361862001	0.122500584225314	NA	NA	0.194536731707956	0.314325421024124	67.6947647689656
a1706	loss_cnaOV82	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-1.33565762130392	0.273830997490291	-1.60948861879422	0.44365743325296	1.61355919081094	1.0308785002363	3.62777336332046	0.997477271339097	0.122578132924886	NA	NA	0.445445974222768	0.00227519596706959	67.6947647689656
a1707	loss_cnaOV44	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.18034500301963	-2.89271792770752	1.71237292468789	1.6502571000981	1.71115386895764	1.00305258567025	1.03764008928433	1.00071241736489	0.122793681129822	NA	NA	0.685920055677978	0.206075066212209	67.6947647689656
a1708	loss_cnaOV36	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.3659473247777	4.35697496406124	1.00897236071646	1.04063447985934	0.93748064275597	1.06802557745966	0.969574216734427	1.07625940707461	0.122862995795527	NA	NA	0.0261074666009107	0.229487545032134	67.6947647689656
a1709	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1262	UNC1215	LMBL3	5	28	0	NA	3.13917609304521	2.71634781373494	0.422828279310271	0.555617786252216	0.460258844018522	0.892714659725301	0.761005658516363	0.918674969107721	0.122887258560653	NA	NA	0.0983902817120138	0.168822802340636	67.6947647689656
a1710	gain_cnaOV48_(SOX17)	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	3.29416353948411	4.40926329582428	-1.11509975634018	0.637305580008605	1.31124109716451	0.872175453286189	1.74970970178093	0.850415502344706	0.122937431507248	NA	NA	0.354911928559054	0.0639303937059428	67.6947647689656
a1711	loss_cnaOV20	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.3825022643859	3.74474647239348	0.637755791992423	0.924594645870003	0.825749725245224	0.759994527080551	0.689767991671987	0.7723354576994	0.122999273584726	NA	NA	0.921102555918625	0.206379426875884	67.6947647689656
a1712	loss_cnaOV83	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.66939442486733	2.47398767995911	1.19540674490822	1.41106813243156	1.69260577860936	0.720573697035214	0.847164440492525	0.706252312272239	0.122999362695463	NA	NA	0.628499200562922	0.140007329144416	67.6947647689656
a1713	gain_cnaOV51_(MYC)	346	THZ-2-102-1	CDK7	8	24	0.916290731874155	2.99573227355399	-2.07469509130937	-0.720992594567615	-1.35370249674175	0.76520428308161	2.12292409524879	0.714273440510948	1.76907333985398	0.637659396193864	0.123001315680451	NA	NA	0.427520157092668	0.0127891447402383	67.6947647689656
a1714	loss_cnaOV83	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.0906366972292	0.556367573254492	0.534269123974703	0.71784888293216	0.566822851691422	0.906769508325523	0.744264059856724	0.942568074629354	0.123085505204169	NA	NA	0.0121197261240745	0.176293412313703	67.6947647689656
a1715	loss_cnaOV36	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	4.04045936945601	2.51657496849413	1.52388440096189	1.88297644586909	1.63954382476788	0.920037172866161	0.809295519497876	0.929456338977477	0.123164105372463	NA	NA	0.628511316173919	0.29348556427206	67.6947647689656
a1716	SMAD4_mut	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.82328323655542	4.22199991490791	0.601283321647514	0.795078064320699	0.779092432140442	0.770124395973627	0.756256962215704	0.771774049961666	0.123213329000864	NA	NA	0.208732499327685	0.231575148619742	67.6947647689656
a1717	loss_cnaOV20	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	3.11999424040947	2.64122876009888	0.478765480310595	0.682900969720627	0.520960260241883	0.877924379620499	0.701076000091868	0.919005760800839	0.123319548498197	NA	NA	0.122622043291008	0.197713640104556	67.6947647689656
a1718	loss_cnaOV82	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.71704283641479	3.64234583298681	-0.925302996572016	0.65236656393371	0.943389859718046	0.998346386665782	1.41837894172952	0.980827795677775	0.123385616579761	NA	NA	0.719143496374076	0.113789765718571	67.6947647689656
a1719	loss_cnaOV84	1243	piperlongumine	Increases ROS levels	6	26	2.30258509299405	NA	2.05449037494929	1.512932043151	0.541558331798294	0.749647946681388	0.632960021898113	0.82825353781977	0.722416881411756	0.855596424833082	0.12350982943833	NA	NA	0.193615682188509	0.146679183095056	67.6947647689656
a1720	loss_cnaOV82	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.21204316367096	0.580654430103599	0.63138873356736	0.798629954286005	0.575061505897985	1.06546238034165	0.79058984724889	1.09794991855944	0.123616636833291	NA	NA	0.0121288378827973	0.302554652093769	67.6947647689656
a1721	loss_cnaOV84	1377	Afatinib (rescreen)	ERBB2, EGFR	6	27	2.30258509299405	NA	3.55256776601187	2.45567483581928	1.09689293019259	1.29413346638092	1.72201977040356	0.660587656477134	0.847588721478691	0.63698045112196	0.12367700914201	NA	NA	0.628548919596552	0.11095340212892	67.6947647689656
a1722	loss_cnaOV35	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.92138141687581	5.12311552081515	0.798265896060657	0.80320674441958	0.674503421695773	1.15692329568005	0.993848597022809	1.18348679989455	0.1237508654325	NA	NA	0.105861168256832	0.219714145270547	67.6947647689656
a1723	loss_cnaOV84	223	ZSTK474	PI3K	6	26	1.63315443905142	2.32630161961136	1.36941222867386	0.617230280758118	0.752181947915739	0.409837561338562	1.09348382670955	0.743163797572733	1.83531725461925	0.687876610099631	0.123903258167859	NA	NA	0.764014382120573	0.0110956589075794	67.6947647689656
a1724	loss_cnaOV39	1028	VX-702	p38	10	21	0.693147180559945	NA	3.73071260945316	3.13471046553033	0.596002143922838	0.845421676307471	0.906518960822474	0.671167762151085	0.704976180083273	0.657462413562858	0.123906742788514	NA	NA	0.502789334256687	0.0890669817983144	67.6947647689656
a1725	loss_cnaOV35	1026	17-AAG	HSP90	5	28	0	NA	-1.58331018083333	-0.342889654264462	-1.24042052656887	1.58550075851371	2.35417026998842	0.546521976139108	0.782352527999844	0.526903487985589	0.123972217319004	NA	NA	0.0533280925223765	0.178635001390207	67.6947647689656
a1726	loss_cnaOV87, loss_cnaOV88	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.71726439954336	4.65331794989469	1.06394644964867	0.416205960231592	1.23324732542542	0.890353236632255	2.55629796617197	0.862719446224339	0.124024034661783	NA	NA	0.408095931284277	0.0153257187491865	67.6947647689656
a1727	loss_cnaOV44	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.95265955160234	4.40013490259389	0.552524649008453	0.715368517377411	0.520634291271832	1.03117023937105	0.772363663743612	1.06125289530722	0.124082047053552	NA	NA	0.348206363265375	0.311202674816935	67.6947647689656
a1728	loss_cnaOV43_(NF1)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	3.4083047616923	2.68885935414645	0.719445407545844	1.11476043612709	0.902710063366902	0.771288252166192	0.645381181669262	0.79698392290264	0.124178382121399	NA	NA	0.965027968008116	0.230556128373515	67.6947647689656
a1729	loss_cnaOV41	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.27929937942413	2.97200213419745	-0.692702754773321	0.584071293361747	0.791560392165404	0.902962530577467	1.18599007115437	0.875110429512969	0.124201650761156	NA	NA	0.0158769318867958	0.0554382632391961	67.6947647689656
a1730	loss_cnaOV20	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	3.04100740255949	2.34581312742353	0.69519427513596	0.926938792486014	0.671229993050491	0.961598025884362	0.749989406821	1.03570204301593	0.124308539666005	NA	NA	0.733215020518553	0.234791002557816	67.6947647689656
a1731	loss_cnaOV20	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	7.67101817242572	8.96644907062535	-1.29543089819964	1.58764311672893	1.66158105720806	0.784358778063949	0.815945904057235	0.779637498020309	0.124320547871129	NA	NA	0.918908098593973	0.149866811557589	67.6947647689656
a1732	BRCA1_mut	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.10171484667563	1.56407002867569	0.537644817999947	0.250481052846814	0.690347162021163	0.802374545112141	2.14644905029504	0.778803546357543	0.124330995076735	NA	NA	0.193694160886589	0.031314367571662	67.6947647689656
a1733	PIK3R1_mut	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	1.36335668000274	2.76759951014165	-1.40424283013891	1.00834015331935	1.57290227302179	0.950513743792109	1.39262809828241	0.892771823287628	0.124349794237593	NA	NA	0.203673001401358	0.0378050439115335	67.6947647689656
a1734	TP53_mut	1032	Afatinib	ERBB2, EGFR	21	10	-0.693147180559945	NA	0.673065656484687	-0.306440806314707	0.979506462799394	1.51096851267378	1.84530830116755	0.603843182908021	0.648263980740458	0.530809113132829	0.124457823163978	NA	NA	0.831282412692633	0.16456557157189	67.6947647689656
a1735	loss_cnaOV59	1262	UNC1215	LMBL3	4	29	0	NA	3.18036572334224	2.72524677091157	0.455118952430677	0.61171503676648	0.457565837138602	0.958798391239673	0.744004847153065	0.994652387679931	0.124562705867747	NA	NA	0.0985054513643417	0.235056455698917	67.6947647689656
a1736	PTEN_mut	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.63407730699417	2.74026358147654	0.893813725517635	1.46349994249509	1.37650618203488	0.646531058107752	0.610737110104557	0.649335060883137	0.124612611374594	NA	NA	0.615287873794482	0.402908258744302	67.6947647689656
a1737	loss_cnaOV16, loss_cnaOV17	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	6	26	2.32630161961136	NA	5.53454381762528	5.05195342931792	0.48259038830736	0.574879766939677	0.555418762478753	0.86375930085938	0.8394631644046	0.868876640309429	0.124711393703236	NA	NA	0.0094468164809718	0.102584182183705	67.6947647689656
a1738	loss_cnaOV16, loss_cnaOV17	205	BMS-708163	g-secretase	6	26	2.32630161961136	0.940007258491471	5.46086701856992	4.96995940702416	0.49090761154576	0.481748939123112	0.609787770208379	0.83151196581651	1.0190112975429	0.805046666281951	0.124736581771163	NA	NA	0.0989721679871144	0.0613151384531198	67.6947647689656
a1739	gain_cnaOV51_(MYC)	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	7.44655303174805	6.43017345695195	1.0163795747961	2.07961465191884	1.20789670142611	0.695870312399046	0.488734571021748	0.841445773960727	0.124774912385342	NA	NA	0.30680649906735	0.349208378153482	67.6947647689656
a1740	loss_cnaOV44	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.2174194060186	2.41429534035029	-1.19687593433169	1.11327500089582	1.22046723766775	0.986399307838504	1.07509459331126	0.980670269051098	0.124784754081456	NA	NA	0.838858161664661	0.1940716710844	67.6947647689656
a1741	loss_cnaOV44	1028	VX-702	p38	3	28	0.693147180559945	NA	4.15157535101654	3.23861856491496	0.91295678610158	0.751478078047583	0.900340762285385	1.02478856173739	1.21488146197629	1.01401249876121	0.124795770397241	NA	NA	0.502875218589093	0.156705138197585	67.6947647689656
a1742	loss_cnaOV20	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	4.21835347899029	3.44389400647853	0.774459472511763	1.50843004081693	0.741759067279622	0.880974097776437	0.513420875715477	1.04408494169417	0.124967191270446	NA	NA	0.130154639057147	0.319150181959699	67.6947647689656
a1743	gain_cnaOV19	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	1.22860487828811	-0.0893961684758548	1.31800104676397	0.964180638896952	1.2823410064614	1.05514062944856	1.36696485450257	1.02780854712037	0.125028268320904	NA	NA	0.861335458601461	0.119529878864246	67.6947647689656
a1744	loss_cnaOV56	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.9255120877093	2.89260970019955	1.03290238750975	0.584763745464855	0.987898221548838	1.06817934729217	1.76635845761719	1.04555546814363	0.125070594112114	NA	NA	0.0778574674488172	0.0669373200767983	67.6947647689656
a1745	loss_cnaOV44	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	5.0361396124374	4.22066827897939	0.815471333458007	0.703723191329914	0.773286677891211	1.06085668387876	1.15879559392793	1.05455241474201	0.125140244272927	NA	NA	0.208927199113749	0.171467213253732	67.6947647689656
a1746	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	303	PIK-93	PI4K, PI3K	7	25	2.99573227355399	NA	3.55132359013205	2.7244427464643	0.826880843667748	1.28443269028082	1.18742748756005	0.684814584792744	0.643771253974363	0.696363232559859	0.125202293426538	NA	NA	0.215855372976661	0.160058346334834	67.6947647689656
a1747	PTEN_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	1.94678893320252	2.94014553965732	-0.993356606454807	0.526431249454143	1.60797020124196	0.646322873227695	1.88696360158106	0.617770531871522	0.125280365995944	NA	NA	0.967743471431757	0.0264247281898772	67.6947647689656
a1748	loss_cnaOV43_(NF1)	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	6.14894259472378	4.50037865754055	1.64856393718324	1.52797668564639	1.44940442551506	1.13002963475154	1.07891956249701	1.13740782638869	0.125308296340833	NA	NA	0.100496785300623	0.191606649092849	67.6947647689656
a1749	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	219	AT-7519	CDK9	3	29	2.32630161961136	NA	3.0336102286569	1.33882123820625	1.69478899045065	1.32832412650039	1.66138702738888	1.0325976386175	1.27588512219209	1.02010486570024	0.125335523809494	NA	NA	0.29955697814888	0.142995714346173	67.6947647689656
a1750	loss_cnaOV83	293	MP470	PDGFR	5	27	2.99573227355399	NA	5.09715864984131	3.85518422341268	1.24197442642863	1.26571163982779	1.77900300970052	0.722313201125679	0.981245954724418	0.698129468953345	0.125360766945798	NA	NA	0.60996777858938	0.100760434941645	67.6947647689656
a1751	loss_cnaOV57_(ZNRF3)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.145189228791319	1.4679022399259	-1.32271301113458	1.32480147184469	1.30042314939912	1.01581571580932	0.998423567036654	1.01714046827431	0.125384553380417	NA	NA	0.567093275009076	0.218926451416836	67.6947647689656
a1752	PIK3R1_mut	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.67479531123172	5.16663071592882	0.508164595302906	0.353139383225596	0.761847588766172	0.698164031506362	1.43899156945142	0.667016084051522	0.125388908452928	NA	NA	0.106061747872984	0.113342056768447	67.6947647689656
a1753	loss_cnaOV43_(NF1)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	2.07971381075809	1.00504532360163	1.07466848715646	1.29036044468859	1.47380852932117	0.740414732777838	0.832843638054804	0.729177817726061	0.12539940281954	NA	NA	0.806807299823725	0.144258563319055	67.6947647689656
a1754	loss_cnaOV20	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	3.14739071591636	1.27187631567571	1.87551440024064	2.99068942604926	2.0032167582186	0.848734648345021	0.627117742118152	0.936251353003096	0.12540655681399	NA	NA	0.590256664192672	0.305535899302171	67.6947647689656
a1755	loss_cnaOV85	1114	Cetuximab	EGFR	6	26	4.18661983833127	NA	6.48087533894032	5.67042516009189	0.810450178848424	0.593115381168256	1.34939766490112	0.645571917399363	1.36642920514401	0.600601438648413	0.125429333076442	NA	NA	0.557464574620372	0.0359790768346261	67.6947647689656
a1756	gain_cnaOV72_(ASXL1)	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	2.0196794797838	1.53943622121121	0.480243258572585	0.245912789072286	0.708213042752082	0.721739279430152	1.95290070266097	0.678105639944702	0.125469057323706	NA	NA	0.193801995876286	0.0130053548567016	67.6947647689656
a1757	loss_cnaOV43_(NF1)	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	2.54402694548742	1.07563458751643	1.46839235797099	0.468072132664248	1.45538435700736	1.07525153269758	3.13710698736316	1.00893784580066	0.125477697970814	NA	NA	0.845718455473992	0.00974151922527185	67.6947647689656
a1758	loss_cnaOV41	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.70053610136506	1.31448161701468	1.38605448435038	1.7434727686864	1.88133032534317	0.743775554288159	0.794996348233583	0.736741690536221	0.12553218615814	NA	NA	0.775111115509219	0.159120609562632	67.6947647689656
a1759	loss_cnaOV84	1199	Tamoxifen	ER	6	26	1.6094379124341	NA	4.44008250146047	3.87363672515556	0.566445776304907	0.765729646958792	0.726368363824243	0.772697880690626	0.739746434730103	0.779832664135642	0.125647517539554	NA	NA	0.511130149956504	0.141798871269124	67.6947647689656
a1760	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1066	AZD6482	PI3Kbeta	8	25	1.6094379124341	NA	3.00352981345747	2.17930047231215	0.824229341145315	1.39522502690264	1.22608138964143	0.650920688321193	0.590750112170134	0.672246841122317	0.125669607393165	NA	NA	0.09889157371205	0.163506405726644	67.6947647689656
a1761	loss_cnaOV87, loss_cnaOV88	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.9082671313025	2.98381550857636	0.92445162272614	0.869425980604097	0.885689702562518	1.04499202426867	1.06328962252061	1.04376467294525	0.125746839689246	NA	NA	0.223577008250376	0.198740511795981	67.6947647689656
a1762	gain_cnaOV49	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	3.91791123644579	4.45156918552252	-0.533657949076729	0.677356316516663	0.766966483024394	0.701143399465202	0.787854096970838	0.695803481492887	0.126037043743073	NA	NA	0.0364845749058265	0.303523515866144	67.6947647689656
a1763	loss_cnaOV85	287	KIN001-244	PDPK1 (PDK1)	7	25	2.99573227355399	NA	3.97466462312498	3.42389092658112	0.550773696543865	0.688271938470947	0.922613490744967	0.625348003613203	0.800226866385769	0.59697121499832	0.126099603802395	NA	NA	0.652194325474348	0.108317659194634	67.6947647689656
a1764	loss_cnaOV42	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.8121838599248	2.49551350770664	1.31667035221816	1.60379935262243	1.66442928424605	0.793816307849864	0.820969499747726	0.791064159156862	0.126162560141475	NA	NA	0.628728684222764	0.201183493452356	67.6947647689656
a1765	gain_cnaOV72_(ASXL1)	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.4500314453488	3.89277380133568	0.557257644013124	0.325539221346886	0.783291961283044	0.754243072827557	1.71179878635676	0.711430311502658	0.126266534276213	NA	NA	0.511186448880636	0.0181864561076058	67.6947647689656
a1766	PIK3R1_mut	219	AT-7519	CDK9	5	27	2.32630161961136	NA	2.23731166512698	1.36074400993767	0.876567655189314	2.18747206782948	1.59617419077793	0.519591902652509	0.400721759185291	0.549167916793653	0.126346502454357	NA	NA	0.299661095751093	0.433037059884346	67.6947647689656
a1767	gain_cnaOV4_(KRAS)	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	7.87831435330541	9.01394025938541	-1.13562590608	1.63397498476218	1.65677533057166	0.687389999347315	0.695008134561674	0.685443514956346	0.126353363915283	NA	NA	0.918945215386546	0.138146834144359	67.6947647689656
a1768	loss_cnaOV52, loss_cnaOV53	293	MP470	PDGFR	8	24	2.99573227355399	NA	4.80369885301932	3.7977573523831	1.00594150063622	0.852309698701553	1.91157958302403	0.583607687873012	1.18025349490769	0.526235742194355	0.126522287450852	NA	NA	0.610057410917853	0.0511901109694579	67.6947647689656
a1769	gain_cnaOV4_(KRAS)	290	KIN001-260	IKK	8	23	2.99573227355399	NA	5.27500974587921	4.70250265608928	0.572507089789933	0.794345956497713	0.89514891918936	0.656631524969423	0.720727644053389	0.639566308484616	0.126670577594323	NA	NA	0.653974717546886	0.112140579121703	67.6947647689656
a1770	PIK3R1_mut	1030	KU-55933	ATM	5	28	2.30258509299405	NA	3.44747705183394	4.27662290421941	-0.829145852385469	1.0111011424931	0.989002922012739	0.83593197294929	0.820042444360237	0.838365422316507	0.126690277010212	NA	NA	0.515898179809384	0.145967409156178	67.6947647689656
a1771	gain_cnaOV4_(KRAS)	1067	CCT007093	PPM1D	7	26	1.88706964903238	NA	4.84029016174257	4.39534587935277	0.4449442823898	0.430259357260295	0.727793524859223	0.653909725686363	1.03413040270178	0.611360594992743	0.126717015785179	NA	NA	0.072116957327705	0.0559620405027463	67.6947647689656
a1772	loss_cnaOV40	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-0.241529881862616	-1.43736587917211	1.1958359973095	1.5197502730162	1.16636490747713	0.963252656488912	0.786863485759514	1.02526746959158	0.126767125194018	NA	NA	0.0395920706162268	0.159640281336397	67.6947647689656
a1773	loss_cnaOV87, loss_cnaOV88	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	5.09324098638661	4.10431968575618	0.988921300630428	1.39536134237551	0.893779155296738	1.0569674326974	0.70872058053927	1.10644927750872	0.126771263583539	NA	NA	0.0412629540882857	0.343854430156742	67.6947647689656
a1774	loss_cnaOV81_(RB1)	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	2.36213799836426	0.458150648786797	1.90398734957746	1.22939545863763	2.32225194573562	0.851088259422585	1.54871838528458	0.819888364427373	0.126772481944524	NA	NA	0.943938216970218	0.0414922451497293	67.6947647689656
a1775	loss_cnaOV52, loss_cnaOV53	219	AT-7519	CDK9	8	24	2.32630161961136	NA	0.839422826680516	1.71713599918783	-0.877713172507311	1.36990444450429	1.75530282501033	0.524529290604259	0.640711237946904	0.500035184813278	0.126801093283393	NA	NA	0.299707612056686	0.165290075466331	67.6947647689656
a1776	PIK3R1_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-0.504715938648236	-2.2549968486458	1.75028090999757	1.8475004416584	1.95883332447252	0.89996789137841	0.947377803291043	0.893532332807787	0.126870808560123	NA	NA	0.262657330176778	0.103640305608032	67.6947647689656
a1777	loss_cnaOV70	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	3.11192108789691	1.36751451388038	1.74440657401653	1.91830005357016	1.85794956745847	0.93682863599318	0.909350219101542	0.9388880110469	0.126940174504849	NA	NA	0.775177682557849	0.25092397795504	67.6947647689656
a1778	gain_cnaOV48_(SOX17)	333	T0901317	LXR	3	29	2.32630161961136	NA	4.13020051909045	4.81781567199391	-0.687615152903465	0.436081678340519	1.14269295950522	0.619655397562342	1.5768035830355	0.601749706413875	0.126954363823348	NA	NA	0.00390960406395891	0.0846949643021185	67.6947647689656
a1779	loss_cnaOV58	1017	Olaparib	PARP1, PARP2	5	26	1.6094379124341	NA	4.8170859816421	3.80666555803593	1.01042042360617	0.633207613627106	1.17147015254876	0.907985909101311	1.59571742641933	0.862523403953405	0.127077367701899	NA	NA	0.0728179746542832	0.0192756769598787	67.6947647689656
a1780	loss_cnaOV21, loss_cnaOV22	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	7.30682437724807	8.91293905595155	-1.60611467870349	1.70939483228599	1.64774978104922	0.972180237729423	0.939580867081255	0.974732145120224	0.12710579798995	NA	NA	0.91895878172795	0.239493305170102	67.6947647689656
a1781	SMAD4_mut	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	5.18234005497536	4.18727687149239	0.995063183482967	1.00709855507345	1.30303914027113	0.778975583222231	0.988049459976039	0.763647961699689	0.127122082052962	NA	NA	0.355331295084287	0.141195162102362	67.6947647689656
a1782	loss_cnaOV102	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.46621652580347	3.73505280382284	1.73116372198063	1.85584420739453	1.63001199425628	1.05136849409241	0.932817375016118	1.06205581804354	0.127249279000814	NA	NA	0.133662042075705	0.242593153050541	67.6947647689656
a1783	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.69703706160271	1.49593622939625	1.20110083220646	1.04189832759797	1.47732341894509	0.841717563613651	1.1528004224515	0.813024972598163	0.127338312651411	NA	NA	0.310062412606615	0.0617533757506407	67.6947647689656
a1784	BRCA1_mut	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	3.23085532064259	2.44134656613268	0.789508754509911	0.985145006874994	1.01180674585732	0.782267026770445	0.801413750260314	0.780295997968416	0.127346054513775	NA	NA	0.379542297190178	0.209874059895797	67.6947647689656
a1785	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	5.12383582018562	4.32236298012182	0.801472840063798	0.64068175035156	0.745609323032736	1.08475498590513	1.2509687370118	1.07492330809899	0.127483087812622	NA	NA	0.0365405108708971	0.149214194454032	67.6947647689656
a1786	KRAS_mut	1371	PLX4720 (rescreen)	BRAF	7	26	2.30258509299405	NA	3.96985941912443	4.67861938032714	-0.708759961202718	1.31872116394349	0.838117412701499	0.745827589938655	0.537460064023884	0.845657124481134	0.127699295788129	NA	NA	0.309717544991049	0.21694781518106	67.6947647689656
a1787	loss_cnaOV87, loss_cnaOV88	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.33510515696888	-4.78930389567428	1.4541987387054	2.28924556627674	1.26704464260698	1.06738741517914	0.635230558105013	1.14770915704544	0.127772552037024	NA	NA	0.122382774507333	0.386053487654524	67.6947647689656
a1788	loss_cnaOV39	1010	Gefitinib	EGFR	10	20	-0.693147180559945	NA	1.41694200857192	0.679668003469654	0.737274005102262	0.998737738057955	1.32447284268855	0.599789116198294	0.738205814206932	0.556654679008494	0.127831281748978	NA	NA	0.955875575214132	0.101921542585812	67.6947647689656
a1789	loss_cnaOV36	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	1.33604031562115	-0.317829288003573	1.65386960362472	2.02802901793166	1.49901125574088	1.07301075498916	0.815505887243893	1.1033069947212	0.12786210278659	NA	NA	0.0893976340419323	0.291032450035369	67.6947647689656
a1790	gain_cnaOV48_(SOX17)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	4.79612428875799	5.17826480006012	-0.382140511302134	0.529073363842508	0.583804623238805	0.65850362785777	0.722282650040736	0.654569176211918	0.128124392920183	NA	NA	0.00949378107194747	0.337240162042182	67.6947647689656
a1791	PIK3CA_mut	274	PXD101, Belinostat	HDAC	6	24	2.99573227355399	NA	0.22198262507355	1.01295655542668	-0.790973930353133	0.854862566681727	2.2473876686685	0.382361624016192	0.925264435689836	0.351952598735116	0.12821850144808	NA	NA	0.398914867393038	0.183476569307872	67.6947647689656
a1792	gain_cnaOV4_(KRAS)	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.8039647706649	-1.04549348167113	-0.758471288993772	0.913682441722843	1.36536241714801	0.578807400216643	0.830125713659985	0.555509130372931	0.128231972544354	NA	NA	0.0396734954621739	0.218048038754352	67.6947647689656
a1793	loss_cnaOV39	268	YM155	BIRC5 (Survivin)	9	21	1.63315443905142	NA	-5.14256199657372	-3.72627005005247	-1.41629194652125	0.885030059195503	2.62647824490868	0.624019268212859	1.6002755294082	0.53923612322572	0.128261413332136	NA	NA	0.925353079278275	0.0366995656892899	67.6947647689656
a1794	gain_cnaOV18_(CCNE1)	1026	17-AAG	HSP90	4	29	0	NA	1.33003268983592	-0.787503171824665	2.11753586166058	1.69707396004721	2.25053987080396	0.961177670135432	1.24775696965009	0.940901287344949	0.128306472254957	NA	NA	0.0535314527863679	0.0799548474690203	67.6947647689656
a1795	gain_cnaOV94	292	Masitinib	KIT	7	25	2.99573227355399	NA	4.63411187097552	3.83975481421169	0.794357056763833	1.13419989185282	0.967443099032526	0.791969384112518	0.700367776852968	0.821089175743996	0.128392151970979	NA	NA	0.0936709419563965	0.12704865490026	67.6947647689656
a1796	gain_cnaOV4_(KRAS)	1049	PD-173074	FGFR1, FGFR3	7	26	0.693147180559945	NA	3.48903108602402	2.851215756421	0.637815329603021	0.735498822615051	1.02774652463769	0.652148396841183	0.867187424359541	0.620595948819062	0.128407756677731	NA	NA	0.078053608137363	0.0858625124543444	67.6947647689656
a1797	loss_cnaOV84	1218	JQ1	BRD2, BRD3, BRD4	6	25	0	NA	2.74980712671221	2.18458830633798	0.565218820374235	0.733241210562812	0.905764404138576	0.643434965052691	0.770849772533095	0.624024103609795	0.128492478378934	NA	NA	0.581243107086727	0.140382715044735	67.6947647689656
a1798	KRAS_mut	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	9.61957899128106	8.50607140664251	1.11350758463855	1.56151011437187	1.67840196830572	0.672856941464239	0.713096619989854	0.66343319756863	0.128498923761464	NA	NA	0.918983659593802	0.132575733655181	67.6947647689656
a1799	loss_cnaOV84	1268	XAV 939	TNKS1 (tankyrase-1)	6	26	1.6094379124341	NA	3.3551380803441	2.7406452621489	0.614492818195204	1.3273755204118	0.988402100662267	0.583837563205969	0.462938187985089	0.62170327014023	0.128552168396724	NA	NA	0.29061062926528	0.3246074227836	67.6947647689656
a1800	loss_cnaOV36	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	3.00488541642912	2.21781764890841	0.787067767520709	0.890279844821865	0.874750572800496	0.898653175488079	0.884067826648589	0.899762506014632	0.128710527315158	NA	NA	0.581261111453236	0.260761673329886	67.6947647689656
a1801	KRAS_mut	292	Masitinib	KIT	7	25	2.99573227355399	NA	3.3677123322126	4.19434668506531	-0.826634352852713	0.569189824248033	1.07918120888261	0.828084324153895	1.45229994922132	0.765982900785136	0.128823202177331	NA	NA	0.0936994989233686	0.0136931406507316	67.6947647689656
a1802	loss_cnaOV58	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	0.327127119130492	1.48993784917693	-1.16281073004644	1.14125875402214	1.31985751645871	0.892740676692504	1.01888439054539	0.881012318031392	0.128854025254602	NA	NA	0.567390727484569	0.131333614984262	67.6947647689656
a1803	loss_cnaOV59	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	3.31980681547871	2.17027889091769	1.14952792456102	0.402284572960178	1.47198479511773	0.819785650883955	2.85749939676363	0.780937363194085	0.128873123793226	NA	NA	0.814848110796453	0.00355508016370626	67.6947647689656
a1804	loss_cnaOV1	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	1.99168797070995	3.81746147583969	-1.82577350512974	4.95426421586751	1.54895990395238	0.927417213575132	0.368525663060552	1.17870933939028	0.12888386559561	NA	NA	0.738974641727256	0.58919553105727	67.6947647689656
a1805	loss_cnaOV57_(ZNRF3)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	1.772853191378	0.740166858994457	1.03268633238354	2.54680240303517	0.946357463825026	0.856226486470105	0.405483492222572	1.09122226205052	0.128996501465538	NA	NA	0.839592057031856	0.478601037162723	67.6947647689656
a1806	PTEN_mut	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	4.0779387602021	3.22221730590859	0.855721454293508	1.48123991263092	1.05208815920406	0.787966391272275	0.577706181825472	0.81335527522797	0.129023663522137	NA	NA	0.949227574452003	0.423569033333535	67.6947647689656
a1807	loss_cnaOV42	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.56979441025919	2.05262494691702	0.51716946334217	0.521579471819462	0.537568834619798	0.964792223271914	0.991544896385763	0.962052541062845	0.129025991923609	NA	NA	0.0363022713058446	0.138853281501057	67.6947647689656
a1808	loss_cnaOV1	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.155551013353424	1.46679204872282	-1.31124103536939	1.33307057390317	1.3009630462061	1.00616809654918	0.983624619010335	1.0079002929355	0.129026438430844	NA	NA	0.567405272140454	0.223913442552313	67.6947647689656
a1809	loss_cnaOV83	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.49673631528769	4.9814987080596	0.515237607228088	0.43137985826158	0.612904840652135	0.8704416249775	1.19439421512271	0.840648617948379	0.129084418056451	NA	NA	0.0992735467553204	0.0548153179016253	67.6947647689656
a1810	loss_cnaOV33_(ZFHX3)	341	EX-527	SIRT1	4	27	2.99573227355399	NA	6.21900319174812	5.70728510661451	0.511718085133605	0.562936631863272	0.538460448132129	0.945797860552366	0.909015431168269	0.950335511008672	0.129156640194122	NA	NA	0.0989803951545769	0.165773762756171	67.6947647689656
a1811	loss_cnaOV85	1371	PLX4720 (rescreen)	BRAF	7	26	2.30258509299405	NA	5.09048897938712	4.37691142179488	0.713577557592233	0.799943605315752	0.982200044179458	0.751404481575581	0.892034829518477	0.726509392685239	0.129206825734755	NA	NA	0.309864521633894	0.0710425640875918	67.6947647689656
a1812	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	5.1679448731619	3.72558932825412	1.44235554490778	1.46782000420832	1.4720256292164	0.980173085472428	0.98265151092945	0.979844043663546	0.129572758619859	NA	NA	0.727211829625705	0.222336720771772	67.8001714431587
a1813	loss_cnaOV42	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	3.4235102464793	2.23505894239815	1.18845130408115	1.86796437554948	1.17092378342924	0.946664457462715	0.63622803498678	1.01496896800625	0.12989193170864	NA	NA	0.0991725018750187	0.295335747900555	67.8001714431587
a1814	loss_cnaOV54	1031	Elesclomol	HSP70	10	21	-1.6094379124341	NA	-3.5002747470557	-4.32620063525058	0.825925888194873	1.93161876166642	1.23188246832999	0.556268115129087	0.427582245826987	0.670458350880297	0.129898403315756	NA	NA	0.859280180840521	0.238416367001483	67.8001714431587
a1815	loss_cnaOV83	326	GSK690693	AKT	5	27	2.32630161961136	NA	5.18003065749019	3.96154235079772	1.21848830669247	0.832005527047644	1.46487856343765	0.872119059724724	1.46451948584555	0.83180158212776	0.129917864409063	NA	NA	0.0833066418155649	0.0272338020323188	67.8001714431587
a1816	gain_cnaOV72_(ASXL1)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	0.0500342002081653	1.1808709978899	-1.13083679768174	0.72435948967609	1.58970477391542	0.752193826062385	1.56115411449557	0.71135019296476	0.130027798495141	NA	NA	0.783993101059016	0.0250446085398178	67.8001714431587
a1817	loss_cnaOV87, loss_cnaOV88	1248	FK866	NAMPT	3	29	0	NA	0.858647243309636	-1.9739099898456	2.83255723315523	2.52627009227438	2.65489701456164	1.07029650267835	1.12124085299411	1.06691793226598	0.130046760439787	NA	NA	0.0381789780135596	0.181998217052715	67.8001714431587
a1818	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	304	SB52334	ALK5	3	29	2.99573227355399	NA	5.17469652140294	4.28304847170939	0.891648049693547	0.982540465305134	1.04080564558462	0.859814989061471	0.907492445531635	0.856690250937976	0.130452473210251	NA	NA	0.335776569700318	0.251168994134757	67.8001714431587
a1819	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1129	PF-4708671	RPS6KB1 (p70S6KA)	8	24	2.30258509299405	NA	4.62419026274832	4.05464465600427	0.569545606744055	1.17120513522006	0.86908545991544	0.600641162505318	0.486290223306649	0.655339012114494	0.130558699912358	NA	NA	0.041414651331246	0.235640573607857	67.8001714431587
a1820	KRAS_mut	219	AT-7519	CDK9	7	25	2.32630161961136	NA	0.519256231689914	1.7716741188849	-1.25241788719499	1.32758849063638	1.7013574955056	0.766726924864216	0.943378084420302	0.736128585851851	0.13067149953998	NA	NA	0.300096310151821	0.0608711798643631	67.8001714431587
a1821	ARID1A_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	3.92922268125064	3.29830075754936	0.630921923701284	1.35287936159528	0.991814063460868	0.580100231335249	0.46635490318761	0.636129237268248	0.130687985242142	NA	NA	0.758973985367926	0.378763374112914	67.8001714431587
a1822	gain_cnaOV4_(KRAS)	226	GSK1070916	AURKB	8	24	0.940007258491471	2.32630161961136	1.63692913157452	2.53965013145892	-0.902720999884395	2.28910052307046	0.978977038220551	0.645223444497121	0.394356207071912	0.922106407648985	0.130698257735969	NA	NA	0.814917644279701	0.310915286306109	67.8001714431587
a1823	gain_cnaOV51_(MYC)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	8	23	2.32630161961136	NA	1.59411003361914	2.53720568245778	-0.943095648838637	0.818618859672068	1.48871947485373	0.694678666498786	1.15205707478622	0.63349453323387	0.130800578466042	NA	NA	0.515512601539904	0.0364958899474691	67.8001714431587
a1824	PIK3CA_mut	268	YM155	BIRC5 (Survivin)	6	24	1.63315443905142	NA	-5.21430685463169	-3.88537032885314	-1.32893652577855	1.11164509933718	2.48661745166081	0.577265003188994	1.1954683437825	0.534435453628364	0.130813606689385	NA	NA	0.925396011582985	0.0659380762375869	67.8001714431587
a1825	loss_cnaOV33_(ZFHX3)	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	2.85324763046628	1.34216763015559	1.51108000031069	1.97453647671949	1.85192566714108	0.810426278952755	0.765283406068651	0.815950676164785	0.130942362193303	NA	NA	0.775362404016773	0.226284918175213	67.8001714431587
a1826	loss_cnaOV87, loss_cnaOV88	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.0688261121831177	-0.895428896690161	0.826602784507043	0.131211254712044	0.800525241562349	1.0690727298819	6.29978568775294	1.03257554114571	0.130966898404109	NA	NA	0.0692438210786365	6.30395942759098e-05	67.8001714431587
a1827	loss_cnaOV102	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	4.70849034492943	3.23716425014923	1.4713260947802	0.546816951600468	1.67383159217301	0.906420518698333	2.69071046622421	0.879016802921066	0.130981328657417	NA	NA	0.618139375511052	0.0120711670257627	67.8001714431587
a1828	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	2.85781425575061	0.99953705526923	1.85827720048138	2.40687029383799	2.21391161906878	0.829365970454882	0.772072016194183	0.839363768849552	0.131054394109468	NA	NA	0.347530224659722	0.165720229499398	67.8001714431587
a1829	loss_cnaOV36	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.57921418272794	2.25910359224266	1.32011059048528	2.25576463043089	1.1580711742875	1.04926341073299	0.585216459499641	1.13992181119393	0.131094839942449	NA	NA	0.0992507530204599	0.417848034156079	67.8001714431587
a1830	gain_cnaOV96	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	5.23626499390288	4.40356506197681	0.832699931926077	0.707851579218738	1.01192452301121	0.852420225420879	1.17637645570437	0.822887392281183	0.131172898312597	NA	NA	0.177050095302097	0.0578471101775163	67.8001714431587
a1831	gain_cnaOV96	1262	UNC1215	LMBL3	4	29	0	NA	3.17466518594827	2.72603305193142	0.448632134016842	0.357926560958162	0.486280376422131	0.943741481209261	1.25341950822499	0.922579145220108	0.131240650664231	NA	NA	0.098948634803916	0.0789419685318319	67.8001714431587
a1832	KRAS_mut	230	GSK429286A	ROCK2	7	25	2.99573227355399	2.32630161961136	4.97497634228371	5.69660124658818	-0.721624904304461	1.33918957250287	0.809021149371135	0.76825232920307	0.538851943833302	0.891972854931409	0.13124408488648	NA	NA	0.288262290341393	0.215111436421303	67.8001714431587
a1833	NF1_mut	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	2.56522952794185	3.91079996161532	-1.34557043367347	2.06511111549708	1.43377247234444	0.893189599967025	0.651572897737071	0.93848254142671	0.131247859173261	NA	NA	0.152104716827388	0.286389174104864	67.8001714431587
a1834	loss_cnaOV1	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	-0.103174316292085	1.29497870211707	-1.39815301840916	1.72002271691649	1.42585056601461	0.966485898923203	0.812868925891659	0.980574719212781	0.131349202148582	NA	NA	0.807038162347697	0.291988312556433	67.8001714431587
a1835	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1038	NU-7441	PRKDC (DNAPK)	8	25	0.693147180559945	NA	3.02953213886433	2.37944858358014	0.650083555284189	1.14676610105174	0.957447120187776	0.647929871530845	0.566884175149555	0.678975936714598	0.131399250605415	NA	NA	0.379930141918522	0.176805287565632	67.8001714431587
a1836	KRAS_mut	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.9073208283602	2.94623084795261	0.961089980407592	1.34722025070341	0.817952032349358	1.0719456451558	0.713387421177635	1.17499552834059	0.131483753612128	NA	NA	0.651426539269776	0.34134513401441	67.8001714431587
a1837	loss_cnaOV33_(ZFHX3)	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.94685006076619	4.1823817028048	0.764468357961394	1.22628158891674	0.814637277338616	0.884119910283191	0.623403600666223	0.938415635065066	0.131561537551336	NA	NA	0.507548856442766	0.304112385151356	67.8001714431587
a1838	gain_cnaOV48_(SOX17)	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	1.1801314235968	2.80260776308005	-1.62247633948325	3.14852821277229	1.48989399754714	0.984470391737417	0.515312625404317	1.08898776836097	0.13160608833377	NA	NA	0.629108749859042	0.467011738966625	67.8001714431587
a1839	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	329	QL-XI-92	DDR1	7	25	2.32630161961136	NA	5.02454400350441	4.39623094473429	0.628313058770121	0.753296936029093	1.04062375660373	0.634753733234656	0.834084182105122	0.6037850421758	0.131993026197871	NA	NA	0.177121192154484	0.0978584135110346	67.8001714431587
a1840	SMARCA4_mut	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	2.91249392874304	3.89290090474324	-0.980406976000203	0.652397592223388	1.01706324963335	0.983444947862546	1.50277528256803	0.963958707930541	0.132007548222733	NA	NA	0.708027918034329	0.0991344107377616	67.8001714431587
a1841	gain_cnaOV72_(ASXL1)	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	5.09141271068973	4.16797592641901	0.92343678427072	0.868635789310058	1.32537908102967	0.723885456492708	1.06308857594296	0.696734087241905	0.13202940199414	NA	NA	0.355803890262978	0.0816206240353125	67.8001714431587
a1842	loss_cnaOV84	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.95820880753452	2.32572732027988	0.632481487254632	0.827508138178266	0.690521172770852	0.872285410902939	0.764320564444261	0.915948000141221	0.132047411786745	NA	NA	0.733987460005843	0.176062416966862	67.8001714431587
a1843	loss_cnaOV39	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	5.72740251581979	7.04415578406919	-1.3167532682494	0.964490711799439	1.51818385569641	0.935436284130126	1.36523167319335	0.867321348009847	0.132150473587729	NA	NA	0.30815235438848	0.0471531339935277	67.8001714431587
a1844	loss_cnaOV44	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.8617623645228	3.80509748924477	1.05666487527803	0.866575167125898	1.0478476146709	1.01885596377433	1.21935743760416	1.00841464014774	0.13219024783731	NA	NA	0.301069979465453	0.156093193798903	67.8001714431587
a1845	loss_cnaOV87, loss_cnaOV88	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.23354239547289	1.55043269604149	0.683109699431399	0.938075951666473	0.633215688299216	1.03824089293355	0.728202975694952	1.07879465410308	0.132221156042615	NA	NA	0.194420559725827	0.333489028300962	67.8001714431587
a1846	loss_cnaOV81_(RB1)	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	2.52497904742061	1.07971627995932	1.44526276746129	0.438779853035799	1.46117686202356	1.05517908665077	3.29382207834273	0.989108714368615	0.132280584432135	NA	NA	0.846179272052277	0.00894774923548648	67.8001714431587
a1847	loss_cnaOV58	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.79445498029494	4.81055526581847	0.983899714476475	0.525058501494755	1.26340465566951	0.825634249402853	1.87388588447854	0.778768472999718	0.132330780431311	NA	NA	0.356811159395129	0.011003286684895	67.8001714431587
a1848	loss_cnaOV83	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.66663717576146	5.7017770533209	0.964860122440562	0.439452932274791	1.31438092974255	0.769026639447384	2.19559377484648	0.734079520333236	0.132344701970984	NA	NA	0.558037184439031	0.0120416805095937	67.8001714431587
a1849	loss_cnaOV38	1036	PLX4720	BRAF	8	25	2.30258509299405	NA	4.98492065778177	4.09124096923707	0.893679688544698	1.00104585464046	1.32617474059852	0.70920621913396	0.89274600599158	0.673877778837329	0.132451615964955	NA	NA	0.355843630611087	0.0607927648940763	67.8001714431587
a1850	gain_cnaOV18_(CCNE1)	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.77265929830428	0.205428315289946	1.56723098301434	1.11501486835266	1.65175893457264	0.967151952643679	1.40556958252026	0.948825491547791	0.132471822197226	NA	NA	0.831574911931592	0.115052842169735	67.8001714431587
a1851	gain_cnaOV19	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.77265929830428	0.205428315289946	1.56723098301434	1.11501486835266	1.65175893457264	0.967151952643679	1.40556958252026	0.948825491547791	0.132471822197226	NA	NA	0.831574911931592	0.115052842169735	67.8001714431587
a1852	ARID1A_mut	1001	AICAR	AAPK1 (AMPK) agonist	9	22	7.60090245954208	NA	8.21384319945489	8.96874766446534	-0.754904465010455	1.02059144085388	1.25400196081176	0.632153882123235	0.73967352144249	0.601996239720212	0.132503315652551	NA	NA	0.515664223301721	0.0978260613929454	67.8001714431587
a1853	gain_cnaOV18_(CCNE1)	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.44915724045364	5.87799005285632	0.571167187597319	0.430113740410422	0.70330417152097	0.837896040979981	1.32794452707394	0.812119721061954	0.132536562568973	NA	NA	0.905723882714702	0.0672892517878548	67.8001714431587
a1854	ARID1A_mut	1033	Vismodegib	SMO	9	22	2.30258509299405	NA	4.41391938822236	5.11427129750881	-0.700351909286456	0.787994013446103	0.808281343140151	0.872456031707803	0.888778210666392	0.86647046258127	0.132685867078169	NA	NA	0.140778480306853	0.0411858149435905	67.8001714431587
a1855	loss_cnaOV58	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.4192109371616	2.75153891156029	0.667672025601307	1.31964536028911	1.00436334024773	0.634744515672348	0.505948071878215	0.664771401788344	0.132700043796781	NA	NA	0.291019461229941	0.332421120667741	67.8001714431587
a1856	loss_cnaOV16, loss_cnaOV17	346	THZ-2-102-1	CDK7	6	26	0.916290731874155	2.99573227355399	-0.0849540773270989	-1.28429455908212	1.19934048175502	1.86149705198619	1.94331920341055	0.621444701664436	0.644288144574467	0.617160824454451	0.132713359764763	NA	NA	0.42846730763593	0.197262682720292	67.8001714431587
a1857	gain_cnaOV72_(ASXL1)	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.96686039539098	4.08705543801875	0.879804957372224	0.961782696629156	0.931668878466925	0.94124579406865	0.914764801296336	0.94433223831621	0.132945816739565	NA	NA	0.0415079484992887	0.163698732609794	67.8001714431587
a1858	loss_cnaOV83	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.45308279687074	3.72738225497983	0.72570054189091	0.909889486700517	0.834718151605816	0.857937932377947	0.797569982396959	0.869395903868653	0.13303774825935	NA	NA	0.936874850721671	0.213188983399598	67.8001714431587
a1859	gain_cnaOV95_(MECOM)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	9	22	2.32630161961136	NA	1.68579066038566	2.54256795554596	-0.856777295160304	0.868210262092906	1.51200851930106	0.627638780823349	0.986831568996844	0.566648457481151	0.133050367827728	NA	NA	0.51571276176377	0.0589393944938231	67.8001714431587
a1860	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	152	CP466722	ATM	7	25	2.77258872223978	NA	3.05379284091985	2.53299136135937	0.520801479560481	0.722035890959957	0.805979294362376	0.659322005545637	0.721295833186447	0.646172281599983	0.133069399851944	NA	NA	0.542731363356443	0.129668485246454	67.8001714431587
a1861	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.903180727009238	0.0235095527975126	-0.926690279806751	1.41818896192371	0.886559138198011	0.994848217365673	0.653432162206184	1.04526617557663	0.13306969181537	NA	NA	0.535609787626663	0.375153714758929	67.8001714431587
a1862	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	2.35388948176653	1.39666542311197	0.957224058654566	1.80216193947057	0.814212810013746	0.94217243982055	0.531153187563031	1.17564357485165	0.133328741111407	NA	NA	0.432322026480798	0.369112988231338	67.8001714431587
a1863	loss_cnaOV1	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.98081561293622	0.808160493196429	1.17265511973979	0.331715855167438	1.27095597515623	0.95498657420777	3.53511929403519	0.922655971301956	0.133376876112982	NA	NA	0.955930315120549	0.00285071843058457	67.8001714431587
a1864	loss_cnaOV43_(NF1)	1010	Gefitinib	EGFR	5	25	-0.693147180559945	NA	1.70747679049929	0.769015848104632	0.938460942394656	0.266687907051595	1.32251876032828	0.763872834195565	3.51894824467274	0.70960123254638	0.133583458676308	NA	NA	0.955932303678434	0.0031340656071377	67.8001714431587
a1865	loss_cnaOV54	295	NVP-BHG712	EPHB4	10	22	2.32630161961136	NA	2.72152629704657	3.4918586042363	-0.77033230718973	0.996281421024931	1.04690293347837	0.746462495526766	0.773207540493173	0.735820182135008	0.133844674264542	NA	NA	0.054552087558432	0.0611162951623363	67.8001714431587
a1866	gain_cnaOV48_(SOX17)	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	3.68207714493282	4.8713737271744	-1.18929658224158	0.928225448160965	1.20065088727136	1.00457762627124	1.28125832425501	0.990543208562822	0.133979390599417	NA	NA	0.409105193873409	0.140955425616475	67.8001714431587
a1867	TP53_mut	184	BMS-754807	IGF1R	11	6	0.940007258491471	NA	0.498264607383924	1.36251324883311	-0.864248641449187	0.859958680412034	1.21973832530749	0.869068030751665	1.00498856646821	0.708552501399277	0.13407184751362	NA	NA	0.322737095421706	0.16326632514256	67.8001714431587
a1868	BRCA1_mut	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.373270693094	4.50724752055389	0.866023172540105	0.296508532493065	0.944697946035731	0.945574026825998	2.92073609234285	0.916719652217122	0.134139776696181	NA	NA	0.941236377578468	0.00802937057130774	67.8001714431587
a1869	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	10.1592026946892	8.60732709336858	1.55187560132058	0.620753051742964	1.70885131435255	0.936607306793849	2.49998867820817	0.908139630573155	0.134175182150879	NA	NA	0.919081930838852	0.0171631508656899	67.8001714431587
a1870	loss_cnaOV52, loss_cnaOV53	1001	AICAR	AAPK1 (AMPK) agonist	8	23	7.60090245954208	NA	9.36043591027815	8.5371108752655	0.823325035012653	0.719182973251414	1.30299754655718	0.692668660195707	1.1448060724942	0.631869981020352	0.134276588848983	NA	NA	0.5158200270061	0.0372733588952629	67.8001714431587
a1871	gain_cnaOV96	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	9.66920067426087	8.61334202652919	1.05585864773168	0.699573538715332	1.23480796608982	0.886792302664544	1.50928900151171	0.855079232340229	0.13434143734744	NA	NA	0.51582568047614	0.045131284246291	67.8001714431587
a1872	loss_cnaOV43_(NF1)	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	3.55099933001655	2.05793491185577	1.49306441816077	1.50188383311089	1.74844879463639	0.868756309600592	0.994127764907191	0.853936599539521	0.134499206121059	NA	NA	0.0999514375164313	0.0922010121772972	67.8001714431587
a1873	loss_cnaOV43_(NF1)	326	GSK690693	AKT	5	27	2.32630161961136	NA	5.17000197536973	3.96339951415336	1.20660246121637	0.95269105058638	1.4551322105529	0.862716655944765	1.26652020135353	0.829204695261269	0.134618234591956	NA	NA	0.0835896736848368	0.0455878908978004	67.8001714431587
a1874	PIK3R1_mut	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.84482103270992	2.8552132958928	0.989607736817125	1.01055749459996	1.66511802869679	0.621045258270726	0.979269108492313	0.594316871093905	0.13463651878573	NA	NA	0.652956579012724	0.108880160546558	67.8001714431587
a1875	loss_cnaOV41	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.86425082306509	4.16936421504717	0.694886608017915	1.07959144232563	0.826849644861324	0.803498047004447	0.643657017622337	0.840402620157694	0.134702362111961	NA	NA	0.507818638564482	0.230936550067529	67.8001714431587
a1876	loss_cnaOV20	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.08042335946151	0.558258932100359	0.522164427361155	0.610022946413215	0.587699440221038	0.883938779453097	0.855975058694683	0.888488896917725	0.134789436834531	NA	NA	0.0123121294315889	0.132251356387302	67.8001714431587
a1877	loss_cnaOV55	1218	JQ1	BRD2, BRD3, BRD4	6	25	0	NA	2.74207854520313	2.18644316590016	0.555635379302974	0.397261540511642	0.949581599180438	0.631792066600954	1.39866390939168	0.585137053816681	0.134831906989455	NA	NA	0.581752893561686	0.0376427484661949	67.8001714431587
a1878	loss_cnaOV16, loss_cnaOV17	1219	PFI-1	BRD2, BRD3, BRD4	6	26	2.30258509299405	NA	2.80001907557957	2.26040880713881	0.539610268440762	0.78154397961834	0.863609579436996	0.634475771702004	0.690441334733684	0.624831267842749	0.134860223418148	NA	NA	0.596039483405375	0.173181095235984	67.8001714431587
a1879	PIK3R1_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	-1.14807191355503	-0.186940713333793	-0.961131200221241	1.81552244063532	1.29516629794207	0.699802462780753	0.529396485942033	0.742090959090281	0.135011409225778	NA	NA	0.885419108217539	0.310949727918134	67.8001714431587
a1880	loss_cnaOV16, loss_cnaOV17	1175	AG-014699	PARP1, PARP2	6	27	1.6094379124341	NA	4.56132464503213	3.75445421854514	0.806870426486997	0.721996626262743	1.08461550060702	0.779766002781352	1.11755428922651	0.74392300869333	0.135097278170573	NA	NA	0.301340747468712	0.047725597974909	67.8001714431587
a1881	loss_cnaOV38	305	TPCA-1	IKK	8	24	2.99573227355399	NA	2.76743429854466	3.51111524906352	-0.743680950518852	0.970796336097108	1.25565882775341	0.622182029457656	0.766052489967847	0.592263546499672	0.135285105689991	NA	NA	0.993398662922464	0.102361350937914	67.8001714431587
a1882	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1264	SGC0946	Q8TEK3 (DOT1L)	8	25	-0.693147180559945	NA	2.37280184619533	2.0329154532827	0.339886392912629	0.471049194248798	0.562524463330954	0.625691884128475	0.721551797694208	0.604216198705408	0.135288434455132	NA	NA	0.0365186073446918	0.112946246484238	67.8001714431587
a1883	loss_cnaOV56	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.53333975902784	3.86494350680209	0.668396252225753	0.621643089185045	0.713324141325751	0.944620551188861	1.07520901278256	0.937016166288026	0.135333678147778	NA	NA	0.954317370386584	0.19370817911424	67.8001714431587
a1884	gain_cnaOV72_(ASXL1)	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.227884770348173	0.980342391756088	-0.752457621407915	0.71016415803068	1.09882680714466	0.728517435212478	1.05955448877414	0.684782730558968	0.1353562760468	NA	NA	0.322991553185647	0.146648638285502	67.8001714431587
a1885	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.01886977423155	-4.21398080421826	1.1951110299867	1.7351847085268	1.44838784018636	0.807161209618973	0.68875147649346	0.825131913447251	0.135368725104463	NA	NA	0.859441686027795	0.266162809889617	67.8001714431587
a1886	loss_cnaOV20	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.38435086323783	5.86916379208781	0.515187071150017	0.711246091711344	0.6777435023627	0.755230321964058	0.724344326322292	0.760150513216297	0.135452467382823	NA	NA	0.905777377788877	0.189222521678095	67.8001714431587
a1887	gain_cnaOV26	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.95458098483709	4.85872215353352	1.09585883130357	0.450862025020399	1.18625946682338	0.974117090867277	2.43058579008509	0.923793539231442	0.135559412502472	NA	NA	0.788714867115899	0.0223724014796154	67.8001714431587
a1888	loss_cnaOV43_(NF1)	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.78226629708627	0.676300518514582	1.10596577857168	0.564052243420155	1.36874040281228	0.855113889118209	1.96075060683318	0.808017193252506	0.135634231272881	NA	NA	0.150638424356709	0.00819994872687434	67.8001714431587
a1889	loss_cnaOV58	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.62991460054744	3.77102281314908	0.858891787398354	0.80223614395986	1.06605230749388	0.829210897590368	1.07062215267295	0.805675088699422	0.135715026985578	NA	NA	0.301397448964106	0.0763088365145047	67.8001714431587
a1890	gain_cnaOV49	1262	UNC1215	LMBL3	3	30	0	NA	2.44779989127363	2.81367398586612	-0.365874094592488	0.238986057398595	0.499435564732137	0.751504865415074	1.5309432632811	0.732575171711526	0.135835066711638	NA	NA	0.0992397604575379	0.0901565529992104	67.8001714431587
a1891	loss_cnaOV85	154	CHIR-99021	GSK3B	6	13	0.940007258491471	NA	3.8871765977809	3.05757130012007	0.829605297660826	0.905270800545726	0.902815173546101	0.918174107845913	0.916416719903827	0.91890934265347	0.135939276820923	NA	NA	0.16532652262996	0.093413965994144	67.8001714431587
a1892	loss_cnaOV41	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.05784120668659	3.06226399107774	-1.00442278439115	0.546291954551143	1.2713937016221	0.836813390965593	1.83861903149649	0.790017115162408	0.135953778026217	NA	NA	0.216858199957652	0.0116018391486331	67.8001714431587
a1893	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	2.48869943901119	3.39232055809661	-0.903621119085418	0.85328396867698	1.06828227631097	0.867047633877489	1.05899226079037	0.845863625301199	0.136007313228793	NA	NA	0.054650654907838	0.0781412145242339	67.8001714431587
a1894	loss_cnaOV59	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.87872224625756	2.2073578308775	0.671364415380062	0.992049624858773	0.863826320877238	0.764687098993771	0.676744790338121	0.777198377908043	0.136055888339062	NA	NA	0.58184818223924	0.273735770110979	67.8001714431587
a1895	PIK3R1_mut	192	LFM-A13	BTK	3	16	2.77258872223978	NA	4.1897544840648	4.82545978437364	-0.635705300308839	1.09606956116447	0.571802438484272	0.969633357917399	0.579986273529449	1.11175688930946	0.136140575300009	NA	NA	0.954249022084201	0.422000172828778	67.8001714431587
a1896	loss_cnaOV36	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.05862958535407	4.53565294459769	-0.477023359243613	0.602722628627251	0.670980710750543	0.715716412794115	0.791447569058543	0.710934534481663	0.136235986022165	NA	NA	0.0462168824768914	0.301725465239633	67.8001714431587
a1897	ARID1A_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	9	22	2.30258509299405	NA	0.753754347407688	1.67709022053542	-0.923335873127728	0.970451275042183	1.55055819547823	0.652767357971757	0.951450007716866	0.595486113207735	0.136261522582557	NA	NA	0.461575095230881	0.0575516256919611	67.8001714431587
a1898	gain_cnaOV94	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	3.35896160813284	2.11693394507817	1.24202766305467	2.09160807657133	0.956840138313878	1.08001698253065	0.593814719385985	1.29805138112552	0.136389566432601	NA	NA	0.361280525167948	0.412448961269014	67.8001714431587
a1899	PTEN_mut	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	10.0134843868455	8.62293976920897	1.39054461763649	1.57455254852887	1.6771138869586	0.83254035967664	0.883136367176634	0.829129511388286	0.136390167866193	NA	NA	0.919118994486563	0.260822302441494	67.8001714431587
a1900	gain_cnaOV18_(CCNE1)	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	6.28062459171233	5.43276311406575	0.847861477646577	0.327706823201059	0.990296084155776	0.897041243522774	2.58725610093992	0.85616967613214	0.136409537992554	NA	NA	0.288757487998836	0.00448485398543361	67.8001714431587
a1901	gain_cnaOV96	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-2.3432277454072	-3.75337722508154	1.41014947967434	1.68073677927556	1.6875797329895	0.836202015096229	0.839006736249413	0.83560465446945	0.136474169168403	NA	NA	0.662976282672666	0.19940773686666	67.8001714431587
a1902	loss_cnaOV59	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	4.33142241989391	3.27827358826391	1.05314883163	1.4105835582409	1.14893865925271	0.894225471999978	0.746605066730931	0.916627552871259	0.13650389421658	NA	NA	0.311273670867397	0.234378564406582	67.8001714431587
a1903	gain_cnaOV96	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.793050761445952	-0.245288567958535	1.03833932940449	1.24926400928461	1.21470872436524	0.852265232886213	0.831160844855435	0.854805196156866	0.136510983217697	NA	NA	0.75940369191023	0.196469090035718	67.8001714431587
a1904	gain_cnaOV18_(CCNE1)	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.35969918883415	-4.78666882083157	1.42696963199742	1.73651608381564	1.33345486055312	1.04533901129501	0.821742824783951	1.07012968658385	0.136525482024331	NA	NA	0.123051762138289	0.288134230896155	67.8001714431587
a1905	gain_cnaOV19	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.35969918883415	-4.78666882083157	1.42696963199742	1.73651608381564	1.33345486055312	1.04533901129501	0.821742824783951	1.07012968658385	0.136525482024331	NA	NA	0.123051762138289	0.288134230896155	67.8001714431587
a1906	gain_cnaOV72_(ASXL1)	1248	FK866	NAMPT	5	27	0	NA	-0.232250649025767	-1.98171091594313	1.74946026691736	1.73015645583074	2.82195592428305	0.647470175371608	1.01115726327614	0.619945992729081	0.136562811969064	NA	NA	0.038417245219418	0.098821051282119	67.8001714431587
a1907	loss_cnaOV40	207	AS601245	JNK 	4	14	2.07944154167984	NA	2.57535836011079	1.82721689311417	0.748141466996622	1.09269131771214	0.910198433697227	0.789930240464149	0.684677781244816	0.821954245688679	0.136607263793854	NA	NA	0.45137208508401	0.27513012088065	67.8001714431587
a1908	TP53_mut	279	BIX02189	MAP2K5 (MEK5)	22	10	2.99573227355399	NA	4.30241746096114	4.71446725429298	-0.412049793331831	0.770018351359174	0.57579695071935	0.574449384697165	0.535116848325127	0.715616490877648	0.136644278859722	NA	NA	0.510841069919025	0.106321855855977	67.8001714431587
a1909	loss_cnaOV38	274	PXD101, Belinostat	HDAC	8	22	2.99573227355399	NA	-0.180829330727119	1.23134035120448	-1.4121696819316	1.28865258283692	2.17672187295028	0.708859702453077	1.09584980524601	0.648759816070383	0.136662208404365	NA	NA	0.399781642897009	0.0412875027400816	67.8001714431587
a1910	loss_cnaOV41	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	2.489734716627	3.3921288400196	-0.902394123392606	0.852134873854839	1.06859163165827	0.865746114927768	1.05898039275216	0.844470513017446	0.136680521853762	NA	NA	0.0546810032492047	0.0781713412477067	67.8001714431587
a1911	gain_cnaOV95_(MECOM)	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	3.171648185954	4.04311521398069	-0.871467028026695	2.26985704958104	1.3044225939105	0.588281423558292	0.383930357282873	0.668086425438358	0.13669239234552	NA	NA	0.0580869268440782	0.505405584571819	67.8001714431587
a1912	NF1_mut	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	3.4694222256612	2.69163708423227	0.777785141428932	1.21238142736719	1.20981473439683	0.642759577314732	0.641535018494941	0.642896072692242	0.136707220087187	NA	NA	0.0848608210063783	0.297653325844595	67.8001714431587
a1913	loss_cnaOV36	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.12734482656562	4.4259663171891	0.701378509376513	0.877104544872536	0.658222043054497	1.03986433383953	0.799652120692681	1.06556520976075	0.1368614833732	NA	NA	0.0726638291067258	0.298288239491906	67.8001714431587
a1914	gain_cnaOV72_(ASXL1)	1262	UNC1215	LMBL3	5	28	0	NA	3.05580415592137	2.73123565964991	0.324568496271459	0.126910269757867	0.516455537889335	0.670406861158693	2.55746439504624	0.628453898660694	0.136880481438184	NA	NA	0.0993045277474746	0.00774738211372758	67.8001714431587
a1915	loss_cnaOV56	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.99157518734035	2.52146338670569	1.47011180063465	1.90805899208118	1.64215915657625	0.885289900657465	0.770475025529035	0.895231010190084	0.136898455346371	NA	NA	0.629461520541999	0.311889159681399	67.8001714431587
a1916	PIK3CA_mut	235	QL-XII-47	BTK, BMX	6	26	2.32630161961136	NA	0.27776466634789	1.86240981859472	-1.58464515224683	0.896109229949456	1.5988392200376	1.05314139977878	1.76836160066805	0.991122266946622	0.136910961419223	NA	NA	0.0699272202801789	0.00557610389766195	67.8001714431587
a1917	loss_cnaOV81_(RB1)	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.89262586016895	0.699215260798754	1.19341059937019	0.586520327862031	1.34968969950959	0.921102779960006	2.03473015798171	0.884211089262826	0.137043319182838	NA	NA	0.150745032400808	0.0137658059740554	67.8035163570286
a1918	gain_cnaOV49	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	-0.134396565080955	0.973078431468954	-1.10747499654991	0.715798388857103	1.23942474249197	0.914076924981963	1.54718844550375	0.893539525702249	0.137060636277691	NA	NA	0.839852189229196	0.0906122514137847	67.8035163570286
a1919	SMAD4_mut	155	AP-24534	ABL	3	16	-0.669430653942629	NA	1.7259679604443	0.61278513078197	1.11318282966233	1.49168603887817	1.15674329724436	0.926874981549097	0.746258127145509	0.962342148265906	0.13732015498731	NA	NA	0.561561125171653	0.324297429458109	67.8371449390548
a1920	loss_cnaOV102	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	5.1506520335959	3.6074053632608	1.5432466703351	1.14307639717542	1.5268809061406	1.02536147854087	1.35008182668151	1.01071842874496	0.137430426815971	NA	NA	0.152582527409798	0.127644984778369	67.8371449390548
a1921	TP53_mut	1264	SGC0946	Q8TEK3 (DOT1L)	23	10	-0.693147180559945	NA	2.19287182192249	1.9369249197413	0.255946902181181	0.54915597966286	0.553433011760344	0.465018859335408	0.466073231758877	0.462471332107698	0.137496270994803	NA	NA	0.0365924215868179	0.237650621068336	67.8371449390548
a1922	loss_cnaOV44	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	4.46311027296589	2.67667411830356	1.78643615466233	1.10160232868675	1.82845559333564	0.998450312323098	1.62167064115777	0.977019163699431	0.137510802301379	NA	NA	0.330954629609489	0.0821337192941342	67.8371449390548
a1923	RB1_mut	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	2.80102458610923	3.77253050930464	-0.971505923195413	1.43599540940461	0.984226441298243	0.951910829110178	0.676538320967345	0.987075618405404	0.137542707426778	NA	NA	0.825521363949562	0.361734476953416	67.8371449390548
a1924	gain_cnaOV48_(SOX17)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	1.0814023080957	2.42372871575696	-1.34232640766126	1.00528688347725	1.38543785677676	0.985099922701877	1.33526700658642	0.968882437487453	0.137557588154681	NA	NA	0.516102466082878	0.129092967202958	67.8371449390548
a1925	loss_cnaOV52, loss_cnaOV53	258	STF-62247	stimulates autophagy	8	23	2.32630161961136	NA	4.86216964547621	4.35986148004294	0.502308165433267	0.38446866957676	0.706033479222657	0.780826014999483	1.30649960629102	0.711450915877684	0.137699865568105	NA	NA	0.0462777865938264	0.0196985939065314	67.8720331625976
a1926	loss_cnaOV1	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	3.94803286501837	4.45685190215982	-0.508819037141457	0.96059757298089	0.586514076923125	0.822623422844091	0.529690113168316	0.867530818374798	0.137801984809381	NA	NA	0.256058108418261	0.456985338040414	67.8721292935181
a1927	SMAD4_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.306038024659526	1.45066844036859	-1.14463041570906	1.63712392677536	1.29099682927403	0.868598745244283	0.699171514745156	0.886625272621878	0.137843125598079	NA	NA	0.568120997762443	0.349093067680746	67.8721292935181
a1928	loss_cnaOV58	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	5.22590149406447	4.40548422861355	0.820417265450922	0.769803065539969	1.00657952874782	0.838592998522786	1.06574954319706	0.815054590342721	0.138091731471204	NA	NA	0.177635183865045	0.0774382409027377	67.9381700678681
a1929	loss_cnaOV102	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.35651273585722	4.50898110233701	0.847531633520209	1.06846416865237	0.905685773197355	0.923803997908934	0.793224198233231	0.935789937969497	0.138173351797967	NA	NA	0.941283410218857	0.300963861345521	67.9381700678681
a1930	loss_cnaOV44	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.98063862458231	1.54943267682639	1.43120594775591	0.785591511540428	1.46835300415284	0.99875344887198	1.82181951654433	0.974701549088082	0.138192055685433	NA	NA	0.311118231566643	0.0590255775264681	67.9381700678681
a1931	loss_cnaOV44	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	1.30336100296086	-0.314327933075685	1.61768893603654	2.01522154508037	1.50424390515718	1.04710266410792	0.802735034262462	1.07541664652284	0.138275382328889	NA	NA	0.0900689941216376	0.296798048051931	67.9439311184977
a1932	TP53_mut	277	ABT-869	VEGFR and PDGFR family	22	10	0.0237165266173161	NA	2.80885917761432	2.51182458172021	0.29703459589411	0.61587073266829	0.382535526802691	0.534000217442396	0.482300229801785	0.77648891431545	0.138495523413293	NA	NA	0.123757869575084	0.107825808942157	68.0168774822407
a1933	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.48056889022172	1.42552471477642	1.0550441754453	2.31311844898703	0.764309399030905	1.03549887688419	0.456113337346529	1.38038885402041	0.13866661147681	NA	NA	0.433025584449821	0.513047328193936	68.0197582682808
a1934	loss_cnaOV56	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.40800680665895	4.7500850738923	0.657921732766646	0.435013415398218	0.74339130937668	0.905088465639309	1.51241711054905	0.885027474047688	0.138694066160896	NA	NA	0.75779593433368	0.0957451646146481	68.0197582682808
a1935	loss_cnaOV81_(RB1)	304	SB52334	ALK5	4	28	2.99573227355399	NA	5.02709732415569	4.2722894981128	0.754807826042892	1.37483963910418	0.995534310377186	0.725978780619314	0.54901517571512	0.758193683708312	0.138716453520109	NA	NA	0.336568515179013	0.35775282863695	68.0197582682808
a1936	loss_cnaOV81_(RB1)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-1.03561722264242	-2.47241147135056	1.43679424870814	0.737227341296928	1.61853938222992	0.923844859070588	1.94891611884678	0.887710403888114	0.139115146695263	NA	NA	0.113380067954413	0.0166841345770443	68.1800227304231
a1937	loss_cnaOV58	1030	KU-55933	ATM	5	28	2.30258509299405	NA	4.82179705817939	4.03120861737201	0.790588440807386	0.97138078091862	0.999802827952652	0.793619245495071	0.813881081793422	0.790744353490492	0.139208102585115	NA	NA	0.516927757093497	0.149461357896993	68.1862870220082
a1938	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	3.39736121269204	1.34222649754531	2.05513471514672	3.62402116099564	1.95250039444386	0.927575303307121	0.567086841894188	1.05256558257039	0.139480363437947	NA	NA	0.592207829842025	0.430941672264496	68.1862870220082
a1939	RB1_mut	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	3.10640353640867	2.28453561482277	0.821867921585898	1.04513546511923	0.825877229379974	0.975774903797576	0.786374540923401	0.995145394918945	0.13959541071595	NA	NA	0.596380790589002	0.304337566354691	68.1862870220082
a1940	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	226	GSK1070916	AURKB	7	25	0.940007258491471	2.32630161961136	3.03953570549007	2.11081145076719	0.92872425472288	0.741685712703554	1.52198976635824	0.662836669018589	1.25218032222509	0.610204007445527	0.139623711905593	NA	NA	0.815242415156495	0.0356411183863564	68.1862870220082
a1941	loss_cnaOV52, loss_cnaOV53	271	VNLG/124	HDAC, RAR 	8	23	1.63315443905142	NA	4.63169800659925	4.22419183960816	0.407506166991088	0.522829925800572	0.575136704591474	0.723868486449414	0.779423951999502	0.708537924527951	0.139633010889711	NA	NA	0.238771224146254	0.086608451969719	68.1862870220082
a1942	gain_cnaOV95_(MECOM)	1049	PD-173074	FGFR1, FGFR3	8	25	0.693147180559945	NA	3.45017696375034	2.83813646236446	0.612040501385872	0.823166985829445	1.01821827056794	0.62607580310676	0.743519251770239	0.601089686835504	0.139642194878391	NA	NA	0.0786762705243005	0.106102307742102	68.1862870220082
a1943	loss_cnaOV39	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	7	16	2.30258509299405	NA	2.11572375701313	1.32138341669385	0.794340340319277	1.50373877948638	0.733215082570115	0.782660610708598	0.528243569398797	1.08336606706848	0.139735973158875	NA	NA	0.433162838810294	0.223622745319018	68.1862870220082
a1944	loss_cnaOV40	206	Ruxolitinib	JAK1, JAK2, TYK2	7	25	1.65632149833295	0.0237165266173161	4.7552504489144	4.36700550750516	0.388244941409241	0.648376496049162	0.504004619631007	0.724338911726825	0.598795520465323	0.770320203996311	0.140024038884688	NA	NA	0.349765634635564	0.180388567649188	68.1862870220082
a1945	loss_cnaOV34	1001	AICAR	AAPK1 (AMPK) agonist	5	26	7.60090245954208	NA	8.07376883758822	8.87954589328425	-0.80577705569603	0.924334731049887	1.24668080932503	0.667394848388621	0.871737292377627	0.64633789954005	0.140077388301039	NA	NA	0.516313843010443	0.136401865009435	68.1862870220082
a1946	NF1_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-3.5016963661201	-2.13226262397432	-1.36943374214578	1.64134183869024	1.55338019925776	0.876656911978564	0.834337923926048	0.881583106827376	0.140115241733476	NA	NA	0.113444697521471	0.194612878714415	68.1862870220082
a1947	gain_cnaOV49	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	4.26487819175632	5.00494153475739	-0.740063343001062	1.02798763527763	0.777245723673521	0.929949472198333	0.719914634772032	0.952161357032983	0.140136253320278	NA	NA	0.944293115902005	0.337801539412718	68.1862870220082
a1948	loss_cnaOV43_(NF1)	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.78059289366285	3.95502762416337	0.825565269499482	1.18766398392238	1.06982526806903	0.759995917475811	0.69511686863903	0.771682343033062	0.140263100030171	NA	NA	0.813914686550356	0.204001981773871	68.1862870220082
a1949	loss_cnaOV56	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.66780499045599	5.08809093436722	0.579714056088763	0.856342479460779	0.538506820926014	1.02552850533177	0.676965197912168	1.07652128731051	0.140337400379548	NA	NA	0.00965242553732839	0.361461725992022	68.1862870220082
a1950	loss_cnaOV33_(ZFHX3)	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	2.4071127723409	3.37170361336788	-0.964590841026983	0.640460073491818	1.08084202173891	0.922888045511922	1.50609051360218	0.892443873966983	0.140348272183665	NA	NA	0.0548436385550619	0.0452285148654387	68.1862870220082
a1951	loss_cnaOV40	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	4.2111606800603	3.53313335070961	0.678027329350692	0.714620128214712	1.08465898296286	0.663800388234919	0.948794055164053	0.6251064528121	0.140379698187567	NA	NA	0.82561592915905	0.0695826986657283	68.1862870220082
a1952	loss_cnaOV70	333	T0901317	LXR	3	29	2.32630161961136	NA	4.15716964888753	4.8150257620149	-0.657856113127379	0.478560492175942	1.14317968732483	0.591966001000433	1.37465612787258	0.575461688500464	0.140395668591993	NA	NA	0.00399529132549577	0.118413885357478	68.1862870220082
a1953	loss_cnaOV102	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	2.3581950569529	1.04884176479257	1.30935329216033	1.69105675939556	1.43613180654779	0.900562657772006	0.774281102562363	0.911722229248434	0.140404178246323	NA	NA	0.807367540375857	0.310048139782242	68.1862870220082
a1954	loss_cnaOV81_(RB1)	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	2.82195498825284	1.34663800761465	1.47531698063818	1.6701925963614	1.88857712699491	0.789831611645229	0.883321470740703	0.781179100154463	0.140421473202511	NA	NA	0.775775354903181	0.176517041975884	68.1862870220082
a1955	gain_cnaOV51_(MYC)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	8	25	-2.30258509299405	NA	0.280970757595582	-0.528898624075441	0.809869381671023	0.606445261395431	1.52541411523913	0.589951060495997	1.33543690292429	0.530917718395483	0.140661828762046	NA	NA	0.885540869099006	0.0381364989086431	68.2077636191348
a1956	loss_cnaOV43_(NF1)	341	EX-527	SIRT1	5	26	2.99573227355399	NA	6.16163898747966	5.69863521954561	0.463003767934047	0.451785064998643	0.554471784640032	0.855091179203606	1.02483194732309	0.83503575972695	0.140711392275608	NA	NA	0.0997557374721745	0.086082443297069	68.2077636191348
a1957	loss_cnaOV59	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-1.46392298240399	-2.91336296367718	1.44943998127319	1.27530165048256	1.75511690959204	0.846045794758488	1.13654677756023	0.825836713982833	0.140715609492544	NA	NA	0.687016508983681	0.102118923900522	68.2077636191348
a1958	loss_cnaOV44	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	0.350596230609165	-1.48995029149257	1.84054652210174	2.17562381912464	1.7746232030601	1.02018416477323	0.845985646012223	1.03714778378191	0.140753246613195	NA	NA	0.0657490207975656	0.277433761275224	68.2077636191348
a1959	gain_cnaOV72_(ASXL1)	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.2152896372435	-3.47813595615615	1.26284631891266	2.21553078411429	1.72889579156146	0.707318864926649	0.569997188920809	0.730435185901005	0.140864942394012	NA	NA	0.127218785071076	0.343195357903549	68.2270451215826
a1960	gain_cnaOV4_(KRAS)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	-1.38629436111989	0.693147180559945	-1.48182911451133	-2.29635381669015	0.814524702178822	1.1074920793788	1.29117400282608	0.647621101432754	0.735467744957324	0.630840382780336	0.141347080989481	NA	NA	0.596509359035109	0.124514446310916	68.2580603444541
a1961	gain_cnaOV72_(ASXL1)	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.5928128882525	2.97411436464057	0.618698523611933	0.660587287879588	0.927402790433384	0.689401049965879	0.9365886007251	0.667130323516505	0.141421278934291	NA	NA	0.224969346398611	0.113625760962659	68.2580603444541
a1962	gain_cnaOV19	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	4.56862564295957	3.6219091195106	0.946716523448977	1.11902543321541	0.888763933904269	1.02825586561673	0.84601877253914	1.0652058295054	0.141480636414033	NA	NA	0.795897558173073	0.276623733929403	68.2580603444541
a1963	gain_cnaOV18_(CCNE1)	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	5.21551276254245	3.74241118923797	1.47310157330448	1.09535754395963	1.56756364166037	0.956774264272516	1.34485911146359	0.939739564094617	0.14157053761282	NA	NA	0.706599325492882	0.126554928168702	68.2580603444541
a1964	loss_cnaOV44	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	5.02585749308484	3.85647006921037	1.16938742387447	0.797358323107646	1.14207107893516	1.04250986741654	1.46657705825013	1.02391825293815	0.141591583530939	NA	NA	0.0736424139043702	0.106023110651773	68.2580603444541
a1965	loss_cnaOV36	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.59968040721335	4.87146131321168	0.728219094001665	0.83069043733125	0.794378301148445	0.913962895093798	0.876643164860795	0.916715742296672	0.141608954805175	NA	NA	0.944308260029049	0.264050996416252	68.2580603444541
a1966	gain_cnaOV48_(SOX17)	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	3.81994137730602	4.60750887968863	-0.787567502382604	0.984280641119506	0.998736123512075	0.789320630715501	0.800145273086786	0.7885641500711	0.141640148917106	NA	NA	0.17792290502256	0.297462855594014	68.2580603444541
a1967	gain_cnaOV48_(SOX17)	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.39785608162348	5.81354080002549	-0.41568471840201	0.562896598027715	0.554425755875021	0.748962443450573	0.738474383853965	0.749757228983629	0.141731284842614	NA	NA	0.0998208694326268	0.328199394973198	68.2580603444541
a1968	loss_cnaOV16, loss_cnaOV17	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	3.38759910391962	1.34405689294014	2.04354221097947	3.63271881984441	1.95239457670256	0.921680450597733	0.562537953616514	1.04668504787124	0.141764263072124	NA	NA	0.592502995678492	0.434092946483523	68.2580603444541
a1969	loss_cnaOV70	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	2.67097909409391	1.27381559629167	1.39716349780224	1.51090428212455	1.40913990168501	0.986423689058529	0.924720059590821	0.991500912103584	0.141776948827888	NA	NA	0.4620676773869	0.245206368817654	68.2580603444541
a1970	loss_cnaOV56	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	2.67085851749556	1.27382851521292	1.39703000228264	2.94417436734707	1.22992894886479	0.986320871064383	0.474506543422383	1.13586236308373	0.141819388696646	NA	NA	0.462071382930098	0.498312048434372	68.2580603444541
a1971	gain_cnaOV48_(SOX17)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	-0.122573652142376	0.97185537150979	-1.09442902365217	0.735732912490586	1.23971613935499	0.90250924107159	1.48753576885303	0.882806143204347	0.141842365103942	NA	NA	0.839998292262085	0.0996853969592066	68.2580603444541
a1972	loss_cnaOV59	309	Y-39983	ROCK	4	28	2.99573227355399	NA	5.88157357175531	4.83324902826972	1.04832454348559	0.563013540514173	1.2455895466408	0.877253684166931	1.8619881548998	0.841629207882155	0.141986884516528	NA	NA	0.357713894813106	0.0206846438708111	68.2580603444541
a1973	PIK3R1_mut	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	4.68581154944294	3.77255868090867	0.913252868534269	1.3693547831543	1.14888187504843	0.772803591616429	0.666922027635965	0.794905802213803	0.142089506539879	NA	NA	0.689311165256174	0.218998027051429	68.2580603444541
a1974	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1017	Olaparib	PARP1, PARP2	8	23	1.6094379124341	NA	4.50684543345143	3.78278134563188	0.724064087819548	1.2877058691156	1.07607604640047	0.640316311012087	0.562289964801384	0.672874459236945	0.142116962483596	NA	NA	0.0736705548031943	0.182453891463596	68.2580603444541
a1975	loss_cnaOV44	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	4.59819901650423	2.37920436160156	2.21899465490266	2.08604181485743	2.26855951442919	0.983226060287162	1.06373450383319	0.978151395539209	0.142159751769794	NA	NA	0.371182702305299	0.197688340771393	68.2580603444541
a1976	loss_cnaOV20	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	0.0165282458457205	-1.25866756404912	1.27519580989484	1.88746957438938	1.93788150184219	0.660300370696227	0.675611319619488	0.658036009261977	0.142281911727728	NA	NA	0.429327047336369	0.218898679919224	68.2580603444541
a1977	loss_cnaOV57_(ZNRF3)	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.95228201283227	4.08913806409857	0.863143948733698	1.27907302929569	0.890376911519891	0.921636118724272	0.674819911736378	0.969414118410027	0.142342666846254	NA	NA	0.0418590764573942	0.27252288837698	68.2580603444541
a1978	loss_cnaOV83	1020	Lenalidomide	TNFA	5	26	1.6094379124341	NA	4.95133739604576	4.29388399706689	0.657453398978867	0.521133231255575	0.766101027747261	0.891863560199663	1.26158410085431	0.858181069032273	0.142448598170234	NA	NA	0.0370839519876733	0.045952176605465	68.2580603444541
a1979	loss_cnaOV1	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.25200083895502	-2.88530525502455	1.63330441606953	1.69587386095411	1.71546811998466	0.952825889738644	0.963104894576666	0.95210420819953	0.142451028092661	NA	NA	0.687114129639356	0.230837092479268	68.2580603444541
a1980	loss_cnaOV102	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	5.31825773774028	4.35441400095598	0.963843736784306	1.10642999341474	0.967297249972859	0.986663556251898	0.871129436585158	0.996429729135848	0.142495898694986	NA	NA	0.360606538947181	0.266712931192368	68.2580603444541
a1981	loss_cnaOV55	1011	ABT-263	BCL2, BCL2L1, BCL2L2	8	25	0.693147180559945	NA	0.846853665164394	2.02288758758308	-1.17603392241868	0.945766582409494	1.78545477085965	0.719722416968568	1.24347163908302	0.658674720644115	0.142511641318338	NA	NA	0.215597613009063	0.0245750346607197	68.2580603444541
a1982	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.47188315658896	3.88872718814306	0.583155968445906	0.87964669625362	0.711347412275532	0.792316196534057	0.662943396399422	0.819790665408406	0.142590590430441	NA	NA	0.512567809201405	0.22021484195171	68.2614161308225
a1983	loss_cnaOV82	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	4.37117913873823	2.86901126677381	1.50216787196442	0.742329326669488	1.61541136231253	0.955357873340562	2.0235868609745	0.929898047648994	0.14270186876609	NA	NA	0.65346420484697	0.0409493034376701	68.2802374755461
a1984	loss_cnaOV16, loss_cnaOV17	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.74899068052966	2.5139687773588	1.23502190317087	1.88761006268514	1.15522666728309	0.977370465048198	0.654278088247757	1.069073228785	0.143001323808143	NA	NA	0.937646508346686	0.375083396969127	68.3890335811189
a1985	loss_cnaOV16, loss_cnaOV17	1114	Cetuximab	EGFR	5	27	4.18661983833127	NA	6.53253378551471	5.69087545438732	0.841658331127397	0.442543876278405	1.34036345745241	0.668922285691333	1.90186414555177	0.627932913604725	0.143536422254824	NA	NA	0.55889549447856	0.0174742872295046	68.610357529988
a1986	loss_cnaOV40	262	VX-11e	ERK	7	25	1.63315443905142	NA	2.25613570583857	3.02815731410617	-0.772021608267604	0.886233060162581	1.12373530180935	0.71455716760247	0.87112706913233	0.687013754061617	0.143642283103657	NA	NA	0.37614746049422	0.0797607101332038	68.6263864902553
a1987	PIK3R1_mut	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	3.15124334004223	4.03507125252501	-0.883827912482787	0.349226083807227	1.09859771454939	0.855660151494426	2.53081872593073	0.804505508046958	0.143741697742893	NA	NA	0.302108984864674	0.00269368212003977	68.6265834646105
a1988	loss_cnaOV55	1021	Axitinib	PDGFR, KIT, VEGFR	7	23	0.693147180559945	NA	3.11614512723378	2.34545090898065	0.770694218253131	0.642323212219995	1.06754340239316	0.776994677277404	1.19985422228392	0.721932444643875	0.143831883645385	NA	NA	0.181359961694143	0.0317168062207184	68.6265834646105
a1989	loss_cnaOV59	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	2.13626671370906	1.53993244702805	0.596334266681005	1.10189387775636	0.589048985670785	0.905516006736083	0.541190289481633	1.01236786954471	0.143859678315362	NA	NA	0.195409463305135	0.361126840701485	68.6265834646105
a1990	loss_cnaOV87, loss_cnaOV88	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	4.09589426346223	2.90867630618824	1.18721795727399	1.04395785650049	1.15381012825907	1.03544993146847	1.13722785827172	1.02895435583091	0.144143876305096	NA	NA	0.0791169173248433	0.176884471800407	68.6679914755452
a1991	gain_cnaOV96	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.94770648666303	4.45451886527275	0.493187621390273	0.66891438457877	0.569418503590038	0.850123443615516	0.737295583351589	0.866125035067971	0.144318918079198	NA	NA	0.604001884390267	0.239521710738161	68.6679914755452
a1992	loss_cnaOV102	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	4.43839934898431	2.67923042078441	1.7591689281999	1.13581896091469	1.82952694393752	0.981867775625777	1.54881102423508	0.961543055722262	0.144369710969437	NA	NA	0.331578925838966	0.0920043517899512	68.6679914755452
a1993	gain_cnaOV18_(CCNE1)	304	SB52334	ALK5	4	28	2.99573227355399	NA	5.01713484698031	4.27371270913786	0.743422137842451	0.653473253841374	1.07511525224222	0.714370671464301	1.13764738414667	0.691481342388177	0.144416909280382	NA	NA	0.337084550010609	0.104308514510479	68.6679914755452
a1994	loss_cnaOV85	223	ZSTK474	PI3K	7	25	1.63315443905142	2.32630161961136	1.28651076092088	0.610355413812322	0.676155347108556	0.433682982210665	1.11545862232377	0.665262847574792	1.559100483173	0.606168022351167	0.144544402229931	NA	NA	0.764968295312942	0.021615869735095	68.6679914755452
a1995	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.88713100951313	2.89644780801916	0.990683201493965	0.802599806114892	0.981394338063237	1.02042516980442	1.23434268728461	1.00946496537677	0.144675049497301	NA	NA	0.0789380947209519	0.152555794194854	68.6679914755452
a1996	loss_cnaOV44	309	Y-39983	ROCK	3	29	2.99573227355399	NA	6.02524137711871	4.85453596369714	1.17070541342157	0.519746530160814	1.23087162313479	0.978291716219532	2.25245450519765	0.951119021202234	0.14477977477784	NA	NA	0.357962162526603	0.0276515272222681	68.6679914755452
a1997	loss_cnaOV54	197	Bryostatin 1	PRKC	6	13	-4.8283137373023	NA	-2.6691940679346	-2.16788384982097	-0.501310218113636	0.959584295929976	0.601402139355558	0.691129883573895	0.522424366717875	0.833569063540118	0.144786256525035	NA	NA	0.656492509941473	0.278142474896686	68.6679914755452
a1998	loss_cnaOV56	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	2.0566626538839	3.81073995689066	-1.75407730300676	5.02444553077634	1.54083593994856	0.888336792103495	0.349108631442509	1.13839329517801	0.144789777099092	NA	NA	0.739764153728484	0.60743748331016	68.6679914755452
a1999	TP53_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	22	10	1.65632149833295	0.0237165266173161	4.54548062577292	4.24613170630257	0.299348919470351	0.590213994512358	0.4098379880119	0.551860225283662	0.507187091891436	0.730407937347328	0.144802063022657	NA	NA	0.350194427051938	0.110189809648719	68.6679914755452
a2000	loss_cnaOV40	305	TPCA-1	IKK	7	25	2.99573227355399	NA	2.72836971059305	3.49230609566921	-0.763936385076163	0.891707675462502	1.2618883752617	0.638184828733777	0.8567116848915	0.60539141183366	0.144918839304066	NA	NA	0.99341090532373	0.0918208135796166	68.6679914755452
a2001	KRAS_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	7	26	0.693147180559945	NA	2.32666994932197	2.92472677228109	-0.598056822959123	0.752596841300179	0.975654233245792	0.638515209028471	0.794657630938134	0.61298029832712	0.1449515739055	NA	NA	0.965169333984041	0.106464276518485	68.6679914755452
a2002	loss_cnaOV59	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	0.282217437875654	1.34486515658712	-1.06264771871147	1.38747109217587	1.17410029678798	0.8881944852195	0.765888186574752	0.905074056806378	0.144953365216456	NA	NA	0.253014935664523	0.224932572446873	68.6679914755452
a2003	loss_cnaOV83	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.0317055490778037	-1.55549044503956	1.52378489596176	1.87993139013238	1.78589158165733	0.847152260295253	0.810553461663544	0.853234827697472	0.145029453540918	NA	NA	0.0659544190244182	0.149645475296934	68.6679914755452
a2004	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.88243872595715	3.83440664864134	1.04803207731581	0.711427650111894	1.15772978728624	0.935876937675818	1.47313936582444	0.905247570568634	0.145032049819161	NA	NA	0.0738247117602425	0.0486958899402435	68.6679914755452
a2005	TP53_mut	1017	Olaparib	PARP1, PARP2	21	10	1.6094379124341	NA	4.14220910071233	3.60723433021859	0.53497477049374	1.10022710289973	1.24922251788777	0.465787859620762	0.486240312644336	0.428246179390278	0.145231638205113	NA	NA	0.0738351455123286	0.264254369073295	68.6811828102622
a2006	loss_cnaOV85	193	GW-2580	CSF1R (cFMS)	7	25	2.99573227355399	NA	6.06389414153667	5.63199681527657	0.431897326260101	0.648809964064605	0.562539221184894	0.743600036507946	0.66567616125127	0.767763935375709	0.145252405602618	NA	NA	0.179180159026342	0.145070388018712	68.6811828102622
a2007	PTEN_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	4.37277581813861	3.39498604678587	0.977789771352738	1.11949840779772	1.08014834910564	0.902929633476135	0.873417741858381	0.905236555851192	0.145293803745079	NA	NA	0.718312073756142	0.265191497904278	68.6811828102622
a2008	gain_cnaOV19	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	6.38382009185757	5.45132432017647	0.932495771681104	0.311755954967072	0.977574986971044	0.983799627982978	2.99110813065173	0.95388669320436	0.145349451667348	NA	NA	0.289566984313826	0.00715107866431748	68.6811828102622
a2009	loss_cnaOV40	1069	EHT 1864	Rac GTPases	8	25	2.30258509299405	NA	4.74159559604835	4.06539770075018	0.676197895298174	0.986057371101117	0.925999214390556	0.719438878806959	0.685759181073889	0.730235927622478	0.145468460054356	NA	NA	0.196494118710656	0.114123972063016	68.7032024513506
a2010	loss_cnaOV55	1049	PD-173074	FGFR1, FGFR3	8	25	0.693147180559945	NA	3.53608920044153	2.81064454662328	0.725444653818253	0.701736769385785	1.02590159002546	0.753868540400914	1.03378458343179	0.707128891183652	0.145687718597403	NA	NA	0.0789895970832293	0.0373595198897084	68.7725237062468
a2011	loss_cnaOV40	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	3.03050232913329	2.28942015403206	0.741082175101232	0.952109208760428	0.764118841482878	0.925764845280504	0.778358373474891	0.969851984886355	0.145766152356023	NA	NA	0.601896155646318	0.222230769901642	68.7753321213377
a2012	loss_cnaOV87, loss_cnaOV88	293	MP470	PDGFR	3	29	2.99573227355399	NA	5.40672173125273	3.90881386508934	1.49790786616339	1.18043525682368	1.75575260521942	0.869166805448259	1.2689453805319	0.853142898213835	0.14594335297606	NA	NA	0.611430949840583	0.141415832271534	68.7827987336979
a2013	loss_cnaOV44	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.2152461165306	1.55232541455276	0.662920701977838	0.965392450368403	0.632365990327235	1.00470235058448	0.686685193907266	1.04831808180385	0.14604537203669	NA	NA	0.195585310706407	0.355970147562964	68.7827987336979
a2014	gain_cnaOV18_(CCNE1)	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	5.07364453299778	3.44238816355321	1.63125636944457	0.403665167979403	2.06854488636445	0.829505266073036	4.04111253296893	0.788600905011819	0.146089747393099	NA	NA	0.739824241191964	0.000978189696494442	68.7827987336979
a2015	loss_cnaOV41	290	KIN001-260	IKK	5	26	2.99573227355399	NA	4.3421938617309	4.94794883647817	-0.605754974747274	1.06140713143664	0.847245804082945	0.688444123053195	0.570709350640378	0.714969577692911	0.14613284164281	NA	NA	0.655265283796298	0.282017152448531	68.7827987336979
a2016	loss_cnaOV20	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.5241838942506	3.54688327380132	0.977300620449278	0.920122244677751	1.21386294461272	0.828167072965257	1.06214215133072	0.805116116927917	0.146262839544434	NA	NA	0.185373215637564	0.0780333991152224	68.7827987336979
a2017	loss_cnaOV39	279	BIX02189	MAP2K5 (MEK5)	9	23	2.99573227355399	NA	4.10235701124535	4.5598540688203	-0.457497057574946	0.688890638386568	0.721493081311218	0.641700453944787	0.664106945402012	0.634097636450658	0.146440659148681	NA	NA	0.511623422401177	0.115925655489571	68.7827987336979
a2018	TP53_mut	1028	VX-702	p38	21	10	0.693147180559945	NA	3.48506351501316	2.99497120553922	0.490092309473932	0.871004041171383	0.970362734678103	0.542731752474875	0.562675126988876	0.505060934390179	0.146590179704051	NA	NA	0.504787739536635	0.193192538438912	68.7827987336979
a2019	loss_cnaOV84	1067	CCT007093	PPM1D	6	27	1.88706964903238	NA	4.93445613589851	4.3908995251844	0.543556610714107	0.675316481555683	0.671222111679911	0.809003434913144	0.804891670142495	0.809801407396596	0.146624182608781	NA	NA	0.0731509035197761	0.115247298951014	68.7827987336979
a2020	PIK3R1_mut	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	2.41439884334289	3.18454544408872	-0.77014660074583	0.431632949773457	0.929555485253752	0.873915031650002	1.78426276573659	0.828510630041189	0.146669593282398	NA	NA	0.225397683520318	0.011998657359446	68.7827987336979
a2021	loss_cnaOV33_(ZFHX3)	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	4.29685215160556	2.34300410462628	1.95384804697928	1.39618383720076	2.3331660524765	0.865668260527689	1.39942033056091	0.837423485098889	0.146818184929526	NA	NA	0.371591534902796	0.0574758111106893	68.7827987336979
a2022	loss_cnaOV87, loss_cnaOV88	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	1.60204592410685	0.45466975046009	1.14737617364676	1.01060445356066	1.18234338503035	0.979568276961539	1.13533654992734	0.97042550258553	0.146959047238326	NA	NA	0.416411672003277	0.176593965041998	68.7827987336979
a2023	loss_cnaOV83	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	5.21310582879771	4.40785379625554	0.805252032542162	0.838082103698728	1.00015631912073	0.821605112558662	0.960827142100188	0.805126175926268	0.146997113841425	NA	NA	0.178342563853761	0.102072980052976	68.7827987336979
a2024	loss_cnaOV83	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	4.20845222082317	3.26204033506849	0.94641188575468	1.57835533889442	1.10504525105419	0.802600669177256	0.599619022683197	0.856446272088694	0.147034661832714	NA	NA	0.312225505163455	0.258232547441619	68.7827987336979
a2025	loss_cnaOV83	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.84188974310973	2.27264054531621	0.569249197793524	0.672532958402655	0.875803493112822	0.668518111066887	0.846425726325082	0.649973655357633	0.147101863525711	NA	NA	0.596895628648323	0.143941482457291	68.7827987336979
a2026	loss_cnaOV87, loss_cnaOV88	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	5.12196268777052	3.61027429784334	1.51168838992718	1.19089278722056	1.52732944810113	1.00251848730445	1.26937404118076	0.989759211286471	0.147102643817668	NA	NA	0.153284783421433	0.14419170421806	68.7827987336979
a2027	loss_cnaOV58	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	1.94530447490349	0.63665322824657	1.30865124665692	2.57047187493229	1.9285065308729	0.643809904845324	0.509109342692726	0.678582740430015	0.147270334745367	NA	NA	0.400788704734412	0.330311283494488	68.7827987336979
a2028	loss_cnaOV83	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.52235005610724	3.54721074489835	0.975139311208889	1.26491117081247	1.16726823694882	0.826164289463624	0.770915249789867	0.835402935111005	0.147343356163727	NA	NA	0.185454647817158	0.165966489849273	68.7827987336979
a2029	loss_cnaOV35	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	3.08392576382171	2.27058026609874	0.813345497722972	0.830126527181195	0.962795189125844	0.857822656124234	0.979784973845848	0.844775199241946	0.147387681171814	NA	NA	0.384265618844632	0.223521340935219	68.7827987336979
a2030	loss_cnaOV87, loss_cnaOV88	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.37079384803183	3.48028060107516	0.890513246956676	1.94853091557863	0.759883454432939	1.00501275628984	0.457017766480874	1.17190766789523	0.147464515888666	NA	NA	0.131760403462156	0.512252541401659	68.7827987336979
a2031	TP53_mut	1268	XAV 939	TNKS1 (tankyrase-1)	22	10	1.6094379124341	NA	3.05337393925946	2.42133786342277	0.632036075836688	0.992316307527842	1.13768895231761	0.608858114695965	0.636930050470782	0.555543828169512	0.147534027541731	NA	NA	0.29237289834357	0.150052338954055	68.7827987336979
a2032	SMAD4_mut	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	3.33479592246282	2.31177434260533	1.02302157985749	1.55954176746294	1.41278814024414	0.716330298457326	0.65597574954452	0.724115350855579	0.147630953662175	NA	NA	0.226249398304028	0.28670647445559	68.7827987336979
a2033	loss_cnaOV59	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	5.29582678733167	4.4247955176272	0.871031269704472	0.87036316291704	0.993034873280358	0.887487132355615	1.00076761841022	0.877140665591266	0.147641954071062	NA	NA	0.178391938538622	0.13646317792074	68.7827987336979
a2034	loss_cnaOV33_(ZFHX3)	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	4.9520894248667	5.62255385218656	-0.670464427319856	2.13414275590668	0.722129650909462	0.697198390609994	0.314161002334172	0.928454366159127	0.147693098086035	NA	NA	0.289769986070767	0.575991460523463	68.7827987336979
a2035	loss_cnaOV44	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.42292767436631	2.44845628924397	0.97447138512234	0.757618461111719	1.01760226916716	0.971687438437266	1.28622972530581	0.957615184879535	0.147875411129377	NA	NA	0.381378921893559	0.139861376431482	68.7827987336979
a2036	loss_cnaOV43_(NF1)	1033	Vismodegib	SMO	5	26	2.30258509299405	NA	5.49855686535059	4.79794071970931	0.700616145641275	0.787407974294096	0.831420275444688	0.848728486470002	0.889775273446235	0.842673875455525	0.147899364914232	NA	NA	0.141940097917274	0.122247253106978	68.7827987336979
a2037	TP53_mut	1001	AICAR	AAPK1 (AMPK) agonist	21	10	7.60090245954208	NA	8.9602143878324	8.30725352688512	0.652960860947282	1.19725705124227	1.22197281831808	0.5418844559682	0.545380676831072	0.534349742612127	0.147964039309566	NA	NA	0.516949096904032	0.179073294593454	68.7827987336979
a2038	loss_cnaOV83	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.6848469092447	1.85519528108716	0.829651628157539	1.14614366134997	0.915936712084578	0.875367334424331	0.723863557540721	0.905795801403502	0.14803046008791	NA	NA	0.453255465752613	0.336518096018581	68.7827987336979
a2039	loss_cnaOV56	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.94415120857476	0.812234315903258	1.1319168926715	0.329918814721401	1.2748215804178	0.919055240306393	3.43089524502366	0.887902205342754	0.148077426006875	NA	NA	0.956063624477092	0.00351256478903311	68.7827987336979
a2040	SMARCA4_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	4.56656907403666	5.20201189123819	-0.635442817201531	0.726844175480304	0.545947313215477	1.13506671608803	0.874249032513228	1.16392699775176	0.148079034809553	NA	NA	0.00974613241242502	0.266066113364382	68.7827987336979
a2041	NF1_mut	293	MP470	PDGFR	4	28	2.99573227355399	NA	5.30502108677423	3.86984581908043	1.4351752676938	0.474435112183966	1.79832594918254	0.837996943586705	3.02501908235094	0.7980618131803	0.148170403614093	NA	NA	0.61157498970364	0.00259966759572353	68.7827987336979
a2042	loss_cnaOV43_(NF1)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	2.30258509299405	NA	2.89068648891228	2.02755124308249	0.863135245829798	0.585393725032821	1.34919190305871	0.678875303502479	1.47445250763732	0.639742384958736	0.148304769324663	NA	NA	0.677112906587267	0.0360272273537298	68.7827987336979
a2043	loss_cnaOV20	1262	UNC1215	LMBL3	5	28	0	NA	3.12091654468916	2.71960844736995	0.401308097319212	0.553724758858311	0.463611960501448	0.842732658746876	0.72474291766661	0.865612045222372	0.148344758713795	NA	NA	0.0999816697825935	0.186509157148073	68.7827987336979
a2044	gain_cnaOV4_(KRAS)	253	XMD14-99	EPHB3, CAMK1	8	24	2.32630161961136	NA	5.12089544685188	4.7731200295549	0.347775417296974	0.616502486298092	0.602590166853028	0.574014749379348	0.564110324007384	0.577134238869511	0.148364902739897	NA	NA	0.0434616218352158	0.190316752457165	68.7827987336979
a2045	gain_cnaOV72_(ASXL1)	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.36911141247	5.87188512258207	0.497226289887936	0.401583901284182	0.716411517772935	0.726959821254029	1.23816290518099	0.694051222729686	0.148444477554186	NA	NA	0.906000652493029	0.0531775838748302	68.7827987336979
a2046	loss_cnaOV55	1054	PD-0332991	CDK4, CDK6	8	25	1.38629436111989	0.693147180559945	3.24753641322842	1.97587531504868	1.27166109817973	1.82542593931481	1.68195057555189	0.741321534764803	0.696638012417563	0.756063297378681	0.14859048489607	NA	NA	0.100794328283446	0.108205051769006	68.7827987336979
a2047	loss_cnaOV59	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.69917878119198	3.79108609124633	0.908092689945656	0.908915248761792	1.05240339947586	0.873683924499718	0.999095010434409	0.862875101313739	0.148668223637069	NA	NA	0.302523967244784	0.136939184491927	68.7827987336979
a2048	loss_cnaOV82	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	3.03101286858794	1.8264129652989	1.20459990328904	0.170139465791236	1.34847937498312	0.924130603241453	7.08007338383856	0.893302430601965	0.1487295307817	NA	NA	0.834183809443381	0.000115272283650137	68.7827987336979
a2049	TP53_mut	1066	AZD6482	PI3Kbeta	23	10	1.6094379124341	NA	2.56605302360569	1.94915307725327	0.616899946352421	1.28617885639436	1.28133703112359	0.480161837496018	0.47963776055363	0.4814501816212	0.148777761200383	NA	NA	0.100319434967826	0.221087532686318	68.7827987336979
a2050	gain_cnaOV19	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.51500892454781	5.89044379070015	0.624565133847661	0.501475900464354	0.694430115524466	0.913605242871816	1.24545393561152	0.8993923504829	0.148829888071247	NA	NA	0.906006928537272	0.147976529214449	68.7827987336979
a2051	loss_cnaOV42	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	5.22212530615299	4.49791031966903	0.724214986483953	0.943242028887871	0.916894561229357	0.787564056234654	0.767793381024209	0.789856344564786	0.148886487458332	NA	NA	0.941401036985305	0.225454327160713	68.7827987336979
a2052	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.27399201944456	-2.88303030531873	1.60903828587418	1.4910227447766	1.73121398222975	0.937532856853797	1.07915073161091	0.929427732441128	0.148918971958002	NA	NA	0.687466294650342	0.192425819177228	68.7827987336979
a2053	gain_cnaOV96	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.91305456978934	2.28280446999747	0.630250099791871	0.59879819568187	0.874603834339515	0.740551552917631	1.05252504823296	0.720612093208835	0.148952693694701	NA	NA	0.597017951475297	0.124050167395363	68.7827987336979
a2054	gain_cnaOV96	1030	KU-55933	ATM	4	29	2.30258509299405	NA	4.89369447170349	4.04855340312066	0.845141068582824	1.09002996874345	0.98814542847428	0.846444848829956	0.775337461186572	0.8552800470754	0.148971602911328	NA	NA	0.517660344315324	0.220889679474473	68.7827987336979
a2055	loss_cnaOV33_(ZFHX3)	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.78637471123977	5.72266145042454	1.06371326081523	0.570726696073504	1.29221762992004	0.846185948194121	1.86378746277927	0.823168819389234	0.148990039943942	NA	NA	0.559286489366588	0.0518275475755433	68.7827987336979
a2056	gain_cnaOV96	185	OSI-906	IGF1R	4	14	0.940007258491471	NA	2.99637170294811	1.9828758901127	1.0134958128354	0.815182902702661	1.3275357441595	0.812355684431117	1.24327412838917	0.763441449538577	0.149044130151506	NA	NA	0.667906766548619	0.0967443239913489	68.7827987336979
a2057	loss_cnaOV39	1036	PLX4720	BRAF	10	23	2.30258509299405	NA	4.87584114932836	4.06095556521293	0.814885584115429	1.23131873998798	1.27549136018231	0.645287182733729	0.661799059537895	0.638879736511077	0.149146948685584	NA	NA	0.35731017119683	0.101295701587893	68.7855212754162
a2058	loss_cnaOV59	293	MP470	PDGFR	4	28	2.99573227355399	NA	5.18279598802446	3.88730654747325	1.29548944055121	1.14735499577671	1.77824691604127	0.7507607467689	1.12910951302758	0.728520560820216	0.149195019876192	NA	NA	0.611640426537916	0.105188090900509	68.7855212754162
a2059	TP53_mut	1006	Cytarabine	DNA synthesis	21	10	0.693147180559945	NA	0.11011913645895	-0.576309015473458	0.686428151932408	1.18395065993097	1.31550114340144	0.559761045784896	0.579777667400795	0.521799737974789	0.149328100831304	NA	NA	0.759985800306214	0.179864933269265	68.7918247572142
a2060	loss_cnaOV44	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-1.70672650752114	-3.48752320866524	1.7807967011441	2.55747111481241	1.68130782089509	1.01422170922528	0.69631155981784	1.05917350708334	0.149407995812522	NA	NA	0.127817364213163	0.350612860503248	68.7918247572142
a2061	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	163	JQ1	BRD4	3	16	0.940007258491471	NA	1.43545376073757	-0.164040639776762	1.59949440051433	2.29801405796374	1.70627878936803	0.895523907972694	0.696033340166611	0.937416798755815	0.149510905218544	NA	NA	0.560849016984436	0.351415259882327	68.7918247572142
a2062	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-0.509842592826463	-1.77147649360329	1.26163390077683	1.93411504819579	1.11263360194164	1.01916946430332	0.65230550889603	1.13391677060191	0.149568064453166	NA	NA	0.602463826264622	0.376116691893192	68.7918247572142
a2063	SMARCA4_mut	1061	SB590885	BRAF	3	30	1.6094379124341	NA	2.97786456930187	4.02250734975165	-1.04464278044978	1.22101163602365	1.25870113723364	0.831520912363651	0.855555139385704	0.829937107028983	0.149571201027133	NA	NA	0.56194716758927	0.2725694334588	68.7918247572142
a2064	gain_cnaOV19	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	5.09269581803487	3.92303411442465	1.16966170361023	2.02263612265666	1.42047707660729	0.796596485467115	0.578285777905478	0.8234287781707	0.149769741961174	NA	NA	0.315448777715051	0.423139140788181	68.8497654675189
a2065	loss_cnaOV57_(ZNRF3)	290	KIN001-260	IKK	4	27	2.99573227355399	NA	4.27096881085184	4.93606532643258	-0.665096515580738	0.955325659287544	0.870713900465341	0.755925281283691	0.696198735075062	0.763851955533599	0.149914694874832	NA	NA	0.655493186512903	0.262992437628434	68.883027357467
a2066	loss_cnaOV42	326	GSK690693	AKT	4	28	2.32630161961136	NA	5.25562839245219	3.99426011389931	1.26136827855288	0.672218230405351	1.46440306969878	0.897500208213845	1.87642676366017	0.861353205721112	0.15008062662675	NA	NA	0.0844513738169071	0.0198835031877298	68.9057317404819
a2067	PIK3R1_mut	1026	17-AAG	HSP90	5	28	0	NA	-2.29494058749177	-0.215812795932598	-2.07912779155918	1.58729317363643	2.25916217975347	0.951931910666544	1.30985745172454	0.920309223566261	0.150173249657191	NA	NA	0.0544584859824594	0.03916774945155	68.9057317404819
a2068	loss_cnaOV82	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.946645515726	1.55294920532877	1.39369631039722	0.844109241785962	1.46953641993356	0.970311595296712	1.65108524039904	0.948391813562696	0.1501819734595	NA	NA	0.312181661740487	0.0775888134552886	68.9057317404819
a2069	loss_cnaOV38	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	2.30258509299405	NA	2.68256858925543	1.98735721959403	0.695211369661403	1.26911797948601	1.27670674567315	0.545315523631434	0.547790970499815	0.544534891835988	0.150310270935747	NA	NA	0.677226052262302	0.206832419421169	68.9309173677474
a2070	SMAD4_mut	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.41667667403174	2.07374463467253	0.342932039359217	0.546631916254978	0.552201771982855	0.62163071414462	0.627354585712218	0.621026691254198	0.150447609026323	NA	NA	0.0370020592787813	0.306865519490063	68.9309173677474
a2071	loss_cnaOV40	288	KIN001-055	JAK3, MNK1	7	25	2.32630161961136	NA	4.31852063275745	3.65607854377924	0.662442088978203	1.07540835572847	0.980844203388899	0.662129337395213	0.615991205061328	0.6753795217318	0.150454811403761	NA	NA	0.709006514004641	0.176232190651814	68.9309173677474
a2072	loss_cnaOV59	326	GSK690693	AKT	4	28	2.32630161961136	NA	5.25437372228593	3.99443935249449	1.25993436979144	0.665127569312385	1.46492273939881	0.896384238740506	1.89427476460489	0.860068818583912	0.150645937872008	NA	NA	0.0844810468499008	0.0191218538300955	68.9511864663849
a2073	loss_cnaOV43_(NF1)	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	2.07402241209596	0.44098733700028	1.63303507509568	0.722138305529566	2.39785862184644	0.726502132362221	2.26138824459412	0.681038932077729	0.150712148050276	NA	NA	0.944199228353968	0.00818736350031232	68.9511864663849
a2074	loss_cnaOV35	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	-0.0069727982229188	-1.25431551885123	1.24734272062831	2.41077802536217	1.84952360672122	0.645024143267936	0.517402559466635	0.674412976452657	0.150717061809401	NA	NA	0.430032281552856	0.322856184526285	68.9511864663849
a2075	SMAD4_mut	1028	VX-702	p38	4	27	0.693147180559945	NA	3.92361363404288	3.23857745683322	0.68503617720966	0.715241028184289	0.922056456972897	0.758739063532615	0.957769689119615	0.742943853415037	0.150888829171749	NA	NA	0.50512668529227	0.15154449702688	68.9965005462392
a2076	loss_cnaOV56	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.99194961364096	3.99009867171732	1.00185094192364	1.51119067074869	1.05185153485576	0.920377866935138	0.662954689514655	0.952464210703484	0.151183500025972	NA	NA	0.814281762908859	0.369617520688892	69.0435216176471
a2077	loss_cnaOV56	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	5.18986475091224	4.43900051622579	0.750864234686452	1.30220616602146	0.863840086909235	0.833417465783639	0.576609337506452	0.869216705806045	0.151196085899565	NA	NA	0.515671925191207	0.42416061540934	69.0435216176471
a2078	loss_cnaOV57_(ZNRF3)	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.69487288798084	3.79168000755131	0.903192880429524	0.911032333962729	1.05273656118362	0.868565321756165	0.991394977718183	0.857947670606255	0.151209961008141	NA	NA	0.30273205489485	0.139250046951359	69.0435216176471
a2079	TP53_mut	333	T0901317	LXR	22	10	2.32630161961136	NA	4.90460036990187	4.42060479072536	0.483995579176515	0.779808964664918	1.62774887884956	0.438091824086771	0.620659162830331	0.29734044696046	0.151304072449799	NA	NA	0.00405931291655458	0.390203455242942	69.0520090699766
a2080	TP53_mut	203	BMS-345541	IKBKB	22	10	2.77258872223978	NA	3.43744859347814	2.92142397804284	0.516024615435302	1.14006849615785	0.661719005922304	0.505714294426215	0.45262597569739	0.779824382882984	0.151422486001244	NA	NA	0.0829790836388394	0.118893548232645	69.0520090699766
a2081	PIK3CA_mut	276	CAY10603	HDAC6	6	25	2.99573227355399	NA	0.816613176472413	1.58116875260848	-0.764555576136065	0.761165965349087	1.92358934293612	0.429951700199551	1.0044531822773	0.397462992266876	0.151455549101966	NA	NA	0.60365722376931	0.136676884575622	69.0520090699766
a2082	gain_cnaOV48_(SOX17)	306	TG101348	JAK2	3	29	2.32630161961136	NA	1.76468679426348	2.93364880693144	-1.16896201266796	0.790158254614726	1.39572593468369	0.857169659832683	1.47940239292689	0.83752976398828	0.151519653140815	NA	NA	0.617144523450174	0.100020405486483	69.0520090699766
a2083	loss_cnaOV44	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.99088632259774	3.99020866734248	1.00067765525526	1.5111694075494	1.05196215610993	0.919217405263218	0.662187607991625	0.951248720729347	0.151690431600511	NA	NA	0.814298053657154	0.370067944034173	69.0966502573535
a2084	loss_cnaOV56	1030	KU-55933	ATM	3	30	2.30258509299405	NA	5.01196089066794	4.06489813017698	0.947062760490967	1.13969560600657	0.989101646520596	0.947534320536846	0.830978688958379	0.957497911182828	0.151882571041496	NA	NA	0.51786819385176	0.283771182947197	69.1032389213353
a2085	ARID1A_mut	1066	AZD6482	PI3Kbeta	9	24	1.6094379124341	NA	1.59225337793871	2.6741862464173	-1.08193286847858	0.643672080776357	1.36486981470843	0.886637013609245	1.68087586954777	0.792700414954752	0.152030242417754	NA	NA	0.100500991524849	0.00453405711971239	69.1032389213353
a2086	NF1_mut	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	1.70752903558083	2.17155810204507	-0.46402906646424	0.792842574783782	0.507271023035614	0.856886657442489	0.585272639515842	0.914755713203161	0.152072078305597	NA	NA	0.0370508245797409	0.329663029129845	69.1032389213353
a2087	loss_cnaOV43_(NF1)	1025	SB 216763	GSK3A, GSK3B	4	19	2.30258509299405	NA	5.54447265652863	4.83689995485111	0.70757270167752	0.965486702061853	0.752392079776085	0.899787508478469	0.732866335876462	0.940430821504787	0.152094733950152	NA	NA	0.434642474878746	0.24306004044917	69.1032389213353
a2088	gain_cnaOV96	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.93785377238679	4.09119924130506	0.846654531081724	1.02137439028833	0.928598351261143	0.902338899034327	0.82893651841292	0.911755367572934	0.152109291039336	NA	NA	0.0421992978710412	0.196763483977409	69.1032389213353
a2089	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1175	AG-014699	PARP1, PARP2	8	25	1.6094379124341	NA	4.38782992820649	3.74542289381038	0.642407034396104	0.901178644299021	1.08402370170571	0.61442908759518	0.71285203933766	0.592613457976312	0.152141875955313	NA	NA	0.302807361954775	0.11757503416099	69.1032389213353
a2090	loss_cnaOV20	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	3.40787251399753	2.26035195232641	1.14752056167113	1.65428063224036	1.36366128134363	0.816225975379346	0.693667410055489	0.841499701847122	0.152330109187614	NA	NA	0.226628879060104	0.202988666517994	69.1285492651232
a2091	loss_cnaOV87, loss_cnaOV88	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	1.55231892882362	2.87281529856407	-1.32049636974045	1.05823879184934	1.68067206880103	0.801995577424403	1.24782457410468	0.785695433543127	0.152373507264172	NA	NA	0.3072442401516	0.145145554057557	69.1285492651232
a2092	KRAS_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	7	26	2.30258509299405	NA	3.51995247802278	2.42226768527048	1.0976847927523	0.807260240916122	1.79804634222155	0.663940132307302	1.35976570765654	0.610487486877604	0.152416170775657	NA	NA	0.630412297518117	0.0275200642924036	69.1285492651232
a2093	loss_cnaOV85	1024	CEP-701	FLT3, JAK2, NTRK1, RET	7	24	0.693147180559945	NA	0.770922965956012	-0.428648328288695	1.19957129424471	1.33559310035235	1.58534499055553	0.780460026419292	0.898156252775074	0.756662620054931	0.152748875179687	NA	NA	0.0909173347527825	0.0697459367408779	69.2240231726251
a2094	TP53_mut	304	SB52334	ALK5	22	10	2.99573227355399	NA	4.19179615350995	4.75129798665623	-0.559501833146284	1.11555468738285	0.825842465580593	0.539448777900041	0.501545858284099	0.677492205190655	0.152772588383304	NA	NA	0.337800831091539	0.126700092719208	69.2240231726251
a2095	loss_cnaOV44	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.64723387634847	4.660821220237	0.98641265611147	0.506472311199944	1.23720805212327	0.821209687158738	1.94761418205556	0.797289230714762	0.152889289269775	NA	NA	0.410808069874308	0.0443852299623771	69.2438347213215
a2096	loss_cnaOV102	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	1.58818638034903	0.456154701577	1.13203167877203	1.03077939182133	1.18253766420167	0.965318931607456	1.09822886230951	0.957290167612767	0.153119527799103	NA	NA	0.416935868273879	0.186925822907677	69.2543242039593
a2097	loss_cnaOV58	1248	FK866	NAMPT	5	27	0	NA	0.216980541094022	-2.06490187707643	2.28188241817045	3.21181461915516	2.54728395851363	0.862536087530616	0.710465169615137	0.895809990301179	0.153128562033451	NA	NA	0.0389735723559951	0.193314263423208	69.2543242039593
a2098	PIK3R1_mut	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	1.84405986645624	2.6607918702906	-0.816732003834362	0.753897391548167	1.03036010274708	0.817552902510501	1.08334637178829	0.792666565462736	0.153131417589799	NA	NA	0.381802994318639	0.0741312023935227	69.2543242039593
a2099	loss_cnaOV20	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.1433043895286	2.99186521651412	-0.848560826985525	0.59900795733347	1.14027143677938	0.782924522937164	1.41661027469979	0.744174412876838	0.153403902214302	NA	NA	0.376976585065095	0.0332848387657638	69.2776815402534
a2100	loss_cnaOV102	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	0.307283584771238	-1.48546967295762	1.79275325772885	2.24771651958191	1.77295528848569	0.991299673617429	0.797588682607679	1.01116664891198	0.153528316066111	NA	NA	0.0663441590210793	0.299080070523773	69.2776815402534
a2101	loss_cnaOV84	286	KIN001-236	TIE2	6	26	2.32630161961136	NA	5.15687375974228	4.71157768436471	0.445296075377571	0.62451806984058	0.64926406658806	0.690161466426958	0.713023524669576	0.68584740522857	0.153546650816127	NA	NA	0.755236306902149	0.158207415639167	69.2776815402534
a2102	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.64561907017922	4.66099423518371	0.984624834995506	0.50870596557025	1.23728309060702	0.819627770588545	1.93554804078572	0.795795919681112	0.153607357759776	NA	NA	0.4108679446916	0.0453158624015041	69.2776815402534
a2103	loss_cnaOV1	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.93716352354809	1.55393010107131	1.38323342247678	0.743188616364692	1.47438145347075	0.962413215774902	1.86121449120529	0.938178799808282	0.153656498311344	NA	NA	0.312472028638347	0.0543837362581409	69.2776815402534
a2104	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.4046079318697	4.44357785680273	0.961030075066976	1.03213275725674	0.980372511835933	0.976747989446981	0.931110914085561	0.980270319153753	0.153679029347695	NA	NA	0.17884292120177	0.242820509756724	69.2776815402534
a2105	loss_cnaOV35	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-3.27258140862882	-4.91313128300142	1.6405498743726	3.7554982537445	1.6142322799943	0.824568278930686	0.436839472029271	1.01630347423011	0.153694161041632	NA	NA	0.324417046723859	0.530019550267977	69.2776815402534
a2106	ARID1A_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	9	22	0.693147180559945	NA	-1.12286599256089	0.237031582536882	-1.35989757509777	1.14532745110453	1.60358951515637	0.911884567570124	1.18734391093684	0.848033466323311	0.15378242059284	NA	NA	0.0909745668697154	0.0149106580779131	69.2842817329993
a2107	loss_cnaOV44	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.93592906220837	2.52702799921889	1.40890106298948	1.94071669614062	1.64456416557022	0.846054249147758	0.725969465708864	0.856701789133882	0.15386005591995	NA	NA	0.63049506544493	0.334584781092276	69.2842817329993
a2108	TP53_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	23	10	0.693147180559945	NA	2.03511339763963	1.05394108651805	0.981172311121582	1.44021597824729	2.07656876644421	0.594492734444612	0.681267480670255	0.472496903053051	0.153928338022034	NA	NA	0.216490447778067	0.197442464289492	69.2842817329993
a2109	loss_cnaOV20	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	0.478277702492974	-0.47736028762808	0.955637990121054	0.915181672769772	1.42945510617738	0.695537232094262	1.04420577744836	0.668533055701624	0.154000886961492	NA	NA	0.885807286148438	0.0870806042060015	69.2842817329993
a2110	loss_cnaOV56	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.20617503141596	2.66533181484377	0.540843216572191	0.908168419788478	0.515613569621523	0.982348053194075	0.595531847163502	1.04893130909876	0.15408592956788	NA	NA	0.124792173693623	0.411185359649509	69.2896877201881
a2111	loss_cnaOV16, loss_cnaOV17	196	Phenformin	AAPK1 (AMPK) agonist	6	25	8.29404964010203	NA	9.6360218048112	8.54666543478082	1.08935637003038	1.23978103771326	1.74061448031084	0.654249818277601	0.878668359083527	0.625845862109481	0.154549461223631	NA	NA	0.91939893237008	0.105507521892717	69.4553334432231
a2112	loss_cnaOV52, loss_cnaOV53	1052	RO-3306	CDK1	9	24	1.6094379124341	NA	3.85851784237912	3.34051609198503	0.518001750394086	0.817771379856735	0.901803258633126	0.588046719443205	0.633431009146878	0.574406607466941	0.154679962519143	NA	NA	0.78847496071926	0.135082727476304	69.4553334432231
a2113	PIK3CA_mut	255	CP724714	ERBB2	6	26	2.32630161961136	NA	4.04446583500449	4.50059348625103	-0.456127651246535	0.940036510237209	0.940533859818239	0.485009487789001	0.48522333577388	0.484966752111065	0.154718133216551	NA	NA	0.780301270182772	0.317332670314714	69.4553334432231
a2114	loss_cnaOV43_(NF1)	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	1.15475343880712	-0.0755490235731694	1.23030246238029	2.67003491005186	0.924902887406634	0.974614860092008	0.460781414410944	1.33019636886417	0.154783444133695	NA	NA	0.862780210784043	0.509531066432672	69.4553334432231
a2115	loss_cnaOV87, loss_cnaOV88	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	1.2704093580551	0.182195545952489	1.08821381210261	1.12634565103356	1.10004192243417	0.987706849212813	0.96614552655665	0.989247582214512	0.154915635326885	NA	NA	0.136006940066472	0.230172305566781	69.4553334432231
a2116	loss_cnaOV20	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-3.30721768944476	-4.3457089436292	1.03849125418444	2.57046404381406	0.955348735172095	0.803134989761524	0.404009251435987	1.08702844935192	0.154918909287094	NA	NA	0.204782659963871	0.4204556971656	69.4553334432231
a2117	loss_cnaOV40	1061	SB590885	BRAF	8	25	1.6094379124341	NA	4.42411617956646	3.76863539055694	0.655480789009523	1.16952117811354	1.28654985116305	0.519779933326898	0.560469362399088	0.509487283696752	0.155039288342838	NA	NA	0.562307237868261	0.201493606890286	69.4553334432231
a2118	SMAD4_mut	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	1.15416152925613	-0.0754380405323577	1.22959956978848	1.62757458878498	1.20543831981547	0.973979524377624	0.755479704746687	1.02004353899809	0.155039900071796	NA	NA	0.862791206444231	0.319439152571825	69.4553334432231
a2119	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.91856754646594	3.91989485561114	0.998672690854801	0.399328026342743	1.04542368479357	0.983696385155935	2.50088304595391	0.95528033789669	0.15521209917136	NA	NA	0.0952765656903248	0.0176874895981607	69.4956573869905
a2120	gain_cnaOV49	1248	FK866	NAMPT	3	29	0	NA	-3.31116176234086	-1.54255043753692	-1.76861132480393	3.15699468001777	2.69588040516992	0.648069355633102	0.560219925614185	0.656042204770006	0.155325711263472	NA	NA	0.0390425999852008	0.436531828949089	69.4956573869905
a2121	gain_cnaOV49	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	3.9252365985052	4.37265309172379	-0.447416493218594	0.0850825014156253	0.596887469334239	0.776265106398682	5.25861940792007	0.749582653691218	0.155391515586366	NA	NA	0.2401329624548	0.0012116695986917	69.4956573869905
a2122	TP53_mut	170	Shikonin	unknown	11	7	2.77258872223978	NA	-0.232854281343474	0.336905496792337	-0.569759778135811	0.772729710626754	0.70187051953742	0.76278610178729	0.737333857234095	0.811773343196293	0.155422886507186	NA	NA	0.562517882854454	0.129091630629332	69.4956573869905
a2123	loss_cnaOV57_(ZNRF3)	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	4.13834583287093	2.84862431504184	1.2897215178291	1.26648653758081	1.60636115075897	0.818519410434189	1.01834601439402	0.802883907656588	0.155762402589983	NA	NA	0.654220168159213	0.132004200953823	69.506902592437
a2124	loss_cnaOV83	1024	CEP-701	FLT3, JAK2, NTRK1, RET	5	26	0.693147180559945	NA	0.940140776508243	-0.368915499991454	1.3090562764997	1.48465666563271	1.55311912743926	0.847913160676314	0.881723233931547	0.842856322720094	0.15579004995609	NA	NA	0.0910845578845282	0.124835624532907	69.506902592437
a2125	SMAD4_mut	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.20442131388014	2.6655132338992	0.538908079980946	0.91040291008007	0.515528836153667	0.978527617359209	0.591944592898488	1.04535002154624	0.155822494029094	NA	NA	0.124900243745113	0.413538030093819	69.506902592437
a2126	loss_cnaOV55	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.64583723731933	4.23704732093943	0.408789916379893	0.563066384459314	0.56600946505553	0.723007797408889	0.726006608923093	0.722231590844135	0.155832077578785	NA	NA	0.240168781826763	0.122790512352586	69.506902592437
a2127	loss_cnaOV34	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.55780844965783	3.35412368785951	-0.796315238201688	1.18058454308142	1.20835442753932	0.661013253334477	0.674509286834507	0.659008002994034	0.155987248100166	NA	NA	0.590327154236326	0.219446698621307	69.506902592437
a2128	gain_cnaOV18_(CCNE1)	185	OSI-906	IGF1R	4	14	0.940007258491471	NA	1.34050082651437	2.45598185480805	-1.11548102829368	1.85864195602355	1.03273301771267	0.906478874575787	0.600159177876403	1.08012526874011	0.156009096361623	NA	NA	0.668648733595332	0.321511396010175	69.506902592437
a2129	loss_cnaOV54	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	10	22	0.246860077931526	2.32630161961136	0.410531890932246	1.27401677430663	-0.86348488337438	1.21797531484488	1.61426182126835	0.573225154043827	0.708951054138852	0.534910057338732	0.15615254332126	NA	NA	0.785027753811673	0.108209516839223	69.506902592437
a2130	gain_cnaOV49	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	2.36025942080172	3.0491349668903	-0.688875546088588	0.510657708309336	1.01845328074956	0.693344031558332	1.34899666621951	0.676393860287424	0.156253012336703	NA	NA	0.0795050234597852	0.121766062577295	69.506902592437
a2131	loss_cnaOV33_(ZFHX3)	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	1.99225977871302	3.03576052420285	-1.04350074548984	0.602703451428939	1.25574969862182	0.86492895202047	1.73136679907145	0.830978296578585	0.15629494550123	NA	NA	0.218535531048661	0.0276745935580204	69.506902592437
a2132	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	1.29487046874466	-0.00801129787205748	1.30288176661672	2.43445105237209	1.50624197401759	0.820571329605994	0.53518503292445	0.864988354521518	0.156306128945191	NA	NA	0.44850628337999	0.453070223411173	69.506902592437
a2133	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.36334646247589	5.87291457793816	0.490431884537736	0.701510596237107	0.682118338490155	0.716323464436548	0.699108305944922	0.71898357933506	0.156313702752154	NA	NA	0.906125196045163	0.203222293196191	69.506902592437
a2134	loss_cnaOV56	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.29582047016679	2.40589522633441	-1.11007475616762	1.24854607390929	1.21900410987454	0.909104160431855	0.889093946442759	0.910640700203932	0.156442817096316	NA	NA	0.839859395249834	0.258763977832604	69.506902592437
a2135	loss_cnaOV43_(NF1)	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.85614153246955	4.07497356236079	0.781167970108762	1.10847720532947	0.907896893411522	0.83357950559099	0.704721726665168	0.860414850824566	0.156472624011184	NA	NA	0.042343953398664	0.196878692835162	69.506902592437
a2136	gain_cnaOV4_(KRAS)	154	CHIR-99021	GSK3B	6	13	0.940007258491471	NA	2.80812436174781	3.55559540905842	-0.747471047310613	0.995530850373599	0.887638884502414	0.811863844944641	0.750826603746237	0.842089120205256	0.156473611845047	NA	NA	0.168095793909791	0.150742235468414	69.506902592437
a2137	PTEN_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	5.24232755602616	3.85988451958267	1.38244303644349	1.20120371741302	1.45781559733	0.963897530856295	1.15088141703457	0.948297602917299	0.156812752601987	NA	NA	0.316031689300611	0.0986340100680635	69.5936031659577
a2138	loss_cnaOV84	1066	AZD6482	PI3Kbeta	6	27	1.6094379124341	NA	3.18550725284762	2.19991506660659	0.985592186241035	1.3497884112758	1.23948168002751	0.783504761503254	0.730182729387541	0.795164787122275	0.156838998389308	NA	NA	0.100761815260957	0.144708296007783	69.5936031659577
a2139	TP53_mut	1013	Nilotinib	ABL	15	6	0.693147180559945	NA	3.44346214428098	2.76396471587717	0.679497428403806	0.851800633234209	1.30547808459295	0.685306291870137	0.797718858019413	0.520497001384495	0.157049033860931	NA	NA	0.5471712248881	0.278293727384019	69.5936031659577
a2140	loss_cnaOV84	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	1.38629436111989	0.693147180559945	3.62655889349823	2.64044529710678	0.986113596391446	1.39461031907257	1.54667772808189	0.647405384781751	0.707088986009527	0.637568886192196	0.157215708339847	NA	NA	0.967933662988459	0.163393586347591	69.5936031659577
a2141	PIK3CA_mut	345	KIN001-270	CDK9	6	26	2.99573227355399	NA	5.37508841777966	5.14827110665315	0.22681731112651	0.82053054151414	0.762306454745436	0.293684840431345	0.276427627797937	0.29754085081472	0.157251433926768	NA	NA	0.319936638720062	0.555583443905727	69.5936031659577
a2142	loss_cnaOV34	152	CP466722	ATM	5	27	2.77258872223978	NA	2.20838403499901	2.72812643501586	-0.51974240001685	0.759234277031209	0.802793752511245	0.652022538339514	0.684561295163292	0.647417096098503	0.157304404419216	NA	NA	0.544531531201851	0.214675104287576	69.5936031659577
a2143	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	3.0095648199031	1.82863172895595	1.18093309094715	0.675878143449386	1.33914782234542	0.904613172327695	1.74725740489282	0.881854169675478	0.15732763109257	NA	NA	0.834428489510025	0.0645947690897284	69.5936031659577
a2144	loss_cnaOV34	255	CP724714	ERBB2	5	27	2.32630161961136	NA	4.9501975627395	4.31597177180949	0.634225790930015	0.778340957200959	0.949240158542376	0.68323177819783	0.81484314176501	0.668140496609322	0.157484540476248	NA	NA	0.780402060945082	0.154470796876878	69.5936031659577
a2145	loss_cnaOV83	341	EX-527	SIRT1	5	26	2.99573227355399	NA	6.14894907522297	5.70107558728728	0.447873487935683	0.439183870220307	0.558164056660481	0.824351061910231	1.01978583072966	0.802404745685935	0.157491269401603	NA	NA	0.100767486763115	0.0880681498615791	69.5936031659577
a2146	BRCA1_mut	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.26251450554083	-3.47113967937136	1.20862517383053	1.42835237007812	1.82702064385399	0.675246705500033	0.846167373786363	0.661527924107641	0.157571091615382	NA	NA	0.12835536648545	0.194374767423256	69.5936031659577
a2147	PIK3CA_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	-1.38629436111989	0.693147180559945	-1.49216562791829	-2.29357090923443	0.801405281316136	0.471058736053761	1.38308399529988	0.636431690575736	1.7012852537877	0.579433558655543	0.157577630613752	NA	NA	0.597535654647066	0.0196694264304833	69.5936031659577
a2148	gain_cnaOV19	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	-0.0409099483648272	0.840937604029265	-0.881847552394093	0.978329131083967	1.0257778707406	0.862288172179794	0.901381267689561	0.859686660775207	0.157597095324399	NA	NA	0.76549406065948	0.25361855128578	69.5936031659577
a2149	gain_cnaOV95_(MECOM)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	8	23	2.30258509299405	NA	2.06306268369341	1.18153358734352	0.881529096349885	1.11368138635492	1.51017660742216	0.618786039993218	0.791545146709447	0.583725831811576	0.157639523213124	NA	NA	0.463371044905863	0.0987962327258173	69.5936031659577
a2150	loss_cnaOV55	134	Etoposide	TOP2	4	15	2.77258872223978	NA	1.02362936124926	2.61922584197914	-1.59559648072988	0.987273912428597	1.84072994621414	0.927051904492048	1.61616392436104	0.866828121100312	0.157695647144686	NA	NA	0.38472360557067	0.0436838395849859	69.5936031659577
a2151	KRAS_mut	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.14802105726168	4.71175371098052	-0.563732653718844	0.436040181744695	1.00674557222135	0.611865972535946	1.2928456534974	0.559955433898741	0.157863043789568	NA	NA	0.941492301928972	0.0404455970920123	69.6350895603355
a2152	loss_cnaOV87, loss_cnaOV88	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.44312238877171	1.43114168999392	1.01198069877779	2.37052035194511	0.753717707921643	0.987985276818992	0.426902345701196	1.34265214700647	0.157942859363685	NA	NA	0.435331250093538	0.537423010889379	69.6379223967166
a2153	MLL2_mut	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-2.58695337512957	-1.96961558190126	-0.617337793228302	2.17953588484434	1.50679840221043	0.395090912712549	0.28324277545556	0.409701651078661	0.158068945783169	NA	NA	0.0328252147254342	0.675507158723096	69.6560135783286
a2154	gain_cnaOV49	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	-1.14314356093331	-0.0522024440870236	-1.09094111684629	1.08748002062736	1.61838197202871	0.687216312086396	1.0031826756844	0.67409371563794	0.158182583900483	NA	NA	0.0912136467418414	0.214758343647658	69.6560135783286
a2155	NF1_mut	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	2.83968820132428	1.34410469146159	1.49558350986269	1.63505151835735	1.88992701527266	0.801488814838805	0.914701153493456	0.791344585148927	0.158256855059586	NA	NA	0.776471911878599	0.164953343503299	69.6560135783286
a2156	loss_cnaOV36	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	10.080127363916	8.61579945023713	1.46432791367885	1.22665173176115	1.692264619286	0.879824681950074	1.19376011606526	0.865306700258658	0.158292896157394	NA	NA	0.919451906203565	0.159504393579498	69.6560135783286
a2157	KRAS_mut	257	NPK76-II-72-1	PLK3	7	25	2.32630161961136	NA	3.74015874710818	3.08677082362955	0.653387923478636	0.928442753814572	1.26995249634034	0.540262292274463	0.703746053048662	0.514497924419633	0.158350954160358	NA	NA	0.590474962223123	0.155318837325868	69.6560135783286
a2158	loss_cnaOV57_(ZNRF3)	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	3.51146340025689	1.83196573988675	1.67949766037014	3.47651497458469	1.65961248527292	0.87460813724401	0.483098065921828	1.01198181820978	0.158549491309463	NA	NA	0.122025690528244	0.407867978562385	69.7110283355064
a2159	loss_cnaOV83	173	FH535	unknown 	3	15	3.46573590279973	NA	3.31147257674217	2.33389715008607	0.977575426656103	1.8434349967561	1.33484899776457	0.694053659395678	0.530301002409276	0.732349073410713	0.158749397270733	NA	NA	0.102722451546666	0.45971610365592	69.7553747914593
a2160	gain_cnaOV4_(KRAS)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	6	13	2.07944154167984	NA	2.91191602519053	3.71929445083085	-0.807378425640318	0.911382706947908	1.10854876163935	0.765728207513967	0.885882977025222	0.728320172805342	0.15898961056377	NA	NA	0.761218581179951	0.120534186586962	69.7553747914593
a2161	loss_cnaOV84	298	OSI-930	KIT, VEGFR, PDGFR	6	26	2.32630161961136	NA	5.06207005084629	4.31068060103966	0.751389449806635	1.0681601376813	0.918363052703001	0.795138209304876	0.703442698617929	0.818183448904095	0.159000572144457	NA	NA	0.0270750232533434	0.156460442627329	69.7553747914593
a2162	loss_cnaOV20	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	-0.896016514596234	0.313091447646059	-1.20910796224229	1.35531692594073	1.60288708168429	0.769612555219568	0.892121937754928	0.754331341276879	0.159014655902193	NA	NA	0.448718729998724	0.124117735980585	69.7553747914593
a2163	loss_cnaOV102	333	T0901317	LXR	3	29	2.32630161961136	NA	5.71763463785603	4.65359834936299	1.06403628849303	0.94554381283462	1.09153428365582	0.983021232035983	1.12531674793915	0.974807941835147	0.159355141879129	NA	NA	0.00410379474670421	0.179660756882683	69.7553747914593
a2164	loss_cnaOV40	163	JQ1	BRD4	4	15	0.940007258491471	NA	1.17220958696919	-0.200475153472816	1.372684740442	2.09086952785913	1.72441122271608	0.764928710356166	0.656513819801811	0.796030971243575	0.159356076837799	NA	NA	0.562058053856547	0.291226539513775	69.7553747914593
a2165	TP53_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	17	6	2.30258509299405	NA	1.75791943942385	1.01126174933135	0.746657690092499	1.1197363277698	0.658892497844856	0.725680350621708	0.666815634694669	1.13320107989499	0.15935916312602	NA	NA	0.435487790576525	0.0692034394735117	69.7553747914593
a2166	loss_cnaOV39	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	23	1.6094379124341	NA	1.6818952799686	0.944386318041303	0.737508961927294	1.66938117795907	1.37070495550091	0.503862945293749	0.441785837569433	0.538050846732204	0.159417569454397	NA	NA	0.807986003305394	0.238758230720049	69.7553747914593
a2167	loss_cnaOV43_(NF1)	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.40792513218154	4.85368767703867	0.554237455142869	0.764404114446806	0.804754506404881	0.693089284290331	0.725058178871744	0.688703760875898	0.159500366297094	NA	NA	0.944478905934828	0.1915096545235	69.7553747914593
a2168	loss_cnaOV41	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.78415229136715	3.56261984077771	1.22153245058944	1.02270182241127	1.56588832156607	0.810656786631073	1.19441700779351	0.780089124981636	0.159544358073765	NA	NA	0.154116811689685	0.0558555558791268	69.7553747914593
a2169	loss_cnaOV43_(NF1)	293	MP470	PDGFR	5	27	2.99573227355399	NA	5.0090525475212	3.87150016828678	1.13755237923443	1.0752728771137	1.80935236354841	0.657707724973883	1.05791971828388	0.628706935228204	0.159667894956671	NA	NA	0.612280975071158	0.0879169479556261	69.7553747914593
a2170	loss_cnaOV83	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.85206260775304	4.07572891878977	0.77633368896327	1.05638081752307	0.918068327191702	0.827921924477672	0.73489945679207	0.845616460092914	0.159793384975492	NA	NA	0.0424512220326458	0.182359344700133	69.7553747914593
a2171	loss_cnaOV87, loss_cnaOV88	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.31749320273066	4.51301760576389	0.804475596966764	1.13136557902601	0.904040632358862	0.873534608468733	0.711066000133514	0.889866636710445	0.159996091045687	NA	NA	0.941513103627507	0.342563684422543	69.7553747914593
a2172	NF1_mut	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.93437091962713	2.45031211720561	0.484058802421521	0.279479987570828	0.639074564699433	0.790058648789393	1.73199808196945	0.757437127307956	0.160152666912437	NA	NA	0.854085454848803	0.0287628141227647	69.7553747914593
a2173	loss_cnaOV59	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	6.24358289056494	5.43805478565824	0.805528104906701	0.76265585690512	0.968021118051634	0.848383751338292	1.05621440865288	0.832138979083444	0.160210962522582	NA	NA	0.29079609841053	0.121407077087193	69.7553747914593
a2174	loss_cnaOV59	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.92629602701198	4.09285034778718	0.8334456792248	1.27742514083491	0.894298957613488	0.88695805155665	0.652441894700825	0.931954210758469	0.160274411633339	NA	NA	0.0424665646717567	0.286045184534593	69.7553747914593
a2175	NF1_mut	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	9.89637231936948	8.58878805262629	1.30758426674319	1.14284372969042	1.71269224410691	0.786363932535615	1.14414966173668	0.763467150179704	0.160312337863794	NA	NA	0.919479881482696	0.101446365381619	69.7553747914593
a2176	loss_cnaOV83	1017	Olaparib	PARP1, PARP2	5	26	1.6094379124341	NA	4.76422766878761	3.81683061820026	0.947397050587349	0.670207034958026	1.17699771027173	0.845283969969621	1.41358863928768	0.804926842524293	0.16033612959797	NA	NA	0.0745831751086784	0.0320878471015245	69.7553747914593
a2177	gain_cnaOV51_(MYC)	283	GSK2126458	PI3K, MTOR	8	24	-2.05572501506252	0.0237165266173161	-3.43715732265774	-2.49719151380479	-0.939965808852945	1.87652900561029	1.68694813977508	0.542379871012404	0.500906623901209	0.557198995446459	0.160364787737804	NA	NA	0.688048267794131	0.234535207384113	69.7553747914593
a2178	loss_cnaOV40	253	XMD14-99	EPHB3, CAMK1	7	25	2.32630161961136	NA	5.21200554909273	4.76152021761934	0.450485331473391	0.587921827358306	0.597011034632961	0.756858331834531	0.766233384287747	0.75456784772889	0.160545056419892	NA	NA	0.0438739980294622	0.10517658091513	69.7553747914593
a2179	gain_cnaOV48_(SOX17)	1061	SB590885	BRAF	3	30	1.6094379124341	NA	2.87977933937958	4.03231587274388	-1.15253653336429	1.42846307850655	1.2345559136804	0.923524909935141	0.806836767926312	0.933563656852451	0.16056380946244	NA	NA	0.562656470836709	0.294630426096726	69.7553747914593
a2180	loss_cnaOV35	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.76922033216373	2.20259418299631	0.566626149167418	0.759450239488513	0.900453348008333	0.642181851752758	0.746100428579809	0.629267635486846	0.160611538259815	NA	NA	0.583575831324105	0.186423737901627	69.7553747914593
a2181	TP53_mut	205	BMS-708163	g-secretase	22	10	2.32630161961136	0.940007258491471	5.15629585535513	4.85456378762349	0.301732067731645	0.598193425228318	0.622790110051111	0.498172965820424	0.504405523374784	0.484484359757868	0.160696684616995	NA	NA	0.101182398853637	0.215830413942969	69.7553747914593
a2182	gain_cnaOV72_(ASXL1)	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.35533349936183	3.57703513003146	0.778298369330371	0.776664179269014	1.25076785910247	0.648493543339218	1.00210411411389	0.622256451240172	0.160845559279663	NA	NA	0.186419576059734	0.0997515933417477	69.7553747914593
a2183	loss_cnaOV83	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	4.88654452474893	3.70447238483706	1.18207213991187	1.5783383813985	1.46827494963567	0.794248805017434	0.748934546509906	0.805075466420767	0.160852855217485	NA	NA	0.729984595022277	0.240978657667659	69.7553747914593
a2184	gain_cnaOV19	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	1.54395398225882	2.97865580354912	-1.4347018212903	0.430068190030001	1.87795896569309	0.789305695548754	3.33598683778546	0.763968674236073	0.160881542447941	NA	NA	0.33295384957263	0.00482303179026111	69.7553747914593
a2185	PTEN_mut	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	2.31977346759599	3.94465596993889	-1.6248825023429	1.59532670632174	1.46143380215831	1.1016731459413	1.01852648482849	1.11184133003028	0.160925875763704	NA	NA	0.154204738550396	0.13117886393961	69.7553747914593
a2186	PIK3R1_mut	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	4.48503814831815	5.01848892415714	-0.533450775838989	0.470773841737311	0.839591310630861	0.665486863995351	1.13313597431493	0.635369576941141	0.160968621538508	NA	NA	0.944491914813737	0.0724169978387458	69.7553747914593
a2187	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.95217035573772	2.70735740402031	1.24481295171741	1.16008413924767	1.37067197337249	0.916888374148126	1.07303678207745	0.908177139315539	0.161006640185562	NA	NA	0.617710520674473	0.194010922945458	69.7553747914593
a2188	loss_cnaOV84	255	CP724714	ERBB2	6	26	2.32630161961136	NA	4.88691987667375	4.30618101509658	0.580738861577169	0.84961486677934	0.944337637152416	0.624973690252186	0.683531896962435	0.614969518029956	0.161017456182675	NA	NA	0.78052782892917	0.177364082879936	69.7553747914593
a2189	loss_cnaOV20	192	LFM-A13	BTK	4	15	2.77258872223978	NA	5.16327573342321	4.60823447123199	0.555041262191225	0.526726856089052	0.682582623342375	0.843825762941127	1.05375538720848	0.813148830940607	0.161052161101347	NA	NA	0.954625434963474	0.130176644900023	69.7553747914593
a2190	loss_cnaOV1	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.01419256785776	2.56219466402387	-0.548002096166114	0.717165654049173	0.60464132248387	0.894279555117889	0.764122058930251	0.906325908912275	0.161174193223048	NA	NA	0.854109752556541	0.315024971828916	69.7553747914593
a2191	SMAD4_mut	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.43896864489231	2.8888902482408	0.550078396651514	0.568697203725148	0.572628316791901	0.961394437220296	0.967260596761028	0.960620319535157	0.161326692627098	NA	NA	0.841670534166257	0.227846946875428	69.7553747914593
a2192	loss_cnaOV34	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	2.66839255908984	3.41985760579653	-0.751465046706692	0.923169930958404	1.1021060453615	0.695825309152236	0.81400511596662	0.681844591878819	0.161470093730357	NA	NA	0.949532354614786	0.154048622949605	69.7553747914593
a2193	loss_cnaOV58	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.8028565505816	4.38694844730081	0.415908103280795	0.557134910346126	0.536076229839102	0.771727068524509	0.746512371702587	0.77583761437366	0.161498769496742	NA	NA	0.351575968123403	0.178723697075562	69.7553747914593
a2194	gain_cnaOV94	253	XMD14-99	EPHB3, CAMK1	7	25	2.32630161961136	NA	5.21130555969446	4.76171621465086	0.449589345043601	0.576552908520085	0.599929698070641	0.755196314233866	0.779788530071979	0.749403382578775	0.16166661123468	NA	NA	0.0439102949496925	0.100967121669894	69.7553747914593
a2195	loss_cnaOV34	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	4.33349932341565	3.75349699756674	0.58000232584892	1.13176043648412	0.793600173989007	0.686495870848987	0.512478000777915	0.73084954471917	0.161727459314936	NA	NA	0.921661046601358	0.324667710483687	69.7553747914593
a2196	gain_cnaOV96	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.9454644304225	3.183362814809	0.762101615613507	1.02186893804349	1.0874240765812	0.706360220468076	0.74579193792959	0.700832023151	0.161730104301103	NA	NA	0.94953450203085	0.181803605531762	69.7553747914593
a2197	PIK3R1_mut	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	1.71729138497767	0.60743685852063	1.10985452645704	1.74838407731547	0.812262688364204	1.12147670454763	0.6347887405616	1.36637388662053	0.161831853741958	NA	NA	0.327704784359402	0.38650857992011	69.7553747914593
a2198	loss_cnaOV16, loss_cnaOV17	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-3.30058702228582	-4.90788023044073	1.60729320815491	3.54957560913528	1.68062729519302	0.806219970519514	0.452812782468512	0.956365050568997	0.161844261871936	NA	NA	0.325600304604709	0.51706853504632	69.7553747914593
a2199	loss_cnaOV81_(RB1)	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	5.02335025131859	3.44957306093595	1.57377719038265	0.626416702981875	2.06815472462964	0.79806213720416	2.51234870157698	0.760957181607614	0.161900559921677	NA	NA	0.740509109853222	0.00651640558277524	69.7553747914593
a2200	loss_cnaOV82	1248	FK866	NAMPT	3	29	0	NA	0.700551205915347	-1.95755522735653	2.65810643327188	3.4399328271543	2.59848410736602	0.998212694622696	0.772720447413739	1.02294504158669	0.161985846026493	NA	NA	0.0392457285544244	0.310964394312785	69.7553747914593
a2201	loss_cnaOV102	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.99328909376788	0.7289292907512	1.26435980301668	0.673888931994926	1.33619191465058	0.969856736500593	1.87621393227779	0.946241171761109	0.162010884819831	NA	NA	0.152456479756669	0.053556987394296	69.7553747914593
a2202	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	4.31282752321949	2.87504764079299	1.4377798824265	0.866011454197114	1.61670204903123	0.911251950937255	1.66023194665418	0.889328917030845	0.162021064610068	NA	NA	0.654556912955975	0.0750014479391854	69.7553747914593
a2203	gain_cnaOV18_(CCNE1)	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	0.520439473466284	-0.146768680134464	0.667208153600747	0.0353431585138028	0.996346431203817	0.705828780261109	18.8780002030712	0.669654783421672	0.162026052494244	NA	NA	0.537746360829283	0.00149448023601193	69.7553747914593
a2204	loss_cnaOV81_(RB1)	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-0.660828000431629	-2.17598615776176	1.51515815733013	0.912608062173851	1.53898741497409	1.00729412429572	1.66025068167926	0.984516275174111	0.162042679485449	NA	NA	0.0329351836299742	0.0769174394252671	69.7553747914593
a2205	gain_cnaOV96	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.44411470243846	1.25567833958128	1.18843636285719	1.23793817913141	1.44049054660995	0.836410735955711	0.960012691175778	0.825021979945689	0.162142986267244	NA	NA	0.463713837443922	0.149513218845194	69.7553747914593
a2206	SMARCA4_mut	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	-0.714663212972245	0.380702803055223	-1.09536601602747	0.803832921319994	1.11872920656732	0.994761617463317	1.36267871963833	0.979116313042784	0.162244408210824	NA	NA	0.136454523991058	0.12452092450066	69.7553747914593
a2207	loss_cnaOV81_(RB1)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	2.12185774478948	1.03628990122338	1.0855678435661	1.55803379544193	1.44891457453023	0.743625688459905	0.696755004122476	0.749228327638338	0.16227621215778	NA	NA	0.808071567254672	0.262447866468059	69.7553747914593
a2208	gain_cnaOV72_(ASXL1)	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	4.79478216050725	3.43361244107202	1.36116971943523	1.17005946497077	2.07586355581016	0.687741352936245	1.16333379643165	0.655712518111048	0.162363750855606	NA	NA	0.740527989903631	0.0669329189766433	69.7553747914593
a2209	gain_cnaOV95_(MECOM)	226	GSK1070916	AURKB	9	23	0.940007258491471	2.32630161961136	1.73239463098954	2.54154280559584	-0.8091481746063	2.12440478846172	1.02851212025496	0.575147039804713	0.380882296538318	0.786717199215616	0.162405087467951	NA	NA	0.815973413398805	0.301070055299882	69.7553747914593
a2210	loss_cnaOV20	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.57144712274635	2.49147826962357	1.07996885312278	1.48521000905359	1.69539768313326	0.646779307203391	0.727148919371315	0.637000312001659	0.16251313085188	NA	NA	0.630972987966598	0.193168439075736	69.7553747914593
a2211	loss_cnaOV54	1054	PD-0332991	CDK4, CDK6	11	22	1.38629436111989	0.693147180559945	3.06766588386665	1.8924022481596	1.17526363570705	1.71903307020349	1.70909485510727	0.686362674953368	0.683677153207951	0.68765266725543	0.162662035956587	NA	NA	0.101553601336654	0.078401553142684	69.7553747914593
a2212	loss_cnaOV83	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	2.84933388150263	1.73095370754711	1.11838017395552	0.66509547362838	1.39969753278754	0.842188869499605	1.68153328101043	0.799015607127796	0.162670975088159	NA	NA	0.0299808675177846	0.0160515038778081	69.7553747914593
a2213	SMAD4_mut	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.40656848641628	3.59680611006982	0.809762376346456	1.07846979163921	1.21637323435311	0.672717442956324	0.750843818365708	0.665718673740057	0.162693804056087	NA	NA	0.186544591708967	0.236125184741146	69.7553747914593
a2214	loss_cnaOV102	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.50295171632988	2.26672983888246	1.23622187744741	1.63546258235913	1.23602624641226	0.976782308038295	0.755885148814706	1.00015827417558	0.162777573736389	NA	NA	0.101072114479123	0.319264952389088	69.7597685359816
a2215	loss_cnaOV21, loss_cnaOV22	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-1.27003637741119	-0.687428023651417	-0.582608353759769	0.240747118910533	0.943867930463715	0.636759186330421	2.42000135410252	0.617256222990369	0.162902279798996	NA	NA	0.0370090990286778	0.023234103515205	69.7730930057386
a2216	loss_cnaOV58	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.10052342820632	4.46630320802439	-0.365779779818066	0.864112500033924	0.576131922278603	0.587807865989489	0.423301109292721	0.634888930249527	0.16295573704376	NA	NA	0.258144799352688	0.40732511636634	69.7730930057386
a2217	gain_cnaOV72_(ASXL1)	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.66371220718602	2.47500236168792	1.1887098454981	0.762645003987752	1.75392011225179	0.716252635284816	1.55866732133892	0.677744577529221	0.163103690716449	NA	NA	0.631004525704667	0.0261947645797692	69.8049422088173
a2218	loss_cnaOV58	272	AR-42	HDAC	5	25	1.63315443905142	NA	1.24262660897258	0.10559200811463	1.13703460085795	2.24092198543993	1.72432276431446	0.629173857511188	0.507395888052183	0.659409377634706	0.163423529738371	NA	NA	0.473081669853872	0.332450987759182	69.9102928335229
a2219	loss_cnaOV39	1023	GW 441756	NTRK1	10	21	0.693147180559945	NA	1.8369879815404	2.51822133011714	-0.68123334857674	1.52870894288013	1.05834011503086	0.55664563666946	0.445626586898403	0.643680929128228	0.163647386573415	NA	NA	0.840054610643619	0.22537727130022	69.9604829183501
a2220	gain_cnaOV49	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.37026136567954	4.96887353364844	-0.598612167968908	0.780169976630402	0.852701328957822	0.705995175143766	0.767284291756968	0.702018570441935	0.163688321919824	NA	NA	0.14301471086256	0.313635573724334	69.9604829183501
a2221	gain_cnaOV96	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.83914660372957	2.2132208890298	0.625925714699772	0.719622058339749	0.898832100014328	0.709679721269099	0.869797843806865	0.696376681128538	0.163779387833527	NA	NA	0.5837763491275	0.183836684497418	69.9678874758041
a2222	gain_cnaOV72_(ASXL1)	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.6254762408188	4.84184762498071	0.78362861583809	1.26520421207459	1.20406565908909	0.646347287376528	0.619369275220124	0.650818840254048	0.163899411238401	NA	NA	0.359527975250403	0.251962236462439	69.9776465579996
a2223	loss_cnaOV70	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	7.86951622294929	8.84387459801728	-0.97435837506799	0.546224969824245	1.24463971448018	0.805593793903806	1.78380416292851	0.782843712708401	0.164184945539533	NA	NA	0.518141587307601	0.0588108963142482	69.9776465579996
a2224	BRCA1_mut	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	3.71813738716858	1.86849938470175	1.84963800246683	0.760693702785118	1.98241230330118	0.96073252531547	2.43151480772717	0.933023871667233	0.164306736590147	NA	NA	0.122364221496728	0.0198003543928617	69.9776465579996
a2225	loss_cnaOV33_(ZFHX3)	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	0.0656851968256531	-1.51498251959856	1.58066771642422	1.73321555809868	1.81658921459003	0.874057739640706	0.911985649470048	0.87012941821354	0.164313166611305	NA	NA	0.0668067070957447	0.165093278173408	69.9776465579996
a2226	loss_cnaOV38	1149	TW 37	BCL2, BCL2L1	8	25	1.6094379124341	NA	-0.239170717722173	-0.900783363999947	0.661612646277773	1.184094206257	0.774862520379826	0.748441349478323	0.558750007205233	0.853845203344538	0.164373837419242	NA	NA	0.0370494976503903	0.172456430335004	69.9776465579996
a2227	loss_cnaOV55	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	7	25	0.246860077931526	2.32630161961136	0.259789241857846	1.21260653004253	-0.952817288184687	0.938985437886947	1.61947596005961	0.631781052415374	1.01473063344717	0.588349139896843	0.164416562444094	NA	NA	0.785313924724125	0.0635864221782839	69.9776465579996
a2228	loss_cnaOV83	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	5	26	2.30258509299405	NA	2.31985066873029	1.23386617826142	1.08598449046887	2.75613297282233	1.0608972717643	0.764470313083782	0.394024708233437	1.02364717053411	0.164421100221187	NA	NA	0.463883089155	0.431483758432898	69.9776465579996
a2229	gain_cnaOV19	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.98088986285182	4.85912405137993	1.12176581147189	0.76861836131721	1.22598367102138	0.934085578821335	1.45945747321139	0.914992457067013	0.164447628112798	NA	NA	0.359569753155461	0.105109619658482	69.9776465579996
a2230	gain_cnaOV96	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	2.11670622766645	1.03700045530932	1.07970577235714	0.893184427729898	1.50849483726856	0.739360478022456	1.20882735842283	0.715750392830094	0.16456874135873	NA	NA	0.808138927724576	0.0886861453550992	69.9776465579996
a2231	loss_cnaOV34	1025	SB 216763	GSK3A, GSK3B	4	19	2.30258509299405	NA	4.49361569954854	5.05813299842586	-0.564517298877315	1.47033584763104	0.628129649255495	0.701805922578409	0.383937656003455	0.898727355962933	0.164690972389464	NA	NA	0.436038196623655	0.502222174061152	69.9776465579996
a2232	loss_cnaOV58	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.72612473986992	1.79364410741045	0.932480632459463	0.794514897662108	1.36895199283098	0.713435025898419	1.17364776318647	0.681163866477965	0.164696992674178	NA	NA	0.834626150660282	0.063672487712066	69.9776465579996
a2233	loss_cnaOV82	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.94274510556238	2.22447553935842	0.718269566203966	0.957289659288184	0.87544924033453	0.814976813562951	0.750315810094567	0.820458266580365	0.164978294962977	NA	NA	0.583851066355294	0.321953501567162	69.9776465579996
a2234	gain_cnaOV48_(SOX17)	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-1.04604334358058	-0.011159223512675	-1.0348841200679	1.40681145694709	1.2162678246878	0.841125404775697	0.735623892567449	0.850868615498849	0.165005663980881	NA	NA	0.760623899873853	0.329525449330404	69.9776465579996
a2235	TP53_mut	1248	FK866	NAMPT	22	10	0	NA	-1.34642707427099	-2.50460523416316	1.15817815989217	2.69074921167414	2.8021878965087	0.425072633236063	0.430429619701187	0.413312098498165	0.165007952285943	NA	NA	0.0393350094772893	0.287998644383381	69.9776465579996
a2236	loss_cnaOV82	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	7.87159998982588	8.8436513372805	-0.972051347454622	0.548910330118951	1.24473323686578	0.803571127243621	1.77087457480346	0.780931462794575	0.165152929173302	NA	NA	0.518208407829301	0.0601165820454105	69.9776465579996
a2237	loss_cnaOV36	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.30815566571897	2.18514799886875	1.12300766685022	1.60283637744021	1.36317940237627	0.813158912806499	0.700637746095896	0.823815020159937	0.165181083679414	NA	NA	0.518210566324215	0.348372698274104	69.9776465579996
a2238	loss_cnaOV54	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	11	22	-1.38629436111989	0.693147180559945	-1.59948678520984	-2.64763849647398	1.04815171126413	1.5568773895792	1.54214803699853	0.677575607277194	0.673239728625922	0.67966997079226	0.165188837907479	NA	NA	0.114918631555387	0.0824181115139628	69.9776465579996
a2239	loss_cnaOV42	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.94861542186631	4.32148244639725	0.627132975469054	1.36859334695384	0.763702197802284	0.745288267706813	0.458231787305484	0.821174768481435	0.165216941925955	NA	NA	0.866050725607006	0.430764594153077	69.9776465579996
a2240	loss_cnaOV39	1033	Vismodegib	SMO	10	21	2.30258509299405	NA	5.29900380321535	4.72615261938293	0.572851183832421	0.896795947186827	0.786091566461782	0.696861025038042	0.638775393253512	0.728733404952859	0.165229275774517	NA	NA	0.143113400794537	0.103361608966996	69.9776465579996
a2241	loss_cnaOV82	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.19511138351593	2.66647633014377	0.528635053372164	0.912574263281675	0.516286848128745	0.958305469886262	0.579278941607621	1.02391733449762	0.165277263044308	NA	NA	0.125466278559929	0.42197206606288	69.9776465579996
a2242	loss_cnaOV33_(ZFHX3)	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	0.113025191260318	-1.22691013446925	1.33993532572957	2.23995690601802	1.89945573194709	0.692043019923093	0.5981969216147	0.705431194416954	0.165388801424095	NA	NA	0.431157676483568	0.323890322508248	69.9924278070187
a2243	loss_cnaOV39	275	I-BET	BRD2, BRD3, BRD4	9	22	2.99573227355399	NA	3.41838114385237	4.12500696164404	-0.706625817791668	1.15667338902652	1.19729786234081	0.595690355658211	0.610912142092575	0.590183813082369	0.165459708547341	NA	NA	0.690544869597424	0.146720668752546	69.9924278070187
a2244	loss_cnaOV35	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.82569467327072	4.17650424278687	0.649190430483855	1.0942478446928	0.829906348758691	0.7463623718226	0.5932754938769	0.782245408117269	0.165568743529847	NA	NA	0.510140322126583	0.264088814916487	70.0073400867739
a2245	ARID1A_mut	1243	piperlongumine	Increases ROS levels	9	23	2.30258509299405	NA	1.25277990888719	1.75600679094074	-0.503226882053546	0.665001035089249	0.642426035501157	0.775958566689347	0.756730975593156	0.78332267723393	0.165680724323238	NA	NA	0.197044704765214	0.0720866721612777	70.0234841024096
a2246	gain_cnaOV96	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.98044721681113	2.30968853190013	0.670758684910999	1.15526196280685	0.89271846514357	0.72723428972823	0.580611762964401	0.7513664286121	0.165852791547345	NA	NA	0.727757827788793	0.335066291055765	70.0445202140638
a2247	loss_cnaOV84	1049	PD-173074	FGFR1, FGFR3	6	27	0.693147180559945	NA	3.6016079718503	2.84982146066713	0.751786511183173	0.899396817108486	0.982086208011821	0.775656176403517	0.835878554251646	0.76549951017551	0.165987322721437	NA	NA	0.0799475679488538	0.106678290177091	70.0445202140638
a2248	loss_cnaOV81_(RB1)	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.0413943410978141	-0.836805947496028	0.795411606398213	1.40970394810499	0.817041622628381	0.891937512992903	0.564240177852557	0.973526420648454	0.166033925896593	NA	NA	0.0370946144162508	0.344153866906157	70.0445202140638
a2249	gain_cnaOV72_(ASXL1)	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	6.05202831775451	5.4436934804414	0.608334837313109	0.693299188637176	0.996780487794941	0.632453659533566	0.877449227236105	0.610299704661009	0.166080887478188	NA	NA	0.291246418599381	0.136391777543957	70.0445202140638
a2250	ARID1A_mut	207	AS601245	JNK 	5	13	2.07944154167984	NA	1.71838368757394	2.09927319278245	-0.380889505208513	1.23720756194294	0.887254063962604	0.386121080682694	0.30786225118957	0.429290234532605	0.166260488687013	NA	NA	0.455939114248424	0.55384842473917	70.0445202140638
a2251	RB1_mut	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	3.18234665125862	2.45227210531168	0.730074545946943	0.247632645040718	1.05927442170084	0.713740112348339	2.94821607961623	0.689221349057675	0.166419355600102	NA	NA	0.18312725051295	0.0109533068482521	70.0445202140638
a2252	loss_cnaOV59	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.41073327239995	5.8832899105189	0.527443361881046	0.798057249670176	0.672495047497668	0.769258216121562	0.660909179258793	0.784308172742156	0.166492674828788	NA	NA	0.906275900372256	0.282436848442204	70.0445202140638
a2253	PIK3CA_mut	273	CUDC-101	HDAC, EGFR	6	25	1.63315443905142	NA	-0.336088930195918	0.227073145879675	-0.563162076075593	0.92112993203306	1.73123787209059	0.347477468852895	0.611381800212069	0.325294452688663	0.166578285640907	NA	NA	0.449290621284532	0.288131091365896	70.0445202140638
a2254	loss_cnaOV54	269	NSC-207895	MDM4	10	21	2.99573227355399	NA	4.48667993863445	3.59844058094981	0.888239357684646	1.67352040298467	1.4845021727591	0.574674643980676	0.530760997057758	0.598341567957264	0.166598758469588	NA	NA	0.707852416656313	0.171530116033909	70.0445202140638
a2255	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.37584289054507	0.64389800811218	0.73194488243289	0.483512779616967	1.07944727297843	0.717380390328151	1.51380669402932	0.678073770489311	0.166614495024866	NA	NA	0.76582861404095	0.0296128678537519	70.0445202140638
a2256	loss_cnaOV43_(NF1)	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	6.11443530151981	5.6546297357434	0.459805565776409	0.904130593848472	0.518092233226462	0.786683602410295	0.508561007563328	0.887497507756354	0.16666964629462	NA	NA	0.18072523516567	0.325074134024254	70.0445202140638
a2257	gain_cnaOV96	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-1.83247545598388	-2.45785017542298	0.625374719439095	0.703777228617681	0.719870362208684	0.872141309140784	0.888597547646462	0.868732416653937	0.166825133419031	NA	NA	0.658700098375527	0.178954607735054	70.0445202140638
a2258	loss_cnaOV40	173	FH535	unknown 	4	14	3.46573590279973	NA	3.12812293344852	2.31645594626596	0.811666987182562	1.54775068563976	1.38383354106247	0.573205439997359	0.524417139474281	0.586535130922889	0.166876684694635	NA	NA	0.103539523887248	0.392250811441544	70.0445202140638
a2259	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	4.15395753970347	3.18538745578748	0.968570083915992	0.720148898059172	1.02606474906047	0.960348249143254	1.34495808648229	0.943965850890866	0.167030931168248	NA	NA	0.0837418122374577	0.126953869706559	70.0445202140638
a2260	loss_cnaOV57_(ZNRF3)	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-3.22306655100212	-4.32064156147157	1.09757501046945	2.81534747150803	0.994689435859719	0.846021207157116	0.389854190851097	1.10343487213253	0.167232036186828	NA	NA	0.205675549478921	0.494126691271201	70.0445202140638
a2261	loss_cnaOV83	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.86326407883067	4.11612096046386	0.747143118366818	1.0204917152469	0.935372670428396	0.789136317587776	0.732140307661439	0.798765178829343	0.16725912596841	NA	NA	0.19805762913298	0.184404615462282	70.0445202140638
a2262	KRAS_mut	1021	Axitinib	PDGFR, KIT, VEGFR	6	24	0.693147180559945	NA	1.91012996975548	2.6790669574441	-0.768936987688624	1.36025958180294	0.900381302191105	0.770350779522358	0.565286948149593	0.854012612009371	0.167316245744045	NA	NA	0.183191808385429	0.235636139120691	70.0445202140638
a2263	gain_cnaOV72_(ASXL1)	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	3.20736444491048	2.11929828419614	1.08806616071433	1.53816907334328	1.7902469559732	0.618306893076755	0.70737747856897	0.60777433922397	0.167333566230365	NA	NA	0.101789867609905	0.204691080990804	70.0445202140638
a2264	RB1_mut	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	9.61730844719685	8.65661114541932	0.960697301777525	0.359283948509368	1.25072779088783	0.79362917269477	2.67392213251764	0.768110622292619	0.167361345193391	NA	NA	0.51835917179325	0.013034073503289	70.0445202140638
a2265	loss_cnaOV85	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	NA	0.555715103896271	1.39384436789443	-0.838129263998161	1.68022603694874	1.04937688352986	0.699784589934053	0.49881935261531	0.798692326039135	0.167470552829903	NA	NA	0.254739630430613	0.247964246827634	70.0445202140638
a2266	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.46689288057318	0.192681451879208	1.27421142869398	1.46316097628836	1.6493283158067	0.78121901842934	0.870862091966325	0.772563847041425	0.167471245439904	NA	NA	0.83264971523699	0.181645926490096	70.0445202140638
a2267	loss_cnaOV59	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.45338263145453	2.77050267043278	0.682879961021752	1.52123868540446	0.990683724952336	0.646785677568247	0.448897314782781	0.689301685111065	0.167492086841642	NA	NA	0.293969851867604	0.440959845175253	70.0445202140638
a2268	loss_cnaOV38	257	NPK76-II-72-1	PLK3	8	24	2.32630161961136	NA	2.75977456140554	3.38634105538549	-0.626566493979944	1.39630935828635	1.14607389133372	0.518207588277475	0.4487304265789	0.546706890993555	0.167494623041079	NA	NA	0.591023589514246	0.277258616054751	70.0445202140638
a2269	loss_cnaOV54	265	Tubastatin A	HDAC6	10	21	2.99573227355399	NA	5.11493435419626	4.58549296446281	0.529441389733451	1.0064006054996	1.29351442901323	0.436936461306984	0.526074196339164	0.409304587454306	0.167522138858261	NA	NA	0.411968698057261	0.226106220527558	70.0445202140638
a2270	loss_cnaOV58	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.46433244024626	4.98749942565987	0.476833014586391	0.43231353291759	0.617827146720773	0.799471562435546	1.10297961613264	0.771790325364087	0.167753558393053	NA	NA	0.101552681100139	0.0714713630911563	70.0445202140638
a2271	loss_cnaOV56	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	5.18028456345887	4.3051811297184	0.87510343374047	0.895327248597366	0.962322569132055	0.913467244391847	0.977411817982108	0.909366008665628	0.167758741228554	NA	NA	0.500067468045659	0.225386408797211	70.0445202140638
a2272	SMAD4_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.24835125463408	2.21915791039569	1.02919334423839	1.77628170697565	1.49770601973806	0.674046449577533	0.579408851758499	0.687179814112244	0.167831253092679	NA	NA	0.230211510517584	0.336920937016041	70.0445202140638
a2273	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.53708189687846	2.72394466779756	0.8131372290809	1.21183182626015	0.917797825350508	0.86545510329949	0.67099841039027	0.885965521622763	0.16785441342771	NA	NA	0.965300360266679	0.364994833317179	70.0445202140638
a2274	gain_cnaOV72_(ASXL1)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	0.483564071076256	-0.478304282017952	0.961868353094208	0.216626691904024	1.46921583482641	0.700375201231425	4.44021161307473	0.654681449991213	0.167871336700072	NA	NA	0.886057340182625	0.00263786898369042	70.0445202140638
a2275	loss_cnaOV59	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	5.18114756103492	4.34734020314176	0.833807357893164	1.18210344964843	0.921281874545196	0.877147311955626	0.705359042934144	0.905051299641367	0.16800331514292	NA	NA	0.0272807407477704	0.255923520365733	70.0522207441258
a2276	ARID1A_mut	1021	Axitinib	PDGFR, KIT, VEGFR	9	21	0.693147180559945	NA	1.97786629358734	2.75988524547168	-0.782018951884332	1.22085605183615	0.864831879838754	0.798106158498096	0.640549678816097	0.904243900016889	0.168204761259491	NA	NA	0.183255381672319	0.107701121080135	70.0522207441258
a2277	loss_cnaOV56	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.44020933064259	-4.77804273420924	1.33783340356665	2.06923005036088	1.30730263191398	0.974041717137633	0.64653681369712	1.0233540198783	0.16823098146168	NA	NA	0.125135301292327	0.379299154168708	70.0522207441258
a2278	gain_cnaOV48_(SOX17)	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	-1.05997640817838	0.877817220138707	-1.93779362831709	2.06664829421794	2.26840323833177	0.859135989436812	0.937650413831245	0.854254479790897	0.168232777823854	NA	NA	0.944361561053422	0.239482226305152	70.0522207441258
a2279	SMARCA4_mut	310	YM201636	FYV1	3	29	1.63315443905142	NA	1.74974520239305	2.41972740287034	-0.669982200477286	0.455936227546726	0.872662260634326	0.787055783568881	1.46946471896363	0.767745129702625	0.168382905563046	NA	NA	0.641716253081646	0.100360738453182	70.0522207441258
a2280	loss_cnaOV20	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.58179267173146	3.77961601472336	0.802176657008096	1.10797570787167	1.0318660341454	0.769843932629964	0.724002025774563	0.77740387847194	0.168403710059644	NA	NA	0.304043095254381	0.188885127810226	70.0522207441258
a2281	loss_cnaOV44	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.19199557837797	2.66679865481321	0.525196923564758	0.913883745739952	0.516462080036502	0.951559608009014	0.574686797979449	1.01691284581365	0.168530987160094	NA	NA	0.125652835387639	0.425073691428689	70.0522207441258
a2282	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1028	VX-702	p38	3	28	0.693147180559945	NA	4.0745312145522	3.24687329382185	0.827657920730349	0.86456325938836	0.901097602266868	0.92102633986688	0.957313315992493	0.918499748138527	0.168542291205171	NA	NA	0.506410758507784	0.232543918081897	70.0522207441258
a2283	loss_cnaOV38	1009	ATRA	Retinoic acid and retinoid X receptor agonist	8	23	2.30258509299405	NA	4.84198213750007	4.39677180900254	0.445210328497535	1.07392342012273	0.84792408889479	0.490512830005581	0.41456431637058	0.525059181981533	0.168722475286459	NA	NA	0.51692711610944	0.312285517494783	70.0522207441258
a2284	loss_cnaOV85	166	FTI-277	Farnesyl transferase (FNTA)	6	13	0.0237165266173161	NA	2.87255316536876	2.24830712575396	0.624246039614798	0.860953118215145	0.781141994424836	0.775039964544932	0.725063916266349	0.799145410271327	0.16872569146324	NA	NA	0.604462981802265	0.164919655721317	70.0522207441258
a2285	loss_cnaOV35	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.47594401663992	5.75935663844482	-0.283412621804897	0.73285236860033	0.415102048197334	0.60294449323964	0.386725395110866	0.682754091519602	0.168790365543522	NA	NA	0.369068070130698	0.443273942755157	70.0522207441258
a2286	loss_cnaOV81_(RB1)	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	4.10620867000477	2.85321533830843	1.25299333169634	0.692222865434967	1.64847859699561	0.793470791160049	1.81010104442159	0.760090749118583	0.168892236237691	NA	NA	0.654909634957593	0.024391457612717	70.0522207441258
a2287	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.38350208284134	5.74937389905813	-0.365871816216782	0.369429385312374	0.475481347788361	0.779848375230919	0.990370097136198	0.769476695392125	0.168979127935523	NA	NA	0.369081955815782	0.219650268183583	70.0522207441258
a2288	loss_cnaOV34	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.82174740283408	4.17723521879366	0.644512184040426	1.09821595171238	0.82969158975715	0.740567441775982	0.586871992740117	0.776809349398219	0.168991499067493	NA	NA	0.510366686257115	0.268550070014849	70.0522207441258
a2289	loss_cnaOV52, loss_cnaOV53	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	9	24	-1.38629436111989	0.693147180559945	-1.51783664561118	-2.5909113228848	1.07307467727362	1.72769849428747	1.48647976437647	0.691270520687629	0.621100661267968	0.721889865566881	0.169016761470311	NA	NA	0.115121856195908	0.123721659132748	70.0522207441258
a2290	loss_cnaOV83	1028	VX-702	p38	5	26	0.693147180559945	NA	3.89220693261084	3.21826966183132	0.673937270779519	0.656677131854392	0.930482000847016	0.750742161088861	1.02628405663585	0.724288347508103	0.169073030150217	NA	NA	0.506446924107306	0.0894856015623465	70.0522207441258
a2291	loss_cnaOV83	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	3.15491181501369	2.80985168316234	0.345060131851349	0.784286440721863	0.801846461730791	0.431580115855246	0.439966973716584	0.430331925524164	0.169303812844539	NA	NA	0.0166825562164245	0.404505670270856	70.0522207441258
a2292	PTEN_mut	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	-0.867562489518399	0.000728209962109809	-0.868290699480509	1.71464887890357	1.16610642087282	0.703519291524933	0.506395630127923	0.744606739092135	0.169824927248568	NA	NA	0.760805962589445	0.39125506072568	70.0522207441258
a2293	TP53_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	12	7	2.77258872223978	NA	5.31833124564345	4.54047463761803	0.777856608025424	1.10659337023927	1.18346605127563	0.685747102332658	0.702929033324347	0.657269895648458	0.169868766312269	NA	NA	0.790981254797944	0.182487826456403	70.0522207441258
a2294	loss_cnaOV56	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.16218975765928	0.585811679001359	0.576378078657922	0.835222704887825	0.576954446637557	0.964399815588758	0.690089092747225	0.999001016487534	0.170045051241072	NA	NA	0.0128049470090585	0.354071665623903	70.0522207441258
a2295	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	8	23	-1.6094379124341	NA	1.09197810499282	0.382655041098285	0.70932306389453	1.11499003478908	1.19972216597793	0.601209452822747	0.636169868575295	0.59123944193891	0.170208184378736	NA	NA	0.418272194406256	0.152460125476963	70.0522207441258
a2296	loss_cnaOV42	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	2.01792870934822	3.03209353411211	-1.01416482476389	0.622328811683319	1.25780002608332	0.838586979695999	1.62962859138838	0.806300527693512	0.17028912030571	NA	NA	0.219553401110403	0.034881678710622	70.0522207441258
a2297	gain_cnaOV26	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.97422927253586	0.730835272874402	1.24339399966146	2.99043067097243	1.09769585570952	0.952479135979479	0.415790946678972	1.13273088642369	0.170349775953019	NA	NA	0.152963725164335	0.546910015204669	70.0522207441258
a2298	loss_cnaOV58	1026	17-AAG	HSP90	5	28	0	NA	-1.43930390158221	-0.368605061273592	-1.07069884030861	2.09980128128921	2.30715348318811	0.469304737920958	0.509904841876866	0.464077855292524	0.170449437987719	NA	NA	0.0551981098646222	0.341778163620456	70.0522207441258
a2299	loss_cnaOV84	288	KIN001-055	JAK3, MNK1	6	26	2.32630161961136	NA	4.34585387051308	3.67524941541172	0.670604455101364	1.06465595576438	0.991330353830557	0.667983770864613	0.62987902474081	0.676469203742334	0.170477075855121	NA	NA	0.709923024885738	0.201012636539346	70.0522207441258
a2300	loss_cnaOV85	206	Ruxolitinib	JAK1, JAK2, TYK2	7	25	1.65632149833295	0.0237165266173161	4.73666946476072	4.37220818306819	0.364461281692523	0.587573422080284	0.526200818810947	0.676137028010439	0.620282109429253	0.692627735768435	0.170636580739623	NA	NA	0.352264739811732	0.172645949928746	70.0522207441258
a2301	loss_cnaOV39	1143	HG-5-88-01	EGFR, ADCK4	7	15	2.30258509299405	NA	3.82732206282861	3.52778542074144	0.299536642087177	0.835453129969551	0.932653884922872	0.331129365398954	0.358531952711811	0.321165919028952	0.170683475619305	NA	NA	0.0507637326564066	0.464016970219087	70.0522207441258
a2302	loss_cnaOV83	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.36350470615587	2.76185488026506	0.601649825890812	1.4838740553125	0.975453761098752	0.568956336319625	0.405458821614146	0.6167896930482	0.170762358233729	NA	NA	0.294210813184861	0.425638612189142	70.0522207441258
a2303	PIK3CA_mut	208	SB-715992	KIF11	6	26	-2.05572501506252	NA	-2.74939986195969	-0.986937330373039	-1.76246253158665	1.5996322351304	1.77673401596521	1.00800662907603	1.10179233256261	0.991967574071122	0.170826290390078	NA	NA	0.0670704388870128	0.0440241323146826	70.0522207441258
a2304	gain_cnaOV51_(MYC)	286	KIN001-236	TIE2	8	24	2.32630161961136	NA	5.08499100624723	4.69843059591493	0.386560410332305	0.567387989165679	0.669369888141879	0.597453417806494	0.681298190504044	0.577498954136357	0.17087343013769	NA	NA	0.75590496312936	0.133433480937004	70.0522207441258
a2305	loss_cnaOV56	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	5.0567867904607	3.61679188757432	1.43999490288638	0.936292860713087	1.54595825086249	0.951087142393323	1.5379748829759	0.931457820470252	0.17089266607931	NA	NA	0.154815145889972	0.0932695728649277	70.0522207441258
a2306	PTEN_mut	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.13404164902504	2.89075892542165	0.243282723603386	0.283174593714817	0.897504183139935	0.283494102735314	0.859126238734519	0.271065838102566	0.170974792170503	NA	NA	0.311616068782894	0.369136466910178	70.0522207441258
a2307	loss_cnaOV16, loss_cnaOV17	1259	BMN-673	PARP1	6	27	2.30258509299405	NA	2.75771759300699	1.70989139484409	1.0478261981629	0.956718283861309	1.38683956385616	0.789662486662418	1.0952296154871	0.755549686835713	0.171221425039417	NA	NA	0.0301794974038663	0.0503113804905977	70.0522207441258
a2308	loss_cnaOV57_(ZNRF3)	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	5.00818721798227	4.41821638356693	0.589970834415346	0.768651481673334	0.666780909981983	0.871050819034384	0.767540099097962	0.884804627102008	0.171373312826409	NA	NA	0.0742442077702653	0.224307862757641	70.0522207441258
a2309	loss_cnaOV34	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.99237688096617	3.65989900966781	-0.667522128701644	0.987955045811152	0.926416735852513	0.714037439026922	0.675660427599296	0.720541957920668	0.171384961287997	NA	NA	0.721501787779216	0.21609560469217	70.0522207441258
a2310	loss_cnaOV54	271	VNLG/124	HDAC, RAR 	10	21	1.63315443905142	NA	4.576938965388	4.21145746237627	0.365481503011732	0.500225444936379	0.592427924081458	0.646384086695552	0.730633570745718	0.616921465304661	0.171456352987058	NA	NA	0.241370072221735	0.08815149063484	70.0522207441258
a2311	loss_cnaOV57_(ZNRF3)	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.72662891041804	2.9769914141216	0.749637496296449	0.971553683949577	0.882050969239465	0.841244385264752	0.771586283579317	0.849880021040975	0.171477424679364	NA	NA	0.227213520905966	0.222711820971487	70.0522207441258
a2312	RB1_mut	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	2.11035782327712	3.07412512664276	-0.96376730336564	0.765488335800816	0.985949026590109	0.990273002896447	1.25902284632122	0.977502160227102	0.171551594451034	NA	NA	0.0801880008223079	0.146297124946962	70.0522207441258
a2313	loss_cnaOV52, loss_cnaOV53	260	NG-25	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	3.39917448356008	2.88291748329035	0.516257000269731	0.955048026334508	1.09768189299566	0.484244159805568	0.54055606213976	0.47031567484531	0.171638218430694	NA	NA	0.422461254675152	0.223848245824384	70.0522207441258
a2314	loss_cnaOV59	306	TG101348	JAK2	4	28	2.32630161961136	NA	3.76631244722943	2.68945092838873	1.0768615188407	1.01753105867895	1.39236549642868	0.792077540032525	1.05830825472666	0.773404340744419	0.171649738107099	NA	NA	0.618301181039116	0.121517958182527	70.0522207441258
a2315	loss_cnaOV81_(RB1)	1030	KU-55933	ATM	4	29	2.30258509299405	NA	4.85820197615385	4.0534489197482	0.804753056405652	0.738491714779903	1.02648325186818	0.80295734262591	1.08972523360739	0.78399044011777	0.171656997866752	NA	NA	0.519168740401899	0.113251183467831	70.0522207441258
a2316	loss_cnaOV56	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.63515953585879	4.83334872970067	0.801810806158126	0.806923368397629	0.833904049148453	0.963632214332279	0.993664129160548	0.961514465575386	0.171708582604131	NA	NA	0.143517445372146	0.22005244219352	70.0522207441258
a2317	loss_cnaOV84	1036	PLX4720	BRAF	6	27	2.30258509299405	NA	5.04605941364718	4.14385307449251	0.902206339154673	1.01017613567361	1.31509896857708	0.709909045241824	0.893117850733093	0.686036838832632	0.171723460437439	NA	NA	0.359021364696592	0.0943203542612071	70.0522207441258
a2318	loss_cnaOV38	1230	IOX2	EGLN1	8	24	-2.30258509299405	NA	-0.503692448296043	0.0834072681861874	-0.587099716482231	1.30171675286448	0.792231757874496	0.627077464340914	0.451019559508851	0.74107066606037	0.171787605583742	NA	NA	0.53836909015631	0.260162648727911	70.0522207441258
a2319	loss_cnaOV20	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-3.57818069385657	-4.94100813189886	1.36282743804229	3.05382649696422	1.69558956965711	0.680274688968852	0.446268784227611	0.803748420272415	0.171865518214459	NA	NA	0.326965444076438	0.445548599603562	70.0522207441258
a2320	gain_cnaOV96	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	2.21840585447506	0.899489460969738	1.31891639350532	1.60271811660425	1.47439182544645	0.880547493654317	0.82292474256157	0.894549447943357	0.171871486482412	NA	NA	0.514617417694056	0.204143308737592	70.0522207441258
a2321	loss_cnaOV58	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.4063269445097	3.68888790004573	0.717439044463969	1.25278254917058	0.960345888002572	0.714388849319185	0.572676435299133	0.747063171120745	0.171902189232285	NA	NA	0.709983424772582	0.279173725853939	70.0522207441258
a2322	loss_cnaOV84	1053	MK-2206	AKT1, AKT2	6	26	1.38629436111989	0.693147180559945	2.04526285793395	1.14019051505893	0.905072342875029	1.10989124418626	1.1845723169997	0.771945771848064	0.815460386426062	0.764049885250911	0.171915742031257	NA	NA	0.0892763584560999	0.114030717807962	70.0522207441258
a2323	TP53_mut	1378	Bleomycin (50 uM)	DNA damage	22	10	3.91202300542815	NA	2.33976281279808	1.38661124362988	0.953151569168206	2.00110172530092	1.83057174239844	0.488417961622602	0.476313401321401	0.520685175615882	0.172025128783717	NA	NA	0.122798038592854	0.200714216957392	70.0522207441258
a2324	loss_cnaOV33_(ZFHX3)	306	TG101348	JAK2	4	28	2.32630161961136	NA	3.7654618401948	2.68957244367939	1.07588939651541	1.09854001378696	1.38560680253391	0.791310241403797	0.979381163191796	0.776475255857498	0.1720706593599	NA	NA	0.618323657315071	0.143862307798921	70.0522207441258
a2325	ARID1A_mut	1019	Bosutinib	SRC, ABL, TEC	9	22	0.693147180559945	NA	0.678605404994755	2.15095055265924	-1.47234514766448	1.25393146123457	1.52725635779949	1.01054117981587	1.17418311381618	0.964045846098735	0.172130293029334	NA	NA	0.0362973771878064	0.0123335088433436	70.0522207441258
a2326	KRAS_mut	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	4.50535274537933	3.74908809304937	0.756264652329956	1.23737959155178	1.17418135804828	0.636836838727149	0.611182419278092	0.644078231310892	0.172288349159213	NA	NA	0.690867465597602	0.182597762692462	70.0522207441258
a2327	loss_cnaOV58	281	CH5424802	ALK	5	27	1.63315443905142	NA	4.34105511906284	3.85104093996407	0.490014179098766	0.572945659554531	0.731403322353023	0.687917624891056	0.855254195449801	0.669964387804972	0.172358645351331	NA	NA	0.954610850515963	0.139633622622467	70.0522207441258
a2328	loss_cnaOV1	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.92448045036787	2.7102218769896	1.21425857337826	1.00445630626022	1.38206323883463	0.892735581360716	1.20887147187037	0.8785839455524	0.172381150412687	NA	NA	0.618340195718945	0.156165968465184	70.0522207441258
a2329	ARID1A_mut	1175	AG-014699	PARP1, PARP2	9	24	1.6094379124341	NA	3.38427866542752	4.09498765758599	-0.71070899215847	0.790759420340126	1.10492985490691	0.687977231534376	0.898767657870931	0.643216389712222	0.172456657231228	NA	NA	0.304329955009236	0.0536903331687589	70.0522207441258
a2330	gain_cnaOV18_(CCNE1)	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	2.98495583361492	1.31519228428943	1.66976354932549	1.02427358767165	2.42264688679858	0.745354748550438	1.63019291859428	0.689231087875132	0.172549136308945	NA	NA	0.596012440658301	0.0600673643968277	70.0522207441258
a2331	gain_cnaOV95_(MECOM)	1021	Axitinib	PDGFR, KIT, VEGFR	7	23	0.693147180559945	NA	3.00390570441239	2.37961073331759	0.624294971094794	1.09520063602186	0.987351224164808	0.617239679430351	0.570027947904087	0.632292699715727	0.172561202093717	NA	NA	0.183561716695261	0.20924034049408	70.0522207441258
a2332	NF1_mut	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-5.133382094656	-4.04773934094958	-1.08564275370642	0.465471879553032	1.3599253851968	0.8360691801857	2.33234874413661	0.798310529036351	0.172698225665971	NA	NA	0.206048484050138	0.00816807346711098	70.0522207441258
a2333	loss_cnaOV87, loss_cnaOV88	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	1.88265729578328	3.0111159277649	-1.12845863198163	0.686403374707331	1.24029047786732	0.931632378147666	1.64401673063274	0.909834149434097	0.172715481091198	NA	NA	0.219720247555912	0.0775529404970418	70.0522207441258
a2334	loss_cnaOV38	1129	PF-4708671	RPS6KB1 (p70S6KA)	8	24	2.30258509299405	NA	4.70221954045391	4.02863489676907	0.67358464368484	1.29113735634055	0.79479052392419	0.720804296933744	0.521698671622336	0.847499590658291	0.172728619384021	NA	NA	0.0428476199948965	0.198428824025053	70.0522207441258
a2335	loss_cnaOV41	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.5847919320366	5.71346923099588	0.871322701040717	0.510273841038106	1.31999543983598	0.690095798374407	1.70755902216757	0.660095235744894	0.172752129103103	NA	NA	0.56081643343252	0.0338370182176754	70.0522207441258
a2336	gain_cnaOV49	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	2.15977267891491	3.80007340257711	-1.6403007236622	2.00560497725705	1.9818110167507	0.827012013810061	0.817858323180639	0.827677669463948	0.172880022050279	NA	NA	0.740940473573803	0.289272413897945	70.0522207441258
a2337	gain_cnaOV48_(SOX17)	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	2.06225969902765	3.51091224800114	-1.44865254897348	1.80639392176768	1.61134193655466	0.89143794051636	0.801958272510061	0.899034845497143	0.172902901419587	NA	NA	0.620728258012273	0.296779467793332	70.0522207441258
a2338	gain_cnaOV94	328	SNX-2112	HSP90	7	25	0.940007258491471	NA	1.75584056108892	0.399435449274596	1.35640511181433	2.62968092807399	2.15325780552876	0.601082585508338	0.515805966166311	0.629931589395187	0.172940162198488	NA	NA	0.944401826279429	0.24427263596469	70.0522207441258
a2339	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	-1.38629436111989	0.693147180559945	-2.68113039492732	-1.94515839504419	-0.735971999883138	1.53456484393578	1.17135140543365	0.582932370125811	0.479596546728877	0.628310169321625	0.172971996837386	NA	NA	0.598402087987317	0.242081363880987	70.0522207441258
a2340	loss_cnaOV87, loss_cnaOV88	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	2.90483440657801	3.7617915623596	-0.856957155781583	0.424915319072309	1.05992156218888	0.832124704354649	2.01677161852513	0.808509975032351	0.173014409015659	NA	NA	0.826566983225289	0.0394948034063768	70.0522207441258
a2341	gain_cnaOV96	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	2.00549521632673	0.453677558439025	1.55181765788771	2.74509025499465	2.17085567372796	0.687898536113651	0.565306606973742	0.714841468582203	0.173035343832705	NA	NA	0.944402627102195	0.285383282812088	70.0522207441258
a2342	gain_cnaOV49	333	T0901317	LXR	3	29	2.32630161961136	NA	4.21576693178862	4.80896397412858	-0.593197042339962	0.572258102490207	1.14353900700189	0.532205890976256	1.03659002774908	0.518737916859692	0.173117225066875	NA	NA	0.00417502390417984	0.206427527979012	70.0522207441258
a2343	TP53_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	22	10	2.99573227355399	NA	4.29328766306155	3.45937481850654	0.833912844555007	1.436492181856	1.5012642303688	0.572653319407856	0.580520280644733	0.555473731862743	0.17313215417836	NA	NA	0.31727506521808	0.158420648465847	70.0522207441258
a2344	loss_cnaOV34	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	-0.413040256335686	1.1083221744944	-1.52136243083009	0.668514170604518	2.15438240282637	0.756704207862196	2.2757369966509	0.706171025549685	0.173135716016033	NA	NA	0.402932705443228	0.0082798713527317	70.0522207441258
a2345	loss_cnaOV52, loss_cnaOV53	205	BMS-708163	g-secretase	8	24	2.32630161961136	0.940007258491471	5.372819128447	4.95839973610299	0.41441939234401	0.497920419125356	0.620845571575364	0.697158082658289	0.832300456912325	0.66750801055477	0.173476441133739	NA	NA	0.101840594434574	0.0754801984290232	70.0522207441258
a2346	NF1_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.38347716640622	5.10800512151402	0.275472044892199	0.469177725385267	0.595478622428999	0.471635040938392	0.587137943656626	0.462606102916893	0.173523771615126	NA	NA	0.0100230485713408	0.34305507265955	70.0522207441258
a2347	PTEN_mut	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.36086509031322	4.75496180316945	0.605903287143772	0.166759508948498	0.755344065530282	0.828868086757605	3.63339572636245	0.802155355147199	0.173571541359335	NA	NA	0.759191182952273	0.00290782444856785	70.0522207441258
a2348	gain_cnaOV50	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-3.10925708871752	-2.18639217947813	-0.922864909239387	1.31256160541243	1.62651718747395	0.5772122763332	0.703102167116497	0.567387124062695	0.173675513763476	NA	NA	0.115362412858348	0.264910066472313	70.0522207441258
a2349	loss_cnaOV38	276	CAY10603	HDAC6	8	23	2.99573227355399	NA	0.63701175342093	1.71012190637735	-1.07311015295642	1.37436347417244	1.83987145379011	0.617100771959885	0.780805204098267	0.583252786897599	0.173698679398635	NA	NA	0.605009378533252	0.101775232299802	70.0522207441258
a2350	ARID1A_mut	279	BIX02189	MAP2K5 (MEK5)	8	24	2.99573227355399	NA	4.76240784268883	4.32077474760685	0.441633095081983	0.712301829425462	0.718718325577085	0.615751414685953	0.620008368416239	0.614473124401523	0.173723014576535	NA	NA	0.513520144947376	0.155313884452015	70.0522207441258
a2351	loss_cnaOV41	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-1.24345577915403	-2.48661152371306	1.24315574455903	1.11330231822683	1.61845492352865	0.795630842949678	1.11663806336001	0.768112677397667	0.173865632573732	NA	NA	0.115372076926901	0.0686581455453339	70.0522207441258
a2352	loss_cnaOV59	152	CP466722	ATM	4	28	2.77258872223978	NA	3.19800548241852	2.56818971395533	0.629815768463197	0.588798140213729	0.811340966778452	0.795316348788021	1.06966331149514	0.776265213087875	0.173914536340769	NA	NA	0.545590022004141	0.118548865426254	70.0522207441258
a2353	TP53_mut	157	JNK-9L	JNK	12	7	1.63315443905142	NA	0.179502821181902	-0.393217886662019	0.572720707843922	0.998008333737314	0.940491331376887	0.585547413598467	0.573863652720427	0.608959050165251	0.174059572211396	NA	NA	0.170767038075487	0.232200598068832	70.0522207441258
a2354	loss_cnaOV38	262	VX-11e	ERK	8	24	1.63315443905142	NA	2.33645408253476	3.03355208888526	-0.697098006350491	0.751665961036751	1.16857369513435	0.642066406368259	0.927403983265391	0.596537479196249	0.174106550670114	NA	NA	0.378551479263467	0.0657787257301309	70.0522207441258
a2355	NF1_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	1.27754086219148	2.49099382659467	-1.21345296440319	1.52459257494864	1.51005288998195	0.802831760008405	0.795919502916423	0.803583088018652	0.174326060223507	NA	NA	0.23064994267523	0.212010707378613	70.0522207441258
a2356	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.24204425762616	5.72309206688235	0.518952190743811	0.52124460972924	0.548677046730614	0.949020387987365	0.995602028409233	0.945824495185421	0.174386900846392	NA	NA	0.101673922873071	0.21924668302743	70.0522207441258
a2357	gain_cnaOV4_(KRAS)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	7	26	-1.38629436111989	0.693147180559945	-1.56794346881828	-2.49487681838492	0.92693334956664	1.93842198079012	1.4826238712205	0.586247085347395	0.478189660844029	0.625197912673284	0.174445239726685	NA	NA	0.115401466930726	0.273457234956503	70.0522207441258
a2358	gain_cnaOV48_(SOX17)	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	2.7315889895221	4.00854587920444	-1.27695688968233	0.702751109838181	1.60115038723854	0.820700259496965	1.81708270795384	0.797524642194704	0.174469996517754	NA	NA	0.708201772990504	0.0556781811664015	70.0522207441258
a2359	loss_cnaOV84	1375	Temozolomide	DNA akylating agent	6	27	3.40119738166216	NA	6.30441201462035	5.86784697803429	0.436565036586064	0.748908830156649	0.674013136126306	0.635793591807307	0.582934823314538	0.647709982471698	0.174567926795561	NA	NA	0.906387992269606	0.230579164122536	70.0522207441258
a2360	loss_cnaOV40	203	BMS-345541	IKBKB	7	25	2.77258872223978	NA	3.8421916926188	3.11771067954463	0.724481013074168	1.30513599522846	0.912316994127707	0.722125730170429	0.55510001695061	0.794111057601054	0.174573146863607	NA	NA	0.0840829876486287	0.206994306351859	70.0522207441258
a2361	loss_cnaOV35	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.23411247132997	4.62964266176142	0.604469809568552	0.602504552396206	0.667280402183716	0.915877540357724	1.0032618129847	0.905870766757704	0.174651126772921	NA	NA	0.954802885169293	0.215003184630375	70.0522207441258
a2362	loss_cnaOV85	150	Bicalutamide	ANDR (androgen receptor)	6	13	0.0237165266173161	NA	3.26116305858832	2.84401319653845	0.417149862049874	0.619370393154708	0.55507788836236	0.725813138419201	0.673506300366019	0.751515905777812	0.174958365003975	NA	NA	0.842281779988387	0.19282308350199	70.0522207441258
a2363	gain_cnaOV50	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	4.05670428514929	3.11155588142496	0.945148403724334	0.659980382766017	1.24395045740689	0.788657028241839	1.43208560194344	0.759795856898168	0.17503774596331	NA	NA	0.59145058595955	0.0544169502831702	70.0522207441258
a2364	loss_cnaOV82	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.27541950848873	4.36633991057389	0.909079597914847	1.12037857070888	0.940831962359986	0.953059715299337	0.811403950130586	0.966250759205191	0.175059689491775	NA	NA	0.0274340687534894	0.292574142407511	70.0522207441258
a2365	loss_cnaOV54	1059	AZD8055	MTORC1/2	11	22	0.693147180559945	NA	0.76015219320878	0.0416100148837899	0.71854217832499	0.819014640238493	1.20248897996298	0.65705505551659	0.87732519423066	0.597545749107083	0.175084362024873	NA	NA	0.137187057782892	0.0532696487433796	70.0522207441258
a2366	SMAD4_mut	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.6149018409058	3.62808653913754	0.986815301768261	1.34556097506618	1.55682218291278	0.641769886657787	0.73338579228617	0.633865134116957	0.175137358718938	NA	NA	0.155063109774942	0.245967610880469	70.0522207441258
a2367	ARID1A_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	6	17	2.30258509299405	NA	3.54280380635523	3.96328065846873	-0.4204768521135	0.934963998986971	0.851859004726452	0.481996862929757	0.44972517933213	0.493599116497599	0.175273642917572	NA	NA	0.93754811000581	0.36055246085032	70.0522207441258
a2368	gain_cnaOV18_(CCNE1)	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	2.71850917973122	1.3614159802606	1.35709319947062	2.26970117563235	1.82966845545378	0.722505128069477	0.597917124086842	0.741715361286066	0.175304978662076	NA	NA	0.777057337324249	0.323347345113251	70.0522207441258
a2369	loss_cnaOV36	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	1.88801837209184	3.01056133366402	-1.12254296157218	0.692589019852581	1.24056606613377	0.926367622661777	1.62079231607096	0.904863507245999	0.175311197324801	NA	NA	0.219895817865857	0.0804814733208748	70.0522207441258
a2370	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	256	JW-7-24-1	LCK	7	25	2.32630161961136	NA	2.55438600366715	1.76713250295047	0.787253500716681	0.813798971181606	1.4076443533771	0.600690231057812	0.967380801149967	0.559270172773378	0.175351595485636	NA	NA	0.83489435470669	0.0759743256486852	70.0522207441258
a2371	PIK3CA_mut	205	BMS-708163	g-secretase	6	26	2.32630161961136	0.940007258491471	4.61182058042936	5.16589320044121	-0.55407262001185	0.747699183080031	0.541826091085014	0.953285011277136	0.741036813400588	1.022602324119	0.175404650984333	NA	NA	0.101935243661426	0.135196599125337	70.0522207441258
a2372	PTEN_mut	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	0.579161185906048	2.51932860132484	-1.94016741541879	0.400036858174516	1.76583638297621	1.15292170151961	4.84997163579459	1.09872434055796	0.175456670134161	NA	NA	0.102183871199138	4.10962614243584e-05	70.0522207441258
a2373	SMAD4_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.581223909635597	-0.458606730333233	1.03983063996883	0.886279319703937	1.41721062608487	0.756339161306276	1.17325386799749	0.733716372732418	0.175512539724071	NA	NA	0.886184989825473	0.0953076219223917	70.0522207441258
a2374	loss_cnaOV39	1013	Nilotinib	ABL	6	15	0.693147180559945	NA	3.78264264906355	3.03599097100643	0.746651678057118	0.83956766581045	1.02624297348686	0.761446974435261	0.889328768201621	0.727558382709531	0.175678084529113	NA	NA	0.549077256987504	0.111982773671013	70.0522207441258
a2375	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1018	ABT-888	PARP1, PARP2	8	23	1.6094379124341	NA	4.64420916771709	4.17971553508689	0.464493632630201	0.80992651537403	0.770629882589222	0.595278380792653	0.573500958189638	0.602745420498825	0.17580865818868	NA	NA	0.213113625595542	0.183172698431216	70.0522207441258
a2376	loss_cnaOV16, loss_cnaOV17	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.46786752197805	2.06120640679687	1.40666111518118	3.31554757337575	1.44719027944547	0.793667895262701	0.424262081617179	0.971994585066027	0.175906728331401	NA	NA	0.387178914459602	0.540814419228665	70.0522207441258
a2377	loss_cnaOV54	1199	Tamoxifen	ER	10	22	1.6094379124341	NA	4.27891428316692	3.84390486505173	0.435009418115191	0.523781703625989	0.814045666215417	0.588617781284778	0.830516635277154	0.534379625331826	0.175958096709736	NA	NA	0.514900730343947	0.0813047578469518	70.0522207441258
a2378	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	1.99689940432777	0.455269375475871	1.54163002885189	1.92507657607629	2.30367039468486	0.683085136802122	0.800814911993819	0.669205990756673	0.175992323097095	NA	NA	0.944427250902399	0.159888104423906	70.0522207441258
a2379	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.84914220010347	-2.22813924093561	-0.621002959167856	1.39738818607483	0.582882401699195	0.85340795231821	0.444402611497821	1.06540008303138	0.176006177021146	NA	NA	0.659520348810853	0.52355207751754	70.0522207441258
a2380	loss_cnaOV39	1230	IOX2	EGLN1	9	23	-2.30258509299405	NA	-0.467657026988709	0.094832525782545	-0.562489552771255	1.21463809779783	0.812276712320948	0.600546744726511	0.463092301971315	0.692485139902672	0.176087812070779	NA	NA	0.538630484594623	0.226500917141126	70.0522207441258
a2381	loss_cnaOV82	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	5.0793329551448	4.43076750433119	0.64856545081361	0.922707924189613	0.659014845392822	0.955002835876993	0.702893552565104	0.984143916252777	0.17611036954013	NA	NA	0.0744338180674609	0.346992274651919	70.0522207441258
a2382	PTEN_mut	308	XL-880	MET	3	29	1.63315443905142	NA	1.1273871423252	0.162654737782555	0.964732404542648	0.485563721207122	0.959177990025222	1.03169272651923	1.98682966294167	1.00579080689422	0.176116463135659	NA	NA	0.35610586613217	0.0453480443343297	70.0522207441258
a2383	loss_cnaOV42	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	1.10429495624876	0.167583263025687	0.936711693223075	0.977827010101845	1.11654622666023	0.848559965727855	0.95795236125203	0.838936777409501	0.17612771448707	NA	NA	0.137243927806307	0.149739373827967	70.0522207441258
a2384	PIK3R1_mut	262	VX-11e	ERK	5	27	1.63315443905142	NA	3.58787183955046	2.72435272576933	0.863519113781128	0.901693510119975	1.10733027530647	0.797949896014605	0.957663667409819	0.779820739157641	0.176159723347502	NA	NA	0.378695815278431	0.1036313250238	70.0522207441258
a2385	loss_cnaOV83	1033	Vismodegib	SMO	5	26	2.30258509299405	NA	5.4676574133784	4.80388292201166	0.663774491366743	0.759687196263781	0.840567265662181	0.799843780153365	0.873747108851188	0.789674447819277	0.176204512393941	NA	NA	0.143787930410055	0.128873204517349	70.0522207441258
a2386	loss_cnaOV16, loss_cnaOV17	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.63885763683024	1.86439313557005	0.774464501260191	1.19928919796828	0.914844977998989	0.810919587645634	0.645769596334407	0.846552716454925	0.176370633325231	NA	NA	0.457283971867746	0.381604568105649	70.0522207441258
a2387	loss_cnaOV55	260	NG-25	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.43647921821614	2.89312243759744	0.543356780618698	1.02525485510381	1.07578095730281	0.509778982705168	0.529972404338123	0.505081240683977	0.176375687795976	NA	NA	0.422788486027887	0.248239787026575	70.0522207441258
a2388	PIK3R1_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.0867370528484	4.51956316910325	-0.432826116254856	0.399224437115962	0.555231097518319	0.805925155410212	1.08416739060774	0.77954228102394	0.17648347783448	NA	NA	0.352683571975163	0.0747671040287661	70.0522207441258
a2389	BRCA1_mut	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	5.07960440508014	4.2014473059607	0.878157099119441	0.665548316062715	1.33664255370593	0.682284916961394	1.31944905865661	0.656987237675988	0.176495421319991	NA	NA	0.359350026847966	0.0720351191997722	70.0522207441258
a2390	loss_cnaOV42	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	3.46066672745178	1.83922240743034	1.62144432002145	3.35355971507252	1.69483480601285	0.841828421229924	0.483499462596085	0.956697557938373	0.176506081123439	NA	NA	0.123040081362248	0.407858113469095	70.0522207441258
a2391	loss_cnaOV1	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	4.25167817500372	3.48359045313278	0.768087721870936	0.787026528920376	0.949731373105848	0.817322244802886	0.975936253285616	0.808742075518792	0.176527921224594	NA	NA	0.721708025169091	0.225065885914267	70.0522207441258
a2392	gain_cnaOV18_(CCNE1)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	2.13038445258492	1.22278861459109	0.907595837993824	0.757961610809128	1.37725186486161	0.684120021146184	1.19741663040818	0.65899045857166	0.176789457474188	NA	NA	0.570754216022611	0.0938388758571432	70.10297411974
a2393	gain_cnaOV96	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.68702146202513	3.88879800525908	0.798223456766042	1.31797237402988	0.960683570514626	0.785954315980159	0.605645059406948	0.8308911292596	0.176854080855834	NA	NA	0.0963664524067452	0.254787174666737	70.10297411974
a2394	loss_cnaOV57_(ZNRF3)	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.53314814030366	4.81876483251779	0.714383307785871	0.68971649799262	0.846142771252271	0.859329082118703	1.03576369401782	0.844282232333677	0.176877468030984	NA	NA	0.143827751055368	0.126911064269346	70.10297411974
a2395	loss_cnaOV39	304	SB52334	ALK5	9	23	2.99573227355399	NA	3.90425901824055	4.54757235128767	-0.643313333047121	1.43293444860786	0.834497693488272	0.625363385782236	0.448948194156487	0.770898874936389	0.177011700239081	NA	NA	0.339650041970743	0.233842543195631	70.1268824599439
a2396	loss_cnaOV56	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	5.36424496001191	4.2022551537715	1.16198980624041	1.0455228973432	1.28916071488748	0.9114732044489	1.1113958471815	0.901353720154148	0.177128558056642	NA	NA	0.359392860916594	0.182786512878369	70.143890488343
a2397	loss_cnaOV42	290	KIN001-260	IKK	4	27	2.99573227355399	NA	4.30808445117469	4.93056671305142	-0.622482261876725	1.22243900418909	0.835688047709782	0.704498401028782	0.509213351131292	0.744873955757352	0.177433966555798	NA	NA	0.656973542144662	0.388981019088772	70.1919808797653
a2398	loss_cnaOV20	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.94546022898664	3.15225213674127	0.793208092245376	1.08109779901776	0.994928943976714	0.787816040784996	0.733706139228153	0.797250996714335	0.177450608777244	NA	NA	0.084208906113748	0.184086022203228	70.1919808797653
a2399	BRCA1_mut	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	2.25832398536674	1.47110703215726	0.787216953209475	0.770083107795224	1.05474175044807	0.762723613118804	1.02224934587035	0.746359905517207	0.177540123929339	NA	NA	0.270396777539526	0.208472254799457	70.1919808797653
a2400	loss_cnaOV39	1061	SB590885	BRAF	10	23	1.6094379124341	NA	4.31716848343826	3.75813605939446	0.559032424043802	1.20675266766248	1.29015613068773	0.441396622282245	0.463253522469246	0.433306024555186	0.177578264239903	NA	NA	0.563650314053301	0.246443745529391	70.1919808797653
a2401	loss_cnaOV43_(NF1)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-1.45769010979076	-2.24248401737748	0.78479390758672	0.950454862057714	1.3119133145837	0.617431356025105	0.825703501466296	0.59820561226315	0.177619884045134	NA	NA	0.598646141289703	0.154389420281858	70.1919808797653
a2402	PTEN_mut	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	3.33600230195596	2.20824238971525	1.1277599122407	0.514528389379351	1.45926973053546	0.79642137138076	2.19183224000732	0.77282485111706	0.17781202206605	NA	NA	0.816403175221856	0.0289341503331058	70.2173195389848
a2403	loss_cnaOV84	1038	NU-7441	PRKDC (DNAPK)	6	27	0.693147180559945	NA	3.11068436558836	2.4095690928477	0.701115272740665	0.801079418965102	1.04044969507448	0.697139800924089	0.875213188782732	0.673857925145025	0.177832011521407	NA	NA	0.383594861294682	0.100028777664978	70.2173195389848
a2404	gain_cnaOV18_(CCNE1)	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	0.943690886127583	-0.101285840350645	1.04497672647823	0.971836818262831	1.32643586408511	0.822124745838388	1.07525945389282	0.787807955719735	0.177979188781043	NA	NA	0.863695783406427	0.12631526107109	70.22037178122
a2405	gain_cnaOV94	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	3.0723065873935	2.38339417246315	0.688912414930343	0.160453559872657	0.781496703116615	0.935833548975508	4.29353150828871	0.881529521727929	0.178035907720458	NA	NA	0.737696038534923	0.00563076869742193	70.22037178122
a2406	loss_cnaOV33_(ZFHX3)	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	2.27477589818811	3.11729685266774	-0.842520954479622	1.45244762206878	0.99784052961986	0.800740301422107	0.580069767527715	0.844344290966605	0.178061763763255	NA	NA	0.422902494129834	0.334137300830976	70.22037178122
a2407	loss_cnaOV20	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.35371653412117	2.76366750471593	0.590049029405238	1.44747667228389	0.984970866203751	0.557501512354462	0.407639750403876	0.599052266062843	0.178177190294789	NA	NA	0.294738107654599	0.424048525431733	70.2366990353277
a2408	KRAS_mut	312	AV-951	VEGFR	7	25	-2.05572501506252	NA	0.267360359614332	0.744143417868677	-0.476783058254345	0.714076941243063	0.552129652795423	0.810720842180002	0.667691435917763	0.863534598876189	0.178321302607852	NA	NA	0.0129056055811099	0.140131906674463	70.2643158470888
a2409	BRCA1_mut	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	3.34846849587828	2.34563654466089	1.00283195121739	1.46922384929499	1.43675363878226	0.696923550855627	0.682558993102787	0.697984625998484	0.178413682655564	NA	NA	0.228520546357376	0.358975306700749	70.2710273779646
a2410	loss_cnaOV55	293	MP470	PDGFR	7	25	2.99573227355399	NA	4.7783287122483	3.84509865182443	0.933230060423873	0.917331155318842	1.88624250308943	0.537491822717816	1.01733169642484	0.494756140260523	0.178556310261479	NA	NA	0.613321580168449	0.0826991739920739	70.2710273779646
a2411	loss_cnaOV43_(NF1)	173	FH535	unknown 	3	15	3.46573590279973	NA	3.26873572323106	2.34244452078829	0.926291202442765	1.71533005300093	1.36542490656192	0.65512902187934	0.540007563455349	0.678390439482408	0.178560517874576	NA	NA	0.104643145883453	0.453791358589494	70.2710273779646
a2412	PTEN_mut	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.44895535738203	3.97712120352407	-0.528165846142039	1.50721097038505	0.624870806472746	0.735354392516661	0.350425956631079	0.845240073101535	0.17874567445346	NA	NA	0.954653994157472	0.606673019692939	70.3147300958031
a2413	loss_cnaOV38	272	AR-42	HDAC	8	22	1.63315443905142	NA	-0.535148128912711	0.597005376319561	-1.13215350523227	1.4134027026458	1.89396346496953	0.633909108526301	0.801012693065431	0.597769453409432	0.179148042751691	NA	NA	0.474218293655182	0.09627750795426	70.4438076305111
a2414	loss_cnaOV44	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.59403030393544	3.71894886593024	0.8750814380052	1.33747593703789	0.977763153245092	0.870074561014967	0.654278266824928	0.894983038684673	0.179311264669129	NA	NA	0.710288248773409	0.374811763177968	70.4653587748988
a2415	loss_cnaOV87, loss_cnaOV88	333	T0901317	LXR	3	29	2.32630161961136	NA	5.68378259297652	4.65710028504018	1.02668230793634	0.939135214929753	1.09539621315917	0.945659397957467	1.09322096713532	0.937270273169326	0.179365259217305	NA	NA	0.00420555382276086	0.188342563027277	70.4653587748988
a2416	loss_cnaOV41	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	3.30230316862892	1.80849549906341	1.49380766956551	2.92577633385281	1.71915434824611	0.776301862897615	0.510567965254674	0.86892004262997	0.179425646946905	NA	NA	0.123194123434711	0.323708232349541	70.4653587748988
a2417	gain_cnaOV72_(ASXL1)	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.03311487337722	2.2623277124492	0.77078716092802	1.56590371327237	1.2396801321859	0.599167380191883	0.492231517426608	0.621762937806312	0.179598912356539	NA	NA	0.10188759646821	0.344974080195681	70.4721824348291
a2418	loss_cnaOV83	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	2.97482005218086	3.76715308567769	-0.792333033496829	1.06134262416023	0.817455940370373	0.922962266488897	0.746538408484019	0.969266959070404	0.17964920252128	NA	NA	0.0511963583316042	0.236114330834449	70.4721824348291
a2419	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-3.34912237140256	-4.33794881734072	0.988826445938162	2.566109129835	0.965644846426805	0.761508256073934	0.385340761404697	1.02400634104468	0.179665840325536	NA	NA	0.206504909654336	0.440664495828468	70.4721824348291
a2420	loss_cnaOV35	255	CP724714	ERBB2	5	27	2.32630161961136	NA	4.92286015407571	4.32103425489537	0.601825899180336	0.784775847211768	0.951844306018528	0.646220073585221	0.766876174029266	0.632273466758146	0.179805663044487	NA	NA	0.781146547389743	0.176200440841246	70.4826110930129
a2421	TP53_mut	306	TG101348	JAK2	22	10	2.32630161961136	NA	3.0459133964289	2.33597810623662	0.709935290192281	1.45399624004469	1.13763687721372	0.519414643820233	0.488264873484445	0.624043844228259	0.179971773248471	NA	NA	0.618733993433983	0.149066328237776	70.4826110930129
a2422	NF1_mut	281	CH5424802	ALK	4	28	1.63315443905142	NA	4.38573608758998	3.86215845085658	0.523577636733401	0.525866600436384	0.731454519767265	0.733747817906986	0.995647254073402	0.715803406204931	0.180150277395956	NA	NA	0.954663238313246	0.140121307472109	70.4826110930129
a2423	loss_cnaOV33_(ZFHX3)	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.89979799645304	4.09663578072417	0.803162215728874	1.2241193731473	0.906096934703049	0.851945229466971	0.65611429191247	0.886397674429934	0.18016827620971	NA	NA	0.0430614831348834	0.28424006701599	70.4826110930129
a2424	loss_cnaOV36	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.93441348301728	3.99605068523012	0.938362797787165	1.51326384349842	1.0573099791913	0.85802033145955	0.620091996394908	0.887500180888192	0.180404562082064	NA	NA	0.815129578044878	0.395733626045278	70.4826110930129
a2425	PIK3CA_mut	272	AR-42	HDAC	6	24	1.63315443905142	NA	-0.212670432992407	0.422039826903462	-0.634710259895869	0.861120719230575	1.99119112274101	0.344765410585329	0.737074658316192	0.318759084774417	0.180469193721076	NA	NA	0.474308462770486	0.25165458489811	70.4826110930129
a2426	SMARCA4_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	0.243814198043746	1.53386897801133	-1.29005477996758	0.950975686235654	1.45487809895222	0.904758781576827	1.35655916196358	0.886709876859551	0.180556857859463	NA	NA	0.465009079830926	0.12311883847433	70.4826110930129
a2427	loss_cnaOV57_(ZNRF3)	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.80433564948215	1.81577400005369	0.988561649428464	0.894925837296153	1.34845598988545	0.754519627641026	1.10462968910945	0.73310635040632	0.180613835430577	NA	NA	0.835019843092579	0.110730645847841	70.4826110930129
a2428	loss_cnaOV39	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	3.90299441097997	3.11117960238189	0.791814808598076	0.964457470539684	0.906103268408484	0.860512387057815	0.820995049325501	0.873868173976296	0.180766973427337	NA	NA	0.170900890036759	0.155283244268354	70.4826110930129
a2429	gain_cnaOV19	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.93366318401108	3.99612830236869	0.937534881642387	0.790594523746016	1.1121953988998	0.857212865080139	1.18586058147751	0.842958784553337	0.180810115359371	NA	NA	0.815140186076621	0.161403546851684	70.4826110930129
a2430	gain_cnaOV18_(CCNE1)	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.944834588843551	0.2989400240463	0.645894564797251	1.02838956345172	0.874042861392662	0.724706242767705	0.628064099201229	0.738973559909992	0.181104165867247	NA	NA	0.907290714734921	0.303916524993039	70.4826110930129
a2431	SMAD4_mut	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	5.12215077069218	3.70696647486863	1.41518429582356	0.893213340996058	1.48276712911122	0.984765439951583	1.58437433798898	0.95442114141809	0.181230158786427	NA	NA	0.0606330208558223	0.0834534847824332	70.4826110930129
a2432	ARID1A_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	8	24	2.32630161961136	NA	0.134750059737983	1.6749404705466	-1.54019041080862	1.52400883430007	2.41989438205285	0.686637628450711	1.01061777080576	0.636470096476705	0.1815142702415	NA	NA	0.351648304061524	0.0482644412825093	70.4826110930129
a2433	loss_cnaOV58	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	4.98371147904811	3.69467579573882	1.28903568330929	1.71991950381759	1.64858523555944	0.777179763077143	0.749474426243848	0.781904177900672	0.181518746319906	NA	NA	0.137351609429455	0.177642989587652	70.4826110930129
a2434	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.86592150630386	1.56129996492417	1.30462154137969	0.729734407586856	1.48180051465257	0.903539185549939	1.78780324432545	0.88042994214075	0.181627784425695	NA	NA	0.314567429740258	0.0602499018226655	70.4826110930129
a2435	loss_cnaOV36	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	2.24740281919967	1.0599209885679	1.18748183063177	1.36062236833688	1.46990982280043	0.811617430079711	0.872749014175955	0.807860327356281	0.181649691819191	NA	NA	0.808608564753541	0.265171718061544	70.4826110930129
a2436	loss_cnaOV70	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	3.97232627693535	2.70447991840221	1.26784635853314	0.860005294731352	1.56285293602319	0.830122765374501	1.47423087543802	0.811238427691911	0.181662640856632	NA	NA	0.968051191791947	0.100600668541471	70.4826110930129
a2437	NF1_mut	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	3.87411778019453	2.69701461174724	1.17710316844729	1.93122721585878	1.81226406592448	0.645161447267272	0.609510449511689	0.649520779327944	0.181668244022071	NA	NA	0.33447182525105	0.317809248273983	70.4826110930129
a2438	gain_cnaOV49	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	2.32386342729338	3.66963563544187	-1.34577220814849	1.7070164688463	1.67111986882222	0.804108480660109	0.788376815753886	0.805311595688806	0.181671217236736	NA	NA	0.691060060805655	0.30307905562916	70.4826110930129
a2439	loss_cnaOV1	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	1.67219451801252	2.46815462780726	-0.79596010979474	0.371496728789196	0.94675497155592	0.865486324855134	2.14257636235177	0.840724510257009	0.181720023375429	NA	NA	0.728381829278282	0.031919029311742	70.4826110930129
a2440	SMAD4_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	1.28136423041226	0.459682735687187	0.821681494725071	1.24578281111922	1.18233845436309	0.691035290966554	0.659570422220602	0.694963013080464	0.181747220234021	NA	NA	0.419089771299217	0.28556199534004	70.4826110930129
a2441	loss_cnaOV44	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	5.05187897268773	4.33007264235374	0.721806330333993	0.740665766061062	0.74691473675084	0.966939580309805	0.974537184528772	0.966383838500669	0.181751124772588	NA	NA	0.0382683485771197	0.226747637816861	70.4826110930129
a2442	loss_cnaOV40	255	CP724714	ERBB2	7	25	2.32630161961136	NA	4.8196739835475	4.30178031070885	0.517893672838658	1.04715492639969	0.90142715988978	0.555443542446751	0.494572159077997	0.574526368721775	0.182010354736095	NA	NA	0.781214139277776	0.265366904146105	70.4826110930129
a2443	gain_cnaOV96	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	1.00961489010045	-0.330724395468089	1.34033928556854	1.62867581470529	1.54535182611619	0.862410007982565	0.822962601560507	0.867336009132053	0.182052611046225	NA	NA	0.0923955266178017	0.19979737331912	70.4826110930129
a2444	loss_cnaOV56	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.97664534916352	4.20566040945202	0.770984939711504	1.49400892136206	0.810525791295259	0.883242523959193	0.516051094934968	0.951215800893187	0.182080834982463	NA	NA	0.511185597007564	0.46676255090193	70.4826110930129
a2445	gain_cnaOV19	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.76694845425074	2.24026998471945	1.5266784695313	1.24777068572002	1.52965906900456	1.01518012390131	1.22352487280172	0.998051461574894	0.182197667834454	NA	NA	0.210514588320569	0.151555396054153	70.4826110930129
a2446	gain_cnaOV72_(ASXL1)	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	4.84311490390887	3.74302192483908	1.10009297906979	1.07047560776779	1.60494006622282	0.706013594678933	1.02766748825203	0.685441782046622	0.18221950094434	NA	NA	0.708528096146454	0.132226773814408	70.4826110930129
a2447	KRAS_mut	1052	RO-3306	CDK1	7	26	1.6094379124341	NA	3.06216756200411	3.59476437903939	-0.532596817035279	1.25573003828853	0.769037642103282	0.602218109164963	0.424133213983771	0.692549737329699	0.182431890138051	NA	NA	0.789339168933497	0.319150101705563	70.4826110930129
a2448	loss_cnaOV39	224	AS605240	PI3Kgamma	9	23	2.99573227355399	2.32630161961136	3.93956039488469	3.15422568413712	0.785334710747573	1.29437891795601	1.75212300658314	0.478110971608922	0.606727056392202	0.448218936568315	0.182508016647884	NA	NA	0.621219122293921	0.180179569243988	70.4826110930129
a2449	ARID1A_mut	261	TL-1-85	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	3.92506307633567	3.43244387729902	0.492619199036657	0.939645663854944	0.943211513575658	0.522739063818513	0.52426059948562	0.522278610837952	0.182663652895585	NA	NA	0.721945019780501	0.223583259419933	70.4826110930129
a2450	loss_cnaOV33_(ZFHX3)	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	5.16205075533652	4.35006831824153	0.811982437094995	0.942465909852586	0.95393192025348	0.852214165238774	0.861550989384857	0.851195373438426	0.182680133890037	NA	NA	0.027592496059509	0.18402987296091	70.4826110930129
a2451	loss_cnaOV54	229	LY317615	PRKCB (PKCbeta)	10	22	2.99573227355399	2.32630161961136	2.29428689011378	2.95571507016778	-0.661428180054008	1.71899408753739	1.63981273772263	0.397501777923024	0.384776297283	0.403355922806527	0.182750895884583	NA	NA	0.309520733965571	0.320673427199433	70.4826110930129
a2452	BRCA1_mut	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.3715188268533	3.60164054587161	0.769878280981687	0.825053812994373	1.24062773608951	0.638012443914411	0.933124929375895	0.620555432210764	0.182857511857931	NA	NA	0.187812706989427	0.1629051409013	70.4826110930129
a2453	loss_cnaOV52, loss_cnaOV53	1031	Elesclomol	HSP70	8	23	-1.6094379124341	NA	-3.47257254778147	-4.26401654037249	0.791443992591018	2.15382498604104	1.21283784050617	0.529318549134852	0.367459750778441	0.652555491062775	0.182918046530749	NA	NA	0.860589395610538	0.350903332862227	70.4826110930129
a2454	loss_cnaOV20	255	CP724714	ERBB2	5	27	2.32630161961136	NA	4.91909290260531	4.32173189405656	0.59736100854875	0.814613715681991	0.948437902897408	0.641147590776564	0.733305856566191	0.629836710156623	0.183047717687905	NA	NA	0.781245609087431	0.191444804791834	70.4826110930129
a2455	loss_cnaOV16, loss_cnaOV17	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.25056998724719	-3.68261621225689	1.4320462250097	2.01985514818391	1.65900848299943	0.839698788707329	0.708984615207323	0.863194034077877	0.183063035380058	NA	NA	0.667453930505046	0.344683795417647	70.4826110930129
a2456	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.47421326141284	-4.77439945591243	1.30018619449958	2.50128504133213	1.25408615130327	0.944312052050585	0.519807288259771	1.03675986944629	0.183078929047322	NA	NA	0.125966569137798	0.463834416822729	70.4826110930129
a2457	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	6.2139020103794	5.67605080488044	0.537851205498963	0.863290491419701	0.562634699723668	0.915514755845906	0.623024591194622	0.955951002956489	0.183087549964099	NA	NA	0.18176597216213	0.393763131355989	70.4826110930129
a2458	loss_cnaOV41	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.58483640231355	1.51671412926462	1.06812227304893	0.97668805542275	1.50056615598218	0.740847942535877	1.09361660267936	0.71181285063024	0.183137953087365	NA	NA	0.314669831331606	0.0755774273958948	70.4826110930129
a2459	loss_cnaOV85	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	7	26	0.693147180559945	NA	3.22759336614168	2.68217046775271	0.545422898388967	1.0373129415858	0.918079881446777	0.578799124719399	0.525803618679572	0.594090894933292	0.183282112740939	NA	NA	0.965377358085178	0.238955197005101	70.4826110930129
a2460	loss_cnaOV83	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	5.25976942504058	4.78604433921962	0.473725085820954	0.480458468653545	0.616058891306699	0.789867190218171	0.985985504946013	0.76896071545393	0.183304694751774	NA	NA	0.0445622956859959	0.0966628811081569	70.4826110930129
a2461	loss_cnaOV52, loss_cnaOV53	229	LY317615	PRKCB (PKCbeta)	8	24	2.99573227355399	2.32630161961136	2.19370049569264	2.93412485330366	-0.740424357611027	1.90913653779885	1.57794455334319	0.445732824105089	0.38783206069939	0.469233444256512	0.183319800190708	NA	NA	0.309559127602215	0.344670035814741	70.4826110930129
a2462	SMAD4_mut	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.22463385816669	4.63141990172954	0.593213956437149	0.614364956763099	0.667539713751221	0.896763110115707	0.96557258012015	0.8886571753216	0.183371088494968	NA	NA	0.954908179903948	0.228486340543596	70.4826110930129
a2463	loss_cnaOV84	326	GSK690693	AKT	6	26	2.32630161961136	NA	4.99667982624158	3.95698914621307	1.0396906800285	0.869190267747871	1.49369402104127	0.737910729066496	1.19616005678758	0.696053318405682	0.183421834358394	NA	NA	0.0860211644868137	0.0417623831362606	70.4826110930129
a2464	loss_cnaOV36	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.58371260864294	2.06847210919005	0.515240499452899	0.637891386254514	0.53530308447031	0.949739088315288	0.80772449754843	0.962521073389175	0.183423543297933	NA	NA	0.0378971158188343	0.294296867770844	70.4826110930129
a2465	PIK3R1_mut	1239	YK 4-279	RNA helicase A	5	19	2.30258509299405	NA	0.918074777885791	1.74093924957757	-0.822864471691777	0.572471621835601	1.08195536195397	0.815808787596865	1.43738910420276	0.760534584537495	0.183671188248285	NA	NA	0.270968713912175	0.0387244658653857	70.4826110930129
a2466	gain_cnaOV95_(MECOM)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	5.66617638146485	4.80517253598024	0.861003845484603	0.773089506238102	1.22244139874855	0.760025514981316	1.11371818985656	0.704331386654639	0.183691575062299	NA	NA	0.791745261402034	0.0964546610724677	70.4826110930129
a2467	gain_cnaOV48_(SOX17)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	-1.07580617491222	-0.0594171640178549	-1.01638901089437	1.18262649157556	1.61831012295628	0.638397085743108	0.859433657316667	0.628055770322722	0.183866372616021	NA	NA	0.0924782580743407	0.271076133594991	70.4826110930129
a2468	loss_cnaOV43_(NF1)	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.46535555168246	3.5573883349742	0.907967216708264	0.974678667666221	1.21601275235117	0.764519159199297	0.931555441633198	0.74667573588575	0.183870286751476	NA	NA	0.187872167242147	0.111469112181108	70.4826110930129
a2469	loss_cnaOV54	1091	BMS-536924	IGF1R	10	22	1.38629436111989	NA	2.04919859760424	2.55004917201844	-0.500850574414202	0.942155864712766	0.909804481546301	0.544622184713517	0.531600548457972	0.550503525288156	0.184018828444372	NA	NA	0.728466899386425	0.176981674235671	70.4826110930129
a2470	loss_cnaOV43_(NF1)	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.5609246057373	3.78334245507946	0.777582150657833	0.804904748835128	1.07551829794569	0.744420182301006	0.966054867713432	0.722983655548275	0.18419441910427	NA	NA	0.305118894864767	0.10290815492932	70.4826110930129
a2471	gain_cnaOV26	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.79038225137207	2.68525450024249	1.10512775112958	1.37064039531936	1.1797061734046	0.926043922169827	0.806285700394878	0.936782205640423	0.184198527859498	NA	NA	0.0872205383579343	0.29485472925849	70.4826110930129
a2472	loss_cnaOV59	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	2.9798377627492	3.76603803888473	-0.786200276135526	1.05783411426689	0.819396104612997	0.914835720871796	0.743216980367843	0.959487446559013	0.184234712407253	NA	NA	0.0514089807337502	0.237911691630263	70.4826110930129
a2473	loss_cnaOV85	254	AC220	FLT3	7	25	0.0237165266173161	NA	2.22462651437684	2.59095349438511	-0.366326980008269	0.602474228824764	0.618126535211092	0.595626563722043	0.60803759311474	0.592640760654559	0.184252052976024	NA	NA	0.854615043421552	0.188255175278005	70.4826110930129
a2474	loss_cnaOV57_(ZNRF3)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.56758239270829	5.08170437489944	0.485878017808849	0.727365042109676	0.547268933888223	0.855637942592651	0.66799748362884	0.887823129949648	0.184419860761547	NA	NA	0.0101293071617845	0.277170178750365	70.4826110930129
a2475	gain_cnaOV49	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	0.833933293491488	2.16686532542697	-1.33293203193548	2.03341149117512	1.95847499699718	0.678834468824226	0.655515146698208	0.680596910340542	0.184474570409181	NA	NA	0.123454003252195	0.374909769438296	70.4826110930129
a2476	gain_cnaOV94	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	7	26	-2.30258509299405	NA	0.274750007378934	-0.496074984337458	0.770824991716392	0.696796958029229	1.49939627345246	0.558183747853729	1.10624046622784	0.514090241095182	0.184484961813103	NA	NA	0.886326775436072	0.0636627651799316	70.4826110930129
a2477	loss_cnaOV56	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.33968205163231	4.02906036565836	1.31062168597395	0.481584802688454	1.46007881593743	0.925554036779273	2.72147642254777	0.897637628645733	0.184548853166038	NA	NA	0.0860686123513722	0.0114722949032832	70.4826110930129
a2478	loss_cnaOV55	1052	RO-3306	CDK1	8	25	1.6094379124341	NA	3.86452578033841	3.35931362185382	0.505212158484582	0.874022014659706	0.887804829691642	0.571047447920902	0.578031388238295	0.569057682035876	0.184589089273439	NA	NA	0.789399790335691	0.181749793096717	70.4826110930129
a2479	gain_cnaOV95_(MECOM)	344	THZ-2-49	CDK9	9	23	2.99573227355399	NA	3.48217928978185	2.23703956208354	1.24513972769831	1.92119773034301	2.39915949523685	0.545751377662048	0.648105974743163	0.51898997551865	0.184614342791702	NA	NA	0.374443132769809	0.142599653155005	70.4826110930129
a2480	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	3.34862896112826	2.27132298063553	1.07730598049273	1.69232769755884	1.3657710274875	0.762059461024542	0.636582372342384	0.788789598557063	0.184654235785442	NA	NA	0.228926673021881	0.236381184772273	70.4826110930129
a2481	loss_cnaOV81_(RB1)	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	0.058969835667957	-1.2191879408132	1.27815777648115	2.12330919639238	1.91975257763787	0.658481345301886	0.601964979312863	0.665792973203789	0.184675672553134	NA	NA	0.432473235782879	0.322336783123427	70.4826110930129
a2482	KRAS_mut	1170	CCT018159	HSP90	7	26	2.30258509299405	NA	3.06188332213115	3.86540261087584	-0.803519288744691	1.06012876119417	1.21520300549995	0.677063398354241	0.757944995133966	0.661222269125406	0.184819590842145	NA	NA	0.187927562956085	0.113590715180106	70.4826110930129
a2483	gain_cnaOV4_(KRAS)	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	3.09333001030024	2.25662220842796	0.836707801872279	1.30842093382121	1.45416588711067	0.586665673797316	0.639479069957016	0.57538676246543	0.184823913171697	NA	NA	0.228937494817077	0.173843108626006	70.4826110930129
a2484	loss_cnaOV82	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.35713599419168	2.39932570590317	-1.04218971171149	1.35441123856807	1.21664374710759	0.849628394210508	0.769478044802205	0.856610420420242	0.18493425101848	NA	NA	0.840577264712834	0.31231863194345	70.4826110930129
a2485	loss_cnaOV59	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	1.03505444043344	-0.0177749146636063	1.05282935509704	2.05451991761256	1.53403168840726	0.659763643475516	0.512445436070766	0.686315258709004	0.18529213862735	NA	NA	0.450585146872538	0.387493447194642	70.4826110930129
a2486	loss_cnaOV81_(RB1)	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	3.06597445927328	1.57965847948701	1.48631597978627	1.74182484918406	1.53180483032791	0.960646110801827	0.853309665712096	0.970303755647576	0.185378823066408	NA	NA	0.0366445930983498	0.273965777476997	70.4826110930129
a2487	loss_cnaOV57_(ZNRF3)	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.44314962291604	4.65452212237101	0.788627500545021	0.324474641149951	1.27090891465308	0.652894100361598	2.43047499105043	0.620522439847937	0.185425301695664	NA	NA	0.413238998149968	0.0141243743752042	70.4826110930129
a2488	loss_cnaOV82	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	2.85434623057411	3.61575471843726	-0.761408487863146	0.554261426533865	0.90118676192621	0.862969112016653	1.37373530145278	0.844895331391354	0.185505776482725	NA	NA	0.655513078413169	0.119175300811297	70.4826110930129
a2489	loss_cnaOV59	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.96703906370316	4.31590794996871	0.651131113734449	0.609909524598556	0.75901498730582	0.874030237217014	1.06758640006979	0.85786331577679	0.185558740298453	NA	NA	0.0383683424016103	0.118405646768731	70.4826110930129
a2490	loss_cnaOV70	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.274210321664067	-1.19737979189965	1.47159011356372	2.70337423380649	1.87317770557534	0.758703764918128	0.544353088507337	0.785611588897128	0.18557232627241	NA	NA	0.432530459869728	0.446778365899995	70.4826110930129
a2491	PTEN_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-3.79464740082626	-2.09185558470451	-1.70279181612176	1.50426439816592	1.52663553452221	1.11696204974361	1.13197641199107	1.11538856368536	0.185656652559674	NA	NA	0.115949422776647	0.103205818602389	70.4826110930129
a2492	loss_cnaOV52, loss_cnaOV53	1170	CCT018159	HSP90	9	24	2.30258509299405	NA	4.25294376864131	3.48571488416325	0.76722888447806	1.14253955843948	1.196479007082	0.648657717302135	0.671511877913414	0.64123890175825	0.185704148724983	NA	NA	0.187978888971153	0.110509284785154	70.4826110930129
a2493	loss_cnaOV52, loss_cnaOV53	1006	Cytarabine	DNA synthesis	8	23	0.693147180559945	NA	0.417913242117473	-0.295386705479844	0.713299947597317	1.16724751366953	1.24762208340177	0.580530906009123	0.611095709559392	0.571727574469049	0.185727834482139	NA	NA	0.761366246443846	0.167419490269327	70.4826110930129
a2494	TP53_mut	262	VX-11e	ERK	22	10	1.63315443905142	NA	2.6877694099807	3.23659557739488	-0.548826167414182	0.981093608399508	1.3331004364259	0.49956738205125	0.559402449180666	0.411691536824944	0.185737193240017	NA	NA	0.379344243775757	0.263537768461769	70.4826110930129
a2495	gain_cnaOV26	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.17613564589943	2.66843933748341	0.507696308416016	0.438792598495521	0.560706193959725	0.917388389354116	1.1570302465373	0.905458712397395	0.185799586174754	NA	NA	0.126580099260064	0.169981402057426	70.4826110930129
a2496	gain_cnaOV72_(ASXL1)	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-1.26353976811634	-2.14281249430218	0.879272726185841	1.24682892008764	1.57477894397654	0.569445238114428	0.705207195646405	0.558346763238753	0.185847378641585	NA	NA	0.0335396742435109	0.265573663707587	70.4826110930129
a2497	loss_cnaOV40	1059	AZD8055	MTORC1/2	8	25	0.693147180559945	NA	0.846191054488055	0.100302640673421	0.745888413814634	0.965943628873443	1.13571747725973	0.678280850608089	0.77218627621629	0.656755248333698	0.185962299810911	NA	NA	0.137762059932555	0.0907789471162453	70.4826110930129
a2498	loss_cnaOV44	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	4.24638118184509	2.88192140024551	1.36445978159958	0.755910378238926	1.62678540189913	0.861566320741627	1.80505496534974	0.838746020222883	0.186216801230794	NA	NA	0.655729158409438	0.0576601712218936	70.4826110930129
a2499	gain_cnaOV26	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	4.82775232802391	5.92527755903308	-1.09752523100917	1.67395473286305	1.21895261933405	0.874918693497048	0.655648094576618	0.900383832481349	0.186220116833987	NA	NA	0.561578561281962	0.373989334286052	70.4826110930129
a2500	PIK3R1_mut	293	MP470	PDGFR	5	27	2.99573227355399	NA	5.08905824318724	3.85668429871899	1.23237394446825	0.710906024286504	1.82686064140484	0.716325132968015	1.73352581405555	0.674585634249897	0.186319093244384	NA	NA	0.613712470422187	0.0192971480003629	70.4826110930129
a2501	NF1_mut	152	CP466722	ATM	4	28	2.77258872223978	NA	3.118247582803	2.57958369961469	0.538663883188311	0.754741144551538	0.804554892656393	0.673571363514551	0.713706794808942	0.669517876412147	0.18633222574166	NA	NA	0.546307128509106	0.255430142023779	70.4826110930129
a2502	loss_cnaOV16, loss_cnaOV17	1010	Gefitinib	EGFR	6	24	-0.693147180559945	NA	1.54298025566622	0.771037442546456	0.771942813119762	0.809091195627755	1.31542701037996	0.622401887032359	0.954086285070534	0.586838195527691	0.186444161209454	NA	NA	0.956349473146108	0.0936490799749589	70.4826110930129
a2503	loss_cnaOV58	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	5.08693130976982	4.3339059030837	0.753025406686125	1.04518416284657	0.93603264032961	0.791566750848157	0.720471504883173	0.804486269219157	0.18644895031694	NA	NA	0.0276682760898307	0.190273052931046	70.4826110930129
a2504	loss_cnaOV82	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.97006656510245	4.20634097332041	0.763725591782045	1.50080503948137	0.810296264219737	0.874347098777619	0.508877283651688	0.942526364128635	0.186620240677389	NA	NA	0.511453636695332	0.472140773436847	70.4826110930129
a2505	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	2.17963722414847	1.44748353674044	0.732153687408029	0.982465982939673	1.03567549879756	0.711808940664957	0.745220394519232	0.706933482792701	0.186640332259334	NA	NA	0.271237859638681	0.242198628051665	70.4826110930129
a2506	RB1_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	-0.391224244514254	0.66823441138378	-1.05945865589803	1.0327410665158	1.18914119900839	0.898591660749724	1.02587055966736	0.890944369584961	0.186775272054667	NA	NA	0.419427319083573	0.208560207763508	70.4826110930129
a2507	loss_cnaOV33_(ZFHX3)	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	1.83465013718667	2.87964285343151	-1.04499271624484	1.2343232606519	1.69616339370249	0.631115651286981	0.846611863810239	0.616092011020097	0.186939048454174	NA	NA	0.309800191407518	0.19565147449644	70.4826110930129
a2508	loss_cnaOV44	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.85816884292184	0.821787912086915	1.03638093083493	0.206846220659849	1.28520949906859	0.835998671602869	5.01039336144901	0.806390655831605	0.187055252177284	NA	NA	0.95635344896747	0.000976617290935132	70.4826110930129
a2509	loss_cnaOV59	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.42053277475863	0.199549615703586	1.22098315905505	1.55542605928699	1.64497557401437	0.746349978989567	0.784983093066311	0.74225002385621	0.187081508898117	NA	NA	0.833142999721375	0.218516647237671	70.4826110930129
a2510	loss_cnaOV43_(NF1)	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.42775525722275	3.89689902135902	0.530856235863723	0.882322244153191	0.717456292631785	0.715864932234502	0.601657998969767	0.739914391044544	0.187133081397055	NA	NA	0.515569146909619	0.259733790617056	70.4826110930129
a2511	loss_cnaOV41	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	1.9629195447393	2.89459269337528	-0.931673148635974	1.05854757138493	1.73123858960677	0.562130308961841	0.880142918297983	0.538154102056835	0.187142242895721	NA	NA	0.309813564594836	0.143476727002126	70.4826110930129
a2512	loss_cnaOV52, loss_cnaOV53	265	Tubastatin A	HDAC6	8	23	2.99573227355399	NA	5.17109641920659	4.61199671487082	0.559099704335772	1.12253844454483	1.23953799189246	0.461177447006912	0.498067310792617	0.451054915615914	0.187170757663872	NA	NA	0.413355149745288	0.258295619477674	70.4826110930129
a2513	loss_cnaOV84	1495	AZD-2281	PARP1, PARP2	6	27	2.30258509299405	NA	4.09099554482081	3.4435120854602	0.647483459360608	1.53910489942252	0.696123668252735	0.729168209696771	0.42068832319587	0.930127057719192	0.187173853065043	NA	NA	0.134027846095861	0.356075870804329	70.4826110930129
a2514	PIK3R1_mut	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	3.99054062986894	4.57886860164376	-0.588327971774826	0.598720419581843	0.68156667119575	0.87620327890071	0.982642235896555	0.863199444219676	0.187518095602749	NA	NA	0.0748683171058078	0.0948744531140265	70.4826110930129
a2515	loss_cnaOV44	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.96003569493363	2.29967711566502	0.660358579268611	0.946482663072031	0.848146252605882	0.7723005017088	0.697697490966462	0.778590458001431	0.187627404229685	NA	NA	0.599233267887295	0.350076994814712	70.4826110930129
a2516	gain_cnaOV49	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.19469276714342	1.65789989897212	-0.463207131828703	0.294045878203661	0.694347667869224	0.686144969330307	1.57528864086943	0.667111237300137	0.187686609067277	NA	NA	0.198464984344124	0.0834518965346038	70.4826110930129
a2517	TP53_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	23	10	1.6094379124341	NA	1.40037138738202	0.633129620484952	0.767241766897067	1.58374463912399	1.10164241302447	0.525411144070405	0.484447901475739	0.696452640009261	0.187822064393544	NA	NA	0.808765617149802	0.122839539564179	70.4826110930129
a2518	PIK3CA_mut	288	KIN001-055	JAK3, MNK1	6	26	2.32630161961136	NA	3.29812482992926	3.91703304016183	-0.618908210232576	1.14211262851865	0.980586231648973	0.613202936783423	0.541897703237301	0.631161432066824	0.187849076878093	NA	NA	0.71062161975539	0.260531043223983	70.4826110930129
a2519	loss_cnaOV16, loss_cnaOV17	179	5-Fluorouracil	DNA antimetabolite	6	25	3.46573590279973	NA	4.87424412466462	3.66938653345849	1.20485759120613	1.45860295194371	1.6966204048158	0.726683533758979	0.826035344025979	0.71015153878038	0.187915238282876	NA	NA	0.137703812465821	0.114238333877652	70.4826110930129
a2520	loss_cnaOV38	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	8	24	1.63315443905142	NA	2.4477809073697	3.00242946922892	-0.554648561859226	0.561295254604877	0.824316776606469	0.719376557208861	0.988158295137681	0.672858514590218	0.187942930285436	NA	NA	0.016953092970491	0.0471624290731107	70.4826110930129
a2521	SMARCA4_mut	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.81844609143877	5.71934372143844	1.09910237000033	0.498079032621211	1.29148776771891	0.87626336711813	2.20668267085275	0.851035834386275	0.187945286063335	NA	NA	0.561671488942395	0.0285765791268005	70.4826110930129
a2522	PTEN_mut	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	4.65554907249876	3.24264093350412	1.41290813899463	0.779109089338489	1.6721459936335	0.867920494748266	1.81349204922545	0.844966973203363	0.187980353344151	NA	NA	0.621485382467965	0.0569414133271597	70.4826110930129
a2523	loss_cnaOV34	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.5761349278389	1.51832551342659	1.05780941441232	0.970140992176286	1.50240379512354	0.733151446952136	1.09036668169167	0.704077970147387	0.18808637582997	NA	NA	0.314998639887276	0.0765711826932194	70.4826110930129
a2524	loss_cnaOV85	211	TL-2-105	CRAF	7	25	2.32630161961136	1.63315443905142	4.18477604306181	4.4719748582503	-0.287198815188488	0.899776653046153	0.535127263725098	0.459292669249225	0.319189005645112	0.536692548963504	0.188107396300779	NA	NA	0.259894806569654	0.446186413063817	70.4826110930129
a2525	KRAS_mut	1149	TW 37	BCL2, BCL2L1	7	26	1.6094379124341	NA	-1.24197857573205	-0.605349992755834	-0.636628582976218	0.886622613328431	0.892759547250806	0.714049347553306	0.718037836398372	0.713101960025713	0.188201680595705	NA	NA	0.0376547082306743	0.124558508779099	70.4826110930129
a2526	gain_cnaOV94	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	4.34731759580149	3.87695306768788	0.470364528113612	0.509033068610182	0.788499932675428	0.634696172006604	0.924035307564305	0.596530841185536	0.188204994951508	NA	NA	0.5156307881099	0.0780395748522508	70.4826110930129
a2527	loss_cnaOV58	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.33479227659251	5.87801353970305	0.456778736889466	0.711692844234412	0.684223873293595	0.66408676942463	0.641820050025704	0.667586669682696	0.188247766790702	NA	NA	0.906564607258114	0.236976001848767	70.4826110930129
a2528	loss_cnaOV83	281	CH5424802	ALK	5	27	1.63315443905142	NA	4.32676847980475	3.85368661390075	0.473081865903999	0.615624810172726	0.727868585854325	0.662651024918585	0.768458090198259	0.649955053835338	0.188279601856041	NA	NA	0.95471511490356	0.174389440270693	70.4826110930129
a2529	loss_cnaOV54	1052	RO-3306	CDK1	11	22	1.6094379124341	NA	3.78413077492136	3.33061855749627	0.453512217425092	0.902506855521019	0.877159566604718	0.512202767535754	0.502502795021184	0.517023623399027	0.188391232691428	NA	NA	0.78950462246012	0.185102177395519	70.4826110930129
a2530	KRAS_mut	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	3.72708220424753	3.24313999221898	0.483942212028551	0.178359072040534	1.03436351962206	0.49709566301547	2.71330303803425	0.467864733092458	0.188434491856684	NA	NA	0.171700383281775	0.100232483555657	70.4826110930129
a2531	loss_cnaOV33_(ZFHX3)	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.80778603890518	2.21786689863341	0.58991914027177	0.826916839759995	0.891413946209027	0.666605547025165	0.713395969107352	0.661779123807247	0.188441219879085	NA	NA	0.585197335840172	0.256242812997796	70.4826110930129
a2532	gain_cnaOV95_(MECOM)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	24	2.99573227355399	NA	4.61369585988791	3.83902124555484	0.774674614333076	1.92860337709199	1.29818436436625	0.527107129969174	0.401676479225684	0.596736977887771	0.188448909084027	NA	NA	0.318325260351911	0.316601040679178	70.4826110930129
a2533	loss_cnaOV21, loss_cnaOV22	262	VX-11e	ERK	3	29	1.63315443905142	NA	1.9853285568367	2.94968610769014	-0.964357550853441	0.618074017797784	1.11781419106639	0.883403355674996	1.56026223896205	0.862717219517001	0.188588419110756	NA	NA	0.379529788543735	0.087966673394284	70.4826110930129
a2534	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.6900756352009	0.692763136708399	0.997312498492498	0.539260941556878	1.38326079061708	0.763996134088281	1.84940614392208	0.72098660300173	0.188666744402619	NA	NA	0.153986233413789	0.0129034186859587	70.4826110930129
a2535	TP53_mut	177	GSK-650394	SGK3	12	7	2.77258872223978	NA	3.5787336016857	4.59549437876047	-1.01676077707477	1.70027764558296	0.97439928974977	0.684611759170237	0.597996909337803	1.04347446449379	0.188995267230126	NA	NA	0.73198292597233	0.115873060769463	70.4826110930129
a2536	loss_cnaOV52, loss_cnaOV53	283	GSK2126458	PI3K, MTOR	8	24	-2.05572501506252	0.0237165266173161	-3.39016302196768	-2.51285628070148	-0.877306741266199	1.3835448817848	1.8342944018225	0.504315885528981	0.634100673434214	0.478280226115575	0.18906793172642	NA	NA	0.689317054257437	0.173677129250944	70.4826110930129
a2537	loss_cnaOV44	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.88583515861844	2.71421966579127	1.17161549282717	1.04708786196451	1.38337648076556	0.859245417180633	1.11892758514938	0.84692454231895	0.189190635085121	NA	NA	0.619186788503982	0.17966329630785	70.4826110930129
a2538	gain_cnaOV26	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.93658491150213	1.8361813746526	1.10040353684953	2.09582428813818	1.23694629420689	0.838838760431328	0.52504570305704	0.889613026857482	0.189246494571482	NA	NA	0.83521661879158	0.460301881706577	70.4826110930129
a2539	SMAD4_mut	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.292373055558167	-0.802188193777358	0.509815138219191	1.24903411506103	0.871850861487156	0.557070350236159	0.408167504851765	0.584750397963221	0.189274730887104	NA	NA	0.0376799915424026	0.480624959167557	70.4826110930129
a2540	loss_cnaOV82	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.806184114401987	0.0134754204588315	-0.819659534860819	1.33190885150192	0.906137140558826	0.871479823562504	0.615402123003038	0.904564550080493	0.189289860917071	NA	NA	0.539388528069026	0.398654602340974	70.4826110930129
a2541	loss_cnaOV16, loss_cnaOV17	1025	SB 216763	GSK3A, GSK3B	5	18	2.30258509299405	NA	5.43629715515996	4.82763911069365	0.608658044466312	0.970483374734977	0.744530594303956	0.767973004426787	0.627169985918127	0.817505753454405	0.18931143659279	NA	NA	0.438439842505406	0.246457846454634	70.4826110930129
a2542	loss_cnaOV20	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	0.923873575934246	-0.0960012242990885	1.01987480023333	1.48516451484175	1.22509440247993	0.79999583215234	0.686708300690852	0.832486703203301	0.18952611815384	NA	NA	0.864099791349408	0.272590211650542	70.4826110930129
a2543	gain_cnaOV26	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.5767350195363	3.72073803328187	0.855996986254421	0.976855326109918	1.0093773104641	0.849842555893024	0.876278158469193	0.848044608671506	0.189632141727562	NA	NA	0.710688979853778	0.263808865193582	70.4826110930129
a2544	gain_cnaOV94	1494	SN-38	TOP1	7	25	-2.99573227355399	NA	-4.64218356354733	-4.05499779921524	-0.587185764332093	0.987993218379192	1.39890649469489	0.442510176480054	0.594321654652017	0.419746256493122	0.189672562195771	NA	NA	0.207126262377654	0.229482569986633	70.4826110930129
a2545	NF1_mut	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-4.82798295626576	-3.52275086145306	-1.30523209481269	1.11581704280577	1.73751027200075	0.775135892396842	1.16975457869924	0.751208275338548	0.189687947707384	NA	NA	0.23386546443608	0.0962639660155684	70.4826110930129
a2546	gain_cnaOV72_(ASXL1)	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	0.611396386163541	1.74193560558268	-1.13053921941914	1.73776948311428	1.55281888191824	0.7161061472173	0.650569152240543	0.728056074397133	0.189718185988548	NA	NA	0.072233145456392	0.229948452463273	70.4826110930129
a2547	gain_cnaOV50	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-4.87838857726175	-4.08416698629162	-0.794221590970126	0.495170426565113	1.38464521840494	0.60036865460972	1.60393583372792	0.573592123392476	0.18976664052303	NA	NA	0.207131924520782	0.0480772613419579	70.4826110930129
a2548	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1028	VX-702	p38	4	27	0.693147180559945	NA	3.94005254645085	3.23614206240241	0.703910484048444	0.745283249462506	0.917394462288375	0.781154499919186	0.944487192696335	0.76729314704232	0.189888064109565	NA	NA	0.507769240252993	0.155398792748599	70.4826110930129
a2549	loss_cnaOV20	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	3.11455158924909	1.94476989335108	1.16978169589801	1.76724616268374	1.2182082114243	0.900119141566716	0.661923460691849	0.960247751515593	0.190017896606184	NA	NA	0.887119367801573	0.371082598736831	70.4826110930129
a2550	gain_cnaOV72_(ASXL1)	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	7.71801340252003	6.42554266306583	1.29247073945419	1.4020545843278	1.43675710248654	0.903387079114888	0.921840528822101	0.899574978413095	0.19007952165591	NA	NA	0.316453144140097	0.166117159595106	70.4826110930129
a2551	SMARCA4_mut	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.52610033383581	1.63750213578388	0.888598198051934	1.33746345443134	1.60658664856836	0.55904611002628	0.664390638194855	0.553096964202813	0.190174700620841	NA	NA	0.0367637751403545	0.371583203102808	70.4826110930129
a2552	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.42819304670715	2.06864537091016	1.35954767579699	3.36973094026065	1.43805835356272	0.764731650586054	0.403458822054152	0.945405082087784	0.190197162951484	NA	NA	0.388907532523051	0.558909764589663	70.4826110930129
a2553	SMAD4_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.26446990256653	1.28229238400675	0.982177518559784	2.58068762109406	1.24232603464139	0.682219934962005	0.380587526569139	0.790595617553244	0.190329522154696	NA	NA	0.465635396806722	0.50527028216686	70.4826110930129
a2554	gain_cnaOV51_(MYC)	170	Shikonin	unknown	5	13	2.77258872223978	NA	0.344473601115418	-0.148109740216073	0.492583341331491	0.856561601352165	0.736236999674081	0.641311641678686	0.575070538480712	0.669055401385082	0.190408739860015	NA	NA	0.566544977898294	0.297045900441114	70.4826110930129
a2555	gain_cnaOV18_(CCNE1)	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	6.14220398805912	5.66708440787265	0.475119580186471	0.55094568323565	0.591293045043765	0.808875213521004	0.862371000705805	0.803526414134136	0.190481647064087	NA	NA	0.182200612591286	0.184246329381544	70.4826110930129
a2556	loss_cnaOV83	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	3.07169696524758	2.17365005116194	0.898046914085648	0.468951907658476	1.51060829180424	0.633906504155987	1.91500855294456	0.594493568556438	0.190502897797779	NA	NA	0.816725464628287	0.0202246717229481	70.4826110930129
a2557	gain_cnaOV18_(CCNE1)	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.86379836881701	2.28450488625539	0.57929348256162	1.16312121319196	0.810261854174775	0.679803499671195	0.498050827369797	0.714946013534861	0.190538339307627	NA	NA	0.642784996041766	0.398320076369441	70.4826110930129
a2558	gain_cnaOV96	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.92098423482198	2.05503066020067	0.865953574621306	0.80636348951083	1.32199995385426	0.677404699799577	1.07389978078822	0.655032984000215	0.190638776659583	NA	NA	0.679187609787407	0.121267848109901	70.4826110930129
a2559	loss_cnaOV20	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	4.78064457120714	3.71272418193288	1.06792038927426	1.79114214286694	1.51010316312855	0.688139170702811	0.596223138139627	0.707183731117948	0.190773425079632	NA	NA	0.708869774632071	0.264910688251811	70.4826110930129
a2560	ARID1A_mut	294	MPS-1-IN-1	MPS1	8	23	2.99573227355399	NA	4.6975602187694	4.13994979364071	0.557610425128688	0.65092668437342	0.825039597063553	0.708932738633659	0.856640906748879	0.675858985572708	0.190841890167913	NA	NA	0.305218758129258	0.0707452235466927	70.4826110930129
a2561	loss_cnaOV40	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	2.20611342032762	1.06665472156783	1.13945869875979	1.74834293692574	1.29613179643463	0.814875278846751	0.651736381172102	0.879122556744759	0.190866866083221	NA	NA	0.849259895458025	0.293357946103688	70.4826110930129
a2562	loss_cnaOV43_(NF1)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-1.07837740809829	-2.15255730052972	1.07417989243144	1.68184229375115	2.05516364138821	0.534180961001768	0.638692400840752	0.522673655177092	0.190947307813636	NA	NA	0.267574087744203	0.248978992084209	70.4826110930129
a2563	loss_cnaOV20	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.70945512712158	0.804806140254843	0.904648986866738	0.541196161728212	1.29947199736448	0.729203703382454	1.67157317594032	0.696166588200054	0.191003343097126	NA	NA	0.956378768204083	0.0357789508789423	70.4826110930129
a2564	loss_cnaOV16, loss_cnaOV17	219	AT-7519	CDK9	6	26	2.32630161961136	NA	0.806274617338183	1.65726918807396	-0.850994570735773	1.21173476625537	1.76354000141735	0.505288755425879	0.702294424848112	0.482549060441971	0.191004022849648	NA	NA	0.304879278034984	0.187301152771237	70.4826110930129
a2565	loss_cnaOV35	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.61218573637119	3.34405381994963	-0.731868083578436	1.19877607243598	1.21220534033679	0.604638092567468	0.610512755807043	0.603749265264826	0.191042417683548	NA	NA	0.592289135535597	0.260170819449204	70.4826110930129
a2566	loss_cnaOV83	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	3.32030399033314	2.70457377760345	0.61573021272969	1.22644955182567	0.893255367848807	0.653026037704986	0.502042837239513	0.689310397554654	0.191043029663361	NA	NA	0.965413249017713	0.334380047237141	70.4826110930129
a2567	loss_cnaOV20	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	2.67221965076559	1.03390642656275	1.63831322420284	2.54781983019247	2.21782826530049	0.723442585550178	0.643025540812702	0.738701571188094	0.191349640519646	NA	NA	0.35229708491273	0.234007340878308	70.4826110930129
a2568	loss_cnaOV83	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	6.1268225962942	5.42984268811924	0.696979908174963	0.740207319624333	0.982064780186366	0.73107064163159	0.94160094029966	0.709708689525244	0.191364555208892	NA	NA	0.292997056948143	0.110686243381296	70.4826110930129
a2569	gain_cnaOV18_(CCNE1)	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	7.50658863136212	8.89153574301076	-1.38494711164865	0.583870028896228	1.72414140577887	0.828973397367992	2.37201267937456	0.803267705889241	0.191393066018831	NA	NA	0.91986454167874	0.0211854262477103	70.4826110930129
a2570	TP53_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	21	10	3.68887945411394	NA	3.67572181826392	3.09877785808778	0.576943960176134	1.0998407070227	1.06200939663737	0.530162083223529	0.5245704732442	0.543256925977214	0.191482406043732	NA	NA	0.720333830821173	0.178844465500241	70.4826110930129
a2571	loss_cnaOV102	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.84920826204387	0.822783532184468	1.0264247298594	0.2218461456199	1.28584663777971	0.827434523875198	4.62674132557629	0.798248173383842	0.191492924977216	NA	NA	0.956381864359731	0.001329557720272	70.4826110930129
a2572	gain_cnaOV72_(ASXL1)	1527	GDC0941 (rescreen)	PI3K	5	26	1.38629436111989	NA	0.880464980048303	0.286476696322415	0.593988283725888	0.7303159581877	0.913802118293433	0.666845373584969	0.813330555174895	0.65001850163708	0.191691461170214	NA	NA	0.90743142751902	0.156954125478187	70.4826110930129
a2573	loss_cnaOV35	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.55720472248705	0.741854118700797	0.815350603786254	2.25600810405739	0.964948112151742	0.668953159998054	0.361412976451574	0.844968339248936	0.191727189936148	NA	NA	0.841248155675819	0.468535395319446	70.4826110930129
a2574	loss_cnaOV83	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.49053379077082	2.80290359433815	0.687630196432663	0.817965367603944	0.818193211329081	0.840458634734744	0.840659303763593	0.840425203865565	0.191742824389276	NA	NA	0.313672358616272	0.195341562983537	70.4826110930129
a2575	loss_cnaOV16, loss_cnaOV17	292	Masitinib	KIT	6	26	2.99573227355399	NA	4.61092391841329	3.8756580746785	0.735265843734786	0.637803797614823	1.07633622271922	0.723350806566462	1.15280882065055	0.683119111124249	0.191756066721934	NA	NA	0.0970344898349602	0.0476142383841752	70.4826110930129
a2576	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.90281483254471	2.22875378289602	0.674061049648691	1.2135736364101	0.855205856121652	0.762000264051043	0.555434816170405	0.788185727241801	0.191812733599716	NA	NA	0.585374505792765	0.439027088822856	70.4826110930129
a2577	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.32325121375452	4.03076010750779	1.29249110624673	0.796948788946358	1.45176187586146	0.911778400568834	1.62179944831277	0.890291395398288	0.191917470290688	NA	NA	0.0863711039004044	0.0800009245014793	70.4826110930129
a2578	loss_cnaOV83	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	3.48544785673976	2.50191207015805	0.983535786581707	1.61917599304551	1.19754961229092	0.767146926226281	0.607429822827211	0.821290221705471	0.19202114649527	NA	NA	0.938528884146666	0.320990637910594	70.4826110930129
a2579	PIK3CA_mut	1495	AZD-2281	PARP1, PARP2	7	26	2.30258509299405	NA	2.97161707661743	3.71998000153955	-0.748362924922116	0.530490189893339	0.932186892588864	0.861124931006139	1.4107007804849	0.802803526708862	0.192111565348076	NA	NA	0.134271562453989	0.0133057457964081	70.4826110930129
a2580	gain_cnaOV95_(MECOM)	151	QS11	ARFGAP	5	14	2.32630161961136	NA	4.24214703898059	3.59700534679929	0.645141692181296	1.02206939594587	1.55531146028591	0.445655797873789	0.631211241370017	0.414799034569386	0.192177757863718	NA	NA	0.0547768597525643	0.318732318128963	70.4826110930129
a2581	TP53_mut	238	CAL-101	PI3Kdelta	22	10	2.99573227355399	2.32630161961136	4.53792204680369	4.0556821422529	0.482239904550792	0.975207316084447	0.945435577376017	0.499020927781453	0.494499883867805	0.510071670762815	0.192194793127442	NA	NA	0.501573649573699	0.201985882690863	70.4826110930129
a2582	NF1_mut	272	AR-42	HDAC	4	26	1.63315443905142	NA	1.49876351468128	0.10991843034629	1.38884508433499	2.11416683671509	1.7519908834974	0.774033609343112	0.656923124616277	0.792723921920484	0.192242277346857	NA	NA	0.475079298438825	0.285377442829979	70.4826110930129
a2583	BRCA1_mut	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.87101152984208	4.46547528767575	0.405536242166333	0.76261684809657	0.565282853241338	0.689682819457408	0.531769319257132	0.717404109891152	0.192291943785756	NA	NA	0.60671806345654	0.371500317811969	70.4826110930129
a2584	loss_cnaOV102	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	3.06142583302033	2.07091025948732	0.990515573533009	0.739487051088606	1.30881219795697	0.775221878067064	1.33946304005576	0.756804967954291	0.192341849517963	NA	NA	0.679259431305547	0.124280961417361	70.4826110930129
a2585	gain_cnaOV49	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	3.45990640991394	4.3926890087813	-0.93278259886736	0.449813961732669	1.3298581793164	0.722354440464319	2.07370752849536	0.701415093259678	0.192572980056206	NA	NA	0.360385874190776	0.0357260698355703	70.4826110930129
a2586	SMARCA4_mut	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	2.37169673616822	3.36975926304975	-0.99806252688153	1.00571950166168	1.00596868921061	0.992157129634863	0.992386570243995	0.992140747108852	0.192591861114376	NA	NA	0.0848362889755633	0.220910885477136	70.4826110930129
a2587	loss_cnaOV82	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.40192214975549	5.74746837489459	-0.345546225139105	0.476707311007717	0.470109404559767	0.734342049309822	0.724860343359642	0.735033636399365	0.192600373081429	NA	NA	0.370690688160607	0.335398130433285	70.4826110930129
a2588	loss_cnaOV85	255	CP724714	ERBB2	7	25	2.32630161961136	NA	4.80981946736741	4.30453957523927	0.505279892128135	0.801965811833752	0.963772708604962	0.54118341905662	0.63005166139536	0.52427287846687	0.192750503109955	NA	NA	0.781530091555323	0.186277397331077	70.4826110930129
a2589	loss_cnaOV44	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.78804192612874	0.774205484102434	1.0138364420263	2.9051419564494	0.994591473233464	0.831706284823787	0.348980000710668	1.01934962173994	0.192848819062307	NA	NA	0.841271698865055	0.607704892215436	70.4826110930129
a2590	loss_cnaOV52, loss_cnaOV53	292	Masitinib	KIT	8	24	2.99573227355399	NA	4.5257594445841	3.842774078977	0.682985365607097	1.01541299047925	1.01329646087824	0.673694636216777	0.672618306059627	0.674023241939624	0.192896465948206	NA	NA	0.0970832056807482	0.125145365520891	70.4826110930129
a2591	gain_cnaOV4_(KRAS)	287	KIN001-244	PDPK1 (PDK1)	8	24	2.99573227355399	NA	3.9104677855503	3.42234096841668	0.488126817133625	0.997778540986559	0.847807884522024	0.551507811119837	0.489213585061657	0.575751683895722	0.192961241070071	NA	NA	0.655840104770574	0.240946746300944	70.4826110930129
a2592	loss_cnaOV34	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	5	26	2.30258509299405	NA	2.26887251145312	1.24366967004549	1.02520284140763	2.12716119944563	1.28002366403061	0.71838827350161	0.481958227554552	0.80092491273123	0.192982960656581	NA	NA	0.465798946298507	0.349325503074403	70.4826110930129
a2593	PIK3R1_mut	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.24488112171198	0.668150187525715	0.576730934186263	0.820600968563557	1.06326590361064	0.557655967929863	0.702815322282422	0.542414585314738	0.193035197967586	NA	NA	0.766698251481851	0.213600329102538	70.4826110930129
a2594	PTEN_mut	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.857222859014543	0.311919539576523	0.54530331943802	1.28167660133758	0.844093646658602	0.606371216908705	0.425460930525635	0.646022300483647	0.193125301116936	NA	NA	0.907449771390329	0.463426903095642	70.4826110930129
a2595	loss_cnaOV43_(NF1)	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.0052847717531	4.51005306760405	-0.504768295850949	0.5508818516614	0.741979209124916	0.701614410579638	0.916291386852957	0.680299784203211	0.193264602166563	NA	NA	0.514677235966357	0.119467415314859	70.4826110930129
a2596	gain_cnaOV49	1026	17-AAG	HSP90	3	30	0	NA	-1.78128968914088	-0.405786405204966	-1.37550328393591	1.88736181848274	2.30393748096892	0.603460237918948	0.728796815992434	0.597022833865024	0.193281569737409	NA	NA	0.0559247520508076	0.334254446061401	70.4826110930129
a2597	loss_cnaOV44	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.56319262955758	3.91949903359085	0.643693595966732	1.21961653436112	0.696541485762266	0.866390562039041	0.527783592491159	0.924128151910866	0.193362118472752	NA	NA	0.51592167270003	0.458201722305826	70.4826110930129
a2598	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	281	CH5424802	ALK	7	25	1.63315443905142	NA	4.25016665839484	3.83728857462321	0.412878083771628	0.57390480474875	0.745159932508611	0.578097348949098	0.719419109851123	0.554079823349677	0.193375463149548	NA	NA	0.954746294564073	0.142016115442719	70.4826110930129
a2599	loss_cnaOV41	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.64731112879847	-4.79691037165158	1.14959924285311	1.97069880597282	1.29052935476462	0.835121101817197	0.583345988422427	0.890796663097048	0.193472506426188	NA	NA	0.126504707771038	0.331519473024964	70.4826110930129
a2600	loss_cnaOV42	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.64731112879847	-4.79691037165158	1.14959924285311	1.97069880597282	1.29052935476462	0.835121101817197	0.583345988422427	0.890796663097048	0.193472506426188	NA	NA	0.126504707771038	0.331519473024964	70.4826110930129
a2601	loss_cnaOV58	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.63053624389575	2.96737805113285	0.663158192762908	0.868393012059526	0.89668829271892	0.742545462828448	0.763661364789346	0.739563790614567	0.193555478607037	NA	NA	0.228594771226273	0.171743388766453	70.4826110930129
a2602	loss_cnaOV40	341	EX-527	SIRT1	7	24	2.99573227355399	NA	6.06851011598714	5.68721415973643	0.381295956250713	0.609934593664611	0.526736115992432	0.69963503882936	0.625142368069024	0.723884208190865	0.193685329046251	NA	NA	0.102597350123199	0.168928365863312	70.4826110930129
a2603	gain_cnaOV50	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	3.33416108815829	3.97936439373373	-0.645203305575443	1.0765905833369	1.05978628583793	0.607865681579557	0.599302386219684	0.608805109291738	0.193729768119132	NA	NA	0.305718133531245	0.325546866023306	70.4826110930129
a2604	loss_cnaOV59	1026	17-AAG	HSP90	4	29	0	NA	-1.54254361741416	-0.391285750134999	-1.15125786727916	2.40994418366304	2.26886966938384	0.504295550672074	0.477711423809529	0.507414719679253	0.19381343309915	NA	NA	0.0559405387470663	0.420975181890071	70.4826110930129
a2605	gain_cnaOV94	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.63709295583627	2.53494960073881	1.10214335509746	0.529816654708575	1.35074133566757	0.859874939501533	2.08023538954942	0.815954414064594	0.19399305266818	NA	NA	0.93855854908746	0.0411412154405544	70.4826110930129
a2606	RB1_mut	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.39091868270176	2.08775150178416	0.303167180917591	0.230999298309067	0.572061425261471	0.544870290699953	1.31241602522951	0.529955643800005	0.194046303525056	NA	NA	0.0381491004603083	0.132667913621986	70.4826110930129
a2607	PIK3R1_mut	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-1.49114900971601	-0.71532931129666	-0.775819698419346	0.510138897044503	0.792050018528622	1.01057329408979	1.52080090915253	0.979508465716059	0.194098853347161	NA	NA	0.072113955167409	0.0438812796632764	70.4826110930129
a2608	gain_cnaOV95_(MECOM)	1033	Vismodegib	SMO	8	23	2.30258509299405	NA	5.26667517670854	4.78721050545768	0.479464671250858	0.597387738474826	0.90346311459819	0.570887425098826	0.802602129857847	0.530696454015277	0.194258288419296	NA	NA	0.144800868145733	0.106756711764032	70.4826110930129
a2609	loss_cnaOV40	1072	BMS-708163	g-secretase	8	25	1.6094379124341	NA	4.1767405298935	3.73405953239195	0.442680997501544	1.12078608257941	0.752067080081653	0.521148595335955	0.394973674621962	0.58861903309673	0.194260619117775	NA	NA	0.922021355135157	0.323210138038251	70.4826110930129
a2610	loss_cnaOV35	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	-0.825456196107683	0.29952215562903	-1.12497835173671	1.05704126543765	1.64842755638025	0.711979259235958	1.06427098782273	0.682455439053102	0.19429229961645	NA	NA	0.451154388698919	0.0836738071693104	70.4826110930129
a2611	KRAS_mut	293	MP470	PDGFR	7	25	2.99573227355399	NA	3.37488010477659	4.23806426191651	-0.863184157139923	2.89255748013609	1.30584655723134	0.495268382050956	0.298415558918923	0.661014996256566	0.194522597593521	NA	NA	0.614105180023525	0.468729616355647	70.4826110930129
a2612	loss_cnaOV57_(ZNRF3)	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	1.07887901530342	0.577128282242985	0.50175073306043	0.702016640596431	0.585608712047304	0.838669911510053	0.714727691688539	0.856802029645863	0.194537236676305	NA	NA	0.0130895740094492	0.251363696062999	70.4826110930129
a2613	loss_cnaOV83	192	LFM-A13	BTK	4	15	2.77258872223978	NA	5.1326177750732	4.61640992679199	0.516207848281213	0.567936876650091	0.682375180909091	0.77787162376404	0.908917644731936	0.756486845833838	0.194643882599674	NA	NA	0.955035674840642	0.177076495495289	70.4826110930129
a2614	gain_cnaOV95_(MECOM)	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-5.17735340569292	-3.83883718175717	-1.33851622393575	1.16238269175878	2.51494793220178	0.583668386775282	1.15152800659003	0.53222422889841	0.194746314836868	NA	NA	0.926234987281952	0.0628085030150341	70.4826110930129
a2615	ARID1A_mut	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	1.99361621891873	2.60680218088717	-0.613185961968434	0.760989459072032	0.828644624160507	0.754010845851418	0.805774580263132	0.739986653011414	0.194804371634842	NA	NA	0.606919932141841	0.170989311618725	70.4826110930129
a2616	loss_cnaOV84	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	6	26	0.246860077931526	2.32630161961136	0.236098318645341	1.18142684739216	-0.945328528746819	0.757322218730041	1.62450821763092	0.624039912826918	1.248251411839	0.581916741625	0.194842698370159	NA	NA	0.786238298305127	0.0478315349742322	70.4826110930129
a2617	loss_cnaOV35	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	1.06931560598259	-0.0595294299185688	1.12884503590116	1.71433424273956	1.20600305875315	0.884426513891934	0.65847429734427	0.936021702190572	0.194861628388077	NA	NA	0.864276545734998	0.373085299430207	70.4826110930129
a2618	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	0.405443763710547	-0.464354227131218	0.869797990841765	0.903005044147466	1.4391813171188	0.629495425014554	0.963226060008278	0.604369984862696	0.194994350678059	NA	NA	0.886482802181036	0.110921169756388	70.4826110930129
a2619	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	4.98063898176825	4.11596816899256	0.864670812775691	1.55884686395611	0.886964466605986	0.913343203514321	0.554686180386758	0.974865223275964	0.19503876300793	NA	NA	0.0434617338147253	0.438887661293625	70.4826110930129
a2620	loss_cnaOV40	1262	UNC1215	LMBL3	8	25	0	NA	3.0258868721959	2.70186097088949	0.324025901306411	0.659950680118436	0.409668988052777	0.678183546921938	0.49098502519652	0.790945643326721	0.195198710961548	NA	NA	0.102254251227625	0.223290293583959	70.4826110930129
a2621	gain_cnaOV18_(CCNE1)	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-2.31977675602468	-3.83810267200792	1.51832591598324	0.235110170678854	1.74064328039634	0.903397918368441	6.45793379163159	0.872278618533211	0.195237802494701	NA	NA	0.234216774170711	0.000223876029667785	70.4826110930129
a2622	gain_cnaOV19	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-2.31977675602468	-3.83810267200792	1.51832591598324	0.235110170678854	1.74064328039634	0.903397918368441	6.45793379163159	0.872278618533211	0.195237802494701	NA	NA	0.234216774170711	0.000223876029667785	70.4826110930129
a2623	loss_cnaOV87, loss_cnaOV88	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.31558046688754	4.03155363304575	1.28402683384179	0.810092906128265	1.45197152175648	0.905362218608542	1.58503651140291	0.884333345800389	0.195426731240693	NA	NA	0.0865106405672628	0.0849029764560483	70.4826110930129
a2624	loss_cnaOV52, loss_cnaOV53	211	TL-2-105	CRAF	8	24	2.32630161961136	1.63315443905142	4.70039989888629	4.31206685694166	0.388333041944633	0.774899647045513	0.554555634949647	0.633399043005118	0.501139784261412	0.70025984314431	0.195545869230392	NA	NA	0.260361219720421	0.220948881660502	70.4826110930129
a2625	SMARCA4_mut	1248	FK866	NAMPT	3	29	0	NA	-4.02429842553442	-1.46877767927552	-2.55552074625889	1.80108011315242	2.72352156993775	0.95642485337064	1.41888232932958	0.938314854733207	0.195546189786865	NA	NA	0.0401498940274272	0.112748955946786	70.4826110930129
a2626	loss_cnaOV70	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.10881225835686	2.86677163164972	-0.75795937329286	0.820884481524953	0.951478509243322	0.803264563478694	0.923344746248343	0.796612184016262	0.195587630430305	NA	NA	0.965433469575038	0.244679552751627	70.4826110930129
a2627	loss_cnaOV39	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	9	23	1.63315443905142	NA	2.47600176384854	3.01550168025282	-0.539499916404285	0.551743046060661	0.835612883177068	0.700455543845595	0.977810087967959	0.645633794387016	0.195619512504081	NA	NA	0.0170564560834778	0.0444980938996421	70.4826110930129
a2628	loss_cnaOV54	1243	piperlongumine	Increases ROS levels	10	22	2.30258509299405	NA	1.90087817597165	1.48429061872297	0.416587557248687	0.628016346158856	0.673046465103305	0.631327026485786	0.663338716892746	0.618958094051864	0.195723348729408	NA	NA	0.198936919467939	0.10567862785314	70.4826110930129
a2629	loss_cnaOV41	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.991190291364727	0.15432653556844	0.836863755796286	0.883783102551856	1.13470850861882	0.756975612751784	0.946910789966346	0.737514303840838	0.195728718942961	NA	NA	0.138246808849442	0.107486199076542	70.4826110930129
a2630	loss_cnaOV85	1003	Camptothecin	TOP1	7	24	-2.30258509299405	NA	-2.81084851926883	-3.94792772705891	1.13707920779009	1.82179469838569	1.63178080797333	0.679719347793988	0.62415331914055	0.696833301528004	0.19576422704879	NA	NA	0.234249496257558	0.17126969857631	70.4826110930129
a2631	SMAD4_mut	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.90429466509881	-4.75883873664412	0.854544071545305	1.90633677057529	1.33172596873716	0.609460742404692	0.448265010010495	0.64168161589253	0.195773530349297	NA	NA	0.12661943272893	0.442682401069729	70.4826110930129
a2632	SMARCA4_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	1.094084641249	2.46889101654215	-1.37480637529315	0.619738119213348	1.55445322337041	0.909448882910632	2.21836664983305	0.8844308433497	0.195828013916384	NA	NA	0.231978220118611	0.0285361860545162	70.4826110930129
a2633	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	4.51551440754478	3.25712727815454	1.25838712939025	0.321906921562359	1.69472941266522	0.767602925920927	3.90916455999992	0.742529822156826	0.195838227811029	NA	NA	0.621852080491997	0.00275108469033265	70.4826110930129
a2634	loss_cnaOV41	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.55118660749482	0.742968584440099	0.808218023054724	2.13370559373546	1.00776967130744	0.662738103842594	0.378786101244542	0.801986848846303	0.195877310727762	NA	NA	0.841334459870445	0.449788704519518	70.4826110930129
a2635	loss_cnaOV38	294	MPS-1-IN-1	MPS1	8	23	2.99573227355399	NA	3.91133528401637	4.4134193361635	-0.502084052147136	0.787841655447841	0.796170227352377	0.632214000567134	0.637290562989756	0.630623998358731	0.19591236345909	NA	NA	0.305550992456806	0.146744936612406	70.4826110930129
a2636	loss_cnaOV35	1032	Afatinib	ERBB2, EGFR	5	26	-0.693147180559945	NA	1.2725607124193	0.181044890805186	1.09151582161412	1.26870237901094	1.68963570952881	0.666363077957365	0.860340328568665	0.646006600984133	0.19595151789266	NA	NA	0.833346378759514	0.140245449477991	70.4826110930129
a2637	loss_cnaOV44	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-0.998141308367951	-2.4282659211544	1.43012461278645	0.955883176445299	1.60637166738456	0.909432818648805	1.49612907521266	0.890282517939901	0.19599693120603	NA	NA	0.116422804835814	0.0988005120837941	70.4826110930129
a2638	PTEN_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	0.55056663751696	1.25301970912304	-0.702453071606079	0.232869740734999	1.56193056768768	0.47265132886488	3.01650643569641	0.449733865344607	0.196011537100558	NA	NA	0.808964783646016	0.0320139554932091	70.4826110930129
a2639	BRCA1_mut	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.876640846033344	0.198983829951951	0.677657016081393	0.980648325670595	1.13955516999547	0.602277015787673	0.691029595770728	0.594668019525622	0.196034856066593	NA	NA	0.138261556357371	0.270145952805652	70.4826110930129
a2640	loss_cnaOV52, loss_cnaOV53	1149	TW 37	BCL2, BCL2L1	9	24	1.6094379124341	NA	-0.291651866279106	-0.908670126886004	0.617018260606898	1.02164641082888	0.834978146501153	0.695686673482466	0.603945018615882	0.738963364720882	0.196306921250006	NA	NA	0.0378419246077745	0.130637335404032	70.5536947294064
a2641	loss_cnaOV34	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	9.65425934454175	8.58505653752611	1.06920280701564	1.7013965956547	1.67054548847984	0.638393072790724	0.628426558361722	0.640032141829665	0.196513999648432	NA	NA	0.919920786199235	0.247631569278104	70.6011570241187
a2642	gain_cnaOV72_(ASXL1)	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.83938727406909	2.27310396550892	0.566283308560168	0.805044211744152	0.858752482609184	0.664817922928988	0.7034188933963	0.659425527178221	0.196587796617846	NA	NA	0.599670398077009	0.204245759559659	70.6011570241187
a2643	NF1_mut	255	CP724714	ERBB2	4	28	2.32630161961136	NA	5.01097576706675	4.32994009229595	0.681035674770799	0.377560133169318	0.97176259918703	0.732616062001354	1.80378068270621	0.700825155588977	0.196722622190893	NA	NA	0.78164167661245	0.0264877180904987	70.6045177939892
a2644	loss_cnaOV16, loss_cnaOV17	163	JQ1	BRD4	3	16	0.940007258491471	NA	1.29431437062325	-0.137577004130327	1.43189137475358	2.39849309582793	1.71290304033835	0.792364656651091	0.596996246203203	0.835944207601344	0.196814259570516	NA	NA	0.565965152604037	0.412175528458802	70.6045177939892
a2645	loss_cnaOV34	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	0.422268751898079	1.62759823517523	-1.20532948327715	0.833440796722643	1.85104353413176	0.69021823915657	1.44620888252278	0.651162147757111	0.196894014469386	NA	NA	0.606218944488898	0.0371054679770769	70.6045177939892
a2646	loss_cnaOV40	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	5.80263629354492	4.4828227420427	1.31981355150223	1.97687074145105	1.3581009787663	0.888084131034648	0.667627641923349	0.971808114519692	0.196917140342438	NA	NA	0.107515449007847	0.280187414926076	70.6045177939892
a2647	loss_cnaOV58	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	3.06067204682867	2.17569170272099	0.884980344107681	0.676113008193055	1.49974112779835	0.624173921157319	1.30892370562849	0.590088734451691	0.197037853363494	NA	NA	0.816881624393356	0.0541718910586691	70.6045177939892
a2648	gain_cnaOV96	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	3.40685899289051	1.84690922665337	1.55994976623714	0.879521068447041	2.01530905931846	0.807421436850638	1.77363547298705	0.774049895237749	0.197043628105573	NA	NA	0.124067629126011	0.02602329776256	70.6045177939892
a2649	loss_cnaOV83	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.79123840147782	4.18288503385963	0.608353367618187	1.19957363703516	0.812347390040225	0.696098359212814	0.507141328248743	0.748883267278132	0.197152309960684	NA	NA	0.512047005408348	0.328895756734783	70.6062000531913
a2650	loss_cnaOV83	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	3.93535254272515	2.64207842726204	1.29327411546311	1.50776842621296	1.84562871419405	0.716797229126463	0.857740547539793	0.7007227973411	0.197214332069907	NA	NA	0.335481298112339	0.137159814090706	70.6062000531913
a2651	gain_cnaOV48_(SOX17)	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	2.50544108403516	3.1240981133031	-0.618657029267936	0.971239580322433	0.903271096066999	0.681483137955364	0.636976747861278	0.684907368299149	0.197348447761078	NA	NA	0.228813766613798	0.386025058254234	70.6062000531913
a2652	gain_cnaOV18_(CCNE1)	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.75367041598881	5.11515165253311	0.638518763455695	0.390874894522473	0.749732534578821	0.908579897439783	1.63356299522835	0.85166207148046	0.197513362351904	NA	NA	0.112907362552603	0.041457633036024	70.6062000531913
a2653	gain_cnaOV95_(MECOM)	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	2.83838203195897	2.1254226989896	0.712959332969366	1.7362579977625	0.978573519071565	0.593802408413884	0.410629833750599	0.728570024708819	0.197607039059883	NA	NA	0.369681468035158	0.4244716038926	70.6062000531913
a2654	loss_cnaOV20	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.71272984679718	3.57537384873664	1.13735599806054	0.863905583460603	1.58983927560278	0.75031752238029	1.31652812510432	0.715390552689248	0.197610921712939	NA	NA	0.156271751225175	0.0430592851701647	70.6062000531913
a2655	loss_cnaOV57_(ZNRF3)	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.69548240770593	2.88872060821692	0.80676179948901	0.663038742007742	1.00515075639589	0.825508020423188	1.2167641924604	0.802627659936077	0.197673623979852	NA	NA	0.0812122669377371	0.085854791201601	70.6062000531913
a2656	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1067	CCT007093	PPM1D	8	25	1.88706964903238	NA	4.77394942381608	4.39877714419366	0.375172279622422	0.732498024198675	0.671930024260611	0.546839210951454	0.512181968044005	0.558350224095522	0.197798245495571	NA	NA	0.0752354748335557	0.22479981675212	70.6062000531913
a2657	ARID1A_mut	1022	AZD7762	CHEK1, CHEK2	9	22	0.693147180559945	NA	-1.29364672725622	-0.619803040843994	-0.673843686412225	0.661019568567907	0.780501784949736	0.899122156803387	1.0194005116552	0.863346758977137	0.197816530521117	NA	NA	0.072249848611882	0.025528576457024	70.6062000531913
a2658	loss_cnaOV58	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	1.93624226437638	0.466502179170572	1.46974008520581	1.8416696212812	2.32171460416098	0.649293694326018	0.798047634723623	0.633040806381516	0.197876362951227	NA	NA	0.944595482949792	0.163233486556296	70.6062000531913
a2659	gain_cnaOV51_(MYC)	1022	AZD7762	CHEK1, CHEK2	8	23	0.693147180559945	NA	-0.408798894639552	-0.956873751598149	0.548074856958597	0.829579643237568	0.756433755557986	0.707446926000663	0.660665749727955	0.724551030320306	0.197896771197393	NA	NA	0.0722527502717672	0.127238288180931	70.6062000531913
a2660	NF1_mut	1026	17-AAG	HSP90	4	29	0	NA	-2.06089902108093	-0.319788453077514	-1.74111056800342	3.3877428361754	2.07995138377116	0.777235679400797	0.513944136907701	0.83709195396991	0.197941291198387	NA	NA	0.056061456806857	0.383621675480156	70.6062000531913
a2661	gain_cnaOV94	1371	PLX4720 (rescreen)	BRAF	7	26	2.30258509299405	NA	5.0184093511489	4.39631747555133	0.622091875597571	0.906299342879358	0.973715208871662	0.647313723872697	0.686408834437807	0.638884829906733	0.198175190972739	NA	NA	0.315072561964028	0.143541403190362	70.663067679515
a2662	loss_cnaOV59	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	2.25495491753791	1.41749375242325	0.837461165114659	1.94180791138313	0.784385806294463	0.811111772886174	0.431279098311091	1.06766486389004	0.198395132523716	NA	NA	0.439259571651496	0.454961395340221	70.692090360628
a2663	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	0.277606199879915	-0.72818801455292	1.00579421443283	2.42829452442723	1.75775009156067	0.543878195003484	0.414197785447824	0.572205468377938	0.198459352654998	NA	NA	0.0355033649075293	0.55357695982588	70.692090360628
a2664	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-2.32824902426677	-3.83719492898198	1.50894590471521	2.81652580186455	1.56498154971017	0.897395487608725	0.535747232891062	0.964194053913714	0.198480098960563	NA	NA	0.23441670718012	0.452374268006695	70.692090360628
a2665	gain_cnaOV26	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.80025558828048	4.2285200085375	0.571735579742975	1.06511228687755	0.784855981573424	0.708195215038638	0.536784324795517	0.728459224578756	0.19866313104299	NA	NA	0.305727057554235	0.452593539552257	70.7307298007808
a2666	gain_cnaOV4_(KRAS)	328	SNX-2112	HSP90	8	24	0.940007258491471	NA	1.62252428470031	0.38735732841187	1.23516695628844	3.22827517068824	1.87342094853513	0.545737610939983	0.382608944709354	0.659310955850174	0.199005944411583	NA	NA	0.944603557799126	0.332745985569188	70.777760568625
a2667	gain_cnaOV51_(MYC)	185	OSI-906	IGF1R	5	13	0.940007258491471	NA	1.52128039069882	2.47225748614432	-0.950977095445494	1.68512840045544	1.05969414168117	0.763319336337356	0.564335094695736	0.897407146119349	0.199123275075529	NA	NA	0.672507776809294	0.290111797102318	70.777760568625
a2668	loss_cnaOV43_(NF1)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	1.75664411855472	1.11952638213413	0.637117736420593	0.857806207000619	1.27188288085623	0.519529784080931	0.74272922161326	0.500924846155399	0.199222514805314	NA	NA	0.256768117350782	0.1989585858259	70.777760568625
a2669	TP53_mut	1039	SL 0101-1	RSK, AURKB, PIM3	23	10	2.30258509299405	NA	5.06068113344096	4.65472145488485	0.405959678556108	0.843807933220574	0.692303314764123	0.505696271776995	0.481104363414404	0.586389910171706	0.199240828434688	NA	NA	0.94478892011075	0.163229071727319	70.777760568625
a2670	SMAD4_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	0.275512601568798	1.29095819684003	-1.01544559527123	2.56119746294892	1.29425911681527	0.69288073961671	0.396472981861407	0.784576737438708	0.199247042405061	NA	NA	0.80904075253556	0.489119316605558	70.777760568625
a2671	gain_cnaOV18_(CCNE1)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	2.04424820235282	1.0469946656974	0.997253536655415	0.788433573599275	1.5218176294024	0.679810799417466	1.26485422494486	0.655304234481122	0.199296195777194	NA	NA	0.809041895242091	0.080712495447843	70.777760568625
a2672	loss_cnaOV85	1039	SL 0101-1	RSK, AURKB, PIM3	7	26	2.30258509299405	NA	5.28403254210948	4.84440972397016	0.439622818139316	0.981919183571319	0.755659941915608	0.546499487318639	0.44771792373011	0.581773353004351	0.199317391335732	NA	NA	0.944789444477562	0.303226064483588	70.777760568625
a2673	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.20792340525094	4.63455311165124	0.573370293599702	0.635768262647929	0.667787767068237	0.863378281002972	0.901854224700767	0.85861155575962	0.199442816475107	NA	NA	0.95508725723505	0.253252502351609	70.7898545037984
a2674	gain_cnaOV95_(MECOM)	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.01506067501763	1.69605276269573	-0.680992087678098	0.420882536485013	1.33157418973103	0.54785313381301	1.61800984513489	0.511418810104492	0.199561371313575	NA	NA	0.150897430174854	0.0843177555738138	70.7898545037984
a2675	loss_cnaOV55	1030	KU-55933	ATM	8	25	2.30258509299405	NA	4.59926320292281	4.00754883815723	0.591714364765579	0.842002128046928	1.04742881316141	0.588934468309794	0.702746875638063	0.56492083980355	0.199687584267414	NA	NA	0.520740138080977	0.125427686010531	70.7898545037984
a2676	PTEN_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.3698218218597	3.77615642832603	0.593665393533668	0.343373612921257	0.906417637565305	0.683424439151841	1.72891966998585	0.654957901225633	0.199807977386948	NA	NA	0.93785626277202	0.0718801938010711	70.7898545037984
a2677	loss_cnaOV58	1010	Gefitinib	EGFR	5	25	-0.693147180559945	NA	1.59813401336176	0.790884403532138	0.807249609829619	0.854040806696483	1.29580560647353	0.649775595410047	0.945211989286721	0.622971227934805	0.199935566700593	NA	NA	0.956433812065983	0.117325811221774	70.7898545037984
a2678	gain_cnaOV96	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.53224801198773	3.57947100309445	0.952777008893286	0.922685126615803	1.21709512126602	0.799452656690087	1.03261338175879	0.782828714243969	0.200028660725382	NA	NA	0.188773050768432	0.128078027094082	70.7898545037984
a2679	loss_cnaOV83	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	2.30258509299405	NA	1.44219571902891	2.30610716036775	-0.86391144133884	1.69081233401347	1.19059155178676	0.679526543399436	0.510944605713976	0.725615296062144	0.20011830435333	NA	NA	0.67957801522127	0.326805984533101	70.7898545037984
a2680	loss_cnaOV33_(ZFHX3)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	3.07608618318529	2.17793578639781	0.898150396787477	1.38857767066073	1.38860256456324	0.646802825633168	0.646813221733654	0.646801626115369	0.200182343940624	NA	NA	0.520359160753804	0.294690732418032	70.7898545037984
a2681	ARID1A_mut	310	YM201636	FYV1	8	24	1.63315443905142	NA	2.69912319514789	2.24284769705149	0.456275498096392	0.706829491892416	0.889867161891738	0.536360377750617	0.645524137475916	0.512745629500938	0.200186000896532	NA	NA	0.643205375541012	0.160294462003988	70.7898545037984
a2682	gain_cnaOV48_(SOX17)	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	0.660857438014839	1.65885072301743	-0.997993285002596	0.392471938617705	1.65990453606836	0.621098856446404	2.54283984867186	0.601235350176485	0.20018908895745	NA	NA	0.0726062645989931	0.0215831809321129	70.7898545037984
a2683	loss_cnaOV16, loss_cnaOV17	1375	Temozolomide	DNA akylating agent	6	27	3.40119738166216	NA	6.28493324237827	5.87217559408809	0.412757648290184	0.823826207467196	0.659888482920171	0.599090702262581	0.501025148931815	0.625496063310014	0.200494022627835	NA	NA	0.906710241911713	0.291394720040471	70.7898545037984
a2684	SMAD4_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-3.09511088438464	-1.83734647992362	-1.25776440446101	3.14028804215211	1.84298173815075	0.627143494690732	0.400525170805363	0.682461675243214	0.200594915137454	NA	NA	0.268147947529512	0.486263371151186	70.7898545037984
a2685	gain_cnaOV18_(CCNE1)	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.64385894003211	3.82873718759747	0.815121752434643	0.790515968404783	1.30511610594327	0.64461874483271	1.03112623275595	0.624558802640409	0.2006390385145	NA	NA	0.564832234257152	0.132808897928128	70.7898545037984
a2686	gain_cnaOV48_(SOX17)	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	3.64292072664926	4.28796483690645	-0.645044110257193	0.517661196462331	0.991098507427498	0.666663856103819	1.24607390831183	0.650837535747555	0.200680686793564	NA	NA	0.200055917391599	0.144355080815659	70.7898545037984
a2687	NF1_mut	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-5.56941254499439	-4.51215460628922	-1.05725793870517	1.22909084564999	1.40234751317142	0.763126459694744	0.860195112873083	0.753920072432097	0.200692034529703	NA	NA	0.126859608444416	0.186160499914919	70.7898545037984
a2688	loss_cnaOV85	1028	VX-702	p38	7	24	0.693147180559945	NA	3.76280142780408	3.199851494835	0.562949932969083	0.753688664827653	0.935966147455765	0.624609380630798	0.746926362621911	0.601463989375416	0.200727373573134	NA	NA	0.508391971532146	0.126721331114748	70.7898545037984
a2689	loss_cnaOV1	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.250175668823464	1.31264774286862	-1.06247207404516	1.67199858972837	1.1696315119777	0.879266796409058	0.63545034103035	0.908381881955845	0.200813978751582	NA	NA	0.256859770593102	0.386127070486137	70.7898545037984
a2690	loss_cnaOV39	170	Shikonin	unknown	4	14	2.77258872223978	NA	-0.498621124904684	0.127958991599063	-0.626580116503746	1.06222133619969	0.662695616094216	0.831106898839072	0.589877170746221	0.945502129917011	0.200858209765229	NA	NA	0.567579164299748	0.330519517209621	70.7898545037984
a2691	NF1_mut	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	0.683735628852162	1.87753401066842	-1.19379838181626	1.28826106697066	1.58676679014956	0.765972033914051	0.926674268456684	0.752346462773991	0.200915448850213	NA	NA	0.0370193115183955	0.161693254033242	70.7898545037984
a2692	loss_cnaOV84	262	VX-11e	ERK	6	26	1.63315443905142	NA	2.27175753064969	2.99485913883177	-0.723101608182087	0.56917323540106	1.16807290555688	0.662591075183482	1.27044204331316	0.619055201727625	0.20100212569901	NA	NA	0.380300957342452	0.0411941980072135	70.7898545037984
a2693	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1032	Afatinib	ERBB2, EGFR	8	23	-0.693147180559945	NA	1.02734407461023	0.123966005484762	0.903378069125465	1.41373488516989	1.70523180103497	0.550967219372377	0.63900104510536	0.529768485772534	0.201086342342855	NA	NA	0.833459150294018	0.161934320911993	70.7898545037984
a2694	PIK3CA_mut	1052	RO-3306	CDK1	7	26	1.6094379124341	NA	3.7462235983016	3.41059544619006	0.335628152111541	0.920393254538979	0.89681750027679	0.37232912874314	0.364657335825061	0.374243535622302	0.201132826116652	NA	NA	0.789838394068097	0.410853256597793	70.7898545037984
a2695	gain_cnaOV49	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.32694380491102	4.75847090165933	0.568472903251694	0.433511230401402	0.750583414726358	0.774781183153283	1.31132220663655	0.757374719582557	0.201185698103431	NA	NA	0.760080700717056	0.130375389615221	70.7898545037984
a2696	loss_cnaOV54	1264	SGC0946	Q8TEK3 (DOT1L)	11	22	-0.693147180559945	NA	2.35789003635505	1.99402321371476	0.363866822640293	0.293971541555	0.617700833804098	0.679977074913077	1.23776206606794	0.589066426217083	0.20124203310474	NA	NA	0.0383114073997111	0.0288492453455446	70.7898545037984
a2697	loss_cnaOV40	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	8	25	1.6094379124341	NA	3.07026060412305	2.11147598348108	0.958784620641974	1.69044709332006	1.44945058479952	0.636118947240201	0.567178129638418	0.661481412817248	0.201352237649049	NA	NA	0.232292410039959	0.178042689491962	70.7898545037984
a2698	loss_cnaOV41	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	3.14293841639114	2.42884927208794	0.714089144303206	1.08383508644782	0.998250072361938	0.70722830919865	0.658854057441133	0.715340939183321	0.201426396019724	NA	NA	0.385055530544383	0.225164626359088	70.7898545037984
a2699	loss_cnaOV43_(NF1)	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.97666444406932	3.39341873459665	0.583245709472669	1.12748429026334	0.845094603925027	0.657844984117333	0.51729830252131	0.690154341021461	0.201500639967573	NA	NA	0.78984765116592	0.321979864490929	70.7898545037984
a2700	loss_cnaOV85	165	DMOG	Prolyl-4-Hydroxylase	6	13	8.29404964010203	NA	5.94131352219011	7.04671634022515	-1.10540281803504	0.825442561243893	1.62401778943908	0.769775273225467	1.33916382548686	0.680659303871813	0.201532051172872	NA	NA	0.317748529383769	0.0663041134752113	70.7898545037984
a2701	loss_cnaOV59	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.52975623455353	3.57981469653365	0.949941538019879	1.47311357384782	1.15788897023069	0.796901881763105	0.644852884994196	0.820408141404631	0.201634428409033	NA	NA	0.188857973912069	0.291656219796023	70.7898545037984
a2702	loss_cnaOV43_(NF1)	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	-0.131882402483113	-1.23118411065489	1.09930170817178	1.96828983029791	1.94299048186492	0.56479216146995	0.558506014332958	0.565778226106724	0.20165181081717	NA	NA	0.433504697741951	0.29751484827801	70.7898545037984
a2703	loss_cnaOV41	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.80512840944125	4.08442043699566	0.720707972445597	1.16608061482244	0.904905089896998	0.76353210001848	0.618060160922357	0.796445926199434	0.201685871558268	NA	NA	0.0436300127071582	0.247614035163994	70.7898545037984
a2704	ARID1A_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	8	24	1.63315443905142	NA	3.45314711714735	2.66730739930304	0.785839717844311	0.842978085264921	0.691566758477124	1.07691824883136	0.932218442662536	1.13631794503076	0.20174169929784	NA	NA	0.0171358647296477	0.0376658168108198	70.7898545037984
a2705	SMARCA4_mut	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.45990047288355	3.77952370434321	0.680376768540345	0.519325883742315	0.866093798529204	0.802320112124147	1.31011526642477	0.785569380240058	0.201886861205547	NA	NA	0.922095503346954	0.131295674353459	70.7898545037984
a2706	gain_cnaOV96	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	5.17401984054101	4.18842448727644	0.985595353264567	0.96302209383062	1.30750490144482	0.771061549586752	1.0234400223822	0.753798591634697	0.201932405101595	NA	NA	0.360943376994656	0.13103643646763	70.7898545037984
a2707	gain_cnaOV51_(MYC)	299	OSI-027	MTORC1/2	8	24	2.99573227355399	NA	0.749668748035294	1.79151392424747	-1.04184517621218	1.32445383955651	2.01619780785316	0.554844535377427	0.786622489282857	0.51673758008969	0.201962714329296	NA	NA	0.777849934245225	0.111415491144259	70.7898545037984
a2708	loss_cnaOV20	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.36343000037811	1.2676316287754	1.09579837160271	2.48129488562803	1.25291275189446	0.766402928517467	0.441623596594549	0.874600701402242	0.202128496193176	NA	NA	0.466342920330989	0.445546537063867	70.8218001579633
a2709	loss_cnaOV20	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.77536467702836	4.39203953499586	0.383325142032501	0.534559073002421	0.543502407784221	0.706826621228983	0.717086588540168	0.70528692521393	0.202405709348225	NA	NA	0.354363959831651	0.195232888919953	70.8927511203913
a2710	loss_cnaOV70	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	4.24855622237297	3.40829528918933	0.840260933183639	0.14733486482518	1.13271393417455	0.768314584177581	5.70306922384357	0.741812127345258	0.20262748893571	NA	NA	0.720736032594339	0.00111090174449041	70.9405702982358
a2711	PIK3R1_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.51982194394886	2.26261025884854	-0.742788314899677	0.663087249654549	1.34109156211407	0.576870681550755	1.12019695038119	0.553868457518857	0.202776281616755	NA	NA	0.679683529050093	0.117972464500976	70.9405702982358
a2712	loss_cnaOV70	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	3.23251602635506	3.94675229765173	-0.714236271296664	0.354640086395886	0.893931575160112	0.833110235281388	2.01397500929819	0.798983156142278	0.202830189406734	NA	NA	0.937891049085501	0.041402724052126	70.9405702982358
a2713	loss_cnaOV52, loss_cnaOV53	300	CX-5461	RNA Pol I	8	23	2.32630161961136	NA	4.24328167778099	3.29457107182629	0.948710605954708	1.73909924201443	1.64625100678307	0.568384382979791	0.545518382755317	0.576285512990258	0.20284130344735	NA	NA	0.691919838037426	0.20345737734723	70.9405702982358
a2714	loss_cnaOV59	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	4.61662013962328	3.8166334404573	0.799986699165988	0.969408129326384	1.22391958698962	0.66660199480903	0.825232092619109	0.653626845807453	0.202926055903333	NA	NA	0.692149507272997	0.203347787624649	70.9440614703818
a2715	loss_cnaOV70	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	5.12381165482998	4.31102315474898	0.812788500081007	0.639566182881125	0.981996959883274	0.844048616510142	1.27084345895142	0.827689426021869	0.203282634741312	NA	NA	0.502184435780564	0.140516299291711	71.015137129034
a2716	loss_cnaOV35	163	JQ1	BRD4	3	16	0.940007258491471	NA	1.27636066717651	-0.134210684734063	1.41057135191057	2.47888213713977	1.70057785364018	0.779492737664272	0.569035264233314	0.829465907068687	0.203466586037258	NA	NA	0.566566053608766	0.430940425817534	71.015137129034
a2717	TP53_mut	256	JW-7-24-1	LCK	22	10	2.32630161961136	NA	2.14464532248413	1.48768175047809	0.656963572006042	1.3835175836806	1.14281696162079	0.499235817466361	0.474850178816164	0.574863336884948	0.203481771311888	NA	NA	0.83551882980677	0.173672887639383	71.015137129034
a2718	loss_cnaOV58	293	MP470	PDGFR	5	27	2.99573227355399	NA	4.91435166413667	3.88903736891354	1.02531429522313	1.16087440745681	1.81209729497106	0.589460266147892	0.883225858574436	0.565816359898879	0.203525933351127	NA	NA	0.614514133073005	0.138979321590142	71.015137129034
a2719	loss_cnaOV1	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.7113799388785	2.93963019485564	0.77174974402286	1.42377754208272	1.03549860509193	0.724107948940241	0.542043768223744	0.745292886178583	0.20363562674531	NA	NA	0.424491127877298	0.448637885657419	71.015137129034
a2720	gain_cnaOV19	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.79063897223283	2.90609701174719	0.884541960485639	0.536345826282848	1.00321453428501	0.902750366317906	1.64920079012448	0.881707680915977	0.203636377762906	NA	NA	0.0814249253966533	0.0765545727305926	71.015137129034
a2721	loss_cnaOV87, loss_cnaOV88	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	4.35445185942277	2.40441958474792	1.95003227467485	2.03923644147511	2.29543708363564	0.855557558768878	0.956256094199782	0.849525473199328	0.203803236434717	NA	NA	0.375642447305911	0.232515664402728	71.015137129034
a2722	loss_cnaOV58	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.63416601514194	2.67430522525581	0.959860789886128	1.80091822774132	1.4883994596053	0.626414129521993	0.532984105052881	0.644894610577638	0.203879831787059	NA	NA	0.968142824412625	0.311387248297484	71.015137129034
a2723	loss_cnaOV59	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.38946248889197	2.19969429187736	1.1897681970146	2.33785486898317	1.39672838829282	0.786052105707925	0.508914480877114	0.85182502696091	0.203988076881007	NA	NA	0.232438808080498	0.387515650863087	71.015137129034
a2724	loss_cnaOV36	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.61007557612162	5.09406294274664	0.516012633374982	0.871894082624033	0.542998354869116	0.903936009671003	0.591829493580231	0.950302388115635	0.204077382350057	NA	NA	0.0103056288950035	0.413770714878358	71.015137129034
a2725	SMARCA4_mut	1262	UNC1215	LMBL3	3	30	0	NA	2.37677339574295	2.82077663541918	-0.444003239676238	0.329092469098146	0.489852100638516	0.922883587384393	1.34917471947321	0.906402644997307	0.204169640702093	NA	NA	0.102619492788327	0.125633608479583	71.015137129034
a2726	loss_cnaOV44	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	5.12059384850137	3.49378155744747	1.6268122910539	0.865227744807681	2.04100441336459	0.819795351785936	1.88021281196374	0.797064563114835	0.204205077276815	NA	NA	0.742012816543874	0.0500110880595003	71.015137129034
a2727	gain_cnaOV26	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	4.20068371098297	2.88664872481746	1.31403498616551	0.976517452820359	1.62241982484767	0.827709148638786	1.34563389765369	0.809922910236185	0.204258268334479	NA	NA	0.656491899212024	0.124079335541784	71.015137129034
a2728	gain_cnaOV49	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	3.92611778642996	4.59652511322753	-0.670407326797569	0.968699956360445	1.0080839815736	0.666736029351207	0.692069120469864	0.665031226615737	0.204272451874007	NA	NA	0.181982212069228	0.353807704075186	71.015137129034
a2729	gain_cnaOV94	196	Phenformin	AAPK1 (AMPK) agonist	6	25	8.29404964010203	NA	9.54248386850142	8.56911453949517	0.973369329006255	1.54848827653565	1.70254214928879	0.580426059390762	0.628593282723409	0.571715260860274	0.204322863007771	NA	NA	0.920003255266036	0.211473351629872	71.015137129034
a2730	loss_cnaOV52, loss_cnaOV53	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	2.89609919701682	2.28448683156642	0.611612365450398	0.533162044031231	0.881997224738514	0.751838472274831	1.14714160975527	0.69344023801404	0.204326878542763	NA	NA	0.607720479938809	0.0929359313333229	71.015137129034
a2731	RB1_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	1.72916249712335	2.92879629638341	-1.19963379926007	1.56822963931896	1.52961946278485	0.782979331444143	0.764960544796894	0.784269439848778	0.204668622623644	NA	NA	0.968145855372959	0.314555335300518	71.1078656723966
a2732	gain_cnaOV94	260	NG-25	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	2.5012581070772	3.15498434871635	-0.65372624163915	0.595505612707562	1.14075809193154	0.619934419963267	1.09776671737295	0.573062988781657	0.204999530483962	NA	NA	0.424569157991124	0.0551446267551886	71.1573154425956
a2733	loss_cnaOV39	1129	PF-4708671	RPS6KB1 (p70S6KA)	10	22	2.30258509299405	NA	4.62313085075676	4.00334933356915	0.619781517187605	1.19868335747785	0.797257170892131	0.662201376256915	0.517051908096636	0.77739221397541	0.205049553162645	NA	NA	0.0437128614798593	0.160018791231931	71.1573154425956
a2734	loss_cnaOV84	1378	Bleomycin (50 uM)	DNA damage	6	26	3.91202300542815	NA	3.13679653940324	1.78923519543989	1.34756134396335	3.30719223761537	1.50940000721633	0.698537777822989	0.407463868787683	0.892779473645661	0.205332281256034	NA	NA	0.124448464891422	0.37057848791123	71.1573154425956
a2735	loss_cnaOV54	1375	Temozolomide	DNA akylating agent	11	22	3.40119738166216	NA	6.16624550253029	5.83771090758249	0.328534594947809	0.539327288882274	0.75123121247704	0.476121702191793	0.609156261365299	0.437328201346333	0.205614659237056	NA	NA	0.906768011709098	0.161614937100197	71.1573154425956
a2736	ARID1A_mut	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	2.18370435005274	2.89656790921901	-0.712863559166271	1.23847920739707	1.32983993557712	0.54462085513271	0.575595904160966	0.536052151913235	0.205742331369553	NA	NA	0.938728001448238	0.311969501268756	71.1573154425956
a2737	loss_cnaOV81_(RB1)	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.82614845414408	4.34957892646835	0.476569527675729	0.613710962905828	0.616336194096235	0.773558684156957	0.776537419861697	0.773229825281553	0.205765026010669	NA	NA	0.260969375367495	0.221581906844073	71.1573154425956
a2738	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.52750132804843	5.72165360299419	0.80584772505424	0.42207122380742	1.32881909706441	0.635689791242518	1.90926952514045	0.606439000488853	0.205791142442088	NA	NA	0.5625772083675	0.0273494445967458	71.1573154425956
a2739	loss_cnaOV87, loss_cnaOV88	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.81010915992873	1.56707365592849	1.24303550400025	0.721030677254726	1.48723549526849	0.857965892906227	1.72397034302759	0.835802741364671	0.205908088882458	NA	NA	0.316104281996344	0.0662219059727102	71.1573154425956
a2740	RB1_mut	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	3.29688411168515	4.40899123860418	-1.11210712691903	0.859894917852603	1.30268819314766	0.869678794283763	1.29330584915686	0.853701701427007	0.205996930055351	NA	NA	0.3611760791357	0.136251437360237	71.1573154425956
a2741	loss_cnaOV41	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.97200524490503	3.39425073444742	0.577754510457615	1.3408556683333	0.798223636188154	0.651290097278222	0.43088493721011	0.723800303905596	0.206062832195335	NA	NA	0.789960813003703	0.397291516480352	71.1573154425956
a2742	loss_cnaOV84	1114	Cetuximab	EGFR	5	27	4.18661983833127	NA	6.4314478533212	5.70959507146019	0.721852781861005	0.649160416779431	1.33875541203457	0.568990673850246	1.11197904740127	0.539196910333284	0.206232752907435	NA	NA	0.562598422274001	0.08830912648514	71.1573154425956
a2743	loss_cnaOV21, loss_cnaOV22	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	1.6363303256184	2.57668337345087	-0.940353047832469	1.17464996904108	1.60241811369877	0.60089834145627	0.800538945742386	0.586833760673052	0.206284188312437	NA	NA	0.212671568065754	0.302396956362183	71.1573154425956
a2744	NF1_mut	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	2.55536051794211	1.26694280749178	1.28841771045033	2.26568856230147	1.67959113252445	0.736511496443796	0.56866496653078	0.767101996135108	0.206327133663897	NA	NA	0.606663341545857	0.343488339372982	71.1573154425956
a2745	loss_cnaOV33_(ZFHX3)	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.07327750709398	3.76833387499237	-0.695056367898396	0.881069516233485	1.05046941032327	0.671696050039337	0.788878011430604	0.661662644402468	0.206422596923255	NA	NA	0.827343768927269	0.218575034899135	71.1573154425956
a2746	gain_cnaOV95_(MECOM)	1038	NU-7441	PRKDC (DNAPK)	8	25	0.693147180559945	NA	2.95367726553165	2.40372214304659	0.549955122485052	1.14545718176564	0.973613379653198	0.54184736761004	0.480118446363343	0.564859865299865	0.20643870673175	NA	NA	0.385339958724136	0.247888169801025	71.1573154425956
a2747	PIK3R1_mut	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	1.71468258152489	2.18685314978592	-0.472170568261034	0.617041295132246	0.522776510656779	0.881125182732585	0.765217128879255	0.903197750158729	0.206541610458017	NA	NA	0.0384269282326904	0.167203553004808	71.1573154425956
a2748	loss_cnaOV1	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	3.91115225551068	2.71059732054468	1.200554934966	0.959020819926381	1.56387617617825	0.783613005419263	1.25185492329369	0.76767902296451	0.206575512321405	NA	NA	0.968153124933996	0.14410264806408	71.1573154425956
a2749	loss_cnaOV85	253	XMD14-99	EPHB3, CAMK1	7	25	2.32630161961136	NA	5.18570163008884	4.76888531494043	0.41681631514841	0.487460087029785	0.624567672775893	0.695088539969185	0.855077833527203	0.667367738224216	0.206617453140558	NA	NA	0.0451774601701861	0.0854049962888022	71.1573154425956
a2750	loss_cnaOV35	1018	ABT-888	PARP1, PARP2	5	26	1.6094379124341	NA	3.97302579253724	4.36238468023265	-0.389358887695412	1.18189558988838	0.713144308806569	0.490118677714694	0.329435942587944	0.545974893001664	0.206635196177798	NA	NA	0.215039918086604	0.511021686859721	71.1573154425956
a2751	loss_cnaOV56	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	5.20909538585675	4.36533023614433	0.843765149712425	1.34406157851519	0.9570355674457	0.855227548613394	0.627772687799429	0.881644505610601	0.206680441201655	NA	NA	0.365067076388098	0.39091384886573	71.1573154425956
a2752	loss_cnaOV43_(NF1)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	4.68543892984716	3.9118104490068	0.77362848084036	1.41181828658856	1.49230014199108	0.52207929255738	0.547966043639874	0.518413460584515	0.20670043508745	NA	NA	0.3194540025804	0.308861580364301	71.1573154425956
a2753	gain_cnaOV18_(CCNE1)	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-1.87459870776464	-3.46953690149629	1.59493819373165	1.61717956427946	1.78340441545729	0.899853945849473	0.986246814491676	0.894322218733931	0.206754592126737	NA	NA	0.131053661526037	0.222018800108068	71.1573154425956
a2754	gain_cnaOV19	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-1.87459870776464	-3.46953690149629	1.59493819373165	1.61717956427946	1.78340441545729	0.899853945849473	0.986246814491676	0.894322218733931	0.206754592126737	NA	NA	0.131053661526037	0.222018800108068	71.1573154425956
a2755	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	310	YM201636	FYV1	3	29	1.63315443905142	NA	1.722718265831	2.42252329285951	-0.69980502702851	0.835743484315204	0.850018102292872	0.824197993265599	0.837344281064806	0.823282498503066	0.206887551741426	NA	NA	0.643483397401277	0.2804733705332	71.1573154425956
a2756	SMAD4_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.45812926891456	3.7629103112678	0.695218957646754	1.01854324806226	0.840731563018328	0.809097123626293	0.682562040413485	0.82692144345198	0.206948100706282	NA	NA	0.937937446790924	0.359078463097484	71.1573154425956
a2757	TP53_mut	257	NPK76-II-72-1	PLK3	22	10	2.32630161961136	NA	3.03798870980162	3.65146302048604	-0.613474310684424	1.34630176579479	0.786195266498583	0.508726299878527	0.455673702784056	0.78030781515209	0.20701145526811	NA	NA	0.593046741465456	0.117484998160964	71.1573154425956
a2758	PIK3R1_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	-1.45771451580893	0.0348058868888568	-1.49252040269779	1.76412682875227	1.50907918270706	0.97079122425454	0.846039172678656	0.989027229187824	0.207083172715775	NA	NA	0.0934631602591521	0.189399374955039	71.1573154425956
a2759	gain_cnaOV49	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	0.67698876009002	1.65718196556138	-0.980193205471361	0.365430652023498	1.6613747270239	0.609644386508151	2.68229608010095	0.589989235738061	0.207092923737986	NA	NA	0.0728405411990088	0.0193378306635079	71.1573154425956
a2760	loss_cnaOV38	1028	VX-702	p38	8	23	0.693147180559945	NA	3.72311753581263	3.18917850365946	0.533939032153171	0.886243313255274	0.906650910548746	0.59210294809312	0.602474539629474	0.588913578468704	0.207358482864813	NA	NA	0.50875355465919	0.169223751054211	71.1573154425956
a2761	PIK3CA_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	6	25	2.32630161961136	NA	1.91890109863816	2.38380817494612	-0.464907076307967	1.60154571757272	1.36714211145846	0.329642139363309	0.290286484617232	0.340057608065344	0.207363623397486	NA	NA	0.520745156415036	0.533205574443918	71.1573154425956
a2762	gain_cnaOV96	186	Bexarotene	Retinioic acid X family agonist	4	14	2.07944154167984	NA	4.35379783414588	3.61566588463958	0.738131949506291	1.34141550740968	0.818558500604904	0.786051116880799	0.550263468275875	0.901746117059222	0.20747744868021	NA	NA	0.799790123678392	0.359504224540934	71.1573154425956
a2763	PIK3CA_mut	1066	AZD6482	PI3Kbeta	7	26	1.6094379124341	NA	1.52208362975434	2.60985249643012	-1.08776886667579	0.833823411072473	1.31339496034556	0.880647137605245	1.30455543971437	0.828211542999671	0.207513972066176	NA	NA	0.103068814645924	0.0173323685967384	71.1573154425956
a2764	loss_cnaOV40	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	2.57354518705536	3.01942097334619	-0.445875786290828	0.503598166455223	0.901865997928818	0.53037510127551	0.885380082753881	0.494392501008802	0.20757082346209	NA	NA	0.315072839798678	0.175408531518902	71.1573154425956
a2765	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	4.44420416486348	3.76692309569982	0.677281069163659	1.12173956524976	1.21513301162065	0.566095155223985	0.603777463276745	0.557371960671494	0.207769639094171	NA	NA	0.692330987974635	0.196641263372298	71.1573154425956
a2766	loss_cnaOV34	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	3.80850934964599	4.37526077906391	-0.566751429417914	0.83507719214845	0.79120740828836	0.710747512274366	0.678681485671763	0.716312086414841	0.207804977560587	NA	NA	0.306292265281813	0.215157953980842	71.1573154425956
a2767	gain_cnaOV26	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.21163032112933	2.19549000007479	1.01614032105454	1.81469538431841	1.35187584985866	0.731691500242259	0.559950904066581	0.75165209968118	0.207805034664289	NA	NA	0.520768359795393	0.436082832946887	71.1573154425956
a2768	gain_cnaOV4_(KRAS)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	NA	1.73290603434246	1.07690834815892	0.655997686183546	1.32523171753226	1.19049811698383	0.538701137065138	0.495006026119788	0.551027907415375	0.207859026482695	NA	NA	0.257255537984812	0.266296438428355	71.1573154425956
a2769	loss_cnaOV85	329	QL-XI-92	DDR1	7	25	2.32630161961136	NA	5.03888817379603	4.39221457705264	0.646673596743391	0.768821005599361	1.03520831435292	0.654729802359795	0.84112373625803	0.624679678261289	0.207897600331001	NA	NA	0.182172135333906	0.0934097240050032	71.1573154425956
a2770	gain_cnaOV96	262	VX-11e	ERK	5	27	1.63315443905142	NA	3.36930747317844	2.76482760843082	0.604479864747629	1.22631536385527	1.08701704386561	0.546247807477692	0.492923665937997	0.556090512249928	0.208166171777915	NA	NA	0.380720879331606	0.34832611767372	71.1573154425956
a2771	gain_cnaOV18_(CCNE1)	281	CH5424802	ALK	4	28	1.63315443905142	NA	4.36392150825206	3.86527481933342	0.498646688918636	0.245975823273594	0.749888549577115	0.696777898351227	2.02721829439311	0.664961065480781	0.208259091594359	NA	NA	0.95483201099213	0.0191327397690315	71.1573154425956
a2772	gain_cnaOV96	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.50811665786838	2.06113222310885	0.44698443475953	0.342937255387108	0.560377168558748	0.822944809041084	1.3034000469123	0.797649261673426	0.208266928510153	NA	NA	0.0384638339946438	0.0711218356372679	71.1573154425956
a2773	loss_cnaOV54	224	AS605240	PI3Kgamma	10	22	2.99573227355399	2.32630161961136	2.77914000103478	3.64599246721673	-0.866852466181948	1.90179833276729	1.49942647927021	0.531616587305304	0.455806723166383	0.578122687685133	0.208385493065554	NA	NA	0.622402706635148	0.223390723490357	71.1573154425956
a2774	loss_cnaOV20	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.40927990498519	3.9003203828845	0.508959522100688	0.860006314366849	0.724168312533554	0.684347594965299	0.591809052559565	0.702819376782806	0.208401026355931	NA	NA	0.516720029620547	0.267505198818633	71.1573154425956
a2775	loss_cnaOV35	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	2.32202993440655	0.962492220576665	1.35953771382989	2.46758380429592	1.33630340975082	0.898021029557421	0.550959084535655	1.01738699752581	0.208609703444888	NA	NA	0.518423830183231	0.442277849992748	71.1573154425956
a2776	loss_cnaOV43_(NF1)	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.83368593633756	4.31960796254635	0.514077973791204	1.16954766537762	0.78739721757095	0.607328530711932	0.439552819444275	0.65288263956163	0.208748777168155	NA	NA	0.866825417504573	0.39078384681573	71.1573154425956
a2777	gain_cnaOV96	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.68121243286314	2.98325575585331	0.697956677009832	0.918656314518221	0.893375010610116	0.779097526428784	0.759758209876201	0.781258339130365	0.208774436896456	NA	NA	0.229445003368422	0.229240235866711	71.1573154425956
a2778	NF1_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	1.95077936119735	0.868948946402816	1.08183041479453	1.13517629328686	1.5544173317516	0.712802761985827	0.953006525235067	0.69597166262645	0.20880999352834	NA	NA	0.786606824422296	0.153922256988713	71.1573154425956
a2779	loss_cnaOV52, loss_cnaOV53	1378	Bleomycin (50 uM)	DNA damage	9	23	3.91202300542815	NA	2.91624660442599	1.69976847295751	1.21647813146848	1.70236993281825	1.99704717430392	0.632631056187494	0.714579192229164	0.609138405502359	0.208818701003707	NA	NA	0.124603437241952	0.101913466043111	71.1573154425956
a2780	loss_cnaOV40	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	8	25	-1.38629436111989	0.693147180559945	-1.5196866979574	-2.54739631904306	1.02770962108566	1.45431055513333	1.59467339042722	0.657069737127012	0.706664486108639	0.644464018309313	0.208880509648718	NA	NA	0.116974441650113	0.113442418133271	71.1573154425956
a2781	loss_cnaOV34	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.62537269759718	2.67587546053166	0.949497237065511	1.23066082830328	1.57307270909272	0.619293754712785	0.77153445955909	0.603593992558132	0.208913281605832	NA	NA	0.968161927497686	0.17544135532859	71.1573154425956
a2782	loss_cnaOV57_(ZNRF3)	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	3.52604771764403	2.81664796149842	0.709399756145606	1.44593953306331	1.20866912535034	0.574668634322965	0.490615091381242	0.586926348383379	0.209097973486026	NA	NA	0.221941237717306	0.407497747195111	71.1573154425956
a2783	RB1_mut	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.78259163378465	4.17399774619291	0.608593887591739	0.590916081683915	0.990440822507262	0.627645792826066	1.02991593299923	0.61446769333589	0.209104269814372	NA	NA	0.200499449221514	0.20577602655802	71.1573154425956
a2784	gain_cnaOV18_(CCNE1)	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	5.09992339420998	4.35129309189863	0.748630302311353	0.642033433467242	1.01611258091986	0.759157698018207	1.16603009015971	0.736759209923019	0.209180439473056	NA	NA	0.365206813694678	0.0967392285128646	71.1573154425956
a2785	loss_cnaOV41	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	1.90666955471903	0.471978606884897	1.43469094783413	2.09347521551104	2.29225468299728	0.632926346903003	0.685315468367706	0.625886363533641	0.209201857885956	NA	NA	0.94467403888712	0.215561275377238	71.1573154425956
a2786	gain_cnaOV72_(ASXL1)	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.77315250978714	2.20183799499181	0.571314514795326	0.51469042066293	0.927264075071504	0.647816432041783	1.11001583060253	0.616129245329892	0.20929184073171	NA	NA	0.586237182769947	0.080264355735953	71.1573154425956
a2787	loss_cnaOV83	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	2.87815960450648	1.34367127871835	1.53448832578813	3.13732897245457	2.02055100522654	0.679540586099859	0.489106606052723	0.759440529746038	0.209337501611321	NA	NA	0.599342723446457	0.409910987864302	71.1573154425956
a2788	gain_cnaOV94	290	KIN001-260	IKK	7	24	2.99573227355399	NA	5.25262499271338	4.73288600450389	0.519738988209484	0.815172133875114	0.897818541416712	0.589704236617251	0.637581888059374	0.578890905270638	0.209393207796578	NA	NA	0.658386172027632	0.175920271116178	71.1573154425956
a2789	BRCA1_mut	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.73849213094817	4.15909444011547	0.579397690832701	0.264435600863326	1.01360223081702	0.599284802076762	2.19107294532616	0.571622351665184	0.209411774157367	NA	NA	0.200515245058626	0.020846298548241	71.1573154425956
a2790	loss_cnaOV102	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	5.10153679250503	4.44846422605514	0.653072566449889	1.28364254029166	0.873815766974848	0.719213162431968	0.508765131998119	0.747380158532533	0.209485552738228	NA	NA	0.519337092894025	0.473064146436899	71.1573154425956
a2791	loss_cnaOV55	290	KIN001-260	IKK	7	24	2.99573227355399	NA	5.25253432799206	4.73291244838094	0.519621879611118	0.90300491616637	0.875635994331047	0.589562731550669	0.575436379479669	0.593422247343875	0.209506686850242	NA	NA	0.658390719128872	0.20852602390963	71.1573154425956
a2792	loss_cnaOV34	272	AR-42	HDAC	5	25	1.63315443905142	NA	-0.740135269737852	0.502144383856717	-1.24227965359457	0.947306825505598	1.90189511839575	0.691366307482654	1.31138045261263	0.653179894926293	0.209695850420039	NA	NA	0.476124915868564	0.0501396065265883	71.1573154425956
a2793	gain_cnaOV19	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	3.57736344323827	1.88306220648765	1.69430123675062	0.551335681284042	2.0007578009978	0.874184514448385	3.07308468192128	0.846829754158978	0.209831900662219	NA	NA	0.124647918188731	0.00622372107437513	71.1573154425956
a2794	NF1_mut	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.09457890823466	5.92635680582473	-0.831777897590066	1.05696314947193	1.28682527170253	0.657158445177844	0.786950706848795	0.646379827845301	0.209852232207594	NA	NA	0.562770267528728	0.220005654840078	71.1573154425956
a2795	loss_cnaOV55	1061	SB590885	BRAF	8	25	1.6094379124341	NA	3.38529115976531	4.1010593968933	-0.715768237127996	1.70815967732931	1.08730974796354	0.570492704190733	0.419028880395475	0.658292853962346	0.209903885967339	NA	NA	0.565262437783432	0.294043368867528	71.1573154425956
a2796	loss_cnaOV82	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	3.03503311854077	1.10936111777241	1.92567200076836	1.77412807056822	2.30527360003916	0.846923012665348	1.08541882218886	0.835333385475654	0.209933058305656	NA	NA	0.353422520361698	0.189347128495826	71.1573154425956
a2797	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1377	Afatinib (rescreen)	ERBB2, EGFR	8	25	2.30258509299405	NA	3.31141385343727	2.44509265342775	0.866321200009522	1.57678479522341	1.70082382427267	0.517633537963626	0.54942259884411	0.50935387172154	0.210052728048125	NA	NA	0.633155768384877	0.20807167551763	71.1573154425956
a2798	gain_cnaOV18_(CCNE1)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.37751197018292	2.20134263928551	1.17616933089741	1.37366075842293	1.52915437169096	0.776449668559607	0.856229839635038	0.769163239939461	0.210158309760864	NA	NA	0.232773038676748	0.186959449680666	71.1573154425956
a2799	loss_cnaOV83	163	JQ1	BRD4	4	15	0.940007258491471	NA	1.05098207223314	-0.168147816209871	1.21912988844301	2.03366194482098	1.76463224264644	0.671693939434394	0.599475193774318	0.690869099509747	0.21020988609149	NA	NA	0.567151426152209	0.331507535351216	71.1573154425956
a2800	loss_cnaOV56	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.53222350259722	4.67314376028178	0.859079742315435	0.332145680199724	1.25103809996475	0.709821595251911	2.58645465989158	0.686693508646654	0.210264293307288	NA	NA	0.414781526638033	0.0168170339351717	71.1573154425956
a2801	loss_cnaOV43_(NF1)	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	4.46636731551384	3.36113659602628	1.10523071948756	1.3352398052279	1.71909989586892	0.661259179468562	0.827739493056018	0.64291244630023	0.210280873363552	NA	NA	0.692196819057921	0.152020492775058	71.1573154425956
a2802	gain_cnaOV26	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.79980893756599	1.56813919617291	1.23166974139308	1.77806592291621	1.42334549791735	0.849605333556385	0.692701955264411	0.865334343063764	0.210621987517097	NA	NA	0.31637800214165	0.352696840861704	71.1573154425956
a2803	loss_cnaOV44	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.77204887944588	3.40733005128267	1.36471882816321	0.613451780843561	1.72495124340947	0.816128580129634	2.22465541837139	0.791163711657008	0.210635499260806	NA	NA	0.692209726336536	0.0273785034940369	71.1573154425956
a2804	loss_cnaOV20	1030	KU-55933	ATM	5	28	2.30258509299405	NA	4.72907507449182	4.04776611445907	0.681308960032748	0.931857740531635	1.01785226107007	0.676459516570496	0.731129796318539	0.669359381602679	0.210645468045591	NA	NA	0.52128484248499	0.189514502272035	71.1573154425956
a2805	loss_cnaOV58	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.56936916850214	4.86854411313896	0.700825055363183	0.948788999549707	0.779974957281529	0.878674624574099	0.738652172080191	0.898522508730011	0.210653679186448	NA	NA	0.440241606456072	0.328108245254239	71.1573154425956
a2806	loss_cnaOV59	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.56936916850214	4.86854411313896	0.700825055363183	0.948788999549707	0.779974957281529	0.878674624574099	0.738652172080191	0.898522508730011	0.210653679186448	NA	NA	0.440241606456072	0.328108245254239	71.1573154425956
a2807	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.56936916850214	4.86854411313896	0.700825055363183	0.948788999549707	0.779974957281529	0.878674624574099	0.738652172080191	0.898522508730011	0.210653679186448	NA	NA	0.440241606456072	0.328108245254239	71.1573154425956
a2808	loss_cnaOV33_(ZFHX3)	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	-0.914323250126912	0.271021780234223	-1.18534503036114	0.917230553383891	1.64422663553836	0.748057536251202	1.29230870688738	0.720913409831136	0.210729387449173	NA	NA	0.452117702829664	0.0748266812045293	71.1573154425956
a2809	loss_cnaOV85	205	BMS-708163	g-secretase	7	25	2.32630161961136	0.940007258491471	5.37517615940453	4.97431654312864	0.400859616275892	0.509612775977839	0.618946349256223	0.669573390753729	0.786596481037446	0.647648405645495	0.210799280248106	NA	NA	0.103491150154663	0.10661020278055	71.1573154425956
a2810	loss_cnaOV20	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.61294826187668	2.97051876220768	0.642429499669001	0.899375838548896	0.894532331943363	0.717671008689844	0.714305935442443	0.718173593874834	0.21080086590742	NA	NA	0.229552738174749	0.195567025955089	71.1573154425956
a2811	loss_cnaOV35	272	AR-42	HDAC	5	25	1.63315443905142	NA	-0.737905540135235	0.501698437936193	-1.23960397807143	0.949706709643917	1.90199873148079	0.689771661158407	1.30524925799061	0.651737541962683	0.210810541619404	NA	NA	0.476188145212241	0.050917536841924	71.1573154425956
a2812	loss_cnaOV102	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	2.31563178681287	0.528616372380991	1.78701541443188	0.905855698249772	2.33380526808847	0.788353523394654	1.97273739943859	0.765708878485633	0.210974236003784	NA	NA	0.944685867911313	0.0423377505203104	71.1596522443059
a2813	loss_cnaOV44	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	4.12849631077194	3.41711859522457	0.71137771554737	1.56595221116883	0.820564835318361	0.80133017968059	0.454278049147103	0.866936633071013	0.211189699702779	NA	NA	0.790084437220017	0.51509192807369	71.1596522443059
a2814	loss_cnaOV43_(NF1)	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.6466094351334	3.89628171394274	0.75032772119066	0.727092024449167	1.05870366877216	0.735087565452853	1.03195702326552	0.708723076459022	0.211285127842726	NA	NA	0.0978266633182577	0.0882881450194391	71.1596522443059
a2815	gain_cnaOV48_(SOX17)	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	2.65621291579942	3.487886600123	-0.831673684323576	0.507593281956069	1.24063603757229	0.68977776864289	1.63846471946718	0.670360733637091	0.211563305390937	NA	NA	0.316745423352379	0.0750474452923687	71.1596522443059
a2816	loss_cnaOV36	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.3151674583074	4.75968914441143	0.55547831389597	0.390164475259143	0.753222325471887	0.756141667961127	1.42370294867832	0.737469263869692	0.211663653688913	NA	NA	0.760380772484522	0.107913085951281	71.1596522443059
a2817	loss_cnaOV44	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-2.36180668034883	-3.83359946583033	1.4717927854815	2.86951966519664	1.56139710176665	0.873702568252804	0.512905627841598	0.942612730493883	0.211687367438978	NA	NA	0.235193533354574	0.469168816515755	71.1596522443059
a2818	loss_cnaOV59	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	3.52202691041261	2.81722236253148	0.704804547881125	1.45004306170104	1.20847136686781	0.57080418272773	0.48605766718012	0.583219898463858	0.211716840787494	NA	NA	0.222083533416473	0.411384620554182	71.1596522443059
a2819	loss_cnaOV39	345	KIN001-270	CDK9	9	23	2.99573227355399	NA	4.97607719916647	5.2748210646592	-0.298743865492734	0.853379531782572	0.730552545744636	0.390394161255504	0.35007151491987	0.408928648914954	0.211752750551784	NA	NA	0.323616181409502	0.371584707249764	71.1596522443059
a2820	NF1_mut	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.74315679518002	3.2094814877224	0.533675307457613	1.11162292336803	1.02492029483951	0.516168027306419	0.480086633910594	0.520699326713186	0.211805795973127	NA	NA	0.0855573613950421	0.41879808103343	71.1596522443059
a2821	NF1_mut	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.91492955846051	4.32612877238426	0.588800786076251	0.818792973265385	0.847316475644587	0.697137123665753	0.719108254835268	0.694900669349463	0.212016559388164	NA	NA	0.866875637323359	0.251527511295901	71.1596522443059
a2822	gain_cnaOV49	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.97773614718853	-4.10127660288437	-0.876459544304156	0.555491664307282	1.36281285182411	0.66178279084402	1.57780863444123	0.643125388149243	0.21207336318656	NA	NA	0.208389956356223	0.0834077161195948	71.1596522443059
a2823	loss_cnaOV41	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.40617726245524	3.90089494631597	0.505282316139271	0.919648107863031	0.713228855006316	0.679081336443548	0.549430061149569	0.708443457653991	0.212128973138475	NA	NA	0.516907330428962	0.297123487261428	71.1596522443059
a2824	gain_cnaOV49	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	2.93101812563321	4.00668120384108	-1.07566307820787	1.92886420087349	1.67961756584038	0.633494981340969	0.557666567569013	0.640421426927425	0.212205356976335	NA	NA	0.138927059422064	0.438589537929192	71.1596522443059
a2825	loss_cnaOV44	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.53850485599304	5.01271145262305	0.525793403369982	0.586987191399607	0.603280790005704	0.873108911837695	0.895749363995975	0.871556681533006	0.212291296646781	NA	NA	0.103550108793594	0.2559442250311	71.1596522443059
a2826	gain_cnaOV26	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.27940694378201	4.03529572164287	1.24411122213914	0.76945888471139	1.45691599992579	0.875230468079281	1.61686510723153	0.853934765080835	0.212575548217578	NA	NA	0.0871542352586927	0.0798313415433816	71.1596522443059
a2827	gain_cnaOV19	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.56006721086568	2.07083664896777	0.489230561897902	0.15575085988884	0.561601156456552	0.898294292745147	3.14110986126862	0.871135246559542	0.21260971063098	NA	NA	0.0385552531432226	0.00539504068333691	71.1596522443059
a2828	loss_cnaOV40	1031	Elesclomol	HSP70	7	24	-1.6094379124341	NA	-4.70737611161623	-3.87088866789606	-0.836487443720169	1.76739024280651	1.41449168740242	0.559763601037232	0.473289612820243	0.591369642656792	0.212683687476593	NA	NA	0.861141487961042	0.282142318276544	71.1596522443059
a2829	ARID1A_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	9	24	1.6094379124341	NA	1.5852326531695	2.62841210589525	-1.04317945272575	0.981187185596159	1.63083901482845	0.699864469941363	1.06318087724711	0.639658141141223	0.212816505528209	NA	NA	0.23291350147954	0.0349017676307631	71.1596522443059
a2830	ARID1A_mut	163	JQ1	BRD4	5	14	0.940007258491471	NA	-0.423798841047559	0.271478946501593	-0.695277787549152	2.37816766370434	1.67083843844236	0.373482678510914	0.292358607915034	0.41612508519814	0.212897762570512	NA	NA	0.567378438961762	0.570739450366867	71.1596522443059
a2831	loss_cnaOV59	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.1330701093924	2.56478366152486	-0.431713552132455	0.673715341447512	0.610636199869618	0.699432243092281	0.640795192825647	0.706989779224739	0.213033871023308	NA	NA	0.855149061991396	0.296338888287267	71.1596522443059
a2832	loss_cnaOV40	261	TL-1-85	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.13449530180683	3.67350762212856	-0.539012320321728	1.18469917090618	0.868152992148275	0.573399802323959	0.45497822025944	0.620872501962958	0.213227144336362	NA	NA	0.72299928045019	0.294688590841798	71.1596522443059
a2833	loss_cnaOV82	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.23435118128842	2.92887934402022	-0.694528162731803	0.357121930663641	0.804299167935952	0.887599969021627	1.94479280911469	0.863519683246906	0.213262209087074	NA	NA	0.0172785639569005	0.0456298370478416	71.1596522443059
a2834	gain_cnaOV18_(CCNE1)	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	5.15516252168538	4.19102549677377	0.964137024911613	0.858835237084589	1.31725419977721	0.753181370304581	1.12260999931079	0.731929361147365	0.213387508233047	NA	NA	0.361585582785823	0.106288584974369	71.1596522443059
a2835	loss_cnaOV35	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	2.46465694324642	3.54370183603273	-1.07904489278631	1.53068882926849	1.64839580318677	0.660696996870689	0.704940724825162	0.654603033264367	0.213438298502868	NA	NA	0.622613320043291	0.203739088829257	71.1596522443059
a2836	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.49847474179123	2.78938555422628	0.709089187564952	1.85985239104316	0.978132220791207	0.66896302080137	0.381261002744006	0.724942060482756	0.213630525624322	NA	NA	0.296949591916263	0.578566526468436	71.1596522443059
a2837	loss_cnaOV85	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	6	13	0.940007258491471	NA	2.7404119957073	2.24142996729239	0.498982028414901	0.860992702030886	1.0093476248183	0.515436441023935	0.579542692101706	0.494360927935733	0.213666507798763	NA	NA	0.39251549482114	0.289608805085687	71.1596522443059
a2838	loss_cnaOV34	1018	ABT-888	PARP1, PARP2	5	26	1.6094379124341	NA	3.97908254324498	4.36121992048117	-0.382137377236184	1.18115895570004	0.713994306963073	0.480721615205159	0.323527477306984	0.535210678165741	0.213718518295077	NA	NA	0.215435639344468	0.518290891599384	71.1596522443059
a2839	PIK3CA_mut	231	FMK	RSK	6	14	2.99573227355399	2.32630161961136	4.75784693841139	5.45071617671548	-0.692869238304088	0.701125657407025	0.66334362295544	1.02791797568992	0.98822405225695	1.04451028746926	0.213853216085064	NA	NA	0.114078947413275	0.0695151421583001	71.1596522443059
a2840	loss_cnaOV56	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.86586742979554	4.40911339795322	0.456754031842327	0.723178317440263	0.528812842102873	0.839720777676667	0.63159254201514	0.863734757321707	0.213960621171897	NA	NA	0.355033307339861	0.388624530118259	71.1596522443059
a2841	PIK3CA_mut	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.92097032907258	4.49532791487347	0.425642414199106	0.692691922545503	0.986025067849846	0.455353445916212	0.614475786919755	0.431675043644959	0.213987786130743	NA	NA	0.94195171777201	0.215609774321199	71.1596522443059
a2842	loss_cnaOV21, loss_cnaOV22	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.19874122798985	2.19687097433973	1.00187025365012	1.62641245662657	1.37056597067151	0.72091334993384	0.616000110899391	0.730990171278841	0.214019184278734	NA	NA	0.521088875328573	0.398992092647503	71.1596522443059
a2843	loss_cnaOV1	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	2.8200126686595	1.39771193656011	1.42230073209939	2.22852132152549	1.85987370796235	0.753859314031053	0.638226216801814	0.764729737299011	0.21414025470868	NA	NA	0.778171409281274	0.384874729106939	71.1596522443059
a2844	gain_cnaOV19	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.27244823311715	3.49011516256663	0.782333070550524	0.398424924714849	0.919424013496558	0.874104869500177	1.96356458148404	0.850894754831692	0.214224195939075	NA	NA	0.135281638208648	0.0441559638244389	71.1596522443059
a2845	loss_cnaOV38	1091	BMS-536924	IGF1R	8	24	1.38629436111989	NA	2.72222369119029	2.28396992628857	0.438253764901719	1.3765233806861	0.742499753285267	0.471270107938137	0.318377276442106	0.590240956933144	0.214225458618466	NA	NA	0.729479484275954	0.413775691101799	71.1596522443059
a2846	loss_cnaOV59	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.84429656172305	2.90197900432464	0.94231755739841	1.09639821652653	1.16426994491778	0.814144147894037	0.859466517907828	0.809363465501946	0.214238285926344	NA	NA	0.0821965974332102	0.185517117925855	71.1596522443059
a2847	loss_cnaOV35	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	3.81422790611911	4.37416105666523	-0.559933150546115	0.83791955088609	0.791540854096787	0.701584309431604	0.668242136078567	0.707396399880136	0.214282654447704	NA	NA	0.306675296548517	0.221242227850167	71.1596522443059
a2848	gain_cnaOV72_(ASXL1)	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.15043050553574	-4.19449032550652	1.04405981997078	1.68945704545437	1.47010806950405	0.698698080757605	0.617985418913085	0.710192564498339	0.214318477696435	NA	NA	0.861169078586059	0.311004876148615	71.1596522443059
a2849	SMAD4_mut	163	JQ1	BRD4	3	16	0.940007258491471	NA	1.24783986025628	-0.128863033436521	1.3767028936928	2.51312504788243	1.69854996518054	0.759152402663926	0.547805169843345	0.810516571142767	0.214334762305938	NA	NA	0.567498379649919	0.445874972706027	71.1596522443059
a2850	gain_cnaOV95_(MECOM)	1028	VX-702	p38	8	23	0.693147180559945	NA	3.69201439783904	3.19999698643288	0.492017411406164	0.695080578565407	0.964262891701186	0.542685219662077	0.707856652277137	0.51025235507936	0.21435238355122	NA	NA	0.509120230495674	0.139581545757606	71.1596522443059
a2851	loss_cnaOV44	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.30625061065527	4.45375275210077	0.852497858554496	1.06888553487881	0.987282201430705	0.858566989080815	0.797557671739989	0.863479415833803	0.214370663427618	NA	NA	0.18250187478125	0.298776494049395	71.1596522443059
a2852	loss_cnaOV20	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	2.46662585384356	3.54333722295919	-1.07671136911563	1.52012385289085	1.6501465708266	0.659180778151294	0.708305028611992	0.652494383317885	0.214523275695749	NA	NA	0.622657761240559	0.20216710543168	71.1596522443059
a2853	gain_cnaOV19	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	5.08936740938961	3.4970118787349	1.59235553065471	0.492884467910648	2.05245941127211	0.801409412351389	3.23068717787913	0.775828024617435	0.214549359450165	NA	NA	0.742324403143725	0.00540277903287682	71.1596522443059
a2854	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.97979653771975	3.46373862362237	0.516057914097381	0.961146042321381	0.879504081146753	0.579305249086397	0.53691935603354	0.586760113067937	0.214786978675858	NA	NA	0.656716998040541	0.311872396872545	71.1596522443059
a2855	loss_cnaOV83	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.01518866488702	2.88491322668126	-0.869724561794241	0.424452594025634	1.77762917522377	0.523260757540921	2.0490499387588	0.489260962812876	0.21488160050722	NA	NA	0.311495122240461	0.0346120160947091	71.1596522443059
a2856	loss_cnaOV16, loss_cnaOV17	1067	CCT007093	PPM1D	6	27	1.88706964903238	NA	4.88421468432353	4.40206429220107	0.482150392122461	0.65154977112364	0.684467549540831	0.709810729942458	0.740005466184052	0.704416728661435	0.214944361872269	NA	NA	0.0758026375951952	0.144603839055287	71.1596522443059
a2857	gain_cnaOV51_(MYC)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	24	2.99573227355399	NA	4.47231984314819	3.88614658446808	0.586173258680111	1.96003293134734	1.30958181313748	0.39419220837051	0.299062964353958	0.44760338972314	0.215032802829311	NA	NA	0.319930934221129	0.449906914882634	71.1596522443059
a2858	RB1_mut	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.410962334258993	-0.858771444324888	0.447809110065896	0.991863747231725	0.785932112272562	0.558481025687698	0.451482485689918	0.569780904830359	0.215154321974819	NA	NA	0.0728479749282864	0.51960327252129	71.1596522443059
a2859	loss_cnaOV83	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.46558395710395	2.05276361843252	0.412820338671439	0.479986356890924	0.551201234884721	0.760906212951486	0.860066818035105	0.748946686880658	0.21519934452938	NA	NA	0.0386087874179854	0.133859009265708	71.1596522443059
a2860	loss_cnaOV36	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.00889201476817589	-0.813542459915718	0.804650445147542	1.49468645459764	0.843706420473959	0.894028450182887	0.538340628345459	0.953709045731242	0.215248619701047	NA	NA	0.0382483204110588	0.450458713515196	71.1596522443059
a2861	gain_cnaOV96	192	LFM-A13	BTK	4	15	2.77258872223978	NA	5.11551815254258	4.62096982613349	0.494548326409093	0.725882271371721	0.653287198570358	0.74181571740224	0.681306522991022	0.757015180293374	0.215257388456256	NA	NA	0.95524705458466	0.278557655221276	71.1596522443059
a2862	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	4.12739256178838	3.55658842382575	0.570804137962638	0.888120070016647	1.06652622392	0.552402425125469	0.64271054920754	0.535199346402059	0.215277385392228	NA	NA	0.827524626033847	0.178183405643076	71.1596522443059
a2863	loss_cnaOV36	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.53590531096982	5.01298037107373	0.522924939896082	0.585855982211103	0.603601333607489	0.868019472693226	0.892582743496943	0.866341591346004	0.215283014930551	NA	NA	0.103666913139324	0.257196598057516	71.1596522443059
a2864	loss_cnaOV16, loss_cnaOV17	1052	RO-3306	CDK1	6	27	1.6094379124341	NA	3.91313543248177	3.38593459978378	0.52720083269799	1.24231469079481	0.802157646682666	0.59367345301376	0.424369796642022	0.657228457371486	0.215300218197455	NA	NA	0.790180964540417	0.358653413334002	71.1596522443059
a2865	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.184602753949404	-1.18811004351538	1.37271279746478	0.553975597279826	2.00902918839427	0.705340643068612	2.47793008248952	0.683271704261267	0.215386549005038	NA	NA	0.434266661903678	0.0192794307177308	71.1596522443059
a2866	gain_cnaOV48_(SOX17)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-3.52879106715364	-1.83590394179543	-1.69288712535821	1.71261082661151	2.00488464628712	0.851841756304586	0.988483255537791	0.844381310662086	0.215512977646408	NA	NA	0.268974545118079	0.221049749613418	71.1596522443059
a2867	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.01200920306233	3.75888882992625	-0.746879626863921	1.03736573612612	0.831013243299571	0.863335214631741	0.719977150636408	0.898757791029184	0.215525735333263	NA	NA	0.0527250342895832	0.250848400676441	71.1596522443059
a2868	loss_cnaOV85	221	TAK-715	p38a	7	25	2.99573227355399	2.32630161961136	4.68523371092647	4.16389807780455	0.521335633121922	0.997673261133515	0.842030989508626	0.59555615708659	0.522551473946091	0.619140672513908	0.215543170104351	NA	NA	0.512997926217807	0.240169838345818	71.1596522443059
a2869	loss_cnaOV16, loss_cnaOV17	1129	PF-4708671	RPS6KB1 (p70S6KA)	6	26	2.30258509299405	NA	4.74108628772747	4.07147985075862	0.669606436968854	1.0332280615404	0.92513446314788	0.709321350592127	0.648072252287227	0.723793636106084	0.215600087631395	NA	NA	0.0439632913306871	0.188284025480105	71.1596522443059
a2870	loss_cnaOV16, loss_cnaOV17	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.35134276657939	3.74880120872538	0.602541557854015	1.17895647619017	0.795682870550876	0.699859221674026	0.511080408838454	0.75726345275833	0.215622500345222	NA	NA	0.938031601118284	0.389854864327907	71.1596522443059
a2871	loss_cnaOV41	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.35134276657939	3.74880120872538	0.602541557854015	1.17895647619017	0.795682870550876	0.699859221674026	0.511080408838454	0.75726345275833	0.215622500345222	NA	NA	0.938031601118284	0.389854864327907	71.1596522443059
a2872	loss_cnaOV42	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.35134276657939	3.74880120872538	0.602541557854015	1.17895647619017	0.795682870550876	0.699859221674026	0.511080408838454	0.75726345275833	0.215622500345222	NA	NA	0.938031601118284	0.389854864327907	71.1596522443059
a2873	gain_cnaOV48_(SOX17)	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	0.665495559594012	1.37655323656392	-0.711057676969911	1.03327054323287	1.2207003730152	0.588083868665973	0.688162148458403	0.582499762176331	0.215788191483653	NA	NA	0.0910693561578645	0.357021678466442	71.1596522443059
a2874	loss_cnaOV83	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	5.09857186836429	4.42643787430555	0.672133994058741	0.876388122522725	0.977086720492592	0.696739931565327	0.766936448344337	0.687895946144769	0.215910526697222	NA	NA	0.316075665077825	0.172378481280031	71.1596522443059
a2875	loss_cnaOV42	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	4.79796749253024	5.24691818962639	-0.448950697096144	0.863066586016478	0.750427766352138	0.58883348119952	0.520180834677306	0.598259708963746	0.21598394366251	NA	NA	0.323854344245565	0.383451342097474	71.1596522443059
a2876	loss_cnaOV102	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.93199575291613	3.9396582590921	0.992337493824025	0.750280492756079	1.51887782676464	0.67044955150216	1.3226220105747	0.653335953911317	0.216018846900511	NA	NA	0.31998592023553	0.127236648327046	71.1596522443059
a2877	loss_cnaOV57_(ZNRF3)	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.77206595061733	3.85075817091391	0.921307779703428	0.721865976469296	1.17134631993934	0.813052445223773	1.27628647108376	0.786537477448294	0.216059539534067	NA	NA	0.0767980223562044	0.0759817642330065	71.1596522443059
a2878	gain_cnaOV48_(SOX17)	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	2.87730000362407	3.54223822593935	-0.664938222315285	1.09214221872492	0.875325574713345	0.746360579171768	0.608838492748319	0.759646743479466	0.216122596535019	NA	NA	0.790200008585092	0.403266727677739	71.1596522443059
a2879	loss_cnaOV35	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.25681401344591	4.53423465913723	-0.277420645691318	0.610151490674947	0.683726953088628	0.411568983443526	0.454675027318932	0.405747710307623	0.216159496422563	NA	NA	0.0488117843136483	0.396109369548398	71.1596522443059
a2880	loss_cnaOV82	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	0.12567603295131	-1.46668268483831	1.59235871778962	2.11765456430898	1.80271814443791	0.872331672901647	0.751944507204948	0.88330986333203	0.216183749288009	NA	NA	0.0686466261451226	0.321120937801706	71.1596522443059
a2881	loss_cnaOV21, loss_cnaOV22	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.1388934559154	2.86376351189387	-0.724870055978472	1.30616432489924	0.915826690515667	0.766342008309725	0.554960843869617	0.791492608247009	0.216290076084531	NA	NA	0.965518937990635	0.439213812494474	71.1596522443059
a2882	loss_cnaOV70	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.94942701372043	4.47134734941821	0.478079664302227	0.209281796598943	0.604715796470703	0.814855729977012	2.28438245500345	0.790585705041011	0.216307827299358	NA	NA	0.607792535829456	0.0246168017838061	71.1596522443059
a2883	BRCA1_mut	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	2.45354388303686	1.61534019523365	0.838203687803212	2.21028724843566	1.49748029743067	0.528453690285203	0.379228395945574	0.559742715307423	0.216399761089935	NA	NA	0.0373625992150679	0.510108312720287	71.1596522443059
a2884	gain_cnaOV4_(KRAS)	1375	Temozolomide	DNA akylating agent	7	26	3.40119738166216	NA	6.24466214861161	5.86714251747564	0.377519631135965	0.73145545116695	0.679864389163528	0.547010346528054	0.516121153425923	0.555286667684488	0.21647013612113	NA	NA	0.906884937728083	0.249896343153299	71.1596522443059
a2885	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.7680377547325	2.28631683946014	0.481720915272356	0.719555786187556	0.878571110206932	0.560746085946667	0.669469865324372	0.548300427450767	0.216533517447961	NA	NA	0.600563478551997	0.230198942989904	71.1596522443059
a2886	PIK3R1_mut	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-4.72996131475074	-3.10559200393286	-1.62436931081788	0.664796093011906	1.83428375275586	0.928248240879308	2.44340983331981	0.885560540116761	0.216562455146963	NA	NA	0.131504391537546	0.00587739149894233	71.1596522443059
a2887	gain_cnaOV26	219	AT-7519	CDK9	3	29	2.32630161961136	NA	2.76659045324725	1.36644397359346	1.4001464796538	2.19207030393537	1.62220709871534	0.840286678635589	0.638732470003423	0.863112040850146	0.216617342450714	NA	NA	0.306405222276854	0.384242457378313	71.1596522443059
a2888	loss_cnaOV102	310	YM201636	FYV1	3	29	1.63315443905142	NA	1.73520553536445	2.42123150635605	-0.686025970991608	0.850285531664765	0.850078584315888	0.807001668543897	0.806818351534743	0.807014767397883	0.216645191922894	NA	NA	0.643869415222972	0.294344807725996	71.1596522443059
a2889	loss_cnaOV20	157	JNK-9L	JNK	4	15	1.63315443905142	NA	0.396198515356665	-0.145552360925198	0.541750876281862	1.10172073367714	0.968995312360235	0.545182008265767	0.491731579266642	0.559085136296779	0.216667255531568	NA	NA	0.174959679768449	0.417591896120446	71.1596522443059
a2890	NF1_mut	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.52879534191909	4.6418338677039	0.886961474215195	0.336547145869163	1.2618283064214	0.739335804260645	2.63547465816279	0.702917718441948	0.216886161722785	NA	NA	0.415156465090588	0.00732722668140692	71.1597719933528
a2891	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	326	GSK690693	AKT	7	25	2.32630161961136	NA	4.71291814437527	3.9948547899345	0.718063354440768	0.987503598880982	1.52962983958963	0.499469114623474	0.72715011393828	0.469436026845168	0.216912798845549	NA	NA	0.0873077099258043	0.157398618072015	71.1597719933528
a2892	loss_cnaOV20	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.47336981976869	1.35654944693993	1.11682037282875	1.91608282440422	1.88455910078541	0.591287966604424	0.582866439072651	0.592616263593596	0.217021502240711	NA	NA	0.778244246229557	0.278886863661095	71.1597719933528
a2893	loss_cnaOV56	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.75608537762167	3.40904042647813	1.34704495114355	0.587675232915477	1.72700900662437	0.804914967218944	2.29215879059733	0.779987218350699	0.217022310746768	NA	NA	0.692437786490957	0.0244008596039175	71.1597719933528
a2894	gain_cnaOV72_(ASXL1)	157	JNK-9L	JNK	4	15	1.63315443905142	NA	0.639616709845918	-0.210463879455665	0.850080589301583	0.904135994194269	0.962849878625658	0.892237414289908	0.940213192219099	0.882879676440278	0.217190171090857	NA	NA	0.175005157824693	0.160433047803525	71.1597719933528
a2895	loss_cnaOV42	293	MP470	PDGFR	4	28	2.99573227355399	NA	5.01518489058592	3.91125098996447	1.10393390062145	1.24183573286981	1.78792098345906	0.63406677009635	0.888953241883551	0.61743998243462	0.217292268628749	NA	NA	0.615099257426828	0.17922679002196	71.1597719933528
a2896	loss_cnaOV81_(RB1)	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	5.68400500679336	5.12034140187451	0.563663604918842	0.488493575409449	0.777389830114615	0.748059337988642	1.15388130631275	0.725072007741262	0.217309084828276	NA	NA	0.32392779417116	0.0998476025531296	71.1597719933528
a2897	BRCA1_mut	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	4.78053827549478	3.48426048605363	1.29627778944115	0.83824770491982	2.0847140131569	0.649627011818997	1.54641376508766	0.62180125487725	0.21751549047634	NA	NA	0.742410409879276	0.0484232226891852	71.1597719933528
a2898	loss_cnaOV35	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.02525816181697	4.5063542916663	-0.481096129849336	1.17348311350363	0.62382042155219	0.666600747785261	0.409972776185029	0.77120933080753	0.217523505609533	NA	NA	0.51593454125289	0.417435726497668	71.1597719933528
a2899	gain_cnaOV49	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.14083233316925	2.86356962416848	-0.722737290999234	0.772219012040268	0.956850501164867	0.763971263839118	0.93592268479599	0.755329374985304	0.217673878652946	NA	NA	0.9655242954006	0.239602433457115	71.1597719933528
a2900	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	293	MP470	PDGFR	7	25	2.99573227355399	NA	4.79693036160188	3.83989019000543	0.957040171596448	1.00735665321229	1.87198755619611	0.551956808831944	0.950050976031781	0.511242806304311	0.217738121847674	NA	NA	0.615117455412549	0.0891873126162597	71.1597719933528
a2901	NF1_mut	219	AT-7519	CDK9	4	28	2.32630161961136	NA	2.35691014296521	1.37496450078897	0.981945642176237	2.23161032640984	1.61370013804759	0.582510010503717	0.440016624119124	0.608505644279296	0.217776939899483	NA	NA	0.306469200207518	0.450615012418157	71.1597719933528
a2902	loss_cnaOV70	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.87822328643696	1.8422187841421	1.03600450229486	0.414763107203351	1.35825474324415	0.786901730898526	2.49782221297451	0.762746831879561	0.217832916709917	NA	NA	0.835798802423899	0.0171976382776567	71.1597719933528
a2903	gain_cnaOV94	283	GSK2126458	PI3K, MTOR	7	25	-2.05572501506252	0.0237165266173161	-1.95874033283158	-2.94874690331023	0.990006570478652	0.984063433610197	1.87342963826178	0.571440854431236	1.00603938391111	0.528446091734306	0.217961275607404	NA	NA	0.690382178236205	0.0759238719301839	71.1597719933528
a2904	loss_cnaOV102	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	3.01246985209142	2.32950545531634	0.682964396775079	1.06367428596975	0.917395558466432	0.736059930087169	0.642080386621756	0.744460108262088	0.217985225329865	NA	NA	0.729593425195653	0.382615985767589	71.1597719933528
a2905	loss_cnaOV52, loss_cnaOV53	1024	CEP-701	FLT3, JAK2, NTRK1, RET	8	23	0.693147180559945	NA	0.618434525749953	-0.427764144488532	1.04619867023848	0.946074614648737	1.6995387792093	0.674297464651465	1.1058310349305	0.615577992710012	0.217991373623532	NA	NA	0.0938837052385335	0.0428177222104867	71.1597719933528
a2906	loss_cnaOV57_(ZNRF3)	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	1.55179904754975	2.40908635398759	-0.857287306437836	1.14076509154992	1.24210613577085	0.695844885801543	0.751502051375948	0.690188448272823	0.218006834547049	NA	NA	0.841261641847952	0.235809331880884	71.1597719933528
a2907	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	298	OSI-930	KIT, VEGFR, PDGFR	7	25	2.32630161961136	NA	4.81291048052763	4.35038970273662	0.462520777791007	1.20449027410819	0.905245575340611	0.475605113309896	0.383997104612123	0.510934038663462	0.218017574163638	NA	NA	0.0282448699929949	0.372786332620434	71.1597719933528
a2908	loss_cnaOV44	304	SB52334	ALK5	3	29	2.99573227355399	NA	5.01672734912176	4.29939011022124	0.71733723890052	0.979997961876798	1.05397595385922	0.683695080151471	0.731978296696398	0.680601143008937	0.218264459847128	NA	NA	0.342207123444783	0.331871540193814	71.2130946523257
a2909	PIK3R1_mut	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	1.7856040555194	0.494398143773717	1.29120591174568	1.43087681319265	2.38267948907287	0.566602143118503	0.902387892403307	0.541913386868539	0.218518063569689	NA	NA	0.944734901527691	0.136136439791273	71.2130946523257
a2910	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.97584049759392	4.33966437134013	0.636176126253797	1.0018852905661	0.835031622721554	0.751280492161579	0.634979006323507	0.761858723601818	0.218575254919751	NA	NA	0.866973660776708	0.386823935069932	71.2130946523257
a2911	SMAD4_mut	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	3.056622965651	2.44353442056105	0.613088545089954	0.608561158011986	1.06435530288923	0.597984300845399	1.00743949399064	0.576018687956648	0.218625983419304	NA	NA	0.186345328276672	0.145164823921249	71.2130946523257
a2912	loss_cnaOV43_(NF1)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	4.23049828584018	3.32067682215148	0.9098214636887	1.02015386733136	1.07712778189004	0.84983790609258	0.891847291692104	0.844673658024339	0.218822070474444	NA	NA	0.764703424909548	0.257443055297034	71.2130946523257
a2913	loss_cnaOV83	1262	UNC1215	LMBL3	5	28	0	NA	3.07984620533864	2.72694243653968	0.352903768798952	0.659614692687319	0.449041378004013	0.733053975000678	0.535015021210634	0.785904787589081	0.219122285765302	NA	NA	0.103189404322932	0.305554324306261	71.2130946523257
a2914	loss_cnaOV84	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	0	NA	-3.05912127356463	-1.75217643755318	-1.30694483601145	2.67382791830851	1.81994677177984	0.659174104430118	0.488791678425678	0.718122560657808	0.219181820562543	NA	NA	0.269167518056992	0.297246047449197	71.2130946523257
a2915	loss_cnaOV38	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	5.76065185311272	6.94750574290778	-1.18685388979507	1.11038416234821	1.51008815381111	0.819880318467112	1.06886781173567	0.785950069735812	0.219251947002225	NA	NA	0.319591291626877	0.12800777769063	71.2130946523257
a2916	loss_cnaOV85	1527	GDC0941 (rescreen)	PI3K	6	25	1.38629436111989	NA	0.783220569742569	0.286055823446755	0.497164746295814	0.588366469487623	0.947848594426982	0.554737731763339	0.844991637148814	0.524519157615434	0.219262219633045	NA	NA	0.907758015002702	0.129787461251433	71.2130946523257
a2917	loss_cnaOV40	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	3.3892091432917	4.07462997699159	-0.685420833699891	1.07265480555744	1.22557467391968	0.573313917374817	0.638994791379961	0.559264847981685	0.21939639761074	NA	NA	0.692746552996015	0.178004485771489	71.2130946523257
a2918	MLL2_mut	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	3.6756653433913	4.61353745974009	-0.937872116348798	0.81611190387165	0.965520413415534	0.980437186065619	1.14919548642719	0.97136435782965	0.219450169581072	NA	NA	0.316264187137362	0.173316220077529	71.2130946523257
a2919	loss_cnaOV102	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.298900166236	4.45451314290277	0.844387023333236	1.07266861737421	0.987665850255577	0.849860997688893	0.787183487664827	0.854931881176954	0.219483086773612	NA	NA	0.182754190973796	0.303701739490547	71.2130946523257
a2920	gain_cnaOV19	306	TG101348	JAK2	3	29	2.32630161961136	NA	1.91920658810546	2.91766400067192	-0.998457412566463	1.13325135756643	1.39168878957817	0.725638625366632	0.881055562739917	0.717443023212902	0.219484029254241	NA	NA	0.620507940464817	0.261416244240838	71.2130946523257
a2921	loss_cnaOV42	304	SB52334	ALK5	4	28	2.99573227355399	NA	4.90647244440016	4.28952162379216	0.616950820607997	0.829993120201886	1.07195132650977	0.587422898525979	0.743320403014824	0.575539957226198	0.219487117601581	NA	NA	0.342273994027841	0.244200629580029	71.2130946523257
a2922	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.55479784097594	2.07136358595675	0.483434255019199	0.623849777377988	0.539220237533571	0.886910238104891	0.77492093858084	0.8965432329292	0.21952435038249	NA	NA	0.0386966178304677	0.309713548535443	71.2130946523257
a2923	loss_cnaOV81_(RB1)	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.36047926759855	5.89022149738806	0.470257770210487	0.282759047798372	0.72047530153208	0.681183972711021	1.66310423617573	0.652704914672981	0.219694768746846	NA	NA	0.906918307129137	0.0364827580089279	71.2130946523257
a2924	gain_cnaOV48_(SOX17)	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.12503536489943	4.52619726335572	-0.401161898456295	0.120896344333877	0.718632663419575	0.576595367880194	3.31823018029737	0.558229424957374	0.219711911791634	NA	NA	0.0759512699573519	0.0130710244400506	71.2130946523257
a2925	loss_cnaOV55	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	1.98523665867601	2.50785644598864	-0.52261978731263	1.08663105915613	0.878394840388826	0.565725309906673	0.480954214320444	0.594971376518206	0.219752697601273	NA	NA	0.72964616785451	0.274417449369648	71.2130946523257
a2926	gain_cnaOV19	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	1.64527355236371	2.3634903486297	-0.718216796265988	2.09712311392335	0.713111822590607	0.814913223338751	0.342477173370298	1.00715872814566	0.219752826508381	NA	NA	0.586713150065615	0.613945643229184	71.2130946523257
a2927	gain_cnaOV49	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-2.75944205364676	-1.95113465206014	-0.808307401586621	1.04031373148479	1.58582194521699	0.520026110265414	0.77698426649907	0.50970880055265	0.219880175189544	NA	NA	0.0342730808483099	0.312204756598608	71.2130946523257
a2928	gain_cnaOV72_(ASXL1)	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	4.48217289473	3.39972949982713	1.08244339490287	1.16568473231345	1.73180853687515	0.643506016370185	0.928590179571642	0.625036412429295	0.21996120960478	NA	NA	0.692540012304614	0.165392554527772	71.2130946523257
a2929	gain_cnaOV18_(CCNE1)	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.79471502710806	0.828838336066224	0.965876691041841	1.07337903455671	1.25741321985778	0.775698473417433	0.899846801498908	0.76814580584025	0.220054468873027	NA	NA	0.956547620027725	0.253725403218543	71.2130946523257
a2930	gain_cnaOV19	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.79471502710806	0.828838336066224	0.965876691041841	1.07337903455671	1.25741321985778	0.775698473417433	0.899846801498908	0.76814580584025	0.220054468873027	NA	NA	0.956547620027725	0.253725403218543	71.2130946523257
a2931	gain_cnaOV18_(CCNE1)	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.70933572922398	3.91411823340089	0.795217495823091	1.08487436435434	1.01630789959012	0.777056673812671	0.733004227910173	0.782457261371092	0.220097937096061	NA	NA	0.098157296547832	0.242798407612879	71.2130946523257
a2932	gain_cnaOV50	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.47029531140266	5.75004171698568	-0.279746405583023	0.175863433522437	0.494432606959013	0.592249851746603	1.59070251262513	0.565792792881505	0.220137277629472	NA	NA	0.372296661405718	0.050027461291684	71.2130946523257
a2933	loss_cnaOV85	1066	AZD6482	PI3Kbeta	7	26	1.6094379124341	NA	3.04625735688308	2.19949803143392	0.846759325449152	1.28608230582714	1.26402632286749	0.667620066424378	0.658402126840987	0.669890579120413	0.220323393815063	NA	NA	0.103551812202993	0.153776461423844	71.2130946523257
a2934	loss_cnaOV82	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.57230353463205	4.84008330126068	0.732220233371372	0.852057210047065	0.836996567170282	0.87372536748246	0.859355715481741	0.874818681571015	0.220349317155451	NA	NA	0.146089188223558	0.271001869035527	71.2130946523257
a2935	loss_cnaOV59	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.57715365836343	2.52793146654269	1.04922219182074	1.85201885453286	1.66067881954226	0.624481929690451	0.566528893187421	0.631803199675863	0.220414867386288	NA	NA	0.633553635235071	0.347457150947744	71.2130946523257
a2936	gain_cnaOV95_(MECOM)	1018	ABT-888	PARP1, PARP2	8	23	1.6094379124341	NA	4.61405640391475	4.19020345293119	0.42385295098356	0.737700894444174	0.7994852447	0.539928286245744	0.574559356204815	0.530157315339331	0.220453263877782	NA	NA	0.215797875275593	0.193776055698103	71.2130946523257
a2937	loss_cnaOV21, loss_cnaOV22	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.63658107784472	5.73815734353438	0.898423734310343	0.442522119284126	1.30789761021265	0.708142544923798	2.03023463722838	0.686922070424358	0.220524337481721	NA	NA	0.563256901057985	0.0388849457863987	71.2130946523257
a2938	loss_cnaOV38	224	AS605240	PI3Kgamma	8	24	2.99573227355399	2.32630161961136	3.94102544681508	3.18645961310814	0.754565833706947	1.31444473928983	1.73732600670658	0.457760397448721	0.5740567185157	0.434325987635081	0.220593698201067	NA	NA	0.622901492869186	0.215247828151496	71.2130946523257
a2939	loss_cnaOV16, loss_cnaOV17	1053	MK-2206	AKT1, AKT2	6	26	1.38629436111989	0.693147180559945	1.9868401066285	1.15367268843711	0.833167418191399	1.01549201707057	1.21149128823294	0.705425067817395	0.820456886106177	0.68772051956448	0.22063094524144	NA	NA	0.091241636346853	0.116597733960895	71.2130946523257
a2940	ARID1A_mut	281	CH5424802	ALK	8	24	1.63315443905142	NA	3.70813550816932	4.0007623712079	-0.292626863038573	0.888854737042181	0.665632965865447	0.404235946847365	0.329217869741393	0.439621950902181	0.220657713074695	NA	NA	0.954897954770674	0.413207767309858	71.2130946523257
a2941	loss_cnaOV44	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.49273833005338	0.682284333848071	0.81045399620531	0.51290847866115	1.0552377880117	0.788362211995154	1.58011425024762	0.768029732646692	0.220750647649838	NA	NA	0.76746987234149	0.0832761464742845	71.2186460022109
a2942	loss_cnaOV34	310	YM201636	FYV1	5	27	1.63315443905142	NA	1.89199401768185	2.44301334081517	-0.55101932313332	1.24200841336275	0.77230910906865	0.648208161901623	0.443651844226587	0.713469926306852	0.220853924960049	NA	NA	0.644029481177372	0.385615845121366	71.2186460022109
a2943	loss_cnaOV39	1371	PLX4720 (rescreen)	BRAF	10	23	2.30258509299405	NA	4.9090197523234	4.36273575213664	0.546284000186761	0.884877225303122	0.991753460582589	0.567892937358266	0.617355701520769	0.550826411904684	0.220900092723316	NA	NA	0.316340366487912	0.13276167889975	71.2186460022109
a2944	TP53_mut	158	PF-562271	FAK	12	6	0.940007258491471	NA	2.57136669439205	1.72558611017205	0.845780584220005	1.29727356842457	1.45702537455238	0.62686194828696	0.651967792149759	0.580484457574968	0.221124734170083	NA	NA	0.737188939630682	0.259239076920025	71.2602284373016
a2945	loss_cnaOV54	260	NG-25	MAP3K7 (TAK1)	10	22	2.32630161961136	NA	3.29315130543237	2.88417738241479	0.408973923017579	0.933035405471747	1.12782695415788	0.381111401986274	0.438326263525659	0.362621164097777	0.221277602454109	NA	NA	0.425455212159437	0.294817608240429	71.2602284373016
a2946	loss_cnaOV20	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	2.62999909310906	1.65559719882453	0.974401894284531	1.62734757992961	1.63650152130881	0.596004616287848	0.598766917591556	0.595417652594202	0.221351777162626	NA	NA	0.328699670238296	0.338780666354505	71.2602284373016
a2947	loss_cnaOV1	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.2615738097536	4.03714052861133	1.22443328114227	0.346377041648515	1.47004815226066	0.860450248281769	3.53497239688524	0.832920526623102	0.221397477524278	NA	NA	0.087462757051661	0.00307098019966134	71.2602284373016
a2948	loss_cnaOV43_(NF1)	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	2.53319932205033	1.38604617301105	1.14715314903927	0.604084397768851	1.67736588658833	0.727406691959381	1.89899483131201	0.683901561496831	0.221588562978857	NA	NA	0.0733049912464091	0.0139115059087929	71.2602284373016
a2949	gain_cnaOV48_(SOX17)	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	1.90734122330555	2.60001493435004	-0.692673711044492	0.431309467583394	1.05188007265331	0.676925617250684	1.60597845191182	0.658510156293063	0.221674960443021	NA	NA	0.386156529066211	0.0792039145060758	71.2602284373016
a2950	NF1_mut	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	1.8864604216171	2.6235594273355	-0.737099005718392	1.39729711005917	0.959053243425222	0.726135490872053	0.527517734354419	0.768569431125504	0.221710155988469	NA	NA	0.18650692703553	0.37437944624311	71.2602284373016
a2951	PIK3CA_mut	1175	AG-014699	PARP1, PARP2	7	26	1.6094379124341	NA	3.32651034518863	4.05587074440735	-0.729360399218717	0.917193475865956	1.06596867538832	0.702092765041829	0.795208882760642	0.684223107168716	0.22174731786419	NA	NA	0.30729642730055	0.0995082551485876	71.2602284373016
a2952	loss_cnaOV40	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	8	25	0.693147180559945	NA	2.44265669177092	2.91153328761579	-0.468876595844872	1.30029255136857	0.816517914524576	0.494805742487358	0.360593156787198	0.574239202232175	0.22197184206068	NA	NA	0.965540674260656	0.362070939676074	71.2602284373016
a2953	loss_cnaOV43_(NF1)	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.34649614767863	3.69996767723667	0.646528470441959	1.07550488172481	1.00072895768731	0.639482225923362	0.601139503342012	0.646057521844967	0.222037209071109	NA	NA	0.711795572458733	0.263783824179561	71.2602284373016
a2954	loss_cnaOV83	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	0.0431607097643671	-0.732722164817629	0.775882874581996	2.02947092716001	1.82124162587433	0.417212446832048	0.382307952382322	0.426018636714124	0.222131158157718	NA	NA	0.0363526047838887	0.522862357646856	71.2602284373016
a2955	loss_cnaOV54	1219	PFI-1	BRD2, BRD3, BRD4	10	22	2.30258509299405	NA	2.59774621510323	2.25424005854791	0.343506156555317	0.728020205031834	0.913854860805574	0.398351211952934	0.471836020732826	0.375886993972448	0.222255285080585	NA	NA	0.600801511557834	0.267123823523232	71.2602284373016
a2956	loss_cnaOV38	345	KIN001-270	CDK9	8	24	2.99573227355399	NA	4.95901850354285	5.26805963547154	-0.309041131928688	0.894275323584265	0.721525943824178	0.403801250204769	0.345577165978424	0.428316035721088	0.222271246081088	NA	NA	0.324198165446505	0.395971169680198	71.2602284373016
a2957	NF1_mut	305	TPCA-1	IKK	4	28	2.99573227355399	NA	4.0356298854795	3.22370431514156	0.811925570337936	1.03974586633935	1.22668796130055	0.671404111136836	0.780888481140586	0.661884355233358	0.222302692661016	NA	NA	0.993483932647025	0.222244486339551	71.2602284373016
a2958	loss_cnaOV16, loss_cnaOV17	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	3.05189582112281	1.95730104697633	1.09459477414648	1.24491441428932	1.31878624910899	0.835708789412893	0.879253032644294	0.83000165863575	0.222419768738069	NA	NA	0.887998861210424	0.263123777086207	71.2602284373016
a2959	loss_cnaOV102	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.33520085674118	4.81091178323825	0.524289073502931	0.507308510569788	0.611666498364514	0.86620788364308	1.03347186688051	0.857148584898447	0.22263215198116	NA	NA	0.045557219510189	0.205873915409348	71.2602284373016
a2960	PIK3R1_mut	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.16248457112422	1.59492743133671	0.567557139787504	1.48852749542995	1.48000976203285	0.383187249803319	0.38128764267372	0.383482024475258	0.222645385403101	NA	NA	0.31704446562621	0.46514360546339	71.2602284373016
a2961	loss_cnaOV81_(RB1)	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	3.31628424074644	2.43739015092415	0.878894089822293	1.35423761682391	0.980224473476113	0.868870533927	0.64899547827032	0.896625327773669	0.222728266064051	NA	NA	0.186559693438365	0.378026809580684	71.2602284373016
a2962	loss_cnaOV20	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	3.11890828555149	2.43314036688073	0.685767918670757	0.769030224658362	1.04362162085293	0.677379125629952	0.891730775569199	0.657103978078081	0.222795223340237	NA	NA	0.386213902549293	0.127594524537406	71.2602284373016
a2963	loss_cnaOV83	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	0.870730882900612	-0.0818298394901193	0.952560722390731	1.55167044979101	1.21964185685882	0.741588519610246	0.613893705663485	0.781016752609692	0.222909890560376	NA	NA	0.865117470143434	0.318113700172569	71.2602284373016
a2964	gain_cnaOV95_(MECOM)	1199	Tamoxifen	ER	8	24	1.6094379124341	NA	4.27516357113376	3.88140588723905	0.393757683894707	0.475937593020125	0.812144079010515	0.526872651657878	0.827330493891155	0.48483722786534	0.222912993987561	NA	NA	0.517427601131769	0.110281682088421	71.2602284373016
a2965	loss_cnaOV35	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	3.28598995571284	2.71070128378564	0.575288671927198	1.14084172945981	0.914055210086774	0.607885478331492	0.504266855841255	0.629380660575836	0.222915718669556	NA	NA	0.965544219466013	0.334711608908047	71.2602284373016
a2966	TP53_mut	1373	Dabrafenib	BRAF	23	9	2.30258509299405	NA	3.89930527084898	2.99971394243938	0.899591328409602	1.99127515909344	2.02679590599609	0.449613791259689	0.451766459447602	0.443848996215279	0.222962287403339	NA	NA	0.742564696559174	0.275101215924719	71.2602284373016
a2967	gain_cnaOV4_(KRAS)	1262	UNC1215	LMBL3	7	26	0	NA	2.98147848874932	2.72627960879073	0.255198879958587	0.393682471799775	0.506906494380165	0.523967782658769	0.648235312057226	0.503443697778304	0.223061834556181	NA	NA	0.103332142607681	0.179383137324216	71.2602284373016
a2968	gain_cnaOV26	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-0.802821115932986	-2.10850093691749	1.3056798209845	2.8933474619069	1.93744419228789	0.648668550041554	0.451269623913049	0.673918673983921	0.223200647180835	NA	NA	0.269374545895678	0.518491753939351	71.2602284373016
a2969	loss_cnaOV57_(ZNRF3)	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	-0.074377564335916	-1.49497355371834	1.42059598938242	1.8962109975652	1.81563807078569	0.778897205578679	0.749176115530667	0.782422450950087	0.223241648807581	NA	NA	0.0688582784093975	0.234636200761683	71.2602284373016
a2970	gain_cnaOV95_(MECOM)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	9	23	1.63315443905142	NA	2.59337453083176	2.96957320621591	-0.376198675384146	0.455345893034154	0.881770490167014	0.475678520322094	0.826182208161319	0.426640128672134	0.223259410556358	NA	NA	0.0173958327721779	0.126100972428062	71.2602284373016
a2971	gain_cnaOV19	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.38262021685085	2.89945557849857	0.483164638352278	0.390888015500835	0.601911335553993	0.831499374253363	1.23606920445799	0.80271729374822	0.22345673049773	NA	NA	0.844064681573419	0.148288581230273	71.2602284373016
a2972	loss_cnaOV44	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.98981559997574	1.11403879210672	1.87577680786902	1.82019921766282	2.30670223071257	0.823610706787408	1.03053379523894	0.813185500449085	0.223458216340222	NA	NA	0.354169828896391	0.206376130962863	71.2602284373016
a2973	KRAS_mut	301	PHA-793887	CDK-pan	7	25	2.32630161961136	NA	2.29856213869294	3.20899716727218	-0.910435028579243	1.44112175870609	1.62417288748757	0.572870769561203	0.631754411505573	0.560553027078044	0.223464788302134	NA	NA	0.657219823610469	0.179736409068828	71.2602284373016
a2974	loss_cnaOV55	283	GSK2126458	PI3K, MTOR	7	25	-2.05572501506252	0.0237165266173161	-3.40251226168107	-2.54449076323238	-0.858021498448697	1.49392296047389	1.80262622304026	0.491629795847803	0.574341195061708	0.475984143291547	0.223481621045919	NA	NA	0.690566314824762	0.225688328240725	71.2602284373016
a2975	MLL2_mut	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	1.67540274549292	3.16801468311352	-1.4926119376206	1.53428463395086	1.07494233514788	1.34140169424035	0.972839005613354	1.38855070529459	0.223537661649029	NA	NA	0.0825187373261604	0.230069019845786	71.2602284373016
a2976	NF1_mut	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.913227917814886	0.303622493828324	0.609605423986562	0.963768284234426	0.885951467640798	0.681644677180778	0.6325228106783	0.688079930168051	0.223561176511504	NA	NA	0.907804441012693	0.302282585370034	71.2602284373016
a2977	gain_cnaOV48_(SOX17)	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.13616777442597	4.55547761555212	-0.41930984112615	0.307209396147394	0.605961492933671	0.709775771148235	1.3648991417078	0.691974401040114	0.223582582541084	NA	NA	0.608089939579699	0.118629286142583	71.2602284373016
a2978	TP53_mut	1022	AZD7762	CHEK1, CHEK2	21	10	0.693147180559945	NA	-0.718901665124753	-1.0181552476254	0.29925358250065	0.650147017511345	1.0608229283661	0.373846175416963	0.460286019070184	0.282095696179536	0.223806963237771	NA	NA	0.0731264556161249	0.426901578659477	71.2856833865112
a2979	loss_cnaOV43_(NF1)	1006	Cytarabine	DNA synthesis	5	26	0.693147180559945	NA	0.547025917143517	-0.237912225954393	0.78493814309791	1.36052495942738	1.2134856704476	0.63567608010238	0.576937701626785	0.646845827860811	0.223914852763901	NA	NA	0.762506055433959	0.280523309024732	71.2856833865112
a2980	loss_cnaOV41	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	3.2431903564704	2.18332259420212	1.05986776226828	2.13621541199284	1.40075514971109	0.699195638148147	0.496142737440297	0.756640275416357	0.223930167986574	NA	NA	0.233479145218304	0.337514165300426	71.2856833865112
a2981	gain_cnaOV72_(ASXL1)	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	1.84657871091601	3.02888839611558	-1.18230968519958	2.15815994584334	1.75616192315741	0.651441311066053	0.547832280678144	0.673235007324324	0.224004598882139	NA	NA	0.337018675164543	0.299566984353425	71.2856833865112
a2982	gain_cnaOV72_(ASXL1)	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.93744909388861	3.40042147570035	0.537027618188263	0.887651443100626	0.891021771658308	0.603003695327723	0.604998304641278	0.602709872272575	0.224038099472716	NA	NA	0.790378922936645	0.263046639937904	71.2856833865112
a2983	loss_cnaOV56	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.45208095519839	2.73244476196557	0.719636193232827	1.52388353646792	0.89272393763559	0.760526058662186	0.472238314812962	0.806112800267021	0.224162507848839	NA	NA	0.965548874403521	0.500848770474922	71.2863080906806
a2984	loss_cnaOV33_(ZFHX3)	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	2.67119334329445	3.39261945638492	-0.721426113090465	1.06596028660542	1.09106591110285	0.662721327371687	0.676785169349848	0.661212219856861	0.224190324417259	NA	NA	0.949957516030301	0.27610824957163	71.2863080906806
a2985	SMARCA4_mut	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	3.47733127256715	4.30452378231466	-0.827192509747509	1.61966381923333	0.891414512712225	0.865897297999931	0.510718644156082	0.927954950195601	0.224267984320693	NA	NA	0.201247562138317	0.470756667290204	71.2871120042174
a2986	loss_cnaOV58	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	3.04876534146449	2.65441929694054	0.394346044523945	0.682705341538387	0.532353695275323	0.710840862527598	0.577622614809689	0.740759476310194	0.224419513642836	NA	NA	0.128341571394693	0.275907226879819	71.2993051274665
a2987	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	4.22577359641661	3.58065150170664	0.645122094709968	1.06018151591756	1.02960269320463	0.624070853136334	0.60850154904996	0.626573822084738	0.224525363743806	NA	NA	0.827704120174592	0.260080121722632	71.2993051274665
a2988	gain_cnaOV48_(SOX17)	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-1.18588569307725	-0.69584309208481	-0.490042600992442	0.412589765588244	0.944712400889733	0.532817228958821	1.1877235982666	0.518721465422618	0.224573007332866	NA	NA	0.0384340627149321	0.162153299153831	71.2993051274665
a2989	loss_cnaOV16, loss_cnaOV17	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.78703605408632	4.89013682804929	0.896899226037029	0.958119953337383	1.17417681271679	0.779325813324957	0.936103274869596	0.763853634583195	0.224750159836555	NA	NA	0.793658260564029	0.240791461826675	71.2993051274665
a2990	gain_cnaOV95_(MECOM)	260	NG-25	MAP3K7 (TAK1)	9	23	2.32630161961136	NA	2.63070329883376	3.16117764251936	-0.530474343685605	0.626862053827484	1.18192443472835	0.499201737157164	0.846237765464736	0.448822554216445	0.224775710276264	NA	NA	0.425635428810494	0.112298291363096	71.2993051274665
a2991	loss_cnaOV82	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.48669693797467	0.682909305442421	0.803787632532251	0.510685540390955	1.05580973785428	0.781517060712544	1.57393849827217	0.761299696066249	0.224788469038231	NA	NA	0.767572467226429	0.0840570864347472	71.2993051274665
a2992	loss_cnaOV1	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.76076245000613	2.90908466396986	0.85167778603627	0.319852847336948	1.01221984252784	0.866946138134896	2.66271753754023	0.84139605869547	0.224851364758404	NA	NA	0.082128034658131	0.0126114787957539	71.2993051274665
a2993	gain_cnaOV26	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.06504963585168	-2.42157508840602	1.35652545255435	2.68574053128768	1.47148575228532	0.859500279048057	0.505084328419456	0.921874676970244	0.224943062982117	NA	NA	0.117609876696909	0.475009807140364	71.2993051274665
a2994	NF1_mut	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	3.16401719860156	2.19253455047157	0.971482648129991	0.536465123647021	1.48381139917723	0.685178852122118	1.81089618934706	0.654721111233324	0.224982644202879	NA	NA	0.817485440150304	0.0283333147006415	71.2993051274665
a2995	PIK3CA_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	6	25	3.68887945411394	NA	3.14474548973657	3.57237855304003	-0.427633063303457	1.46667285861516	1.01976617568741	0.385347234167894	0.291566766775264	0.419344231549152	0.225195409353036	NA	NA	0.72147450589567	0.523376994555352	71.3097139659366
a2996	loss_cnaOV33_(ZFHX3)	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.96087841129512	4.42474173621343	0.536136675081692	0.78975894512782	0.669838115575319	0.785703584632221	0.678861161863662	0.800397383509907	0.225235241997028	NA	NA	0.0761189250547501	0.271714059392476	71.3097139659366
a2997	PIK3R1_mut	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	2.92205147899632	3.83297834795387	-0.910926868957554	0.176768605760466	1.27041428965649	0.767211612748278	5.15321634765806	0.717031346682869	0.225358723973236	NA	NA	0.190027926236326	0.00109283600040419	71.3097139659366
a2998	gain_cnaOV51_(MYC)	1527	GDC0941 (rescreen)	PI3K	8	23	1.38629436111989	NA	0.705901428609381	0.26971772068475	0.436183707924631	1.10388900796297	0.82101988928593	0.485999227865226	0.39513366360041	0.531270574095343	0.225363802778694	NA	NA	0.907823584527346	0.330593635748717	71.3097139659366
a2999	gain_cnaOV96	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.7666638243305	4.36905694675639	0.397606877574113	0.480762738338544	0.759837182138823	0.545542988599227	0.827033473825764	0.52327904835469	0.225392398155387	NA	NA	0.516306609958622	0.163470816652668	71.3097139659366
a3000	loss_cnaOV35	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	2.67589052334325	3.82599978128758	-1.15010925794433	3.70139433897745	1.58053538507854	0.575650556103166	0.310723244436057	0.727670679696411	0.22546642179858	NA	NA	0.742634095576778	0.529637691973541	71.3097139659366
a3001	loss_cnaOV55	288	KIN001-055	JAK3, MNK1	7	25	2.32630161961136	NA	3.40989042045479	3.91049500322399	-0.500604582769192	1.12288738919127	0.989369408210985	0.492006454965927	0.445819044356479	0.505983486667942	0.225591997391381	NA	NA	0.711904984335464	0.313532119402763	71.3256553471138
a3002	SMAD4_mut	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	3.08491089157683	1.40081093275441	1.68409995882242	3.91631033535006	1.93702396377399	0.744633887546808	0.430022090849418	0.869426496686808	0.225835294917001	NA	NA	0.600613580291125	0.536457660024046	71.365940609877
a3003	gain_cnaOV72_(ASXL1)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.61393673768396	2.67791759623045	0.93601914145351	2.26169203143654	1.39467205177578	0.6100517700359	0.413857911883337	0.671139240412621	0.226106870209373	NA	NA	0.968223202367356	0.415293910994997	71.365940609877
a3004	loss_cnaOV34	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	1.47220566638869	1.97686946024603	-0.50466379385734	1.60846279984386	1.34086434680883	0.366145298662547	0.313755340755367	0.376371998448916	0.226108459110145	NA	NA	0.031244905966135	0.537185569177587	71.365940609877
a3005	loss_cnaOV36	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	2.85805464678025	3.99499598735535	-1.1369413405751	0.456833918713554	1.6182475506945	0.725992452496239	2.48874108073396	0.702575659754381	0.226257091687483	NA	NA	0.710113620489367	0.0188383258585486	71.365940609877
a3006	loss_cnaOV83	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	4.90018997953397	3.71073762256847	1.1894523569655	1.62594953368618	1.67616839267353	0.712532157509833	0.731543219714146	0.709625812158584	0.22642368686219	NA	NA	0.139570548474962	0.188654152639093	71.365940609877
a3007	loss_cnaOV102	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	3.86586787734938	2.71512575836081	1.15074211898857	2.23257230262135	1.47526347040514	0.749456514047085	0.515433304281987	0.78002481731114	0.226469335960758	NA	NA	0.96822443244241	0.467762628207368	71.365940609877
a3008	loss_cnaOV59	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.1048270439726	-3.49450078478888	1.38967374081628	2.17014643249133	1.7224892930644	0.783336343945105	0.640359433819831	0.806782222921093	0.226518823369478	NA	NA	0.131938415022275	0.295019650729089	71.365940609877
a3009	gain_cnaOV96	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.80653530188494	1.13461441672377	0.671920885161166	0.630108611691935	1.27566239474542	0.547117610278518	1.06635724808928	0.526723126690005	0.226535734390299	NA	NA	0.258232583815814	0.131389475447813	71.365940609877
a3010	loss_cnaOV84	192	LFM-A13	BTK	5	14	2.77258872223978	NA	5.05330275973794	4.60786472882021	0.44543803091773	0.522846612480621	0.7073008357634	0.66633016996658	0.851947818509086	0.629771673374261	0.226649000531015	NA	NA	0.955353441662154	0.170332522035856	71.365940609877
a3011	loss_cnaOV58	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	4.43639760864635	3.36690000119311	1.06949760745325	1.20665517171209	1.73799753380688	0.638596978086065	0.886332427462073	0.615361982194899	0.226683368346875	NA	NA	0.692767710416409	0.134147850651967	71.365940609877
a3012	PTEN_mut	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	4.43424752293769	5.12694496983568	-0.692697446897987	1.00673391832269	0.544442783419825	1.18065450409976	0.688064079585285	1.2723053147053	0.226708132427301	NA	NA	0.104096390717143	0.355229668298881	71.365940609877
a3013	loss_cnaOV55	1264	SGC0946	Q8TEK3 (DOT1L)	8	25	-0.693147180559945	NA	2.39057845849351	2.02722693734728	0.363351521146229	0.275929428455198	0.595631775221683	0.672575178253722	1.31682772359754	0.610027094358753	0.226740459435775	NA	NA	0.0388389399896032	0.0259620098513517	71.365940609877
a3014	loss_cnaOV39	294	MPS-1-IN-1	MPS1	9	22	2.99573227355399	NA	3.95562372728262	4.41812333901581	-0.46249961173319	0.760763763022016	0.810358913818574	0.580310975354343	0.607941169405838	0.570734280633502	0.226781286720071	NA	NA	0.30737689330332	0.151416663879549	71.365940609877
a3015	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.05897408209295	-4.16700137730501	1.10802729521206	2.62546533829193	1.3802739154696	0.738824428465812	0.422030822137199	0.802758990656634	0.226812828361015	NA	NA	0.861371825811324	0.542388551815416	71.365940609877
a3016	NF1_mut	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	3.62202747463441	4.31308956512427	-0.691062090489853	1.13436244732849	0.9376580277826	0.721013046149158	0.609207482244636	0.73700866415456	0.227080382339241	NA	NA	0.201379759864914	0.315654691206278	71.365940609877
a3017	KRAS_mut	1059	AZD8055	MTORC1/2	7	26	0.693147180559945	NA	-0.273556641767494	0.430461190196632	-0.704017831964126	1.07896930190601	1.11608353002989	0.634823887041074	0.652491067837119	0.630793137808666	0.227135574891511	NA	NA	0.139635640386358	0.159951492287413	71.365940609877
a3018	gain_cnaOV94	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	1.14417920193402	1.69801939897885	-0.553840197044834	0.46498876556733	1.37015014356549	0.443297479062407	1.19108296384128	0.404218617679079	0.227234907077304	NA	NA	0.152765192385614	0.165076213106747	71.365940609877
a3019	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	5.0415177617021	4.17688573873823	0.864632022963879	1.06353022832672	1.31048204996931	0.674811251238568	0.812983025714492	0.659781660484499	0.227243107786993	NA	NA	0.362309562339919	0.154957212098488	71.365940609877
a3020	loss_cnaOV40	1133	JNJ-26854165	MDM2	8	25	2.30258509299405	NA	3.47915360735738	2.93624151169358	0.542912095663806	1.10059041372966	0.824773229172785	0.606931577994893	0.493291681347645	0.658256204809564	0.227370089254297	NA	NA	0.230390265467323	0.228914329023004	71.365940609877
a3021	loss_cnaOV57_(ZNRF3)	326	GSK690693	AKT	4	28	2.32630161961136	NA	5.10801476151383	4.01534777546193	1.0926669860519	0.607696372676088	1.48496863216034	0.768503371693032	1.79804756977595	0.735818226989939	0.227548439156746	NA	NA	0.0876696456979143	0.025618291627766	71.365940609877
a3022	loss_cnaOV40	312	AV-951	VEGFR	7	25	-2.05572501506252	NA	0.962589700761904	0.549479202347357	0.413110498414547	0.717647118800164	0.562565990649368	0.692192146634285	0.575645728370271	0.73433251437346	0.227567497043723	NA	NA	0.0134190078612895	0.196319680259524	71.365940609877
a3023	gain_cnaOV51_(MYC)	1058	GDC0941	PI3K (class 1)	8	25	1.38629436111989	0.693147180559945	1.46235988652109	0.645954676466838	0.816405210054249	1.46639644919331	1.25753086229531	0.624347506366665	0.556742489729411	0.649212861912675	0.227893237869376	NA	NA	0.155838442183517	0.185488561750944	71.365940609877
a3024	loss_cnaOV56	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.48195498791715	0.683399852000095	0.798555135917057	0.509084619215743	1.05625040156841	0.776150836002417	1.56860982590134	0.756028243616568	0.227992592354319	NA	NA	0.767652290009263	0.0847489712919143	71.365940609877
a3025	loss_cnaOV57_(ZNRF3)	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	4.00301737305661	2.67860038419551	1.32441698886109	1.00541883409229	1.88112124826338	0.73063655272875	1.31727887319398	0.704057215920438	0.228018112856288	NA	NA	0.337230050172315	0.0710624774436846	71.365940609877
a3026	SMAD4_mut	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.29981571034416	0.21743362524647	1.08238208509769	1.44351815095866	1.66956465191679	0.656936995188959	0.749822289646215	0.648301989297049	0.22816450122419	NA	NA	0.83400129669673	0.238048950015819	71.365940609877
a3027	loss_cnaOV16, loss_cnaOV17	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.79283190539938	1.68596616491287	1.1068657404865	1.85503029975309	1.60124115003236	0.677750235891321	0.596683375270922	0.691254868427615	0.228209633814884	NA	NA	0.32935888596691	0.41445813261321	71.365940609877
a3028	KRAS_mut	305	TPCA-1	IKK	7	25	2.99573227355399	NA	3.81489941910812	3.18807777728499	0.626821641823129	0.766174069478379	1.29917070432545	0.517402200523794	0.818119102164183	0.482478276131223	0.228268794827622	NA	NA	0.993488254193726	0.125762260659562	71.365940609877
a3029	NF1_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	0.144475388892696	0.9727922593495	-0.828316870456804	1.05843915826	1.24141326270953	0.676537680168274	0.782583357760965	0.667237007480415	0.228291216992472	NA	NA	0.841940742996113	0.221280876987152	71.365940609877
a3030	PTEN_mut	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	4.17933405112789	3.47868701286273	0.700647038265159	1.3769495956825	0.840998722994724	0.7900283441932	0.50884000435606	0.833113082229442	0.228309143852812	NA	NA	0.657208022071808	0.47251813662367	71.365940609877
a3031	loss_cnaOV85	1067	CCT007093	PPM1D	7	26	1.88706964903238	NA	4.84747023343877	4.39341278312687	0.454057450311901	0.658034539978289	0.684385360586805	0.668355696999067	0.690020694547253	0.66345289724284	0.228318130631585	NA	NA	0.0762104649721976	0.139829992507405	71.365940609877
a3032	SMARCA4_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	3.95074679369334	4.57176315449925	-0.621016360805905	1.30828885996533	0.873453439523415	0.682333224561506	0.474678322050654	0.710989656351633	0.228403416580415	NA	NA	0.520272479939453	0.499569763592886	71.365940609877
a3033	gain_cnaOV96	163	JQ1	BRD4	4	15	0.940007258491471	NA	1.01225448043149	-0.157820458396095	1.17007493882758	1.48371635039755	1.88543647872461	0.642546777801861	0.788610935313929	0.620585711600886	0.228459856608604	NA	NA	0.568627411042583	0.236113757001747	71.365940609877
a3034	loss_cnaOV41	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	4.69991507155314	3.45118042050797	1.24873465104517	1.25136402188652	2.08003260104281	0.627635422442655	0.9978987961973	0.600343788082519	0.228471426027851	NA	NA	0.742716142360193	0.103745622873693	71.365940609877
a3035	gain_cnaOV94	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	0	NA	-2.95679469660633	-1.72945879150305	-1.22733590510328	1.88968657978986	2.00515459172574	0.618825660411901	0.649491782515472	0.612090414458754	0.228556625579126	NA	NA	0.269643652887937	0.163250839964426	71.365940609877
a3036	gain_cnaOV51_(MYC)	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	0.760170995359908	-0.110384216967777	0.870555212327685	0.97545853443296	1.3676363530953	0.676862303967883	0.892457425505785	0.636539976695854	0.22858324022543	NA	NA	0.865271717690601	0.156917283123325	71.365940609877
a3037	PTEN_mut	272	AR-42	HDAC	3	27	1.63315443905142	NA	1.72244390647576	0.136503760307458	1.5859401461683	2.41042875359278	1.73672255955349	0.88439043704479	0.657949397510478	0.913179907432102	0.228607290307411	NA	NA	0.477146286333705	0.372660467470891	71.365940609877
a3038	loss_cnaOV82	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	4.27088423418228	2.41306451149694	1.85781972268535	1.70878552325303	2.32198032309564	0.812615216209364	1.08721644548381	0.800101406634025	0.228641831327096	NA	NA	0.377009987669891	0.188374894167773	71.365940609877
a3039	loss_cnaOV84	221	TAK-715	p38a	6	26	2.99573227355399	2.32630161961136	4.71292146308245	4.17755996704248	0.535361496039978	1.08994623058826	0.827954326915104	0.610396763220691	0.491181565673232	0.646607522464065	0.228733860391923	NA	NA	0.513621818332637	0.298959591000922	71.365940609877
a3040	PIK3CA_mut	1058	GDC0941	PI3K (class 1)	7	26	1.38629436111989	0.693147180559945	0.0310820565931384	1.06269890798799	-1.03161685139485	0.970232097062415	1.34948038162261	0.80291224485293	1.0632681133909	0.764454871255285	0.228859053568424	NA	NA	0.155879260085958	0.0399931227695887	71.365940609877
a3041	loss_cnaOV102	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.78624472209351	1.43898307294033	1.34726164915318	0.687592738213639	1.62879704960347	0.850785192072624	1.95938900206153	0.82715133200982	0.228861752586133	NA	NA	0.0735251762513897	0.0439120320064148	71.365940609877
a3042	gain_cnaOV96	290	KIN001-260	IKK	5	26	2.99573227355399	NA	5.3241496627406	4.75911118243785	0.565038480302758	0.930913569126999	0.876024780583426	0.639329646094065	0.606972010121891	0.645002850177876	0.228900603115534	NA	NA	0.659126802990401	0.260713941957165	71.365940609877
a3043	SMAD4_mut	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	6.2526123868922	5.46489753103496	0.787714855857245	0.903932435033613	0.96354239410092	0.820806835446206	0.871431121760725	0.817519665641967	0.228960582395868	NA	NA	0.295154830027264	0.265713224355857	71.365940609877
a3044	KRAS_mut	295	NVP-BHG712	EPHB4	7	25	2.32630161961136	NA	3.01891222401574	3.31615066782217	-0.297238443806431	1.42522824938874	0.986538480380233	0.273068218596516	0.208554976323205	0.301294323250188	0.229088405345927	NA	NA	0.0577957143317103	0.618956754708716	71.365940609877
a3045	loss_cnaOV55	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.83239007329622	4.38947669548849	0.44291337780773	0.40518535300246	0.70559163233974	0.676364135494541	1.09311300254489	0.62771914731901	0.229130211390744	NA	NA	0.0491317539894323	0.0496818589934683	71.365940609877
a3046	loss_cnaOV35	310	YM201636	FYV1	5	27	1.63315443905142	NA	1.89967352123498	2.44159121052756	-0.541917689292581	1.244192866134	0.772812980410438	0.636885021234659	0.435557624579899	0.701227467743581	0.229272849932724	NA	NA	0.644338814441771	0.3936022132895	71.365940609877
a3047	loss_cnaOV82	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	9.88807425464904	8.63637656908716	1.25169768556188	0.896039550729245	1.72444243590475	0.744848324708418	1.39692236190153	0.725856462065757	0.229413460143387	NA	NA	0.920244429547709	0.112626161826897	71.365940609877
a3048	loss_cnaOV21, loss_cnaOV22	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	2.77790303662638	1.40206810539112	1.37583493123526	2.25070864197701	1.86135863432642	0.72802719031518	0.611289664763865	0.739156283943711	0.229459601858788	NA	NA	0.778545690397009	0.401868387379656	71.365940609877
a3049	loss_cnaOV59	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	5.01217448223821	3.73820111687026	1.27397336536795	1.98463174984148	1.63231476019946	0.761851394304141	0.641919270650441	0.780470407075338	0.229472687013862	NA	NA	0.139702411843554	0.294467320909952	71.365940609877
a3050	loss_cnaOV43_(NF1)	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	3.045846900306	2.65495974900693	0.390887151299069	0.785140964621028	0.510596602750536	0.704169107883774	0.497856014286228	0.765549847361688	0.229497349004311	NA	NA	0.128546915772772	0.336189407693142	71.365940609877
a3051	loss_cnaOV33_(ZFHX3)	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.58191247085286	3.80726075474138	0.774651716111477	0.930665561347062	1.06369914121202	0.736668544887373	0.832363147713591	0.728262049012104	0.229498637727357	NA	NA	0.307691573138272	0.197430074501779	71.365940609877
a3052	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	288	KIN001-055	JAK3, MNK1	7	25	2.32630161961136	NA	4.21894764044275	3.68395898162736	0.534988658815395	1.1598051738856	0.974510161385439	0.527456134456278	0.461274592372327	0.548982124573041	0.229555800310763	NA	NA	0.712024528419035	0.295233850835082	71.365940609877
a3053	loss_cnaOV33_(ZFHX3)	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.48819191761288	3.58554770576684	0.902644211846033	1.04307538505723	1.21146266612171	0.754590832030092	0.865368145751528	0.745086280484144	0.229742073103221	NA	NA	0.190228237404932	0.183765318584641	71.365940609877
a3054	RB1_mut	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	1.34159609591976	2.55324403431177	-1.21164793839202	2.32816928292837	1.33655474494063	0.850694135095333	0.52042948391966	0.906545686196966	0.229753576633395	NA	NA	0.231456674896973	0.463642873088644	71.365940609877
a3055	gain_cnaOV4_(KRAS)	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.40692406228167	4.89291087907202	0.514013183209649	0.206209741515315	0.854284789880385	0.630632986619534	2.49267168191215	0.601688323728226	0.229870299135726	NA	NA	0.441686138072753	0.0373336208813611	71.365940609877
a3056	TP53_mut	1020	Lenalidomide	TNFA	21	10	1.6094379124341	NA	4.48617499965105	4.2187995911296	0.267375408521447	0.802307805822568	0.684226119780411	0.348322796458697	0.333257892520839	0.390770537387927	0.229976774115486	NA	NA	0.0393926257545626	0.347845983636768	71.365940609877
a3057	loss_cnaOV41	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.11207396493726	-3.49342716686819	1.38135320193092	2.24001456401546	1.71303980835351	0.778303778962379	0.616671527105922	0.806375424082302	0.230006653211473	NA	NA	0.132085227355624	0.310083212260193	71.365940609877
a3058	loss_cnaOV42	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.11207396493726	-3.49342716686819	1.38135320193092	2.24001456401546	1.71303980835351	0.778303778962379	0.616671527105922	0.806375424082302	0.230006653211473	NA	NA	0.132085227355624	0.310083212260193	71.365940609877
a3059	gain_cnaOV72_(ASXL1)	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.93427905045294	5.6744797803313	0.259799270121639	0.335065170814635	0.489638104366943	0.550465960292461	0.77536936915883	0.530594469271414	0.230209225397423	NA	NA	0.372825130705015	0.182282095154388	71.405443872397
a3060	gain_cnaOV18_(CCNE1)	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.55694969299728	2.5307182203863	1.02623147261097	0.724796532575917	1.75358385084548	0.610213668432381	1.4158890481495	0.585219504682471	0.230301511231285	NA	NA	0.633912642102605	0.0639178075315932	71.4107242832184
a3061	gain_cnaOV49	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	1.77308028272233	2.92440451782352	-1.15132423510119	2.05265569764027	1.49313347345335	0.749854384464661	0.560894959843851	0.7710792474824	0.230429573944554	NA	NA	0.96823771672162	0.435180963886375	71.427091133042
a3062	loss_cnaOV70	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	2.93912202144329	3.73108787824168	-0.79196585679839	0.857119091016329	0.872403028680409	0.909378742260402	0.923985785755065	0.907798151499213	0.230552033710739	NA	NA	0.0532854618614202	0.244184733544346	71.440662336202
a3063	loss_cnaOV20	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	5.08338823632576	4.42914923716957	0.654238999156187	0.875912946541959	0.979056325805442	0.677009325839287	0.746922398782979	0.668234280206466	0.23062394271256	NA	NA	0.316836260466279	0.182231009365822	71.440662336202
a3064	loss_cnaOV35	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.58866828474237	2.68242981997002	0.906238464772349	1.25453889819676	1.57428714678253	0.589702539557374	0.72236776880729	0.575650043655942	0.230843302105425	NA	NA	0.968239088349349	0.199861666109657	71.4480514754388
a3065	loss_cnaOV44	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.54639317581467	2.07220405247287	0.474189123341795	0.636224812070419	0.53899504349411	0.868811012827297	0.745316929402167	0.879765276258941	0.230867298568244	NA	NA	0.0389180644725954	0.324504907920257	71.4480514754388
a3066	loss_cnaOV87, loss_cnaOV88	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.141358355632148	-1.18363648506876	1.32499484070091	0.508445381177715	2.01299597774232	0.679775658626522	2.60597281389757	0.658220312087737	0.230883535652335	NA	NA	0.435059346934133	0.0169157430486474	71.4480514754388
a3067	gain_cnaOV72_(ASXL1)	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	0.430217893806192	-0.154772393293734	0.584990287099926	0.292056636028853	1.01109226053496	0.617535882283836	2.00300289373372	0.578572608982696	0.231081598857044	NA	NA	0.541427473884465	0.0199603935261018	71.4480514754388
a3068	loss_cnaOV81_(RB1)	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.75967040597023	2.2249951405497	0.534675265420528	0.244409142282881	0.935387591210113	0.601321726390246	2.18762383610713	0.571608251429568	0.231120607800487	NA	NA	0.587200186670097	0.0234880405742499	71.4480514754388
a3069	gain_cnaOV51_(MYC)	257	NPK76-II-72-1	PLK3	8	24	2.32630161961136	NA	3.72155348963265	3.06574807930978	0.655805410322869	0.813108946968911	1.30225436710686	0.543786383544652	0.806540639809174	0.503592406282218	0.231174919898634	NA	NA	0.594068797455224	0.109746256937545	71.4480514754388
a3070	loss_cnaOV20	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	5.22855881583443	4.79182408166521	0.436734734169223	0.54099067279237	0.612764864330813	0.72344419217541	0.807286994274742	0.712728094562293	0.231372065430102	NA	NA	0.0457517697298996	0.155190166318375	71.4480514754388
a3071	TP53_mut	211	TL-2-105	CRAF	22	10	2.32630161961136	1.63315443905142	4.31479653855939	4.61672799093834	-0.301931452378954	0.658155340782881	0.522606295265127	0.486509860206863	0.458754086869224	0.577741705590781	0.231372094057668	NA	NA	0.262348982336627	0.177757572108677	71.4480514754388
a3072	loss_cnaOV84	1039	SL 0101-1	RSK, AURKB, PIM3	6	27	2.30258509299405	NA	5.29550370816605	4.85814290255534	0.437360805610705	1.07512464552376	0.744413709201418	0.541976423521064	0.406800092837274	0.587523846222406	0.231389176895633	NA	NA	0.944989938678099	0.379450539344241	71.4480514754388
a3073	loss_cnaOV57_(ZNRF3)	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	2.01439568585641	0.507828122002204	1.50656756385421	2.11698124932803	2.28878463986192	0.663046781802738	0.711658435487995	0.658239109794576	0.231400808969112	NA	NA	0.944814042543685	0.256880015135494	71.4480514754388
a3074	loss_cnaOV1	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.38861909220493	5.761424899864	-0.372805807659073	0.535278387480183	0.603257260715119	0.622416253583508	0.696470876423859	0.6179880988372	0.231639183727897	NA	NA	0.184309510851741	0.351807730987547	71.4653109882276
a3075	TP53_mut	1021	Axitinib	PDGFR, KIT, VEGFR	21	9	0.693147180559945	NA	2.65587399544798	2.2205592103093	0.435314785138678	0.950187493595605	1.19814536992583	0.423804767507751	0.458135671194116	0.363323847060081	0.231766983956883	NA	NA	0.187016032610852	0.351662028705104	71.4653109882276
a3076	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	-0.759498679104364	0.286838017743777	-1.04633669684814	1.57711668785911	1.58957937481441	0.658957724224469	0.663449131508788	0.658247529772023	0.231867976005137	NA	NA	0.453232042232973	0.226249844351331	71.4653109882276
a3077	loss_cnaOV84	1001	AICAR	AAPK1 (AMPK) agonist	6	25	7.60090245954208	NA	8.27559751513124	8.86333809290177	-0.587740577770523	1.07465889875038	1.25082872831749	0.480860832394595	0.546908957301663	0.46988093930422	0.231896736208788	NA	NA	0.521951495602897	0.275826436493527	71.4653109882276
a3078	loss_cnaOV43_(NF1)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	0.348509225697469	-0.454187345343168	0.802696571040637	0.974813804963144	1.43836707136136	0.5786097412932	0.823435785330292	0.558061003357727	0.231924942153932	NA	NA	0.886960125716559	0.159073038747513	71.4653109882276
a3079	PTEN_mut	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.08635245276873	1.6419450394278	0.444407413340935	1.43845661690304	1.49400819586355	0.298186127290377	0.308947387163981	0.297459822892113	0.231954478430638	NA	NA	0.317531595201403	0.653558218621331	71.4653109882276
a3080	loss_cnaOV57_(ZNRF3)	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.75869202563198	2.22514008578499	0.533551939846986	0.991153726913036	0.87672751393348	0.60000368203469	0.538314012609065	0.608572140565293	0.232050670277486	NA	NA	0.587238735940102	0.369601123451638	71.4653109882276
a3081	loss_cnaOV59	310	YM201636	FYV1	4	28	1.63315443905142	NA	1.84151740912767	2.43054502335387	-0.5890276142262	0.722563303000017	0.864497519913659	0.691858903042329	0.815191709543802	0.681352578414602	0.232182916016886	NA	NA	0.644442526081229	0.2062432467752	71.4653109882276
a3082	SMAD4_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.596808878798024	-0.269567949349211	0.866376828147235	1.64748515615767	1.58781216610193	0.543493445314285	0.525878381913821	0.545641888028977	0.232205368225009	NA	NA	0.0943968730160945	0.38159738566606	71.4653109882276
a3083	ARID1A_mut	263	FR-180204	ERK	8	24	2.99573227355399	NA	5.06845251837356	4.72620280899438	0.342249709379184	0.452430405879199	0.804695729854255	0.463939823020949	0.756469293247647	0.425315677319639	0.232209902461057	NA	NA	0.760920080334082	0.149659213054509	71.4653109882276
a3084	TP53_mut	1049	PD-173074	FGFR1, FGFR3	23	10	0.693147180559945	NA	3.1012664410174	2.72256991257141	0.378696528445989	1.05851834007578	0.833083876151697	0.37933089400292	0.357760951424685	0.454571909608093	0.232426517291455	NA	NA	0.0823608645506309	0.282590154571017	71.5087821885661
a3085	loss_cnaOV40	1025	SB 216763	GSK3A, GSK3B	6	17	2.30258509299405	NA	5.35347843980933	4.82106583114291	0.532412608666413	1.17855203363993	0.634355612079202	0.666920623075604	0.451751465755882	0.839296758046083	0.232604755207201	NA	NA	0.441879762687547	0.332119605078388	71.5404219196764
a3086	gain_cnaOV72_(ASXL1)	333	T0901317	LXR	5	27	2.32630161961136	NA	5.11941256359786	4.68556271211502	0.433849851482843	0.501844216256596	1.18362632368555	0.388396073584424	0.864511012439391	0.366542922205321	0.232797426025853	NA	NA	0.00442999391649287	0.196086959074444	71.5764787218696
a3087	TP53_mut	1192	GSK269962A	ROCK1, ROCK2	22	10	1.6094379124341	NA	2.62364883853043	2.03485908351312	0.588789755017312	1.51175614871261	1.2681481390527	0.408032142501156	0.389474026957798	0.464290990055101	0.232908128130288	NA	NA	0.231611331629611	0.265524988436185	71.587318021821
a3088	gain_cnaOV48_(SOX17)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	-0.151144096042164	0.642511538333199	-0.793655634375363	1.16330246045359	1.20093766168143	0.662273722461007	0.682243579254445	0.66086330681325	0.2329956724607	NA	NA	0.422101047987446	0.359537708748905	71.5910347658868
a3089	loss_cnaOV40	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.60810771822211	2.20236651629867	0.405741201923447	0.848946444367757	0.901868596448152	0.455286850444902	0.477934980015869	0.44988948891378	0.233140710596906	NA	NA	0.587283675857959	0.297687419286534	71.6022155634782
a3090	KRAS_mut	1047	Nutlin-3a	MDM2	7	26	2.07944154167984	1.38629436111989	2.99978274144644	3.9490629926341	-0.949280251187661	1.91406556198698	1.41090573696333	0.623978485741132	0.495949705193074	0.67281621040877	0.233182988280804	NA	NA	0.157893644455425	0.255881974330001	71.6022155634782
a3091	gain_cnaOV48_(SOX17)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.26536781482706	2.26334504715089	-0.997977232323831	0.716525320344062	1.30918936452255	0.781393555613964	1.39280106925547	0.76228638833144	0.23335393683714	NA	NA	0.680788960116484	0.113810383036627	71.6164541475104
a3092	loss_cnaOV102	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	4.04227968569761	3.22590617568492	0.816373510012689	0.104755041371911	1.12659376075368	0.749840876329164	7.79316679484975	0.724638763724861	0.233380315805963	NA	NA	0.950007629029424	0.000759327393185317	71.6164541475104
a3093	ARID1A_mut	257	NPK76-II-72-1	PLK3	8	24	2.32630161961136	NA	3.44239207685364	3.15880188356945	0.283590193284189	1.53903169997309	1.12579566407298	0.229692589830718	0.184265335983104	0.251902012358262	0.233636209934619	NA	NA	0.594165568560178	0.641864923780609	71.6354776648389
a3094	SMAD4_mut	1262	UNC1215	LMBL3	4	29	0	NA	3.01113672571809	2.74858870161835	0.262548024099742	0.724008230033184	0.458961725305603	0.534823479003054	0.362631270210435	0.57204775392746	0.233659421758748	NA	NA	0.103702053541381	0.526292129290485	71.6354776648389
a3095	SMAD4_mut	1248	FK866	NAMPT	4	28	0	NA	-0.503240804981794	-1.88051731270236	1.37727650772057	2.16444854542341	2.79709774001893	0.502579888168046	0.636317509433401	0.492394844847736	0.233695787387141	NA	NA	0.0409916679498922	0.309127283423655	71.6354776648389
a3096	loss_cnaOV84	330	XMD13-2	RIPK	6	26	2.32630161961136	NA	4.59409960564942	3.96631202641649	0.627787579232935	1.18270230282763	1.08369625418262	0.570293029479482	0.530807776168192	0.579302158524526	0.233918859170609	NA	NA	0.816326252949729	0.272447270497508	71.6354776648389
a3097	loss_cnaOV52, loss_cnaOV53	282	EKB-569	EGFR	8	24	0.916290731874155	2.99573227355399	1.25254717760716	1.82729525336896	-0.5747480757618	1.87177420906391	1.32969714098975	0.389892174221623	0.307060580800094	0.432239837211343	0.234003242989148	NA	NA	0.317635648768055	0.441362369164679	71.6354776648389
a3098	loss_cnaOV59	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	2.00716203368215	0.508861500884241	1.49830053279791	2.11867849552753	2.28931354952771	0.659223425113939	0.707186359780769	0.65447589436013	0.234058625501408	NA	NA	0.944829697877909	0.259405744822643	71.6354776648389
a3099	loss_cnaOV20	155	AP-24534	ABL	4	15	-0.669430653942629	NA	1.40467613975229	0.624250760989016	0.780425378763277	1.71656865387723	1.09832493009046	0.634381550528655	0.454642683239335	0.710559650775656	0.234083250750508	NA	NA	0.571359174484388	0.440538536411262	71.6354776648389
a3100	loss_cnaOV84	329	QL-XI-92	DDR1	6	26	2.32630161961136	NA	5.05801137147239	4.41267359284823	0.645337778624163	0.840375531646582	1.01964349576291	0.650530473939154	0.767915954620581	0.632905305928825	0.234112788114291	NA	NA	0.183439651748014	0.139463510366492	71.6354776648389
a3101	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.33666277574361	4.86641309783116	0.470249677912454	0.956199303043583	0.782470636746671	0.582719453612971	0.491790442029867	0.600980606592014	0.234121798000808	NA	NA	0.945005437917099	0.346262480657379	71.6354776648389
a3102	loss_cnaOV38	1039	SL 0101-1	RSK, AURKB, PIM3	8	25	2.30258509299405	NA	5.23025955523999	4.84403216704283	0.386227388197159	1.07437455858592	0.711290165895035	0.478198102959764	0.359490445032043	0.542995540661186	0.234845440099538	NA	NA	0.945009505065317	0.365731909489015	71.8230656951606
a3103	gain_cnaOV95_(MECOM)	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.62834037358444	-1.08246703895123	-0.545873334633213	0.893773918857632	1.38604376743005	0.411375096132062	0.610751022284153	0.393835568154785	0.234886273371973	NA	NA	0.0439373594769084	0.355057255943813	71.8230656951606
a3104	loss_cnaOV56	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.79142793389774	2.72398593041755	1.06744200348019	1.11116381898826	1.38798439652263	0.778433500527814	0.9606522325863	0.769059080314226	0.234973660190988	NA	NA	0.621101058700539	0.230335340554864	71.8266391831043
a3105	loss_cnaOV16, loss_cnaOV17	193	GW-2580	CSF1R (cFMS)	6	26	2.99573227355399	NA	6.03744893043452	5.65471099192553	0.382737938508989	0.800233291016331	0.537574290420608	0.649220851478916	0.478282949242084	0.711972178225874	0.235052045474556	NA	NA	0.184464343304168	0.30698397900772	71.8274596702936
a3106	loss_cnaOV20	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.03076189224449	3.75472156566355	-0.723959673419056	1.02164560723769	0.838322685282565	0.833774353624633	0.708621138573175	0.863581155715759	0.235296373182117	NA	NA	0.0534541066542469	0.257599018849461	71.8789721694415
a3107	BRCA1_mut	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.96107850234065	4.37044411146681	0.590634390873842	0.621638177479533	1.03044187336773	0.59168513749632	0.950125671606276	0.573185548975709	0.235551984814625	NA	NA	0.366569316904363	0.160093729123992	71.8998323061053
a3108	loss_cnaOV20	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.77184585251359	4.09058387346374	0.681261979049851	1.15943437062739	0.911155505816159	0.718612848695262	0.587581320951534	0.74769013050041	0.235635688061142	NA	NA	0.0444032079862874	0.268873669245078	71.8998323061053
a3109	loss_cnaOV33_(ZFHX3)	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.86834365390819	3.6859161680956	1.18242748581259	1.34320662871279	1.46365314651894	0.817123777318772	0.880302003084756	0.807860447418708	0.235665210098678	NA	NA	0.062963261034205	0.180625011466487	71.8998323061053
a3110	loss_cnaOV39	1114	Cetuximab	EGFR	9	23	4.18661983833127	NA	6.18745477742826	5.67953100865986	0.5079237687684	0.835625700476991	1.40174909384464	0.39818700380716	0.607836461322895	0.362349989023566	0.235667768671679	NA	NA	0.563900468882502	0.220241813135442	71.8998323061053
a3111	loss_cnaOV41	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	2.00603528749963	1.54196292348606	0.464072364013566	0.789433844115162	0.646118585926324	0.695751462830175	0.587854659985755	0.718246424297231	0.235784745746408	NA	NA	0.200994431756714	0.269619182099709	71.9123978608756
a3112	loss_cnaOV16, loss_cnaOV17	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	2.26379443884116	0.973411375995175	1.29038306284599	2.3434141352032	1.37703353715872	0.847323012826977	0.550642348469959	0.93707453596844	0.235913281008355	NA	NA	0.520763667158134	0.442896968109782	71.9284793588681
a3113	loss_cnaOV70	1248	FK866	NAMPT	3	29	0	NA	0.403955512670807	-1.92687291426227	2.33082842693308	3.20671221063583	2.64978913892741	0.866315932181625	0.726859248298717	0.87962788913708	0.236286326884316	NA	NA	0.0410431581030984	0.334112837147798	72.0190763294034
a3114	gain_cnaOV49	309	Y-39983	ROCK	3	29	2.99573227355399	NA	4.23449703310891	5.03978537859471	-0.805288345485804	1.35174102754791	1.21405797721092	0.658066452900047	0.595741587385724	0.663303038736098	0.236629697119608	NA	NA	0.363986932055148	0.412498459489962	72.0734537616042
a3115	loss_cnaOV16, loss_cnaOV17	330	XMD13-2	RIPK	6	26	2.32630161961136	NA	4.59127944845999	3.96696283192174	0.624316616538253	1.10970429347422	1.09941496547804	0.56697475684702	0.562597279482146	0.567862577954623	0.236675259733241	NA	NA	0.816378665691339	0.251119294941866	72.0734537616042
a3116	gain_cnaOV94	271	VNLG/124	HDAC, RAR 	6	25	1.63315443905142	NA	4.62638275465675	4.25806799343365	0.368314761223101	0.510725723288948	0.58508255491558	0.642837829037042	0.721159605690594	0.62950904642208	0.236768547303071	NA	NA	0.245302259228531	0.159929648785289	72.0734537616042
a3117	loss_cnaOV102	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	3.13449540730035	2.67274694837297	0.461748458927381	0.987718999984748	0.512625043416029	0.82891740455986	0.467489699939468	0.90075283066622	0.236924034663705	NA	NA	0.128837850627614	0.504353618318435	72.0734537616042
a3118	RB1_mut	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	3.80284010846382	4.60081998323284	-0.79797987476902	1.78090466367214	0.884459011302621	0.824625371060015	0.44807557139169	0.902223692190963	0.236955494235408	NA	NA	0.317145823614069	0.52007515517138	72.0734537616042
a3119	gain_cnaOV48_(SOX17)	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	3.73086573677932	4.33453416245728	-0.603668425677965	0.118260432580602	0.91526987421977	0.682294883406002	5.10456804955898	0.659552381960094	0.236957462909442	NA	NA	0.513989055558835	0.00269438942019112	72.0734537616042
a3120	loss_cnaOV20	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.91478157122474	2.17441165805224	0.740369913172501	1.24843543092914	1.41697408533952	0.530754500977719	0.593038209930877	0.522500672971095	0.237085655283532	NA	NA	0.52218708941105	0.278875960779355	72.0734537616042
a3121	loss_cnaOV33_(ZFHX3)	152	CP466722	ATM	4	28	2.77258872223978	NA	2.22743458921042	2.70684269869934	-0.479408109488924	0.875307236986186	0.795796574930755	0.596203465369329	0.547702668539104	0.602425449657959	0.237207590506356	NA	NA	0.548744944044201	0.362432724255558	72.0734537616042
a3122	loss_cnaOV44	293	MP470	PDGFR	3	29	2.99573227355399	NA	5.14880444350694	3.93549496382166	1.21330947968528	1.48529757005509	1.7605511355158	0.695883206219046	0.816879731137161	0.6891645776195	0.23721281840904	NA	NA	0.615870809659884	0.289731291735372	72.0734537616042
a3123	loss_cnaOV40	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	4.25644635541103	3.33026098276564	0.926185372645391	2.02004987876411	1.57430732938249	0.552523291955646	0.458496288820373	0.588312939512694	0.237224337025851	NA	NA	0.693108611834193	0.295047658120566	72.0734537616042
a3124	gain_cnaOV26	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.98856485802196	4.3023034713695	0.686261386652461	0.822192388707836	1.06555831409513	0.652905465297416	0.83467251227051	0.644039258644639	0.237364142153568	NA	NA	0.343203477159108	0.281815749163186	72.0928448449711
a3125	SMAD4_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	3.69983746151682	2.69834574264845	1.00149171886837	1.54253094155035	1.53567165602369	0.651869903324935	0.649252272282981	0.65215224552723	0.237764225556432	NA	NA	0.968261593877398	0.292281881635794	72.1227480299011
a3126	gain_cnaOV95_(MECOM)	1036	PLX4720	BRAF	8	25	2.30258509299405	NA	4.8023419837618	4.14966614492346	0.65267583883834	1.2468786846267	1.30064252389086	0.506461287873275	0.523447747471714	0.501810318246299	0.237842961420102	NA	NA	0.362828445369495	0.225855490045477	72.1227480299011
a3127	SMARCA4_mut	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	0.347623164243977	1.65347636805137	-1.30585320380739	2.54982071467993	1.83856310369197	0.68935668683463	0.51213530280356	0.710257483784563	0.237852839479475	NA	NA	0.778738010060972	0.470698307725732	72.1227480299011
a3128	loss_cnaOV16, loss_cnaOV17	1248	FK866	NAMPT	6	26	0	NA	-0.173411459464818	-2.06257612380017	1.88916466433535	3.32923295529721	2.52283552496674	0.706447526406948	0.567447423986797	0.748825932423897	0.237970709742906	NA	NA	0.0410762949275332	0.236557773145045	72.1227480299011
a3129	loss_cnaOV85	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	7	25	1.63315443905142	NA	3.0290774124744	2.81748050532524	0.21159690714916	0.786524457366445	0.809399367385105	0.26289366684183	0.269027752624069	0.261424601594091	0.238087171486955	NA	NA	0.0175596294673565	0.54608076165323	72.1227480299011
a3130	loss_cnaOV35	152	CP466722	ATM	5	27	2.77258872223978	NA	2.28444516362597	2.71404104082568	-0.429595877199708	0.74427590841817	0.813525612527332	0.533900399977899	0.577199761997859	0.528066812629424	0.238109526915828	NA	NA	0.548782292159591	0.287709021435957	72.1227480299011
a3131	loss_cnaOV41	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.80687311231615	4.32439596683589	0.482477145480259	1.22688231855293	0.777552107809475	0.568288918277075	0.39325462449351	0.620507797013755	0.238112988959525	NA	NA	0.867245622633612	0.437691409091603	72.1227480299011
a3132	loss_cnaOV20	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.31387239235284	0.215351153837777	1.09852123851506	1.41312690434269	1.67115143694451	0.667252305931259	0.777369134462863	0.657343921220911	0.238136107729109	NA	NA	0.834181456791168	0.224480557215533	72.1227480299011
a3133	loss_cnaOV1	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	4.24053622089386	2.41620396114746	1.8243322597464	2.6824923158812	2.25790830238113	0.797116075438336	0.680088531454788	0.807974468149351	0.238146708944333	NA	NA	0.377486748765051	0.359936757828997	72.1227480299011
a3134	gain_cnaOV72_(ASXL1)	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	2.86270059298559	1.8899033834418	0.972797209543795	0.876490079640337	2.08872561417691	0.493640188722452	1.10987817448313	0.465737195417665	0.238254321454361	NA	NA	0.125803196090006	0.104530355243785	72.1323150854261
a3135	loss_cnaOV34	1020	Lenalidomide	TNFA	5	26	1.6094379124341	NA	4.17443193901675	4.44328889264939	-0.268856953632645	1.08318290308438	0.709237948377872	0.348410854024236	0.248210115638893	0.37907863538261	0.238356756385922	NA	NA	0.0395611293500899	0.618052432756487	72.1403090078914
a3136	gain_cnaOV19	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.90103518266913	3.63236704835348	1.26866813431565	0.692564428625792	1.56876026194597	0.830565742455778	1.83184131595235	0.808707464798945	0.238502560554866	NA	NA	0.158111112800091	0.0547397636681997	72.1614196440966
a3137	gain_cnaOV72_(ASXL1)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	2.84402439954556	3.62974842758413	-0.785724028038572	0.733006676682999	1.13434221467326	0.731268658376325	1.07191933311458	0.692669300211924	0.238783964913445	NA	NA	0.765613998002059	0.135526860949377	72.2027247393044
a3138	gain_cnaOV72_(ASXL1)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	1.47884314340441	0.75636552223462	0.72247762116979	0.804494842102034	1.27974189159254	0.588788942938737	0.898051278094035	0.564549481357311	0.238904719966957	NA	NA	0.84211678201425	0.134535188435108	72.2027247393044
a3139	loss_cnaOV41	293	MP470	PDGFR	5	27	2.99573227355399	NA	4.8477524422192	3.90137055815752	0.94638188406168	1.13876473180574	1.82120053416169	0.542124263064358	0.831060057998989	0.519647269100602	0.238943839481392	NA	NA	0.615934087454975	0.162577755303746	72.2027247393044
a3140	loss_cnaOV83	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	2.59821817084265	1.6640721114289	0.934146059413745	1.62104865372063	1.64312261716606	0.569862276578935	0.576260346825304	0.568518776173193	0.238968549758274	NA	NA	0.330346482519913	0.35596009963695	72.2027247393044
a3141	loss_cnaOV59	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.11171917149177	4.45164025256153	-0.33992108106976	0.997372340620633	0.570661393386074	0.542528785210212	0.340816631087081	0.595661604253279	0.239019562310982	NA	NA	0.26272599273736	0.549070543502232	72.2027247393044
a3142	gain_cnaOV19	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	7.52089971752501	6.54328090021829	0.977618817306719	2.64064633580087	1.25729188262446	0.656850776533506	0.370219519385288	0.777559157755831	0.239228718627742	NA	NA	0.321467016862814	0.589617067164371	72.2429064426759
a3143	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	7	25	1.63315443905142	NA	3.17475158201361	2.77669173785426	0.398059844159354	0.928040353350094	0.754032170043228	0.502665170678277	0.428925146112898	0.527908304146405	0.239391580033038	NA	NA	0.0175734990912884	0.326389645469809	72.2636565692961
a3144	loss_cnaOV20	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	2.50469708758504	1.3913243645787	1.11337272300633	0.594351491884441	1.68158889494586	0.704467426655529	1.87325637810093	0.662095668181837	0.2394497533451	NA	NA	0.0738317264078269	0.0157856373171391	72.2636565692961
a3145	ARID1A_mut	1054	PD-0332991	CDK4, CDK6	9	24	1.38629436111989	0.693147180559945	1.29646704353191	2.65454044959405	-1.35807340606215	1.34875692360943	1.79849726247478	0.8017409685449	1.00690745848242	0.755115637036555	0.239661673694687	NA	NA	0.10471793062172	0.0302148639164647	72.2851923146744
a3146	PIK3R1_mut	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.99258781707051	-1.37754928430017	0.38496146722966	2.08589091940957	1.84836553957864	0.204574279787862	0.184554937004389	0.208271285623199	0.239692306942643	NA	NA	0.0693232516054142	0.714983258353353	72.2851923146744
a3147	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1133	JNJ-26854165	MDM2	8	25	2.30258509299405	NA	3.41337015250357	2.9572922172468	0.456077935256776	0.795533067112106	0.933201077378828	0.504539310849933	0.573298526624922	0.488724184221696	0.239749663948013	NA	NA	0.230970010283833	0.198479445128071	72.2851923146744
a3148	loss_cnaOV1	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	4.92114483483988	4.12212273591618	0.7990220989237	0.146270657844339	0.984557984072803	0.839376939483615	5.46262736969447	0.811554130736313	0.239916459274059	NA	NA	0.0444917162138483	0.000532964849407059	72.311059717343
a3149	loss_cnaOV35	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.76764984574292	1.69068780109846	1.07696204464446	1.67688849466665	1.63060199378351	0.658243314633482	0.642238317019732	0.660468985534335	0.239987880496766	NA	NA	0.330437252335967	0.386570314839837	72.311059717343
a3150	loss_cnaOV57_(ZNRF3)	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	3.07770400729878	2.66436898912579	0.413335018172992	0.784771178084161	0.525048609315396	0.742737054676507	0.526694952256088	0.787231907369364	0.24020111443594	NA	NA	0.128962832748276	0.374319974543686	72.3118422785927
a3151	TP53_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	23	10	2.30258509299405	NA	2.89656665659544	2.09975940614968	0.796807250445762	1.63375064998343	1.77116952265344	0.475760239928098	0.487716562165619	0.449876333267095	0.240225332695554	NA	NA	0.634254522626402	0.241824294494708	72.3118422785927
a3152	gain_cnaOV48_(SOX17)	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	2.48634707455749	3.03652620151473	-0.550179126957232	0.590999151109726	1.0233790640561	0.54955549999917	0.930930485981502	0.537610301286241	0.240347121147072	NA	NA	0.0825950905983798	0.242943558507306	72.3118422785927
a3153	loss_cnaOV34	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	1.00874119236505	0.571533407488592	0.437207784876459	0.735952008688269	0.576662025176566	0.72825771778089	0.594071053159731	0.75816989118122	0.240491846013743	NA	NA	0.0135341403620514	0.264205420775735	72.3118422785927
a3154	gain_cnaOV95_(MECOM)	1069	EHT 1864	Rac GTPases	8	25	2.30258509299405	NA	4.59649589667313	4.11182960455025	0.484666292122882	0.780661865922895	1.00968334081996	0.503422429729851	0.620840229655527	0.480018113133653	0.240613723981094	NA	NA	0.201989760364675	0.176562339591791	72.3118422785927
a3155	gain_cnaOV72_(ASXL1)	293	MP470	PDGFR	5	27	2.99573227355399	NA	3.22255440359472	4.20233315790279	-0.979778754308065	2.46404332759044	1.60367097818321	0.562090166625265	0.397630489422513	0.610959958518454	0.240680535148288	NA	NA	0.615997007517369	0.43380727967501	72.3118422785927
a3156	loss_cnaOV59	1028	VX-702	p38	4	27	0.693147180559945	NA	3.8822694441026	3.24470252200956	0.637566922093043	0.803847895953256	0.918188298450611	0.702918178489597	0.793143734408826	0.69437491543826	0.240731374289947	NA	NA	0.510383300171018	0.215999575137873	72.3118422785927
a3157	loss_cnaOV81_(RB1)	1026	17-AAG	HSP90	4	29	0	NA	0.986091323468286	-0.740062983360164	1.72615430682845	1.71214567487615	2.29091294744497	0.770108105130096	1.00818191591864	0.753478786155367	0.240775559720839	NA	NA	0.0571708197444112	0.135394418367669	72.3118422785927
a3158	loss_cnaOV57_(ZNRF3)	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.03577960281283	3.75360651887059	-0.717826916057753	1.01763257662247	0.840197198414223	0.825919197503647	0.705389088899083	0.854355283988771	0.240779852720058	NA	NA	0.0536443889851841	0.25954826164224	72.3118422785927
a3159	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	7	25	2.32630161961136	NA	5.33914642952048	5.08736108245496	0.25178534706552	0.77528157061442	0.522293591880173	0.432799292746097	0.324766325692454	0.482076270855886	0.24091698784214	NA	NA	0.0105925379960495	0.442933119507918	72.3118422785927
a3160	NF1_mut	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-2.97315053673524	-1.88953682487715	-1.08361371185809	1.61082229909184	1.51860606901441	0.708983955303961	0.67270841263435	0.713558133322463	0.240968947318516	NA	NA	0.0346673186176636	0.27737461306592	72.3118422785927
a3161	loss_cnaOV39	1038	NU-7441	PRKDC (DNAPK)	10	23	0.693147180559945	NA	2.91372409557763	2.37327090194094	0.540453193636684	1.18697272997135	0.930585759485916	0.53418389699005	0.4553206488996	0.580766671021537	0.241012394197452	NA	NA	0.38710069373499	0.221611540534063	72.3118422785927
a3162	loss_cnaOV87, loss_cnaOV88	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.74552784179545	5.23686192256115	-0.491334080765705	1.04920274305402	0.738892651824053	0.643516981276171	0.468292790900954	0.664960031139547	0.241051741423137	NA	NA	0.325159439395546	0.504897352251233	72.3118422785927
a3163	loss_cnaOV38	205	BMS-708163	g-secretase	8	24	2.32630161961136	0.940007258491471	5.33965725359958	4.96945369438546	0.37020355921412	0.635722060367781	0.589028829711168	0.616750093828513	0.582335555572741	0.628498199987341	0.241329224131708	NA	NA	0.104610731214185	0.17360617086396	72.3118422785927
a3164	loss_cnaOV40	1030	KU-55933	ATM	8	25	2.30258509299405	NA	4.56551831111483	4.01834720353578	0.547171107579047	0.910705114934261	1.03672380251086	0.541944720305459	0.600821384009185	0.527788699607209	0.2414246085276	NA	NA	0.52264864427999	0.17606737956115	72.3118422785927
a3165	loss_cnaOV54	1259	BMN-673	PARP1	11	22	2.30258509299405	NA	2.47288247375042	1.61416663670807	0.858715837042342	0.782722764108612	1.51875201970515	0.647249915535282	1.09708810886607	0.565408852729661	0.241454881627242	NA	NA	0.0314922441645414	0.0400800405027681	72.3118422785927
a3166	PTEN_mut	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	3.63870212552716	4.51269860747627	-0.873996481949108	1.0629136728339	0.665673423579566	1.21888435892539	0.82226478432523	1.31295084194486	0.241524680733623	NA	NA	0.0396230919526721	0.198492780325198	72.3118422785927
a3167	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.895456898525882	-0.313812100420005	1.20926899894589	1.83656063086149	1.53289622119086	0.771689450411885	0.65844218732852	0.788878583056618	0.241527799850396	NA	NA	0.094714066803033	0.284281419537946	72.3118422785927
a3168	loss_cnaOV21, loss_cnaOV22	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.47853891685095	4.67889568018317	0.799643236667783	0.334786077355786	1.25493429786352	0.658643857752525	2.38851998560855	0.63719928447979	0.241530463346491	NA	NA	0.416439493028575	0.0245107281955283	72.3118422785927
a3169	loss_cnaOV16, loss_cnaOV17	1170	CCT018159	HSP90	6	27	2.30258509299405	NA	4.32742180813411	3.55441186255131	0.773009945582809	1.27628514258775	1.17904946070532	0.646725325418196	0.60567182033905	0.655621304572231	0.241938787100058	NA	NA	0.190762522590586	0.215784164642499	72.3118422785927
a3170	loss_cnaOV56	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.58879294713624	3.60557574320937	0.983217203926867	1.29462044036534	1.1924104007128	0.819848119960624	0.75946368006472	0.824562754014156	0.241969589412923	NA	NA	0.190763830881082	0.31730608203301	72.3118422785927
a3171	MLL2_mut	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	5.57091241252122	5.84839892960233	-0.27748651708111	0.319509337937581	1.33723210496072	0.214354705275655	0.868477018143739	0.207508117739412	0.242189835667145	NA	NA	0.564162237509769	0.386249726935347	72.3118422785927
a3172	loss_cnaOV1	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.39853550168054	3.78566020146351	0.612875300217034	0.316992941863673	0.877495385432623	0.718891828442701	1.93340361654049	0.698437063477973	0.24221646587803	NA	NA	0.922438161477313	0.0453255428749036	72.3118422785927
a3173	gain_cnaOV18_(CCNE1)	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.47739330470608	4.67901842434155	0.798374880364535	1.05181114921588	1.22532330816846	0.657556906364239	0.759047744416593	0.651562632525042	0.242229645655008	NA	NA	0.416473543634896	0.31813059096774	72.3118422785927
a3174	loss_cnaOV41	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.30588109687833	0.216535049463631	1.08934604741469	1.35792061161412	1.67722640336773	0.661385041966969	0.802216299021945	0.649492546281994	0.242302380121028	NA	NA	0.834253989916177	0.21347811663118	72.3118422785927
a3175	loss_cnaOV42	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.30588109687833	0.216535049463631	1.08934604741469	1.35792061161412	1.67722640336773	0.661385041966969	0.802216299021945	0.649492546281994	0.242302380121028	NA	NA	0.834253989916177	0.21347811663118	72.3118422785927
a3176	loss_cnaOV44	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	5.23444251383851	4.45765974269537	0.776782771143141	0.960602156083195	0.969794358735241	0.801464723430119	0.808641502857366	0.800976788683514	0.242450258217615	NA	NA	0.317406464827071	0.293502603535267	72.3118422785927
a3177	loss_cnaOV42	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.31856072473812	2.20947384555376	1.10908687918437	2.4590005623889	1.38270467004901	0.729407491481451	0.451031567925669	0.80211407627997	0.242466167113671	NA	NA	0.234352000142123	0.437388445434375	72.3118422785927
a3178	loss_cnaOV59	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.80898293969389	4.20207700581513	0.606905933878761	1.28131090655819	0.822381625350219	0.690354326158685	0.473660163799751	0.737985766182829	0.24260647139614	NA	NA	0.514232392883072	0.418434003950907	72.3118422785927
a3179	loss_cnaOV41	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.41426075130644	4.99677196064872	0.417488790657719	0.560613241536732	0.608870395350915	0.692744166197299	0.744700195652381	0.685677598788663	0.242617752001174	NA	NA	0.104654301246489	0.183006075521993	72.3118422785927
a3180	loss_cnaOV41	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	3.84029949714741	2.35518615000819	1.48511334713923	2.15625566132625	2.3062271205583	0.649428820804669	0.688746410630071	0.643957975301106	0.242781972343437	NA	NA	0.377710932119532	0.212665877557293	72.3118422785927
a3181	gain_cnaOV26	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.41027598913907	5.90091708424102	0.509358904898042	0.439301613822231	0.706082546118857	0.73608731585063	1.15947424018379	0.721387191480443	0.243054513157778	NA	NA	0.907143401326856	0.166881944290133	72.3118422785927
a3182	ARID1A_mut	1018	ABT-888	PARP1, PARP2	9	22	1.6094379124341	NA	3.91908911561914	4.45524220946195	-0.536153093842809	0.709370835933005	0.789090213042675	0.698183553785485	0.755814965437125	0.679457285087139	0.243102046659768	NA	NA	0.216926140364505	0.0826389406408132	72.3118422785927
a3183	gain_cnaOV48_(SOX17)	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	-0.700395684663137	0.470398492036456	-1.17079417669959	3.16193270512573	1.47944451677807	0.708945963003532	0.370278018504837	0.791374170117134	0.24314173003749	NA	NA	0.83426841542824	0.588366910711556	72.3118422785927
a3184	KRAS_mut	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	4.33170372576429	3.66929350294965	0.662410222814636	0.791551767223445	0.980293623800965	0.690921037989171	0.836850159703636	0.675726340283867	0.243190877829394	NA	NA	0.801312852386098	0.285325063540988	72.3118422785927
a3185	loss_cnaOV83	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.1990028915725	2.56856327786678	-0.369560386294287	0.579982644094555	0.625114382260038	0.596751517862512	0.637192147139556	0.591188423722037	0.24326934188143	NA	NA	0.855623217141303	0.244756842200259	72.3118422785927
a3186	TP53_mut	1018	ABT-888	PARP1, PARP2	21	10	1.6094379124341	NA	4.40018515837547	4.08832423228503	0.31186092609045	0.819318021169864	0.734328302421597	0.39281342843936	0.380634769445397	0.424688691777268	0.243287777540047	NA	NA	0.216934866548956	0.300134505917855	72.3118422785927
a3187	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	0.980327238683547	-0.0428441110499989	1.02317134973355	1.81368364330465	1.20250158739137	0.793445756690989	0.56413992236775	0.850869022096799	0.243336943746551	NA	NA	0.865651400925571	0.43410625671097	72.3118422785927
a3188	loss_cnaOV41	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	-0.740683977523491	0.283219805901301	-1.02390378342479	1.59273797526456	1.58953767696352	0.643972954402611	0.642857644713793	0.644151943212035	0.243423682603025	NA	NA	0.453790313633802	0.23880045217025	72.3118422785927
a3189	gain_cnaOV49	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	3.87185766833568	4.34541277299029	-0.473555104654616	0.578348248675572	0.808771168223081	0.595646648884637	0.818806153107692	0.58552421656554	0.243560205706856	NA	NA	0.216947651522108	0.289958830912602	72.3118422785927
a3190	loss_cnaOV36	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.89060469873421	3.63341009674697	1.25719460198724	1.15724066779183	1.55063024990457	0.822604970617613	1.0863726422492	0.810763624703316	0.243592121563765	NA	NA	0.158313846000918	0.188918724611602	72.3118422785927
a3191	loss_cnaOV21, loss_cnaOV22	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	4.95606981002183	3.77020864843661	1.18586116158522	2.20682070722506	1.5040064305663	0.758874573156601	0.537361806377269	0.788468145803546	0.243725243924623	NA	NA	0.71064170463499	0.451828227124515	72.3118422785927
a3192	SMAD4_mut	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-0.693485221871055	-1.73704350065743	1.04355827878637	2.10192999297559	1.11009550003719	0.823177839058858	0.496476230071327	0.940061714286212	0.243837039408386	NA	NA	0.61072276048153	0.482632875246174	72.3118422785927
a3193	loss_cnaOV35	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-3.44164234414905	-4.32081548905434	0.879173144905285	2.54635388047855	0.990577676986644	0.671352652452213	0.345267463271859	0.887535793840769	0.24384014987107	NA	NA	0.209936044826548	0.486666943472092	72.3118422785927
a3194	loss_cnaOV20	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	4.40641044403162	3.37266676361902	1.0337436804126	1.25685857309931	1.73593236992889	0.616055256142086	0.822482101437612	0.595497669333133	0.243937488595575	NA	NA	0.693316135019137	0.157856077211597	72.3118422785927
a3195	gain_cnaOV94	286	KIN001-236	TIE2	7	25	2.32630161961136	NA	5.06739535064209	4.71881979589766	0.348575554744428	0.622287887593939	0.66041127949811	0.533835226955442	0.560151598148869	0.527815871057403	0.243954041235244	NA	NA	0.758038276050985	0.224986557267852	72.3118422785927
a3196	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.8885958039492	2.30706744921513	0.581528354734068	1.05795350336571	0.844332920895627	0.676017891177499	0.549672885324382	0.688742959491869	0.243961219272942	NA	NA	0.601640892280194	0.443617106309519	72.3118422785927
a3197	PTEN_mut	1026	17-AAG	HSP90	4	29	0	NA	-2.72520586889885	-0.228159922344007	-2.49704594655485	1.44182135946203	2.22056660838137	1.15736650660328	1.73186915991211	1.12450846424959	0.244094548690511	NA	NA	0.0572472260290709	0.0282675318510729	72.3118422785927
a3198	loss_cnaOV81_(RB1)	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.75241628160701	0.833538196677452	0.918878084929561	0.23929111172028	1.29402801452047	0.7359293472088	3.84000090234728	0.710091338532631	0.244118736649555	NA	NA	0.956668102971362	0.00424625059870432	72.3118422785927
a3199	RB1_mut	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-2.77296851754437	-3.78954641184509	1.01657789430072	1.13386315755928	1.75109815949107	0.592523860111481	0.896561359740248	0.580537355253788	0.24427724429936	NA	NA	0.236888253399861	0.256094977612961	72.3118422785927
a3200	SMARCA4_mut	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	3.95179221475213	4.54352157837045	-0.591729363618328	0.566140815581637	0.691044197875313	0.865512815397718	1.04519820393165	0.856282948959938	0.244300805924677	NA	NA	0.0766631822300793	0.20224057893411	72.3118422785927
a3201	loss_cnaOV58	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-0.187780676741018	-0.839073087788249	0.651292411047231	1.46102694353921	0.782668717534611	0.72412271025088	0.445777139105683	0.832143148762592	0.244368926568227	NA	NA	0.0388011443378308	0.381117629123983	72.3118422785927
a3202	loss_cnaOV55	219	AT-7519	CDK9	7	25	2.32630161961136	NA	0.96155524540574	1.64783039504447	-0.686275149638732	1.43184920982754	1.75293782252892	0.405217473136208	0.479292892665275	0.391499995503925	0.244372773170745	NA	NA	0.30783356121329	0.308884262433756	72.3118422785927
a3203	loss_cnaOV34	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-1.83433489160391	-2.89845112794657	1.06411623634266	1.92694561979664	1.7071619886464	0.612239097539353	0.552229510480407	0.623324701123643	0.244543370315387	NA	NA	0.691220886798966	0.298560764253312	72.3118422785927
a3204	loss_cnaOV56	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.84419626602913	3.87593377210919	0.968262493919939	0.866267301453496	1.15714396602876	0.849748215727873	1.11774101630675	0.836769254601011	0.24461430044541	NA	NA	0.0776959944890303	0.179674542745079	72.3118422785927
a3205	loss_cnaOV44	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	2.20570218440095	0.539988400216707	1.66571378418424	0.983229395273628	2.34027209400021	0.732141362358782	1.69412528977602	0.711760734341384	0.244722227343689	NA	NA	0.944890369081123	0.0681580528268619	72.3118422785927
a3206	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.40299035455941	-3.65403739338585	1.25104703882644	2.14114125320076	1.6633734655684	0.724632415958824	0.584289820653478	0.752114341561251	0.244724618745971	NA	NA	0.671630956142266	0.421555964758308	72.3118422785927
a3207	loss_cnaOV44	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	3.13844084914424	2.20333172921605	0.935109119928191	1.82970069598774	1.35623944424589	0.670779205847929	0.511072178077401	0.689486745054921	0.244767875701566	NA	NA	0.522524188764934	0.471743266124853	72.3118422785927
a3208	loss_cnaOV20	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.32188550094728	3.75500273833214	0.56688276261514	1.08801884916851	0.821660053725203	0.655545976349016	0.5210229244175	0.689923722158616	0.244782309384549	NA	NA	0.938316830370844	0.383930915769636	72.3118422785927
a3209	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	263	FR-180204	ERK	7	25	2.99573227355399	NA	5.11011892445611	4.72822620366643	0.381892720789679	0.596290212387181	0.766431837480744	0.519187274541951	0.640447743156498	0.498273560823045	0.244867793843333	NA	NA	0.761223998558269	0.186135918667247	72.3118422785927
a3210	loss_cnaOV21, loss_cnaOV22	1248	FK866	NAMPT	3	29	0	NA	0.374046553983275	-1.92377888405321	2.29782543803649	2.10015390045893	2.73050713307665	0.853233981561132	1.09412240576005	0.841537973001876	0.244871285864558	NA	NA	0.0412093151416567	0.186821537211506	72.3118422785927
a3211	gain_cnaOV19	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	0.511700711985426	-0.122857492615729	0.634558204601154	0.0376232981978152	0.986829782430429	0.665561640215996	16.8660972056406	0.64302701022898	0.244885737204014	NA	NA	0.542004586319603	0.00180618556923986	72.3118422785927
a3212	loss_cnaOV57_(ZNRF3)	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-1.12102894617851	-0.770161913302215	-0.350867032876297	0.842519786237471	0.7997636140822	0.436243304239853	0.416449605822554	0.438713423189361	0.244956748076379	NA	NA	0.0737582387108249	0.47937875492485	72.3118422785927
a3213	gain_cnaOV96	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.33949840476731	5.89311540950271	0.446382995264599	0.975272121347465	0.654590631214418	0.644923728812997	0.457700969292409	0.681926954005519	0.245000051217323	NA	NA	0.907160935656321	0.433039170738177	72.3118422785927
a3214	gain_cnaOV94	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	3.01362444417591	2.33890239340539	0.674722050770515	0.620149265332298	0.844940699914148	0.821136692928537	1.08799943576322	0.798543673939569	0.245028533331641	NA	NA	0.610691402839213	0.188234998468427	72.3118422785927
a3215	loss_cnaOV55	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	4.53991028632984	3.69394498258257	0.845965303747278	1.68277714232964	1.52880692829001	0.541622788619472	0.502719749672926	0.553349993444562	0.245085757773986	NA	NA	0.710680861761639	0.262644260059402	72.3118422785927
a3216	gain_cnaOV50	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	4.00366294898841	3.5630024686293	0.440660480359116	0.400794477273117	0.941911103977096	0.488256195853293	1.09946744615154	0.467836591477142	0.245169498180525	NA	NA	0.0537932649828893	0.209991133357268	72.3118422785927
a3217	loss_cnaOV39	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-1.95926629825196	-2.45723735457288	0.497971056320923	0.679303657275876	0.745061667716555	0.682037955753349	0.733061055961147	0.668362201275353	0.245194191820997	NA	NA	0.664399733966131	0.208849307400973	72.3118422785927
a3218	gain_cnaOV72_(ASXL1)	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.39116716691182	3.81365628344116	0.577510883470668	0.924652350297598	1.08104397084309	0.543714095421691	0.62457082738696	0.534215905223798	0.245357135825156	NA	NA	0.308452096006133	0.256136861994965	72.3118422785927
a3219	loss_cnaOV42	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	2.33899546315739	2.9387347381365	-0.599739274979112	0.656578163576197	0.796460788458959	0.765366962855759	0.913431649496993	0.75300540047869	0.245371646993129	NA	NA	0.0176360301204258	0.166016204718266	72.3118422785927
a3220	gain_cnaOV95_(MECOM)	1059	AZD8055	MTORC1/2	8	25	0.693147180559945	NA	0.703715985910889	0.145894662618114	0.557821323292774	1.48101303598336	0.992051787104411	0.49749599239779	0.376648489742963	0.562290528119441	0.245401504647825	NA	NA	0.140343965947288	0.344903075602729	72.3118422785927
a3221	gain_cnaOV4_(KRAS)	167	OSU-03012	PDPK1 (PDK1)	6	13	2.77258872223978	NA	2.74703665655002	2.11273907741147	0.634297579138551	1.6371598981412	0.971546216576897	0.525920979865203	0.387437769431514	0.65287432374901	0.24554429924511	NA	NA	0.374360781931872	0.409288390572341	72.3314560172356
a3222	loss_cnaOV40	344	THZ-2-49	CDK9	7	25	2.99573227355399	NA	1.83028219634876	2.79918192646067	-0.968899730111912	2.60588863140515	2.23895832625952	0.418170335212641	0.371811641693015	0.432745763397297	0.245676669872155	NA	NA	0.377848296254418	0.394764164372658	72.3468127610136
a3223	loss_cnaOV84	1024	CEP-701	FLT3, JAK2, NTRK1, RET	6	25	0.693147180559945	NA	0.70273982220274	-0.364301522018121	1.06704134422086	1.44966189522836	1.58496369418412	0.682918735993474	0.736062214046657	0.673227625425284	0.245748927940719	NA	NA	0.094853016479143	0.149992613207453	72.3468127610136
a3224	loss_cnaOV40	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	4.25749373688323	3.74139585264909	0.516097884234139	1.24971624728939	0.746602195024142	0.59644588829302	0.412972052938853	0.691262211220061	0.245858418103366	NA	NA	0.938326536255949	0.420157250443101	72.3565958438488
a3225	NF1_mut	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	4.68088467308703	3.9987561295849	0.68212854350213	0.621137115288445	1.14647935911938	0.61717707828684	1.09819317943247	0.594976732966287	0.246045770593831	NA	NA	0.816551350491957	0.11820329245116	72.3695280920304
a3226	loss_cnaOV20	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	5.03520863114901	4.50570174146666	0.529506889682355	0.898777106198951	0.936227301294999	0.568554681617433	0.589141496851996	0.565575142863208	0.246078488618497	NA	NA	0.942153396040589	0.276607309765898	72.3695280920304
a3227	loss_cnaOV83	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	4.40258613119385	3.37340220839551	1.02918392279834	1.25875283969703	1.73616721858313	0.61318979418999	0.817621927308663	0.592790781776335	0.246198928907809	NA	NA	0.69338445447091	0.15992566933782	72.3695280920304
a3228	loss_cnaOV39	1053	MK-2206	AKT1, AKT2	10	22	1.38629436111989	0.693147180559945	1.80943063689461	1.08282837137226	0.726602265522351	1.15670179641716	1.18646481574064	0.617011781634752	0.628167318294981	0.612409450227799	0.246242966788555	NA	NA	0.0920854697642687	0.11975148825454	72.3695280920304
a3229	gain_cnaOV72_(ASXL1)	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.52807034669616	5.12834176096959	0.399728585726567	0.379376716453058	0.806109812223904	0.523804074522754	1.05364554120186	0.495873613824141	0.246283722442661	NA	NA	0.32541116577825	0.107280273961361	72.3695280920304
a3230	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.91307142807975	4.32390315524626	0.589168272833491	0.665427673833607	0.760415588385125	0.784358682745463	0.885397911750834	0.774797731441424	0.246449403095647	NA	NA	0.0397176039284518	0.176082076178981	72.3872350660361
a3231	gain_cnaOV96	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	3.67027234324492	2.7024236899963	0.967848653248621	1.62432315718429	1.52933075077338	0.628971479436278	0.595847352768371	0.632857642311308	0.246496563987681	NA	NA	0.968288859820871	0.327064956413466	72.3872350660361
a3232	loss_cnaOV36	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	4.0832115129808	3.42164707500368	0.661564437977118	1.53418611003241	0.828583162499877	0.742389562490331	0.431215244129111	0.798428531882237	0.246823544465127	NA	NA	0.790853528532391	0.534487946148696	72.4343144531432
a3233	loss_cnaOV81_(RB1)	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.46454385478015	5.7306475277468	0.733896327033344	0.343593721620961	1.33671157032926	0.576616988911238	2.13594219234003	0.549031177198961	0.246840001098608	NA	NA	0.564343624470402	0.026259030555719	72.4343144531432
a3234	loss_cnaOV43_(NF1)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.56324971274806	2.68696885068329	0.876280862064766	1.77870776873806	1.50040824216768	0.569328510919054	0.49265026974412	0.584028291392735	0.246909103435549	NA	NA	0.968290118138809	0.346375843721036	72.4343144531432
a3235	gain_cnaOV18_(CCNE1)	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-1.90490367756614	-2.43853598300104	0.533632305434897	0.802804509781256	0.714302253333846	0.73030323619537	0.664710149149883	0.747067929499435	0.246962243924464	NA	NA	0.664501385938056	0.288473608680345	72.4343144531432
a3236	loss_cnaOV20	305	TPCA-1	IKK	5	27	2.99573227355399	NA	2.73435666269884	3.4346095204588	-0.700252857759954	1.18343377959492	1.21700076916837	0.577490570815285	0.59171275134604	0.5753922885673	0.247088645911563	NA	NA	0.993501024143723	0.274188495170735	72.448992942491
a3237	loss_cnaOV40	155	AP-24534	ABL	4	15	-0.669430653942629	NA	1.38702028364017	0.628958989285581	0.758061294354592	1.19032123729367	1.24172490088539	0.614905500850036	0.636854380652847	0.610490531207089	0.24716627988092	NA	NA	0.57229890059146	0.314010684175066	72.4493674837464
a3238	loss_cnaOV83	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-1.37014322106571	-2.85905785756114	1.48891463649543	3.08020158641203	1.56899497425428	0.77388157789592	0.483382205587975	0.948960742976938	0.247548662235074	NA	NA	0.330324726371528	0.410902212886709	72.5174364177963
a3239	SMARCA4_mut	304	SB52334	ALK5	3	29	2.99573227355399	NA	3.81336956890128	4.42387539783026	-0.610505828928974	2.05431780281642	0.944348730276372	0.57850580347306	0.297181783700646	0.646483453999355	0.247723762986543	NA	NA	0.343704126623992	0.659338302535571	72.5174364177963
a3240	gain_cnaOV18_(CCNE1)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	3.14042737061653	2.82424446564234	0.316182904974187	1.06918209571932	0.76739777572574	0.393900090375039	0.29572409250032	0.412019574431484	0.247767646935195	NA	NA	0.0176606101140473	0.603162353218136	72.5174364177963
a3241	loss_cnaOV57_(ZNRF3)	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	3.08076588382915	2.20442759543906	0.876338288390091	0.778982232078801	1.47954044250943	0.614945126481881	1.12497853263159	0.592304382639077	0.247785334734105	NA	NA	0.817913973722591	0.112261575045229	72.5174364177963
a3242	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.83276557756894	2.85744578758557	0.975319789983361	0.88886237258214	1.67712104850774	0.611603310131693	1.09726749614798	0.581544063769981	0.247830930702701	NA	NA	0.658040540703613	0.0850289772413775	72.5174364177963
a3243	loss_cnaOV40	291	KIN001-266	MAP3K8 (COT)	7	25	2.99573227355399	NA	2.87911686941812	3.42097200264114	-0.541855133223021	0.90729421704364	1.13334164735395	0.496257774366824	0.597220970931152	0.478103963167776	0.247899859335858	NA	NA	0.950082033919971	0.212413502053278	72.5174364177963
a3244	gain_cnaOV48_(SOX17)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	-0.0211221483652969	1.11024325479876	-1.13136540316406	0.797728756506666	1.56350309511273	0.742138723196401	1.41823319510058	0.723609314686062	0.247933500299155	NA	NA	0.787497746053549	0.10874934861854	72.5174364177963
a3245	loss_cnaOV38	1053	MK-2206	AKT1, AKT2	8	24	1.38629436111989	0.693147180559945	1.87067947350624	1.12296228129525	0.747717192210991	1.05270750165173	1.218001389933	0.632852545161973	0.710280102533517	0.613888619825074	0.248147504242677	NA	NA	0.0921440858276123	0.117320314864853	72.5545322776079
a3246	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	1.59620511520506	2.40250767729791	-0.806302562092853	1.18328720337961	1.24209101096886	0.652275742264994	0.681409010247009	0.649149341692697	0.248234423731729	NA	NA	0.841784896917234	0.274268859400193	72.5545322776079
a3247	loss_cnaOV34	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.46245367431986	5.73094612495542	0.731507549364446	0.798030070680967	1.31514549245098	0.574667709351368	0.916641585623764	0.556217964904528	0.248289731472022	NA	NA	0.564399310437613	0.173403355292208	72.5545322776079
a3248	loss_cnaOV55	1047	Nutlin-3a	MDM2	8	25	2.07944154167984	1.38629436111989	4.44105562505303	3.5258268799275	0.915228745125525	1.17663847360551	1.60662906580544	0.60204384717536	0.77783343453069	0.569657778889179	0.248537222179654	NA	NA	0.158506034917667	0.100654904153266	72.5706527892524
a3249	loss_cnaOV84	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	25	2.30258509299405	NA	1.57559983009265	2.30864663136601	-0.733046801273358	1.54720942996541	1.21507054469813	0.573361736835096	0.473786409955984	0.603295672396926	0.248653465622451	NA	NA	0.681277483871351	0.316945809135256	72.5706527892524
a3250	PIK3CA_mut	1021	Axitinib	PDGFR, KIT, VEGFR	7	23	0.693147180559945	NA	2.5701003579538	2.51163844745716	0.0584619104966446	1.09675820862557	1.03352384776122	0.0558164613649436	0.0533042835119581	0.056565613481762	0.248679159880742	NA	NA	0.187815654239363	0.903030255685567	72.5706527892524
a3251	loss_cnaOV36	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.41961344144786	2.73569151334062	0.683921928107233	1.52161722512753	0.895626135625324	0.721009055500531	0.449470416615396	0.763624352732539	0.24870774277554	NA	NA	0.965634509157752	0.51943458466446	72.5706527892524
a3252	loss_cnaOV40	295	NVP-BHG712	EPHB4	7	25	2.32630161961136	NA	2.72107154800847	3.3995460571042	-0.678474509095735	0.649349868794485	1.13617906791151	0.641943163057535	1.04485199997856	0.597154557989603	0.248786390182533	NA	NA	0.0582770995391817	0.0580248571061308	72.5706527892524
a3253	loss_cnaOV87, loss_cnaOV88	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.93592222084472	1.7968535518766	1.13906866896812	0.754225695310197	1.3808614394644	0.84422701217201	1.51024908863605	0.824897152179101	0.248803804161454	NA	NA	0.0316044707008357	0.0950362645816291	72.5706527892524
a3254	gain_cnaOV94	257	NPK76-II-72-1	PLK3	7	25	2.32630161961136	NA	3.74639725137614	3.08502404243452	0.661373208941618	0.74421517652195	1.29900903800078	0.547223165178321	0.888685463299082	0.509136726222857	0.249072261452823	NA	NA	0.594745168393324	0.101801286646105	72.6119338326587
a3255	loss_cnaOV102	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	4.26349342594346	3.32161620252189	0.941877223421574	1.45261526439454	1.1780843021268	0.785981927812876	0.648401022974347	0.799499001659895	0.249208273442881	NA	NA	0.318688572796511	0.378560372985782	72.6119338326587
a3256	loss_cnaOV57_(ZNRF3)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	2.28143716314341	1.27977871577314	1.00165844737027	2.52692918416752	1.25294752216143	0.696531930470873	0.396393556909375	0.799441660287844	0.249238300677749	NA	NA	0.468742306878861	0.489318592221792	72.6119338326587
a3257	loss_cnaOV44	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.08284144405357	2.93959856763323	-0.856757123579656	0.225709045985927	1.13674233992562	0.779052371038617	3.79584752501712	0.753695092975701	0.249270077156453	NA	NA	0.382836061115722	0.00290876268691942	72.6119338326587
a3258	PIK3R1_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	2.34682670215427	2.87840900763539	-0.531582305481119	0.670387475721209	0.984548327241492	0.559638004119316	0.79294784692873	0.539925050678321	0.249454630566479	NA	NA	0.965636948893219	0.172782119761606	72.6119338326587
a3259	loss_cnaOV21, loss_cnaOV22	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	0.519644521893853	1.85960284817368	-1.33995832627983	1.30051630439747	1.69046387614261	0.80330384562415	1.03032797185933	0.792657178417452	0.249642790983376	NA	NA	0.221876979943881	0.206367489717927	72.6119338326587
a3260	loss_cnaOV82	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.05905346193482	4.44536701282364	-0.386313550888819	0.42675378893353	0.638395242900799	0.616607972495261	0.905237541895594	0.605132251821696	0.249681202668225	NA	NA	0.263227951305835	0.251954170268902	72.6119338326587
a3261	SMAD4_mut	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.41415102373303	-3.6519447679158	1.23779374418276	2.15071598503964	1.66339640316385	0.716367022722089	0.575526360892299	0.744136359696597	0.249699801701949	NA	NA	0.671910088140583	0.427553446046125	72.6119338326587
a3262	PIK3R1_mut	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	3.47576215377605	2.7410664640391	0.734695689736951	0.428632481606706	1.11047136541259	0.702672469594069	1.71404576476095	0.66160705500405	0.249750740090249	NA	NA	0.29879513104535	0.0208233654414908	72.6119338326587
a3263	gain_cnaOV48_(SOX17)	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.25460819081616	1.65170175169563	-0.397093560879475	0.390245977662478	0.69493836059637	0.584913031885443	1.01754683868368	0.571408319636729	0.249767476062266	NA	NA	0.201616835829849	0.210785519529194	72.6119338326587
a3264	loss_cnaOV35	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.62894539117404	3.59033535866934	1.0386100325047	0.894258530530716	1.59795007220691	0.680831897145239	1.16142032426386	0.649964007367445	0.249787140710344	NA	NA	0.158553887206328	0.0667469295159592	72.6119338326587
a3265	loss_cnaOV36	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	2.93903877454904	3.60699342078468	-0.667954646235639	0.498733417392355	0.910650529866674	0.751231451790079	1.33930196562337	0.733491744998417	0.249913061340614	NA	NA	0.657922874942306	0.124161854105053	72.6170308216436
a3266	loss_cnaOV34	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.27879392096847	4.53000775384443	-0.251213832875957	0.646233088871576	0.680112663900288	0.371870789573346	0.388735639201972	0.369370908983379	0.249982139823344	NA	NA	0.0496053703927455	0.460787187673865	72.6170308216436
a3267	loss_cnaOV16, loss_cnaOV17	1004	Vinblastine	Microtubules	6	25	-2.30258509299405	NA	-2.36253314022801	-3.54382522095288	1.18129208072488	1.91717621346327	1.74245794263407	0.665963142023473	0.616162495877695	0.677945821142245	0.250071358486954	NA	NA	0.132881824738518	0.209714935757038	72.6170308216436
a3268	ARID1A_mut	1149	TW 37	BCL2, BCL2L1	9	24	1.6094379124341	NA	-1.31462603763625	-0.525054812627077	-0.789571225009168	0.68963797838493	0.908701112346899	0.920736764359991	1.14490682032662	0.868900911730971	0.250146877074498	NA	NA	0.0389019323046871	0.0150345315378134	72.6170308216436
a3269	gain_cnaOV50	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	2.04681904026562	2.60466191515019	-0.557842874884574	0.83480787666769	1.0451094210216	0.543366433419104	0.668229050630572	0.533765042840472	0.25019234054572	NA	NA	0.387517162076984	0.286398961525213	72.6170308216436
a3270	loss_cnaOV42	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	4.51158040341568	3.3953728318737	1.11620757154199	0.722673762013034	1.75662749668883	0.664626856810043	1.54455250794321	0.635426448490639	0.250294842234406	NA	NA	0.693506229179163	0.0485083467787675	72.6170308216436
a3271	BRCA1_mut	1030	KU-55933	ATM	4	29	2.30258509299405	NA	4.67966261718821	4.07807503822622	0.601587578961996	0.534640009874623	1.05704505746422	0.590793121055248	1.12521990096303	0.569121982751769	0.250340407563225	NA	NA	0.523004380372795	0.113225226004746	72.6170308216436
a3272	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.39800042688942	3.87894412736813	0.519056299521283	0.699492067103843	0.72021093932429	0.722066572972718	0.742047442611278	0.720700382596615	0.250534296281368	NA	NA	0.955039772946734	0.326387536924002	72.6510620751152
a3273	gain_cnaOV50	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	3.1652464976321	3.76802293610902	-0.602776438476916	1.39816421859108	1.19642673614861	0.495129520182827	0.431119914572216	0.503813915440655	0.250632235085503	NA	NA	0.191124019392269	0.461720057493144	72.6572570468859
a3274	loss_cnaOV81_(RB1)	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.67332012437994	3.91926331980718	0.754056804572753	0.842813785534157	1.04546376905186	0.734232682688781	0.894689690077682	0.721265362697947	0.250782082107726	NA	NA	0.0991990937561457	0.17343202590376	72.6633692089244
a3275	PIK3R1_mut	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.59213297672241	4.21975640881434	0.372376567908075	0.573865951398727	0.931759660919364	0.417288208887829	0.648891203599819	0.399648732958296	0.25080778852163	NA	NA	0.514573511529474	0.266279551521409	72.6633692089244
a3276	gain_cnaOV96	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.34521601338496	4.66903080526451	0.676185208120451	0.606877237093224	1.267647961655	0.556046837097956	1.11420426865768	0.533417185665368	0.250883065471793	NA	NA	0.41688522989784	0.121820306545803	72.6633692089244
a3277	NF1_mut	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	4.42046712410704	3.40887109547498	1.01159602863206	1.48479692968762	1.70922424150918	0.599502536659618	0.681302613445521	0.591845121350995	0.250971504495725	NA	NA	0.69352610777885	0.276760894836573	72.6668022775523
a3278	gain_cnaOV26	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.02718284912318	3.74913482692389	-0.721951977800712	0.660782678056274	1.06105597478527	0.6947331228275	1.09257097950021	0.680408946329923	0.251277091748014	NA	NA	0.828176099534679	0.185741227312696	72.7146424800786
a3279	loss_cnaOV38	254	AC220	FLT3	8	24	0.0237165266173161	NA	2.28259936647861	2.5868928345182	-0.304293468039582	0.941018857458766	0.481279092216066	0.490921612462714	0.323365961933357	0.632259894437659	0.251290003973012	NA	NA	0.855736882536218	0.405196082760547	72.7146424800786
a3280	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1061	SB590885	BRAF	8	25	1.6094379124341	NA	4.37803787643138	3.78338044756016	0.594657428871222	1.61164053128765	1.1470732419682	0.469359923585385	0.368976466728663	0.518412780556959	0.251462124805127	NA	NA	0.56694366448916	0.357287707870975	72.7422640173186
a3281	loss_cnaOV85	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-5.0567911124118	-3.87553005362534	-1.18126105878646	1.01861656204703	2.55090930366172	0.511416825228921	1.15967195390244	0.463074503311745	0.251572807998174	NA	NA	0.9267420272769	0.0838807310150706	72.7440011223764
a3282	loss_cnaOV44	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.551743854291848	-0.420997703466564	0.972741557758412	1.09799060037631	1.40691697895513	0.700287091729519	0.885928857155083	0.691399401889962	0.251621464014571	NA	NA	0.887178137750837	0.259373658132076	72.7440011223764
a3283	gain_cnaOV96	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-1.47548542738681	-2.21296763193021	0.737482204543398	1.41093081659013	1.26508782771887	0.576190309269745	0.522691967509585	0.582949411404252	0.251714133125678	NA	NA	0.601742589363839	0.381667753510896	72.748625905969
a3284	gain_cnaOV48_(SOX17)	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.381663853475555	0.666555738054848	-0.284891884579292	0.297863778934225	0.633043272763318	0.462190701525738	0.956450245809186	0.450035403323538	0.251815849394738	NA	NA	0.0136295710597178	0.239447571014432	72.7558618219517
a3285	MLL2_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	-0.347651868329429	0.663565942506834	-1.01121781083626	1.32169683186098	1.17204394801255	0.854810705728379	0.765090591472817	0.862781478929184	0.251962120197955	NA	NA	0.423018600652869	0.314498278710848	72.7759623268483
a3286	loss_cnaOV38	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	1.77465095450508	2.45661494184193	-0.681963987336844	1.40627915410444	1.16430393491068	0.563362041232534	0.484942115046239	0.585726773644515	0.252048294859781	NA	NA	0.374909614098128	0.421008211515654	72.778697895843
a3287	loss_cnaOV54	1114	Cetuximab	EGFR	11	21	4.18661983833127	NA	6.11327047598209	5.67001576001086	0.443254715971222	1.35979024103108	1.23641068125854	0.346601313501365	0.325972861545998	0.358501202464567	0.252158138081608	NA	NA	0.564545946856349	0.377904209038694	72.7882639946602
a3288	loss_cnaOV41	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-3.4524788988858	-4.31880871965864	0.866329820772835	2.57355897953861	0.981556313948607	0.66093803808814	0.33662714849774	0.882608372501585	0.252243142289168	NA	NA	0.210305012035449	0.496858014519809	72.7906563963556
a3289	loss_cnaOV54	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	10	22	2.32630161961136	NA	5.39456028022207	5.02783860299076	0.366721677231302	0.360437694912405	0.632689594982325	0.649108750615443	1.01743430947316	0.579623373198586	0.25240821943525	NA	NA	0.0106724264575583	0.0470734129934441	72.8161472363396
a3290	SMARCA4_mut	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	0.279850590604757	1.69826522447365	-1.41841463386889	0.864346046332479	1.61687311000491	0.898919909968792	1.64102634574126	0.877257853502547	0.252545823884116	NA	NA	0.07418980419052	0.0771715782018638	72.8336995106379
a3291	loss_cnaOV102	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.44682015088053	0.687034490314228	0.759785660566306	0.589366894150102	1.05604554284529	0.736566667595117	1.28915564838768	0.719462967969377	0.252692575685375	NA	NA	0.768224588008607	0.134755566651453	72.8538783942359
a3292	PIK3CA_mut	1006	Cytarabine	DNA synthesis	7	24	0.693147180559945	NA	0.202670933795985	-0.202886867736189	0.405557801532173	1.14824872936646	1.28535819375991	0.322327350938795	0.353196821524844	0.31552123252573	0.252772350567976	NA	NA	0.763220608509031	0.441106816853283	72.8547407471389
a3293	loss_cnaOV35	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.77201926736763	4.13241467679654	0.639604590571083	1.2652069492117	0.903043853006733	0.66799220977754	0.505533573752179	0.708276335021256	0.253065357380605	NA	NA	0.202515711123206	0.330943427440607	72.9170422051787
a3294	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.66137522600668	3.84040920617215	0.820966019834532	1.1822055977126	1.20761189251603	0.680804157289447	0.694435909813812	0.679826047525975	0.253313129058805	NA	NA	0.693819745271926	0.352453658338953	72.940462779111
a3295	loss_cnaOV20	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-0.997009283003255	-2.4858259850214	1.48881670201815	3.0059688581785	2.5272152776756	0.568669442223535	0.495286801780213	0.5891135255353	0.253371269604068	NA	NA	0.402888904134616	0.412586970460114	72.940462779111
a3296	loss_cnaOV41	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	0.318179799821749	-0.44877137643679	0.766951176258539	1.01464585185382	1.43735032762879	0.551743742271072	0.755880660091667	0.533586810060278	0.253405755788482	NA	NA	0.887196832966364	0.188884342342098	72.940462779111
a3297	loss_cnaOV20	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.47358036873513	1.5373170984458	0.936263270289323	1.29622956376053	1.47744585127354	0.643661871225445	0.722297420507137	0.63370394893476	0.253524151930786	NA	NA	0.318574749735178	0.196422663685234	72.940462779111
a3298	loss_cnaOV33_(ZFHX3)	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.37570722897879	4.87724316214053	0.498464066838256	0.812826553898812	0.807796512758801	0.616693712162169	0.613247764172219	0.617066376203944	0.253623219961725	NA	NA	0.945109913302294	0.316056573637241	72.940462779111
a3299	loss_cnaOV40	301	PHA-793887	CDK-pan	7	25	2.32630161961136	NA	3.67624163457751	2.8232469084245	0.852994726153007	1.56459396040509	1.60257225403806	0.534776523557802	0.545186002080795	0.532266001737945	0.253671335921675	NA	NA	0.658222503844603	0.233956731765307	72.940462779111
a3300	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.40188003221723	3.7713476967724	0.630532335444829	1.07805785026372	0.839922377185009	0.728577186558982	0.584878014932673	0.750703103729718	0.253684759842031	NA	NA	0.938395552409371	0.420133407909818	72.940462779111
a3301	loss_cnaOV20	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.64699787453265	4.2682694996584	0.378728374874247	0.421598763866052	0.59544391964176	0.659115562112213	0.898314718480944	0.63604373540686	0.253777930972418	NA	NA	0.246117625297579	0.128689885882246	72.9451471273292
a3302	loss_cnaOV35	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.45417153623266	5.7321292875393	0.722042248693362	0.790549051547189	1.31632504096154	0.566951081919192	0.913342754988129	0.548528840692669	0.254089535388216	NA	NA	0.564618115323233	0.175214859569062	72.9756671857407
a3303	loss_cnaOV57_(ZNRF3)	309	Y-39983	ROCK	4	28	2.99573227355399	NA	5.69833532474196	4.8594259207002	0.838909404041763	0.553162410236267	1.26647016238968	0.690945982898913	1.51656979671386	0.662399659269383	0.254139409703878	NA	NA	0.364817464358988	0.0486601859320159	72.9756671857407
a3304	loss_cnaOV42	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.31972627222326	2.72588553916101	0.593840733062253	1.2583543907975	0.909838729172797	0.625638590239851	0.47191851310337	0.652687903934534	0.254446345651912	NA	NA	0.965653023292186	0.421211197831539	72.9756671857407
a3305	PIK3CA_mut	253	XMD14-99	EPHB3, CAMK1	6	26	2.32630161961136	NA	4.82595341912655	4.86793552959128	-0.0419821104647351	0.774163423614751	0.591020113287244	0.0671412629878343	0.0542290027972528	0.0710333024560388	0.254472286438794	NA	NA	0.0462281556697087	0.904570852208928	72.9756671857407
a3306	loss_cnaOV1	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.32891634607263	2.28413337590819	1.04478297016444	0.90330661584108	1.30269670133716	0.815794565728887	1.15662052269111	0.802015518341315	0.254734122280011	NA	NA	0.104702866844891	0.168713913173627	72.9756671857407
a3307	TP53_mut	194	AUY922	HSP90	12	7	-1.36257783450257	NA	-2.11191261674525	-3.28906990667669	1.17715728993144	2.36948955037285	0.583445675479537	0.607634874506538	0.496797839748317	2.01759536389387	0.254855185358501	NA	NA	0.330938540973376	0.125137425417293	72.9756671857407
a3308	gain_cnaOV51_(MYC)	224	AS605240	PI3Kgamma	8	24	2.99573227355399	2.32630161961136	2.74180271426333	3.58620052395872	-0.844397809695386	1.91064498953098	1.54778262892131	0.514986935665117	0.441943853684021	0.545553228158317	0.254992384919503	NA	NA	0.624143138401295	0.283312155749542	72.9756671857407
a3309	TP53_mut	207	AS601245	JNK 	11	7	2.07944154167984	NA	2.19845497810611	1.67135216926776	0.527102808838355	0.874200343089302	1.10018688278761	0.546126528339822	0.602954246134985	0.479102975217086	0.255050201902293	NA	NA	0.465351208102245	0.307789626790931	72.9756671857407
a3310	loss_cnaOV41	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.56494594119091	2.88321777011285	0.681728171078059	0.902579347294875	0.993789146710067	0.693873699158281	0.75531106835235	0.685988746541373	0.255166228537927	NA	NA	0.0830099855502164	0.177586892983216	72.9756671857407
a3311	SMAD4_mut	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	5.00814441504303	4.46208766076568	0.546056754277354	0.987773378472933	0.978162060175523	0.557715056215152	0.552815824133204	0.558247734715215	0.255240379041709	NA	NA	0.317986219320312	0.360012970543098	72.9756671857407
a3312	loss_cnaOV59	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	3.9663230855764	2.39022254263044	1.57610054294596	2.58141643544658	2.2567001580644	0.687879961555076	0.61055648414716	0.69840937322298	0.255265810768472	NA	NA	0.378289510851214	0.315823871725004	72.9756671857407
a3313	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.6714396422422	2.55347694121551	1.1179627010267	2.25646220349065	1.63778291030453	0.663649318417263	0.495449336265087	0.682607379764895	0.255269621105927	NA	NA	0.63474084199508	0.483435895897357	72.9756671857407
a3314	SMARCA4_mut	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	3.655547551261	4.34232569889021	-0.686778147629207	1.52259146172236	0.814071549424313	0.781093696936442	0.451058714628757	0.843633643891469	0.255355468921374	NA	NA	0.514756760473546	0.517854612130926	72.9756671857407
a3315	NF1_mut	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	3.55016731235879	4.41240414633606	-0.862236833977272	1.73038717010349	1.23155989127572	0.669281286708207	0.498291277740867	0.700117663854836	0.255424455958746	NA	NA	0.363629822313969	0.398164421819316	72.9756671857407
a3316	loss_cnaOV20	173	FH535	unknown 	3	15	3.46573590279973	NA	3.12718938535887	2.37075378836273	0.756435596996139	1.89832041076961	1.34942891418931	0.529119420216382	0.398476249164633	0.560559796104992	0.255611549367661	NA	NA	0.110382309253964	0.567766031777384	72.9756671857407
a3317	RB1_mut	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	1.82813595453702	2.45202275506335	-0.623886800526323	0.363218340114323	0.959428080141204	0.669673784943334	1.71766326648031	0.65026948182974	0.255637282753983	NA	NA	0.730616380200406	0.0660727047898183	72.9756671857407
a3318	loss_cnaOV82	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.22168519138167	3.49519146674017	0.726493724641499	1.83167798911027	0.795505677901739	0.807985669152391	0.396627425213746	0.913247692408344	0.255740346458916	NA	NA	0.136886009326298	0.56409795781246	72.9756671857407
a3319	KRAS_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	7	25	2.32630161961136	NA	4.8216158930612	5.23226963266356	-0.410653739602362	0.525539900162868	0.574480038758714	0.726780607559307	0.781394028265213	0.71482682059705	0.255837155197578	NA	NA	0.0106954917478428	0.102653441823845	72.9756671857407
a3320	loss_cnaOV82	304	SB52334	ALK5	3	29	2.99573227355399	NA	3.63617634467683	4.44220573137072	-0.806029386693891	1.53252207142201	0.999293336516634	0.772536097213278	0.52594961059581	0.806599381022165	0.256197825207927	NA	NA	0.344094956842444	0.459948614256281	72.9756671857407
a3321	loss_cnaOV42	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	4.13715214784837	3.30602648427042	0.831125663577947	1.23926601581915	1.19362120021391	0.693608181754539	0.670659610582943	0.696306050386004	0.25623057698517	NA	NA	0.319011629824397	0.278669393830477	72.9756671857407
a3322	gain_cnaOV48_(SOX17)	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.01358007758112	4.36318771896566	-0.349607641384535	0.229424013720476	0.60061260519845	0.600024803419359	1.52384938139251	0.58208508838908	0.256343560807729	NA	NA	0.246234839040128	0.0936622799715758	72.9756671857407
a3323	gain_cnaOV50	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	9.66160762029642	8.62356800804452	1.03803961225189	1.50741012154798	1.70486048473666	0.615861733952945	0.688624547104616	0.608870709096315	0.25635923352253	NA	NA	0.920469724786767	0.271834133248204	72.9756671857407
a3324	loss_cnaOV41	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.81898978284698	2.85999686068223	0.958992922164751	0.912831768499103	1.67666796043795	0.600840643713874	1.05056917962172	0.571963528136043	0.256542009199086	NA	NA	0.658310035352724	0.0952534704935436	72.9756671857407
a3325	loss_cnaOV70	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.88638874707124	1.12473812171754	1.7616506253537	1.89727442153446	2.31099915011949	0.770710630910593	0.928516510505069	0.762289603292416	0.256577023984572	NA	NA	0.355790103078153	0.242428773144077	72.9756671857407
a3326	loss_cnaOV16, loss_cnaOV17	1378	Bleomycin (50 uM)	DNA damage	6	26	3.91202300542815	NA	3.04583708425746	1.81022583893507	1.23561124532239	3.1036034978684	1.61112162787348	0.636499942296915	0.398121488834197	0.766926111564446	0.256617220976672	NA	NA	0.126466613533902	0.382811482680057	72.9756671857407
a3327	loss_cnaOV20	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.25598059852596	4.66018433857891	0.595796259947049	0.601670896185817	1.28905243306406	0.48934583771829	0.990236130289815	0.462197071790825	0.256661688405024	NA	NA	0.417150511363617	0.13132374782101	72.9756671857407
a3328	gain_cnaOV72_(ASXL1)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	1.6650626897728	2.41474221217762	-0.749679522404817	0.56701430267834	1.48439294277413	0.537705574820419	1.32215275498985	0.505041152380963	0.256697016500231	NA	NA	0.523022522191612	0.0690998386761695	72.9756671857407
a3329	loss_cnaOV84	222	BX-912	PDPK1 (PDK1)	6	26	2.32630161961136	NA	3.99568547808531	3.27473989547897	0.72094558260634	1.50485300994645	1.12491835147108	0.602471222225975	0.479080400438574	0.640887031190792	0.256755017557728	NA	NA	0.319035318452614	0.309472245623516	72.9756671857407
a3330	gain_cnaOV49	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-1.14804085383668	-0.699627576008867	-0.448413277827812	0.36530872803938	0.947993724023098	0.4865666748974	1.22749127904624	0.473012918191942	0.256891357406147	NA	NA	0.0390162418683461	0.156542977274008	72.9756671857407
a3331	loss_cnaOV70	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	0.102233718078561	0.948599436659348	-0.846365718580787	1.20417082419851	1.23236933455039	0.687817276026161	0.702861837849397	0.686779275378162	0.256945583204795	NA	NA	0.842394822771813	0.347611737689807	72.9756671857407
a3332	TP53_mut	225	Genentech Cpd 10	AURKA, AURKB	22	10	2.32630161961136	NA	2.58162877883176	3.4217047115402	-0.840075932708434	1.96076817178531	1.45776922688161	0.460444815187495	0.428442252784802	0.576274980440823	0.257176189469675	NA	NA	0.338641582213186	0.190074901449306	72.9756671857407
a3333	loss_cnaOV16, loss_cnaOV17	302	PI-103	PI3Ka, PRKDC (DNAPK)	6	26	2.32630161961136	NA	2.39619678872585	1.03459196302566	1.36160482570019	1.87483764162853	2.35426089385718	0.59683796908177	0.726252127366863	0.578357661741285	0.257207061472661	NA	NA	0.355818405519079	0.161800999625393	72.9756671857407
a3334	gain_cnaOV48_(SOX17)	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-2.39749080454096	-0.920996916774994	-1.47649388776597	1.08855673645473	1.98614397378155	0.761364574151541	1.35637752109705	0.743397209495732	0.257253666564816	NA	NA	0.436269569685092	0.120814724053221	72.9756671857407
a3335	gain_cnaOV96	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	2.47514711174696	1.63608381254842	0.839063299198539	1.91770223543269	1.66523635250714	0.496100733164618	0.437535756957191	0.503870395295697	0.257254169587276	NA	NA	0.222196503153569	0.455920581000461	72.9756671857407
a3336	loss_cnaOV84	1219	PFI-1	BRD2, BRD3, BRD4	6	26	2.30258509299405	NA	2.68831670827039	2.28618627651785	0.402130431752545	0.70947059578876	0.890258793047183	0.466096465617732	0.566803521019039	0.451700600873742	0.257262702484414	NA	NA	0.602110992490854	0.264664411330604	72.9756671857407
a3337	gain_cnaOV18_(CCNE1)	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	3.01758852768307	2.1251649223278	0.892423605355268	1.81471219716367	0.999479170603866	0.753208373551872	0.491771426207468	0.892888648010626	0.257294496783905	NA	NA	0.375339719467491	0.40475587697675	72.9756671857407
a3338	loss_cnaOV57_(ZNRF3)	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.620848530396289	0.0162724632744753	-0.637120993670765	1.32426167342224	0.896147322390135	0.672279947749254	0.481114123029987	0.710955640609944	0.257325116473697	NA	NA	0.54249123828401	0.412500742000442	72.9756671857407
a3339	MLL2_mut	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	0.968673934221101	1.34518995643009	-0.376516022208985	1.43119900244331	1.20639493296695	0.307946128499875	0.26307733695049	0.312100135635517	0.257431478762649	NA	NA	0.0924223998626071	0.697963112170963	72.9756671857407
a3340	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.09704933563082	-2.86918057873698	0.772131243106155	1.17243187694395	1.21187867530403	0.639549565414499	0.65857237276658	0.637135761888413	0.257559105115684	NA	NA	0.3650232053112	0.377543968950584	72.9756671857407
a3341	loss_cnaOV40	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	2.85002939935397	1.93679182647125	0.913237572882714	1.72481489698319	1.2065237293545	0.692211081131264	0.529469901077515	0.756916379399603	0.257624078718841	NA	NA	0.888789645399356	0.379015984705078	72.9756671857407
a3342	loss_cnaOV83	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.59869279915914	3.90515516504908	0.69353763411006	0.722052220736171	1.06549608125442	0.675722072232332	0.960508969009141	0.65090585156686	0.257730220315728	NA	NA	0.0994142439650144	0.10891525898775	72.9756671857407
a3343	loss_cnaOV57_(ZNRF3)	293	MP470	PDGFR	4	28	2.99573227355399	NA	4.9323280954332	3.92308767498629	1.0092404204469	1.33965847860684	1.7873281923677	0.577458217009344	0.753356498364008	0.564664298787761	0.257760200666826	NA	NA	0.616587292430121	0.239941438499978	72.9756671857407
a3344	PIK3R1_mut	157	JNK-9L	JNK	3	16	1.63315443905142	NA	-0.364812310588503	0.0309965987071377	-0.395808909295641	1.26911226459587	0.969413546734517	0.392161114752496	0.311878562943113	0.408297274810042	0.257858367695306	NA	NA	0.178197683623847	0.650504322918013	72.9756671857407
a3345	loss_cnaOV44	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	9.82258989635795	8.64339275033264	1.17919714602531	0.783704250710452	1.73359925428512	0.699668379520821	1.50464559169653	0.680201692006137	0.257929556222858	NA	NA	0.920481933985116	0.09395881391375	72.9756671857407
a3346	gain_cnaOV49	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	1.04555411089154	1.79613208824219	-0.750577977350652	2.02628670567517	1.55954925953462	0.470249883273935	0.370420422365923	0.481278787933016	0.257955558308427	NA	NA	0.0381632386251764	0.590799306795077	72.9756671857407
a3347	gain_cnaOV49	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.76253542460256	5.23510251744318	-0.472567092840615	1.03262562453293	0.741743798279538	0.618068771298849	0.457636418866096	0.637102856723206	0.257956991721886	NA	NA	0.325949937133656	0.513706471648601	72.9756671857407
a3348	gain_cnaOV95_(MECOM)	1133	JNJ-26854165	MDM2	8	25	2.30258509299405	NA	3.40111054207497	2.96121529258395	0.439895249491027	0.908103013386108	0.904759837446173	0.485795207943551	0.484411176933285	0.486201123529864	0.257996175177971	NA	NA	0.231761751548232	0.256067376086617	72.9756671857407
a3349	loss_cnaOV83	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	2.50992134361641	1.06396166862742	1.44595967498899	1.78821169256391	2.34983975103323	0.633372530694789	0.808606543063028	0.61534395030691	0.258015524835425	NA	NA	0.355854597774823	0.160388272649777	72.9756671857407
a3350	loss_cnaOV84	281	CH5424802	ALK	6	26	1.63315443905142	NA	4.23578510211231	3.8564873216027	0.379297780509612	0.594022706315267	0.742134844152825	0.527117474142232	0.638524043739679	0.51109011185507	0.258081921740398	NA	NA	0.955072295970114	0.212698176708561	72.9756671857407
a3351	loss_cnaOV1	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.81832021240335	2.23780677791117	0.580513434492178	0.240280648590434	0.920854017194416	0.651697717007018	2.41598080368794	0.630407669025368	0.258231636874332	NA	NA	0.588251693572869	0.0240199886409987	72.9756671857407
a3352	loss_cnaOV82	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.9606278161094	2.33486842455586	0.625759391553545	1.18025142884677	0.91115250643038	0.671765879582641	0.530191598382539	0.686777885301639	0.258329555470193	NA	NA	0.730682277780666	0.457573513849833	72.9756671857407
a3353	loss_cnaOV35	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.449768582890572	-0.121737318820189	0.571505901710761	1.43505318954317	0.922663452415738	0.573391530756536	0.398247191027597	0.619408843185922	0.258483320462829	NA	NA	0.178242010646428	0.566331317138246	72.9756671857407
a3354	SMAD4_mut	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.65295332583303	3.84131155261932	0.81164177321371	1.27044698490659	1.20159173886793	0.672742876201419	0.638863158287068	0.675472164928825	0.258631467931587	NA	NA	0.693971825748713	0.385133218152762	72.9756671857407
a3355	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	211	TL-2-105	CRAF	7	25	2.32630161961136	1.63315443905142	4.1636520961713	4.47788956337964	-0.314237467208331	0.774114856265647	0.579000606383131	0.504449167885799	0.405931322290108	0.542723900016776	0.258738528399756	NA	NA	0.263634288222975	0.347298033737309	72.9756671857407
a3356	gain_cnaOV18_(CCNE1)	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	5.6474304901641	5.12556633282155	0.521864157342556	0.556294659481428	0.776109501700096	0.689379364356424	0.938107437215076	0.672410473263622	0.258777198324737	NA	NA	0.325986660571623	0.159587124113767	72.9756671857407
a3357	loss_cnaOV84	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	6	27	0.693147180559945	NA	3.20286996991867	2.70786540389075	0.495004566027919	1.13405788981116	0.910098219501102	0.521167499809343	0.436489680531515	0.543902356274547	0.258812179034204	NA	NA	0.965666761237702	0.353026115451437	72.9756671857407
a3358	KRAS_mut	1264	SGC0946	Q8TEK3 (DOT1L)	7	26	-0.693147180559945	NA	1.84366900765588	2.1884468480015	-0.344777840345616	0.632819872157332	0.521129471883157	0.63315684642326	0.544827770926728	0.661597278503026	0.258841434808155	NA	NA	0.0394152328130595	0.220214598712559	72.9756671857407
a3359	loss_cnaOV85	229	LY317615	PRKCB (PKCbeta)	7	25	2.99573227355399	2.32630161961136	2.23814363614589	2.89206379967231	-0.653920163526427	0.854441786926326	1.81833219704555	0.391416029440703	0.765318566497979	0.359626345828845	0.258872734182585	NA	NA	0.313691610053505	0.192474293279007	72.9756671857407
a3360	loss_cnaOV38	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	2.82767828752834	2.2846898932621	0.542988394266238	1.1047201759328	0.939672906402394	0.55929755850685	0.491516680961992	0.577848302921821	0.258898824018568	NA	NA	0.39656142967377	0.416338024580289	72.9756671857407
a3361	loss_cnaOV52, loss_cnaOV53	290	KIN001-260	IKK	8	23	2.99573227355399	NA	5.18595899468072	4.73347683041919	0.452482164261528	0.856964299309131	0.895311201561573	0.510582934465431	0.528005851149588	0.505390933870059	0.259015965942449	NA	NA	0.660130017381372	0.226291521740512	72.9756671857407
a3362	loss_cnaOV20	290	KIN001-260	IKK	5	26	2.99573227355399	NA	4.45873167989483	4.9255377176005	-0.466806037705666	1.00586889700422	0.872464494576485	0.523294648879161	0.464082385980872	0.535043019638598	0.25905560078884	NA	NA	0.660131240542454	0.374822559470993	72.9756671857407
a3363	gain_cnaOV19	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.47450296758282	3.7313137627943	0.743189204788515	0.903119578230684	1.02286883855902	0.731971704988996	0.822913402281134	0.726573316902972	0.259109060716141	NA	NA	0.712842341792444	0.286874520680253	72.9756671857407
a3364	NF1_mut	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	3.51797964326025	2.63916720970671	0.878812433553535	2.66728997329579	1.51565284788114	0.527178440155927	0.329477650481191	0.57982435409408	0.259161533994485	NA	NA	0.313704492598906	0.561617235703246	72.9756671857407
a3365	KRAS_mut	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	3.0647860869637	1.96573024741633	1.09905583954738	1.15283939070741	1.54575592373743	0.730335356652005	0.953346882841129	0.711015123843099	0.25924589491731	NA	NA	0.946154625910983	0.235613408843069	72.9756671857407
a3366	loss_cnaOV43_(NF1)	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	2.50671184942225	1.06455601940411	1.44215583001814	1.9293697810512	2.33298008840472	0.631612731541228	0.747475079262615	0.618160368014233	0.259470783537446	NA	NA	0.355919392360057	0.185735124716167	72.9756671857407
a3367	PIK3CA_mut	152	CP466722	ATM	6	26	2.77258872223978	NA	2.26049764286784	2.7360903101237	-0.475592667255856	0.535798387236712	0.84056461760233	0.596058769573985	0.887633629710316	0.565801435483284	0.259506257050069	NA	NA	0.549620212211938	0.109070824018453	72.9756671857407
a3368	loss_cnaOV36	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.12607256648854	-4.15981225397691	1.03373968748837	1.0897747841693	1.53093121608944	0.687023188680118	0.948581030232179	0.675235880374113	0.259608121617753	NA	NA	0.861844404228858	0.234566625166858	72.9756671857407
a3369	SMAD4_mut	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.70099070837839	1.57836177160611	1.12262893677228	1.30921245185154	1.46772969270492	0.770138074752851	0.857484157887905	0.764874446808633	0.259615006899349	NA	NA	0.318849778794821	0.2715096472798	72.9756671857407
a3370	gain_cnaOV50	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	1.91997659259669	2.14225499073253	-0.222278398135842	0.514201797798064	0.563182091150112	0.3978992953645	0.432278531673152	0.394683001517169	0.259817149484111	NA	NA	0.0394314424363937	0.467441142853482	72.9756671857407
a3371	loss_cnaOV54	1010	Gefitinib	EGFR	10	20	-0.693147180559945	NA	1.29399825824531	0.741139878632957	0.552858379612352	1.39697235092982	1.17719521541549	0.441561781596279	0.395754704267677	0.469640355628886	0.259821352452207	NA	NA	0.956739030059777	0.298684177609389	72.9756671857407
a3372	loss_cnaOV40	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.84005082226255	3.11032453943692	0.729726282825637	0.959629388998424	1.00533262052477	0.731001559047214	0.760425109100983	0.725855570512303	0.259841485325894	NA	NA	0.555415208783856	0.236765331587523	72.9756671857407
a3373	gain_cnaOV95_(MECOM)	290	KIN001-260	IKK	9	22	2.99573227355399	NA	5.14488291279005	4.72971331099894	0.415169601791108	0.704344511541293	0.949210874589272	0.46730798411731	0.589441097343979	0.437383950084594	0.260138552757971	NA	NA	0.660164570514533	0.195398542517233	72.9756671857407
a3374	loss_cnaOV44	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.17433806976491	5.73034630129605	0.443991768468853	0.620322294160832	0.54764275075692	0.802933734565218	0.715743691058987	0.810732485466471	0.260203812010337	NA	NA	0.105124269243864	0.340136686195137	72.9756671857407
a3375	MLL2_mut	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.14411623490917	3.73703826977361	-0.592922034864441	1.10296213357782	1.04240430282155	0.566548892351694	0.537572430470575	0.568802367046585	0.260208400252556	NA	NA	0.828319924303041	0.453620518688062	72.9756671857407
a3376	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.64536439253765	3.82673728644328	0.818627106094368	1.1053571656212	1.05237429983919	0.775308465410186	0.740599628387363	0.777885877885329	0.260261849321756	NA	NA	0.309114156579912	0.326970785311927	72.9756671857407
a3377	gain_cnaOV51_(MYC)	301	PHA-793887	CDK-pan	8	24	2.32630161961136	NA	2.50195917217829	3.17913294896787	-0.677173776789578	1.25479691218625	1.7007863016267	0.421173608780409	0.539668029314586	0.398153357739241	0.26049040505872	NA	NA	0.658428442991714	0.246467658759726	72.9756671857407
a3378	loss_cnaOV38	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.6094379124341	NA	1.65381581095122	1.01237246508105	0.641443345870171	1.59698623503951	1.44136180115016	0.434012976603765	0.401658656659805	0.445025909080095	0.260537630488768	NA	NA	0.810247999010407	0.33354271116656	72.9756671857407
a3379	loss_cnaOV81_(RB1)	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	4.25779054664418	3.5991177264852	0.658672820158974	0.802872700323016	1.06042523650933	0.634834193866974	0.820395088653499	0.621140272299791	0.260590528175012	NA	NA	0.82832593892815	0.206285057481387	72.9756671857407
a3380	TP53_mut	1053	MK-2206	AKT1, AKT2	22	10	1.38629436111989	0.693147180559945	1.44307386135095	1.01689055894148	0.426183302409477	1.17705213936746	1.2862417053473	0.351972296479672	0.362076825788281	0.331339981154166	0.260593678274798	NA	NA	0.0925144855187993	0.38563016649493	72.9756671857407
a3381	loss_cnaOV57_(ZNRF3)	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	4.95358177146234	3.74688151846669	1.20670025299565	1.98446772148642	1.63917297495581	0.719048222912686	0.608072502228356	0.736164072634359	0.260726881898711	NA	NA	0.140945103227798	0.316929899717255	72.9756671857407
a3382	loss_cnaOV43_(NF1)	1032	Afatinib	ERBB2, EGFR	5	26	-0.693147180559945	NA	1.15969156580444	0.202750495923429	0.956941069881007	1.16658206135611	1.7149055573004	0.579914040645093	0.820294689572541	0.558013860184475	0.260768378368168	NA	NA	0.834557720096727	0.16268772203923	72.9756671857407
a3383	loss_cnaOV40	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.34254200723985	4.53234904808827	-0.189807040848425	0.572245005745026	0.702137115843303	0.280236689423936	0.331688418322338	0.270327599218932	0.260896622819026	NA	NA	0.0498354785453281	0.478693951947425	72.9756671857407
a3384	loss_cnaOV42	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	1.98375730929782	2.85834182884421	-0.87458451954639	1.22112074135523	1.70967120559229	0.524560594103709	0.716214613286937	0.511551295176316	0.261209190767815	NA	NA	0.313795326739838	0.262631978672163	72.9756671857407
a3385	loss_cnaOV38	1061	SB590885	BRAF	8	25	1.6094379124341	NA	4.31119534747942	3.80477005682479	0.506425290654634	1.26494179028854	1.2771810438734	0.397374699351027	0.400354620696907	0.396518013702083	0.261280461760635	NA	NA	0.567291205253575	0.34496823186466	72.9756671857407
a3386	gain_cnaOV49	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	2.9620997256358	3.82626059405681	-0.864160868421015	1.7695777754525	1.53598979022536	0.55676120930872	0.488342971079663	0.562608471697084	0.261309221051285	NA	NA	0.158981840347205	0.490189549182381	72.9756671857407
a3387	loss_cnaOV85	1025	SB 216763	GSK3A, GSK3B	6	17	2.30258509299405	NA	5.33390819911072	4.82797297491889	0.505935224191822	1.16607699098424	0.647431643051955	0.630886825134714	0.433878061314614	0.781449639697672	0.261426005522587	NA	NA	0.443764369834379	0.351033716903851	72.9756671857407
a3388	loss_cnaOV40	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	3.84685341423115	3.55728051057448	0.28957290365667	1.01746722633283	0.877816299343287	0.319100063302301	0.284601701324919	0.329878704545934	0.261495608623866	NA	NA	0.0543217582312398	0.585731768000616	72.9756671857407
a3389	loss_cnaOV57_(ZNRF3)	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.49285848967724	5.7468184058036	-0.253959916126361	0.523552948636465	0.468217521918907	0.535733141294528	0.48507016680504	0.54239729236435	0.261629295369993	NA	NA	0.374308528579439	0.413711912680356	72.9756671857407
a3390	loss_cnaOV56	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.28241391351877	1.45524796128186	0.827165952236912	2.20023383824912	0.834679019164375	0.791777292584078	0.375944564553715	0.990998854943084	0.261685241459765	NA	NA	0.443804815171975	0.583019628204948	72.9756671857407
a3391	loss_cnaOV39	1039	SL 0101-1	RSK, AURKB, PIM3	10	23	2.30258509299405	NA	5.17170543754335	4.83590548880683	0.335799948736517	0.959427883733917	0.740270617747951	0.414553268050484	0.350000197440213	0.453617826624115	0.26169920970951	NA	NA	0.945150280061913	0.340786181556614	72.9756671857407
a3392	PIK3R1_mut	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	4.49679940840762	3.76730979016355	0.729489618244062	1.25773208396662	1.6256250550104	0.461707454392827	0.58000398299724	0.44874407908249	0.261716140516977	NA	NA	0.71113861996185	0.297055149026006	72.9756671857407
a3393	loss_cnaOV59	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.78959288548871	4.2269910780289	0.562601807459809	0.801381019188001	0.782212592316291	0.717405540182542	0.702040345340179	0.719244119803582	0.261903484752493	NA	NA	0.217770724887735	0.260725979195793	72.9756671857407
a3394	loss_cnaOV44	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	2.62395895695593	1.64917140466748	0.974787552288456	1.42195519799656	1.70714977140723	0.576728120365955	0.685526206213715	0.571002948080486	0.261949864433074	NA	NA	0.22238792466557	0.358548900172637	72.9756671857407
a3395	loss_cnaOV16, loss_cnaOV17	164	JQ12	HDAC	3	16	1.63315443905142	NA	3.05848090608365	1.55678283584958	1.50169807023406	3.31207560465607	1.9659187543277	0.692628626353089	0.453400903084156	0.763865783836837	0.262096075744995	NA	NA	0.651115025486859	0.51795314045079	72.9756671857407
a3396	loss_cnaOV85	304	SB52334	ALK5	7	25	2.99573227355399	NA	4.69223375957403	4.27547435707052	0.416759402503512	1.04202424249817	1.05985985173123	0.394540154796627	0.399951733852529	0.393221237527541	0.262106973817814	NA	NA	0.344358170644674	0.373888215100052	72.9756671857407
a3397	loss_cnaOV59	219	AT-7519	CDK9	4	28	2.32630161961136	NA	2.50371303576381	1.3539926589606	1.14972037680322	1.51639730837246	1.68982677463602	0.687100489984055	0.758192045353341	0.680377654124259	0.262128634004449	NA	NA	0.308647736042776	0.232444963036514	72.9756671857407
a3398	loss_cnaOV38	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.0838262582566986	0.957465099960839	-0.87363884170414	1.35060244254206	0.968742597872141	0.849936992870421	0.646851222969657	0.901827630603941	0.262348297038361	NA	NA	0.339810751803027	0.380726096236145	72.9756671857407
a3399	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1149	TW 37	BCL2, BCL2L1	8	25	1.6094379124341	NA	-0.412757018377808	-0.845235747790144	0.432478729412336	1.47603330380437	0.66121963808964	0.474579881203513	0.293000658113643	0.654062136844317	0.262385615878879	NA	NA	0.0391068205608739	0.445221888614657	72.9756671857407
a3400	loss_cnaOV20	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-0.855494218007896	-1.7634116536067	0.907917435598801	1.72388153026841	1.15120101843818	0.714248648532459	0.526670435095061	0.788669764061331	0.262433049654452	NA	NA	0.611889054340355	0.379267135929379	72.9756671857407
a3401	loss_cnaOV102	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-0.909073325931966	-2.09787571591759	1.18880238998563	2.17495586464696	2.00803726212293	0.588742602393692	0.546586902892667	0.592022076686369	0.262643488706035	NA	NA	0.271194985791867	0.446700058370458	72.9756671857407
a3402	loss_cnaOV58	1262	UNC1215	LMBL3	5	28	0	NA	3.05899546978025	2.73066578217511	0.328329687605135	0.59523117937754	0.465013617251881	0.678662431438645	0.551600284024912	0.706064672999221	0.262678662649179	NA	NA	0.104621781954202	0.295177079059863	72.9756671857407
a3403	loss_cnaOV40	1008	Methotrexate	Dihydrofolate reductase (DHFR)	7	24	-1.6094379124341	NA	1.08689556230861	0.413692577043449	0.673202985265164	1.24451011213078	1.17223735897585	0.566883303687134	0.540938139998354	0.574288969815228	0.262683087782677	NA	NA	0.423500359420627	0.232887364059809	72.9756671857407
a3404	PIK3CA_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	7	24	0.693147180559945	NA	-1.15573062473174	0.133292302328565	-1.2890229270603	1.27029618672139	1.58279985823401	0.846141725924837	1.01474202672941	0.814394138560583	0.262718709297032	NA	NA	0.0953844800441155	0.0457876037200861	72.9756671857407
a3405	loss_cnaOV54	275	I-BET	BRD2, BRD3, BRD4	10	21	2.99573227355399	NA	4.23671400378317	3.76897349585754	0.467740507925628	1.08297871790013	1.26409385481167	0.386310678021567	0.431901846448622	0.370020395356888	0.262775362708962	NA	NA	0.694087623943024	0.299810029726381	72.9756671857407
a3406	loss_cnaOV102	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.36939114110248	-2.19899432040719	0.829603179304715	1.10147800923798	1.29179092664787	0.647941907853028	0.753172711889771	0.642211647559324	0.262794826867849	NA	NA	0.602108935258091	0.321011868534791	72.9756671857407
a3407	gain_cnaOV48_(SOX17)	255	CP724714	ERBB2	3	29	2.32630161961136	NA	3.80425710177963	4.47825704645568	-0.673999944676051	1.23719668700477	0.911265278129286	0.71967815463922	0.544779946273369	0.739630885596441	0.262883385537096	NA	NA	0.783176174302413	0.44672428563815	72.9756671857407
a3408	PIK3R1_mut	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	4.4270543171161	4.94025084068712	-0.513196523571024	0.535889157215981	0.603771887289082	0.862271169340543	0.957654239987149	0.849984132045731	0.26294657461135	NA	NA	0.0463905318446267	0.101888707306475	72.9756671857407
a3409	loss_cnaOV83	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.59743641846971	2.26703504300066	1.33040137546904	1.74051181796892	1.50232139753843	0.87078843330293	0.764373652470541	0.885563753301339	0.263068994353832	NA	NA	0.216769085062635	0.315035262984882	72.9756671857407
a3410	loss_cnaOV34	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	1.69408952672929	0.876416307793399	0.817673218935889	1.34505748385835	1.5583836839149	0.533848490774009	0.607909497362416	0.524693133902538	0.263091382216788	NA	NA	0.787797247464548	0.268221953375193	72.9756671857407
a3411	loss_cnaOV55	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	8	25	-1.38629436111989	0.693147180559945	-1.58331229841329	-2.52703612689718	0.943723828483884	1.83501141675683	1.48981727717964	0.599420404411654	0.514287714978801	0.633449378618052	0.263100549069512	NA	NA	0.118927578169672	0.21527258168832	72.9756671857407
a3412	loss_cnaOV36	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.87061316210836	1.15060399354013	0.720009168568222	0.110644387941721	1.27177030760342	0.585191314334862	6.50741697760095	0.566147176312866	0.263138083888091	NA	NA	0.259893945583098	0.0054285091802853	72.9756671857407
a3413	loss_cnaOV44	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.55549298847603	3.60890573907539	0.946587249400633	1.27123901847867	1.19692434091956	0.78760355626216	0.744617837905447	0.790849694537416	0.263231154221146	NA	NA	0.191621813614081	0.324876397310723	72.9756671857407
a3414	loss_cnaOV40	1042	BIRB 0796	p38, JNK2	8	25	2.30258509299405	NA	4.09282605974345	4.49499376620152	-0.402167706458066	1.13999498125674	0.743164162518584	0.473618194240303	0.352780242957484	0.541155947422329	0.263273049631283	NA	NA	0.86755771312941	0.373656837202228	72.9756671857407
a3415	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-1.86685819294666	-2.89242829436458	1.02557010141792	1.61792183832416	1.75954609883148	0.588958430228949	0.633881116581134	0.58286060370854	0.263485515724121	NA	NA	0.691752517087451	0.247327682466519	72.9756671857407
a3416	loss_cnaOV20	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.11390617467953	2.2479006943595	0.866005480320034	1.68652015593936	1.20590227765497	0.677565319851324	0.513486587913136	0.718139020355852	0.26354213167817	NA	NA	0.104968108107268	0.324197830447333	72.9756671857407
a3417	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-0.203949213397777	-0.836185849099542	0.632236635701764	1.47169049610098	0.782163899276364	0.701486271546979	0.429598911847823	0.808317331299351	0.263640248400192	NA	NA	0.0391271948793337	0.397036395575026	72.9756671857407
a3418	gain_cnaOV72_(ASXL1)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	1.6094379124341	NA	1.98390810788022	1.21604961018839	0.767858497691835	1.53078819602333	1.29714892319256	0.576550820233592	0.501609889393303	0.591958628622204	0.263691525226814	NA	NA	0.574743617462809	0.339760029676478	72.9756671857407
a3419	SMARCA4_mut	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.03470922788831	3.59709647733579	-0.562387249447477	0.300693209613904	0.923690621186466	0.627845869020971	1.87030245933918	0.60884806725124	0.26369263686046	NA	NA	0.658339875434085	0.0530849089924593	72.9756671857407
a3420	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	2.69005520696014	1.41115581190832	1.27889939505182	0.670776287388235	1.95431301511821	0.674534680467093	1.9065960128546	0.654398443421542	0.263749057121129	NA	NA	0.779282039258	0.0484171180696541	72.9756671857407
a3421	PIK3CA_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	6	26	1.65632149833295	0.0237165266173161	4.1552389128355	4.52040220588527	-0.365163293049768	0.350197510161162	0.572011571066998	0.674491036475007	1.04273526354233	0.638384451504388	0.263845681528927	NA	NA	0.357493051960415	0.0672722683323701	72.9756671857407
a3422	loss_cnaOV35	309	Y-39983	ROCK	5	27	2.99573227355399	NA	4.47414055417193	5.05505793732273	-0.580917383150797	1.73411363963111	1.13061311838569	0.472931625522824	0.334993837701648	0.513807396804526	0.263899108276366	NA	NA	0.3652503879294	0.505385934045852	72.9756671857407
a3423	gain_cnaOV49	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	3.29639814582561	3.895873937049	-0.59947579122339	0.459801745626025	0.873999614342774	0.702484107199236	1.30377015077922	0.685899377283114	0.26395362993183	NA	NA	0.922594858915063	0.131326954143817	72.9756671857407
a3424	PIK3R1_mut	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	3.2935438834939	2.45643718957365	0.837106693920252	2.43763516111157	2.31602859050342	0.358871396338633	0.343409344956498	0.361440570013989	0.263990394778178	NA	NA	0.378673497365904	0.506609360566954	72.9756671857407
a3425	gain_cnaOV95_(MECOM)	170	Shikonin	unknown	5	13	2.77258872223978	NA	0.360393075134045	-0.154232614838622	0.514625689972667	0.522856144879241	0.829942004044824	0.672872907030804	0.98425866275613	0.620074279244303	0.264044333431715	NA	NA	0.572685038387285	0.14316926555125	72.9756671857407
a3426	gain_cnaOV50	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	1.67725075710391	2.43586142729641	-0.758610670192498	1.23089949966173	1.57466654828142	0.491090921426508	0.616305937569214	0.481759564283907	0.264108019788775	NA	NA	0.235274394325538	0.321669319551996	72.9756671857407
a3427	PIK3CA_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	3.44486252285368	3.91490032317694	-0.470037800323251	1.13867385908391	0.845918117766294	0.535341242917071	0.412794055623099	0.555654017157617	0.264160908813537	NA	NA	0.938483826721606	0.553742711624813	72.9756671857407
a3428	loss_cnaOV39	1011	ABT-263	BCL2, BCL2L1, BCL2L2	10	23	0.693147180559945	NA	2.0656448507212	1.59524219581218	0.470402654909025	1.28995584988285	1.84185833739146	0.276677177961677	0.364665701505789	0.255395675855959	0.264264802743836	NA	NA	0.222480751355866	0.409333910845903	72.9756671857407
a3429	gain_cnaOV50	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	0.231941284933068	0.960297131343733	-0.728355846410664	0.93722564184861	1.26022064115374	0.591323455901952	0.777140331941874	0.577958987994236	0.264360407323361	NA	NA	0.842502091322178	0.227825265813948	72.9756671857407
a3430	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	6.05289306513548	5.44353334203752	0.609359723097966	0.890917648411329	0.972216102639378	0.633579274479922	0.683968629630996	0.626773946084284	0.264368468844072	NA	NA	0.296830084432598	0.216216391147007	72.9756671857407
a3431	loss_cnaOV56	1262	UNC1215	LMBL3	3	30	0	NA	3.13402531004431	2.74505144398905	0.388973866055268	0.782130569791944	0.457762846298167	0.80154976320726	0.497325997830182	0.849727908677644	0.264482630000478	NA	NA	0.104674918344567	0.481127488802055	72.9756671857407
a3432	NF1_mut	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.07735512821825	4.54660701663783	-0.469251888419581	0.741900711346868	0.681893672930274	0.682121954990774	0.63249958012264	0.68815990974529	0.264599161808803	NA	NA	0.0771905510969759	0.301665618139942	72.9756671857407
a3433	gain_cnaOV49	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.14472846806577	4.48371398020112	-0.338985512135354	0.141837856506366	0.569790839502731	0.61445245310879	2.38995089523324	0.594929733217884	0.264617466263255	NA	NA	0.357526519109814	0.026407452139983	72.9756671857407
a3434	loss_cnaOV33_(ZFHX3)	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	3.91275548986276	2.88085150690015	1.03190398296261	1.09908030653615	1.64377245678215	0.645875818217301	0.938879513012798	0.627765709727654	0.264643727827009	NA	NA	0.658550584700121	0.161179538869636	72.9756671857407
a3435	gain_cnaOV18_(CCNE1)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-1.10220272272999	-2.11223036428978	1.01002764155979	2.67614807115951	1.93813307789858	0.499676090134091	0.377418444235103	0.521134308617711	0.264700442285646	NA	NA	0.27128063221974	0.512441818370132	72.9756671857407
a3436	SMARCA4_mut	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.36476824883735	4.83958474501462	-0.474816496177271	0.815904200273177	0.641177022270614	0.72570973314199	0.581951283028443	0.740538852274825	0.264723360942979	NA	NA	0.758504573956171	0.421070948203049	72.9756671857407
a3437	TP53_mut	179	5-Fluorouracil	DNA antimetabolite	21	10	3.46573590279973	NA	4.11731712683052	3.4516468421009	0.665670284729626	1.84744704934362	1.31163202071854	0.391723579177254	0.360319006147501	0.507512987038056	0.264738959590426	NA	NA	0.141091636495496	0.260999717404594	72.9756671857407
a3438	gain_cnaOV51_(MYC)	1072	BMS-708163	g-secretase	8	25	1.6094379124341	NA	3.540529525686	3.93764705373835	-0.397117528052349	0.848908666787955	0.855254102210288	0.465103914106347	0.467797707325731	0.464326949179258	0.26474463555048	NA	NA	0.922600252564077	0.272874091349023	72.9756671857407
a3439	loss_cnaOV16, loss_cnaOV17	1021	Axitinib	PDGFR, KIT, VEGFR	6	24	0.693147180559945	NA	3.04601605593429	2.3950954358994	0.650920620034888	0.924270650826959	1.03062365298252	0.642915206131127	0.70425326115516	0.631579353094792	0.264769961068316	NA	NA	0.188517887121501	0.168469180202231	72.9756671857407
a3440	loss_cnaOV36	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	1.08757238229599	0.2004792435284	0.887093138767587	1.19688789184678	1.11182329204768	0.793814570998077	0.74116644074226	0.797872418317306	0.264876442471981	NA	NA	0.14103302816366	0.326654990246207	72.9756671857407
a3441	loss_cnaOV85	238	CAL-101	PI3Kdelta	7	25	2.99573227355399	2.32630161961136	4.79656583121045	4.27260582534948	0.52396000586097	0.921530767198837	0.979336450875987	0.541252204274843	0.568575705240578	0.535015321233375	0.265073175549968	NA	NA	0.504980654492664	0.218698823810114	72.9756671857407
a3442	gain_cnaOV51_(MYC)	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	1.92488272742348	2.40164047194827	-0.476757744524788	1.43093922956867	0.672650053872717	0.538964061035634	0.333178191409637	0.708775301183583	0.265133301047183	NA	NA	0.588497557688932	0.421995483169846	72.9756671857407
a3443	PIK3CA_mut	286	KIN001-236	TIE2	6	26	2.32630161961136	NA	4.98701247820514	4.75077644164251	0.23623603656263	0.49547453890398	0.691544075702925	0.356364652377127	0.47678743913905	0.341606623298025	0.265150958422219	NA	NA	0.75851368663665	0.354693347106429	72.9756671857407
a3444	loss_cnaOV16, loss_cnaOV17	286	KIN001-236	TIE2	6	26	2.32630161961136	NA	5.08237253227755	4.72877027531811	0.353602256959438	0.735378638642933	0.636927453616463	0.540374298581666	0.480843797165465	0.555168810751822	0.26534488212378	NA	NA	0.758517813286335	0.313665529511941	72.9756671857407
a3445	gain_cnaOV4_(KRAS)	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.94740973198047	4.48792488205926	0.459484849921212	0.602166027249605	0.997358674676736	0.493101398799011	0.763053425680473	0.460701713022289	0.265433535930288	NA	NA	0.942259869874353	0.148049724064753	72.9756671857407
a3446	loss_cnaOV43_(NF1)	272	AR-42	HDAC	5	25	1.63315443905142	NA	1.03874600171778	0.146368129565591	0.892377872152187	1.44107594906663	1.88423117549563	0.488301412853294	0.619244164563408	0.473603177655447	0.265465623291366	NA	NA	0.478868931532619	0.270536852835558	72.9756671857407
a3447	gain_cnaOV49	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.0271088484222	4.49547549609801	-0.468366647675807	0.360493879164426	1.0121694965018	0.47682134054188	1.29923606126521	0.462735390954331	0.265587724296567	NA	NA	0.0289591151208548	0.143621283425076	72.9756671857407
a3448	PTEN_mut	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	1.84774032370557	2.63212104846882	-0.784380724763252	0.608823931634854	1.04356846378277	0.776837129779734	1.28835396246166	0.751633220038095	0.265695066070041	NA	NA	0.388179355758283	0.0740806177608152	72.9756671857407
a3449	loss_cnaOV52, loss_cnaOV53	186	Bexarotene	Retinioic acid X family agonist	5	13	2.07944154167984	NA	4.22136933410397	3.60982054238599	0.611548791717981	0.563420792821608	1.04815061533038	0.643441354241402	1.08542105564715	0.583455071030244	0.265719787276579	NA	NA	0.802135545894846	0.134773179176787	72.9756671857407
a3450	loss_cnaOV81_(RB1)	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.81378815707242	3.87919178378313	0.934596373289292	0.504513902954494	1.17564599747179	0.818318681322123	1.85246901585107	0.794964109348503	0.265763524541152	NA	NA	0.0782858317392768	0.0523426943839816	72.9756671857407
a3451	loss_cnaOV87, loss_cnaOV88	1262	UNC1215	LMBL3	3	30	0	NA	3.13321753566923	2.74513222142656	0.388085314242674	0.941695709041663	0.436625610362624	0.79961562331671	0.412113287250314	0.888828563950621	0.265820695769598	NA	NA	0.104714050333609	0.550553249587458	72.9756671857407
a3452	loss_cnaOV87, loss_cnaOV88	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	3.25832224501033	2.4438303726726	0.814491872337728	0.553415892711979	1.04387733793893	0.801096581040819	1.47175367217295	0.78025630285824	0.265822028429525	NA	NA	0.188561982757592	0.099814552590188	72.9756671857407
a3453	gain_cnaOV18_(CCNE1)	1030	KU-55933	ATM	4	29	2.30258509299405	NA	4.73853950002926	4.06995408886883	0.668585411160429	0.927086635849499	1.02234944267607	0.65966550413331	0.721168211585531	0.653969556055473	0.265893421497193	NA	NA	0.523588759882982	0.251601994572162	72.9756671857407
a3454	loss_cnaOV54	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	11	22	-2.30258509299405	NA	0.0286016616609439	-0.513150809972352	0.541752471633296	1.17765654721471	1.48602663106487	0.388624481698632	0.460025864853894	0.364564443401046	0.265912372841375	NA	NA	0.887323389989494	0.265824306672117	72.9756671857407
a3455	gain_cnaOV50	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	2.6249251528249	3.79220521786362	-1.16728006503872	1.88337503234765	2.01771623566227	0.582275389530008	0.619781002185045	0.578515474281044	0.265985920399107	NA	NA	0.74364007494806	0.313843064984653	72.9756671857407
a3456	loss_cnaOV44	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	4.23732175423098	3.32432361683697	0.912998137394008	1.49782064570139	1.17624702592687	0.760598256816733	0.609551043387091	0.776195915713006	0.265995334093186	NA	NA	0.31944313645364	0.402794173040365	72.9756671857407
a3457	loss_cnaOV38	1192	GSK269962A	ROCK1, ROCK2	8	24	1.6094379124341	NA	3.05258586577363	2.23534076485882	0.81724510091481	1.73897382352353	1.31339535845489	0.573860444069555	0.469958253459444	0.622238456725047	0.266040293210485	NA	NA	0.233097124270372	0.25155533764928	72.9756671857407
a3458	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1248	FK866	NAMPT	7	25	0	NA	-0.695290058541143	-1.99201670263222	1.29672664409107	3.37748563290106	2.53553805094955	0.475894411901101	0.383932541846895	0.511420699683625	0.266183842048159	NA	NA	0.0415944154677085	0.372808898605665	72.9756671857407
a3459	loss_cnaOV36	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.55094926056316	3.60936011186668	0.941589148696484	1.2682186261853	1.19751591818227	0.783219848860002	0.742450181108525	0.786285288070106	0.266224209802474	NA	NA	0.191735806907082	0.32600101875208	72.9756671857407
a3460	ARID1A_mut	265	Tubastatin A	HDAC6	8	23	2.99573227355399	NA	4.63670280868253	4.79787275331397	-0.161169944631435	1.22398161542447	1.24017845955295	0.130365986624429	0.131676769160901	0.12995705851038	0.26638280280956	NA	NA	0.417580444872977	0.754518988238171	72.9756671857407
a3461	gain_cnaOV18_(CCNE1)	164	JQ12	HDAC	4	15	1.63315443905142	NA	2.82624228957053	1.51859992890415	1.30764236066638	2.57340796496342	2.07609291763039	0.602005417200325	0.508136439487926	0.629857339024547	0.266428594885105	NA	NA	0.651350756194409	0.400025401074442	72.9756671857407
a3462	BRCA1_mut	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.41171292920185	2.92786122594162	0.483851703260239	1.40136987023443	0.948334643117671	0.483283063897243	0.345270519609002	0.51021198768988	0.266603110162319	NA	NA	0.0833111544419966	0.545862956887705	72.9756671857407
a3463	loss_cnaOV1	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.84513783607963	3.63795678301243	1.20718105306721	0.589322728531924	1.57621461259324	0.78805311250057	2.04842100028018	0.765873532336509	0.266619455398914	NA	NA	0.159171437773683	0.0371145549689672	72.9756671857407
a3464	loss_cnaOV34	308	XL-880	MET	5	27	1.63315443905142	NA	-0.247654986908032	0.345830509526292	-0.593485496434324	0.465167789240512	1.00787404404546	0.622408803430035	1.27585252066425	0.588848874460699	0.26666171813242	NA	NA	0.361058375829816	0.0579836590396656	72.9756671857407
a3465	gain_cnaOV18_(CCNE1)	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	4.12300297420135	3.30804779479142	0.814955179409933	1.40410385720105	1.17463521465039	0.67937897179486	0.580409472725523	0.69379426842102	0.267037170038345	NA	NA	0.319488013122698	0.336348898016393	72.9756671857407
a3466	gain_cnaOV18_(CCNE1)	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.66299215548917	1.83596592776697	0.827026227722204	1.78439948459229	1.26156757819516	0.625029211806962	0.463475939588253	0.655554440377559	0.267079283037664	NA	NA	0.83661072097822	0.428696504399085	72.9756671857407
a3467	loss_cnaOV54	1016	Temsirolimus	MTOR	10	21	-1.6094379124341	NA	-1.36953646313706	-2.34355865653588	0.974022193398828	1.42622719773239	1.53462409279527	0.648560701116808	0.682936207462219	0.634697577062456	0.267336981013922	NA	NA	0.0351085763431446	0.0990840582978994	72.9756671857407
a3468	loss_cnaOV16, loss_cnaOV17	1199	Tamoxifen	ER	6	26	1.6094379124341	NA	4.32653365014703	3.89984030622789	0.426693343919141	0.825792455000548	0.731817939227291	0.570216668608155	0.516707728843149	0.583059420994348	0.267366079978938	NA	NA	0.519287136043716	0.282719577623128	72.9756671857407
a3469	gain_cnaOV26	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.0465734657128249	-1.17383115162883	1.22040461734166	3.37981181866635	1.81122346528697	0.624138053927768	0.361086558311173	0.673801240283898	0.267423919234929	NA	NA	0.436695946525994	0.597332946782675	72.9756671857407
a3470	loss_cnaOV41	305	TPCA-1	IKK	5	27	2.99573227355399	NA	2.75855573946965	3.43012820994568	-0.671572470476034	1.04293976819341	1.23919197945623	0.552799085370076	0.643922583985208	0.541943848580043	0.267462771728634	NA	NA	0.993513547400884	0.245008726693856	72.9756671857407
a3471	gain_cnaOV4_(KRAS)	1264	SGC0946	Q8TEK3 (DOT1L)	7	26	-0.693147180559945	NA	2.31854899065151	2.06059454488729	0.257954445764215	0.390272721362118	0.585385417241478	0.466446516118739	0.660959456412712	0.44065745091461	0.267470197603524	NA	NA	0.0395561708325843	0.188892248003168	72.9756671857407
a3472	loss_cnaOV70	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-3.38798623980837	-1.84998442452995	-1.53800181527842	1.16617491903701	2.04330892042416	0.769627549989073	1.31884315995104	0.752701561621506	0.267525603896902	NA	NA	0.271396931560523	0.128871241665584	72.9756671857407
a3473	loss_cnaOV52, loss_cnaOV53	1047	Nutlin-3a	MDM2	9	24	2.07944154167984	1.38629436111989	4.37901275201054	3.51095842627154	0.868054325739005	1.1162715611494	1.6394262566614	0.570437159727284	0.777637230894954	0.529486655597884	0.267697125728969	NA	NA	0.159209352938828	0.0972485846651982	72.9756671857407
a3474	gain_cnaOV72_(ASXL1)	1061	SB590885	BRAF	5	28	1.6094379124341	NA	4.54014348868803	3.81814631275053	0.721997175937498	0.760079435901624	1.32470971644173	0.570260314269391	0.94989700001691	0.545022933686057	0.267706592364263	NA	NA	0.567509929724987	0.120945958201177	72.9756671857407
a3475	gain_cnaOV49	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.17144052232234	4.55182871059732	-0.380388188274978	0.35231696129246	0.606701404858447	0.641305748264203	1.0796760589656	0.626977595945617	0.267767972762049	NA	NA	0.609672468013021	0.189787493608303	72.9756671857407
a3476	gain_cnaOV96	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.151075783357865	-0.821677472701538	0.670601689343673	1.02802012729148	0.888941860849156	0.742360186433769	0.652323501788342	0.754381944284956	0.26778058729955	NA	NA	0.0391936351746857	0.288073178921585	72.9756671857407
a3477	gain_cnaOV18_(CCNE1)	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	4.7836263192523	4.38083397882378	0.402792340428525	0.789658988100201	0.724290583866004	0.550947316270931	0.510083905202652	0.556119807989998	0.267804163892319	NA	NA	0.518070141206931	0.392936493207863	72.9756671857407
a3478	PIK3R1_mut	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	3.21778426179351	2.66221033836524	0.555573923428272	2.23006122307557	1.57963032744198	0.330510041814536	0.24912944885973	0.3517113553574	0.267809008519252	NA	NA	0.314082192893845	0.617995294604591	72.9756671857407
a3479	loss_cnaOV16, loss_cnaOV17	225	Genentech Cpd 10	AURKA, AURKB	6	26	2.32630161961136	NA	3.71175337453013	2.64393692317385	1.06781645135628	1.7429244700513	1.83267003043637	0.587351284185539	0.612657903256615	0.582656143016659	0.267873389996343	NA	NA	0.339110890003071	0.218232663890259	72.9756671857407
a3480	gain_cnaOV72_(ASXL1)	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	3.90739588234115	4.47607877927794	-0.568682896936793	0.861495000139691	0.986096226112939	0.586024805752043	0.660111662684729	0.576701220304296	0.267991945269811	NA	NA	0.505092354658226	0.232755189646197	72.9756671857407
a3481	PTEN_mut	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.9942504765609	4.35515428354727	0.639096193013622	0.282832805903938	0.968748301227144	0.680798825645881	2.2596254029693	0.659713356094725	0.268037482448143	NA	NA	0.783275190410178	0.0276674783087552	72.9756671857407
a3482	gain_cnaOV51_(MYC)	229	LY317615	PRKCB (PKCbeta)	8	24	2.99573227355399	2.32630161961136	3.42180762443838	2.52475581038842	0.897051814049965	1.90308371724215	1.55885392318663	0.545112363644516	0.471367499980465	0.575455981286688	0.268047565573579	NA	NA	0.314092396984438	0.255007027027797	72.9756671857407
a3483	PTEN_mut	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	0.42248587694879	-1.21271864244635	1.63520451939514	2.98140329248398	1.82935586126142	0.848267447829959	0.54846807324505	0.893869013690751	0.268048335197857	NA	NA	0.436721461245766	0.443453878428282	72.9756671857407
a3484	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	2.75242223463741	1.57106192092246	1.18136031371496	1.26433866739211	1.59023056862737	0.757438310158431	0.934370152699426	0.742886180797456	0.268072770402109	NA	NA	0.0383359513676204	0.159268633128895	72.9756671857407
a3485	ARID1A_mut	223	ZSTK474	PI3K	8	24	1.63315443905142	2.32630161961136	0.421264547924472	0.870597678681601	-0.449333130757129	0.591027849089152	1.13891774172639	0.4331788178514	0.760257120624025	0.394526412483505	0.268107841788142	NA	NA	0.768547500225678	0.163548603189138	72.9756671857407
a3486	SMAD4_mut	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.30195874056294	3.77784750298949	0.524111237573456	1.24208890368803	0.80092318327211	0.613972233771979	0.421959519980619	0.654383901627419	0.268135266804904	NA	NA	0.922623143082399	0.466119934005028	72.9756671857407
a3487	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	3.18337628812653	2.22403128769761	0.959345000428921	0.362035334879146	1.47415941387121	0.67216902771572	2.64986565675742	0.650774259148564	0.268242231814974	NA	NA	0.818258575885565	0.016280924356351	72.9756671857407
a3488	loss_cnaOV84	226	GSK1070916	AURKB	6	26	0.940007258491471	2.32630161961136	2.8829721091229	2.18266167511049	0.700310434012407	0.624207610713708	1.53978392923027	0.49022911587539	1.1219190890859	0.454810847624893	0.268359885649068	NA	NA	0.818260460964302	0.0910367316657564	72.9756671857407
a3489	loss_cnaOV39	1025	SB 216763	GSK3A, GSK3B	9	14	2.30258509299405	NA	5.24152799624233	4.77894555729319	0.46258243894914	1.022382769737	0.626722274307912	0.577620604172118	0.45245523755074	0.738097970843575	0.268479197826533	NA	NA	0.44418642722054	0.246748384199322	72.9756671857407
a3490	SMARCA4_mut	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-5.66685571518706	-4.53947347872233	-1.12738223646473	0.281606799601539	1.43958207467474	0.810470546194691	4.00339138848892	0.78313161597226	0.26873726300405	NA	NA	0.129615387444676	0.00220984982740706	72.9756671857407
a3491	loss_cnaOV58	1028	VX-702	p38	5	26	0.693147180559945	NA	3.79340470380206	3.23727009044839	0.55613461335367	0.72395669084191	0.935543357143569	0.611613535976705	0.768187683584946	0.594450924275362	0.268876340402792	NA	NA	0.511555659299874	0.179515307409963	72.9756671857407
a3492	loss_cnaOV16, loss_cnaOV17	1003	Camptothecin	TOP1	6	25	-2.30258509299405	NA	-2.84618019589816	-3.89396495635627	1.04778476045811	1.96148814100227	1.62805473708408	0.619902030105958	0.534178483446104	0.643580794055329	0.268913048624028	NA	NA	0.237997855778973	0.266181614873258	72.9756671857407
a3493	PTEN_mut	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	2.64188220301677	1.30368754517843	1.33819465783834	2.24503992977527	1.71698715386659	0.760985273863507	0.596067196886024	0.7793853639643	0.268981856755215	NA	NA	0.609098484546179	0.411582327221058	72.9756671857407
a3494	loss_cnaOV42	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	3.09736107524118	4.00165212167873	-0.90429104643755	0.60679630272635	1.64868344603567	0.574798354727289	1.49027118717525	0.548492828391015	0.269123605093036	NA	NA	0.711330891600369	0.062669606859234	72.9756671857407
a3495	gain_cnaOV19	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.23371547259667	2.46737750942093	0.766337963175734	1.04013659383933	1.017133688611	0.75231967274002	0.736766659027967	0.753428946220673	0.269192287312158	NA	NA	0.388322104738845	0.329011570441998	72.9756671857407
a3496	loss_cnaOV44	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	4.00499341068041	3.20079753810021	0.804195872580199	0.895494328932619	1.02998426884435	0.787216198748149	0.898046862606888	0.78078461672285	0.269439879453135	NA	NA	0.0873373800839695	0.254575681421565	72.9756671857407
a3497	gain_cnaOV49	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.394373992206222	0.665240896117193	-0.27086690391097	0.302850695075829	0.633471892313604	0.439029528154357	0.894390893978795	0.427591037893874	0.269528027952888	NA	NA	0.013769638631138	0.26558069425312	72.9756671857407
a3498	loss_cnaOV36	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.00228474503243333	-1.45344536297793	1.45116061794549	2.11620764063355	1.81437515108953	0.790374553365982	0.68573640416072	0.799812881627085	0.269597818633352	NA	NA	0.0700804041761971	0.356740871187175	72.9756671857407
a3499	gain_cnaOV48_(SOX17)	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.08173193020618	4.43401696833391	-0.352285038127728	0.813224790626693	0.767699214041883	0.456963952877908	0.433195153650256	0.458884197982921	0.269688744208239	NA	NA	0.0401360678676903	0.536849858163118	72.9756671857407
a3500	loss_cnaOV83	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.81385049766205	3.20773576532019	0.606114732341855	0.190161893530618	1.17141218482709	0.554677385307452	3.18736167950633	0.517422253407174	0.269751583342324	NA	NA	0.950184301865219	0.0174748248379805	72.9756671857407
a3501	gain_cnaOV50	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	4.03340134578915	3.48734115295376	0.546060192835389	1.13288619186175	0.927053346397319	0.575014247282916	0.48200798699648	0.589027799702648	0.269885767446377	NA	NA	0.724538737260399	0.414572057655973	72.9756671857407
a3502	loss_cnaOV35	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.10641683685266	2.24923807611429	0.857178760738367	1.73233027870073	1.19724164304926	0.670232391720109	0.494812548898736	0.715961364787825	0.269886823093928	NA	NA	0.105152651374432	0.339636183851966	72.9756671857407
a3503	loss_cnaOV44	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.74593185612501	3.93775372012917	0.808178135995842	0.502798091014771	1.05814179755403	0.784279207784301	1.60736118620645	0.763771110699908	0.269915698846569	NA	NA	0.099775330974781	0.0794501306285179	72.9756671857407
a3504	loss_cnaOV59	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.59068739728053	0.823078098691927	0.767609298588604	0.985973927341201	1.28019333195677	0.613115577041869	0.778529002950977	0.599604199949484	0.269959517118716	NA	NA	0.956782011882751	0.22722719561379	72.9756671857407
a3505	gain_cnaOV94	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.436333389223294	-0.119218220007574	0.555551609230868	1.30773718973464	0.949155645928277	0.556636474994641	0.424819003077827	0.585311388721222	0.269995992727406	NA	NA	0.179036284699946	0.544330506112463	72.9756671857407
a3506	loss_cnaOV82	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	3.44678575806021	2.33546579340069	1.11131996465952	2.12037700547838	1.36931911890086	0.776223878147551	0.524114325795943	0.811585808829992	0.270066156342953	NA	NA	0.233262167107897	0.461270880662846	72.9756671857407
a3507	loss_cnaOV43_(NF1)	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.5147337587268	1.88921791119074	0.625515847536054	1.27782398103148	0.919992723224007	0.643565970095712	0.48951644109162	0.679913907736146	0.270097106154658	NA	NA	0.466545509794625	0.490976166788332	72.9756671857407
a3508	gain_cnaOV26	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.23160995861387	4.46147419886368	0.770135759750192	0.843184545519084	1.00922154545963	0.770897938713295	0.913365601685784	0.763098809389224	0.270142360490907	NA	NA	0.184929633995744	0.248366204407081	72.9756671857407
a3509	loss_cnaOV36	293	MP470	PDGFR	3	29	2.99573227355399	NA	5.07276454113104	3.94336116061917	1.12940338051188	1.51437825004423	1.76419834250786	0.645869983110452	0.745786847162449	0.64017936832794	0.270155472312607	NA	NA	0.616985855389697	0.324940684349051	72.9756671857407
a3510	loss_cnaOV40	1039	SL 0101-1	RSK, AURKB, PIM3	8	25	2.30258509299405	NA	5.20938120506916	4.85071323909749	0.358667965971671	1.09155685878614	0.707292858485519	0.442716260358134	0.328583859910447	0.507099657049647	0.270210265193002	NA	NA	0.945191153033032	0.405655940107286	72.9756671857407
a3511	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.11559426691979	-2.8657034041203	0.750109137200504	1.1835601225586	1.21276549723764	0.620249805872752	0.633773580998092	0.618511277661721	0.270212759311247	NA	NA	0.366019114598835	0.393095074264428	72.9756671857407
a3512	TP53_mut	1259	BMN-673	PARP1	23	10	2.30258509299405	NA	2.03388449418105	1.5934029852668	0.440481508914255	1.30778921408665	1.52729582085626	0.320319596082813	0.336813841381834	0.288406150857733	0.270224874572143	NA	NA	0.0319110580943237	0.439454255050126	72.9756671857407
a3513	loss_cnaOV82	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	4.08615660540201	2.71566932529292	1.37048728010909	0.55677502832654	1.8802364603201	0.752122054510819	2.46147404316653	0.728890918260233	0.27030160027119	NA	NA	0.339214176929169	0.0187057329663776	72.9756671857407
a3514	loss_cnaOV82	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.43711276071639	4.88771807786138	0.549394682855015	0.984076559072849	0.795817634766392	0.678863443595071	0.558284492999842	0.690352486366159	0.270306313900068	NA	NA	0.945191604931616	0.437483205651185	72.9756671857407
a3515	PIK3R1_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	1.98768417941067	2.47612556317581	-0.488441383765138	1.68999496651342	0.842187349451291	0.498035141129529	0.289019431089092	0.579967609443874	0.270343123339283	NA	NA	0.397448138870954	0.669269843127865	72.9756671857407
a3516	loss_cnaOV41	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-1.24411962526947	-2.12296047603487	0.878840850765399	2.01192594424318	2.02558921407143	0.434246080488829	0.436815705508479	0.433869238965254	0.270555170657325	NA	NA	0.27151996399014	0.40605425449319	73.0023307767456
a3517	loss_cnaOV52, loss_cnaOV53	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	-0.435756608197675	0.316732784302788	-0.752489392500463	0.943365029471323	1.39416083072651	0.577856814583913	0.797665133847679	0.53974360483814	0.270767448476954	NA	NA	0.866285345107412	0.209052379546319	73.0023307767456
a3518	gain_cnaOV96	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	2.48213773624016	1.0691067811045	1.41303095513566	1.28317821258889	2.40326062591871	0.61816417932633	1.10119618714908	0.587964093405599	0.270791474522033	NA	NA	0.356408483315212	0.0835681918486886	73.0023307767456
a3519	gain_cnaOV18_(CCNE1)	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-0.891962322870052	-2.15122176607193	1.25925944320187	1.03908572211593	1.55610052974751	0.825160544315956	1.21189177793492	0.809240418037902	0.270826597223962	NA	NA	0.0351631932166891	0.154044189234223	73.0023307767456
a3520	gain_cnaOV19	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-0.891962322870052	-2.15122176607193	1.25925944320187	1.03908572211593	1.55610052974751	0.825160544315956	1.21189177793492	0.809240418037902	0.270826597223962	NA	NA	0.0351631932166891	0.154044189234223	73.0023307767456
a3521	gain_cnaOV95_(MECOM)	1243	piperlongumine	Increases ROS levels	8	24	2.30258509299405	NA	1.85692898477587	1.53365597889228	0.32327300588358	0.696992387720229	0.666853907161804	0.479628722074359	0.46381138672255	0.484773355020835	0.270968480925193	NA	NA	0.202484142272459	0.273979232273187	73.019831793169
a3522	BRCA1_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.529748525628824	-0.259633082213033	0.789381607841857	1.01975779921776	1.65270037117997	0.493707439839433	0.774087345492602	0.477631409544773	0.27115642286087	NA	NA	0.0956337158637867	0.239473085631287	73.049730992227
a3523	loss_cnaOV85	219	AT-7519	CDK9	7	25	2.32630161961136	NA	0.996788534413245	1.63796507412237	-0.641176539709126	1.03839702740975	1.82466800968537	0.377870411528074	0.617467618631882	0.351393533676125	0.27138894037372	NA	NA	0.309045794152004	0.247433752043962	73.0853022343404
a3524	loss_cnaOV59	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.77692228080474	2.30225193985241	0.474670340952338	0.892222494640116	0.85942092267011	0.550178358796598	0.532008937012734	0.552314155300756	0.271442514917555	NA	NA	0.602579740169085	0.376157474582771	73.0853022343404
a3525	loss_cnaOV44	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.32724699068729	4.90628207446519	-0.579035083777892	1.49643992893827	0.83007325771496	0.649030074581174	0.386941749268024	0.697571061826362	0.271820647323864	NA	NA	0.660513336941482	0.573656885056742	73.1583115110946
a3526	loss_cnaOV83	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.69663695668252	5.12941001735969	0.567226939322835	0.81183155239429	0.692227931445389	0.794930462749113	0.698700287824419	0.819422206986724	0.27187102356377	NA	NA	0.117541665019409	0.265497950738379	73.1583115110946
a3527	loss_cnaOV102	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.62962762837238	3.82831096285981	0.801316665512573	1.12561776531723	1.05214615775645	0.75807573765815	0.711890563744557	0.761602045120109	0.271981502559224	NA	NA	0.309602683888207	0.342271897964565	73.1583115110946
a3528	loss_cnaOV58	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.36776922098119	2.52784932351021	0.839919897470979	1.67083499821146	1.69115247235137	0.497422394093523	0.502694699578396	0.496655334869457	0.272022090138172	NA	NA	0.635241873731532	0.344144328627927	73.1583115110946
a3529	loss_cnaOV33_(ZFHX3)	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.67418944829454	4.27826809520754	0.395921353086998	0.500704732886578	0.584350249532585	0.687052646527229	0.790728201837637	0.677541172274148	0.272347810520214	NA	NA	0.246934864723865	0.217619246642845	73.189305417056
a3530	loss_cnaOV36	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.60366938213205	-2.84892575055796	1.24525636842591	2.19778265696679	1.70637084921835	0.714249958279626	0.56659668529031	0.729768894608305	0.272356372581806	NA	NA	0.691985218498595	0.431550860801169	73.189305417056
a3531	SMAD4_mut	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.08669172203689	3.77571617565497	1.31097554638192	2.27846067058405	1.62966262191644	0.779202110667285	0.575377737832916	0.8044459808744	0.272410451117624	NA	NA	0.141364455451044	0.42523996388466	73.189305417056
a3532	TP53_mut	1003	Camptothecin	TOP1	21	10	-2.30258509299405	NA	-3.48681164015509	-4.12031606410389	0.633504423948795	1.86336120159934	1.33341214914933	0.369068840092619	0.339979400346563	0.475100233902134	0.272607551561321	NA	NA	0.238153464332213	0.290176711625627	73.189305417056
a3533	loss_cnaOV39	1243	piperlongumine	Increases ROS levels	9	23	2.30258509299405	NA	1.8839999357397	1.50900764999845	0.374992285741248	0.770147321089702	0.625261425173801	0.562222366449725	0.486909809944753	0.599736799110889	0.272689829208472	NA	NA	0.202550885933856	0.216527509540269	73.189305417056
a3534	loss_cnaOV59	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.65485702675936	1.83712808901408	0.817728937745278	0.898783242646776	1.36292517875108	0.617688111974684	0.909817739077104	0.599980799015399	0.272759554257956	NA	NA	0.836692207969578	0.172655239545233	73.189305417056
a3535	gain_cnaOV48_(SOX17)	219	AT-7519	CDK9	3	29	2.32630161961136	NA	0.588150754937331	1.5917998044531	-1.00364904951577	1.53233471801472	1.70282377534268	0.593175869775058	0.6549802975267	0.589402769710444	0.272760549781825	NA	NA	0.309103313297133	0.376261818521468	73.189305417056
a3536	SMARCA4_mut	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	3.6696569071868	4.53245328312236	-0.862796375935568	1.01672692508749	0.953388739536987	0.900865501354049	0.848601875927823	0.904978567666517	0.272782972164057	NA	NA	0.0290543537292691	0.275802120610832	73.189305417056
a3537	loss_cnaOV82	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	2.62935999788549	3.37207028132065	-0.742710283435162	1.3015017580477	1.07710511994977	0.679205610090523	0.57065638124781	0.689542988589453	0.272831561628891	NA	NA	0.950197871945299	0.429058244220332	73.189305417056
a3538	TP53_mut	153	Midostaurin	KIT	12	7	-0.669430653942629	NA	0.387001604460475	-0.341220473467863	0.728222077928338	1.29308802292047	1.30233356796082	0.561744281038745	0.563165124895079	0.559167095008219	0.273094110788601	NA	NA	0.866335302292199	0.260242950027735	73.2390298443789
a3539	NF1_mut	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	3.91751806367614	3.15593142889142	0.761586634784725	0.762584276827307	1.09298035188424	0.715396936381777	0.998691761588984	0.696798102062664	0.273195491124152	NA	NA	0.0588154784349183	0.139731553735399	73.2455157445203
a3540	gain_cnaOV96	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.69226828067984	3.61741530606525	1.07485297461459	1.07348363247205	1.57207727233079	0.702087129111567	1.00127560598142	0.683715103279238	0.273456980479336	NA	NA	0.159408877122874	0.138978719758916	73.2684097718401
a3541	gain_cnaOV96	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.61013072946712	2.90049325349123	0.709637475975892	1.21683098536693	0.957745162158363	0.71986062304218	0.583184915990533	0.740946030337195	0.27346735086626	NA	NA	0.083484580706814	0.333223765214498	73.2684097718401
a3542	loss_cnaOV56	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	2.21078596668164	2.84866101245184	-0.637875045770203	1.43227147129256	1.20766163247893	0.521174366708732	0.445359038810256	0.528190205447578	0.273579542310255	NA	NA	0.090224952219716	0.525105587179317	73.2684097718401
a3543	gain_cnaOV19	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	2.17240085645496	1.22066648171624	0.951734374738717	0.619597287982889	1.22478171057134	0.797085834309128	1.53605316420462	0.777064489552792	0.273589761843858	NA	NA	0.0928793603983446	0.0898678196506505	73.2684097718401
a3544	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	2.4537049057678	1.40076736121152	1.05293754455627	0.628128667660002	1.68601063309897	0.663786286344743	1.67630869082736	0.624514177956829	0.273746204496508	NA	NA	0.0747254138769068	0.0251614220157163	73.2882185398255
a3545	loss_cnaOV20	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.69961318114369	3.86149191453963	0.838121266604064	0.76413116159355	1.1766125012102	0.734627765543572	1.09682906381702	0.712317152624177	0.273818210635851	NA	NA	0.0784959844501858	0.113480034984439	73.2882185398255
a3546	gain_cnaOV49	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.0577070111509	3.74597715498999	-0.688270143839093	0.69791078076256	1.06153123920467	0.66100503968927	0.986186433582622	0.648374836669679	0.273960319182781	NA	NA	0.828529606151664	0.220770401438776	73.2922783643076
a3547	PTEN_mut	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	2.42345096985439	0.680462969300686	1.7429880005537	3.13420568963203	1.91125403432517	0.86146973400467	0.556117936458197	0.911960403614854	0.274084881283798	NA	NA	0.408696521150966	0.438132233086935	73.2922783643076
a3548	KRAS_mut	345	KIN001-270	CDK9	7	25	2.99573227355399	NA	4.85118380815943	5.28589170490175	-0.434707896742318	0.841820514399718	0.731992834646864	0.575591246506376	0.516390239138206	0.593869060141873	0.274102966949548	NA	NA	0.326647376641167	0.246925426644257	73.2922783643076
a3549	loss_cnaOV35	1061	SB590885	BRAF	5	28	1.6094379124341	NA	3.29415475280365	4.04064430130132	-0.746489548497669	2.06167424501914	1.0977654341998	0.590512626395166	0.362079290800249	0.680008246972919	0.274142358718993	NA	NA	0.567722440143003	0.46987819276711	73.2922783643076
a3550	loss_cnaOV59	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.77693903571993	-4.77770623729284	1.00076720157291	2.1301461960111	1.27785125098746	0.71973772674094	0.469811510330579	0.783164081734525	0.274379396612581	NA	NA	0.129805786762213	0.421333359049103	73.3245982792006
a3551	loss_cnaOV102	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.57353362833006	3.40295308554798	-0.829419457217921	1.16492686626052	1.21882069748154	0.682480047563039	0.711992727818531	0.680509823086985	0.274437018395299	NA	NA	0.993517559678889	0.342626717931145	73.3245982792006
a3552	PIK3R1_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	2.14035508490623	2.94105717708362	-0.800702092177392	0.848345231082575	1.6227231573475	0.51833011844921	0.94383991662877	0.493431112110473	0.274512414165921	NA	NA	0.968368773750666	0.130916010046874	73.3245982792006
a3553	loss_cnaOV85	1058	GDC0941	PI3K (class 1)	7	26	1.38629436111989	0.693147180559945	1.45980824238897	0.678041857966034	0.781766384422932	0.902266215230158	1.39699397044693	0.59412059154831	0.866447586340704	0.559606126412147	0.274623266682678	NA	NA	0.157607259222681	0.0944560179401605	73.3245982792006
a3554	loss_cnaOV16, loss_cnaOV17	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-1.2329824349646	-2.79171834017413	1.55873590520953	3.52996058862279	1.60973423693004	0.804675931578315	0.441573175132152	0.968318787939941	0.274830790554987	NA	NA	0.332511386262747	0.526270162268998	73.3245982792006
a3555	RB1_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.57640667921212	-2.37043938406998	0.794032704857856	1.37267584009173	1.62682125968457	0.492687786641883	0.578456094051158	0.488088473230189	0.274837447546395	NA	NA	0.119287452581995	0.426925185200089	73.3245982792006
a3556	NF1_mut	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.81243078017132	4.47384396620014	0.338586813971174	0.899082247314553	0.548458407456116	0.571044282107233	0.37659159101683	0.617342736237051	0.274848104100667	NA	NA	0.609895644796041	0.511328108592386	73.3245982792006
a3557	gain_cnaOV48_(SOX17)	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	1.770513761528	2.43997363436265	-0.669459872834657	1.74632003644559	1.26628582564131	0.513939238881065	0.383354630802527	0.528679907236274	0.274881480267482	NA	NA	0.105294270934406	0.578155656160516	73.3245982792006
a3558	loss_cnaOV84	206	Ruxolitinib	JAK1, JAK2, TYK2	6	26	1.65632149833295	0.0237165266173161	4.70814018947127	4.3928096035847	0.315330585886572	0.638321319865175	0.526162229125548	0.577046197111893	0.493999771076384	0.599302968612234	0.275018285844511	NA	NA	0.357965969817606	0.299480919715574	73.3303336725162
a3559	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.46010826721186	3.80134537267329	0.658762894538573	1.08672068471055	1.05098972618739	0.624024610559807	0.606193388795241	0.626802411217018	0.275057551416934	NA	NA	0.309726571842981	0.260911453208242	73.3303336725162
a3560	loss_cnaOV55	287	KIN001-244	PDPK1 (PDK1)	7	25	2.99573227355399	NA	3.84685445347092	3.45967777408425	0.387176679386662	0.894625719410591	0.896951117136268	0.431882321360979	0.432780626563862	0.43165861772135	0.275204745198455	NA	NA	0.658667739612283	0.336439120044285	73.3399594607543
a3561	loss_cnaOV1	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	3.18596373352066	2.83043666620309	0.355527067317568	0.882419665050692	0.796838766452978	0.44284336497931	0.402900208822005	0.446171901123924	0.275248247576632	NA	NA	0.0179247415317836	0.562608846585417	73.3399594607543
a3562	SMARCA4_mut	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	3.96698621936799	4.54547187666762	-0.578485657299636	0.595636245997891	0.663397566546439	0.877892571585645	0.971206270918717	0.872004490928654	0.275386457711874	NA	NA	0.05012413670926	0.227153058745427	73.3561856997163
a3563	loss_cnaOV43_(NF1)	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.71954439675399	4.19616170140108	0.523382695352913	1.17256045433595	0.827870864008929	0.59363980010567	0.446358815374956	0.632203303808102	0.275664246536043	NA	NA	0.515527942636375	0.385471499659887	73.3928482814514
a3564	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1058	GDC0941	PI3K (class 1)	8	25	1.38629436111989	0.693147180559945	1.31481212900937	0.693169958870586	0.621642170138786	1.14233558661689	1.37792679226856	0.467968032753889	0.544185244180149	0.451143103992731	0.275739319299212	NA	NA	0.157644948264017	0.2240984753687	73.3928482814514
a3565	gain_cnaOV94	263	FR-180204	ERK	7	25	2.99573227355399	NA	5.06885136264343	4.73978112097399	0.329070241669441	0.848335018021987	0.710596654216711	0.444570780020505	0.38790128272285	0.463090052164929	0.275877674845434	NA	NA	0.761892290257256	0.373984464281511	73.3928482814514
a3566	loss_cnaOV34	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	-0.0937928996953711	0.452810763089103	-0.546603662784474	0.981016227376225	0.889269488889839	0.607881293417284	0.557181061363676	0.614665936044711	0.275884332148835	NA	NA	0.908293691758226	0.355458454984982	73.3928482814514
a3567	gain_cnaOV48_(SOX17)	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	-0.26470125202477	0.335706606960476	-0.600407858985246	1.56603538589562	1.09814197902151	0.529381477985677	0.383393545505277	0.546748845281585	0.275910847472821	NA	NA	0.14139674848357	0.57790091023558	73.3928482814514
a3568	NF1_mut	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	4.07288975052747	3.48169995227685	0.591189798250614	0.369257114046265	0.990064750246159	0.624613824306256	1.60102480294135	0.597122358011056	0.276022800987728	NA	NA	0.724680950326037	0.0458969935781657	73.4020500539523
a3569	loss_cnaOV102	272	AR-42	HDAC	3	27	1.63315443905142	NA	1.3079984346626	0.182553257175587	1.12544517748702	1.23809804809812	1.86410486435887	0.616169342046686	0.909011349477411	0.603745636313274	0.276379480567822	NA	NA	0.479322511522798	0.25080236946555	73.4220200127695
a3570	gain_cnaOV72_(ASXL1)	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	5.02148571462763	4.50824302230395	0.513242692323672	0.866982619699993	0.942290051587456	0.550335009084215	0.591987290934704	0.544675911052041	0.27650927830685	NA	NA	0.94231647713789	0.27645106191134	73.4220200127695
a3571	loss_cnaOV40	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	NA	1.51682991620195	1.11981279851654	0.39701711768541	1.34134640180038	1.20404129691621	0.321112735488434	0.295984033022734	0.329737126710065	0.276559182519303	NA	NA	0.260433497338723	0.471239979911237	73.4220200127695
a3572	ARID1A_mut	1072	BMS-708163	g-secretase	9	24	1.6094379124341	NA	3.66009980724976	3.90935476182079	-0.249254954571027	0.640989946593825	0.929275593855671	0.288444096070717	0.388859382109735	0.26822500904908	0.276675050852293	NA	NA	0.922679200258519	0.392845887370513	73.4220200127695
a3573	loss_cnaOV1	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.45158546573841	3.73368453884717	0.717900926891233	1.1815314494496	1.00418710773432	0.705919589978356	0.607602046670581	0.714907532034526	0.276717365476793	NA	NA	0.713275977035485	0.4043830986694	73.4220200127695
a3574	PIK3R1_mut	170	Shikonin	unknown	3	15	2.77258872223978	NA	-0.380391583541672	0.0625410755595438	-0.442932659101216	0.42972414744091	0.821832670746637	0.565236621749291	1.03073718742353	0.538957229211648	0.276874150478743	NA	NA	0.573535380310919	0.227261757696125	73.4220200127695
a3575	loss_cnaOV20	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.25110454464868	0.666997701796696	0.584106842851986	0.483833733259529	1.09395077017517	0.565106092815122	1.20724704107944	0.533942530849406	0.277000241612316	NA	NA	0.76872326702442	0.0745392781226335	73.4220200127695
a3576	gain_cnaOV51_(MYC)	1502	Bicalutamide	ANDR (androgen receptor)	8	24	2.30258509299405	NA	4.7365586628119	4.44270353632475	0.293855126487151	0.664370004373057	0.564925989973423	0.498370688722956	0.442306432489306	0.520165706132543	0.277016379463256	NA	NA	0.609962535091366	0.286243479091836	73.4220200127695
a3577	gain_cnaOV72_(ASXL1)	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.63582528459543	4.15673503086301	0.479090253732424	0.778891816692902	0.995476502185416	0.493779906307394	0.615092164874184	0.481267265154582	0.277070529885723	NA	NA	0.203445970560068	0.267820928159117	73.4220200127695
a3578	loss_cnaOV16, loss_cnaOV17	333	T0901317	LXR	6	26	2.32630161961136	NA	5.34840366676656	4.61603207863444	0.732371588132114	0.970377657745171	1.11182304438867	0.672193616322305	0.754728411445393	0.658712365990583	0.277080841633047	NA	NA	0.00457854171677065	0.142461249656204	73.4220200127695
a3579	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.96884211530489	2.40279376097977	0.566048354325122	1.12141710144616	0.68735852236906	0.753174073848583	0.504761657009827	0.823512527893262	0.277087452522511	NA	NA	0.742782242671465	0.477160479792135	73.4220200127695
a3580	gain_cnaOV51_(MYC)	228	KIN001-102	AKT1	8	24	2.32630161961136	NA	2.53730406248334	2.87271228172007	-0.335408219236733	1.22710210424966	1.23058976368745	0.272739087734852	0.273333586565583	0.272558921855229	0.277098113182238	NA	NA	0.0903186557495432	0.516058567275556	73.4220200127695
a3581	loss_cnaOV20	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	1.63549830109467	2.39668646457352	-0.761188163478851	1.2250587663775	1.24123244831377	0.614074815596574	0.621348284972225	0.613251905002106	0.277189770768171	NA	NA	0.842216477678003	0.311811088646738	73.4220200127695
a3582	gain_cnaOV51_(MYC)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	8	25	0.693147180559945	NA	2.13660760387391	1.61016632719603	0.526441276677871	1.28756751994481	1.80124259526537	0.30987511631277	0.408864986513824	0.292265616003998	0.277231781512862	NA	NA	0.22298278645258	0.377458402423216	73.4220200127695
a3583	loss_cnaOV81_(RB1)	1028	VX-702	p38	3	28	0.693147180559945	NA	3.93062467571101	3.26229185155484	0.668332824156177	0.437358491127321	0.936534172282966	0.733679530811823	1.52811214990591	0.713623532312759	0.277258621953777	NA	NA	0.511875367281657	0.0903049818827535	73.4220200127695
a3584	loss_cnaOV54	1058	GDC0941	PI3K (class 1)	11	22	1.38629436111989	0.693147180559945	1.32342994356587	0.604091664755229	0.719338278810645	0.934559678967945	1.4559616217408	0.548849001673831	0.769708232656717	0.494064038549711	0.277337664198137	NA	NA	0.157698598010917	0.0969306147992979	73.4224596264765
a3585	TP53_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	23	10	0	NA	-1.71235572975347	-2.62793096709937	0.9155752373459	2.08547080446756	1.78651407260643	0.457038469772324	0.439025679661651	0.512492597391143	0.277566987465092	NA	NA	0.271798249897322	0.213760801393547	73.4626733419217
a3586	loss_cnaOV35	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.90646043723337	3.40595516438878	0.50050527284459	1.12170440187904	0.854517636598976	0.560166166162094	0.446200685319734	0.585716726499206	0.277851572923385	NA	NA	0.791418537691311	0.387008737296455	73.5174865993638
a3587	PTEN_mut	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-1.63417404589806	-0.617112195109787	-1.01706185078827	0.900931000500827	0.862020093911602	1.17462337384208	1.1289009371671	1.17985863435403	0.277953234475916	NA	NA	0.0393518738806622	0.104138085491207	73.5238824651985
a3588	loss_cnaOV81_(RB1)	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.84812912384405	4.24081225990011	0.607316863943935	0.440242878046317	0.806238961834839	0.772191271441762	1.37950411972375	0.753271539447564	0.278210221066935	NA	NA	0.218445224891962	0.116239392622888	73.5556505447481
a3589	gain_cnaOV51_(MYC)	219	AT-7519	CDK9	8	24	2.32630161961136	NA	1.05837870376357	1.64415070682681	-0.585772003063242	1.0418490402644	1.85292782379651	0.344840343577108	0.562242686248083	0.316133200408767	0.278228377126829	NA	NA	0.30932905925628	0.279151642938444	73.5556505447481
a3590	loss_cnaOV57_(ZNRF3)	1030	KU-55933	ATM	4	29	2.30258509299405	NA	4.724910953991	4.07183388832238	0.65307706566862	1.09340205207664	1.00586652094152	0.64363633771942	0.597289043337962	0.64926812064221	0.278430919351219	NA	NA	0.524029413741615	0.325606929845204	73.5744172751422
a3591	TP53_mut	1230	IOX2	EGLN1	22	10	-2.30258509299405	NA	0.0700431025955082	-0.356871340700103	0.426914443295611	0.947095539261411	0.958882443428598	0.449077799831818	0.450761750634512	0.445220836215468	0.278499138526043	NA	NA	0.543255383215312	0.25714432906079	73.5744172751422
a3592	gain_cnaOV26	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	6.02902314731033	5.68259585790616	0.346427289404167	0.387630305758616	0.475860405970365	0.7363063269076	0.893705379217417	0.728001920432399	0.278604138177805	NA	NA	0.375021025661236	0.256189098280766	73.5744172751422
a3593	loss_cnaOV85	1043	JNK Inhibitor VIII	JNK	7	26	2.30258509299405	NA	4.87075619639295	4.3266115333519	0.544144663041049	0.917964153684195	1.00850984447897	0.548737416523158	0.592773324379995	0.539553149649395	0.278706475687653	NA	NA	0.368440069192841	0.202163413724667	73.5744172751422
a3594	loss_cnaOV52, loss_cnaOV53	134	Etoposide	TOP2	5	14	2.77258872223978	NA	1.40168749335933	2.59817625770624	-1.19648876434691	1.202361048061	1.90834133454765	0.676832083932684	0.995116039625898	0.62697838310489	0.278873539245176	NA	NA	0.397004926045123	0.133385960737985	73.5744172751422
a3595	loss_cnaOV58	1020	Lenalidomide	TNFA	5	26	1.6094379124341	NA	4.8416568816362	4.31497640368411	0.526680477952088	0.597993042640457	0.774030705962832	0.700183967468515	0.880746832147937	0.680438739567754	0.27905399005568	NA	NA	0.0402929742477299	0.131247134441471	73.5744172751422
a3596	SMAD4_mut	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	7.71414413005755	8.86929765386482	-1.15515352380727	1.70985238552658	1.68520985038309	0.684770417447974	0.675586696012662	0.685465684611727	0.279092313067413	NA	NA	0.920637811067991	0.363162964757409	73.5744172751422
a3597	loss_cnaOV84	1371	PLX4720 (rescreen)	BRAF	6	27	2.30258509299405	NA	4.99070575136143	4.4255142708966	0.565191480464827	0.827197381658559	0.995687113004765	0.582376291774606	0.683260722285653	0.567639646112526	0.279150966401317	NA	NA	0.31897945812451	0.181138288541512	73.5744172751422
a3598	loss_cnaOV54	1039	SL 0101-1	RSK, AURKB, PIM3	11	22	2.30258509299405	NA	5.14647683967346	4.83325615370829	0.31322068596517	0.636470438603568	0.882530046543553	0.386048434229529	0.492121341334225	0.354912206323066	0.279158748362194	NA	NA	0.945232396000218	0.254138992406327	73.5744172751422
a3599	BRCA1_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.2923863324607	2.72965656533515	0.562729767125549	0.753474248068135	0.97012999182575	0.59152384470799	0.746846715157626	0.580056045959895	0.279393689828848	NA	NA	0.965727789515026	0.241613096396484	73.5744172751422
a3600	loss_cnaOV81_(RB1)	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	4.45803081000262	3.40330610497193	1.05472470503069	1.46869800096971	1.70733491175017	0.626240362567676	0.718135862058982	0.617760872674653	0.279427785856041	NA	NA	0.694305763847663	0.25546179774983	73.5744172751422
a3601	TP53_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	21	10	1.6094379124341	NA	1.53423280230015	0.931794155599601	0.602438646700547	1.34472346020563	1.30326427133484	0.452282991229232	0.448001886282569	0.462253634931241	0.279525560567293	NA	NA	0.57529550085998	0.248944701418282	73.5744172751422
a3602	gain_cnaOV4_(KRAS)	1032	Afatinib	ERBB2, EGFR	5	26	-0.693147180559945	NA	1.10913926327853	0.212472092563027	0.896667170715504	1.41039473860164	1.69089147059203	0.541782698437602	0.635756179581698	0.530292562420672	0.279678410785113	NA	NA	0.834841833830254	0.251994719241263	73.5744172751422
a3603	loss_cnaOV20	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-3.78458864324476	-4.77657296210398	0.991984318859219	1.82451740961942	1.33218229715435	0.713033587452331	0.543696822858018	0.744631062113779	0.279749597699664	NA	NA	0.129982617998944	0.362186332800508	73.5744172751422
a3604	gain_cnaOV18_(CCNE1)	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.87399123995741	3.22079118543306	0.653200054524347	1.16434090453171	1.08545030107726	0.59729585645252	0.561004128586431	0.601777947710805	0.27989743006659	NA	NA	0.95022827680564	0.352757961103455	73.5744172751422
a3605	loss_cnaOV54	1006	Cytarabine	DNA synthesis	10	21	0.693147180559945	NA	0.264315942454533	-0.290178462554379	0.554494405008912	1.26495825939669	1.23121212733751	0.446530763848823	0.438349962055959	0.450364638795431	0.279902091656248	NA	NA	0.763804957004043	0.265450850689952	73.5744172751422
a3606	loss_cnaOV52, loss_cnaOV53	1375	Temozolomide	DNA akylating agent	9	24	3.40119738166216	NA	6.166520471508	5.86498567712816	0.301534794379843	0.59925310835514	0.724827094000658	0.434114319459965	0.503184364295599	0.416009275695714	0.279971887550252	NA	NA	0.907449143159215	0.241356527078431	73.5744172751422
a3607	loss_cnaOV59	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	3.88621152162614	2.88464350236252	1.00156801926362	1.10814653534436	1.64552755264023	0.626006457919881	0.903822723185597	0.6086607408406	0.280098352067386	NA	NA	0.658984611208	0.1742865379793	73.5744172751422
a3608	loss_cnaOV52, loss_cnaOV53	345	KIN001-270	CDK9	8	24	2.99573227355399	NA	5.49234725079375	5.09028338638791	0.402063864405843	0.718667416574521	0.76782068012738	0.531382595663249	0.559457483577386	0.523642921859231	0.280188449603632	NA	NA	0.326897035638322	0.201455348369532	73.5744172751422
a3609	loss_cnaOV33_(ZFHX3)	1248	FK866	NAMPT	4	28	0	NA	0.0222016007313435	-1.95558051351853	1.97778211424987	3.11919722326686	2.64614453277339	0.733276150366413	0.634067669558407	0.747420290068958	0.280203158007897	NA	NA	0.0418286072542153	0.299695086253665	73.5744172751422
a3610	loss_cnaOV55	211	TL-2-105	CRAF	7	25	2.32630161961136	1.63315443905142	4.68036886269806	4.33320886875214	0.347159993945917	0.834747133960886	0.553075706838896	0.560172515174798	0.415886416163705	0.627689825557717	0.280251739361239	NA	NA	0.264532869701513	0.331260471722052	73.5744172751422
a3611	gain_cnaOV4_(KRAS)	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.12331391947576	1.6732626059677	-0.549948686491947	0.602679343890631	1.33104781810958	0.438839911720382	0.912506280606402	0.413169744174188	0.280353879586119	NA	NA	0.155700787684713	0.227506573072897	73.5744172751422
a3612	loss_cnaOV33_(ZFHX3)	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	5.06482839060666	4.52038130760422	0.544447083002432	0.928026597882954	0.934571107430283	0.582970521104951	0.586671852126268	0.582563572395744	0.280386205642886	NA	NA	0.942335610930128	0.335523857845389	73.5744172751422
a3613	gain_cnaOV95_(MECOM)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	8	25	-2.30258509299405	NA	0.142558035920923	-0.48460655313955	0.627164589060473	0.719983525506746	1.53273101388226	0.450761714130277	0.87108186068432	0.409181117482531	0.280409725473289	NA	NA	0.887460966856759	0.127560368834123	73.5744172751422
a3614	loss_cnaOV16, loss_cnaOV17	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	2.19858923713076	1.44369313414399	0.754896102986771	0.964188425060608	1.03552328382394	0.735703175181448	0.782934210125287	0.728999641803436	0.280544635408783	NA	NA	0.277824138806659	0.223271091971213	73.5744172751422
a3615	PIK3R1_mut	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	-0.398145018498441	0.402422126615435	-0.800567145113876	0.908652380360646	1.1359128536229	0.721746364936685	0.881048861387596	0.704778665511649	0.280601777645997	NA	NA	0.141546008395155	0.128552566437926	73.5744172751422
a3616	loss_cnaOV38	279	BIX02189	MAP2K5 (MEK5)	8	24	2.99573227355399	NA	4.15721270458564	4.52250646030791	-0.365293755722276	0.65180560325304	0.746820907568562	0.503322961231208	0.560433592315198	0.489131667338518	0.280662695448056	NA	NA	0.518536921582935	0.207844978636333	73.5744172751422
a3617	loss_cnaOV83	333	T0901317	LXR	5	27	2.32630161961136	NA	5.3923764362143	4.63501384681568	0.757362589398618	0.704549586976895	1.14053451217164	0.693236458352022	1.07495995086497	0.664041799100455	0.28073799619365	NA	NA	0.00458963677127505	0.0818645124122525	73.5744172751422
a3618	gain_cnaOV49	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	0.765953549907894	1.36616103066938	-0.600207480761489	1.19482265281991	1.21594081878733	0.494183249332963	0.502340225425871	0.49361570192214	0.280761213141333	NA	NA	0.0930718579647586	0.481075217950098	73.5744172751422
a3619	gain_cnaOV50	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.00024580621706	4.502972759208	-0.502726952990935	0.994362484728119	1.00466024646406	0.500889536627332	0.505577151905919	0.500394989012753	0.280799061943764	NA	NA	0.368521462471728	0.398728223125659	73.5744172751422
a3620	loss_cnaOV41	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	9.50781806176875	8.61321832267477	0.894599739093985	1.87224918773602	1.65847759063237	0.529483009452407	0.477820871790982	0.539410206171602	0.28082370286816	NA	NA	0.920649892717662	0.362715782334403	73.5744172751422
a3621	PIK3CA_mut	329	QL-XI-92	DDR1	6	26	2.32630161961136	NA	3.9273913141154	4.67358591377676	-0.746194599661359	0.853548978739286	1.00391359923037	0.761069285461617	0.874225871330205	0.743285677406318	0.280942454923243	NA	NA	0.185329557731247	0.0969666431952502	73.5744172751422
a3622	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.8630941309381	2.93361917753011	0.929474953407989	1.34201843584709	1.15470806226039	0.79538136244639	0.692594772605564	0.804943676922548	0.280947930632691	NA	NA	0.0842141441180117	0.35289699546298	73.5744172751422
a3623	gain_cnaOV50	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	2.23181169883669	3.12098633418959	-0.889174635352898	1.68735513549651	1.59856166327242	0.553085656931502	0.526963539949317	0.556234179626618	0.280998665405361	NA	NA	0.659008950419551	0.379819544823045	73.5744172751422
a3624	PTEN_mut	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.21009227947624	4.92730232571393	-0.717210046237692	0.306458599893454	0.602124937368347	1.22168770614342	2.34031626616791	1.19113161028065	0.281034142367813	NA	NA	0.0467174308360049	0.0280119650647138	73.5744172751422
a3625	loss_cnaOV44	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.76537551386901	1.85389269164913	0.911482822219878	0.312803628744211	1.36883214040782	0.687973075440285	2.91391383750611	0.665883562573508	0.281113802947265	NA	NA	0.836808198061314	0.0112022361817135	73.5744172751422
a3626	loss_cnaOV83	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	2.31791139280754	1.42176840105575	0.896142991751798	0.822857083799045	1.27572471250872	0.7337292615848	1.08906274175146	0.702457969940493	0.281272109455671	NA	NA	0.155745504680084	0.122280420363576	73.5744172751422
a3627	loss_cnaOV81_(RB1)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.37053897069851	-0.429546738755704	0.800085709454213	0.578481942725355	1.45333024613911	0.574405853868411	1.38307810557549	0.550518859412517	0.281304649556514	NA	NA	0.887469160181667	0.0715312363850573	73.5744172751422
a3628	loss_cnaOV35	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	0.575033528434812	1.59822039353355	-1.02318686509874	1.00450548578818	1.85584069686779	0.580357764326726	1.01859758814149	0.551333348183188	0.281323513566515	NA	NA	0.609494986949494	0.106415358314833	73.5744172751422
a3629	ARID1A_mut	254	AC220	FLT3	8	24	0.0237165266173161	NA	2.69451332489525	2.44958818171265	0.244925143182599	0.318494083453631	0.691930606653738	0.391830369705812	0.769010025325186	0.353973564440352	0.281609495169414	NA	NA	0.856128551424767	0.186593614499443	73.6022522661972
a3630	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	5.06791615801015	3.77772784322927	1.29018831478088	2.42682961231544	1.615399092193	0.766163414252733	0.53163531062649	0.798680846743189	0.281615897420183	NA	NA	0.141679679809571	0.45591066850865	73.6022522661972
a3631	loss_cnaOV82	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.61695740788358	3.82957798490869	0.787379422974887	1.1365908212489	1.05232214956784	0.744242101600013	0.692755394689628	0.748230400071158	0.281662660041307	NA	NA	0.309986811438013	0.352893739158757	73.6022522661972
a3632	PTEN_mut	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.58433565777331	4.03226563266915	0.55207002510416	0.995077287826513	1.12545550659726	0.494138655320101	0.554801151486447	0.490530298059766	0.281758752830731	NA	NA	0.817140931657053	0.443247520717482	73.6070907572797
a3633	loss_cnaOV16, loss_cnaOV17	288	KIN001-055	JAK3, MNK1	6	26	2.32630161961136	NA	4.23680824100183	3.70041379145278	0.536394449549051	0.995712801832071	1.02114340021309	0.52745455354959	0.538703980266305	0.52528807358214	0.281910740408454	NA	NA	0.713397206766759	0.272087923418775	73.6265246060738
a3634	loss_cnaOV56	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	2.32194894093212	3.48404784366619	-1.16209890273408	2.12623167715539	1.60599532254697	0.706098926142741	0.546553282607851	0.723600427983243	0.282411158372441	NA	NA	0.624991939163192	0.445568013151694	73.7369221542777
a3635	loss_cnaOV20	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.18040780125163	4.45150980560859	-0.271102004356956	1.0052688447509	0.548740240799698	0.430967670445022	0.269681096527101	0.494044329538999	0.28255741090616	NA	NA	0.264624051600575	0.585668318979836	73.7548125981892
a3636	loss_cnaOV87, loss_cnaOV88	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	2.15921414828313	1.22203062394091	0.937183524342225	0.767840219278269	1.2198638229116	0.78421460219455	1.2205449790363	0.768268971290037	0.282809863685362	NA	NA	0.09312575175095	0.15148131190319	73.7600657226039
a3637	loss_cnaOV35	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	4.53044975372836	5.02438202535502	-0.493932271626666	1.79852460977308	0.629733114838331	0.604852592068078	0.274631922711908	0.784351751540764	0.282958010728873	NA	NA	0.445010502433969	0.68232868691805	73.7600657226039
a3638	loss_cnaOV52, loss_cnaOV53	1495	AZD-2281	PARP1, PARP2	9	24	2.30258509299405	NA	3.3940514080235	3.62393070433911	-0.229879296315615	0.960942971973592	0.903336597036256	0.250263595013165	0.239222620925659	0.254478006392991	0.282981119461579	NA	NA	0.137777938559083	0.544202674474963	73.7600657226039
a3639	gain_cnaOV4_(KRAS)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	0	NA	-1.2647660159125	-2.18500497476678	0.92023895885428	2.64232745091314	1.82961818285183	0.457217734174608	0.34826832629554	0.502967759874305	0.283205727447787	NA	NA	0.272015729892511	0.412331401558238	73.7600657226039
a3640	loss_cnaOV42	306	TG101348	JAK2	4	28	2.32630161961136	NA	3.57817612032886	2.71632754651738	0.861848573811478	1.0533494177214	1.40871422599595	0.62574773021803	0.818198177463106	0.611798019716994	0.283221762022647	NA	NA	0.622676742078374	0.207672906275107	73.7600657226039
a3641	loss_cnaOV34	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.65122901595118	2.22528482072949	0.425944195221688	0.797116115813804	0.908217186844683	0.476599897251175	0.534356521931345	0.468989357822546	0.283271865365978	NA	NA	0.589106891370043	0.325063231742978	73.7600657226039
a3642	loss_cnaOV55	205	BMS-708163	g-secretase	7	25	2.32630161961136	0.940007258491471	5.34062299841884	4.98399142820463	0.356631570214212	0.528744443989968	0.621097582540519	0.590686139032288	0.674487598437968	0.574195714553351	0.283548633833508	NA	NA	0.105910273071857	0.15752460671247	73.7600657226039
a3643	loss_cnaOV40	172	Embelin	XIAP	4	15	3.46573590279973	NA	3.5292671416447	2.98297249904957	0.54629464259513	1.12102673692178	0.897882120002705	0.580477155199424	0.487316336535557	0.608425794906669	0.283657941613462	NA	NA	0.662988383206705	0.417673619566526	73.7600657226039
a3644	ARID1A_mut	256	JW-7-24-1	LCK	8	24	2.32630161961136	NA	1.54254038090435	2.07161214800821	-0.529071767103862	0.865833934933732	1.4444931687561	0.397156816353132	0.61105455186895	0.366268099114282	0.283769088178551	NA	NA	0.836844140760465	0.2271742311759	73.7600657226039
a3645	PIK3R1_mut	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-0.958207593032215	-1.68740805606471	0.729200463032497	0.292103425233197	1.3798095895113	0.56093547614612	2.49637765271102	0.528479051439818	0.283824552690331	NA	NA	0.61310704219511	0.0755973275570626	73.7600657226039
a3646	loss_cnaOV58	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	6.41347391027167	5.73794323410516	0.675530676166511	0.386648815751518	1.33939091536831	0.529194230671293	1.7471427524057	0.5043566209203	0.283879169217681	NA	NA	0.565650849518675	0.0492456846624042	73.7600657226039
a3647	gain_cnaOV48_(SOX17)	1248	FK866	NAMPT	3	29	0	NA	-2.82585325136825	-1.59275476625823	-1.23309848511003	3.67036660894523	2.67833841839942	0.447487072457743	0.335960577372511	0.460396817907323	0.283880009354148	NA	NA	0.0418877375754965	0.622988462530828	73.7600657226039
a3648	ARID1A_mut	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.52571026634388	2.94522176575736	0.58048850058652	0.988960408015167	0.913387716810304	0.623028141531488	0.586968392143781	0.635533508829831	0.283886922715387	NA	NA	0.662999451898315	0.290340309141301	73.7600657226039
a3649	gain_cnaOV19	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	3.10161053391189	2.1651872714946	0.936423262417296	2.21300979496649	0.978769628955077	0.785427638597046	0.42314465328947	0.956735103659694	0.28393147437466	NA	NA	0.377366196632244	0.541832639101932	73.7600657226039
a3650	TP53_mut	1114	Cetuximab	EGFR	22	10	4.18661983833127	NA	5.99808544280139	5.43584264544005	0.562242797361346	1.11752226730653	1.56643771394401	0.443065735386204	0.503115520656669	0.358930835459598	0.283948658766823	NA	NA	0.565653095558225	0.324561371807318	73.7600657226039
a3651	NF1_mut	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	2.00251361865064	0.678184561772273	1.32432905687837	2.68203212193078	1.95104493172497	0.648570343644667	0.493778223627313	0.678779373731541	0.284003065559815	NA	NA	0.409118411409659	0.403053120530328	73.7600657226039
a3652	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1023	GW 441756	NTRK1	8	23	0.693147180559945	NA	1.87500938730795	2.44575881084349	-0.57074942353554	1.39231276039684	1.18848143466133	0.460002915569114	0.409929033023346	0.480234193728217	0.284252552658893	NA	NA	0.842313094697126	0.323056046469273	73.7600657226039
a3653	NF1_mut	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.09010260220874	8.84728248164802	-0.757179879439287	0.747034544328578	1.26070978766749	0.621831073043629	1.01358081120576	0.600598081212797	0.284470898236525	NA	NA	0.524077844048899	0.140509814404187	73.7600657226039
a3654	loss_cnaOV85	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.63575553593593	2.28481818750139	0.350937348434539	0.662416668797611	0.908588680799184	0.40571852328628	0.529783390070097	0.386244464465327	0.284477966363314	NA	NA	0.602984059021221	0.276998451456386	73.7600657226039
a3655	loss_cnaOV82	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	2.57673039162112	1.65389426120096	0.922836130420162	1.47377191689121	1.70683435447514	0.545164401849743	0.626172964651683	0.540671171751718	0.284725395272566	NA	NA	0.223259781634703	0.394623398099008	73.7600657226039
a3656	gain_cnaOV18_(CCNE1)	134	Etoposide	TOP2	4	15	2.77258872223978	NA	3.03201801300681	2.08365553484379	0.948362478163014	1.03174846757837	1.93402279911654	0.524588477621401	0.919179924142681	0.490357444905109	0.284814545925819	NA	NA	0.397430163427997	0.217555423425928	73.7600657226039
a3657	loss_cnaOV56	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.925083344502899	0.229840896404467	-1.15492424090737	1.07023393091585	1.63077272089838	0.722532949352577	1.0791325219142	0.708206745248428	0.28506676594835	NA	NA	0.455558754779899	0.189921487837593	73.7600657226039
a3658	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.59819497341097	3.98880501680261	0.609389956608364	1.39102955149657	1.05554712491701	0.550899587458626	0.438085557530203	0.577321412017747	0.285068080617951	NA	NA	0.817190713922219	0.395402288444035	73.7600657226039
a3659	SMAD4_mut	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.47316368476983	3.01195213490066	0.461211549869171	1.20985986637048	0.875305845443486	0.505129896399264	0.381210719265185	0.526914737597225	0.285118569471245	NA	NA	0.232819693529901	0.508482772280689	73.7600657226039
a3660	TP53_mut	197	Bryostatin 1	PRKC	12	7	-4.8283137373023	NA	-2.46675040183893	-2.08523566188757	-0.38151473995136	0.85668418203254	0.458155867835189	0.514918498558439	0.445338840091795	0.832718222630296	0.285149219468486	NA	NA	0.666494415301095	0.223435478868948	73.7600657226039
a3661	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	221	TAK-715	p38a	7	25	2.99573227355399	2.32630161961136	4.59739931002934	4.18849171005575	0.408907599973594	0.950112050131837	0.869486777826252	0.461417438995687	0.43037829055726	0.470286162367963	0.285215849503046	NA	NA	0.515866200437936	0.332138619927959	73.7600657226039
a3662	loss_cnaOV83	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	0.289765933560781	1.13647623245423	-0.846710298893453	0.833858250572243	1.60999409091886	0.553608910949306	1.01541274948397	0.525908948156585	0.285325413418196	NA	NA	0.788199140246346	0.109482783569484	73.7600657226039
a3663	PIK3CA_mut	211	TL-2-105	CRAF	6	26	2.32630161961136	1.63315443905142	4.47628384336522	4.39365771913457	0.0826261242306554	0.397809400474327	0.67399682072191	0.129844824588396	0.207702794685436	0.122591267036179	0.285392071104777	NA	NA	0.264734878529167	0.699690579604075	73.7600657226039
a3664	loss_cnaOV44	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	6.18163966145846	5.47223953711431	0.709400124344153	1.17317710003621	0.948605219253192	0.734974575010925	0.604682894272533	0.747834936964233	0.285583169997215	NA	NA	0.297706442388687	0.406068803340687	73.7600657226039
a3665	gain_cnaOV72_(ASXL1)	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	0.277991370437127	0.847203845169207	-0.56921247473208	0.947743217623596	1.04754137985986	0.55007471098406	0.600597782339549	0.543379465170366	0.285653769564451	NA	NA	0.768887515284922	0.271028590710883	73.7600657226039
a3666	gain_cnaOV49	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.18293633157392	4.52040716668827	-0.337470835114354	0.180835951268997	0.720839679448359	0.482990907443352	1.86617114985261	0.468163510883047	0.285670121855772	NA	NA	0.0776892072480634	0.0687963573628945	73.7600657226039
a3667	gain_cnaOV48_(SOX17)	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.46225780092614	5.74122675580797	-0.278968954881837	0.1924557826943	0.488494140828442	0.587873466203624	1.44952233170856	0.571079428729138	0.285683657236447	NA	NA	0.37530219658244	0.105284339485824	73.7600657226039
a3668	loss_cnaOV70	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	0.252246869818591	1.25943658350601	-1.00718971368741	1.12685874414049	1.49597747536266	0.682861969787709	0.893802988994547	0.673265293278063	0.285700457015607	NA	NA	0.81064501213876	0.256129961154581	73.7600657226039
a3669	loss_cnaOV81_(RB1)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	2.31431732235027	2.86456263569521	-0.550245313344945	1.09380832507132	0.935701124253867	0.577897757367941	0.503054603565088	0.588056697894547	0.285719396827182	NA	NA	0.965745401363876	0.397000992524283	73.7600657226039
a3670	loss_cnaOV38	298	OSI-930	KIT, VEGFR, PDGFR	8	24	2.32630161961136	NA	4.88817894850641	4.30602851433573	0.582150434170678	1.0335245786627	0.93323534766959	0.60794168408771	0.563267140607276	0.623798097258514	0.285741665469829	NA	NA	0.0292186946777323	0.185226082620561	73.7600657226039
a3671	gain_cnaOV48_(SOX17)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	2.80015705017601	3.56348091478186	-0.763323864605848	0.884476752313558	1.11314081441781	0.694625709695704	0.863023095416803	0.685738816436338	0.285841377225473	NA	NA	0.72307663157326	0.269142095074394	73.7600657226039
a3672	gain_cnaOV49	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	3.43416268880149	4.15124904325244	-0.717086354450952	1.15438385203942	1.1053758931222	0.646775116034984	0.621185364975518	0.648726246802343	0.285846866179606	NA	NA	0.817202320974785	0.396270733149885	73.7600657226039
a3673	loss_cnaOV81_(RB1)	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	4.72690763718327	3.76023781620583	0.966669820977444	1.95330689261832	1.51814499756511	0.616196215009787	0.494888859825639	0.636744067613993	0.28599867366932	NA	NA	0.711744805232699	0.402855251763292	73.7600657226039
a3674	loss_cnaOV38	268	YM155	BIRC5 (Survivin)	8	22	1.63315443905142	NA	-4.92206709349943	-3.87082692146682	-1.05124017203262	0.780893902135771	2.63781287693086	0.453601748609045	1.34620102571865	0.398527196991984	0.286018339882289	NA	NA	0.926984482084408	0.104667848568077	73.7600657226039
a3675	RB1_mut	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.52338455735657	2.97001663184242	0.553367925514159	0.628526960307799	1.22207491428289	0.464750301315777	0.880420348624611	0.45281015021806	0.286207872954391	NA	NA	0.0843485031950543	0.269314321806687	73.7600657226039
a3676	gain_cnaOV96	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	6.03339756451673	5.44714361992988	0.586253944586852	0.70249357943184	0.997936360107423	0.608279149388473	0.834532815319111	0.587466263403555	0.286297793534269	NA	NA	0.297734527135909	0.153124391040726	73.7600657226039
a3677	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-0.832614273998038	-2.42359900533375	1.59098473133571	3.65945608671473	2.45417693081664	0.606122075305329	0.434759891534594	0.648276296365599	0.286312161149925	NA	NA	0.405373821104892	0.534798526800242	73.7600657226039
a3678	loss_cnaOV58	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.30424268932643	2.96206182766267	-0.657819138336241	0.344926344496954	1.176324282205	0.596760216486737	1.90712930117186	0.559215811734472	0.286458243973007	NA	NA	0.38440997989438	0.0247304948789745	73.7600657226039
a3679	loss_cnaOV1	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.24070777968931	4.76739186978571	0.473315909903592	0.724495779211163	0.74089973858101	0.639773913499231	0.653303888697519	0.638839353365273	0.286531080972819	NA	NA	0.762100187004811	0.376615095337621	73.7600657226039
a3680	loss_cnaOV58	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.53498790302456	5.74842258541062	-0.213434682386065	0.463093084448905	0.477058334078147	0.449128143783027	0.460889375275511	0.4473974504575	0.286663825923154	NA	NA	0.375340427076481	0.384355681990366	73.7600657226039
a3681	loss_cnaOV43_(NF1)	192	LFM-A13	BTK	3	16	2.77258872223978	NA	5.12945908203188	4.64926517225481	0.480193909777062	1.12983021825503	0.588358114171034	0.711403587857951	0.425014220737254	0.816159237395119	0.28708927077325	NA	NA	0.955823137551819	0.541055846192408	73.7600657226039
a3682	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.75183241001748	2.9156773971699	0.836155012847579	1.24102061419566	1.15836900597016	0.716382569632226	0.673763999794245	0.721838212640439	0.287271773405094	NA	NA	0.08437531343053	0.27656739144356	73.7600657226039
a3683	loss_cnaOV42	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	2.59995182623923	3.34415517709669	-0.744203350857459	0.941909257471741	1.07890553324823	0.698127972299211	0.790100898737357	0.689776192561465	0.287454097939085	NA	NA	0.0591041847678334	0.217141215492163	73.7600657226039
a3684	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.92366690586102	4.45062744754129	0.473039458319731	1.18909171361557	0.878060176736507	0.516897610132936	0.397815789062562	0.538732390845785	0.287531079860059	NA	NA	0.522674227468697	0.492383276466407	73.7600657226039
a3685	loss_cnaOV40	1019	Bosutinib	SRC, ABL, TEC	7	24	0.693147180559945	NA	2.50097848836371	1.49672964103792	1.0042488473258	1.00357159233738	1.66679872871051	0.646653263411489	1.00067484471819	0.602501567842398	0.287588565517564	NA	NA	0.0386485092360511	0.0655300286028701	73.7600657226039
a3686	loss_cnaOV85	178	BAY 61-3606	SYK	6	13	2.07944154167984	NA	3.18557428065985	2.48900206118236	0.696572219477491	1.42681242663053	1.25255788280181	0.533271421648141	0.488201677022445	0.556119784196599	0.287601972163029	NA	NA	0.93964773506606	0.332009983398598	73.7600657226039
a3687	gain_cnaOV19	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.46579473115921	3.92957467825275	0.536220052906463	0.251980330717339	0.774076991731212	0.714336943759309	2.12802345079852	0.692721859239369	0.287636859757732	NA	NA	0.520011026743571	0.0330148550554237	73.7600657226039
a3688	loss_cnaOV35	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.95910502894863	2.40461946467157	0.554485564277065	1.13099635015202	0.686852988802783	0.736534520974766	0.490262912168139	0.807284198098285	0.287866530134577	NA	NA	0.743194305618265	0.488358551877772	73.7600657226039
a3689	SMARCA4_mut	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	-0.146806526280694	0.438969235123799	-0.585775761404494	0.621558981540496	0.918663044564982	0.64990675868914	0.942429888073831	0.637639409650878	0.287942624864864	NA	NA	0.908389933448412	0.237092082264723	73.7600657226039
a3690	gain_cnaOV48_(SOX17)	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	3.21578250074737	3.86152622488073	-0.645743724133362	1.46423937179504	0.98209914463691	0.632246866745341	0.441009671350205	0.65751378326686	0.287965451088911	NA	NA	0.713534970698106	0.527161031741882	73.7600657226039
a3691	gain_cnaOV49	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	0.357091717619345	1.65249686252978	-1.29540514491044	1.262774143846	1.93221435472594	0.683606614637492	1.0258407263274	0.670425173967911	0.288009777702565	NA	NA	0.779733750456764	0.20700027093123	73.7600657226039
a3692	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	3.96413808495895	4.47949801479994	-0.515359929840989	0.883610519889201	0.715117894968188	0.708334547075329	0.5832433161905	0.720664289716753	0.28807428961014	NA	NA	0.518793772149473	0.420329607242093	73.7600657226039
a3693	loss_cnaOV54	153	Midostaurin	KIT	6	13	-0.669430653942629	NA	-0.346478531497763	0.333411317556711	-0.679889849054474	0.871649879790593	1.44963414675632	0.520407105468384	0.780003376146638	0.469007887663095	0.288191833590961	NA	NA	0.866646558272272	0.224188836936545	73.7600657226039
a3694	loss_cnaOV35	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.4185607776398	2.94621298637973	-0.527652208739926	0.902171781184216	0.765843108057021	0.671835740236859	0.584868890542459	0.688982120735674	0.288291772915891	NA	NA	0.0180397398119842	0.272701007581736	73.7600657226039
a3695	gain_cnaOV19	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.88574428969655	4.16368248060172	0.722061809094831	0.740848120233949	0.976218732782019	0.749982514415421	0.974642155893996	0.739651662939417	0.28841193512693	NA	NA	0.203851431611995	0.225130548136952	73.7600657226039
a3696	gain_cnaOV18_(CCNE1)	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.94574416532328	4.34144422885708	0.604299936466204	0.318358219003687	0.77887643649114	0.799153666408002	1.89817601806349	0.7758611098682	0.288414846599385	NA	NA	0.0404436998455976	0.0482159317071692	73.7600657226039
a3697	gain_cnaOV19	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.94574416532328	4.34144422885708	0.604299936466204	0.318358219003687	0.77887643649114	0.799153666408002	1.89817601806349	0.7758611098682	0.288414846599385	NA	NA	0.0404436998455976	0.0482159317071692	73.7600657226039
a3698	loss_cnaOV52, loss_cnaOV53	295	NVP-BHG712	EPHB4	8	24	2.32630161961136	NA	2.78360097498676	3.40697268599043	-0.623371711003661	1.10119232697572	1.04692285870272	0.588178452613342	0.566087953696218	0.595432324188722	0.288464410444306	NA	NA	0.0591239838845565	0.186783624501232	73.7600657226039
a3699	gain_cnaOV94	266	Zibotentan, ZD4054	Endothelin A Receptor	7	25	2.99573227355399	NA	5.91143394763723	5.66009246750996	0.251341480127266	0.501466134673564	0.461560747472301	0.534981887543026	0.501213267952541	0.54454691284672	0.28851306328451	NA	NA	0.375412103001194	0.263482410760214	73.7600657226039
a3700	gain_cnaOV72_(ASXL1)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-0.946723530711561	-0.468753034024048	-0.477970496687513	1.42772326762236	1.96136915471524	0.254477026308155	0.334778109684725	0.243692267484907	0.288561496377667	NA	NA	0.0383007803784945	0.603418229371492	73.7600657226039
a3701	loss_cnaOV59	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	5.01023892083107	4.36366336408882	0.646575556742246	1.14431791767521	0.976844724989785	0.650291707376266	0.565031401462127	0.661902081468482	0.288647968844312	NA	NA	0.368820032839139	0.347712204207711	73.7600657226039
a3702	BRCA1_mut	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.83998655313287	4.33646573863635	0.503520814496522	1.00552511372809	0.832550660566733	0.591800651334372	0.500754091192873	0.604793003411667	0.288713332909423	NA	NA	0.867837122690464	0.39834412599808	73.7600657226039
a3703	loss_cnaOV54	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	22	0	NA	-2.66323881622032	-1.65308474895001	-1.01015406727031	2.3120633769764	1.81672123102887	0.507608354417327	0.436905872619867	0.556031409782243	0.288829473478908	NA	NA	0.272227264065077	0.222986078339311	73.7600657226039
a3704	loss_cnaOV84	1003	Camptothecin	TOP1	6	25	-2.30258509299405	NA	-2.87342190873152	-3.88742694527626	1.01400503654474	1.98741880425368	1.62581395869627	0.598700505985841	0.510212057153965	0.623690694203331	0.288867198819818	NA	NA	0.238808332420879	0.285689714338093	73.7600657226039
a3705	gain_cnaOV49	1061	SB590885	BRAF	3	30	1.6094379124341	NA	3.11713068709286	4.00858073797255	-0.891450050879684	1.56540999392782	1.24339837934067	0.703787778728829	0.569467458581197	0.716946447487238	0.289006062432969	NA	NA	0.56818986081387	0.429587383145629	73.7600657226039
a3706	loss_cnaOV21, loss_cnaOV22	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	2.96437080925334	3.53353114537643	-0.569160336123092	0.794798842921019	0.903330078829462	0.634710335858149	0.716106145841044	0.630069062751251	0.289049522951752	NA	NA	0.791603051044826	0.340703995180873	73.7600657226039
a3707	loss_cnaOV16, loss_cnaOV17	261	TL-1-85	MAP3K7 (TAK1)	6	26	2.32630161961136	NA	3.90909148325174	3.47402341409044	0.4350680691613	1.19371964384304	0.895564389538208	0.457116912280765	0.364464195094126	0.485803225590111	0.289107973392593	NA	NA	0.724971089453083	0.431406192052909	73.7600657226039
a3708	loss_cnaOV38	310	YM201636	FYV1	8	24	1.63315443905142	NA	2.04949775569386	2.45938951020284	-0.409891754508974	1.19247632376837	0.722230106870749	0.479182482535665	0.343731566270152	0.567536233410343	0.289149338159383	NA	NA	0.646196489512613	0.383286773213641	73.7600657226039
a3709	gain_cnaOV51_(MYC)	235	QL-XII-47	BTK, BMX	8	24	2.32630161961136	NA	1.25750273989039	1.66788422343446	-0.410381483544068	1.3831405150143	1.69091976831893	0.252646735150581	0.296702669822254	0.242697194292109	0.289289105400886	NA	NA	0.0750874234825952	0.503688641856989	73.7600657226039
a3710	loss_cnaOV87, loss_cnaOV88	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.91886754172153	4.30951353857299	0.609354003148545	1.0160762957318	1.05812650975549	0.577381344716764	0.599712842144079	0.57588010273871	0.289325489949539	NA	NA	0.345481441324687	0.411015063793987	73.7600657226039
a3711	loss_cnaOV39	1373	Dabrafenib	BRAF	10	22	2.30258509299405	NA	4.2479188803893	3.37282990489036	0.875088975498947	1.20136555624603	2.25808364555119	0.43742186359514	0.728411906725029	0.38753612038377	0.289325850806914	NA	NA	0.744135767122342	0.164268840984712	73.7600657226039
a3712	loss_cnaOV82	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-0.00629090394425115	-1.16836242373327	1.16207151978902	2.72776326461398	1.89168828275402	0.593328944117232	0.42601626573099	0.614303915916432	0.289353689552362	NA	NA	0.437549541216676	0.540117175347608	73.7600657226039
a3713	loss_cnaOV57_(ZNRF3)	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.26245499335363	4.52312411968085	-0.260669126327218	0.680464917666947	0.675765288374177	0.385460969961031	0.38307504113651	0.385739147617898	0.289561740267557	NA	NA	0.0503895947073482	0.514412941658143	73.7600657226039
a3714	loss_cnaOV54	1230	IOX2	EGLN1	10	22	-2.30258509299405	NA	0.152419427019082	-0.161452700913212	0.313872127932294	0.739354161950857	1.04124014698869	0.326716222166714	0.424522027581629	0.301440670377556	0.289625022024455	NA	NA	0.543627924016683	0.339946014677623	73.7600657226039
a3715	NF1_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	0.669691152116433	1.29142050634701	-0.62172935423058	0.616263661611476	1.27957603119766	0.505017580557811	1.00886908146557	0.485886996217531	0.289670541631763	NA	NA	0.2609298847023	0.152071527638167	73.7600657226039
a3716	loss_cnaOV82	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	5.0101092719544	4.32278547021886	0.687323801735535	0.621454113415202	0.992080843884301	0.70728330505774	1.10599284307307	0.692810274457524	0.28973627705082	NA	NA	0.505878708432702	0.181770587022832	73.7600657226039
a3717	loss_cnaOV56	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.13098388947661	2.55011280316675	-0.419128913690144	0.731742550245873	0.613338870603681	0.673912052462824	0.572781934779264	0.683356189829636	0.289772409097658	NA	NA	0.856224873281382	0.427660552395929	73.7600657226039
a3718	loss_cnaOV38	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	4.34666680078843	3.41283801271556	0.933828788072869	1.18388894507622	2.18978521378151	0.466720327854724	0.788780731466962	0.426447663540597	0.289814811946663	NA	NA	0.744145597471792	0.140922202641441	73.7600657226039
a3719	loss_cnaOV40	228	KIN001-102	AKT1	7	25	2.32630161961136	NA	3.34200154884304	2.63398065676989	0.708020892073151	0.721616927323481	1.29389094507796	0.589307962425133	0.981158929709758	0.547202911316836	0.289824669730609	NA	NA	0.0906458626235878	0.0759272136692134	73.7600657226039
a3720	loss_cnaOV55	229	LY317615	PRKCB (PKCbeta)	7	25	2.99573227355399	2.32630161961136	2.2764497663337	2.88133808321972	-0.604888316886023	2.0465482932399	1.56710685083375	0.361339528877725	0.295565132219979	0.385990474462034	0.289893310506681	NA	NA	0.314981309990343	0.489060505502142	73.7600657226039
a3721	loss_cnaOV52, loss_cnaOV53	266	Zibotentan, ZD4054	Endothelin A Receptor	8	24	2.99573227355399	NA	5.89636069425741	5.65464432363127	0.241716370626141	0.382757884972872	0.49304370939054	0.514692482373753	0.631512452430007	0.490253431942029	0.28995957900193	NA	NA	0.375467761995925	0.171711417458853	73.7600657226039
a3722	loss_cnaOV83	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	3.14593798748409	2.20068908866396	0.945248898820128	2.11441664055084	1.41843354742256	0.619356985693937	0.447049498519779	0.666403371901166	0.29003790992167	NA	NA	0.236263910449453	0.383346379612147	73.7600657226039
a3723	gain_cnaOV18_(CCNE1)	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.85213081502436	1.60257029851368	1.24956051651068	1.67558019129745	1.55826853208002	0.797604867259025	0.74574796419807	0.801890361504465	0.290115168462035	NA	NA	0.0386871303113788	0.32431516266004	73.7600657226039
a3724	gain_cnaOV19	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.85213081502436	1.60257029851368	1.24956051651068	1.67558019129745	1.55826853208002	0.797604867259025	0.74574796419807	0.801890361504465	0.290115168462035	NA	NA	0.0386871303113788	0.32431516266004	73.7600657226039
a3725	loss_cnaOV34	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.33626955572375	1.38193838472603	0.954331170997721	2.06408027272302	1.87497896707987	0.50194155336884	0.462351771687023	0.508982334070667	0.290146004638001	NA	NA	0.779771173189438	0.37747191516483	73.7600657226039
a3726	loss_cnaOV83	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-3.845048149614	-4.86984347703021	1.02479532741621	3.24398624011788	1.67345407840843	0.502246233098406	0.315906188115944	0.61238329789776	0.290150475271547	NA	NA	0.338269723805213	0.579546792063345	73.7600657226039
a3727	SMAD4_mut	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.19368530889003	2.11261557175088	1.08106973713915	3.44700903075587	1.45335563741758	0.598601291506323	0.313625443824871	0.74384390806098	0.290225337288872	NA	NA	0.397807707663931	0.643527268680889	73.7600657226039
a3728	ARID1A_mut	1061	SB590885	BRAF	9	24	1.6094379124341	NA	3.78848932380107	3.97968376192689	-0.191194438125817	0.956570276498405	1.38852433976446	0.14810209611451	0.199874952027256	0.137696137295116	0.290228719892786	NA	NA	0.568226933559279	0.65861152082849	73.7600657226039
a3729	gain_cnaOV19	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	5.09772191735532	4.37646758299447	0.721254334360842	0.786308664286839	1.00791592100396	0.724799284625893	0.917266166734917	0.715589782173915	0.290269531193372	NA	NA	0.368880429079061	0.246698799133292	73.7600657226039
a3730	loss_cnaOV35	172	Embelin	XIAP	3	16	3.46573590279973	NA	2.51497722857549	3.20729527291225	-0.692318044336758	1.25589270008811	0.880674870875668	0.742284099995156	0.551255727729118	0.786122174291605	0.290336803531162	NA	NA	0.663306533445902	0.443711161000763	73.7600657226039
a3731	loss_cnaOV85	230	GSK429286A	ROCK2	7	25	2.99573227355399	2.32630161961136	5.94854575779057	5.42400181024625	0.524543947544317	0.921927368933633	0.972803959596257	0.544786169152174	0.568964503300344	0.5392082776493	0.290403482238705	NA	NA	0.297894176351187	0.217854715228478	73.7600657226039
a3732	PIK3CA_mut	1529	MLN4924	NEDD8-activating enzyme	5	12	0	NA	0.730215993337289	1.58665709125048	-0.856441097913195	1.19603847138194	1.50726267306247	0.598531616281064	0.716064841061203	0.568209584977694	0.290477685475396	NA	NA	0.85249085666733	0.243900837003938	73.7600657226039
a3733	loss_cnaOV57_(ZNRF3)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	1.7515021812315	0.897417114969365	0.854085066262136	1.49296278231083	1.539118971974	0.556564633147367	0.572073916631847	0.554918158904071	0.290517898303422	NA	NA	0.788287233741105	0.346882747878086	73.7600657226039
a3734	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.22778380699507	-3.47628496804481	1.24850116104974	2.33376130729061	1.71226357564825	0.698809929193152	0.534973802654735	0.729152438214466	0.29060007611755	NA	NA	0.134279236220472	0.369072824242686	73.7600657226039
a3735	SMAD4_mut	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.83820830381723	4.33671101440402	0.501497289413208	0.902549123041523	0.845250239003842	0.589328492991841	0.555645423180069	0.593312212492528	0.290724582141526	NA	NA	0.867857855226034	0.356558775723031	73.7600657226039
a3736	loss_cnaOV43_(NF1)	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	4.99572650530253	4.51301324625305	0.482713259049481	0.964769006804419	0.930208160512264	0.516331557494143	0.500340760995588	0.518930363698004	0.290740176297128	NA	NA	0.942385083135739	0.344928898839292	73.7600657226039
a3737	gain_cnaOV4_(KRAS)	207	AS601245	JNK 	6	12	2.07944154167984	NA	2.37875841290664	1.80082662221681	0.577931790689829	0.578526544013967	1.09061161170249	0.601774906229075	0.998971951537415	0.529915310352925	0.290856411295745	NA	NA	0.468061088880603	0.161578193661388	73.7600657226039
a3738	loss_cnaOV35	293	MP470	PDGFR	5	27	2.99573227355399	NA	4.7610375223571	3.9174288766505	0.843608645706601	1.16764532457066	1.82657422615257	0.481213562326143	0.722487066881198	0.461852923154153	0.290908866862352	NA	NA	0.617603730008326	0.216189535933125	73.7600657226039
a3739	loss_cnaOV70	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.02472582163421	1.66055338631934	-0.635827564685124	0.847209789456284	1.28737332493987	0.507793835251899	0.750496007716318	0.49389524574375	0.291028927029526	NA	NA	0.156209836881226	0.332065685352636	73.7600657226039
a3740	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.73825303372469	4.13844436137564	0.599808672349054	1.10683237425569	0.937493029699511	0.624136629395963	0.541914644258943	0.639800674082139	0.291113352352619	NA	NA	0.203945067285508	0.304849918548149	73.7600657226039
a3741	loss_cnaOV55	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	NA	0.721458175630751	1.37433175549932	-0.652873579868573	1.547696234461	1.09909220918929	0.537364126914585	0.421835735806351	0.594011652898661	0.291186926335399	NA	NA	0.26098546159976	0.295844878549268	73.7600657226039
a3742	gain_cnaOV18_(CCNE1)	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	3.88689382433469	3.13581451868419	0.751079305650507	1.29845004769644	1.20463760597606	0.61850568873091	0.578442972822087	0.623489837876964	0.291272351164427	NA	NA	0.596124374901538	0.339655934855216	73.7600657226039
a3743	gain_cnaOV4_(KRAS)	235	QL-XII-47	BTK, BMX	8	24	2.32630161961136	NA	2.07392399257714	1.39574380587221	0.678180186704926	1.93691600907662	1.49117357096739	0.422204886268744	0.350134018990444	0.454796275838608	0.291289511515315	NA	NA	0.0751322930472771	0.38693446508325	73.7600657226039
a3744	gain_cnaOV95_(MECOM)	265	Tubastatin A	HDAC6	8	23	2.99573227355399	NA	5.15384895803437	4.61799583180029	0.535853126234088	0.948144841577744	1.28771955263286	0.44122104879724	0.565159565011619	0.416125642527125	0.291566691849019	NA	NA	0.418608078392904	0.229401595460013	73.7600657226039
a3745	loss_cnaOV40	1020	Lenalidomide	TNFA	7	24	1.6094379124341	NA	4.772487856695	4.29126066279596	0.481227193899048	0.927068828594642	0.696574769913867	0.641553336666078	0.51908464512667	0.690847866853622	0.291614795936264	NA	NA	0.0404938905043523	0.238555182057677	73.7600657226039
a3746	gain_cnaOV72_(ASXL1)	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.95840661354227	3.46769972069227	0.490706892849996	0.631598493171686	0.926509713810128	0.549605775326206	0.776928536332984	0.529629517678816	0.291803301032924	NA	NA	0.659110839598585	0.181770953993057	73.7600657226039
a3747	gain_cnaOV95_(MECOM)	294	MPS-1-IN-1	MPS1	9	22	2.99573227355399	NA	4.03185703834169	4.38693698449165	-0.355079946149959	0.792936472847279	0.815076979984737	0.438896017090463	0.447803775345252	0.435639767616316	0.29183664654987	NA	NA	0.310395917300018	0.278921017063033	73.7600657226039
a3748	gain_cnaOV72_(ASXL1)	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-2.23328359567041	-1.14779080678167	-1.08549278888874	2.20080247303053	1.78144000424853	0.589020754597428	0.493225903819529	0.609334463299332	0.291866744148258	NA	NA	0.0705819874134362	0.345193206497532	73.7600657226039
a3749	loss_cnaOV83	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-1.09773551507171	-2.45896565646981	1.36123014139811	3.09391904497285	2.52068978532154	0.517393267459063	0.439969540770596	0.540022873629595	0.291967414060432	NA	NA	0.405763953214038	0.461493889523935	73.7600657226039
a3750	gain_cnaOV94	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	3.52714308714263	3.99278146520755	-0.465638378064923	2.1203941598215	1.32311746755765	0.308811685820597	0.219599915378054	0.351925198995708	0.292034704070606	NA	NA	0.0648120091386384	0.660891686977875	73.7600657226039
a3751	SMARCA4_mut	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	0.115707400420502	0.824735809327335	-0.709028408906833	0.726521458173382	1.05336589708267	0.685188616639723	0.975922184995706	0.67310742722022	0.292079813458602	NA	NA	0.769005389311279	0.224416883047388	73.7600657226039
a3752	SMAD4_mut	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	3.14105360848935	2.22840949593594	0.91264411255341	0.52354054624321	1.47357340111139	0.638207936177692	1.74321572436425	0.619340788769045	0.292105214826735	NA	NA	0.818620628786868	0.0642763945594416	73.7600657226039
a3753	loss_cnaOV36	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.71379522337074	4.28816466763105	0.425630555739684	0.605513121068578	0.575813107203018	0.736499228846819	0.702925404801392	0.739181776891399	0.292119968299513	NA	NA	0.247732159008197	0.347363903741935	73.7600657226039
a3754	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	281	CH5424802	ALK	5	27	1.63315443905142	NA	4.24948563553789	3.86799825172795	0.381487383809936	0.594325548217252	0.739228067879525	0.528675433399627	0.641882861933584	0.516061822306385	0.292137771189352	NA	NA	0.955205336081294	0.248948177055767	73.7600657226039
a3755	loss_cnaOV87, loss_cnaOV88	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.13285971952809	2.54991875178211	-0.41705903225402	0.175186983065772	0.64218897325747	0.670447991310129	2.38065080495987	0.6494334995173	0.292259112766032	NA	NA	0.856253520532648	0.0235331078155867	73.7600657226039
a3756	loss_cnaOV59	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.59652401151634	2.99493691741838	0.601587094097958	0.998880882879542	0.892949645200113	0.66566104385472	0.602261094800135	0.673707747499178	0.292405148108963	NA	NA	0.233082638892468	0.321621936948076	73.7600657226039
a3757	gain_cnaOV50	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.34964943616443	1.65230634382014	-0.302656907655718	0.392030946170563	0.706423370246217	0.444076722179443	0.772023001276126	0.428435581838451	0.292447279511136	NA	NA	0.203281320205591	0.247068161425749	73.7600657226039
a3758	loss_cnaOV34	1030	KU-55933	ATM	5	28	2.30258509299405	NA	3.75284203699973	4.22209344258266	-0.469251405582936	1.46319105345655	0.941185977530067	0.458427569236362	0.320704124368725	0.498574582267345	0.292458848325415	NA	NA	0.524493440056288	0.522229500765859	73.7600657226039
a3759	loss_cnaOV82	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.75743337543105	4.8822402397338	0.875193135697249	0.60151459637288	1.25187881619263	0.717747211628729	1.4549823744505	0.699103718648259	0.292499998775103	NA	NA	0.366411707258648	0.102072000510936	73.7600657226039
a3760	loss_cnaOV38	1067	CCT007093	PPM1D	8	25	1.88706964903238	NA	4.79381321971384	4.39242072950637	0.401392490207473	0.76904279856473	0.656005605075433	0.587546730109363	0.52193777895924	0.611873568003002	0.292678377581471	NA	NA	0.0778452434915153	0.211892390414671	73.7600657226039
a3761	loss_cnaOV57_(ZNRF3)	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	1.74932677744475	0.717136383496256	1.0321903939485	2.92467419731082	1.9335945638337	0.500410827040279	0.352924915499161	0.53381945380628	0.292699036482581	NA	NA	0.409473161310458	0.537950988279551	73.7600657226039
a3762	loss_cnaOV84	310	YM201636	FYV1	6	26	1.63315443905142	NA	1.99276880266495	2.44095067209343	-0.448181869428483	1.10861199829957	0.795862101828339	0.523601545140042	0.404272973877175	0.563140107311143	0.292737648871655	NA	NA	0.646292043674883	0.383980532609449	73.7600657226039
a3763	gain_cnaOV26	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.95774049009752	3.23465160971251	0.723088880385011	1.41220497220377	1.0684052577876	0.660542382272185	0.51202827820144	0.676792701191257	0.292904312289895	NA	NA	0.950281742937116	0.471033887851438	73.7600657226039
a3764	SMAD4_mut	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.84005041532853	4.21979091984874	0.620259495479792	1.60331418352813	0.808165051889336	0.701872387818293	0.386860854754553	0.767491113392918	0.292909645674814	NA	NA	0.51612828786582	0.573326643380573	73.7600657226039
a3765	loss_cnaOV39	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	23	1.38629436111989	NA	1.44442841989994	1.11676848232738	0.327659937572556	1.35198656059702	1.18980226538953	0.2644387484765	0.242354433928593	0.275390245172615	0.292985613759397	NA	NA	0.261050910826648	0.517231620777403	73.7600657226039
a3766	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	155	AP-24534	ABL	3	16	-0.669430653942629	NA	1.44774189271787	0.664952518480676	0.782789374237191	1.95473665447411	1.1094027284596	0.631711992168081	0.400457715081721	0.705595320938225	0.293100662428168	NA	NA	0.575158455358839	0.563216893147788	73.7600657226039
a3767	loss_cnaOV42	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.51547166664035	5.75068590331414	0.764785763326207	0.601446002650306	1.31161242749971	0.599071556544136	1.27157842924574	0.583088225829101	0.29318831548291	NA	NA	0.565945596272671	0.139519653532493	73.7600657226039
a3768	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	3.73101457167754	2.728611088928	1.00240348274955	2.46305227548644	1.46006906380711	0.64899024755073	0.406976129871859	0.686545251589537	0.293215114327051	NA	NA	0.968416552745228	0.555851219316727	73.7600657226039
a3769	SMAD4_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	4.83887582397164	3.91752048130474	0.921355342666902	1.24752065997264	1.50010794714709	0.623888624572909	0.738549165740558	0.614192694878486	0.293261939746856	NA	NA	0.323540326409692	0.244601762946514	73.7600657226039
a3770	ARID1A_mut	186	Bexarotene	Retinioic acid X family agonist	5	13	2.07944154167984	NA	3.39006476608567	3.92955306854687	-0.539488302461198	1.13223443638914	0.895586879362105	0.56183117393386	0.476481093599047	0.60238522346984	0.293269309237717	NA	NA	0.803027107791624	0.375496881429654	73.7600657226039
a3771	loss_cnaOV34	293	MP470	PDGFR	5	27	2.99573227355399	NA	4.75720006914053	3.91813951613505	0.839060553005483	1.1706733309576	1.82661596044873	0.47853544871425	0.716733294265052	0.459352469907991	0.293362971828357	NA	NA	0.617673040304868	0.219297974028106	73.7600657226039
a3772	loss_cnaOV39	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	23	0	NA	-1.61097410485811	-2.15451088724968	0.543536782391562	1.93195755703745	2.0736240765755	0.267289677742197	0.281339918887787	0.262119247423665	0.293363991954877	NA	NA	0.272394063527998	0.476858105567748	73.7600657226039
a3773	loss_cnaOV87, loss_cnaOV88	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.51511329647579	3.32726939221507	-0.812156095739273	1.13472645037115	1.06335937317971	0.760256772089927	0.715728531289306	0.763764458398222	0.293389982912128	NA	NA	0.0592193188523632	0.340219052476479	73.7600657226039
a3774	gain_cnaOV96	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.00494867768925	4.45801344680607	-0.453064769116819	0.784496775000893	1.00551088109371	0.462816487073598	0.57752279366133	0.450581667126283	0.293592958729185	NA	NA	0.506010305502385	0.296947933409099	73.7600657226039
a3775	loss_cnaOV55	224	AS605240	PI3Kgamma	7	25	2.99573227355399	2.32630161961136	2.73468322059854	3.55441806979705	-0.81973484919851	1.89899343469046	1.57611923488804	0.498086113486183	0.431668079638269	0.520096976836107	0.293648184319381	NA	NA	0.625309966078206	0.324665518021101	73.7600657226039
a3776	ARID1A_mut	1013	Nilotinib	ABL	7	14	0.693147180559945	NA	2.88902773467721	3.42946616548124	-0.54043843080403	0.85161140866854	1.07215057664025	0.536290582494407	0.634606846858691	0.504069523981954	0.293731544515521	NA	NA	0.557280994828836	0.229074173694011	73.7600657226039
a3777	loss_cnaOV52, loss_cnaOV53	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	9	24	1.6094379124341	NA	2.92763290958256	2.12501200974035	0.802620899842215	1.63979650005133	1.47837049164497	0.527460856663972	0.489463722978486	0.542909172212403	0.293733377359294	NA	NA	0.236395880410054	0.220726485947691	73.7600657226039
a3778	loss_cnaOV40	224	AS605240	PI3Kgamma	7	25	2.99573227355399	2.32630161961136	3.90511903041064	3.22669604304966	0.678422987360989	1.26541344754802	1.74172865156898	0.409316669586152	0.536127531025978	0.389511297727033	0.293756198894961	NA	NA	0.625312946456494	0.272019337005535	73.7600657226039
a3779	NF1_mut	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.84875074552166	3.22439697035246	0.624353775169202	1.30880067644525	1.0692441007754	0.569894913766446	0.477042674569033	0.583920710637011	0.293869902813281	NA	NA	0.950285589030437	0.41890539088491	73.7600657226039
a3780	loss_cnaOV42	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-1.80676008161279	-2.86438623521878	1.05762615360599	1.83987745978864	1.73561336915322	0.605631382638692	0.574835105446362	0.609367369716673	0.293877014253972	NA	NA	0.692511643036813	0.342662681079429	73.7600657226039
a3781	loss_cnaOV44	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.32636002210851	3.08290811728012	-0.756548095171616	1.60830549985253	1.01712763787421	0.709187783776628	0.470400738691118	0.743808414008687	0.293968966312695	NA	NA	0.428620505825807	0.502676610317334	73.7600657226039
a3782	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.26759869513069	2.29026514100238	0.977333554128301	1.93733737143162	1.22771009134221	0.760352036414424	0.504472565563575	0.796062165669596	0.294005018011133	NA	NA	0.105808760881578	0.475906300930847	73.7600657226039
a3783	loss_cnaOV58	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.70459952763221	4.19892926975696	0.505670257875247	1.13393020641348	0.837875538928352	0.572606395387384	0.445944781270653	0.603514763686743	0.294267363204017	NA	NA	0.516173617803601	0.386952424036569	73.790827954627
a3784	gain_cnaOV72_(ASXL1)	341	EX-527	SIRT1	4	27	2.99573227355399	NA	5.98260012324102	5.74230778343038	0.240292339810648	0.268846738976046	0.587805519401158	0.426618301806275	0.893789304366671	0.408795650737428	0.294283175972658	NA	NA	0.106138432763312	0.207390028846493	73.790827954627
a3785	SMAD4_mut	172	Embelin	XIAP	3	16	3.46573590279973	NA	2.51951034753279	3.20644531310775	-0.686934965574963	1.25514328023746	0.881526857870111	0.736045875558171	0.547296054873515	0.779255855272172	0.294481523456358	NA	NA	0.66349919584764	0.446578958779829	73.8075493936621
a3786	PTEN_mut	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.51651772989587	3.56740443644023	-0.0508867065443575	0.873493824681655	0.929736845084018	0.0550457704861716	0.0582565155087423	0.0547323759550036	0.294505438321947	NA	NA	0.13812401888897	0.918932035938669	73.8075493936621
a3787	NF1_mut	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	4.55992190215831	3.80520149910432	0.754720403053993	1.42313539900264	1.73965085804249	0.44145313466209	0.530322275436981	0.433834409683349	0.29464887020188	NA	NA	0.142104831159252	0.386386623383917	73.8239964011846
a3788	loss_cnaOV57_(ZNRF3)	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	2.25268910755512	1.311783016438	0.940906091117121	2.52011414231574	1.66863375842766	0.529862962609447	0.373358521869378	0.563878134650548	0.294754546309883	NA	NA	0.609901915104433	0.515924500082424	73.8309775492077
a3789	gain_cnaOV48_(SOX17)	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	1.12442031433098	2.13681494396081	-1.01239462962983	2.09253302824382	1.97261137010337	0.511095647174606	0.483812974975831	0.513225587651751	0.29486929374196	NA	NA	0.12768097055642	0.494744980619046	73.8364211820466
a3790	loss_cnaOV56	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.92681522310923	-2.04325191220652	-0.883563310902712	2.00019911833116	1.21152210199986	0.691804350591011	0.441737676416888	0.729300199677921	0.294968205182856	NA	NA	0.603070667405986	0.525999253052959	73.8364211820466
a3791	loss_cnaOV40	1007	Docetaxel	Microtubules	7	24	-4.38202663467388	NA	-4.00639783305889	-4.83587665493226	0.829478821873375	1.82354340979051	1.24894245005903	0.597827667347093	0.454871991212244	0.664144950661392	0.295009734203749	NA	NA	0.130463099908955	0.292875288805945	73.8364211820466
a3792	loss_cnaOV83	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.21300219191487	4.66844941677335	0.544552775141518	0.922114162875492	1.26227270673208	0.445988659386617	0.590548108971021	0.431406598777944	0.295178531689414	NA	NA	0.4187461696503	0.293605045177804	73.8521574339362
a3793	loss_cnaOV55	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	8	25	1.6094379124341	NA	2.96567599221964	2.14494305929017	0.820732932929473	1.74876514027203	1.45067042237842	0.538860313484963	0.469321416597889	0.565761126902866	0.295228277677154	NA	NA	0.236448668476567	0.256436794356211	73.8521574339362
a3794	loss_cnaOV20	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.90898985101611	3.47685097301193	0.432138878004171	0.915809851458147	0.894164471106673	0.481716838711969	0.471865286572449	0.483287909515494	0.295331376019898	NA	NA	0.65920084246418	0.37141971311928	73.8584754541083
a3795	gain_cnaOV72_(ASXL1)	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.496710371460731	-0.862653554001146	0.365943182540415	0.403430805869463	0.837435830901152	0.455445176299956	0.907077935587354	0.43698056500237	0.295559636482924	NA	NA	0.0750405308168187	0.195599221197221	73.8960832893021
a3796	PIK3R1_mut	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	5.40035392883234	4.63242023659692	0.767933692235418	0.545462479832092	1.27773060395662	0.638075695393362	1.40785795655791	0.601013773840459	0.295658159158658	NA	NA	0.418764343572469	0.0450162225154432	73.9012426981161
a3797	TP53_mut	1016	Temsirolimus	MTOR	21	10	-1.6094379124341	NA	-1.88452232273365	-2.33351276412174	0.448990441388082	1.49796390332838	1.68627804641039	0.288028074736193	0.299733818946139	0.266261214954353	0.295882397376303	NA	NA	0.0355325075817368	0.483188621004367	73.9378143449798
a3798	loss_cnaOV54	1175	AG-014699	PARP1, PARP2	11	22	1.6094379124341	NA	4.2474515811568	3.72801110809939	0.519440473057412	0.770853049778823	1.16430558630078	0.493031782494385	0.673851485969281	0.446137576912064	0.29605456650016	NA	NA	0.310528021658307	0.137736011737658	73.9454346951168
a3799	loss_cnaOV84	1026	17-AAG	HSP90	6	27	0	NA	-1.05376027343569	-0.414625910479907	-0.639134362955781	2.01839689477837	2.35212707391153	0.277694341745384	0.316654452159154	0.271726119751224	0.296123208337205	NA	NA	0.0583060694748808	0.515071112984932	73.9454346951168
a3800	loss_cnaOV81_(RB1)	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.4908848005984	4.84880673704999	0.64207806354841	0.383246734783142	0.86942159539978	0.759926039743452	1.67536473314437	0.738511749588147	0.296146692312952	NA	NA	0.148999061313803	0.0704561345541855	73.9454346951168
a3801	loss_cnaOV83	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	1.42352638161296	2.36501134190209	-0.941484960289125	0.848072854221123	1.32139931832471	0.740217501238186	1.11014632245692	0.712490877839074	0.296229776482912	NA	NA	0.678351331853542	0.185313559858354	73.9467204773285
a3802	gain_cnaOV50	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	4.76187384739038	4.38394147480405	0.377932372586323	0.67451659149016	0.738813156652606	0.515851823673104	0.560301076881422	0.511539851697618	0.296392204316099	NA	NA	0.519072101954356	0.357610570707569	73.9678066327701
a3803	loss_cnaOV52, loss_cnaOV53	1020	Lenalidomide	TNFA	8	23	1.6094379124341	NA	4.74772473986461	4.27895099935005	0.468773740514564	0.610296077781804	0.787983170902144	0.625897216079907	0.768108722275228	0.594903238831707	0.296680430701445	NA	NA	0.0405720064304429	0.103414195769586	73.9866154159401
a3804	loss_cnaOV1	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	4.10925948052803	3.42321994010129	0.686039540426747	0.237465896134755	1.14196977647719	0.621608921615652	2.88900238557809	0.600751048371068	0.296755035011969	NA	NA	0.723319162676172	0.0159322361457099	73.9866154159401
a3805	loss_cnaOV1	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	4.02724294857381	2.72176384151653	1.30547910705728	1.41529658658808	1.85236255526991	0.714750775960525	0.92240673751956	0.70476435800499	0.29676938378089	NA	NA	0.340269264324257	0.244636123259262	73.9866154159401
a3806	loss_cnaOV87, loss_cnaOV88	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	2.40932259657485	1.45286387007824	0.956458726496613	0.958725942437131	1.25141298768308	0.779795425542385	0.997635178271327	0.764303020593898	0.296972182395669	NA	NA	0.156483341664234	0.216969390512089	73.9866154159401
a3807	loss_cnaOV52, loss_cnaOV53	1259	BMN-673	PARP1	9	24	2.30258509299405	NA	2.48830372404841	1.67994332093319	0.808360403115215	0.779730919635072	1.48663482928462	0.603079872575369	1.0367171324866	0.543751826064914	0.297102336844603	NA	NA	0.0322577651366082	0.0530074784142478	73.9866154159401
a3808	TP53_mut	1239	YK 4-279	RNA helicase A	16	8	2.30258509299405	NA	1.70347824899121	1.30157095594292	0.401907293048295	0.930076659170568	1.26633723426095	0.383196372989757	0.432122760081638	0.317377774398976	0.297150291771356	NA	NA	0.278706821727048	0.442637831025234	73.9866154159401
a3809	gain_cnaOV95_(MECOM)	1026	17-AAG	HSP90	8	25	0	NA	0.234976786514928	-0.775891020627642	1.01086780714257	2.50498612039467	2.19945318057366	0.444916638255987	0.403542278702647	0.459599602333393	0.297373899716745	NA	NA	0.0583287108016265	0.329243783730101	73.9866154159401
a3810	loss_cnaOV36	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.83043586181266	2.31308399495339	0.517351866859267	0.767207689541796	0.870430818201948	0.598833279021567	0.674330919660423	0.594362993635684	0.297384054400086	NA	NA	0.603361585097224	0.364775203825387	73.9866154159401
a3811	loss_cnaOV16, loss_cnaOV17	1042	BIRB 0796	p38, JNK2	6	27	2.30258509299405	NA	4.71893211650175	4.32606888644352	0.392863230058228	1.13205700448964	0.788546494710054	0.46037437010543	0.347034847627077	0.498211878048716	0.297397730465519	NA	NA	0.867925331038943	0.449532854219946	73.9866154159401
a3812	loss_cnaOV85	291	KIN001-266	MAP3K8 (COT)	7	25	2.99573227355399	NA	3.69393321425599	3.19282342608654	0.501109788169447	0.497073304117481	1.19923802757235	0.457457354295316	1.00812050057513	0.417856819620587	0.297413325700354	NA	NA	0.950299563086687	0.112569249279159	73.9866154159401
a3813	gain_cnaOV19	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	2.27621040833137	1.4685518288766	0.807658579454768	0.906856633925045	1.04176056329036	0.783961925592384	0.89061330009692	0.775282351737149	0.297424711314923	NA	NA	0.278720879618167	0.257610844244618	73.9866154159401
a3814	SMAD4_mut	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.81304084072152	2.29709214557858	0.515948695142943	0.858910557027808	0.860107630551512	0.599948715835186	0.60070130809469	0.599865268968849	0.297592045038559	NA	NA	0.603367494636959	0.325356313738013	73.9866154159401
a3815	loss_cnaOV35	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	0.978829148758045	0.577072674823223	0.401756473934821	0.746365597800763	0.578783441127823	0.665356924280839	0.538283751446523	0.694139544061515	0.297649972540293	NA	NA	0.0139717883315321	0.305953348469325	73.9866154159401
a3816	loss_cnaOV52, loss_cnaOV53	1039	SL 0101-1	RSK, AURKB, PIM3	9	24	2.30258509299405	NA	5.17321117389622	4.84933250220519	0.323878671691029	0.708363204155438	0.845078215217914	0.398863614677282	0.457221196401895	0.383252894062016	0.297691582279483	NA	NA	0.945312640866487	0.283361314598657	73.9866154159401
a3817	PIK3CA_mut	1047	Nutlin-3a	MDM2	7	26	2.07944154167984	1.38629436111989	2.87221643638101	3.98340776707479	-1.11119133069378	1.54716442105808	1.49058408845566	0.739954863165564	0.718211533027534	0.745473763808286	0.297806984405493	NA	NA	0.160198316906323	0.122553057817032	73.9866154159401
a3818	loss_cnaOV40	308	XL-880	MET	7	25	1.63315443905142	NA	-0.140853190583355	0.363404846270128	-0.504258036853483	0.424905066562111	1.0465956173897	0.527910721886029	1.18675458716794	0.481807900276846	0.297824868275066	NA	NA	0.362302690672693	0.067320003795011	73.9866154159401
a3819	loss_cnaOV16, loss_cnaOV17	1059	AZD8055	MTORC1/2	6	27	0.693147180559945	NA	0.827855762005809	0.159628143729819	0.66822761827599	1.10701872528697	1.11872430630431	0.598317450555795	0.603628107648106	0.597312147872671	0.297877912305757	NA	NA	0.142070143151582	0.221258703523198	73.9866154159401
a3820	gain_cnaOV4_(KRAS)	1028	VX-702	p38	5	26	0.693147180559945	NA	3.71654798611602	3.25205022846494	0.464497757651082	0.813841164336282	0.93210192565342	0.506707732095949	0.570747435747978	0.498333653077115	0.297974660435527	NA	NA	0.512615210232361	0.296163329331734	73.9866154159401
a3821	gain_cnaOV18_(CCNE1)	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.45557107812509	2.06837988928034	0.387191188844753	0.2446425704336	0.571377685878802	0.706122761457428	1.58268116688973	0.677644924563755	0.298070028885354	NA	NA	0.0400157800658164	0.0414290201482137	73.9866154159401
a3822	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	308	XL-880	MET	7	25	1.63315443905142	NA	0.602374813386877	0.155301005158463	0.447073808228415	0.585756408831988	1.03301351603483	0.465521172185186	0.763241855295941	0.432786020016934	0.298338018284569	NA	NA	0.362321775183766	0.157462064125732	73.9866154159401
a3823	loss_cnaOV20	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.28663148089888	4.87534725762486	0.411284223274014	0.939467283648558	0.790649586709364	0.506890290459222	0.437784508766214	0.520185212498186	0.298702429305476	NA	NA	0.945316830136752	0.398175000475267	73.9866154159401
a3824	gain_cnaOV95_(MECOM)	276	CAY10603	HDAC6	8	23	2.99573227355399	NA	0.85285750540754	1.63504512307766	-0.782187617670116	0.873996404642874	1.9719797978489	0.441805765165663	0.894955189191799	0.39665092843413	0.298704104992933	NA	NA	0.610017033653051	0.139997197214776	73.9866154159401
a3825	gain_cnaOV94	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	4.21585798982468	3.75296133794313	0.462896651881543	0.928477836116993	0.85676328360097	0.531528324168557	0.498554336867569	0.540285351557073	0.298835106525143	NA	NA	0.938746648070184	0.354567775826887	73.9866154159401
a3826	ARID1A_mut	1133	JNJ-26854165	MDM2	9	24	2.30258509299405	NA	2.65589166640665	3.22234340223078	-0.566451735824131	0.645618562299207	0.959091289163486	0.637291379981648	0.877378329716631	0.590612950221023	0.298864840128533	NA	NA	0.23330889819683	0.0646629402813518	73.9866154159401
a3827	loss_cnaOV34	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.28827200392356	2.7940899029372	0.494182100986363	1.92566462908188	0.924854242841123	0.462714430654899	0.256629370204499	0.534335118005461	0.298874923834825	NA	NA	0.300837383638011	0.646291780316399	73.9866154159401
a3828	loss_cnaOV35	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.45690415072152	2.56873500169783	0.888169149023695	2.08407566422527	1.16384698480983	0.67996241664184	0.426169339371784	0.763132233545992	0.298920986486883	NA	NA	0.939748218776088	0.540525519370664	73.9866154159401
a3829	loss_cnaOV58	1023	GW 441756	NTRK1	5	26	0.693147180559945	NA	1.74091104810378	2.4056912502825	-0.664780202178723	1.07462807023728	1.26657691754798	0.535307362425077	0.618614216946649	0.524863664392133	0.298948731810456	NA	NA	0.842504530689819	0.262719465754658	73.9866154159401
a3830	loss_cnaOV35	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	3.94819818694659	3.20168074546291	0.746517441483682	1.27596344916703	0.895911228654498	0.787000859898721	0.585061775845554	0.83324934168402	0.299152225299633	NA	NA	0.18026541954063	0.420085300393248	73.9866154159401
a3831	loss_cnaOV39	277	ABT-869	VEGFR and PDGFR family	9	23	0.0237165266173161	NA	2.6133555511402	2.75621512019371	-0.142859569053515	0.809597764541776	0.452929999659402	0.250505034187348	0.17645746481819	0.315412026496245	0.299456575146892	NA	NA	0.130921934333642	0.628099164244412	73.9866154159401
a3832	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.76468095802298	1.13732858265356	1.62735237536942	1.43398701424189	2.34417321052161	0.709162230220613	1.1348445691677	0.694211659814724	0.299489037502278	NA	NA	0.35754083324102	0.173420233690617	73.9866154159401
a3833	gain_cnaOV49	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	1.7375571399474	2.35360282138859	-0.616045681441194	0.770585040967589	0.896658579369558	0.693324817036079	0.799451908212042	0.687045990096182	0.299513320322426	NA	NA	0.589611509522875	0.297987187281144	73.9866154159401
a3834	loss_cnaOV70	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.38579342754812	0.693347599624478	0.692445827923642	0.39755434169782	1.06688772722676	0.668506481148052	1.74176396858462	0.649033455210482	0.299651205356186	NA	NA	0.769140023487841	0.0635288547448785	73.9866154159401
a3835	loss_cnaOV59	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.50558259862897	5.7517089103498	0.753873688279175	0.416343484706627	1.31734318194817	0.590252021130578	1.8107012982571	0.572268258271395	0.299724451295138	NA	NA	0.566145409612965	0.0604631681966805	73.9866154159401
a3836	loss_cnaOV84	1527	GDC0941 (rescreen)	PI3K	5	26	1.38629436111989	NA	0.763265227369295	0.309015110299147	0.454250117070148	0.655539671074453	0.936047877947997	0.503293456891017	0.692940697739339	0.485285130997738	0.299738427973555	NA	NA	0.908479156802212	0.227526853778032	73.9866154159401
a3837	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1170	CCT018159	HSP90	8	25	2.30258509299405	NA	4.10423458239871	3.56399097914001	0.540243603258706	1.19583748749696	1.21523245776662	0.44615780050966	0.451770084904686	0.444559886304861	0.299794219864042	NA	NA	0.192914664474101	0.289644666141616	73.9866154159401
a3838	gain_cnaOV49	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.3516578439286	0.250535613973055	1.10112222995555	0.702095024117612	1.70549317101528	0.664957233884615	1.56833789178243	0.645632740528685	0.299816038790548	NA	NA	0.835118448388159	0.0849470279632007	73.9866154159401
a3839	loss_cnaOV58	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.55882822958854	3.60285628038104	0.955971949207501	1.50772249899523	1.53656852633732	0.623645585056226	0.634050330776767	0.622147293024558	0.299907084361181	NA	NA	0.160262598812377	0.24391191499662	73.9866154159401
a3840	loss_cnaOV36	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.12043518585807	4.05174107591087	1.06869410994721	0.753759116216025	1.47095400277229	0.745076485218295	1.41781915064882	0.726531290531893	0.299963715243067	NA	NA	0.0897003639796481	0.108855096697434	73.9866154159401
a3841	loss_cnaOV41	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.285662132285	4.87552035559163	0.410141776693368	0.95567714031722	0.78785982784297	0.505432977551196	0.429163531689403	0.520577090237318	0.300055304750518	NA	NA	0.945322407947229	0.406221064253877	73.9866154159401
a3842	loss_cnaOV21, loss_cnaOV22	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.62818948993555	1.58589293213468	1.04229655780087	1.27817534816469	1.47541628885979	0.712391882295621	0.815456626743335	0.706442355063303	0.300139952059364	NA	NA	0.320495195409777	0.290343139710507	73.9866154159401
a3843	KRAS_mut	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	3.12722114395333	4.12873250319903	-1.00151135924569	1.39607316095933	1.73977145964086	0.598110207416455	0.717377417783385	0.575656850614409	0.300151855445651	NA	NA	0.142277356584089	0.14128228160643	73.9866154159401
a3844	ARID1A_mut	1020	Lenalidomide	TNFA	9	22	1.6094379124341	NA	3.94588820206988	4.58566714024268	-0.639778938172801	0.767318911484074	0.698541161564648	0.890842964954769	0.8337849212336	0.915878653077183	0.300381837599214	NA	NA	0.0406280740525942	0.0488041657639869	73.9866154159401
a3845	gain_cnaOV95_(MECOM)	1091	BMS-536924	IGF1R	8	24	1.38629436111989	NA	2.69382087227635	2.29343753259322	0.400383339683128	0.909073350022312	0.940615164549955	0.428974142782241	0.440430180549568	0.425661157477399	0.300388213031437	NA	NA	0.731610560297229	0.305240161744547	73.9866154159401
a3846	gain_cnaOV18_(CCNE1)	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.89548873543544	3.1416252362873	0.753863499148133	0.447720043412244	1.05149127171936	0.74999164168646	1.6837832262381	0.716946987030566	0.300479636615938	NA	NA	0.557619426460002	0.0750770081667569	73.9866154159401
a3847	gain_cnaOV19	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.89548873543544	3.1416252362873	0.753863499148133	0.447720043412244	1.05149127171936	0.74999164168646	1.6837832262381	0.716946987030566	0.300479636615938	NA	NA	0.557619426460002	0.0750770081667569	73.9866154159401
a3848	loss_cnaOV57_(ZNRF3)	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.42787219339369	2.54852201343507	0.879350179958623	1.92306274981142	1.66440601691792	0.51996644535323	0.457265463669791	0.528326724982025	0.300481917872165	NA	NA	0.63600890751414	0.437476255655165	73.9866154159401
a3849	loss_cnaOV54	345	KIN001-270	CDK9	10	22	2.99573227355399	NA	5.44575379152942	5.07491097110753	0.370842820421895	0.657196379639286	0.796189910875554	0.489771182554378	0.564280072001369	0.465771815689158	0.300517880583324	NA	NA	0.327683673745501	0.181492013545158	73.9866154159401
a3850	loss_cnaOV102	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.42191525306447	3.73675387119275	0.685161381871721	1.28463160647024	0.99734169528292	0.672374612383925	0.533352424477805	0.686987604260702	0.300634776777666	NA	NA	0.71381146994468	0.455281406940184	73.9866154159401
a3851	gain_cnaOV51_(MYC)	1192	GSK269962A	ROCK1, ROCK2	8	24	1.6094379124341	NA	3.01983912715921	2.24625634439696	0.773582782762247	0.999727229737788	1.53600204977917	0.541350384330027	0.773793850713804	0.503633952098868	0.300698337496695	NA	NA	0.234424974421303	0.118194814966964	73.9866154159401
a3852	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-0.875898713256118	-2.41548317297286	1.53958445971674	3.69571720804396	2.45245274843766	0.585524757628041	0.416586111179106	0.627773342706617	0.300804667120165	NA	NA	0.406354490276812	0.550407719453496	73.9866154159401
a3853	NF1_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.086253940984	4.57468862752307	-0.488434686539075	0.784905890426528	0.927937091868312	0.534287732553071	0.622284394214004	0.526366162985961	0.300861203602945	NA	NA	0.523129990626871	0.315851904642154	73.9866154159401
a3854	MLL2_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-0.79347315006618	-0.286476003030761	-0.506997147035419	1.67165682408095	1.39091785286947	0.359389694930407	0.303290208691105	0.364505456587161	0.301065060128465	NA	NA	0.887641915407009	0.656277249340437	73.9866154159401
a3855	loss_cnaOV33_(ZFHX3)	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.75542414057881	4.40857836670409	0.346845773874712	0.812454528134701	0.510695658147107	0.632474134396915	0.42691099854047	0.679163349720123	0.301080146159144	NA	NA	0.358980550507394	0.46125888530132	73.9866154159401
a3856	gain_cnaOV48_(SOX17)	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	2.52127985651262	3.76267610834286	-1.24139625183025	2.54243954437974	1.96590823038302	0.617764882895692	0.488269722902339	0.631461953637775	0.301088905528115	NA	NA	0.744366452042964	0.48951578090576	73.9866154159401
a3857	gain_cnaOV95_(MECOM)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	8	23	-1.6094379124341	NA	0.969548375797847	0.425239294731317	0.544309081066529	0.593899288086953	1.33359718102131	0.454486355737792	0.916500645791036	0.408151043518014	0.30113603035755	NA	NA	0.425043768577024	0.129983962922256	73.9866154159401
a3858	loss_cnaOV81_(RB1)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.87168281128139	2.09123986895935	0.780442942322033	0.690299348353296	1.32496610514809	0.604408824414373	1.13058623651286	0.589028609327936	0.30121860671963	NA	NA	0.682705027864716	0.175474654192227	73.9866154159401
a3859	loss_cnaOV35	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	-0.143438789530102	1.05440188113329	-1.19784067066339	1.11396003092988	2.15911100155899	0.586369506311037	1.07529950573136	0.554784200441055	0.301360333289863	NA	NA	0.409813283742562	0.0960323378658581	73.9866154159401
a3860	gain_cnaOV18_(CCNE1)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-1.54291246532036	-2.20366735083592	0.660754885515559	1.37289566039347	1.2748569625293	0.514337580523705	0.481285580964097	0.518297271722651	0.301439387550866	NA	NA	0.603247862468117	0.41748894961651	73.9866154159401
a3861	loss_cnaOV36	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.893725508534777	0.226481128265025	-1.1202066367998	1.12223982746078	1.63061357948026	0.699803255961768	0.998188274367719	0.6869847343948	0.301446621774695	NA	NA	0.456166754568716	0.216495227731505	73.9866154159401
a3862	gain_cnaOV18_(CCNE1)	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.38690619854596	3.92169375245084	0.465212446095117	0.259273974186451	0.787095758550944	0.619298638660262	1.79428902401353	0.591049362216842	0.301636038200043	NA	NA	0.520473821801884	0.0340679128431112	73.9866154159401
a3863	loss_cnaOV54	1022	AZD7762	CHEK1, CHEK2	10	21	0.693147180559945	NA	-0.503178690080099	-0.964128597289184	0.460949907209084	0.921992961236178	0.710584024022522	0.58920027958339	0.499949486155575	0.64869162776797	0.301813290381409	NA	NA	0.0751804196937573	0.184060891310479	73.9866154159401
a3864	SMARCA4_mut	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	-0.0717187304175286	0.935430073169741	-1.00714880358727	0.758405436611249	1.35351622924657	0.761132772055001	1.32798204623568	0.744098062383702	0.301895821457827	NA	NA	0.158477506380706	0.12680887935572	73.9866154159401
a3865	SMAD4_mut	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.74745678169883	4.01539103364237	0.732065748056459	1.8918641465018	1.02921349016283	0.660814746029744	0.386954713111987	0.711286584419563	0.301959687920615	NA	NA	0.817433636554686	0.573502135862864	73.9866154159401
a3866	loss_cnaOV20	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.12211115051317	3.63587414493689	-0.513762994423716	0.941378088682673	0.949497090768071	0.541704906566139	0.545756270089795	0.541089593026684	0.302021747886464	NA	NA	0.725241237093069	0.308510587936475	73.9866154159401
a3867	KRAS_mut	1375	Temozolomide	DNA akylating agent	7	26	3.40119738166216	NA	5.69759365219324	6.01443018958828	-0.316836537395043	0.569594827691998	0.722531859757718	0.455512548520872	0.556248972061186	0.438508742716599	0.302219858107841	NA	NA	0.907609544239645	0.242917601903178	73.9866154159401
a3868	loss_cnaOV34	309	Y-39983	ROCK	5	27	2.99573227355399	NA	4.51668469983341	5.04717939182986	-0.530494691996445	1.75768171816129	1.12903426001317	0.430758433226037	0.301814991027724	0.469865894052016	0.302309009080893	NA	NA	0.366777135955091	0.54626115079632	73.9866154159401
a3869	ARID1A_mut	1529	MLN4924	NEDD8-activating enzyme	5	12	0	NA	0.844001387135121	1.53924651050139	-0.695245123366267	1.09323210099698	1.56130629904687	0.479042311329396	0.635953813222492	0.445297071939498	0.302317147713944	NA	NA	0.852778599402732	0.318524601777848	73.9866154159401
a3870	gain_cnaOV18_(CCNE1)	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	3.49933068751591	2.68736444682446	0.81196624069146	1.2444746136993	1.203265042411	0.672464049752208	0.652457054369173	0.67480248496583	0.302355095243389	NA	NA	0.0909512055417231	0.290028537715611	73.9866154159401
a3871	loss_cnaOV58	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.74747027963655	4.29611643872587	0.451353840910677	1.05628802431753	1.05796598681917	0.426714326351928	0.427301863241606	0.426624150997231	0.302465569289034	NA	NA	0.345976763893986	0.41633034574371	73.9866154159401
a3872	loss_cnaOV35	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.58090064884129	3.9920076695007	0.588892979340595	1.3574001343674	1.06413567092414	0.531620172100925	0.433838898664203	0.553400281027301	0.302512859577834	NA	NA	0.817441290446156	0.400549056968157	73.9866154159401
a3873	loss_cnaOV83	1019	Bosutinib	SRC, ABL, TEC	5	26	0.693147180559945	NA	2.60900618480027	1.55320499536364	1.05580118943663	1.1437025859439	1.6186490150453	0.676037213937536	0.923143133898996	0.652273086767416	0.302540644831454	NA	NA	0.0388713559661946	0.120057370097445	73.9866154159401
a3874	loss_cnaOV85	330	XMD13-2	RIPK	7	25	2.32630161961136	NA	4.48859187321511	3.97074268832878	0.517849184886336	1.11515788963663	1.10580248549033	0.467507978346271	0.464372973279213	0.468301700964899	0.302601976872761	NA	NA	0.817442521788517	0.303240267286808	73.9866154159401
a3875	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.85025263781223	4.30147567641293	0.548776961399305	1.02741723921404	0.963212213663462	0.564574926555115	0.534132522264385	0.56973629862115	0.302653613348378	NA	NA	0.506310861571676	0.315024028255663	73.9866154159401
a3876	NF1_mut	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	0.872997865169897	1.72596072266367	-0.852962857493775	0.559419458051158	1.30461831262151	0.695609547302027	1.52472861860263	0.653802609730218	0.30269164281076	NA	NA	0.156740178462571	0.0607492589830581	73.9866154159401
a3877	loss_cnaOV57_(ZNRF3)	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.7544948118772	4.40871112794718	0.345783683930019	0.63108902644431	0.538512120860239	0.630447458966408	0.547915855672912	0.642109379780815	0.302784304474392	NA	NA	0.359042949181524	0.361032723148809	73.9866154159401
a3878	loss_cnaOV35	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.99951254216695	1.97796903706572	1.02154350510122	0.514019142606392	1.59969421471936	0.675195838834225	1.98736471159687	0.638586734703193	0.302806545115477	NA	NA	0.946518916570259	0.0647978547019584	73.9866154159401
a3879	loss_cnaOV35	1020	Lenalidomide	TNFA	5	26	1.6094379124341	NA	4.21735029961697	4.43503536176473	-0.217685062147766	1.09272268070232	0.709840517083536	0.281248417222061	0.199213456435126	0.30666756392288	0.302809332879176	NA	NA	0.0406643921378169	0.687384084833251	73.9866154159401
a3880	MLL2_mut	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	2.26941188582268	3.14770103312435	-0.878289147301662	0.416064918865737	0.912395201551119	0.988198794226778	2.11094256563621	0.962619209097686	0.302836259299858	NA	NA	0.233444931597146	0.0360701053715152	73.9866154159401
a3881	gain_cnaOV19	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.399812225837112	-0.112370501872665	0.512182727709777	1.32331309811436	0.950384810029714	0.511419410961147	0.387045762971442	0.538921416151173	0.302867183397271	NA	NA	0.181094349661379	0.577801806522438	73.9866154159401
a3882	loss_cnaOV87, loss_cnaOV88	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.99951018348087	1.08471025213978	0.914799931341091	1.66917331150242	1.46631298817654	0.618007869242082	0.548055690225289	0.623877670536567	0.302976226657811	NA	NA	0.810892414767878	0.4452666619446	73.9866154159401
a3883	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	341	EX-527	SIRT1	5	26	2.99573227355399	NA	6.06597156882087	5.71703280005692	0.348938768763947	0.522434050557895	0.558535437123461	0.630199304874879	0.667909697676335	0.624738817936124	0.302976279950212	NA	NA	0.106374176526281	0.225774767944497	73.9866154159401
a3884	gain_cnaOV49	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.10012335548419	4.44111840314612	-0.340995047661932	0.608260380699705	0.630341327147295	0.542214397801882	0.560607033569525	0.540968889355798	0.303119754275421	NA	NA	0.265397697738149	0.437932594997016	73.9866154159401
a3885	loss_cnaOV52, loss_cnaOV53	298	OSI-930	KIT, VEGFR, PDGFR	8	24	2.32630161961136	NA	4.87784660061771	4.30947263029864	0.568373970319073	0.822357744334208	0.997164576658256	0.592531527343589	0.691151721054486	0.569990133648584	0.303189953514578	NA	NA	0.0294265287476357	0.130859611265423	73.9866154159401
a3886	loss_cnaOV55	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	-1.38629436111989	0.693147180559945	-2.57933568412009	-1.9777327025025	-0.601602981617591	1.58019257096189	1.17302969769374	0.471337634408676	0.380714979093582	0.512862532636968	0.303196233813631	NA	NA	0.603295114669447	0.345154787446087	73.9866154159401
a3887	loss_cnaOV40	293	MP470	PDGFR	7	25	2.99573227355399	NA	4.59721538406527	3.89581038371568	0.701405000349587	1.99001789119086	1.69251033419012	0.399422281836201	0.352461655472783	0.414416967613503	0.303211742817629	NA	NA	0.617943800334395	0.418190880530244	73.9866154159401
a3888	ARID1A_mut	291	KIN001-266	MAP3K8 (COT)	8	24	2.99573227355399	NA	3.55870487907009	3.21701996330811	0.341684915761972	1.62638032155878	0.888467091894023	0.309045741192795	0.210089184696043	0.384578020817375	0.303244905933585	NA	NA	0.9503220930604	0.585673448080462	73.9866154159401
a3889	gain_cnaOV72_(ASXL1)	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	2.74916176858597	3.47165596092683	-0.722494192340866	1.28719810153524	0.848732435247746	0.767735026320363	0.561292151906645	0.851262615090196	0.303295552629188	NA	NA	0.180508487632416	0.351907909988181	73.9866154159401
a3890	gain_cnaOV26	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	4.08390226154295	3.50094658211148	0.582955679431473	0.819221281230486	0.960511455856156	0.612512537849352	0.711597333697022	0.606922151607085	0.303379292682426	NA	NA	0.725268758854456	0.343564224213123	73.9866154159401
a3891	loss_cnaOV1	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.3810514774906	0.693838146182152	0.687213331308447	0.393676827790524	1.06731884837016	0.663252697149874	1.74562809593181	0.643868823602103	0.303516625069719	NA	NA	0.769207056262982	0.0632517847402616	73.9866154159401
a3892	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	2.13051031524177	1.22499998597967	0.905510329262102	0.806531705597351	1.22040310160112	0.756311957236683	1.12272130528513	0.74197642407997	0.303560924849641	NA	NA	0.0936459576253069	0.177262174723223	73.9866154159401
a3893	gain_cnaOV51_(MYC)	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	0.0584097380043601	-0.774582455085087	0.832992193089447	1.95753180894185	1.26419253918323	0.57159330699391	0.42553188115994	0.658912441950994	0.30356345541902	NA	NA	0.907136573022684	0.413555486164919	73.9866154159401
a3894	loss_cnaOV20	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.86980359690327	4.33031320430944	0.539490392593826	0.663768091383302	0.765505984596959	0.71397345790012	0.81276939882651	0.704750065249808	0.303890744783463	NA	NA	0.0406804575153376	0.20699159730029	74.0237215843648
a3895	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	7	25	0.246860077931526	2.32630161961136	1.55229151345426	0.850705893995536	0.701585619458724	1.46922300211901	1.54860615149008	0.45763789542414	0.477521532433708	0.453043285914663	0.304221037285796	NA	NA	0.788510207347182	0.29552818519999	74.0237215843648
a3896	PTEN_mut	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-4.93178610147398	-3.50737261771851	-1.42441348375547	2.02846304462676	1.62611220448998	0.851804721841248	0.702213179347106	0.875962605669162	0.304343262732352	NA	NA	0.239389820614415	0.258081935139201	74.0237215843648
a3897	gain_cnaOV96	134	Etoposide	TOP2	4	15	2.77258872223978	NA	2.99852147426736	2.09258794517431	0.905933529093054	1.07695232618471	1.93332992490804	0.500002126488847	0.841201144253505	0.468587134260671	0.304414232346753	NA	NA	0.398756146048186	0.248677719652078	74.0237215843648
a3898	loss_cnaOV33_(ZFHX3)	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.61135698656798	1.84334238047	0.76801460609798	0.850730585517899	1.37008221101714	0.578619119463008	0.90277065286237	0.560560964825469	0.3044524457772	NA	NA	0.837109961177112	0.177895217749601	74.0237215843648
a3899	SMARCA4_mut	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	1.61248684641942	2.97156619691181	-1.35907935049239	3.26634260981712	1.6728372309441	0.745544636830334	0.416085975306945	0.81243968352221	0.304538283173198	NA	NA	0.340556355856643	0.547402546542592	74.0237215843648
a3900	gain_cnaOV49	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	2.80204048927761	3.47280098907353	-0.670760499795919	0.759507787437376	1.24090785446737	0.552173375099486	0.883151576442822	0.540540135499285	0.304597721510586	NA	NA	0.32097255815779	0.262434006138547	74.0237215843648
a3901	PIK3CA_mut	1023	GW 441756	NTRK1	7	24	0.693147180559945	NA	2.7002393000214	2.18128552698809	0.518953773033309	0.680000083949919	1.35685204565317	0.416054651785504	0.763167219066887	0.38246894692449	0.304684688805482	NA	NA	0.842575945265831	0.184282388190204	74.0237215843648
a3902	loss_cnaOV57_(ZNRF3)	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	1.6606410290859	2.37015896778279	-0.709517938696883	1.91829613790185	1.77494286760163	0.396529866137942	0.369868825088145	0.399741282746533	0.304746292566525	NA	NA	0.106579730643545	0.525193863714872	74.0237215843648
a3903	NF1_mut	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	2.12265132578762	1.4856656420857	0.636985683701921	2.60590752599173	1.47034203682955	0.393171786375316	0.244439097453968	0.433222792892075	0.304930026243582	NA	NA	0.0754284771241297	0.662653483001195	74.0237215843648
a3904	loss_cnaOV42	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	4.32723908182762	3.72580898915974	0.601430092667884	1.21543057372496	0.994994289571518	0.590108469017243	0.494828833229582	0.604455823487069	0.305047137524939	NA	NA	0.713904219845502	0.403492475695249	74.0237215843648
a3905	loss_cnaOV36	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.38220348148979	4.68921733397186	0.692986147517927	0.197243483503194	1.26343088510863	0.567934826798354	3.51335382649894	0.548495494043857	0.305050239160061	NA	NA	0.419112722756009	0.0150350231965138	74.0237215843648
a3906	gain_cnaOV94	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.16350397695467	2.11827457148876	1.04522940546591	1.1965325951187	1.87574917951405	0.577753904273874	0.873548626865635	0.557233033542735	0.30505551526236	NA	NA	0.398797652143798	0.276535509127464	74.0237215843648
a3907	gain_cnaOV49	326	GSK690693	AKT	3	29	2.32630161961136	NA	3.51974476947846	4.21732973967428	-0.697584970195821	0.974672656966086	1.48326598563521	0.479472278938953	0.715712054924399	0.470303355535441	0.305173215117632	NA	NA	0.0898230242795934	0.345254890931979	74.0237215843648
a3908	loss_cnaOV54	1495	AZD-2281	PARP1, PARP2	11	22	2.30258509299405	NA	3.44267052450227	3.6205192639466	-0.177848739444336	0.912118505652505	0.924533788711435	0.193198945529371	0.194984246391435	0.192365862249569	0.305176064580599	NA	NA	0.138429674478724	0.604828862603977	74.0237215843648
a3909	loss_cnaOV52, loss_cnaOV53	193	GW-2580	CSF1R (cFMS)	8	24	2.99573227355399	NA	5.96407398791294	5.6472744778903	0.316799510022636	0.285583910797187	0.658310465341968	0.534510412848278	1.10930447425527	0.481231161740791	0.305222337354998	NA	NA	0.187149761336298	0.0700691241961985	74.0237215843648
a3910	gain_cnaOV4_(KRAS)	1494	SN-38	TOP1	7	25	-2.99573227355399	NA	-4.65713960209064	-4.05081010842311	-0.606329493667532	0.865199794373152	1.41725898616049	0.457478514050969	0.700797084801465	0.427818415397842	0.305301623277516	NA	NA	0.212331016948944	0.180143505128294	74.0237215843648
a3911	SMAD4_mut	333	T0901317	LXR	3	29	2.32630161961136	NA	5.51497061568331	4.67456359303603	0.840407022647277	0.930479486949486	1.11122402049188	0.763937872640977	0.903197796871905	0.756289467424645	0.305370950813571	NA	NA	0.00466038609372463	0.25240377674198	74.0237215843648
a3912	gain_cnaOV49	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	3.77525911180056	4.27473099839132	-0.499471886590767	0.712858924473769	0.990646114899092	0.512218263926086	0.700660214024081	0.504188003242352	0.305485239515787	NA	NA	0.204425371049035	0.351686705024102	74.0237215843648
a3913	loss_cnaOV87, loss_cnaOV88	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.22520596347413	-2.40555945564378	1.18035349216965	1.34555605260499	1.6062066376684	0.742043398554234	0.877223575996327	0.734870261701246	0.305552396122189	NA	NA	0.120146176856876	0.263058841256486	74.0237215843648
a3914	loss_cnaOV55	155	AP-24534	ABL	4	15	-0.669430653942629	NA	1.31457863497495	0.648276762262974	0.666301872711978	0.671410837277142	1.33355806247268	0.536208479995519	0.992390702858055	0.499642191414241	0.305588537701632	NA	NA	0.575837016273775	0.195399529680058	74.0237215843648
a3915	gain_cnaOV26	192	LFM-A13	BTK	3	16	2.77258872223978	NA	4.34146471406847	4.79701411624795	-0.455549402179477	1.31921284232151	0.536850435701925	0.672369006748032	0.345319108156811	0.848559248319975	0.305627471395944	NA	NA	0.955942077041691	0.612385995510344	74.0237215843648
a3916	loss_cnaOV81_(RB1)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-1.18648837493823	-2.10060475708865	0.914116382150412	1.97594969065924	2.03187949644655	0.451073706533671	0.462621283563871	0.449887103909983	0.305670751666024	NA	NA	0.272830653757467	0.436958104261632	74.0237215843648
a3917	loss_cnaOV38	1011	ABT-263	BCL2, BCL2L1, BCL2L2	8	25	0.693147180559945	NA	2.10550176303034	1.62012019626597	0.48538156676437	1.20412012506728	1.82088188330056	0.285305287373116	0.403100618169014	0.266564004626461	0.30577259531316	NA	NA	0.223991029421707	0.397580766336052	74.0237215843648
a3918	loss_cnaOV54	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	11	22	1.6094379124341	NA	2.85367306010318	2.08902639813075	0.764646661972438	1.50229308023604	1.52970331738167	0.50275427680375	0.508986343631627	0.499865989230676	0.30577778565733	NA	NA	0.236811753725933	0.185561598029454	74.0237215843648
a3919	loss_cnaOV40	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.57247981650626	4.25844323534325	0.314036581163008	0.82293011942462	0.492490824379021	0.544626299299684	0.38160783491869	0.637649608109907	0.305942250967393	NA	NA	0.248250051998622	0.3674405876458	74.0237215843648
a3920	SMAD4_mut	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.07170504203832	4.49086209675841	-0.419157054720093	2.40625236632693	0.790212218776399	0.425850874007108	0.174194968319106	0.530436058517463	0.306025027286146	NA	NA	0.0294589408832054	0.791904476261349	74.0237215843648
a3921	gain_cnaOV49	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	3.01958235296477	3.97768944740701	-0.958107094442236	0.499268257448161	1.62890170486267	0.607477797269477	1.91902264994629	0.588192087700598	0.306218997138672	NA	NA	0.712201082142291	0.0513723150023083	74.0237215843648
a3922	loss_cnaOV82	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.22629309355644	1.46366608427621	0.762627009280231	2.22913781912723	0.835044932354547	0.725773844827629	0.342117478218023	0.913276615103667	0.306273728322304	NA	NA	0.446254586665453	0.614827539334981	74.0237215843648
a3923	loss_cnaOV20	341	EX-527	SIRT1	5	26	2.99573227355399	NA	6.06443559859589	5.71732817894634	0.34710741964955	0.522015579408615	0.558789394398946	0.626703432674482	0.664936897176103	0.62117753688384	0.306279321286254	NA	NA	0.106461544053171	0.227647254027172	74.0237215843648
a3924	gain_cnaOV26	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-1.09575602436303	-0.704856058956232	-0.390899965406796	0.222228529500719	0.953430301724292	0.423103341574013	1.75899991906994	0.409993226248261	0.30635278140239	NA	NA	0.0397594026076749	0.0936991368880016	74.0237215843648
a3925	gain_cnaOV49	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	1.43113673460591	2.38625717005944	-0.955120435453532	1.12261650048985	1.41075215122364	0.68575772035647	0.850798500678339	0.677029224889073	0.306573326283219	NA	NA	0.524828075535559	0.274505372737931	74.0237215843648
a3926	gain_cnaOV51_(MYC)	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	2.8806707436636	2.11031958766652	0.77035115599708	1.61749370520816	1.02763608735361	0.64574768223402	0.476262228110459	0.749634199769014	0.306608638736612	NA	NA	0.378909679821872	0.363461466771522	74.0237215843648
a3927	loss_cnaOV43_(NF1)	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.74517620988644	2.87366604086011	0.871510169026326	0.931250325475852	1.68284694938538	0.543632300098081	0.935849518850906	0.517878449578926	0.306616118481357	NA	NA	0.659662001421872	0.130334804898167	74.0237215843648
a3928	NF1_mut	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.94153691315507	-1.01653092535741	-0.925005987797661	1.02590444340489	1.33284304051364	0.71513980025653	0.90164926543026	0.694009691824769	0.30675906113376	NA	NA	0.0457538219885735	0.177805282056128	74.0237215843648
a3929	loss_cnaOV58	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	3.20916360332815	2.72442027528291	0.484743328045244	1.13451008702209	0.923424300526468	0.508494487391405	0.427271060513546	0.524941056639813	0.306803119638128	NA	NA	0.965800634153886	0.407762347262181	74.0237215843648
a3930	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	151	QS11	ARFGAP	3	16	2.32630161961136	NA	4.7094683403091	3.59002531432286	1.11944302598625	1.68072925912414	1.37460923081274	0.791647720844429	0.666046015388351	0.814371823564996	0.306975629546314	NA	NA	0.0594731378026075	0.36954207075643	74.0237215843648
a3931	loss_cnaOV21, loss_cnaOV22	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.10899323248381	4.05292472625993	1.05606850622388	0.0830078353364968	1.48539579027023	0.735839475086895	12.7225159160313	0.710967752259319	0.307020012793023	NA	NA	0.0898658816603368	0.000729848529869868	74.0237215843648
a3932	gain_cnaOV72_(ASXL1)	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.78319947281203	1.24227616599599	0.540923306816037	1.03891342598717	1.23184371088139	0.445596317476979	0.520662543466559	0.439116831167653	0.307142143488877	NA	NA	0.0937312665273599	0.392200389978724	74.0237215843648
a3933	NF1_mut	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	2.38442734101521	3.11825592591098	-0.733828584895776	1.63444680631485	1.11032084267174	0.624306995319315	0.448976731491387	0.660915797212254	0.307181572004947	NA	NA	0.084855590239081	0.441640027346566	74.0237215843648
a3934	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.11483329964081	8.81759062551461	-0.702757325873804	0.391733366581614	1.26711315590865	0.572763285324222	1.79396851487603	0.554612918820068	0.3073230582397	NA	NA	0.524852055267529	0.0644760578154254	74.0237215843648
a3935	loss_cnaOV81_(RB1)	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	2.5453072241631	1.11054795979892	1.43475926436418	2.28961683428263	2.29528403074393	0.625244278949285	0.626637279601287	0.625090073884735	0.307331115243835	NA	NA	0.357826290307064	0.30756760575046	74.0237215843648
a3936	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	2.00424970413376	1.12876663424286	0.87548306989089	1.25403680232701	1.47870298766084	0.609420315572785	0.69813187959582	0.592061473599791	0.307388123205544	NA	NA	0.852897282700682	0.288017409522742	74.0237215843648
a3937	loss_cnaOV36	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.45982800773833	2.84189097161466	0.617937036123676	1.32393606765791	0.764949353196525	0.740507485441066	0.466742353516232	0.807814312858071	0.3074068911969	NA	NA	0.321680653244392	0.506093098697303	74.0237215843648
a3938	loss_cnaOV36	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.12085072234979	4.53335993132054	0.58749079102925	1.12828145409011	0.920388160655835	0.627871833907706	0.520695247537349	0.638307635998518	0.307497197829857	NA	NA	0.942460477916049	0.464964992335469	74.0237215843648
a3939	loss_cnaOV21, loss_cnaOV22	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	1.83300389758512	2.45151917474803	-0.618515277162909	0.608921223984608	0.950835940216372	0.663676853587459	1.01575581996554	0.65049631697994	0.307506876522928	NA	NA	0.731751058919859	0.210438141087457	74.0237215843648
a3940	gain_cnaOV4_(KRAS)	1020	Lenalidomide	TNFA	5	26	1.6094379124341	NA	4.67762060311338	4.34652184186158	0.331098761251805	0.89841908696879	0.745208110749338	0.431028609732388	0.36853486981105	0.444303754180657	0.307761471544986	NA	NA	0.0407373946120637	0.472943592098317	74.0237215843648
a3941	NF1_mut	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	0.974375950600639	-0.00878550876245128	0.98316145936309	1.94281360964644	1.55684999090664	0.614054624353881	0.506050325405126	0.631506866496843	0.307840370942076	NA	NA	0.456392584432368	0.393947866504135	74.0237215843648
a3942	gain_cnaOV95_(MECOM)	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-2.69635604821271	-3.72798493691345	1.03162888870075	1.79800040799022	1.70458549191095	0.597346192657064	0.573764546501902	0.605208065888335	0.307843441586251	NA	NA	0.674721773346002	0.302377958232274	74.0237215843648
a3943	gain_cnaOV4_(KRAS)	333	T0901317	LXR	8	24	2.32630161961136	NA	5.06600075507883	4.64913541685267	0.416865338226161	0.590340629062545	1.22907788114549	0.374436353042176	0.706143737536986	0.339169180912805	0.308018687680387	NA	NA	0.00466760270785179	0.212949441050843	74.0237215843648
a3944	loss_cnaOV59	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.26490688248342	3.76699823695611	0.497908645527313	0.921874391661988	0.862706774890733	0.571385841420135	0.540104649864138	0.577147021466681	0.308116360344517	NA	NA	0.938810292989797	0.374788131198572	74.0237215843648
a3945	SMAD4_mut	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	5.76521186101356	4.57232817011121	1.19288369090235	2.55405352919995	1.32679304650055	0.783046644459545	0.467055086067839	0.899072914233766	0.308146718167647	NA	NA	0.114163006322833	0.505872572825169	74.0237215843648
a3946	loss_cnaOV85	326	GSK690693	AKT	7	25	2.32630161961136	NA	4.79061915477574	3.97309850702237	0.817520647753371	0.96270630874513	1.52218816228572	0.57251842082757	0.84919008042961	0.537069376840891	0.30818107894563	NA	NA	0.0898926607198887	0.104810507303426	74.0237215843648
a3947	gain_cnaOV94	1049	PD-173074	FGFR1, FGFR3	7	26	0.693147180559945	NA	3.44061034211798	2.86425211054955	0.576358231568427	0.878095947791103	1.00871299048456	0.585262852427191	0.656372726714304	0.571379804766425	0.308215981544063	NA	NA	0.0842877985003508	0.164666544034787	74.0237215843648
a3948	PTEN_mut	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	4.55090508169073	3.47659581609735	1.07430926559338	0.465211579703099	0.86187136428363	1.29314564794335	2.30929175554704	1.24648446405494	0.308313580205647	NA	NA	0.0556484365744591	0.0263588879675931	74.0237215843648
a3949	gain_cnaOV18_(CCNE1)	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.82007053176343	4.24381853762303	0.576251994140394	0.474332890124038	0.807094609766302	0.730666676874788	1.21486830480953	0.713983202424374	0.308466276394255	NA	NA	0.219574638620338	0.152170894475713	74.0237215843648
a3950	gain_cnaOV19	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.82007053176343	4.24381853762303	0.576251994140394	0.474332890124038	0.807094609766302	0.730666676874788	1.21486830480953	0.713983202424374	0.308466276394255	NA	NA	0.219574638620338	0.152170894475713	74.0237215843648
a3951	loss_cnaOV38	1241	CHIR-99021	GSK3B	8	24	2.30258509299405	NA	4.02475791722591	3.56701646626479	0.457741450961122	0.657409832710485	1.13312489239018	0.439400835555142	0.696280201763738	0.4039638119639	0.308483298322905	NA	NA	0.829001271291684	0.177073402999087	74.0237215843648
a3952	loss_cnaOV70	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	2.67677348052387	3.3671654382891	-0.690391957765226	1.37302325057233	1.07413794950201	0.629574450920697	0.502826122920673	0.642740495376134	0.308496874070741	NA	NA	0.950341901608123	0.478263047208407	74.0237215843648
a3953	loss_cnaOV39	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	23	-1.38629436111989	0.693147180559945	-1.83310555661283	-2.24986728127804	0.416761724665206	1.38910641995151	1.24534407505913	0.323388300956005	0.300021451689607	0.334655885880708	0.308510007262334	NA	NA	0.603435879628466	0.426376753778881	74.0237215843648
a3954	loss_cnaOV70	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.11957735645328	4.53349165882707	0.586085697626206	0.352475262729087	0.964017743800844	0.626316711459037	1.66277114906833	0.607961524977164	0.308665452414235	NA	NA	0.942465532292919	0.073569310803674	74.0237215843648
a3955	SMAD4_mut	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	4.03036869335713	3.49409722228729	0.536271471069844	0.733119810037169	0.907776580233988	0.597722606290025	0.731492265967626	0.590752705838275	0.308687710410316	NA	NA	0.659529275727527	0.333066284952273	74.0237215843648
a3956	TP53_mut	1038	NU-7441	PRKDC (DNAPK)	23	10	0.693147180559945	NA	2.64913368872834	2.27923968596661	0.36989400276173	1.03013907226595	1.02566961740447	0.35952407415897	0.359071908560941	0.360636599237259	0.308720002907764	NA	NA	0.389788046325573	0.354811339671111	74.0237215843648
a3957	loss_cnaOV59	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	6.06321741456173	5.67836820408657	0.384849210475165	0.766596615818284	0.572818174046806	0.646759148623002	0.502023101242585	0.671852304818315	0.308782591459216	NA	NA	0.187265033544973	0.3959136304408	74.0237215843648
a3958	loss_cnaOV42	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.38154569516949	3.92245953864748	0.459086156522014	1.06001199475056	0.709137303521284	0.61078579290977	0.433095246842038	0.64738683784139	0.308837993846913	NA	NA	0.52070117064754	0.456091334353473	74.0237215843648
a3959	PIK3CA_mut	291	KIN001-266	MAP3K8 (COT)	6	26	2.99573227355399	NA	3.64463633560304	3.22347308224374	0.421163253359303	1.90967830446858	0.854933978227463	0.381787830958148	0.220541466263608	0.492626640284554	0.308976518459532	NA	NA	0.950343688458788	0.618123180786339	74.0237215843648
a3960	ARID1A_mut	235	QL-XII-47	BTK, BMX	8	24	2.32630161961136	NA	0.622544917229189	1.87953683098819	-1.256991913759	1.00477149441413	1.66311273754706	0.818905070990719	1.25102266609578	0.755806798529453	0.309009725948128	NA	NA	0.0755138849877478	0.0185525959646364	74.0237215843648
a3961	PTEN_mut	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	3.40275789271053	4.56006352599922	-1.15730563328869	0.734663629945522	0.941524575940186	1.245529302405	1.57528641151666	1.22918260750977	0.30902077794162	NA	NA	0.0294927968812006	0.0942244687877763	74.0237215843648
a3962	loss_cnaOV38	1371	PLX4720 (rescreen)	BRAF	8	25	2.30258509299405	NA	4.90379158364576	4.40811148612843	0.495680097517339	0.916087708884538	0.987464297711144	0.510061093318984	0.541083667764626	0.501972677560376	0.309110420836207	NA	NA	0.320082231069729	0.214562527697685	74.0265060571667
a3963	gain_cnaOV50	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.330942417103229	-0.424085145156355	0.755027562259583	0.662624791026976	1.45250699849267	0.540950702703262	1.13944961384466	0.519809930721924	0.309208843363724	NA	NA	0.887708859207702	0.115531642343067	74.0307204281742
a3964	loss_cnaOV54	1011	ABT-263	BCL2, BCL2L1, BCL2L2	11	22	0.693147180559945	NA	1.17888799471577	2.01723868495539	-0.838350690239629	1.16092604484649	1.8583178997159	0.503341845906241	0.722139617731193	0.451134162980294	0.309284065118532	NA	NA	0.224106781178094	0.1235600671352	74.0307204281742
a3965	loss_cnaOV54	134	Etoposide	TOP2	6	13	2.77258872223978	NA	1.53647237919082	2.6280054461184	-1.09153306692758	1.1249619836275	1.98286464471772	0.615246371810011	0.970284403218557	0.550482893441758	0.309406810661463	NA	NA	0.399076306153278	0.147226936921036	74.0414225326583
a3966	SMARCA4_mut	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	9.73386837828671	8.65289862726884	1.08096975101787	2.6243556841961	1.60092991050899	0.639056555075357	0.411899102521613	0.675213664209816	0.309677904542503	NA	NA	0.920838028662123	0.551799558203227	74.064254326835
a3967	gain_cnaOV95_(MECOM)	308	XL-880	MET	9	23	1.63315443905142	NA	-0.0352243728915262	0.365920355595367	-0.401144728486894	0.317902495124822	1.10603936186988	0.417303995522594	1.26184831713695	0.362685761751474	0.30969619007638	NA	NA	0.36273363181301	0.124929273941783	74.064254326835
a3968	gain_cnaOV96	305	TPCA-1	IKK	5	27	2.99573227355399	NA	3.84361600062543	3.22919112454646	0.61442487607897	1.48584679873554	1.17269396185149	0.503997009903358	0.41351832275161	0.523943071309838	0.30994675274543	NA	NA	0.993536125546815	0.421605044708679	74.064254326835
a3969	loss_cnaOV38	1166	QL-VIII-58	MTOR, ATR	7	16	2.30258509299405	NA	-0.581649553207249	-1.43804302262252	0.856393469415274	1.42694063788031	1.215809333547	0.669218442042098	0.600160543950466	0.704381390885388	0.309951988419999	NA	NA	0.0458226898506487	0.196631190170616	74.064254326835
a3970	loss_cnaOV34	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.52914902301661	4.84431545321678	-0.315166430200173	0.736072463242735	0.646562153916036	0.47810478927995	0.428173102430325	0.487449548804091	0.310016470497027	NA	NA	0.75937692746649	0.409956063269881	74.064254326835
a3971	loss_cnaOV54	164	JQ12	HDAC	6	13	1.63315443905142	NA	0.948161445127383	2.18423072469846	-1.23606927957108	1.98392323364458	2.22967245489289	0.572175568297329	0.623042897330431	0.554372583676404	0.310048290518789	NA	NA	0.653477735007164	0.250595219712362	74.064254326835
a3972	gain_cnaOV49	292	Masitinib	KIT	3	29	2.99573227355399	NA	3.55844473256639	4.06059721566971	-0.502152483103329	1.18661329997815	1.03734392878806	0.479172837250736	0.42318123613866	0.484075212827438	0.310097379204505	NA	NA	0.100838335221013	0.544401713372697	74.064254326835
a3973	SMAD4_mut	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.5523368589811	3.4308706249039	1.1214662340772	0.727894321677947	1.73918939723609	0.663983159969391	1.54069924806116	0.644821222955609	0.310152122152507	NA	NA	0.69504076457676	0.0889174825903767	74.064254326835
a3974	loss_cnaOV84	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	0.665659522756724	-0.0766301196094971	0.742289642366221	1.41987048786933	1.26550962181531	0.569469615013136	0.5227868659205	0.586553930187779	0.310265137550954	NA	NA	0.867064923603248	0.33941152878999	74.064254326835
a3975	loss_cnaOV56	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.166040279866	2.9309917915147	-0.764951511648694	0.365349068841255	1.14050161584302	0.69172545595563	2.09375519711826	0.670714974027692	0.310282806615274	NA	NA	0.385288023477833	0.035427939065571	74.064254326835
a3976	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	293	MP470	PDGFR	5	27	2.99573227355399	NA	4.73102253856113	3.92298720698309	0.80803533157804	1.19709398715046	1.82625115374597	0.460303405773857	0.674997402251991	0.442455754193837	0.310453696258551	NA	NA	0.618135661826703	0.242744844973924	74.0864074561825
a3977	loss_cnaOV35	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	0.636210660851486	1.4441476948479	-0.807937033996409	1.3665819767952	1.3306143604995	0.60547742680677	0.591210075732975	0.607190977326534	0.310556421985614	NA	NA	0.576268993594672	0.331877033221688	74.092286955766
a3978	loss_cnaOV20	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-1.06857898331399	-0.777932278171033	-0.290646705142957	0.818822560111451	0.805816950519605	0.360080227898601	0.354956884802241	0.360685767351435	0.310771542252116	NA	NA	0.0753746709252963	0.543832054863758	74.1190742540301
a3979	loss_cnaOV35	1019	Bosutinib	SRC, ABL, TEC	5	26	0.693147180559945	NA	2.59847813217996	1.55522962086755	1.04324851131241	1.12255681996823	1.62237847052208	0.667478498773249	0.929350294573007	0.643036461755249	0.31084205960726	NA	NA	0.0389893998093471	0.11895391726915	74.1190742540301
a3980	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.866368202767011	0.176616194246604	0.689752008520407	1.05063563190773	1.12917436231231	0.616207613667214	0.656509247899737	0.610846324130086	0.310903049472836	NA	NA	0.142440694578467	0.231522782828682	74.1190742540301
a3981	gain_cnaOV49	305	TPCA-1	IKK	3	29	2.99573227355399	NA	4.02158795400181	3.25315436220263	0.768433591799183	0.949203950295798	1.23594576945138	0.630416503341807	0.809555829977023	0.621737304979231	0.311085072785628	NA	NA	0.993536674154107	0.293596194270513	74.1310437646096
a3982	SMARCA4_mut	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.27076746086922	0.259202440729418	1.0115650201398	1.13783446055589	1.69360798725802	0.6089147407471	0.889026528204814	0.597284039606794	0.311109515213789	NA	NA	0.835263173091944	0.258893130372789	74.1310437646096
a3983	loss_cnaOV40	1058	GDC0941	PI3K (class 1)	8	25	1.38629436111989	0.693147180559945	1.38706857009082	0.670047897724522	0.717020672366301	0.900049135117714	1.41801582034184	0.543627040303015	0.796646143404742	0.505650686036386	0.311245580304485	NA	NA	0.158753337905316	0.108873934535772	74.1358608701725
a3984	SMAD4_mut	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.93849326357051	2.40848417067996	0.530009092890544	1.15182595272887	0.685490817300357	0.701584578359042	0.460146857808563	0.773181900492642	0.311512652739821	NA	NA	0.744031125584455	0.512404008059355	74.1358608701725
a3985	loss_cnaOV57_(ZNRF3)	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.74436757159243	4.21130777268676	0.533059798905669	1.30531744614854	0.824817841892027	0.602538133046801	0.408375602791881	0.646275785793986	0.311568865130139	NA	NA	0.516728467340164	0.479393005041319	74.1358608701725
a3986	loss_cnaOV56	1028	VX-702	p38	3	28	0.693147180559945	NA	3.89311160397879	3.26631110924043	0.626800494738361	0.905510889174225	0.914290195321153	0.686011945966478	0.692206468450057	0.685559681101241	0.311696553242696	NA	NA	0.513069551243881	0.353665293339637	74.1358608701725
a3987	loss_cnaOV1	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.39628759329634	4.89180059460339	0.50448699869295	0.322077174288018	0.835110278706972	0.621400846181426	1.56635439878087	0.604096263159475	0.311845772554053	NA	NA	0.945369660130299	0.0856323953899421	74.1358608701725
a3988	loss_cnaOV41	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.25889019322794	3.71619100213494	0.542699191092998	1.0636312624792	1.01262100681854	0.532282507749743	0.510232455774221	0.53593514991167	0.311915290386376	NA	NA	0.71404513497254	0.335760131900516	74.1358608701725
a3989	NF1_mut	262	VX-11e	ERK	4	28	1.63315443905142	NA	3.45565621076266	2.77408064108834	0.681575569674322	0.85424686338308	1.12979098940134	0.616625241090924	0.797867219523726	0.603275805939539	0.311943048879981	NA	NA	0.385345937017514	0.21698439381048	74.1358608701725
a3990	TP53_mut	260	NG-25	MAP3K7 (TAK1)	22	10	2.32630161961136	NA	2.88517771560128	3.29095057242209	-0.405772856820807	1.16231430052706	0.829613512675921	0.378030328284214	0.34910768682516	0.489110713146396	0.312036585824764	NA	NA	0.429255687770238	0.271951158083535	74.1358608701725
a3991	loss_cnaOV81_(RB1)	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	2.16717646486185	1.44997568859777	0.717200776264087	0.995087266815966	1.0356084782163	0.69619198786553	0.72074158737751	0.692540464229656	0.312167913503478	NA	NA	0.279452561519421	0.255272845996178	74.1358608701725
a3992	loss_cnaOV58	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	1.95894371376246	1.55068358528924	0.408260128473224	1.03336577257427	0.597463914287114	0.607420100053021	0.395078044298087	0.683321818624568	0.312224460190895	NA	NA	0.203952646692772	0.434483824449627	74.1358608701725
a3993	loss_cnaOV55	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	0	NA	-2.77134264862227	-1.73971001065382	-1.03163263796845	2.47110572833752	1.83773798911385	0.516234291083284	0.417478145972529	0.561360021983273	0.312319383197244	NA	NA	0.273057214418487	0.302956952975237	74.1358608701725
a3994	loss_cnaOV52, loss_cnaOV53	333	T0901317	LXR	8	24	2.32630161961136	NA	5.25734180549889	4.58535506671265	0.671986738786236	0.4586352238584	1.21664005965025	0.617591362487998	1.46518780902381	0.552329946277962	0.312368168441729	NA	NA	0.00467930381997564	0.0310343472324338	74.1358608701725
a3995	PIK3CA_mut	207	AS601245	JNK 	5	13	2.07944154167984	NA	1.83061171940359	2.05610856515566	-0.225496845752076	1.08187060067679	0.967292580719565	0.226136336167585	0.20843236299333	0.233121653413623	0.312422522237089	NA	NA	0.469493975040287	0.69640659999891	74.1358608701725
a3996	gain_cnaOV95_(MECOM)	1020	Lenalidomide	TNFA	8	23	1.6094379124341	NA	4.65335792549171	4.31177423913192	0.341583686359789	0.724599226643984	0.774710272585527	0.447734378736902	0.471410503626744	0.440917977271405	0.312426761898988	NA	NA	0.0408048658632231	0.279739786994939	74.1358608701725
a3997	loss_cnaOV1	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	4.29208260045351	3.61828312851041	0.673799471943098	1.05183728555189	1.04140671189622	0.646575208445186	0.640592876102089	0.647008958408021	0.312433919992104	NA	NA	0.829050830411415	0.384231260656821	74.1358608701725
a3998	loss_cnaOV39	1019	Bosutinib	SRC, ABL, TEC	10	21	0.693147180559945	NA	2.35990789276249	1.42044199408719	0.9394658986753	1.20998912720386	1.67707951336823	0.607170813635853	0.776425074865169	0.560179700000323	0.312436639484675	NA	NA	0.0390116330179916	0.088709750271695	74.1358608701725
a3999	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	306	TG101348	JAK2	5	27	2.32630161961136	NA	3.45433123762243	2.70734146650704	0.746989771115393	0.988928732720503	1.43101987587868	0.541187135113261	0.755352480315194	0.521998180253594	0.312528669202813	NA	NA	0.623475573377081	0.191833009167796	74.1358608701725
a4000	RB1_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.48001683012858	-0.226112485986512	0.706129316115092	1.26068830931381	1.63047044997346	0.439216780939192	0.560114114566064	0.43308317309681	0.312704278597214	NA	NA	0.0967364347964899	0.442296253213276	74.1358608701725
a4001	loss_cnaOV58	1018	ABT-888	PARP1, PARP2	5	26	1.6094379124341	NA	4.7022169184139	4.22215561756407	0.48006130084983	0.720993378296496	0.797291818373719	0.609828021980732	0.665833161996688	0.602114921772355	0.31270908053138	NA	NA	0.219721715069497	0.228495509556777	74.1358608701725
a4002	loss_cnaOV55	1170	CCT018159	HSP90	8	25	2.30258509299405	NA	4.18035950301458	3.53963100454293	0.640728498471646	1.19903788194651	1.20190985437413	0.533379502552808	0.534368853660811	0.533091975358909	0.312728615700591	NA	NA	0.193325230832333	0.213431386098843	74.1358608701725
a4003	gain_cnaOV94	1259	BMN-673	PARP1	7	26	2.30258509299405	NA	1.67987477617481	1.95977883790802	-0.279904061733209	1.27819370787022	1.41050476348677	0.201968125457498	0.218984071044753	0.198442478876346	0.312788396235158	NA	NA	0.0324431609888016	0.62567496041734	74.1358608701725
a4004	TP53_mut	167	OSU-03012	PDPK1 (PDK1)	12	7	2.77258872223978	NA	2.11036288435366	2.66049619048647	-0.550133306132815	1.48639478668854	0.350925197233069	0.453271364897706	0.370112510525166	1.56766544685431	0.31285589772687	NA	NA	0.379309071418637	0.242361690234558	74.1358608701725
a4005	loss_cnaOV16, loss_cnaOV17	1373	Dabrafenib	BRAF	6	26	2.30258509299405	NA	4.44863560848857	3.46113973309806	0.987495875390513	1.18150541577896	2.13165109458162	0.492562728778464	0.835794624554865	0.46325399025225	0.312926814233591	NA	NA	0.744586987239097	0.144501770486376	74.1358608701725
a4006	loss_cnaOV35	326	GSK690693	AKT	5	27	2.32630161961136	NA	4.89779449509057	4.01380830679765	0.883986188292925	0.702923481938727	1.51342833066371	0.617259708858719	1.2575852294119	0.584095176746991	0.313193030921434	NA	NA	0.0900068193849581	0.0607151509848331	74.1465133659686
a4007	PIK3R1_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	1.88248380210354	1.18015380594461	0.702329996158926	2.20338022538604	2.35074679420217	0.301217668131318	0.318751157002816	0.298768883952596	0.313211608166318	NA	NA	0.358034206899973	0.541824913498991	74.1465133659686
a4008	loss_cnaOV35	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	4.85827674085566	4.42391572468185	0.434361016173808	0.763353919985691	0.675317088971201	0.631971928064525	0.56901655287491	0.643195653223476	0.313246354716808	NA	NA	0.0782777638138403	0.285052587614406	74.1465133659686
a4009	SMARCA4_mut	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.70386202222069	2.94040791037197	0.763454111848723	1.21205544424921	1.05515670628413	0.715960788823928	0.629883818822855	0.72354571344888	0.313284359376311	NA	NA	0.429297776977125	0.390235184566939	74.1465133659686
a4010	loss_cnaOV84	193	GW-2580	CSF1R (cFMS)	6	26	2.99573227355399	NA	5.99907974469086	5.66356541940483	0.335514325286024	0.685461620107307	0.574198011393495	0.564657800068116	0.489472080484244	0.584318159639354	0.313877251142537	NA	NA	0.187427055021841	0.304245751836301	74.1975453616172
a4011	loss_cnaOV57_(ZNRF3)	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.48454452080904	5.75388526322772	0.730659257581312	0.440385933006667	1.31805464153707	0.571529221057134	1.65913396141618	0.554346712613705	0.313933103706924	NA	NA	0.566560790607914	0.0772079025373631	74.1975453616172
a4012	SMARCA4_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	0.990452370219962	1.81252206334107	-0.822069693121112	1.37091473028907	1.7175558574445	0.484331209086844	0.599650492447309	0.478627632142483	0.314028482600079	NA	NA	0.224260512577322	0.413276796950182	74.1975453616172
a4013	loss_cnaOV35	263	FR-180204	ERK	5	27	2.99573227355399	NA	5.10853469600887	4.75680792899294	0.351726767015935	0.710561581478507	0.746465317735552	0.474166796674485	0.494998288936584	0.471189697175642	0.31412090107072	NA	NA	0.762594953284279	0.353618548906514	74.1975453616172
a4014	loss_cnaOV40	290	KIN001-260	IKK	7	24	2.99573227355399	NA	4.57603632153941	4.93022436692963	-0.354188045390217	1.43641377137881	0.689397746761059	0.395051192765337	0.246578007289802	0.513764437226941	0.314275997658663	NA	NA	0.661635221742317	0.548261715909294	74.1975453616172
a4015	gain_cnaOV50	263	FR-180204	ERK	4	28	2.99573227355399	NA	5.15270473029171	4.76305959434596	0.389645135945758	0.496714215372245	0.76394239154725	0.525435761406719	0.784445308563903	0.510045181753287	0.314357203420289	NA	NA	0.762598941629671	0.229876076530848	74.1975453616172
a4016	gain_cnaOV19	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	2.83764290836867	1.44717367960595	1.39046922876272	1.20145661009251	2.39930034835067	0.606895987934026	1.15731955451613	0.579531124445742	0.314370553098659	NA	NA	0.605876600028993	0.182927976025279	74.1975453616172
a4017	loss_cnaOV83	1004	Vinblastine	Microtubules	5	26	-2.30258509299405	NA	-2.37407788046857	-3.49617076780182	1.12209288733326	1.96165455947421	1.75869745148396	0.627547080610413	0.572013498459187	0.638024969210283	0.314510067131835	NA	NA	0.134995211624475	0.284367673071284	74.1975453616172
a4018	loss_cnaOV81_(RB1)	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	4.04940297259532	4.4857230283462	-0.436320055750885	0.21800135896873	0.764822850372567	0.598648122597777	2.00145566896888	0.570485120231882	0.314655729614095	NA	NA	0.519649091377173	0.0275603296458836	74.1975453616172
a4019	loss_cnaOV1	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.48158102705471	3.61629693521753	0.865284091837182	1.19805795627279	1.207867555307	0.716747442387469	0.722238926177761	0.716373320928596	0.314672448102295	NA	NA	0.193385048247747	0.336823454514235	74.1975453616172
a4020	loss_cnaOV56	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.83203686892792	1.80724208706828	1.02479478185963	1.07270155424316	1.37473869408272	0.755034415760726	0.955340073672844	0.745446961135707	0.314928460099896	NA	NA	0.0324675732263822	0.232230376943953	74.1975453616172
a4021	loss_cnaOV58	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	0.60685155219086	1.32484648327053	-0.717994931079669	1.40383174369433	1.19059455115115	0.588421674933578	0.511453694009077	0.60305578451158	0.314948290808921	NA	NA	0.261810786662256	0.330101139851458	74.1975453616172
a4022	loss_cnaOV85	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	8.17246345462844	8.92814677149953	-0.755683316871089	1.59951243219074	1.71560227916244	0.446558738204013	0.472446041470328	0.440476983534911	0.314953866433785	NA	NA	0.920869944186802	0.303873148818291	74.1975453616172
a4023	loss_cnaOV52, loss_cnaOV53	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	9	24	-2.30258509299405	NA	0.0502191088901097	-0.476111313380515	0.526330422270624	1.30159165058249	1.42993549442521	0.376503492983112	0.404374461095443	0.368079835994416	0.315057150221139	NA	NA	0.887755513529587	0.329362060297575	74.1975453616172
a4024	loss_cnaOV38	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	8	24	2.32630161961136	NA	5.40032518397346	5.05647710817624	0.343848075797215	0.797464286943799	0.48179941189972	0.601895992374083	0.431176770454484	0.713674751991566	0.315188435524412	NA	NA	0.0110469679837743	0.279955428341451	74.1975453616172
a4025	gain_cnaOV49	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.46556156577853	2.74194700094419	-0.276385435165664	0.290146851872099	0.582873370133018	0.48653354084249	0.952570856386538	0.474177496053027	0.315268748347086	NA	NA	0.131364683201319	0.238586768612689	74.1975453616172
a4026	NF1_mut	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.01451199102918	4.59914040890552	-0.584628417876336	1.49085540289201	0.904280761342036	0.598656369757781	0.392142938035611	0.646512060047251	0.315309336791414	NA	NA	0.320293270663697	0.495056394278053	74.1975453616172
a4027	PIK3CA_mut	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.59715983770763	3.93571511481631	-0.338555277108684	1.73788740638186	1.4912741314942	0.223249271142481	0.194808522039715	0.227024173462637	0.315332089605855	NA	NA	0.0654566512734116	0.774000096147943	74.1975453616172
a4028	SMAD4_mut	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.71265087059108	-2.25373136521918	-0.4589195053719	1.31524650399895	0.631617992388086	0.615723980193196	0.348922809508768	0.726577632212107	0.315611326380961	NA	NA	0.667850783455525	0.609727293454226	74.1975453616172
a4029	loss_cnaOV16, loss_cnaOV17	281	CH5424802	ALK	6	26	1.63315443905142	NA	3.65892371296994	3.98960918063556	-0.330685467665622	0.95290053909035	0.668178906031619	0.457091101480501	0.347030413039013	0.494905577953061	0.315934317261347	NA	NA	0.955286911728743	0.450351121203941	74.1975453616172
a4030	loss_cnaOV70	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.92973254139999	4.36182855270185	0.567903988698138	0.225701855865091	0.974110898767822	0.602305789331587	2.51616889245958	0.582997263880832	0.316030889002699	NA	NA	0.78409343550776	0.0237069785205783	74.1975453616172
a4031	loss_cnaOV1	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.05510296742831	4.3587388379106	-0.303635870482287	0.324822430816497	0.599860593351375	0.518983961481193	0.934774946788762	0.506177391626772	0.316044445223252	NA	NA	0.248609913989469	0.243678951014107	74.1975453616172
a4032	loss_cnaOV36	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	1.93638052362634	2.8330847887569	-0.896704265130557	1.4910521246853	1.68436435148304	0.536251123071468	0.601390286955807	0.532369534145643	0.316103456382031	NA	NA	0.31594137710164	0.410814415893642	74.1975453616172
a4033	gain_cnaOV19	164	JQ12	HDAC	3	16	1.63315443905142	NA	2.92003830832061	1.58274082293015	1.33729748539046	3.14338299804615	2.02203920610919	0.612301352960976	0.425432563013062	0.661360809103048	0.316387285318281	NA	NA	0.653753999221443	0.542376533705093	74.1975453616172
a4034	loss_cnaOV56	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.22540769477065	4.51778386144591	-0.292376166675263	0.828440548421821	0.663734851341878	0.432264389607404	0.352923534745178	0.440501453380313	0.316462482980869	NA	NA	0.0508525768848261	0.60761762886109	74.1975453616172
a4035	loss_cnaOV85	312	AV-951	VEGFR	7	25	-2.05572501506252	NA	0.925144104351707	0.559963969342212	0.365180135009495	0.680773627794998	0.581267461372725	0.606123314526751	0.536419332506021	0.628248025697299	0.316518172277302	NA	NA	0.0140952946340252	0.229509353487747	74.1975453616172
a4036	loss_cnaOV40	1377	Afatinib (rescreen)	ERBB2, EGFR	8	25	2.30258509299405	NA	3.11537136457537	2.50782624986356	0.607545114711812	1.48212186186198	1.75316047056327	0.358275356442004	0.409915763571935	0.346542786534887	0.316551508141843	NA	NA	0.636401486071317	0.35175986682765	74.1975453616172
a4037	loss_cnaOV55	255	CP724714	ERBB2	7	25	2.32630161961136	NA	4.71646112089844	4.33067991225058	0.385781208647852	1.06122705646281	0.912336326351414	0.408668682873918	0.363523721241809	0.422849773164963	0.316551939273289	NA	NA	0.784101410957966	0.404981150716289	74.1975453616172
a4038	gain_cnaOV49	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	2.64622522379914	3.1100196993267	-0.463794475527566	0.87571145415478	0.918602932332813	0.506383143218542	0.529620200040904	0.504891133266632	0.3166294043014	NA	NA	0.233900147569585	0.460457294163912	74.1975453616172
a4039	gain_cnaOV48_(SOX17)	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.17433925677401	2.93013327666214	-0.755794019888132	1.83394003153107	1.03508074051159	0.683092192350039	0.412114903919271	0.730178806645148	0.316840566598598	NA	NA	0.385514449049238	0.551203462447876	74.1975453616172
a4040	loss_cnaOV70	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-5.47642160439736	-4.00390608174346	-1.4725155226539	0.481642355396725	2.40634316542095	0.634054380486428	3.0572799633475	0.611930810124627	0.316870774988472	NA	NA	0.927171611927203	0.013915785222354	74.1975453616172
a4041	loss_cnaOV83	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.8753580456699	3.41150916288226	0.463848882787643	1.16237386444758	0.849701695466701	0.517574466956036	0.399053090382488	0.545896148333413	0.316966770633186	NA	NA	0.79202517378104	0.434423151904839	74.1975453616172
a4042	gain_cnaOV50	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	1.3357305921261	2.14278471247686	-0.807054120350766	1.94002843036642	1.99003649269614	0.406557462667589	0.416001182105531	0.405547397403428	0.317060987301003	NA	NA	0.12829916350076	0.481626022146237	74.1975453616172
a4043	PIK3R1_mut	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.94662879925801	2.75964382462438	0.186984974633632	1.47846163369588	1.19541799767916	0.151171646119716	0.126472659399489	0.156418068823335	0.317119049658069	NA	NA	0.0912913213374035	0.800029969143341	74.1975453616172
a4044	loss_cnaOV52, loss_cnaOV53	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	8	24	2.30258509299405	NA	1.2671299637986	0.736626879457	0.530503084341599	1.04639630684237	1.28568928450102	0.429901179253979	0.506981036604055	0.412621533629323	0.317228277872891	NA	NA	0.843169369133765	0.260807456128375	74.1975453616172
a4045	BRCA1_mut	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.52247940483526	0.8335716359912	0.68890776884406	0.726068589129539	1.30697613701276	0.547779691355242	0.948819132459606	0.527100495054664	0.317333313216704	NA	NA	0.956958401468867	0.168003134406186	74.1975453616172
a4046	gain_cnaOV51_(MYC)	1059	AZD8055	MTORC1/2	8	25	0.693147180559945	NA	0.740288777364358	0.134191369353004	0.606097408011355	1.50343864599506	0.974913732428573	0.542928464109149	0.40314076641964	0.621693374347622	0.317477418822264	NA	NA	0.142620305497714	0.312370713676663	74.1975453616172
a4047	loss_cnaOV35	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	2.94137438298706	2.3524492798783	0.588925103108762	1.16091459094256	0.7770239119356	0.708320458550569	0.507294083219859	0.757924040769509	0.317560999673302	NA	NA	0.614694760738932	0.475944905213058	74.1975453616172
a4048	loss_cnaOV85	226	GSK1070916	AURKB	7	25	0.940007258491471	2.32630161961136	2.77555480199414	2.18472610374605	0.590828698248091	0.63676156931486	1.57149866774337	0.411972013001425	0.927864881801531	0.375965128304247	0.317578495019624	NA	NA	0.818966964259233	0.147871297266516	74.1975453616172
a4049	loss_cnaOV38	192	LFM-A13	BTK	4	15	2.77258872223978	NA	5.04318774983576	4.64025793352197	0.402929816313792	0.604278766447147	0.692814902527373	0.59426418617822	0.666794596611122	0.58158364498788	0.317688559832061	NA	NA	0.956014410892691	0.300029310508143	74.1975453616172
a4050	loss_cnaOV82	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-3.34265502982912	-4.27042292536983	0.927767895540707	3.56498292081411	0.981080015535772	0.702205178587227	0.260244695738638	0.945659763576011	0.317887946378612	NA	NA	0.212746937595816	0.696791995520238	74.1975453616172
a4051	loss_cnaOV83	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	2.8646023656436	2.33366014429597	0.530942221347621	0.941110854857313	0.805377842615847	0.638963171280669	0.564165441942671	0.659246124307485	0.318097026012841	NA	NA	0.614719766272103	0.357143981537713	74.1975453616172
a4052	gain_cnaOV72_(ASXL1)	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	3.23293513549101	2.90716062430438	0.325774511186627	0.339544482327017	0.635204892730674	0.548604171026771	0.959445752008633	0.512865242246733	0.318101366800643	NA	NA	0.846451292043958	0.199335889648233	74.1975453616172
a4053	loss_cnaOV83	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.93012228560529	3.48624245325316	0.443879832352128	1.3838414836317	0.868402524122857	0.465591718476091	0.320759160353559	0.511145258128396	0.318171804019268	NA	NA	0.725558504485008	0.522040937716322	74.1975453616172
a4054	loss_cnaOV21, loss_cnaOV22	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-1.69983680706739	-2.8389773962543	1.13914058918691	2.24533842058093	1.70914507886156	0.650933786625501	0.507335811272578	0.666497305158953	0.318183356317291	NA	NA	0.693049046334743	0.474638653070719	74.1975453616172
a4055	gain_cnaOV19	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.21303025078932	4.77025506243054	0.442775188358775	1.39602409520426	0.670772341797467	0.597111020104134	0.317168729307635	0.660097563313763	0.318208441577483	NA	NA	0.76266338674921	0.639392224492323	74.1975453616172
a4056	loss_cnaOV57_(ZNRF3)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.25643831302282	2.73461491284383	0.521823400178999	1.30432033216349	0.908445051473243	0.547006158112912	0.400073039813346	0.574413828698552	0.31826163311427	NA	NA	0.965828601486422	0.48867828410088	74.1975453616172
a4057	gain_cnaOV96	281	CH5424802	ALK	5	27	1.63315443905142	NA	4.23298282144061	3.87105432841263	0.361928493027982	0.605041597539744	0.739486409740585	0.500588266713454	0.598187784938552	0.489432244136776	0.31829390784245	NA	NA	0.955294556445296	0.278307068964007	74.1975453616172
a4058	PTEN_mut	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	3.90851146829572	4.46094032251044	-0.552428854214724	0.1219862197971	0.635887272972584	0.89806501303872	4.52861688093605	0.868752808390524	0.318389127681712	NA	NA	0.265929910275943	0.000764840099692862	74.1975453616172
a4059	loss_cnaOV85	1052	RO-3306	CDK1	7	26	1.6094379124341	NA	3.80216117448695	3.39553532952478	0.406625844962175	0.96362106585935	0.879266753609941	0.453715501670207	0.421976915375495	0.46246016159797	0.318419136003572	NA	NA	0.792045783103912	0.33963430123794	74.1975453616172
a4060	PIK3CA_mut	1061	SB590885	BRAF	7	26	1.6094379124341	NA	3.73081038803521	3.98050544170033	-0.249695053665116	1.04837603697719	1.34111998868294	0.193613623692578	0.238173179143878	0.186183977401106	0.318443134530027	NA	NA	0.569029861028447	0.609216308884255	74.1975453616172
a4061	ARID1A_mut	295	NVP-BHG712	EPHB4	8	24	2.32630161961136	NA	3.89850443037045	3.03533820086253	0.863166229507923	0.577803048181747	1.12716819487026	0.841580455673405	1.49387621305247	0.765782989119271	0.318696846942008	NA	NA	0.0596799283546714	0.00976538788712575	74.1975453616172
a4062	loss_cnaOV39	208	SB-715992	KIF11	9	23	-2.05572501506252	NA	-1.59123112534028	-1.21024737536498	-0.380983749975299	2.28073658089298	1.70964898307757	0.202760085837631	0.167044170364529	0.222843258321649	0.318708687741845	NA	NA	0.0711276342281512	0.658326814405283	74.1975453616172
a4063	gain_cnaOV94	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	2.88595533329485	3.57277862575373	-0.686823292458877	0.663549802286012	1.14027443720938	0.627227289697028	1.03507421762871	0.602331570406642	0.318725765003371	NA	NA	0.768475426325518	0.214239460530565	74.1975453616172
a4064	loss_cnaOV85	333	T0901317	LXR	7	25	2.32630161961136	NA	5.28189838266856	4.6053586946566	0.676539688011967	0.78470974708373	1.15522409455972	0.619977667683706	0.862152777541298	0.5856350219823	0.318817409322719	NA	NA	0.00469631065465209	0.0932434808264387	74.1975453616172
a4065	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	277	ABT-869	VEGFR and PDGFR family	7	25	0.0237165266173161	NA	2.89483546625988	2.66597197843592	0.228863487823962	0.632583852613476	0.547775504893264	0.404527462450322	0.361791542541639	0.41780526105956	0.318923413323392	NA	NA	0.131463005931055	0.407586371499192	74.1975453616172
a4066	loss_cnaOV54	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	6	17	2.30258509299405	NA	4.1595121373171	3.74561889459983	0.413893242717264	0.890435293032699	0.867517815563779	0.474088807784122	0.464821246367719	0.477100568186354	0.319006616969999	NA	NA	0.938881790350975	0.351301071716333	74.1975453616172
a4067	loss_cnaOV85	225	Genentech Cpd 10	AURKA, AURKB	7	25	2.32630161961136	NA	3.57337961700935	2.63996891722541	0.933410699783935	1.43769578647165	1.90993075435617	0.51137829711226	0.649240756331828	0.488714419439037	0.319022319534724	NA	NA	0.341067036183593	0.184071604591296	74.1975453616172
a4068	loss_cnaOV20	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.03094468222964	4.46295461506562	-0.432009932835983	1.06209780934822	0.817140569141666	0.506630959850971	0.406751552478104	0.528684964558511	0.319194725490452	NA	NA	0.868132591709499	0.427507453550118	74.1975453616172
a4069	loss_cnaOV39	290	KIN001-260	IKK	9	22	2.99573227355399	NA	4.6278695124035	4.94121879297525	-0.31334928057175	1.24605122418614	0.721851769141544	0.349106267392022	0.251473835496944	0.434090895066169	0.31921761013863	NA	NA	0.661752862114826	0.495038898506347	74.1975453616172
a4070	loss_cnaOV38	1007	Docetaxel	Microtubules	8	23	-4.38202663467388	NA	-4.06953003995266	-4.84998192305066	0.780451883097995	1.8372385024721	1.21194500871229	0.561922369147912	0.424796172107135	0.643966415544906	0.319291488068989	NA	NA	0.131166791327563	0.291164510895314	74.1975453616172
a4071	loss_cnaOV42	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.56583076022423	2.90660359407646	0.659227166147766	1.04220635425661	0.983974005360782	0.666048070614124	0.632530365464894	0.669964005711772	0.319381321766798	NA	NA	0.084522281611755	0.302106460372587	74.1975453616172
a4072	gain_cnaOV49	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	0.686769619457712	1.48640946857411	-0.799639849116402	0.535379309261618	1.50508360581239	0.548056240277225	1.49359498076092	0.531292644493849	0.319450784477414	NA	NA	0.471431431487878	0.102048796523964	74.1975453616172
a4073	loss_cnaOV70	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-4.4662190770173	-3.60812670904442	-0.858092367972879	2.14326761920092	1.68852856056906	0.497806852797649	0.400366412614774	0.50818943073352	0.31963199923069	NA	NA	0.239928175485777	0.563682912585108	74.1975453616172
a4074	gain_cnaOV4_(KRAS)	326	GSK690693	AKT	8	24	2.32630161961136	NA	4.58581281286115	4.00730392733751	0.57850888552364	1.45976643000444	1.44313527774514	0.399789703971774	0.396302362921089	0.400869478035037	0.319646478144759	NA	NA	0.0901504593071108	0.349648767102198	74.1975453616172
a4075	gain_cnaOV96	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-0.118365580077201	-0.689648487526544	0.571282907449343	1.05594998592663	2.00567892342082	0.304944707924929	0.541013225117878	0.284832682229607	0.319672604586451	NA	NA	0.0390469747462194	0.458361055674285	74.1975453616172
a4076	MLL2_mut	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.43650615034528	4.44258915969548	-0.00608300935019468	1.10825712391287	1.01130989153661	0.00597637149906839	0.00548880690134223	0.00601498057232687	0.319674501613457	NA	NA	0.369905465782425	0.993430879546168	74.1975453616172
a4077	gain_cnaOV96	341	EX-527	SIRT1	4	27	2.99573227355399	NA	5.58180208563592	5.80168527048298	-0.219883184847061	0.982179866767709	0.493765834283866	0.389691273563825	0.223872624848931	0.445318751480585	0.319791860388869	NA	NA	0.106806963192746	0.688012108583248	74.1975453616172
a4078	TP53_mut	1199	Tamoxifen	ER	22	10	1.6094379124341	NA	4.06512166729974	3.7922373182213	0.272884349078439	0.788785536713914	0.675639040854416	0.360662212007794	0.34595506177164	0.403890735404141	0.319824970468172	NA	NA	0.521034904295874	0.327392801447446	74.1975453616172
a4079	gain_cnaOV94	1008	Methotrexate	Dihydrofolate reductase (DHFR)	7	24	-1.6094379124341	NA	1.03811421091221	0.427920471200733	0.610193739711476	0.610004061380156	1.30390172617546	0.511094173665531	1.00031094601385	0.467975252629864	0.319888204889974	NA	NA	0.425707148855869	0.096924927890031	74.1975453616172
a4080	gain_cnaOV19	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	4.01882831613517	3.4952910544137	0.523537261721467	0.247341991590435	0.927032475875989	0.583086380898144	2.11665337678842	0.564745330228865	0.319896559524343	NA	NA	0.659790786921129	0.0402421562392594	74.1975453616172
a4081	MLL2_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.13862320771968	2.76379053671344	0.374832671006236	0.938785332140494	0.965307532493317	0.388984530477461	0.399274102580611	0.388303891132053	0.320026491238665	NA	NA	0.965832790050041	0.567340586851208	74.1975453616172
a4082	loss_cnaOV20	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-2.64131903929041	-2.2421585532079	-0.399160486082511	1.21431367161412	0.60054193056761	0.534728387843219	0.328712832123456	0.664667137738808	0.32006654551232	NA	NA	0.668034556460596	0.564453185186934	74.1975453616172
a4083	loss_cnaOV20	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.74942750605075	3.7109511465919	1.03847635945885	1.30192232448781	1.4896879211784	0.709177527086206	0.797648477122012	0.697110008542843	0.320111653585216	NA	NA	0.0655817305882088	0.218993426122071	74.1975453616172
a4084	gain_cnaOV50	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	-0.114568322091923	0.335702335900264	-0.450270657992187	1.25164142877123	1.12515319562694	0.395665426440952	0.359744130900356	0.400186089985102	0.320219741399299	NA	NA	0.142693820243968	0.535255506765472	74.1975453616172
a4085	RB1_mut	1262	UNC1215	LMBL3	3	30	0	NA	2.44783408973221	2.81367056602026	-0.365836476288044	0.380702431850741	0.493337531318258	0.751423758989686	0.96095124612042	0.741554114706182	0.320288856973407	NA	NA	0.106128436978269	0.230132884988416	74.1975453616172
a4086	loss_cnaOV54	151	QS11	ARFGAP	6	13	2.32630161961136	NA	3.53154737010773	3.87534814072666	-0.343800770618937	1.11314356965338	1.5936890709985	0.234074791576154	0.308855730735608	0.215726377795598	0.320302303765882	NA	NA	0.0598845358430046	0.596253356167062	74.1975453616172
a4087	gain_cnaOV94	275	I-BET	BRD2, BRD3, BRD4	6	25	2.99573227355399	NA	4.33355430310091	3.82057030528939	0.512983997811523	0.569090944216968	1.3086837570602	0.4226413185505	0.901409525181174	0.391984690758202	0.320348144848011	NA	NA	0.695488122936617	0.158834256493897	74.1975453616172
a4088	loss_cnaOV36	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.11245889954084	4.43984231238164	-0.327383412840797	0.509226855922481	0.637274249092667	0.520028861373963	0.64290288116822	0.513724528029991	0.32047795359317	NA	NA	0.266000134077894	0.385244424922556	74.1975453616172
a4089	loss_cnaOV84	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	2.36420152687201	1.680924765746	0.683276761126008	1.49822161297103	1.70380308946047	0.412177081327558	0.456058539811775	0.401030356942466	0.320540298315555	NA	NA	0.336393910807423	0.423422423656556	74.1975453616172
a4090	loss_cnaOV41	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.56367329503676	3.99519792020524	0.568475374831523	1.38025677529756	1.06141053259263	0.512494801039953	0.411862042632587	0.535584825451983	0.320544023750458	NA	NA	0.817681099707293	0.422600733477844	74.1975453616172
a4091	gain_cnaOV19	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.53715147628548	2.56690575781118	0.9702457184743	0.886365164106366	1.73444689541009	0.573226635649482	1.09463430848222	0.559397765963251	0.320647481903766	NA	NA	0.636497355531797	0.186183255081227	74.1975453616172
a4092	loss_cnaOV81_(RB1)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-1.56716612681552	-2.2003220182159	0.633155891400387	1.04529994333386	1.30943536852717	0.492250761778379	0.605716947980509	0.48353351881166	0.320744602353319	NA	NA	0.603748169047816	0.328270566635995	74.1975453616172
a4093	gain_cnaOV95_(MECOM)	1061	SB590885	BRAF	8	25	1.6094379124341	NA	4.31740065547946	3.80278435826477	0.51461629721469	1.37142487806545	1.2438650748797	0.404005313037687	0.375242060608245	0.413723568261182	0.320768233550724	NA	NA	0.569091835283867	0.36538417019904	74.1975453616172
a4094	loss_cnaOV52, loss_cnaOV53	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	4.54604537402301	5.20521932435233	-0.659173950329314	1.57600965612708	1.0004822708853	0.567354199074321	0.41825502005437	0.658856203164925	0.32077542687642	NA	NA	0.796800189191516	0.420419117472302	74.1975453616172
a4095	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	1.01398359620879	0.20783812213712	0.806145474071668	1.51140383327626	1.09100694122908	0.71792088948074	0.533375300712444	0.738900408061106	0.320814447448028	NA	NA	0.142709655839678	0.454825952176385	74.1975453616172
a4096	SMAD4_mut	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.722865681607962	0.2201941974589	0.502671484149062	1.45113560453143	1.09632597826749	0.44268029301701	0.346398698081268	0.458505493907414	0.320838872635688	NA	NA	0.142710305414191	0.546247377559704	74.1975453616172
a4097	RB1_mut	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.88576978564955	4.34867144253456	0.537098343114982	0.817515359606448	0.855186510453993	0.629801073862194	0.65698868749517	0.628048193638897	0.320864040062468	NA	NA	0.868147688040885	0.374408969803431	74.1975453616172
a4098	loss_cnaOV59	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.71556168943657	1.78796987796848	0.927591811468091	1.21193005497442	1.36985408006878	0.684379922737624	0.765383949065993	0.67714643841592	0.321081362507507	NA	NA	0.0325366368097981	0.228709972024616	74.1975453616172
a4099	PIK3CA_mut	328	SNX-2112	HSP90	6	26	0.940007258491471	NA	-0.0616717268612466	0.871030789255955	-0.932702516117202	1.59294108398342	2.4157909926774	0.405665416836401	0.585522293005853	0.386085766088355	0.321104129656994	NA	NA	0.945245043335937	0.270715216555814	74.1975453616172
a4100	PIK3CA_mut	308	XL-880	MET	6	26	1.63315443905142	NA	0.131192687076538	0.281230488469634	-0.150037801393096	0.451653243194672	1.05133895402046	0.153524551198759	0.332196887000823	0.14271115972573	0.321138011520185	NA	NA	0.363129076138935	0.593737389949736	74.1975453616172
a4101	KRAS_mut	328	SNX-2112	HSP90	7	25	0.940007258491471	NA	-0.0765816982422825	0.912513681887333	-0.989095380129616	1.81523398893463	2.39538453803964	0.431705043724443	0.544885885874207	0.412917159822315	0.321154386047253	NA	NA	0.945245239364655	0.259150766434051	74.1975453616172
a4102	loss_cnaOV84	1016	Temsirolimus	MTOR	6	25	-1.6094379124341	NA	-2.30293439191364	-1.96369960268569	-0.339234789227946	1.25039951305048	1.62610233656809	0.216381480565837	0.271301120711689	0.208618351747717	0.321307667738947	NA	NA	0.0358707219566516	0.588059389180806	74.1975453616172
a4103	loss_cnaOV1	1026	17-AAG	HSP90	3	30	0	NA	-1.41628747151543	-0.442286626967511	-0.974000844547918	2.06845879194531	2.31245248183515	0.423940717166214	0.470882402076719	0.421198209346537	0.321310887282705	NA	NA	0.0587406158273533	0.507293013794892	74.1975453616172
a4104	gain_cnaOV48_(SOX17)	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	0.38198839061754	1.54581902507835	-1.16383063446081	0.968006158462458	1.81542446007247	0.65751097668957	1.20229672537352	0.64107907547657	0.321393479678074	NA	NA	0.610641768207893	0.155329970731013	74.1975453616172
a4105	loss_cnaOV41	308	XL-880	MET	5	27	1.63315443905142	NA	-0.201155973894478	0.337219581190448	-0.538375555084927	0.621397713281763	0.999907654011022	0.561909082882614	0.866394490320258	0.538425276499576	0.3214260998289	NA	NA	0.363138792976693	0.147846954353182	74.1975453616172
a4106	gain_cnaOV4_(KRAS)	329	QL-XI-92	DDR1	8	24	2.32630161961136	NA	4.84108368344158	4.43120467397315	0.409879009468436	1.25547810754785	0.921049531421585	0.406204460098196	0.326472446635486	0.445012993856923	0.321484471186123	NA	NA	0.186674523037195	0.415784418731254	74.1975453616172
a4107	PIK3CA_mut	1031	Elesclomol	HSP70	7	24	-1.6094379124341	NA	-3.59440403914261	-4.19550552236754	0.601101483224926	1.56614203011047	1.5018415557766	0.396670048292953	0.383810326054863	0.400242942348267	0.32150473307504	NA	NA	0.862558227903236	0.389559271736228	74.1975453616172
a4108	loss_cnaOV58	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.5412489872555	3.9157929079942	0.6254560792613	0.658748566220414	1.07856401072724	0.605769360728065	0.949461010366777	0.579897041845087	0.321647608961084	NA	NA	0.101112429341788	0.118107129353688	74.1975453616172
a4109	gain_cnaOV95_(MECOM)	287	KIN001-244	PDPK1 (PDK1)	9	23	2.99573227355399	NA	3.28263404266657	3.64679213662625	-0.364158093959682	0.442303361345785	1.01146952928109	0.406526621868924	0.823322013316081	0.360028733854702	0.3216524252087	NA	NA	0.659830649940538	0.167521191637259	74.1975453616172
a4110	loss_cnaOV42	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	3.8191570221929	2.89422271656727	0.924934305625635	1.05404724608606	1.65526306572234	0.5761731573049	0.877507444813452	0.558783872352039	0.32167364852845	NA	NA	0.660013402621865	0.187250835789215	74.1975453616172
a4111	gain_cnaOV95_(MECOM)	1030	KU-55933	ATM	8	25	2.30258509299405	NA	4.47897659451989	4.04604055284616	0.432936041673734	1.1356248662373	0.984290159891565	0.424269826761543	0.381231562063442	0.439845951240058	0.321685833688205	NA	NA	0.525373596408608	0.354545545999031	74.1975453616172
a4112	gain_cnaOV48_(SOX17)	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.9206368451794	3.23848991780749	0.682146927371907	1.46289772449514	1.06614523652116	0.62179064822172	0.466298440382989	0.639825517204166	0.321826972147015	NA	NA	0.950390232021301	0.506711859493325	74.1975453616172
a4113	gain_cnaOV50	1248	FK866	NAMPT	4	28	0	NA	-2.4952495252782	-1.59594463837431	-0.899304886903894	3.05078045546732	2.72969017789341	0.325424955151099	0.294778631249012	0.329453098445743	0.321914885517106	NA	NA	0.0424498326809138	0.60840631607648	74.1975453616172
a4114	TP53_mut	300	CX-5461	RNA Pol I	21	10	2.32630161961136	NA	3.74871466604904	3.09983800872226	0.648876657326785	1.79696805477008	1.44154785959785	0.38289460921543	0.361095265775221	0.450124949377541	0.321941448547041	NA	NA	0.695297856887599	0.292303076769654	74.1975453616172
a4115	SMAD4_mut	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.96686681715445	1.98409011050556	0.982776706648883	0.563828809633811	1.60154605872562	0.647940483368574	1.74304095473086	0.613642487079575	0.32196835827277	NA	NA	0.946657884006526	0.0869607756864472	74.1975453616172
a4116	loss_cnaOV52, loss_cnaOV53	287	KIN001-244	PDPK1 (PDK1)	8	24	2.99573227355399	NA	3.79082161800914	3.46222302426374	0.328598593745399	0.843288890626557	0.916150366851337	0.36524050667902	0.389663136082882	0.358673210899582	0.322077683040824	NA	NA	0.659840260789178	0.367518993052904	74.1975453616172
a4117	NF1_mut	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.55465692342	4.29597661741117	0.258680306008829	0.564698056459496	0.587908428487132	0.441773198505585	0.458086056875571	0.440001016271348	0.322133901900475	NA	NA	0.248819695665993	0.44267445944619	74.1975453616172
a4118	loss_cnaOV40	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	1.9636081620065	0.967435512294687	0.996172649711812	2.11599807993621	1.3904502717384	0.645409675018841	0.470781452571943	0.716438890307352	0.322292094589202	NA	NA	0.526380712091717	0.426500863766634	74.1975453616172
a4119	gain_cnaOV50	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	0.594461555972815	1.66485135508323	-1.07038979911041	1.13509623067113	1.96650400798354	0.563420133934295	0.942994761314239	0.544311018317218	0.322369044330897	NA	NA	0.780295309544766	0.165669479149644	74.1975453616172
a4120	loss_cnaOV85	292	Masitinib	KIT	7	25	2.99573227355399	NA	4.4612025406298	3.88816942670849	0.57303311392131	0.963716846130313	1.04609800048599	0.556262388596899	0.594607343663499	0.547781482858294	0.322407022910862	NA	NA	0.101130010510401	0.201494995677627	74.1975453616172
a4121	loss_cnaOV54	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	22	-1.38629436111989	0.693147180559945	-2.48039094387055	-1.94516830240669	-0.535222641463867	1.56753233689074	1.11321526798084	0.41894608553178	0.341442807186677	0.480789885710657	0.322439257667123	NA	NA	0.603790178563916	0.327356294465045	74.1975453616172
a4122	loss_cnaOV40	294	MPS-1-IN-1	MPS1	7	24	2.99573227355399	NA	3.96032371156942	4.3782108759544	-0.417887164384984	0.744435195260734	0.821323423853983	0.518459166392262	0.561347941426415	0.508797329100986	0.322485158545329	NA	NA	0.311538005764539	0.229085533546338	74.1975453616172
a4123	loss_cnaOV33_(ZFHX3)	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-3.45883554699957	-4.28696027632907	0.828124729329506	2.92005601557188	0.994958307773866	0.627147600456374	0.283598918963657	0.832321035825476	0.32250847400448	NA	NA	0.212894308999645	0.611861696531354	74.1975453616172
a4124	loss_cnaOV42	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	1.47134113630348	0.783240009719388	0.688101126584089	2.45515052203571	1.01162985412188	0.557421534006886	0.280268407337219	0.680190609026043	0.322606012050453	NA	NA	0.843229014648539	0.61660854535858	74.1975453616172
a4125	loss_cnaOV38	312	AV-951	VEGFR	8	24	-2.05572501506252	NA	0.906709875323883	0.550892873392758	0.355817001931125	0.761939454753332	0.543556646390519	0.591406923524203	0.466988551008054	0.654608869735884	0.322647260782994	NA	NA	0.014133532144174	0.251431892909864	74.1975453616172
a4126	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.56408668256798	-3.62383183188424	1.05974514931626	2.29131008071594	1.65907037541295	0.607171891202788	0.462506213469428	0.638758406527802	0.322672649088218	NA	NA	0.675328817267404	0.512437848656767	74.1975453616172
a4127	loss_cnaOV82	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.94216342771477	3.20729719151045	0.734866236204315	0.922082596079158	1.03333264472672	0.71604064805605	0.796963568479747	0.711161347659406	0.322795845439113	NA	NA	0.0886190328531614	0.299036808676006	74.1975453616172
a4128	loss_cnaOV40	1022	AZD7762	CHEK1, CHEK2	7	24	0.693147180559945	NA	-0.953822046094787	-0.775072213383764	-0.178749832711022	0.76795054435059	0.820310997788157	0.220745402428736	0.232762166816589	0.217904957013857	0.32280566672967	NA	NA	0.0756248586556533	0.604990138172793	74.1975453616172
a4129	PTEN_mut	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	2.53593417987467	3.64691376909388	-1.11097958921921	2.24346056676502	1.6412046056969	0.657522319666709	0.495207986125291	0.67692936356796	0.322887975671132	NA	NA	0.695317952926849	0.483856264133736	74.1984898004706
a4130	loss_cnaOV85	302	PI-103	PI3Ka, PRKDC (DNAPK)	7	25	2.32630161961136	NA	2.19500837299717	1.03646052640168	1.15854784659549	2.00090828623786	2.36127297244542	0.505092542469982	0.579010969450187	0.490645452734615	0.323152972549599	NA	NA	0.358374324901499	0.219996907416944	74.2391514107364
a4131	loss_cnaOV81_(RB1)	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	2.69924238406441	3.30547901015137	-0.606236626086959	1.2460119678379	1.22125418444781	0.495391531292922	0.486541575631018	0.496404953045111	0.32322140772198	NA	NA	0.597007800677699	0.414725977169099	74.2391514107364
a4132	PIK3R1_mut	1053	MK-2206	AKT1, AKT2	5	27	1.38629436111989	0.693147180559945	0.606980807143178	1.4400602408674	-0.833079433724226	1.55180859992272	1.12099930002556	0.701537446399794	0.536844191845383	0.743157853626873	0.323476762711437	NA	NA	0.0941050598846531	0.305541318936397	74.2798215797871
a4133	PIK3CA_mut	333	T0901317	LXR	6	26	2.32630161961136	NA	3.84340498967423	4.96333946565575	-1.11993447598151	1.90385133830827	0.748037075316079	1.08247522781998	0.588246809741284	1.49716439590684	0.323654916756964	NA	NA	0.00470880589604567	0.212187478642168	74.2806450734905
a4134	gain_cnaOV4_(KRAS)	288	KIN001-055	JAK3, MNK1	8	24	2.32630161961136	NA	4.11978654606735	3.69472148563518	0.425065060432163	0.909446937061141	1.05406992203856	0.415851271951035	0.467388522749609	0.403260781419597	0.323749264591974	NA	NA	0.714278536992869	0.290667893145189	74.2806450734905
a4135	loss_cnaOV41	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	6.24123188987421	5.89472075161703	0.346511138257178	0.901948022048153	0.660755705802123	0.497442073754031	0.384180828370039	0.524416414742164	0.323762038217887	NA	NA	0.907750741789296	0.450695324932407	74.2806450734905
a4136	loss_cnaOV34	304	SB52334	ALK5	5	27	2.99573227355399	NA	3.86994393429687	4.45862131749248	-0.588677383195612	1.15750940526218	1.03036089827706	0.561604918676087	0.508572440551595	0.571331253136627	0.323793495408963	NA	NA	0.346724106726826	0.334706871845152	74.2806450734905
a4137	loss_cnaOV16, loss_cnaOV17	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-0.942631415463168	-2.40297079130903	1.46033937584587	3.75581211307813	2.44843961776821	0.553973236671079	0.38882120081588	0.596436753125644	0.323994577870264	NA	NA	0.407802079574343	0.574994834341648	74.3088085449007
a4138	loss_cnaOV35	1016	Temsirolimus	MTOR	5	26	-1.6094379124341	NA	-2.36392374292181	-1.96501837323135	-0.398905369690468	1.22155195240884	1.61492153196877	0.254639845299215	0.326556204919363	0.247012230497761	0.324229677955548	NA	NA	0.0359074790562463	0.547600588750465	74.3447585292673
a4139	gain_cnaOV4_(KRAS)	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.65113145565821	2.28051292997916	0.370618525679051	0.704629432898606	0.898816316909555	0.429215113561623	0.525976503925549	0.412340673735616	0.324486844496288	NA	NA	0.604088926582587	0.271031758854296	74.3794577782285
a4140	loss_cnaOV81_(RB1)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	2.88475490443567	2.20628116102738	0.678473743408282	1.56658620564689	1.38344804765693	0.483414874749259	0.433090589565174	0.490422278275918	0.32462262955411	NA	NA	0.525389933112469	0.461350435765129	74.3794577782285
a4141	SMAD4_mut	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	5.17434082639159	4.75583585768142	0.418504968710168	0.210353503738617	0.678514401603869	0.636264209370591	1.98953172289536	0.616795999791467	0.324646384071874	NA	NA	0.759623728876731	0.0438935010690998	74.3794577782285
a4142	loss_cnaOV58	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	3.3023701183387	2.83179567410513	0.470574444233566	1.34841172944746	1.22898209689085	0.377799123043739	0.348984241205312	0.382897721149926	0.324700732491231	NA	NA	0.22675517379746	0.498324741711226	74.3794577782285
a4143	loss_cnaOV59	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	3.11855955597693	2.27712110660537	0.84143844937155	1.60966913385821	1.24729112016118	0.653885890896309	0.522740003937773	0.674612715324084	0.324879799518286	NA	NA	0.106557034537254	0.379104390849787	74.3794577782285
a4144	loss_cnaOV84	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	6.01069519329851	6.94297982782679	-0.932284634528282	0.903100578699648	1.60785943257124	0.633046662041751	1.03231539932203	0.579829688866148	0.324912435182108	NA	NA	0.327756933780991	0.137847241782961	74.3794577782285
a4145	gain_cnaOV26	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.12440245971507	2.12560610597118	0.998796353743889	1.3094235288209	1.86994650260025	0.550902138703	0.762775627411612	0.534130977733862	0.324929742459263	NA	NA	0.40002989569941	0.327908601120814	74.3794577782285
a4146	loss_cnaOV59	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	4.38098610538383	3.41472013528582	0.966265970098007	1.38596033129884	1.72226589204757	0.571558539628837	0.697181548617978	0.561043433862138	0.3250147878094	NA	NA	0.695362821480528	0.269722591642338	74.3809807064177
a4147	loss_cnaOV54	292	Masitinib	KIT	10	22	2.99573227355399	NA	4.38460160335027	3.84484715539173	0.539754447958539	0.981571371340941	1.04557329792343	0.525670838480261	0.549888132149955	0.516228225252617	0.325241623708027	NA	NA	0.10119516880314	0.174377394953586	74.3940451129364
a4148	loss_cnaOV84	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	3.78035201299105	3.15498045880651	0.625371554184539	0.968920966092922	0.940859586298726	0.659996953445546	0.645430923748391	0.664681067495635	0.325273227642877	NA	NA	0.181731190542121	0.252583184036092	74.3940451129364
a4149	gain_cnaOV51_(MYC)	1219	PFI-1	BRD2, BRD3, BRD4	8	24	2.30258509299405	NA	2.5859663468214	2.2867921943548	0.299174152466608	0.831866469899122	0.878191016147201	0.344828310839418	0.35964203786563	0.340670932594078	0.325481966529202	NA	NA	0.604114088270937	0.401263650679196	74.3940451129364
a4150	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.60434712655998	1.72130706094526	0.883040065614723	1.88366600859092	1.6200962674656	0.534111841545256	0.468788023772476	0.545054070765875	0.325589218736022	NA	NA	0.336702068992357	0.510022160119498	74.3940451129364
a4151	gain_cnaOV95_(MECOM)	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	2.61205589408733	2.98784630942941	-0.375790415342081	0.562937100217801	0.888263201438695	0.442392180479493	0.66755311596391	0.423062009923887	0.325589841269313	NA	NA	0.322592964089692	0.317077809535888	74.3940451129364
a4152	loss_cnaOV54	211	TL-2-105	CRAF	10	22	2.32630161961136	1.63315443905142	4.6146224484925	4.3157536033075	0.298868845185005	0.714198257437054	0.576381624166916	0.481311602284756	0.418467620262076	0.518525977674915	0.325604664742251	NA	NA	0.266169973410854	0.263763720440312	74.3940451129364
a4153	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	8	23	2.30258509299405	NA	4.78188559615174	4.41767495381935	0.364210642332399	1.04805440763443	0.86840651443355	0.398042298710968	0.347511197586068	0.419401094163796	0.325640306760957	NA	NA	0.523910885352783	0.396854468365355	74.3940451129364
a4154	gain_cnaOV51_(MYC)	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.78705812742168	4.40269851303523	0.384359614386444	0.57515738263596	0.682498538998359	0.580849173134912	0.668268592198043	0.563165475710078	0.325699123133286	NA	NA	0.0510004495269227	0.163634587820466	74.3940451129364
a4155	loss_cnaOV84	1019	Bosutinib	SRC, ABL, TEC	6	25	0.693147180559945	NA	2.51413036242457	1.53374314515634	0.980387217268224	1.04902479193992	1.64891908406321	0.627643306281745	0.93457011197536	0.594563570003925	0.325957929779125	NA	NA	0.0391947019482202	0.0951580828684089	74.4352410882537
a4156	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.74281764106872	3.80530068427159	0.937516956797124	1.83044451301732	1.48651885341201	0.61235754839114	0.512179937785557	0.630679492994816	0.326155691175509	NA	NA	0.73821481743978	0.474541583837647	74.4624803956615
a4157	TP53_mut	261	TL-1-85	MAP3K7 (TAK1)	22	10	2.32630161961136	NA	3.44288540209399	3.8035678819794	-0.360682479885403	0.984424170907338	0.872620035701238	0.378763814346645	0.366389296956173	0.413332796783148	0.326276974967901	NA	NA	0.725709777486229	0.310833534661725	74.4722506945803
a4158	loss_cnaOV84	196	Phenformin	AAPK1 (AMPK) agonist	6	25	8.29404964010203	NA	8.12609313454906	8.90904831564373	-0.782955181094673	1.74701639648043	1.68219286146331	0.462316945258909	0.448167047929275	0.465437227223516	0.326614855742907	NA	NA	0.920938019447325	0.352142826120963	74.4795803102471
a4159	gain_cnaOV26	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.69328033853773	1.1447148536348	1.54856548490294	2.39434290849033	2.29277836946082	0.673380425269066	0.646760110847835	0.67541002023109	0.32665539398601	NA	NA	0.358490878494554	0.380217467118704	74.4795803102471
a4160	loss_cnaOV81_(RB1)	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.24929444509919	3.60426282055012	-0.354968375450931	0.757788999838401	0.932276840374908	0.387163589461942	0.468426403031224	0.380754256759379	0.326763435989079	NA	NA	0.139008412273488	0.438404710575154	74.4795803102471
a4161	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.73859283801643	4.23454664061739	0.504046197399046	0.827216548764787	0.784455700143098	0.638852578980631	0.609327990538507	0.642542590113246	0.326852597190286	NA	NA	0.220193909791824	0.318525243612474	74.4795803102471
a4162	PIK3R1_mut	333	T0901317	LXR	5	27	2.32630161961136	NA	3.93293701541975	4.90528040622208	-0.972343390802325	2.12118724663377	0.790334767660982	0.910176227213585	0.458395831082517	1.23029307400964	0.326858063899888	NA	NA	0.00471695947303226	0.366108459246795	74.4795803102471
a4163	loss_cnaOV56	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.33819726633067	5.90812495652186	0.430072309808812	0.973996280616447	0.67338049931691	0.617298778979854	0.441554365625109	0.638676513865615	0.327127809206032	NA	NA	0.907771671502541	0.52677388662609	74.4795803102471
a4164	gain_cnaOV94	1001	AICAR	AAPK1 (AMPK) agonist	7	24	7.60090245954208	NA	8.41365343902366	8.84756097250691	-0.433907533483252	1.37799194002962	1.19021689819023	0.352364025329444	0.314883941537367	0.364561731683547	0.327175443534688	NA	NA	0.52546583068651	0.469999484531213	74.4795803102471
a4165	loss_cnaOV20	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.8298931096271	4.30524595941018	0.524647150216921	1.01712316282071	0.967066950290304	0.538713070217742	0.515814769926146	0.54251378362111	0.327201025833207	NA	NA	0.507069180344157	0.330906482875131	74.4795803102471
a4166	loss_cnaOV81_(RB1)	1262	UNC1215	LMBL3	4	29	0	NA	3.05931088442526	2.74194399007253	0.317366894352737	0.345934762875024	0.499995990911509	0.651382382955831	0.917418335512561	0.634738878154137	0.327232714901718	NA	NA	0.106286901437895	0.167655730534741	74.4795803102471
a4167	loss_cnaOV52, loss_cnaOV53	1059	AZD8055	MTORC1/2	9	24	0.693147180559945	NA	0.706864310501864	0.121471485759299	0.585392824742565	0.884365883339731	1.18614820254077	0.524494724085424	0.661935106012774	0.493524184826679	0.327359195428076	NA	NA	0.142881457196654	0.14106813031226	74.4795803102471
a4168	loss_cnaOV43_(NF1)	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.99672404845949	4.44462498500283	0.552099063456658	1.05715617862023	0.962292662879045	0.566225329557758	0.522249289766478	0.573733007383487	0.327387580670158	NA	NA	0.320689262165358	0.323187209138758	74.4795803102471
a4169	loss_cnaOV87, loss_cnaOV88	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.42288169545269	-0.408111487582648	0.830993183035338	1.28182859697437	1.40473759060738	0.594784037100832	0.648287286612902	0.591564708306861	0.32749236796903	NA	NA	0.88785098419532	0.380098546538444	74.4795803102471
a4170	loss_cnaOV40	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-1.5214316902619	-2.81871426577549	1.29728257551359	3.13226139689284	1.5852050862594	0.66542271969644	0.414168043829443	0.818368920689484	0.327507894783158	NA	NA	0.336046094172481	0.474837560899552	74.4795803102471
a4171	loss_cnaOV33_(ZFHX3)	293	MP470	PDGFR	4	28	2.99573227355399	NA	4.8074457677107	3.94092800751808	0.866517760192624	1.34553726404057	1.79652210238633	0.493280918920428	0.643993877650419	0.48233069832073	0.327566295988726	NA	NA	0.618566399420734	0.305448042520399	74.4795803102471
a4172	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.67920557831862	4.20363185296319	0.475573725355439	1.15357517436941	0.836608476284102	0.53709778117817	0.412260714274998	0.568454347328343	0.327660939003492	NA	NA	0.517209321927796	0.420651457752135	74.4795803102471
a4173	PIK3R1_mut	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	-0.602276116030472	0.25389401795888	-0.856170133989351	0.964817834319316	1.34660538335367	0.654820474958389	0.887390451891247	0.635798835035912	0.32768125190158	NA	NA	0.867367835937753	0.264658483932745	74.4795803102471
a4174	loss_cnaOV20	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	4.9213498169568	4.19834430029989	0.723005516656909	1.04098991806982	1.32654477856779	0.5590622757347	0.694536521542388	0.545029107451242	0.327764375203802	NA	NA	0.366319939503781	0.216413916071674	74.4795803102471
a4175	loss_cnaOV85	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	25	1.6094379124341	NA	0.796075207361954	1.4704151664051	-0.674339959043142	1.86942113740678	1.19437348894701	0.504997417069866	0.360721265823799	0.564597226314575	0.327936684696903	NA	NA	0.576760184955765	0.431338216934724	74.4795803102471
a4176	TP53_mut	1161	ZG-10	IRAK1	17	6	2.30258509299405	NA	1.74184244940231	1.11232059190834	0.629521857493966	1.34258475705989	0.82236238346154	0.508211647100256	0.46888798206867	0.765504198823083	0.327977337390323	NA	NA	0.157806328624427	0.198626626973101	74.4795803102471
a4177	loss_cnaOV81_(RB1)	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.914072266652113	0.193820875383845	0.720251391268267	0.404084399004761	1.17330828998928	0.641847184504505	1.78242810918266	0.613863719717558	0.327979582981702	NA	NA	0.142897511171185	0.0316978179134296	74.4795803102471
a4178	loss_cnaOV85	1017	Olaparib	PARP1, PARP2	7	24	1.6094379124341	NA	4.48819178987625	3.81839132866713	0.669800461209125	1.08521827418587	1.15525782084887	0.586967780913174	0.617203448505885	0.57978439887727	0.328058424455352	NA	NA	0.0797388127915484	0.186312171720363	74.4795803102471
a4179	loss_cnaOV57_(ZNRF3)	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.40260857885607	5.01334687066512	0.389261708190945	0.473069149870096	0.621513872087013	0.639915511687592	0.822843147345025	0.626312180102792	0.328110224257177	NA	NA	0.107046564809223	0.205007032068651	74.4795803102471
a4180	ARID1A_mut	292	Masitinib	KIT	8	24	2.99573227355399	NA	3.43732826513728	4.20558447212594	-0.768256206988659	0.679207599719918	1.08068810627083	0.767098037653842	1.13110661203653	0.710895403151707	0.328114502121014	NA	NA	0.101260467213255	0.0290315821865424	74.4795803102471
a4181	loss_cnaOV21, loss_cnaOV22	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.16376557726701	4.46849258314094	0.69527299412607	0.356860315640753	1.03482691126489	0.692520304472443	1.94830571978195	0.671873708112429	0.328344793704734	NA	NA	0.186880595460232	0.0448183664206828	74.5140284844837
a4182	loss_cnaOV84	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	6	25	2.30258509299405	NA	2.01533916503743	1.26350955952895	0.751829605508483	2.5755346447661	1.07172759669632	0.519523266692088	0.291912052915429	0.701511846691319	0.328550366342429	NA	NA	0.471723506578102	0.51245929571996	74.5357944841146
a4183	loss_cnaOV1	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.41726798902373	2.24707002848696	-0.829802039463235	1.91742796161951	1.22903229701035	0.644070619413388	0.432768300073377	0.675166992341658	0.328637464955505	NA	NA	0.683327179278362	0.533998103456216	74.5357944841146
a4184	loss_cnaOV38	263	FR-180204	ERK	8	24	2.99573227355399	NA	4.57308432060698	4.89132554158324	-0.318241220976258	0.787344494713978	0.724776660368821	0.430143332997543	0.404195651475111	0.439088671556163	0.328680049208772	NA	NA	0.762833469136149	0.333964250871251	74.5357944841146
a4185	NF1_mut	304	SB52334	ALK5	4	28	2.99573227355399	NA	4.91940900828546	4.28767354323712	0.631735465048335	0.42947211392366	1.0966930503778	0.602088037751407	1.47095805424198	0.576036717685689	0.328754927363108	NA	NA	0.346888718837154	0.059795988301727	74.5357944841146
a4186	loss_cnaOV44	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.630860701733558	-0.00466148429997156	-0.626199217433587	1.50727486565211	0.90148790694359	0.656449481374057	0.415451243634098	0.694628527582423	0.32893156356584	NA	NA	0.544808471317597	0.5485223094497	74.5427416064839
a4187	loss_cnaOV43_(NF1)	290	KIN001-260	IKK	5	26	2.99573227355399	NA	4.51427644452629	4.91485603209445	-0.400579587568155	1.08998070626956	0.861756536409215	0.446728495157574	0.367510713964041	0.464840788138723	0.328942694746259	NA	NA	0.661977429337062	0.472550928319344	74.5427416064839
a4188	gain_cnaOV49	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.0815422637201	5.58604271619069	-0.504500452470589	0.329807430977325	1.00724560872643	0.516477236558713	1.52968188429107	0.500871334756659	0.329085711358016	NA	NA	0.299268588201833	0.0992636345444727	74.5573441868736
a4189	gain_cnaOV50	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	3.79750243878274	4.37828895648448	-0.580786517701744	0.768617404789283	1.35101490984418	0.444688042627877	0.755624988561074	0.429889051164305	0.329292068487941	NA	NA	0.366368248984911	0.252731313864899	74.5847206182847
a4190	loss_cnaOV42	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	3.28941766436382	2.14550012153756	1.14391754282627	1.6225009996731	1.77807794667769	0.648618314500707	0.705033490307089	0.643344992250569	0.329562290627895	NA	NA	0.107163848792023	0.260554032322097	74.5847206182847
a4191	loss_cnaOV81_(RB1)	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	2.46727958182397	1.43643303408051	1.03084654774346	0.511785861057175	1.67397081027283	0.645775072565599	2.01421458891826	0.615809153551157	0.329635165305057	NA	NA	0.0759249679767951	0.0227440869097589	74.5847206182847
a4192	gain_cnaOV19	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.46151753611131	3.61830328431187	0.843214251799441	0.632265285449772	1.23851105235942	0.697672619032276	1.33363996285136	0.680829008504269	0.329648705882408	NA	NA	0.193830387934313	0.124940059322248	74.5847206182847
a4193	SMAD4_mut	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.35059692621973	2.93629101945639	0.414305906763334	1.40890568545417	0.951268227349625	0.412364644298804	0.294062200927083	0.435530058559458	0.329651118943174	NA	NA	0.084728946148748	0.60403365021661	74.5847206182847
a4194	loss_cnaOV41	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.89844875503103	1.25714945867315	0.641299296357887	1.62233727306239	1.30946185661629	0.476729037143807	0.395293449152742	0.489742632148931	0.329678189722997	NA	NA	0.576807483369533	0.496581205256991	74.5847206182847
a4195	loss_cnaOV42	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.98756972509868	1.56117487397239	0.42639485112629	0.910311967961553	0.6421387521525	0.632843179812788	0.468405190894182	0.66402292292278	0.329881178747337	NA	NA	0.204507298023538	0.424243507573764	74.6128534451044
a4196	gain_cnaOV48_(SOX17)	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	1.91408245690781	2.13543512436356	-0.221352667455749	0.320395501915084	0.572617255623024	0.395424536064917	0.690873205562091	0.38656304063857	0.330181406028384	NA	NA	0.0404402342785067	0.364814867891957	74.6255994907485
a4197	gain_cnaOV72_(ASXL1)	170	Shikonin	unknown	4	14	2.77258872223978	NA	0.378600350702258	-0.122675715717206	0.501276066419464	0.630269544758005	0.801059502909425	0.649388502187879	0.79533601232776	0.625766331463323	0.330186358806187	NA	NA	0.576586370900105	0.235481960447675	74.6255994907485
a4198	ARID1A_mut	1067	CCT007093	PPM1D	9	24	1.88706964903238	NA	4.11338755883949	4.63085566524228	-0.51746810640279	0.70042680560422	0.651660394555136	0.77863000209764	0.738789695457755	0.794076348242778	0.330269851970135	NA	NA	0.0786095945436043	0.0753964199407828	74.6255994907485
a4199	SMAD4_mut	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.70438244890249	4.88772826661606	0.816654182286429	0.667994942955654	1.25331109048698	0.667726973695638	1.22254545621709	0.651597347605944	0.330305651804798	NA	NA	0.367740533304517	0.150103434062939	74.6255994907485
a4200	gain_cnaOV96	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	0.333235611175363	-0.120025271235761	0.453260882411124	0.197328056002158	1.0097492272514	0.472165199922158	2.296991576333	0.448884604393241	0.330331272863198	NA	NA	0.544847030047401	0.0444950587005975	74.6255994907485
a4201	loss_cnaOV56	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.45004160148457	5.0218628237791	0.42817877770547	0.567619838469522	0.612035063764116	0.702883267645313	0.754340755354802	0.699598443056677	0.330469850769933	NA	NA	0.10710120880794	0.320134815797307	74.6255994907485
a4202	loss_cnaOV81_(RB1)	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.46261045346799	3.85373697884769	0.608873474620301	0.807264770620816	1.31807883161923	0.476575015455492	0.75424259397825	0.461940105564333	0.330488083352939	NA	NA	0.56934456633025	0.248391570618461	74.6255994907485
a4203	loss_cnaOV21, loss_cnaOV22	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	2.70452312951613	3.36429478494507	-0.659771655428945	0.924891240647605	1.10965829917377	0.600716451054286	0.713350528616722	0.594571910938887	0.330664486884913	NA	NA	0.950420821241337	0.342784051165358	74.641347113477
a4204	gain_cnaOV96	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.37825145649603	2.55536625300716	0.822885203488867	1.1246107476513	1.74443047000007	0.485653807982033	0.731706686253379	0.471721411452321	0.330715157085001	NA	NA	0.636726201435846	0.258014059682391	74.641347113477
a4205	loss_cnaOV20	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-1.97189824850045	-2.87297643222499	0.901078183724544	1.67840737205434	1.76188731423589	0.514611688530103	0.536865005914292	0.511427817456833	0.33105106261945	NA	NA	0.693311988444396	0.317557406667982	74.6711404844397
a4206	KRAS_mut	1022	AZD7762	CHEK1, CHEK2	7	24	0.693147180559945	NA	-1.15066336021135	-0.717660163433099	-0.433003196778254	0.613754901929423	0.831769275152051	0.546994351590904	0.705498555558659	0.520580898710282	0.331058826075897	NA	NA	0.0757897114995109	0.155619007101681	74.6711404844397
a4207	loss_cnaOV43_(NF1)	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.40979710223706	2.57756757328866	0.832229528948402	2.3681131600509	1.09641989047357	0.63448261766117	0.351431486884906	0.759042713634961	0.331083257818806	NA	NA	0.940008003317387	0.607136516808909	74.6711404844397
a4208	loss_cnaOV20	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	1.74297701426631	1.06517689440373	0.677800119862576	2.4367206053473	1.28390762168938	0.456779439777037	0.278160786417272	0.527919694853681	0.331511550794243	NA	NA	0.811262872048167	0.573687868132291	74.73428244109
a4209	gain_cnaOV96	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.78320056068718	4.34429828931851	0.438902271368664	0.924521428335992	0.847075330540275	0.5134099665663	0.474734557703683	0.518138417617152	0.331520751461485	NA	NA	0.868241638281212	0.422967336633953	74.73428244109
a4210	loss_cnaOV81_(RB1)	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.36089524830627	3.60310586705051	0.757789381255763	0.893679603274827	1.23646197301909	0.627543051277735	0.847943019488076	0.612869136125111	0.331699548139667	NA	NA	0.19388931319525	0.194730682481498	74.7568271537695
a4211	SMAD4_mut	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-2.62168265626307	-3.41792958296807	0.796246926704999	1.65509475671262	1.83524275901195	0.438115760797225	0.481088423170719	0.433864633327134	0.331900421130759	NA	NA	0.135473767148888	0.424196726674964	74.7693339885766
a4212	gain_cnaOV19	158	PF-562271	FAK	3	15	0.940007258491471	NA	2.98518471042962	2.15029085749654	0.834893852933081	1.39621326906973	1.37182509745408	0.607240894930925	0.597970146415636	0.608600800847376	0.331912644897426	NA	NA	0.741974010374127	0.416719202282533	74.7693339885766
a4213	loss_cnaOV42	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	5.16384575113885	5.59230294843339	-0.428457197294547	2.24970682109937	0.706862951590204	0.438250237709471	0.190450237015849	0.606138992474655	0.332031717220912	NA	NA	0.299364538643346	0.729782613850193	74.7784035287073
a4214	gain_cnaOV50	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.04573894351027	4.58069084937103	-0.534951905860757	0.33058598211655	0.955596247276467	0.587184413180591	1.61819295069855	0.559809550723349	0.332375312834595	NA	NA	0.52410959257872	0.050087059606633	74.8276997651383
a4215	loss_cnaOV44	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.68917877984194	0.759340322143794	0.929838457698148	0.517762291079603	1.36648035328367	0.70007815305072	1.7958790621065	0.680462368495629	0.332571911306946	NA	NA	0.159344476392661	0.0573747907589133	74.8276997651383
a4216	gain_cnaOV95_(MECOM)	1149	TW 37	BCL2, BCL2L1	8	25	1.6094379124341	NA	-0.453221830025284	-0.832287008062951	0.379065178037667	0.871954857943324	0.928358068570062	0.413860268554998	0.434730278275835	0.40831785802383	0.332644367748132	NA	NA	0.0400974485406801	0.312102315528761	74.8276997651383
a4217	loss_cnaOV83	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	0.54106432238514	1.27980416081108	-0.73873983842594	2.35119258158213	1.30212204288502	0.499188551150312	0.314197928409947	0.56733532963559	0.332823498583223	NA	NA	0.81127887053481	0.527910863972221	74.8276997651383
a4218	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.20721270027391	4.44654593541928	-0.239333235145371	1.02472603610261	0.545591809188673	0.379373689533206	0.233558265051641	0.438667207085227	0.332847258767406	NA	NA	0.266403992566636	0.635033610741188	74.8276997651383
a4219	loss_cnaOV43_(NF1)	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	3.65304012196562	2.38986381207889	1.26317630988674	1.96243723452604	2.35381932800976	0.547902343494231	0.643677304763233	0.536649646323874	0.332910113080193	NA	NA	0.38123088912801	0.245680338937072	74.8276997651383
a4220	loss_cnaOV58	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	3.09031214859849	2.21062227417925	0.879689874419236	2.1322825028147	1.4210955040136	0.574385360216047	0.412557845059464	0.619022347150298	0.332933023421045	NA	NA	0.237676303584244	0.418070072316613	74.8276997651383
a4221	loss_cnaOV81_(RB1)	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	2.09190770257871	1.22899335970344	0.862914342875271	1.26319217994229	1.19548585022387	0.719024313265883	0.683121979835796	0.721810586644487	0.332938833285257	NA	NA	0.0943107475702285	0.358518105573797	74.8276997651383
a4222	gain_cnaOV18_(CCNE1)	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	3.07310353588448	2.46310543299587	0.609998102888614	0.907987260971698	1.03486350412129	0.596124541439857	0.671813503457982	0.589447884150257	0.332962069912776	NA	NA	0.390571729318861	0.28125692402069	74.8276997651383
a4223	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	9.32313867612517	8.59253316522965	0.730605510895524	1.680449599745	1.69788701161007	0.431215310264824	0.434767880575763	0.430302785697564	0.33329575717592	NA	NA	0.920975565495174	0.33671587065231	74.8276997651383
a4224	gain_cnaOV72_(ASXL1)	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.30724898157281	4.90786214117835	0.399386840394452	0.158186485525558	0.863724377089704	0.485272948662265	2.52478483903055	0.462400797046132	0.333342403826487	NA	NA	0.447501572921246	0.0768232478937481	74.8276997651383
a4225	loss_cnaOV87, loss_cnaOV88	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.596965282362202	-0.187195862006544	0.784161144368746	0.273634105899705	1.29078796083189	0.628558748196957	2.86572882349748	0.607505777992668	0.333566056961813	NA	NA	0.764770278767554	0.0157557418002406	74.8276997651383
a4226	loss_cnaOV44	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.77831031799271	1.61047963748135	1.16783068051135	1.54719334332702	1.57438176718297	0.742648327050094	0.754805910682179	0.741770963596042	0.333609283120797	NA	NA	0.0392941541768407	0.319792346704185	74.8276997651383
a4227	SMARCA4_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.5133766769054	2.23677266907107	-0.723395992165672	1.00773030553908	1.3130949750518	0.55888733902713	0.717846816940469	0.550909116179607	0.333693303864098	NA	NA	0.683434344160941	0.341419066078189	74.8276997651383
a4228	loss_cnaOV40	254	AC220	FLT3	7	25	0.0237165266173161	NA	2.70730193891661	2.45580437551397	0.251497563402635	0.567638402502569	0.639090445120123	0.402104402291778	0.443059458792513	0.393524211358478	0.333701890717848	NA	NA	0.856688303958676	0.33618265273562	74.8276997651383
a4229	gain_cnaOV94	1005	Cisplatin	DNA crosslinker	7	24	1.79175946922805	2.30258509299405	3.54690588145964	2.87092825805999	0.675977623399645	0.6091390205686	1.27246418580613	0.579446993338547	1.10972635239925	0.531235087745435	0.333851910850815	NA	NA	0.0854411117057428	0.0644710093911561	74.8276997651383
a4230	loss_cnaOV82	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.83111037564899	5.2280085569901	-0.39689818134111	0.250890734564761	0.792616773716661	0.516474557212066	1.58195631269381	0.500744110523948	0.333852725371016	NA	NA	0.32883506981446	0.0923757417975302	74.8276997651383
a4231	ARID1A_mut	1003	Camptothecin	TOP1	9	22	-2.30258509299405	NA	-4.42666606469631	-3.39028229554677	-1.03638376914954	1.49328729615067	1.73840762903946	0.618967076831798	0.694028384103369	0.596168442796228	0.333882659386932	NA	NA	0.240400578718179	0.112909781360702	74.8276997651383
a4232	gain_cnaOV4_(KRAS)	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.51020089896832	0.835460636893806	0.674740262074513	1.02633041944606	1.2836370859107	0.536109280483653	0.657429858152984	0.525647217177278	0.333992401227634	NA	NA	0.957012341991709	0.295399023124313	74.8276997651383
a4233	loss_cnaOV82	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.72509627754566	3.88869448516099	0.836401792384668	0.965939952246404	1.16160940156546	0.727821671840289	0.865894189840187	0.720037037628552	0.334055794380874	NA	NA	0.0798602882089677	0.267844251661996	74.8276997651383
a4234	loss_cnaOV16, loss_cnaOV17	268	YM155	BIRC5 (Survivin)	6	24	1.63315443905142	NA	-5.00050520814063	-3.9388207404759	-1.06168446766472	0.690554751530322	2.54589424887189	0.456483017456682	1.5374370610179	0.417018290581065	0.334190341943848	NA	NA	0.927266369728243	0.0835105810163494	74.8276997651383
a4235	loss_cnaOV20	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-0.139719141003251	-0.683954204612931	0.54423506360968	2.15121313653835	1.81020301899478	0.290275169671175	0.252989838322316	0.300648633274238	0.334205373007604	NA	NA	0.0393668354460833	0.665602903905154	74.8276997651383
a4236	loss_cnaOV102	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.92089320240022	4.44326755705703	0.477625645343198	0.603560484483883	0.670881915769221	0.716663408777219	0.79134677902518	0.711936980437997	0.334227588564907	NA	NA	0.0511323749046128	0.301770627786295	74.8276997651383
a4237	loss_cnaOV20	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	5.99384991340677	5.45446725902432	0.539382654382451	0.873544979174154	0.981306986800087	0.557425189756101	0.617464088560593	0.54965740755735	0.33425295483313	NA	NA	0.299436138132017	0.259942757194103	74.8276997651383
a4238	loss_cnaOV39	1020	Lenalidomide	TNFA	10	21	1.6094379124341	NA	4.69834330241153	4.25782085142155	0.440522450989981	0.815651923515643	0.716572971027475	0.58836268326523	0.540086326396719	0.614762862682816	0.334316011036042	NA	NA	0.0411055669993115	0.163677050972183	74.8276997651383
a4239	gain_cnaOV96	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.9847866277084	1.56157245931386	0.423214168394533	0.943099063170414	0.637134588554985	0.627904507332649	0.44874837111153	0.664246104350383	0.334360230327052	NA	NA	0.204641848607949	0.441542654075461	74.8276997651383
a4240	gain_cnaOV72_(ASXL1)	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.90073648072796	4.46176562209775	0.43897085863021	0.545346706882581	1.03205207558366	0.446613090565005	0.804939047197227	0.425337896231599	0.334379908821485	NA	NA	0.320909783661504	0.189717479809107	74.8276997651383
a4241	gain_cnaOV18_(CCNE1)	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	-0.282172165926828	-1.46528861063392	1.1831164447071	1.02129088089573	1.91319507934092	0.641768313978165	1.15845198154461	0.618398226862817	0.334509670871183	NA	NA	0.0714225388315625	0.10322793993638	74.832372948304
a4242	gain_cnaOV4_(KRAS)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	8	24	0.246860077931526	2.32630161961136	0.53528708211046	1.16047463696602	-0.625187554855563	1.24068524524425	1.61621709166176	0.40680524179826	0.503905045419062	0.386821521737998	0.334731361050338	NA	NA	0.788962175272084	0.271830244948479	74.832372948304
a4243	gain_cnaOV94	1043	JNK Inhibitor VIII	JNK	7	26	2.30258509299405	NA	4.83180776486824	4.33709764953163	0.494710115336606	0.856542226613817	1.02692739019918	0.496583977258094	0.577566522659778	0.48173816382544	0.334779171698551	NA	NA	0.37038512288457	0.220673616049099	74.832372948304
a4244	loss_cnaOV43_(NF1)	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	3.69494791844385	2.68659780212895	1.00835011631491	1.43684039510653	1.88278645675032	0.55112607365973	0.70178296750917	0.53556265645511	0.33480046623345	NA	NA	0.341589733157561	0.214874144133486	74.832372948304
a4245	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	193	GW-2580	CSF1R (cFMS)	7	25	2.99573227355399	NA	5.91274400930716	5.67431885230083	0.238425157006337	0.756415392282401	0.55515707520158	0.396828702488034	0.315203999599896	0.429473328642644	0.334893651862091	NA	NA	0.1880610795578	0.459571023994481	74.832372948304
a4246	loss_cnaOV81_(RB1)	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	5.01426999994413	4.52760393484173	0.4866660651024	0.589976230033165	0.968588799908715	0.519037015633953	0.824890970734605	0.502448577918995	0.334967241811656	NA	NA	0.94257298817106	0.213339348286411	74.832372948304
a4247	NF1_mut	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	3.37323181371533	4.05799285786235	-0.684761044147024	1.70173579522544	1.07188678256353	0.59383867306478	0.402389751727771	0.638837100415908	0.335164706054372	NA	NA	0.0798824421114857	0.485529181149596	74.832372948304
a4248	gain_cnaOV51_(MYC)	306	TG101348	JAK2	8	24	2.32630161961136	NA	2.45962165915627	2.94553760460633	-0.485915945450058	1.46597532106458	1.36809848736751	0.349189851034686	0.331462568617588	0.355176144069171	0.335335816297822	NA	NA	0.624031842614306	0.426167301445446	74.832372948304
a4249	loss_cnaOV81_(RB1)	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	4.98683114507745	4.21424361768521	0.772587527392244	0.957651706808459	1.32577909720886	0.596714126587221	0.806752101938007	0.582742275103566	0.335341951975435	NA	NA	0.366556664211381	0.213598190684384	74.832372948304
a4250	loss_cnaOV36	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.8103485626579	0.920780767451536	0.88956779520636	1.0766399729137	1.56673163877445	0.578045958512719	0.82624444344095	0.567785684025765	0.335374580777421	NA	NA	0.788971102920193	0.286671684175614	74.832372948304
a4251	gain_cnaOV26	151	QS11	ARFGAP	3	16	2.32630161961136	NA	4.66904324867256	3.59760501900471	1.07143822966785	0.571428224564054	1.49678765007828	0.754755725695061	1.87501804007888	0.715825140334246	0.335374670963717	NA	NA	0.0603255289344581	0.0617719469582696	74.832372948304
a4252	TP53_mut	1194	SB-505124	TGFR1 (ALK5)	22	10	2.30258509299405	NA	4.69992934388115	4.34315446099595	0.356774882885198	0.954406281214098	0.89441346080119	0.380839392273906	0.373818666020665	0.398892568729465	0.335400539289252	NA	NA	0.942574662513506	0.318994368481696	74.832372948304
a4253	gain_cnaOV49	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	2.85944528973816	3.31930251612872	-0.459857226390556	0.156533434989157	1.07641065011328	0.441874439840862	2.93775720453851	0.42721356049586	0.335474402475965	NA	NA	0.0888847774537662	0.0460824241912808	74.832372948304
a4254	loss_cnaOV54	1018	ABT-888	PARP1, PARP2	10	21	1.6094379124341	NA	4.56872747646908	4.17142170876402	0.397305767705058	0.662373934416941	0.834255657632934	0.506153463804409	0.599820957711431	0.476239824171344	0.335645781805345	NA	NA	0.22047419700346	0.166258711677718	74.832372948304
a4255	loss_cnaOV21, loss_cnaOV22	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	4.96474008813564	3.78878242214439	1.17595766599124	0.18632750193867	1.75256208152446	0.695110190367229	6.31124044360513	0.670993443478101	0.335717372384373	NA	NA	0.143303067504265	0.00212283228841412	74.832372948304
a4256	loss_cnaOV35	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.90785498861573	4.35885422495791	0.549000763657815	1.03626552433568	0.991485836239284	0.550444668350489	0.529787733708271	0.553715185423304	0.335769504914179	NA	NA	0.370415560569163	0.318680840868664	74.832372948304
a4257	PIK3R1_mut	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	0.87480675698231	2.25803187159056	-1.38322511460825	1.01076127598919	2.041295709102	0.714530542420844	1.36849832642682	0.677621134674676	0.335871669957437	NA	NA	0.128781373503048	0.0406824285440878	74.832372948304
a4258	loss_cnaOV39	291	KIN001-266	MAP3K8 (COT)	9	23	2.99573227355399	NA	3.00702043925169	3.41804061733436	-0.411020178082664	0.987309000804098	1.13779754172528	0.37376250696235	0.416303485279598	0.361241928383339	0.335879017246045	NA	NA	0.950438356773567	0.32535956813352	74.832372948304
a4259	loss_cnaOV84	163	JQ1	BRD4	5	14	0.940007258491471	NA	0.702192013037285	-0.130660644242994	0.832852657280279	1.92616411718447	1.82503670841877	0.45035397827992	0.432389249623071	0.456348441342789	0.33589928582445	NA	NA	0.575058683753594	0.428903355211648	74.832372948304
a4260	loss_cnaOV21, loss_cnaOV22	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.86654693221855	-2.04927874129559	-0.817268190922967	2.07571494494785	1.20712989457754	0.637960307632829	0.393728528530444	0.677034173864933	0.336004921793512	NA	NA	0.604116131018045	0.567576902228339	74.8383349499852
a4261	PIK3R1_mut	255	CP724714	ERBB2	5	27	2.32630161961136	NA	4.81318089577102	4.3413452286555	0.471835667115514	0.626025591842497	0.981381473928187	0.50100417781643	0.753700285202116	0.480787216439792	0.336248598756302	NA	NA	0.784390586928023	0.198988460519322	74.8437106670231
a4262	loss_cnaOV21, loss_cnaOV22	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.779645776284341	0.414513725058581	-1.19415950134292	0.810373242984955	1.87769366884753	0.655300937420716	1.47359196725735	0.635971415974289	0.336270782722343	NA	NA	0.481456865273096	0.099806121411124	74.8437106670231
a4263	gain_cnaOV49	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.86243603681592	4.31535128045978	0.547084756356147	0.432257737409137	1.08950505163569	0.516867374698816	1.2656447970955	0.502140633065261	0.336332695688221	NA	NA	0.347133856382344	0.145700904907493	74.8437106670231
a4264	loss_cnaOV58	1007	Docetaxel	Microtubules	5	26	-4.38202663467388	NA	-3.93833703743339	-4.7851592062546	0.846822168821206	1.87973101455259	1.30255910414801	0.606421627745906	0.450501780449032	0.650121876331365	0.336394445662645	NA	NA	0.131622586109501	0.381442319926248	74.8437106670231
a4265	KRAS_mut	1495	AZD-2281	PARP1, PARP2	7	26	2.30258509299405	NA	3.1859174731712	3.66228374092892	-0.476366267757712	0.966917723688512	0.8863513856849	0.527825948771285	0.492664738774786	0.537446294383141	0.336423457685796	NA	NA	0.139251618525827	0.269633276732421	74.8437106670231
a4266	loss_cnaOV39	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.262808197302323	0.969596721924042	-0.706788524621718	1.15940621723012	1.00719175575589	0.679983948200054	0.609612501742722	0.701741769213829	0.336642207990021	NA	NA	0.345566353209521	0.327375676827913	74.844709845047
a4267	SMAD4_mut	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.33856596378033	4.69389278229788	0.644673181482458	0.653463040381538	1.25458940797536	0.527271899698458	0.986548804820012	0.51385192429037	0.336978486371061	NA	NA	0.420199287638693	0.224215371262476	74.844709845047
a4268	PIK3R1_mut	326	GSK690693	AKT	5	27	2.32630161961136	NA	4.31602527565173	4.12154334743447	0.194481928217254	0.814494374844308	1.54436939114985	0.132465632664976	0.238776269332037	0.1259296702795	0.33699316837118	NA	NA	0.0905188872679588	0.687515962274997	74.844709845047
a4269	loss_cnaOV85	310	YM201636	FYV1	7	25	1.63315443905142	NA	2.05125626814846	2.44250145653519	-0.391245188386727	1.02378185549572	0.812233261911139	0.455613117580904	0.382156790810953	0.481690675245371	0.337121543373762	NA	NA	0.647359821338372	0.377711659120288	74.844709845047
a4270	loss_cnaOV39	344	THZ-2-49	CDK9	9	23	2.99573227355399	NA	2.10229685799412	2.77699355713091	-0.674696699136785	2.69082401461014	2.18797635635892	0.289235223197211	0.250739808873952	0.308365626153095	0.337189587886423	NA	NA	0.381366506077821	0.514876947058232	74.844709845047
a4271	gain_cnaOV18_(CCNE1)	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	0.991790498505212	0.589569498928443	0.402220999576768	0.140944479166513	0.638084590351403	0.662660686220767	2.85375491083677	0.630356861235685	0.337260925295539	NA	NA	0.0142212466680735	0.00830347348488308	74.844709845047
a4272	loss_cnaOV84	312	AV-951	VEGFR	6	26	-2.05572501506252	NA	0.936340050942879	0.571425679167691	0.364914371775187	0.745043854623865	0.5725143035592	0.603466109675327	0.489789117124406	0.637389091428095	0.337317333994244	NA	NA	0.0142215761626432	0.300616768054563	74.844709845047
a4273	loss_cnaOV82	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.03717183364081	1.57074689209308	0.466424941547728	1.01335980343315	0.643936557186572	0.691117067682889	0.460275748029014	0.724333688376986	0.337388699143292	NA	NA	0.204731481956467	0.51091136289484	74.844709845047
a4274	RB1_mut	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	1.91108306919827	2.59964074976077	-0.688557680562507	0.45176610926327	1.0515419625948	0.672742507265859	1.52414638115593	0.654807611161242	0.337424771257786	NA	NA	0.390707746563628	0.0908730889201395	74.844709845047
a4275	gain_cnaOV4_(KRAS)	1033	Vismodegib	SMO	5	26	2.30258509299405	NA	5.22170750308878	4.85118098168274	0.370526521406044	0.75110986696909	0.871495239797092	0.432909846563349	0.49330535744552	0.425161841953735	0.337534678993859	NA	NA	0.150223012791776	0.361939198381332	74.844709845047
a4276	loss_cnaOV16, loss_cnaOV17	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.83939288026878	2.31643018176491	0.52296269850387	1.33392593240645	0.92030559593508	0.534678602945755	0.392047778515279	0.568248960794933	0.337554764229775	NA	NA	0.401833727291998	0.572729459135832	74.844709845047
a4277	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	2.62311899039725	1.77134922381593	0.851769766581322	0.962821789432763	1.40352501968104	0.628733040223972	0.884659836253948	0.60687893314142	0.337658627016318	NA	NA	0.0327147911119011	0.133396387973551	74.844709845047
a4278	gain_cnaOV94	170	Shikonin	unknown	3	15	2.77258872223978	NA	0.360822553412765	-0.0857017518313436	0.446524305244108	0.426746890488802	0.821707215580006	0.570051742015895	1.0463446019083	0.543410471245439	0.337750997045763	NA	NA	0.576965875395897	0.221882174065468	74.844709845047
a4279	gain_cnaOV50	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	-0.642605165217654	-0.0859510539394808	-0.556654111278173	1.33811930429174	1.63913984581069	0.345616757622687	0.415997369960077	0.339601354149781	0.337785197425129	NA	NA	0.0973167916374845	0.489533843305895	74.844709845047
a4280	loss_cnaOV34	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-5.0957472433788	-3.96223971213486	-1.13350753124394	0.769611112608235	2.49289277209271	0.487272560637922	1.47283155437095	0.454695662779108	0.337822730608776	NA	NA	0.927285402336888	0.0746203547727757	74.844709845047
a4281	PIK3R1_mut	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	1.4246000091576	2.28276020936937	-0.858160200211777	1.92463843335656	1.23039380940624	0.641837913429022	0.445881255065218	0.697467911209585	0.337849712488326	NA	NA	0.890161530960001	0.525207089402842	74.844709845047
a4282	gain_cnaOV95_(MECOM)	1017	Olaparib	PARP1, PARP2	8	23	1.6094379124341	NA	4.3365067677977	3.84202957716362	0.494477190634078	0.795078207904396	1.24895318661869	0.427810530044401	0.621922706116398	0.395913310388184	0.337884582361836	NA	NA	0.0799363818611843	0.211940790500223	74.844709845047
a4283	loss_cnaOV70	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.45012704543906	5.75744569171427	0.692681353724783	0.488457796412971	1.31883560574813	0.541012321933903	1.41809867466861	0.525221908405975	0.338066349200634	NA	NA	0.567212112603069	0.113791137743832	74.844709845047
a4284	loss_cnaOV57_(ZNRF3)	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.27267495583638	5.90233243694146	0.370342518894922	0.805989161916269	0.684538589454363	0.531172462020814	0.459488211993346	0.541010433305326	0.338113671386094	NA	NA	0.907838011364373	0.435061313561042	74.844709845047
a4285	loss_cnaOV55	1024	CEP-701	FLT3, JAK2, NTRK1, RET	7	24	0.693147180559945	NA	0.538207768217711	-0.360773062281691	0.898980830499402	0.992048857031717	1.69427134238435	0.57082268563639	0.906186045301457	0.530600269278159	0.338194105243453	NA	NA	0.0973257901157049	0.0956783029740376	74.844709845047
a4286	gain_cnaOV4_(KRAS)	1527	GDC0941 (rescreen)	PI3K	7	24	1.38629436111989	NA	0.679160254220539	0.295691551045022	0.383468703175517	0.789268608575643	0.931438896349365	0.424256306869673	0.485853230457937	0.41169496429499	0.338246810653825	NA	NA	0.908740893612281	0.300806147923953	74.844709845047
a4287	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.78722747788477	2.19894129138685	0.588286186497924	1.38097370295218	1.40923776860656	0.418597878500556	0.42599376457373	0.4174499148427	0.338278614941505	NA	NA	0.525788063408552	0.41954381922675	74.844709845047
a4288	loss_cnaOV84	207	AS601245	JNK 	4	14	2.07944154167984	NA	2.35532667457282	1.89008308898216	0.465243585590657	1.14459506749534	0.94011281762757	0.473914827047512	0.406470024904726	0.494880589719781	0.338293945514297	NA	NA	0.471049098436304	0.495876219255558	74.844709845047
a4289	loss_cnaOV35	219	AT-7519	CDK9	5	27	2.32630161961136	NA	0.946948268752321	1.59970019445149	-0.652751925699173	0.789239904610697	1.80101071021777	0.383692511380368	0.827064016765792	0.36243644859849	0.33832109572766	NA	NA	0.311487413802055	0.208930374937926	74.844709845047
a4290	loss_cnaOV85	1054	PD-0332991	CDK4, CDK6	7	26	1.38629436111989	0.693147180559945	3.0468317745055	2.07882122155792	0.968010552947582	1.71298339344185	1.76914859952332	0.550500843926856	0.565102123379367	0.547161811737239	0.338451883815189	NA	NA	0.107359489903011	0.217691670623669	74.8449381395261
a4291	gain_cnaOV72_(ASXL1)	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	3.29455796207035	2.55281604206989	0.74174192000046	0.995014004956377	1.37035285947244	0.565376726423122	0.745458773751611	0.541278047382639	0.338500613634967	NA	NA	0.940063076835497	0.266976604200958	74.8449381395261
a4292	KRAS_mut	1036	PLX4720	BRAF	7	26	2.30258509299405	NA	3.81262820194321	4.44123046459917	-0.628602262655964	1.48678453886	1.24293763967004	0.485885237525686	0.422793112402115	0.50573917998238	0.33861840096166	NA	NA	0.366656814243056	0.333434644319167	74.8449381395261
a4293	loss_cnaOV43_(NF1)	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	3.13633673748516	2.31063635538426	0.8257003821009	1.59116658605877	1.4121343362576	0.574482447427056	0.518927678179891	0.584718012231858	0.33863765310524	NA	NA	0.235670872195156	0.325749254368054	74.8449381395261
a4294	MLL2_mut	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	-0.134293929420705	1.92254437827565	-2.05683830769635	0.821847900133177	1.52258392686309	1.38515848085248	2.50269947439551	1.35088665485519	0.339009372520657	NA	NA	0.0393626304383844	0.0237177743371141	74.8822349378839
a4295	loss_cnaOV84	205	BMS-708163	g-secretase	6	26	2.32630161961136	0.940007258491471	5.33800684619794	4.99831175449462	0.339695091703322	0.547760104275685	0.61866050812077	0.559243667878108	0.620153036067693	0.549081583912917	0.33902972021051	NA	NA	0.107295268800531	0.217545301050201	74.8822349378839
a4296	PTEN_mut	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.55845158071652	2.75549282053821	0.802958760178317	0.432885959809156	1.09299339492402	0.767719228857032	1.85489675047977	0.734641914495867	0.339067246750944	NA	NA	0.302212691363349	0.0228895675076651	74.8822349378839
a4297	loss_cnaOV54	1024	CEP-701	FLT3, JAK2, NTRK1, RET	10	21	0.693147180559945	NA	0.424257544812723	-0.434936884064944	0.859194428877668	0.966259555588356	1.77346766392431	0.547930375535324	0.88919630746058	0.48447143771229	0.339319043749069	NA	NA	0.0973504727706692	0.0922911680328152	74.8822349378839
a4298	MLL2_mut	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.70521859088363	3.4594463672134	0.245772223670236	1.31838957590741	0.874347127054527	0.270209885940512	0.186418512525842	0.281092275671089	0.339609979824648	NA	NA	0.792332829852235	0.779719713842755	74.8822349378839
a4299	loss_cnaOV1	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	0.402774183697037	-0.111589231068654	0.514363414765691	0.405428554965586	0.987725653681914	0.535818483129663	1.26869064466698	0.520755346232342	0.339617990908656	NA	NA	0.545097396350681	0.143403520428822	74.8822349378839
a4300	loss_cnaOV59	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.84338662760011	3.19516294023382	0.648223687366291	0.855312880001281	1.04351708607859	0.631642437039187	0.75787902009066	0.621191254090759	0.339692139464587	NA	NA	0.0889703229578243	0.234732589908499	74.8822349378839
a4301	loss_cnaOV1	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.99903836245831	3.49733829100096	0.501700071457355	1.2797354576699	0.865420553289644	0.558063534122079	0.392034203983715	0.579718230114005	0.339696459524176	NA	NA	0.66022406040579	0.569936291320993	74.8822349378839
a4302	loss_cnaOV34	1006	Cytarabine	DNA synthesis	5	26	0.693147180559945	NA	-0.576720209389938	-0.0218072016210363	-0.554913007768901	1.20581843988905	1.26006755858076	0.442964884687491	0.460196153427509	0.44038353657316	0.339739329670977	NA	NA	0.764867988046107	0.386739593439254	74.8822349378839
a4303	gain_cnaOV4_(KRAS)	1001	AICAR	AAPK1 (AMPK) agonist	5	26	7.60090245954208	NA	8.24259923156465	8.84707850982724	-0.604479278262595	1.08690928322157	1.24479537741944	0.493763168096828	0.556145105754306	0.485605336610205	0.339746653957507	NA	NA	0.525829351003642	0.307610007799454	74.8822349378839
a4304	loss_cnaOV102	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	1.98009798838094	2.82856229240297	-0.848464304022034	0.318813581308128	1.73112683402372	0.506711623742593	2.66131794179121	0.490122553325523	0.339887633623633	NA	NA	0.316726619747326	0.0331619503270671	74.8822349378839
a4305	loss_cnaOV38	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	2.7227920780031	3.04319877296782	-0.320406694964722	1.05325724082451	0.437326775305876	0.539072499959291	0.304205546893655	0.732648246247037	0.339961841645168	NA	NA	0.846871335746933	0.590472891563514	74.8822349378839
a4306	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.3627425256153	5.00631237281375	0.356430152801547	0.538808151791537	0.61812522689676	0.586091509435268	0.661515887642785	0.576630975880035	0.339974388984054	NA	NA	0.10731629375664	0.231982519274242	74.8822349378839
a4307	loss_cnaOV52, loss_cnaOV53	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	24	2.99573227355399	NA	4.34726471516266	3.92783162712992	0.419433088032736	1.15680962003554	1.58766711670539	0.279947281803318	0.362577455069789	0.264182008696579	0.340010206442973	NA	NA	0.325160611730545	0.432911557917576	74.8822349378839
a4308	loss_cnaOV84	164	JQ12	HDAC	5	14	1.63315443905142	NA	0.888839150637944	2.11712659561818	-1.22828744498024	2.54758227283596	2.03980187095001	0.566032164272421	0.482138480109973	0.602160171766184	0.340021156490599	NA	NA	0.654721610450162	0.368690437693236	74.8822349378839
a4309	gain_cnaOV50	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	5.63521364533742	5.99025813494132	-0.355044489603895	0.985276183213798	0.659982737209704	0.508573103472674	0.36035022022536	0.53796026711996	0.340069133928841	NA	NA	0.907849512956291	0.52939680654068	74.8822349378839
a4310	loss_cnaOV58	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.96762254167464	3.3066384237997	0.660984117874938	1.46767204717077	1.16079168688687	0.547975875272137	0.450362272109164	0.569425268411108	0.340582108737855	NA	NA	0.322188305260251	0.384449105878814	74.9056503849632
a4311	gain_cnaOV72_(ASXL1)	255	CP724714	ERBB2	5	27	2.32630161961136	NA	4.04619727620227	4.48337923227934	-0.437181956077069	1.40462795417372	0.851457056218853	0.463053298618435	0.311243952377585	0.513451562687735	0.34062184708121	NA	NA	0.784451696647165	0.533284244263812	74.9056503849632
a4312	KRAS_mut	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	2.786488017991	2.01038260760269	0.776105410388304	0.799342192775763	1.40560062368217	0.577095051919578	0.97093011904355	0.552152152832135	0.34062717020835	NA	NA	0.890200993975157	0.243800130885429	74.9056503849632
a4313	gain_cnaOV96	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	1.1385368126587	0.241326795273946	0.897210017384757	1.48343240928018	1.68020355733985	0.540185552829509	0.604820288253053	0.533988880969426	0.340687805150456	NA	NA	0.835611167592202	0.326509715127527	74.9056503849632
a4314	PTEN_mut	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.4707606803621	1.88437008821881	0.586390592143289	0.444216477823216	1.38342952274036	0.437137667741849	1.32005592187117	0.423867340189285	0.340703786864994	NA	NA	0.837522701351983	0.147465300786601	74.9056503849632
a4315	gain_cnaOV26	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.99388790939911	1.26982738128935	0.724060528109759	1.15574072965926	1.35835710545065	0.538189480588232	0.626490448530985	0.533041366813142	0.340810302838378	NA	NA	0.577102059163831	0.395067902746445	74.9056503849632
a4316	loss_cnaOV41	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.392258171288263	-1.48872144092651	1.09646326963825	2.09058345994367	1.80067001767615	0.595268739451228	0.52447715704581	0.608919601523263	0.340831616130485	NA	NA	0.0715355740428268	0.320122336086686	74.9056503849632
a4317	loss_cnaOV39	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	1.98681234207891	1.13413197641359	0.852680365665326	1.67388461746239	1.37451338424756	0.592395231804312	0.50940211575514	0.620350718616031	0.340906322378056	NA	NA	0.853620099597399	0.402603140922995	74.9056503849632
a4318	loss_cnaOV36	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.75518091731385	-4.74429577849446	0.989114861180609	2.39909677340201	1.29664735397692	0.706099060980217	0.412286353825572	0.762824879214011	0.341124116526991	NA	NA	0.131743329737537	0.550957576729398	74.9056503849632
a4319	loss_cnaOV21, loss_cnaOV22	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.76666872448617	-4.12311116385358	-0.643557560632589	1.28375124822517	1.3401337094366	0.481542966818417	0.501310173230468	0.480218918531004	0.341195133456108	NA	NA	0.213463222481283	0.4822186162866	74.9056503849632
a4320	loss_cnaOV55	1022	AZD7762	CHEK1, CHEK2	7	24	0.693147180559945	NA	-0.462727076433027	-0.918308246201778	0.455581169768751	0.763710104660254	0.79575638639553	0.577245547171863	0.596536784034593	0.572513369113326	0.341422178828375	NA	NA	0.0759894044137581	0.198619717979253	74.9056503849632
a4321	KRAS_mut	277	ABT-869	VEGFR and PDGFR family	7	25	0.0237165266173161	NA	2.46974132761471	2.78499833725657	-0.315257009641855	0.4725133494054	0.577555019868229	0.564844656362674	0.667191752441634	0.545847579532391	0.341448410615251	NA	NA	0.132038448231833	0.165013333776661	74.9056503849632
a4322	ARID1A_mut	260	NG-25	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	3.42712431304222	2.87360087346297	0.553523439579251	1.04918204081107	1.06634202802283	0.52103050610973	0.527576167002775	0.519086207832936	0.3414792031805	NA	NA	0.430193388411531	0.221958981374511	74.9056503849632
a4323	loss_cnaOV83	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	5.93937294366154	6.8998467854281	-0.960473841766563	1.02642183581686	1.55835196548394	0.649647156418834	0.935749618968485	0.616339481092959	0.34156812684738	NA	NA	0.32873278386283	0.182919539796464	74.9056503849632
a4324	PIK3R1_mut	1114	Cetuximab	EGFR	5	27	4.18661983833127	NA	5.4200077366637	5.89689879676713	-0.476891060103434	1.50844388717431	1.24686935794818	0.371171559633963	0.316147696416318	0.382470751296828	0.341606756731724	NA	NA	0.5673023990221	0.534519569332592	74.9056503849632
a4325	SMAD4_mut	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	1.49859499075812	2.69985305392013	-1.20125806316201	0.711763348955147	2.3997902561754	0.516516835463989	1.68772115749628	0.500567939248358	0.341611325601757	NA	NA	0.381504220471939	0.0802572791023363	74.9056503849632
a4326	loss_cnaOV56	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.27282289296911	0.258982215861572	1.01384067710754	1.72779660355836	1.65608417495718	0.610332202635375	0.586782422780294	0.612191513232564	0.34170707503201	NA	NA	0.835622425154481	0.419130922572235	74.9056503849632
a4327	PIK3CA_mut	173	FH535	unknown 	5	13	3.46573590279973	NA	2.57254741222863	2.46770291695188	0.104844495276752	1.94418812379993	1.25737758885281	0.0718261989010319	0.0539271349275769	0.0833834611068648	0.341713440523501	NA	NA	0.114800479451372	0.914971542172105	74.9056503849632
a4328	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1020	Lenalidomide	TNFA	8	23	1.6094379124341	NA	4.64027081971211	4.31632627592483	0.323944543787276	0.979092249925407	0.682192577662487	0.423739971941867	0.330862126435947	0.474857913138343	0.341789642903132	NA	NA	0.0412026186224381	0.408093089986371	74.9056503849632
a4329	gain_cnaOV72_(ASXL1)	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	2.90014855310689	2.68194092441417	0.218207628692715	0.609944257994953	0.561584606228464	0.383985569843853	0.357750115412219	0.388556997952938	0.341880253774333	NA	NA	0.132048992610039	0.488500904154459	74.9056503849632
a4330	loss_cnaOV35	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.70318543959211	4.40540606044701	0.297779379145093	0.778270295340547	0.505594454897183	0.541593489506994	0.382616914621924	0.58896883907805	0.341908696012722	NA	NA	0.360360215601006	0.450175892415494	74.9056503849632
a4331	gain_cnaOV50	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.79199065339688	2.33661089810217	0.455379755294711	1.10954181447835	0.916456605862848	0.485709257212578	0.410421445458374	0.496891781216383	0.341912270005079	NA	NA	0.732373836499935	0.481511102623603	74.9056503849632
a4332	loss_cnaOV87, loss_cnaOV88	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	5.03894235128506	4.3823455396015	0.656596811683562	1.22624365466151	0.981433236225539	0.657228141707417	0.535453789454925	0.669018316731095	0.342029875923492	NA	NA	0.370605217186432	0.453817543938227	74.9141181338342
a4333	loss_cnaOV34	306	TG101348	JAK2	5	27	2.32630161961136	NA	3.42006150610289	2.71368771308473	0.706373793018161	1.22539772130207	1.40600113198858	0.510649965143697	0.57644451327002	0.50239916380373	0.342282060313166	NA	NA	0.624191226739979	0.290816842174617	74.9520516242325
a4334	loss_cnaOV21, loss_cnaOV22	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-2.03527328999889	-1.24313620315381	-0.792137086845075	0.876283166338641	1.92367847345966	0.423111292132876	0.903973872001727	0.41178247704797	0.342488201602323	NA	NA	0.071564745690411	0.264005574660465	74.970440603091
a4335	loss_cnaOV33_(ZFHX3)	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	4.60607062448008	4.00944385081446	0.596626773665622	1.39924304692546	1.07420373522148	0.537020102074404	0.426392523426564	0.555413050712034	0.342700012008505	NA	NA	0.817952146713382	0.464537830079314	74.970440603091
a4336	loss_cnaOV52, loss_cnaOV53	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	3.2093344387749	2.89231983661823	0.317014602156673	0.228440638573882	0.665109130293841	0.535422850591899	1.3877329538901	0.476635468853988	0.342840101569211	NA	NA	0.846923874176992	0.140478361884343	74.970440603091
a4337	gain_cnaOV19	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-1.38051089915245	-2.76405675313891	1.38354585398646	2.64961484132478	1.84483425687912	0.707056000981925	0.522168668595886	0.749956723118849	0.342863767592277	NA	NA	0.336938771031318	0.465021302664184	74.970440603091
a4338	gain_cnaOV51_(MYC)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	0.693147180559945	2.36176952195319	2.96628880828988	-0.604519286336683	1.92848827540214	1.42079234311495	0.390003042379086	0.313467960395364	0.425480394278683	0.342994741041422	NA	NA	0.968526332128823	0.433061425518013	74.970440603091
a4339	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1059	AZD8055	MTORC1/2	8	25	0.693147180559945	NA	0.63128904965383	0.169071282220373	0.462217767433457	1.28101118488354	1.08162489854098	0.409140860338064	0.36082258522628	0.42733647131917	0.343005733305179	NA	NA	0.14327462440121	0.37796589300581	74.970440603091
a4340	loss_cnaOV52, loss_cnaOV53	1011	ABT-263	BCL2, BCL2L1, BCL2L2	9	24	0.693147180559945	NA	1.14184579757204	1.96126695136432	-0.819421153792284	1.25133862263334	1.79649547786855	0.489819441130703	0.654835660764534	0.456122024178144	0.34305014079201	NA	NA	0.225139089940565	0.155069434686806	74.970440603091
a4341	NF1_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	3.23207776708845	2.73797498814512	0.494102778943329	0.440361255442942	0.995142166252487	0.517041405315732	1.12203962731991	0.496514765125494	0.343065509610355	NA	NA	0.965884764184462	0.122695963277495	74.970440603091
a4342	gain_cnaOV96	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	3.27840003622328	2.55712482229578	0.7212752139275	0.794439012885243	1.40054717104596	0.548890243805606	0.907905077959317	0.514995302435142	0.343077159525858	NA	NA	0.94009623246757	0.213165061960334	74.970440603091
a4343	loss_cnaOV84	225	Genentech Cpd 10	AURKA, AURKB	6	26	2.32630161961136	NA	3.60544505807531	2.6684696115865	0.936975446488817	1.5721724435429	1.87697671696634	0.512090839837679	0.595974983747544	0.499193963366365	0.343173069258699	NA	NA	0.341853934630573	0.238450198109823	74.9741319505075
a4344	loss_cnaOV1	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.91645687005307	2.91605150146538	1.00040536858769	1.24158982325699	1.63117454144241	0.622088024942138	0.80574546428174	0.61330369201511	0.343258208045384	NA	NA	0.660480437096944	0.295489017082665	74.9754689766199
a4345	loss_cnaOV58	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	1.99944268757792	2.46651312305772	-0.467070435479807	1.26152278203977	0.872883161960504	0.500026414055847	0.370243361538501	0.535089294689523	0.343537125938926	NA	NA	0.732401138895994	0.465391022697096	75.0120388981093
a4346	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	0.693147180559945	3.28485950585069	2.67090001344268	0.61395949240801	1.79058665088649	1.47150678465631	0.396278850307752	0.342881754482001	0.417231846166043	0.343583750083722	NA	NA	0.968527500684249	0.399385849031336	75.0120388981093
a4347	loss_cnaOV56	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.68652646599524	4.88957543726164	0.7969510287336	0.676865040667779	1.25420240376857	0.650990270409418	1.17741496583624	0.635424574485713	0.343674432850937	NA	NA	0.368163163614587	0.16172729586816	75.0145763781003
a4348	loss_cnaOV1	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.2766292582483	-4.14368117985979	0.867051921611495	2.02920162858558	1.46918585211407	0.572511580544497	0.427287219464662	0.590158093588949	0.343973362253578	NA	NA	0.862773748225022	0.539409765731668	75.022595581972
a4349	gain_cnaOV4_(KRAS)	203	BMS-345541	IKBKB	8	24	2.77258872223978	NA	3.57082960055091	3.17797800135584	0.392851599195066	1.24890539280867	0.960571969446501	0.379545100314418	0.314556732204976	0.408976746866176	0.344194395067453	NA	NA	0.0890601263391294	0.435230382976493	75.022595581972
a4350	loss_cnaOV70	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.65902677209875	3.94674390123533	0.71228287086342	0.577547645985272	1.06209850284765	0.686958774405202	1.23328850150241	0.670637298662678	0.344436512300543	NA	NA	0.101617900603107	0.147462590740816	75.022595581972
a4351	loss_cnaOV59	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	3.51540102976688	2.72378525047603	0.791615779290851	2.0567874154468	1.48566948927225	0.510666341855299	0.384879727163678	0.532834378714085	0.344442121894116	NA	NA	0.968529198724305	0.504666132264003	75.022595581972
a4352	loss_cnaOV36	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.60691469514959	2.74307350683977	0.86384118830982	1.28816228000383	1.39080792393315	0.624071753596192	0.670599661020388	0.621107468144781	0.34444960208782	NA	NA	0.624240061947407	0.366579874765041	75.022595581972
a4353	loss_cnaOV57_(ZNRF3)	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.18819286543372	2.57713905136371	-0.388946185929984	0.576762927452974	1.08098079133894	0.374443519513805	0.674360586328941	0.359808600713638	0.34451645007586	NA	NA	0.191350559206443	0.313788032974028	75.022595581972
a4354	loss_cnaOV84	1175	AG-014699	PARP1, PARP2	6	27	1.6094379124341	NA	4.35250114819008	3.80085944006559	0.551641708124485	1.53432539237619	0.943070262249367	0.519946021651823	0.35953371485964	0.584942321061779	0.344608617787548	NA	NA	0.312129067978957	0.430760363444062	75.022595581972
a4355	PIK3CA_mut	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	4.52487355714115	3.48070605681571	1.04416750032545	0.491170925622717	0.865595103111245	1.249399073477	2.12587399997593	1.20630014723091	0.344640283807243	NA	NA	0.0565212939529938	0.035536101021542	75.022595581972
a4356	loss_cnaOV39	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	10	21	2.30258509299405	NA	1.84330922983418	1.20222293714793	0.641086292686252	1.97754920731816	1.1288914834446	0.443177370579296	0.324182220252136	0.567890095804514	0.34465672632629	NA	NA	0.472214776106037	0.359180094568864	75.022595581972
a4357	PIK3R1_mut	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.25280094284467	3.76083162273848	-0.508030679893814	1.09138022011523	1.03701775794873	0.486419273538785	0.465493757840117	0.489895834473197	0.344730626628043	NA	NA	0.829426802463112	0.376272052977138	75.022595581972
a4358	loss_cnaOV59	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.57829500942482	3.93283833622934	0.645456673195474	0.754619228224498	1.06223840707687	0.623270341044797	0.855340877960575	0.607638237231204	0.344748702122514	NA	NA	0.101624520651276	0.192596774431507	75.022595581972
a4359	ARID1A_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	8	24	2.32630161961136	NA	4.73619389711209	5.2778542037967	-0.541660306684602	0.47075488887593	0.559051721153239	1.00355289034936	1.15062067221007	0.968891224531495	0.344972583701117	NA	NA	0.0111951676537661	0.0176500784916677	75.022595581972
a4360	loss_cnaOV39	1026	17-AAG	HSP90	10	23	0	NA	0.316613530542882	-0.899286805608715	1.2159003361516	2.23782971643758	2.24463980326752	0.542167661363571	0.543339078581546	0.541690624206882	0.344994206851445	NA	NA	0.0591117549096131	0.169708533920692	75.022595581972
a4361	loss_cnaOV81_(RB1)	255	CP724714	ERBB2	4	28	2.32630161961136	NA	4.82323751763024	4.35675984221545	0.466477675414782	0.364139783666666	0.988607307621506	0.493670084326406	1.28104012892422	0.471853355542235	0.345014266586762	NA	NA	0.784512004385527	0.100671604252551	75.022595581972
a4362	loss_cnaOV52, loss_cnaOV53	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-2.5789684796492	-2.23591514693101	-0.343053332718189	1.04400555572441	0.631393894063932	0.457887182028487	0.328593397647346	0.543326972185532	0.345062941070454	NA	NA	0.66900482775468	0.519823021833938	75.022595581972
a4363	loss_cnaOV84	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	-1.38629436111989	0.693147180559945	-2.62482080555518	-2.01218808156267	-0.612632723992508	1.8916657040596	1.12595343864843	0.478319718107011	0.323858873519656	0.544101294923794	0.345098202123569	NA	NA	0.604324824579857	0.474847171515166	75.022595581972
a4364	RB1_mut	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	2.49868069139916	3.1247741525667	-0.626093461167542	0.941487616003585	0.904960111392957	0.690015762163952	0.665004457334422	0.691846472883573	0.34516965054165	NA	NA	0.234764696429022	0.369121448215616	75.022595581972
a4365	loss_cnaOV57_(ZNRF3)	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.29772391596086	2.93949954034574	-0.641775624384883	0.397930833348499	1.16049249103345	0.579163402512987	1.61278184699709	0.553020057728564	0.345312786327067	NA	NA	0.386430002132167	0.0499322828084568	75.022595581972
a4366	loss_cnaOV36	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.75929380859407	1.61251712063121	1.14677668796286	1.52396782557013	1.57760966037214	0.728589158200341	0.752494028234384	0.726907749596533	0.345425149221882	NA	NA	0.0394422068440478	0.321022434853851	75.022595581972
a4367	loss_cnaOV42	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	1.80919198385989	1.07941621307574	0.729775770784153	1.41503018730433	1.49197563462007	0.491529605109572	0.51573159168738	0.489133839621978	0.345473962386523	NA	NA	0.811428860554589	0.391465236477919	75.022595581972
a4368	gain_cnaOV95_(MECOM)	1527	GDC0941 (rescreen)	PI3K	8	23	1.38629436111989	NA	0.648703561485409	0.28961263098874	0.359090930496669	0.875976232706035	0.913340040866015	0.397021348630159	0.409932275659327	0.393162364978748	0.345626210297735	NA	NA	0.908786478172505	0.341735570151649	75.022595581972
a4369	gain_cnaOV51_(MYC)	1067	CCT007093	PPM1D	8	25	1.88706964903238	NA	4.38729174755202	4.52250760059815	-0.135215853046137	0.775874752408335	0.680686204095959	0.192257115955446	0.174275361617869	0.198646383946802	0.345635319113574	NA	NA	0.0788907887264488	0.667625058960379	75.022595581972
a4370	loss_cnaOV52, loss_cnaOV53	1016	Temsirolimus	MTOR	8	23	-1.6094379124341	NA	-1.36492958935614	-2.26046346538152	0.895533876025387	1.61644663801055	1.48912578136595	0.588843690438788	0.554013881415577	0.601382292370178	0.345658588581082	NA	NA	0.0361649433169805	0.194925095966829	75.022595581972
a4371	ARID1A_mut	1023	GW 441756	NTRK1	9	22	0.693147180559945	NA	2.59591459240083	2.17678620073893	0.419128391661899	0.620672956773521	1.42049796155401	0.334773099211189	0.675280575845736	0.295057369320951	0.345699207416387	NA	NA	0.843039211715065	0.262574488974244	75.022595581972
a4372	loss_cnaOV84	173	FH535	unknown 	4	14	3.46573590279973	NA	2.8774575771017	2.38807461950791	0.489382957593791	1.73752059109961	1.36801693183243	0.338786680971632	0.281655918266891	0.357731652442542	0.345729222364656	NA	NA	0.114972059950399	0.630222801271935	75.022595581972
a4373	SMAD4_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	0.159212324161022	1.09158796453742	-0.932375640376397	0.701807073967377	1.57945900495443	0.606768857729402	1.3285355405519	0.590313289203285	0.345811874470379	NA	NA	0.789112782646906	0.127002976495235	75.022595581972
a4374	gain_cnaOV50	304	SB52334	ALK5	4	28	2.99573227355399	NA	4.76782733851585	4.30932806748992	0.458499271025932	0.400459391461245	1.10900583751584	0.432673321165735	1.14493324617236	0.413432693963961	0.345968653771605	NA	NA	0.347435076943284	0.140502762415578	75.022595581972
a4375	loss_cnaOV59	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	3.20752198468018	2.32995633371714	0.877565650963035	1.66178065329812	1.41252002971065	0.609678935258849	0.528087536234903	0.621276606706103	0.345993289620716	NA	NA	0.235891223436907	0.37660589486272	75.022595581972
a4376	loss_cnaOV1	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.43908419465612	5.75858805558837	0.680496139067754	0.469372602614981	1.31994613093178	0.531249519753987	1.44979944563564	0.515548417561086	0.346042207910476	NA	NA	0.567413727483473	0.109457807665597	75.022595581972
a4377	gain_cnaOV18_(CCNE1)	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	4.05675921638996	3.4928883693376	0.563870847052363	0.540291854620866	0.935570568715159	0.623133440115361	1.04364121396582	0.60270263506337	0.346083230095079	NA	NA	0.139485819013531	0.13063644830895	75.022595581972
a4378	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	3.32131906133059	2.34844510685548	0.972873954475107	2.0160788083775	1.39063598412389	0.675230024065528	0.482557502431196	0.699589227937332	0.346188472283797	NA	NA	0.235896984783929	0.493370816896261	75.0282680977805
a4379	NF1_mut	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.54875936078953	2.93529921515325	0.613460145636286	0.826020132640635	1.09430643931599	0.573055303435401	0.742669726069709	0.56059264900217	0.346281016243193	NA	NA	0.430336037187902	0.24545106950268	75.0311866065614
a4380	loss_cnaOV58	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	1.58188759713731	0.897194442903025	0.684693154234284	1.34742307302169	1.56843769870143	0.444374558114128	0.508150088820146	0.436544693360257	0.346585901375389	NA	NA	0.789123055956989	0.347662648386129	75.0774868691635
a4381	gain_cnaOV94	1527	GDC0941 (rescreen)	PI3K	7	24	1.38629436111989	NA	0.658448340247761	0.301732525953749	0.356715814294013	0.927246190667557	0.90025539135218	0.393767059823948	0.384704534657835	0.396238464907415	0.346666903955667	NA	NA	0.908792799295972	0.389494905445455	75.0774868691635
a4382	loss_cnaOV52, loss_cnaOV53	1033	Vismodegib	SMO	8	23	2.30258509299405	NA	5.24427752507057	4.79500099298393	0.44927653208664	0.840483216780942	0.844151986257888	0.532780319692536	0.534545512767492	0.532222324179175	0.346760752440711	NA	NA	0.150469443970418	0.217171350289985	75.0774868691635
a4383	loss_cnaOV1	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	2.30985040070339	2.83841296755304	-0.528562566849651	1.49933133519217	1.20697344323745	0.430204761278008	0.352532195148116	0.437923940921097	0.346840026541706	NA	NA	0.0919184846030842	0.607870658491468	75.0774868691635
a4384	SMARCA4_mut	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.514355406326436	-0.0167137562386394	-0.497641650087796	1.86764658400716	0.860137037478091	0.517968397254127	0.266453864638604	0.578560890188933	0.347104160499351	NA	NA	0.545292551758085	0.691109341956147	75.0774868691635
a4385	PIK3CA_mut	1527	GDC0941 (rescreen)	PI3K	7	24	1.38629436111989	NA	0.17000865553284	0.444194100662267	-0.274185445129428	1.13361804925977	0.843670195030598	0.300885971744043	0.241867571981997	0.324991266426668	0.34715959764424	NA	NA	0.908795782781422	0.56899874525999	75.0774868691635
a4386	SMAD4_mut	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	2.69775817558355	3.78180050032667	-1.08404232474312	4.29971490570345	1.5605835802142	0.539288912169386	0.252119581999534	0.694639068670919	0.34722803020743	NA	NA	0.745167768155536	0.650558293909455	75.0774868691635
a4387	loss_cnaOV1	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	4.12626790123305	3.50473319575504	0.621534705478015	1.01050476953993	0.898385018763754	0.685992375140756	0.615073500109248	0.691835563256936	0.34728523615908	NA	NA	0.139514355881093	0.399676485221455	75.0774868691635
a4388	loss_cnaOV33_(ZFHX3)	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.77059325550636	4.34603722796414	0.424556027542214	1.3448555509145	0.785422521006083	0.496151741406648	0.315688943138553	0.540544759269674	0.347374715845264	NA	NA	0.868374079836282	0.577330437583127	75.0774868691635
a4389	gain_cnaOV18_(CCNE1)	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	3.75372741179135	2.42059335317117	1.33313405862018	1.58942480817559	2.37571870474738	0.577321938633805	0.838752517113664	0.561149792673766	0.347539027459097	NA	NA	0.381685100224043	0.202190726799746	75.0774868691635
a4390	loss_cnaOV35	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	2.9873624174686	2.66579020879164	0.321572208676961	0.837851951255338	0.50552988246603	0.572881128238939	0.383805525779531	0.63610919914031	0.347639371986826	NA	NA	0.132187952492574	0.447499904140803	75.0774868691635
a4391	loss_cnaOV38	1377	Afatinib (rescreen)	ERBB2, EGFR	8	25	2.30258509299405	NA	3.08315285784003	2.51813617201886	0.565016685821162	1.50200833287626	1.7518149879113	0.332632526316255	0.376174135292037	0.322532167905947	0.347945213252275	NA	NA	0.637096801835795	0.389849647675113	75.0774868691635
a4392	loss_cnaOV85	1262	UNC1215	LMBL3	7	26	0	NA	2.98831629751379	2.72443866027723	0.263877637236562	0.662348508889911	0.433437030150906	0.542704349255481	0.398396967298708	0.608802706923056	0.347992065549627	NA	NA	0.106735780832057	0.349585689777162	75.0774868691635
a4393	gain_cnaOV4_(KRAS)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	1.27151379996701	0.75661952870351	0.514894271263496	0.960058017485808	1.29730530290804	0.416166292979507	0.536315787052012	0.396895218195216	0.348121227268811	NA	NA	0.843494745668735	0.269393461148061	75.0774868691635
a4394	gain_cnaOV48_(SOX17)	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-4.01841432258756	-3.2398423713367	-0.778571951250866	2.47640699787027	1.76478010053018	0.427129873149634	0.314395796781564	0.441172218010032	0.348136290306916	NA	NA	0.135891969291067	0.644148487091931	75.0774868691635
a4395	RB1_mut	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	2.97895669962092	3.61946431591625	-0.640507616295326	0.490812184461475	0.926634933409051	0.707841713327461	1.30499534561901	0.691218939846057	0.348166841921863	NA	NA	0.139535202731026	0.131099142292318	75.0774868691635
a4396	gain_cnaOV49	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	4.03586767086647	3.5059156776987	0.529951993167765	1.38748340134583	0.9158271831291	0.555185632622265	0.381951951752159	0.578659383484428	0.348221814166071	NA	NA	0.72609508368035	0.578957539278164	75.0774868691635
a4397	loss_cnaOV40	279	BIX02189	MAP2K5 (MEK5)	7	25	2.99573227355399	NA	4.16814199506472	4.50483450874488	-0.33669251368016	0.701306917004936	0.736877103642247	0.461284702569728	0.480092960038194	0.456918137388109	0.348248553570875	NA	NA	0.520602444976101	0.292805022521516	75.0774868691635
a4398	loss_cnaOV59	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	3.91899009144888	3.49085589859312	0.428134192855766	0.99936036939101	0.888042585635923	0.475813407647636	0.428408215863775	0.482109979612274	0.348275943112517	NA	NA	0.660401303637008	0.465552311866588	75.0774868691635
a4399	gain_cnaOV95_(MECOM)	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.83639480132524	3.57569203031227	0.260702771012967	0.415137236351314	0.971792346746189	0.286404579268389	0.627991777621089	0.268270039258765	0.348329793415184	NA	NA	0.0566034994669441	0.41592669376191	75.0774868691635
a4400	gain_cnaOV94	208	SB-715992	KIF11	7	25	-2.05572501506252	NA	-0.536016823770641	-1.53618607980251	1.00016925603187	0.933637162248222	2.00162564797306	0.544057390723089	1.07126118847223	0.499678477363978	0.348439704894702	NA	NA	0.0716680531773604	0.0741295184966396	75.0774868691635
a4401	loss_cnaOV54	1020	Lenalidomide	TNFA	10	21	1.6094379124341	NA	4.69331743291326	4.26021412261121	0.43310331030205	0.554014477862783	0.822759014374424	0.577674098098079	0.781754498497636	0.526403603892879	0.34850520872295	NA	NA	0.0412875447089844	0.0964573780023391	75.0774868691635
a4402	loss_cnaOV52, loss_cnaOV53	255	CP724714	ERBB2	8	24	2.32630161961136	NA	4.6703056072273	4.3299908664473	0.340314740779997	0.991140450835594	0.931952062273826	0.359705019090525	0.343356726580062	0.365163353949428	0.348538457887658	NA	NA	0.784559634312923	0.410908770416132	75.0774868691635
a4403	loss_cnaOV40	281	CH5424802	ALK	7	25	1.63315443905142	NA	4.16011712298007	3.86250244453934	0.29761467844073	0.651877241302501	0.74163988693897	0.410742363880535	0.456550190103389	0.401292707797983	0.348640590602441	NA	NA	0.955386528758929	0.323385050319497	75.0774868691635
a4404	gain_cnaOV26	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.31316403224162	3.8877203061248	0.425443726116816	0.28259405279013	0.746012010548756	0.587304833435141	1.50549426612588	0.570290719319472	0.348779838915949	NA	NA	0.955386925362209	0.0964259590225271	75.0774868691635
a4405	loss_cnaOV38	1033	Vismodegib	SMO	8	23	2.30258509299405	NA	5.24327839909926	4.79534851506091	0.447929884038347	0.98528954013849	0.792966924858033	0.531091043108896	0.454617516771148	0.564878395298191	0.348841041409196	NA	NA	0.150523809677397	0.271489087398296	75.0774868691635
a4406	loss_cnaOV54	346	THZ-2-102-1	CDK7	10	22	0.916290731874155	2.99573227355399	-0.686490528731504	-1.22893080512648	0.542440276394981	1.81773173493693	2.0352855462947	0.274995773534493	0.298416023645976	0.266518021209609	0.348848658380622	NA	NA	0.439496474917128	0.460360029913973	75.0774868691635
a4407	PIK3CA_mut	226	GSK1070916	AURKB	6	26	0.940007258491471	2.32630161961136	1.95309270688668	2.3972492294727	-0.444156522586014	0.511318157996498	1.56644133764404	0.307350364382431	0.868650009079191	0.283544944781676	0.348860648447631	NA	NA	0.819344701629253	0.242607330077604	75.0774868691635
a4408	PIK3CA_mut	1049	PD-173074	FGFR1, FGFR3	7	26	0.693147180559945	NA	2.38997833099024	3.14711457508395	-0.757136244093711	0.837901384207643	0.990391273072586	0.7864194357797	0.903610208031453	0.764481942318387	0.348881736005339	NA	NA	0.0850944608238014	0.0663594277166248	75.0774868691635
a4409	loss_cnaOV70	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	2.96484817665175	2.22193094412596	0.742917232525796	1.88733704876761	1.36230758550373	0.528830595825929	0.393632516783849	0.545337367589489	0.348966336999745	NA	NA	0.52608477569074	0.569036729862116	75.0774868691635
a4410	loss_cnaOV58	1008	Methotrexate	Dihydrofolate reductase (DHFR)	5	26	-1.6094379124341	NA	1.1063154016896	0.461742837567502	0.644572564122103	1.43114111769667	1.15618609447742	0.538099361256056	0.450390640134426	0.557498976333424	0.348972840492181	NA	NA	0.426640001923625	0.385621003364519	75.0774868691635
a4411	loss_cnaOV85	1259	BMN-673	PARP1	7	26	2.30258509299405	NA	2.51549326556684	1.73480462922555	0.780688636341285	1.56509338246772	1.2948267745336	0.577705261703526	0.498812815316076	0.602929018534154	0.34907637466959	NA	NA	0.0328311908642604	0.258440929130636	75.0774868691635
a4412	loss_cnaOV58	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.25804448975268	2.55762964857416	-0.29958515882148	0.646925227293291	0.621071510393397	0.479658194222769	0.46309085839013	0.482368219775075	0.349105872076223	NA	NA	0.856831801745325	0.378995232392633	75.0774868691635
a4413	loss_cnaOV34	1028	VX-702	p38	5	26	0.693147180559945	NA	3.02013597647827	3.38597561493374	-0.365839638455465	1.39815727564516	0.822042777080752	0.396300822790376	0.261658430584395	0.445037227569396	0.349216290267586	NA	NA	0.514187242501048	0.597829016854922	75.0842148378396
a4414	loss_cnaOV57_(ZNRF3)	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-2.4151270243657	-1.97220697485783	-0.44292004950787	1.41131731625111	1.58328330808784	0.282768565626037	0.313834489528124	0.279747817238592	0.349410744955906	NA	NA	0.0362079435261919	0.593888563087813	75.1013911495801
a4415	loss_cnaOV40	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	2.84176909521353	2.39894334271579	0.442825752497738	0.967245075248057	0.706379200793206	0.583465485705531	0.45782166674167	0.626895231343846	0.349726216543612	NA	NA	0.74521709594382	0.441069570063467	75.1013911495801
a4416	loss_cnaOV1	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	4.93967974353378	3.79146745906602	1.14821228446776	0.143048221623188	1.7547083510677	0.677996558928335	8.02674980114279	0.654360756742904	0.349752172746162	NA	NA	0.1436697003125	0.0022013450329222	75.1013911495801
a4417	ARID1A_mut	329	QL-XI-92	DDR1	8	24	2.32630161961136	NA	4.04446094061389	4.69674558824904	-0.65228464763515	0.722747217491984	1.04971687521973	0.66343136863932	0.90250731078378	0.621391027460249	0.349787299996197	NA	NA	0.187489805686487	0.0664827205448152	75.1013911495801
a4418	loss_cnaOV87, loss_cnaOV88	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.91278835888519	3.2103359917342	0.702452367150991	1.02175047608283	1.02881565901154	0.683089407574171	0.687498937944266	0.682777678389818	0.349832445645471	NA	NA	0.0891704388049923	0.356260316678842	75.1013911495801
a4419	gain_cnaOV50	341	EX-527	SIRT1	4	27	2.99573227355399	NA	5.59689628558163	5.79944909271325	-0.202552807131619	0.798132869694388	0.531594522641283	0.358482452845737	0.253783317067468	0.381028770058078	0.349884337973087	NA	NA	0.10751303013474	0.652926630808871	75.1013911495801
a4420	gain_cnaOV50	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	1.32310550698148	1.78281254724186	-0.459707040260371	1.74509722335172	1.5876338589031	0.286486110418599	0.263427752969222	0.289554822531929	0.349892633522312	NA	NA	0.0394965096261448	0.646575641359768	75.1013911495801
a4421	KRAS_mut	333	T0901317	LXR	7	25	2.32630161961136	NA	4.1914902388415	4.91067297492817	-0.719182736086674	1.85101156379446	0.786360026391341	0.662078644324676	0.388534977389549	0.914571839806065	0.349929390305262	NA	NA	0.00477300828128283	0.351144311428477	75.1013911495801
a4422	loss_cnaOV55	1039	SL 0101-1	RSK, AURKB, PIM3	8	25	2.30258509299405	NA	5.16796187741199	4.86396742394779	0.303994453464204	0.757084960681726	0.83051499903355	0.373222409097156	0.401532812368204	0.366031262310681	0.350122181049052	NA	NA	0.945507956337051	0.352324307195119	75.1257747115023
a4423	ARID1A_mut	151	QS11	ARFGAP	5	14	2.32630161961136	NA	3.57782999752748	3.83426143303254	-0.256431435505067	1.6836558900732	1.40268335191871	0.174014378078391	0.152306321628417	0.182814913397452	0.350256096001063	NA	NA	0.0607375506999565	0.770578169230244	75.1375171153762
a4424	SMARCA4_mut	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	1.54183315187874	2.46284169532758	-0.921008543448834	0.655042951778219	1.32158331003105	0.714500802849719	1.40602771306616	0.696897831909815	0.350342146541664	NA	NA	0.107108578939992	0.110830953662261	75.138988579001
a4425	PIK3CA_mut	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	7.48077819909647	6.41795018289895	1.06282801619752	1.34588524395389	1.48492272890572	0.731267555472668	0.789686952117244	0.715746345253092	0.350654902880039	NA	NA	0.329238647163088	0.179699522732524	75.1408988699415
a4426	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	2.96229515021833	2.22220448267239	0.74009066754594	1.55477355777737	1.39323247864056	0.52676629416673	0.476011869280785	0.531204001408351	0.350672673847673	NA	NA	0.526130997113651	0.500642711269262	75.1408988699415
a4427	loss_cnaOV57_(ZNRF3)	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.49059510868179	0.838476912322503	0.652118196359285	0.946264670096017	1.29260933858397	0.517528377821247	0.689149893225027	0.504497512816726	0.350881883443984	NA	NA	0.957063416886776	0.279458551474394	75.1408988699415
a4428	loss_cnaOV41	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.78643314008781	-3.82520268607202	1.0387695459842	2.49211943143623	1.59049631931657	0.608888359252571	0.41682173529924	0.653110311145238	0.350885995414068	NA	NA	0.24093038986555	0.471415388843937	75.1408988699415
a4429	loss_cnaOV42	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.78643314008781	-3.82520268607202	1.0387695459842	2.49211943143623	1.59049631931657	0.608888359252571	0.41682173529924	0.653110311145238	0.350885995414068	NA	NA	0.24093038986555	0.471415388843937	75.1408988699415
a4430	loss_cnaOV41	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	3.01929218002599	2.26479605054763	0.754496129478357	1.85308645439919	1.18120625973055	0.585901972163959	0.40715646465776	0.638750534263568	0.350943789238711	NA	NA	0.10712097008094	0.422904772836035	75.1408988699415
a4431	loss_cnaOV54	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	11	22	0.693147180559945	NA	2.58471203746525	2.90444333238384	-0.319731294918589	0.90615526597719	0.980954595205354	0.333935418385868	0.352843830327238	0.325938933852138	0.351047756942661	NA	NA	0.965901673426808	0.363019017745994	75.1408988699415
a4432	loss_cnaOV36	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	3.92863082884233	2.44847003618728	1.48016079265506	1.45274646985148	2.36046946220632	0.640464665565678	1.01887068622949	0.62706203844364	0.351055919928262	NA	NA	0.381790444586634	0.209496780571648	75.1408988699415
a4433	ARID1A_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	-1.38629436111989	0.693147180559945	-1.73667622731903	-2.26866320790216	0.531986980583131	0.878699353263828	1.39357515465603	0.415395332378268	0.605425483252181	0.381742584033395	0.351113160833279	NA	NA	0.604458784055898	0.205454260398743	75.1408988699415
a4434	loss_cnaOV54	1028	VX-702	p38	10	21	0.693147180559945	NA	3.59359169755601	3.2000061378623	0.393585559693708	0.967397049264267	0.888886692679168	0.430631034852958	0.40685007256642	0.442784848659859	0.351157024096609	NA	NA	0.514240600522595	0.292856767893459	75.1408988699415
a4435	gain_cnaOV72_(ASXL1)	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	0.306235046114442	1.47205172372037	-1.16581667760593	1.55480712378785	2.40010623265103	0.505694486421534	0.74981434016442	0.485735448600636	0.351451522399985	NA	NA	0.359270828075077	0.199765879856373	75.1408988699415
a4436	loss_cnaOV81_(RB1)	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	6.03351806908083	5.46806404587025	0.565454023210577	0.753943976851347	0.990554832673074	0.583245448590527	0.749994748379118	0.570845756902386	0.351492082426051	NA	NA	0.29997095186317	0.241191458319058	75.1408988699415
a4437	loss_cnaOV82	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.04034884073705	4.06002587023373	0.980322970503318	0.873434468148867	1.47220175161776	0.680755987723512	1.12237724323038	0.665889012444164	0.351514608497536	NA	NA	0.0908088936706367	0.176897364847465	75.1408988699415
a4438	loss_cnaOV44	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.79902403422411	2.09902473792978	0.699999296294338	0.578953869518857	1.33340003217426	0.540309781622133	1.20907611667934	0.524973210892239	0.351529349641355	NA	NA	0.683795437108353	0.157718638410118	75.1408988699415
a4439	loss_cnaOV41	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.41945577807977	2.71264633901692	0.706809439062852	2.30732861215792	1.40477242180157	0.455703403657603	0.306332368670196	0.503148715118136	0.351538952582696	NA	NA	0.968543018076882	0.539245087074443	75.1408988699415
a4440	KRAS_mut	1039	SL 0101-1	RSK, AURKB, PIM3	7	26	2.30258509299405	NA	4.68410588661403	5.00592843891125	-0.32182255229722	0.755812855226197	0.827713056501117	0.395217380089476	0.425796610988981	0.388809321986073	0.352010976776273	NA	NA	0.945514242902516	0.349915006439599	75.1659667863047
a4441	loss_cnaOV39	1241	CHIR-99021	GSK3B	9	23	2.30258509299405	NA	3.97246475470339	3.56757720590573	0.404887548797662	0.775652537477247	1.1269486410492	0.387495752292828	0.521996034609168	0.35927772930336	0.352254128038213	NA	NA	0.829507548216059	0.25929282938394	75.1659667863047
a4442	loss_cnaOV85	173	FH535	unknown 	5	13	3.46573590279973	NA	2.78938453210556	2.38430402469152	0.405080507414044	1.51756965561578	1.42380144539842	0.27978787454994	0.266927126484798	0.284506318435918	0.352266816093589	NA	NA	0.115245966856782	0.622035915832913	75.1659667863047
a4443	loss_cnaOV84	253	XMD14-99	EPHB3, CAMK1	6	26	2.32630161961136	NA	5.14143951804842	4.7951310452247	0.346308472823723	0.518347444686825	0.626411353723449	0.56796817312846	0.668101051473217	0.552845140442031	0.352489321754887	NA	NA	0.0477959710622659	0.191610852248342	75.1659667863047
a4444	gain_cnaOV18_(CCNE1)	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.7415773652876	4.15866889055141	0.582908474736192	0.670104742964556	0.993105141511135	0.603065371552629	0.869876658621149	0.586955449499761	0.352502528235103	NA	NA	0.205812645939104	0.187486659969002	75.1659667863047
a4445	loss_cnaOV87, loss_cnaOV88	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.31875073407928	5.910069609747	0.40868112433228	1.26319599004803	0.64070918242412	0.585643745707881	0.323529466173133	0.637857448501108	0.352552019840718	NA	NA	0.90792085526936	0.633220439369225	75.1659667863047
a4446	loss_cnaOV85	1495	AZD-2281	PARP1, PARP2	7	26	2.30258509299405	NA	3.9370791470865	3.46004790564403	0.477031241442472	1.46282889588263	0.704481142059547	0.528599356899396	0.326101872054315	0.677138411466734	0.352693447092458	NA	NA	0.13964114291837	0.43113299308929	75.1659667863047
a4447	loss_cnaOV39	310	YM201636	FYV1	9	23	1.63315443905142	NA	2.10355432452645	2.45605832042091	-0.352503995894453	1.12158495814751	0.741369068982305	0.410189439905909	0.314290944554635	0.475477074297614	0.352856977442721	NA	NA	0.647693972311144	0.402438164469678	75.1659667863047
a4448	gain_cnaOV19	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.13442640092825	4.43756981223811	-0.303143411309865	0.586596379910473	0.633677018113206	0.480685852274084	0.516783638105866	0.478387889484274	0.352879264413939	NA	NA	0.267017371740296	0.470774877256874	75.1659667863047
a4449	loss_cnaOV55	1377	Afatinib (rescreen)	ERBB2, EGFR	8	25	2.30258509299405	NA	2.11184567537431	2.82895447040789	-0.717108795033578	2.00986778361654	1.5809535156983	0.424988090735064	0.356794014451646	0.453592586950181	0.352881074949439	NA	NA	0.637198369630586	0.378375103060777	75.1659667863047
a4450	loss_cnaOV35	1024	CEP-701	FLT3, JAK2, NTRK1, RET	5	26	0.693147180559945	NA	0.639120116551924	-0.311026911538316	0.95014702809024	1.72342000913957	1.55744567156197	0.60083611600807	0.551314840869586	0.610067526231801	0.352883331582803	NA	NA	0.0976399037451777	0.300568384626935	75.1659667863047
a4451	SMAD4_mut	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.67459899601996	4.29236426341864	0.382234732601321	0.274953938129187	0.597191841731946	0.658188391160263	1.39017733370936	0.640053506914601	0.352891529159295	NA	NA	0.249804550587476	0.114045557813622	75.1659667863047
a4452	ARID1A_mut	173	FH535	unknown 	5	13	3.46573590279973	NA	2.58178549533815	2.4641498080636	0.117635687274543	1.94070242997951	1.25883115479181	0.0806012562757455	0.0606150048855174	0.0934483443841986	0.352947932646271	NA	NA	0.115274124909681	0.90452078689958	75.1659667863047
a4453	loss_cnaOV58	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	5.97935253091619	5.45715195948553	0.52220057143066	0.886183605047107	0.981071571654113	0.538930664284107	0.589269050405081	0.532275714146131	0.352991716561464	NA	NA	0.300015795019517	0.279340355798141	75.1659667863047
a4454	loss_cnaOV43_(NF1)	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.5348959279	5.12707776445036	0.407818163449643	0.747809358206796	0.764762665822976	0.534826657036239	0.545350441224175	0.533261077815275	0.35302621667044	NA	NA	0.329430338056956	0.309442956144359	75.1659667863047
a4455	gain_cnaOV18_(CCNE1)	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	2.42684485225158	1.5774315747395	0.849413277512082	1.61692259016973	1.45047093161105	0.578632931972558	0.525327113787754	0.585612065019899	0.353122547531705	NA	NA	0.32225866839491	0.379906785444954	75.1659667863047
a4456	TP53_mut	219	AT-7519	CDK9	22	10	2.32630161961136	NA	1.67718289645241	1.10286228719989	0.574320609252522	1.61716237891073	1.86894497840244	0.338507682718207	0.355140965893213	0.307296691924793	0.353182582181205	NA	NA	0.311944220833855	0.414099795683559	75.1659667863047
a4457	loss_cnaOV56	1026	17-AAG	HSP90	3	30	0	NA	-1.34064053630475	-0.449851320488579	-0.890789215816166	2.17130413798364	2.30910323785392	0.387221865413518	0.41025538533878	0.385772797514271	0.353229341807991	NA	NA	0.0592331828188065	0.558067738454902	75.1659667863047
a4458	loss_cnaOV56	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.77020125296297	2.94357198588459	0.826629267078387	1.51926750802514	1.14625860491051	0.703042434998375	0.544097246016208	0.721154252222971	0.353315400931583	NA	NA	0.0858317193991523	0.447414777016818	75.1659667863047
a4459	gain_cnaOV48_(SOX17)	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.74956169836288	-4.12488085621116	-0.624680842151723	0.950005590456665	1.36071061673691	0.46713480292016	0.657554911704721	0.459084271459391	0.353397336401663	NA	NA	0.213812819379033	0.378658009641721	75.1659667863047
a4460	gain_cnaOV96	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	-0.427799932335975	0.264445044572971	-0.692244976908946	1.05728050536682	1.36400138898138	0.526388925699562	0.654741077126712	0.507510463333111	0.353413668899194	NA	NA	0.867777154808978	0.317624477977031	75.1659667863047
a4461	ARID1A_mut	301	PHA-793887	CDK-pan	8	24	2.32630161961136	NA	2.50796896784647	3.17712968374514	-0.669160715898677	1.25758439700226	1.70098705354811	0.416016244529529	0.532100046321961	0.393395537316328	0.353413963863962	NA	NA	0.660686568115344	0.25255995714209	75.1659667863047
a4462	loss_cnaOV82	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.46428283441074	4.82929013271393	-0.365007298303182	0.838603725986226	0.646049376955728	0.552510019146655	0.435255993972506	0.564983593085633	0.353521743610949	NA	NA	0.760069473245787	0.532907309192724	75.1659667863047
a4463	loss_cnaOV52, loss_cnaOV53	1003	Camptothecin	TOP1	8	23	-2.30258509299405	NA	-3.0572363529303	-3.91166583742841	0.854429484498101	0.933316473286694	1.87970147049137	0.50254662411515	0.915476699440662	0.454555948330851	0.353685873959974	NA	NA	0.241014323769205	0.107908817138141	75.1659667863047
a4464	gain_cnaOV48_(SOX17)	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.20139916914038	4.47785149388306	-0.276452324742682	0.178196419611859	0.572334964674071	0.498256750412342	1.55139101753469	0.483025399121148	0.353744376339002	NA	NA	0.360719549728326	0.0990190556925231	75.1659667863047
a4465	loss_cnaOV102	326	GSK690693	AKT	3	29	2.32630161961136	NA	5.03699862536196	4.06037244423805	0.97662618112391	1.28942748263682	1.45045290472137	0.67808168263002	0.757410706902848	0.673324985557888	0.353780508533571	NA	NA	0.0908527251290068	0.318708023417009	75.1659667863047
a4466	loss_cnaOV52, loss_cnaOV53	1091	BMS-536924	IGF1R	8	24	1.38629436111989	NA	2.10300533706717	2.49037604432961	-0.387370707262441	1.05973663861066	0.892834305423014	0.41454478832773	0.365534882110232	0.433866289533879	0.353795162036505	NA	NA	0.732569499152223	0.373341999218758	75.1659667863047
a4467	gain_cnaOV72_(ASXL1)	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	1.99522886735007	1.48436520810012	0.510863659249942	0.834689017863182	1.07855515282776	0.487165282231477	0.61204071015306	0.473655573301519	0.354118480190432	NA	NA	0.281308867104643	0.335555276421458	75.2160682212331
a4468	PIK3R1_mut	152	CP466722	ATM	5	27	2.77258872223978	NA	2.86988474620289	2.60562630331144	0.264258442891448	0.877364354468793	0.804509191998285	0.324402793218267	0.301195782055045	0.328471626576532	0.354189527128363	NA	NA	0.552487022181644	0.556886351431228	75.2160682212331
a4469	ARID1A_mut	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-3.56923737649215	-2.18001813322994	-1.38921924326221	0.972683962795863	2.1309670151336	0.722693519165702	1.42823290647156	0.651919637139535	0.35427988733738	NA	NA	0.337568219709069	0.0710234155845165	75.2184222922861
a4470	loss_cnaOV83	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	3.11811811589891	2.31401017419652	0.804107941702393	1.44145135950455	1.43863969685064	0.558790558903081	0.557846046209134	0.558936294794786	0.354710721580786	NA	NA	0.236144349310485	0.298477520818457	75.2477898427527
a4471	loss_cnaOV54	1129	PF-4708671	RPS6KB1 (p70S6KA)	11	21	2.30258509299405	NA	4.52801388493983	4.02365910055957	0.504354784380259	0.797975168254951	1.01775632211918	0.530809574281316	0.632043206912322	0.495555540573885	0.354741242932111	NA	NA	0.0463439241700487	0.135961724100171	75.2477898427527
a4472	loss_cnaOV84	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	3.20396517154248	2.89423743205838	0.309727739484103	0.67452769978479	0.565442494083108	0.522378778034805	0.459177198479651	0.547761695884462	0.354862992843158	NA	NA	0.847136864920274	0.393247408458557	75.2477898427527
a4473	loss_cnaOV40	1018	ABT-888	PARP1, PARP2	7	24	1.6094379124341	NA	4.61699488193736	4.20700693646557	0.409987945471792	1.01069617191152	0.71922789987136	0.520010585839687	0.405649053460236	0.57003898979047	0.354949831977144	NA	NA	0.22105661401207	0.346280238250658	75.2477898427527
a4474	gain_cnaOV4_(KRAS)	281	CH5424802	ALK	8	24	1.63315443905142	NA	4.13973945393464	3.85689438928612	0.282845064648522	0.604911550819469	0.757379201378713	0.390304291363073	0.467580862467172	0.373452379116878	0.354967368901976	NA	NA	0.955404330333398	0.300768787424329	75.2477898427527
a4475	loss_cnaOV82	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	5.10439109255592	4.47066488482363	0.633726207732283	1.11605068701795	0.968098432471633	0.647770401321917	0.56782923491188	0.654609269549512	0.355034948313491	NA	NA	0.321526614983193	0.431193265162549	75.2477898427527
a4476	loss_cnaOV38	326	GSK690693	AKT	8	24	2.32630161961136	NA	4.70982942726873	3.96596505586831	0.743864371400417	0.771410637467815	1.57893252964035	0.519515606133548	0.964291047168056	0.47111852940914	0.355035965711367	NA	NA	0.0908768508086005	0.0902118568713619	75.2477898427527
a4477	gain_cnaOV96	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	2.8370321545713	2.34101220058192	0.496019953989375	0.743035897881224	0.853349899504943	0.594076804596444	0.667558533045015	0.581262099259791	0.355112659059189	NA	NA	0.616319489712208	0.299650064645458	75.2477898427527
a4478	loss_cnaOV21, loss_cnaOV22	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.65727895123164	0.762530305004824	0.894748646226813	0.563046127361097	1.36744808722182	0.672586021998445	1.58912139298489	0.654320010088741	0.355227085118442	NA	NA	0.159920304544188	0.0815105478178417	75.2477898427527
a4479	gain_cnaOV18_(CCNE1)	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.57858543808129	4.2401846389469	0.338400799134385	1.01866527092622	0.791168803489004	0.413873273072668	0.332200192538904	0.427722627133501	0.355418314822522	NA	NA	0.312615814187719	0.56304482121652	75.2477898427527
a4480	loss_cnaOV81_(RB1)	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-2.19742947202479	-3.43494789103985	1.23751841901506	2.26480121223901	1.75951853861142	0.687919998042038	0.546413703916927	0.703327866037541	0.355480760339727	NA	NA	0.136072757432275	0.445902401028244	75.2477898427527
a4481	loss_cnaOV83	1023	GW 441756	NTRK1	5	26	0.693147180559945	NA	1.79931941743726	2.39445887156452	-0.595139454127258	1.14149794901862	1.26302190244867	0.47727064674811	0.521367081420444	0.471202797808525	0.355511484872442	NA	NA	0.843139063139123	0.334312719881651	75.2477898427527
a4482	loss_cnaOV56	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.65673190384634	0.762585009743354	0.894146894102988	0.562180468691069	1.36750966487605	0.672115699217849	1.59049796977978	0.653850511677394	0.355623472873217	NA	NA	0.159929940231543	0.0813273462393772	75.2477898427527
a4483	loss_cnaOV39	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	-0.346196888384281	0.284747170083719	-0.630944058468	2.05531141756261	0.982537032734344	0.479395221588088	0.306982218400867	0.642158043358548	0.355663410389343	NA	NA	0.867810962321604	0.540386484786118	75.2477898427527
a4484	loss_cnaOV38	1038	NU-7441	PRKDC (DNAPK)	8	25	0.693147180559945	NA	2.89274800735195	2.4232195056641	0.469528501687856	1.07286105327484	1.00776924793291	0.459048631559864	0.43764148232863	0.465908741163645	0.355697793492183	NA	NA	0.391240292875607	0.297204742522319	75.2477898427527
a4485	SMAD4_mut	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	1.79130070116044	2.41087036513549	-0.619569663975053	1.26820679570632	1.21637457791864	0.506769574733865	0.488539933765286	0.509357623237414	0.355711799049032	NA	NA	0.381789881243425	0.496458839510848	75.2477898427527
a4486	loss_cnaOV55	263	FR-180204	ERK	7	25	2.99573227355399	NA	4.56491821265915	4.88088240296958	-0.315964190310437	0.697888156397156	0.751684804278852	0.426265567296731	0.452743304803452	0.420341329918948	0.355772695092151	NA	NA	0.763241368018046	0.321921644745217	75.2477898427527
a4487	gain_cnaOV18_(CCNE1)	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	3.58718782582793	2.62928032648276	0.957907499345173	2.299814473189	1.57517664348329	0.576386058852953	0.416515119159549	0.608127033439813	0.355852216194173	NA	NA	0.317213552742371	0.472384369367171	75.2477898427527
a4488	loss_cnaOV1	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.52785375864602	3.83848834983245	0.689365408813569	0.288314348113369	1.09743042213532	0.647922651368591	2.39102012551419	0.628163202795345	0.355925021639732	NA	NA	0.312459446626143	0.0235896078835238	75.2477898427527
a4489	SMARCA4_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-3.31781537044768	-2.19629851494642	-1.12151685550126	0.684840848545999	1.63864417912515	0.703400823192181	1.63763136775847	0.684417562878125	0.356158278290861	NA	NA	0.121345635439905	0.074971727187262	75.2754239063816
a4490	loss_cnaOV59	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.79461824498854	-3.82399007793858	1.02937183295004	2.4816418077271	1.5932030328186	0.603137885156492	0.414794685415468	0.646102104845314	0.356296262176713	NA	NA	0.241091768935747	0.473471002257587	75.2754239063816
a4491	loss_cnaOV59	341	EX-527	SIRT1	4	27	2.99573227355399	NA	6.0718617671998	5.72908383617722	0.342777931022571	0.544957749712829	0.558194691744522	0.615577122406404	0.628999094339335	0.61408310772589	0.356326853920381	NA	NA	0.107653890897287	0.306929774636817	75.2754239063816
a4492	gain_cnaOV94	1028	VX-702	p38	7	24	0.693147180559945	NA	3.6566109395529	3.23082372057493	0.425787218977971	0.752875686585405	0.953051407479388	0.465221802879281	0.565547840851506	0.446762069324345	0.356373072077958	NA	NA	0.514382018898329	0.239963361465317	75.2754239063816
a4493	SMARCA4_mut	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	1.9629990633374	2.87429414038401	-0.911295077046604	1.3911826391893	1.19398698815987	0.754298951330831	0.65505063920123	0.76323702526362	0.356572315778433	NA	NA	0.0921087962447739	0.374711565105478	75.2964765725436
a4494	loss_cnaOV33_(ZFHX3)	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.27793497520355	8.81945546342657	-0.541520488223023	0.928062954963194	1.26171662002363	0.439759923339517	0.583495424881493	0.429193433477068	0.356641798095769	NA	NA	0.526290063785855	0.350148056699289	75.2964765725436
a4495	gain_cnaOV50	333	T0901317	LXR	4	28	2.32630161961136	NA	4.52683862420488	4.78571076958126	-0.258872145376376	0.7780629463833	1.15752006844998	0.230037641419549	0.332713627579493	0.223643764313329	0.356710812506097	NA	NA	0.00478863673992368	0.586399118034559	75.2964765725436
a4496	loss_cnaOV87, loss_cnaOV88	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.6073842419121	2.92442248477927	0.682961757132839	1.27237218463662	0.97177356174047	0.687143517049799	0.536762564742712	0.702799277549431	0.35685902207894	NA	NA	0.0852384218791047	0.452614605830389	75.3004422315808
a4497	loss_cnaOV85	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	0.693147180559945	3.29785026066565	2.69101632916204	0.606833931503608	1.54179349313618	1.55437700061984	0.391013981245471	0.393589630651014	0.390403313521507	0.356888322334245	NA	NA	0.968553182038058	0.378850805206541	75.3004422315808
a4498	PIK3CA_mut	295	NVP-BHG712	EPHB4	6	26	2.32630161961136	NA	3.35760918093894	3.22655758377041	0.131051597168532	0.927017523765917	1.12513970950829	0.119724198976336	0.14136906132707	0.116475843898359	0.356973152476937	NA	NA	0.060295387992563	0.771791341311687	75.3015958288895
a4499	gain_cnaOV51_(MYC)	1091	BMS-536924	IGF1R	8	24	1.38629436111989	NA	2.632140040293	2.31399780992101	0.318142230371993	0.968897038881484	0.930580292193642	0.338571416579264	0.328355044555884	0.341875099914315	0.357559424876286	NA	NA	0.732629596294079	0.432978091517515	75.3494812399288
a4500	loss_cnaOV20	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.86267542357494	4.45966322269478	0.40301220088016	1.24848121982002	0.873215972969747	0.438452797687339	0.322801972894921	0.461526373034088	0.357662657301585	NA	NA	0.524809569351297	0.571846309570171	75.3494812399288
a4501	loss_cnaOV34	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.72723226757643	2.33173727490985	0.395494992666579	1.11966120525541	0.907695809407409	0.421309778155796	0.353227378791214	0.43571314152566	0.35766629965061	NA	NA	0.7326312897152	0.489228938323468	75.3494812399288
a4502	loss_cnaOV1	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.2441954047667	0.262049446740401	0.982145958026302	1.70695491136005	1.65959825316951	0.590619707802058	0.575378969584941	0.591797416122	0.357753389762714	NA	NA	0.835793772612015	0.427083671840006	75.3494812399288
a4503	loss_cnaOV52, loss_cnaOV53	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	8	23	2.30258509299405	NA	1.89723514249148	1.23921273210941	0.65802241038206	1.71525677870115	1.35350719017241	0.45408479727846	0.38362909772631	0.486161000960947	0.357955515830595	NA	NA	0.472597433614132	0.347978863067708	75.3494812399288
a4504	loss_cnaOV87, loss_cnaOV88	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.46275933065543	3.44046821722451	1.02229111343092	0.876974952082634	1.74022817908753	0.603168346416582	1.16570160983868	0.587446592185945	0.357969707956918	NA	NA	0.696010847878541	0.165827628656163	75.3494812399288
a4505	KRAS_mut	1010	Gefitinib	EGFR	7	23	-0.693147180559945	NA	1.30442089433049	0.810079734556471	0.494341159774016	0.829061883859619	1.35673270971031	0.391598566358241	0.59626569427201	0.364361495993981	0.35826736139389	NA	NA	0.957084696455724	0.258016784290132	75.3494812399288
a4506	gain_cnaOV48_(SOX17)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	0.748385687038925	1.47980774704756	-0.731422060008631	0.582645876562433	1.50726381295665	0.500156092866942	1.25534581026123	0.485264791552232	0.358465265408898	NA	NA	0.472611710346252	0.150899892448664	75.3494812399288
a4507	SMARCA4_mut	152	CP466722	ATM	3	29	2.77258872223978	NA	2.181799160668	2.69503229097998	-0.513233130311979	1.26299633872164	0.762873542538548	0.636821733488557	0.406361534532597	0.672763048780192	0.358612915192937	NA	NA	0.552595370387408	0.556549038407569	75.3494812399288
a4508	PIK3CA_mut	193	GW-2580	CSF1R (cFMS)	6	26	2.99573227355399	NA	5.39578681696509	5.80278686426463	-0.407000047299534	0.628033019418157	0.578307313454175	0.693488937919334	0.648055173399323	0.70377814326532	0.358656994857981	NA	NA	0.188717525897258	0.189327401178027	75.3494812399288
a4509	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	4.40196117045607	3.75693332880239	0.645027841653678	1.79213280947257	1.68395441789208	0.377894612073899	0.359921897665336	0.383043528257199	0.358657445571335	NA	NA	0.143892335069319	0.417043830137627	75.3494812399288
a4510	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	219	AT-7519	CDK9	7	25	2.32630161961136	NA	2.00833653065028	1.354731635176	0.653604895474275	1.57212019536943	1.72552112915846	0.385391304404831	0.415747407481579	0.37878695567932	0.358665706519951	NA	NA	0.312106209748096	0.36302712658413	75.3494812399288
a4511	loss_cnaOV42	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	2.84093123738739	2.21277355614565	0.628157681241742	1.60807886444753	1.38113680396685	0.44666992625835	0.390626165873743	0.454812064552601	0.358665892622344	NA	NA	0.526343461400261	0.502686908416453	75.3494812399288
a4512	loss_cnaOV56	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	3.30234576648449	2.35040786149473	0.951937904989756	2.14998385801657	1.37765539364685	0.66011881777977	0.44276514051038	0.690984051149279	0.358726995800082	NA	NA	0.236258147877708	0.525456248849411	75.3494812399288
a4513	loss_cnaOV56	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	4.23864202492509	3.6238114639099	0.614830561015195	1.13395729909984	1.038790208751	0.588127094451739	0.542199041801009	0.591871732940615	0.358789338659684	NA	NA	0.82957577266868	0.449958926716912	75.3494812399288
a4514	loss_cnaOV70	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.66680793813475	4.89161528497135	0.775192653163399	0.444911298059556	1.26290572358491	0.632563033149567	1.74235326579554	0.613816723359936	0.358811930735064	NA	NA	0.368615603923259	0.0645851884406948	75.3494812399288
a4515	loss_cnaOV16, loss_cnaOV17	300	CX-5461	RNA Pol I	6	25	2.32630161961136	NA	4.16505186868972	3.38924307448457	0.775808794205154	1.06287763077093	1.79786650330318	0.457961080158776	0.729913558950755	0.431516351619978	0.358819316582751	NA	NA	0.696026460726454	0.19194608528492	75.3494812399288
a4516	gain_cnaOV19	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.17681977538439	2.29934303297701	0.877476742407375	1.68131015531797	1.26039084678364	0.679323113460352	0.521900578326921	0.696194156476607	0.35884164757224	NA	NA	0.107281051961092	0.463473347921914	75.3494812399288
a4517	loss_cnaOV20	1028	VX-702	p38	4	27	0.693147180559945	NA	3.77372277392965	3.26078351018333	0.512939263746325	0.776947929124429	0.931229915930467	0.55968717763868	0.6601977359337	0.550819142481914	0.35885869318231	NA	NA	0.514448406872972	0.291231277746228	75.3494812399288
a4518	loss_cnaOV56	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.50121535672632	5.73719666382865	-0.235981307102327	0.640891965683491	0.462690878039634	0.495084874415172	0.368207622716351	0.510019363472546	0.358930094880956	NA	NA	0.377764580694756	0.592224666795101	75.3494812399288
a4519	loss_cnaOV34	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	4.94214235320252	4.52293623738268	0.419206115819838	0.849225731860091	0.952274408277097	0.446349483716955	0.493633318083326	0.440215669113997	0.359106975719841	NA	NA	0.94266198368676	0.358376041473619	75.3494812399288
a4520	ARID1A_mut	1199	Tamoxifen	ER	9	23	1.6094379124341	NA	3.73758239282302	4.07464384032175	-0.33706144749873	0.541315255875486	0.814836455849229	0.448403166573364	0.622671250884275	0.413655335471511	0.359252099167497	NA	NA	0.522116552510813	0.187520753776732	75.3494812399288
a4521	loss_cnaOV16, loss_cnaOV17	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	6	25	2.32630161961136	NA	2.70598225446783	2.194908697547	0.511073556920834	1.28684095145344	1.43156071480738	0.363063237545614	0.397153631413109	0.357004457886092	0.359571495062113	NA	NA	0.526367119327734	0.417078034839637	75.3494812399288
a4522	loss_cnaOV70	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.45954071635379	3.44081306875683	1.01872764759697	1.08788521096813	1.73159667849192	0.600994758069734	0.936429356081032	0.588316933296611	0.359765368773493	NA	NA	0.696043785324681	0.240056530034404	75.3494812399288
a4523	PTEN_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.8729014803649	2.2103021793795	-0.337400699014593	1.18262660622152	1.32157392478038	0.25797432848799	0.28529774084196	0.2553021762068	0.359821805936651	NA	NA	0.683954839710314	0.626637905730623	75.3494812399288
a4524	gain_cnaOV18_(CCNE1)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	-0.959216435843681	-0.246132199922298	-0.713084235921383	2.23366808719175	1.27670885404325	0.509986650488852	0.319243597565069	0.558533164129858	0.359866101171234	NA	NA	0.888078028052839	0.573072365807168	75.3494812399288
a4525	loss_cnaOV1	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.770218791437	2.31931334706122	0.450905444375786	0.987268178078333	0.858090277521814	0.519895035039356	0.456720326237447	0.525475531173726	0.359931546610552	NA	NA	0.604925740026828	0.515913359540752	75.3494812399288
a4526	loss_cnaOV1	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.884170193627	4.36654189902319	0.51762829460381	0.258873400299686	0.976239270760492	0.547463812429838	1.99954222413186	0.530226871738705	0.359933684505065	NA	NA	0.784709194116312	0.0507487457569784	75.3494812399288
a4527	loss_cnaOV82	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.40438249921609	3.93592766776411	0.468454831451978	1.20123556507065	0.712230342084602	0.620673234882447	0.389977490738401	0.657729394230628	0.360032021460536	NA	NA	0.522136294677904	0.571114486523858	75.3494812399288
a4528	loss_cnaOV57_(ZNRF3)	263	FR-180204	ERK	4	28	2.99573227355399	NA	5.12093856644509	4.76759761775262	0.353340948692473	0.675122566064026	0.750916138329822	0.475122129378114	0.523373038398725	0.470546484029987	0.360188486098135	NA	NA	0.763303801251251	0.387494821891776	75.3494812399288
a4529	loss_cnaOV55	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-4.81741697428885	-3.75980422505502	-1.05761274923383	1.54251994365273	1.83330126981992	0.592356961217388	0.68563959486279	0.576889770734581	0.36021939294721	NA	NA	0.58469828014726	0.290517066672606	75.3494812399288
a4530	PIK3R1_mut	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	1.41630441874153	2.27482056020799	-0.858516141466455	2.65100893387489	1.30722038619872	0.56187914753679	0.323845057817889	0.656749351930582	0.360238634056172	NA	NA	0.946904268316848	0.634207499336011	75.3494812399288
a4531	loss_cnaOV20	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	6.00322454387493	5.67522432049245	0.328000223382485	0.893704772476656	0.536797721906958	0.549555225622181	0.367011829279509	0.611031325202488	0.360330048805593	NA	NA	0.188761529117751	0.466280314251722	75.3494812399288
a4532	loss_cnaOV38	261	TL-1-85	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	3.26396366182269	3.65281034880335	-0.388846686980661	1.31400489953262	0.810394705866022	0.408436235464815	0.295924837965955	0.479823824324127	0.360430636641284	NA	NA	0.726295316753153	0.451017433520473	75.3494812399288
a4533	gain_cnaOV4_(KRAS)	1018	ABT-888	PARP1, PARP2	5	26	1.6094379124341	NA	4.5809925516209	4.24546799579349	0.335524555827408	0.856367267938547	0.788214861624681	0.420477212047317	0.391799836809602	0.425676515583352	0.360469522373477	NA	NA	0.221215340195595	0.450955831260895	75.3494812399288
a4534	KRAS_mut	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	0.706766862031775	-0.0536280403502521	0.760394902382027	1.65160841078676	1.5908584003442	0.474175119539152	0.460396603344859	0.477977739701728	0.360560767266151	NA	NA	0.458044283680378	0.306518013166546	75.3494812399288
a4535	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-3.41996138267999	-4.37369562354372	0.953734240863726	2.52154718175476	2.2747654998458	0.409354555312224	0.378233747821453	0.419267058924701	0.360602532509806	NA	NA	0.927398662374936	0.393179801230481	75.3494812399288
a4536	gain_cnaOV94	164	JQ12	HDAC	3	16	1.63315443905142	NA	2.81718198529682	1.60202638349712	1.2151556017997	3.04481475394074	2.05486683520755	0.553694483509782	0.399090158186796	0.591354914576236	0.360716257833534	NA	NA	0.655495904538672	0.566113586046781	75.3494812399288
a4537	TP53_mut	283	GSK2126458	PI3K, MTOR	22	10	-2.05572501506252	0.0237165266173161	-2.53944679863017	-3.15620253427132	0.616755735641151	1.63516866497853	2.01768657044294	0.350692075508408	0.377181723727105	0.305674699269945	0.360757603901162	NA	NA	0.693869276186597	0.409965327749558	75.3494812399288
a4538	gain_cnaOV48_(SOX17)	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	3.8148480520438	4.33409938742	-0.5192513353762	1.29141676709152	0.763047971002447	0.640560467622785	0.402078824286632	0.680496318854028	0.360851238151315	NA	NA	0.312780653189486	0.560326189580403	75.3494812399288
a4539	loss_cnaOV39	1069	EHT 1864	Rac GTPases	10	23	2.30258509299405	NA	4.5473869216576	4.09103643785067	0.456350483806937	1.18760345821342	0.853112723451742	0.474240587264584	0.384261666342276	0.534924015621895	0.360860610170117	NA	NA	0.206033563665897	0.291726818672131	75.3494812399288
a4540	loss_cnaOV41	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.38333940973301	3.81505409722309	0.56828531250992	1.06468854128148	1.06256572771147	0.534685726985958	0.533757329468314	0.534823679786738	0.360960957817267	NA	NA	0.312601891789325	0.317058749840787	75.3494812399288
a4541	loss_cnaOV87, loss_cnaOV88	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.36674362384564	2.91518357410051	-0.548439950254864	0.8012631058511	0.792325375394021	0.691667426354278	0.684469241438881	0.692190313836821	0.360981357373593	NA	NA	0.0185836085819564	0.357921046283689	75.3494812399288
a4542	loss_cnaOV54	1017	Olaparib	PARP1, PARP2	10	21	1.6094379124341	NA	4.38696792920378	3.77090738690986	0.616060542293923	0.837413913903049	1.25122727904197	0.540875250227744	0.735670296451806	0.492365018420654	0.360999770228124	NA	NA	0.0803730521660612	0.117660208767874	75.3494812399288
a4543	loss_cnaOV81_(RB1)	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	3.22672481318525	2.80288235875696	0.423842454428285	0.663603679994521	1.10761748966261	0.395549655680435	0.638698167604773	0.382661395638841	0.361085672038902	NA	NA	0.302877317488257	0.323109227286509	75.3494812399288
a4544	gain_cnaOV94	1375	Temozolomide	DNA akylating agent	7	26	3.40119738166216	NA	6.16875828370668	5.88757817341158	0.281180110295091	0.820269213855454	0.665687243311142	0.402674058025947	0.342790032279134	0.422390714438954	0.361117022780187	NA	NA	0.90796781491458	0.426769390787097	75.3494812399288
a4545	PTEN_mut	1030	KU-55933	ATM	4	29	2.30258509299405	NA	3.60595794764939	4.22617223402467	-0.62021428637528	0.734086154330023	1.04277297114636	0.609844972137072	0.844879422826507	0.594774033789404	0.361226878891536	NA	NA	0.526407697436246	0.196889837076236	75.3494812399288
a4546	loss_cnaOV42	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-1.44080472388929	-2.41652354014409	0.975718816254797	1.18023106315593	1.63349438566792	0.611632910312106	0.826718467861479	0.597319969273009	0.361234700124997	NA	NA	0.121453512164673	0.204241969167801	75.3494812399288
a4547	loss_cnaOV82	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.76036157290597	2.94462623731927	0.815735335586701	1.51919111867413	1.14704907303068	0.69335812786645	0.536953728572763	0.711159927474947	0.361580584513923	NA	NA	0.0859891303872518	0.452594212445872	75.3494812399288
a4548	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	290	KIN001-260	IKK	5	26	2.99573227355399	NA	4.53777736553068	4.91033662420899	-0.372559258678308	1.12830069739317	0.855954145525644	0.41467306736915	0.330195008776534	0.435256094763719	0.361686011216856	NA	NA	0.66267183738065	0.515267576387652	75.3494812399288
a4549	gain_cnaOV94	1052	RO-3306	CDK1	7	26	1.6094379124341	NA	3.22265570045671	3.55155603407138	-0.328900333614672	0.781016526028322	0.928536904662582	0.36468717721479	0.421118276827275	0.354213528792579	0.361726336961802	NA	NA	0.79260745106489	0.363271319635375	75.3494812399288
a4550	loss_cnaOV85	1011	ABT-263	BCL2, BCL2L1, BCL2L2	7	26	0.693147180559945	NA	2.09357380024406	1.64200009266091	0.45157370758315	1.42266019473513	1.76503180347426	0.264985807342144	0.317415015373522	0.255844516055903	0.361877197034328	NA	NA	0.225657737140338	0.494126697795508	75.3494812399288
a4551	SMARCA4_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	0.934999001445595	1.65736019809284	-0.722361196647241	0.892542643276615	1.06991224069676	0.685153078325683	0.809329618129369	0.675159297342759	0.361912681179873	NA	NA	0.448725550461313	0.294813654702432	75.3494812399288
a4552	loss_cnaOV1	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	2.94559029494911	2.2239942885941	0.72159600635501	1.89656257696252	1.36250866359214	0.513274253046451	0.380475717026273	0.529608380215788	0.361960470926095	NA	NA	0.526429133273498	0.580969001551679	75.3494812399288
a4553	gain_cnaOV18_(CCNE1)	333	T0901317	LXR	4	28	2.32630161961136	NA	5.37832740347172	4.66406951540028	0.714257888071441	0.399370121626899	1.15410147994378	0.6480666338031	1.78846100244504	0.618886554158336	0.362039829011277	NA	NA	0.00480066345760469	0.0319106334770457	75.3494812399288
a4554	loss_cnaOV102	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	2.47292664160488	1.43361738763472	1.03930925397016	0.810606623449767	1.9642998163981	0.544368748325391	1.28213762866516	0.529099094391774	0.362174081519939	NA	NA	0.780853204531299	0.139830993110697	75.3494812399288
a4555	TP53_mut	192	LFM-A13	BTK	12	7	2.77258872223978	NA	4.84065210707778	4.52697067389133	0.313681433186455	0.585380344625411	0.829021464540811	0.460353411224082	0.535859182950841	0.37837552657361	0.362197280890591	NA	NA	0.956251931503032	0.399870052736837	75.3494812399288
a4556	gain_cnaOV50	255	CP724714	ERBB2	4	28	2.32630161961136	NA	4.80849132371859	4.35886644134569	0.449624882372896	0.473704206078773	0.984452121737959	0.475355659959254	0.949168017938449	0.456726002661383	0.36223579656458	NA	NA	0.784738609813929	0.17616086374252	75.3494812399288
a4557	TP53_mut	1219	PFI-1	BRD2, BRD3, BRD4	22	10	2.30258509299405	NA	2.46340285082602	2.13758807209139	0.325814778734625	0.945965393384125	0.632228236737482	0.377147646692362	0.344425685139543	0.515343605049882	0.362236184962217	NA	NA	0.604976205750329	0.261958591096088	75.3494812399288
a4558	loss_cnaOV42	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	4.95518547502259	4.21860853769278	0.736576937329814	1.5354600033733	1.26892443488155	0.567858268450204	0.479710924225707	0.580473444345463	0.362259963190703	NA	NA	0.367342472736745	0.416442755244824	75.3494812399288
a4559	NF1_mut	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.62986935341956	4.37761879800042	0.252250555419141	0.550576839241687	0.639711326226756	0.399532432503508	0.458156859207095	0.39431935167852	0.362313499345332	NA	NA	0.267290158218419	0.446075360806522	75.3494812399288
a4560	loss_cnaOV82	1061	SB590885	BRAF	3	30	1.6094379124341	NA	4.52409580342885	3.86788422633895	0.656211577089905	1.26353357337567	1.28030230884086	0.512975048081601	0.519346371886867	0.512544242526609	0.362326261205181	NA	NA	0.570106581740159	0.467763181845552	75.3494812399288
a4561	gain_cnaOV4_(KRAS)	263	FR-180204	ERK	8	24	2.99573227355399	NA	5.02543306320484	4.74054262738395	0.284890435820886	0.867857150553563	0.699992686095874	0.383658241294661	0.328268812026459	0.406990589301481	0.362373616989228	NA	NA	0.763334302173304	0.419219647725723	75.3494812399288
a4562	gain_cnaOV18_(CCNE1)	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	3.23593697302997	2.90636013429399	0.329576838735977	0.433504544204619	0.622381218974478	0.555371919868271	0.760261554675683	0.529541748189372	0.362374565935762	NA	NA	0.847264858612523	0.262760663109447	75.3494812399288
a4563	SMARCA4_mut	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.84710537224391	4.35253788387513	0.494567488368777	0.899899131913615	0.85188770419042	0.578396472631055	0.549581026172445	0.58055479136042	0.36242336898096	NA	NA	0.868492314150279	0.444750548262143	75.3494812399288
a4564	gain_cnaOV4_(KRAS)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	5	26	-1.6094379124341	NA	1.00638045540645	0.480961096468109	0.52541935893834	0.699024399029185	1.26872994257696	0.435579270859788	0.751646665936196	0.414130179564566	0.362441422131473	NA	NA	0.427036946581373	0.217769536243574	75.3494812399288
a4565	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1005	Cisplatin	DNA crosslinker	8	23	1.79175946922805	2.30258509299405	3.38163878886077	2.89902213272918	0.482616656131593	1.1626858908993	1.18892799796511	0.408081745160125	0.415087737719345	0.405925890346268	0.362670092180063	NA	NA	0.0860095227106886	0.333797660325793	75.3660878105338
a4566	gain_cnaOV4_(KRAS)	286	KIN001-236	TIE2	8	24	2.32630161961136	NA	4.9848671850604	4.7318052029772	0.253061982083204	0.775829717145719	0.620579751751766	0.383381415925554	0.326182378027771	0.407783175923583	0.362694390004687	NA	NA	0.76020070814405	0.421526392623971	75.3660878105338
a4567	gain_cnaOV48_(SOX17)	1262	UNC1215	LMBL3	3	30	0	NA	2.59745687788091	2.79870828720539	-0.201251409324482	0.339670312004346	0.504180466036154	0.406388852530669	0.592490430314403	0.399165423656162	0.362783325651216	NA	NA	0.107034601478142	0.422085124099519	75.3660878105338
a4568	PIK3R1_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	0.848236336956693	-0.835181165254815	1.68341750221151	3.20215268220973	1.48385331729233	0.948632300283508	0.525714314487284	1.134490506975	0.362839024470248	NA	NA	0.0399502383141045	0.45998101572045	75.3660878105338
a4569	loss_cnaOV16, loss_cnaOV17	1033	Vismodegib	SMO	6	25	2.30258509299405	NA	5.2861161408125	4.8209018477728	0.465214293039692	1.07569386695813	0.790231869648237	0.549673417439909	0.432478335453594	0.588706063255557	0.362980052480586	NA	NA	0.150882148382051	0.355295675849936	75.3714341500982
a4570	loss_cnaOV34	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	2.98072422872858	2.66701950300275	0.313704725725832	0.838100392906562	0.506268093663813	0.558242923178732	0.374304472806525	0.619641509413682	0.363023636129844	NA	NA	0.132544576925688	0.458115628598862	75.3714341500982
a4571	loss_cnaOV81_(RB1)	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.72341534580335	4.41315105167202	0.310264294131334	0.350209789639755	0.568894675130716	0.563148069078943	0.885938381249962	0.545380907388604	0.36325350481585	NA	NA	0.360996536054609	0.185257524523793	75.3874681814946
a4572	MLL2_mut	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	3.75967442003547	4.56273335784212	-0.80305893780665	1.05694833799711	0.62839644660706	1.20862678750094	0.75979015145473	1.27794952078844	0.363307662518483	NA	NA	0.0791946176730816	0.317694730361514	75.3874681814946
a4573	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.16441258382167	-4.13584334509473	0.971430761273068	2.44801496938143	1.70009170272679	0.538413358327888	0.396823864814247	0.571399036719598	0.363339222859094	NA	NA	0.584827876416728	0.568499099007682	75.3874681814946
a4574	KRAS_mut	152	CP466722	ATM	7	25	2.77258872223978	NA	2.36096115887861	2.72698423233092	-0.366023073452314	0.636734633070584	0.842529416994121	0.454355581338074	0.574843984356885	0.434433583053003	0.363432982602423	NA	NA	0.552711341266807	0.235536593598941	75.3884900677914
a4575	gain_cnaOV4_(KRAS)	1005	Cisplatin	DNA crosslinker	5	26	1.79175946922805	2.30258509299405	3.41755562179296	2.94780158671895	0.469754035074011	0.547585042054297	1.26204069020181	0.394986209675369	0.85786498716565	0.372217820487938	0.363581270495168	NA	NA	0.0860265144379643	0.198688438055801	75.3884900677914
a4576	gain_cnaOV48_(SOX17)	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	2.8892802691339	3.31621613894985	-0.426935869815947	0.140175632154935	1.077887421783	0.409740312688721	3.04572102335203	0.396085770357843	0.363582510626373	NA	NA	0.0894298804097574	0.0580611389724548	75.3884900677914
a4577	loss_cnaOV56	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	5.05366273934868	4.38928026600217	0.664382473346507	1.37300262244671	0.936780492582484	0.683540745208415	0.483890170699433	0.709218945747856	0.363700955007953	NA	NA	0.0300473678602582	0.492263646730855	75.3965728746139
a4578	gain_cnaOV19	1248	FK866	NAMPT	3	29	0	NA	0.0154895574217783	-1.88668678096065	1.90217633838242	1.65069271736284	2.78162515248565	0.699099875296923	1.15235035471735	0.683836330960211	0.363825662711593	NA	NA	0.0429803160994768	0.168477782640641	75.4059502768331
a4579	loss_cnaOV56	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	5.06241493307189	4.53940501296997	0.523009920101916	1.20948657736382	0.916791839007845	0.556898818020371	0.432423087523519	0.570478376714086	0.363955737580658	NA	NA	0.942678862448575	0.535204466658833	75.4164357307848
a4580	gain_cnaOV18_(CCNE1)	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-1.58319858295028	-2.80224309439192	1.21904451144163	2.20105317069632	1.90302830720503	0.622304908296729	0.553846007752725	0.640581386428267	0.364040625172465	NA	NA	0.338084797589759	0.365527584627028	75.4175552496926
a4581	loss_cnaOV20	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.54988864278507	3.09755452790829	-0.547665885123219	1.50381541334818	0.98811331396412	0.511209502259626	0.364184247788673	0.554254129950024	0.364178131837619	NA	NA	0.430844747161022	0.471188711166208	75.4228524975785
a4582	loss_cnaOV56	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.88506467756717	4.34794560254523	0.537119075021939	0.812086642674146	0.756968276483434	0.705901789673644	0.661406119491441	0.709566162425162	0.364358826859971	NA	NA	0.0414799049326111	0.371289785572772	75.4228524975785
a4583	KRAS_mut	304	SB52334	ALK5	7	25	2.99573227355399	NA	4.76807256130574	4.25423949258564	0.513833068720096	0.403461279890957	1.15476270483649	0.490068157696742	1.27356228300016	0.444968534719739	0.364373794726789	NA	NA	0.347979877568897	0.07387111675371	75.4228524975785
a4584	loss_cnaOV36	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	3.21457690300509	1.92059184858073	1.29398505442436	4.06278019755669	1.7210129505313	0.658208629367904	0.318497430700914	0.751874094860756	0.364390073659997	NA	NA	0.129448533768864	0.637737513597743	75.4228524975785
a4585	MLL2_mut	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	2.70205410878604	3.64715457499974	-0.945100466213692	0.590903632137736	0.897644402602878	1.07265752171992	1.59941556425125	1.05286733084193	0.364463647171991	NA	NA	0.139908268365989	0.087415283324448	75.4228524975785
a4586	PTEN_mut	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-1.55685560691698	-1.12048342068301	-0.43637218623397	1.35626831636826	1.33348676626546	0.326705808844472	0.321744732194633	0.327241482460353	0.364652518984278	NA	NA	0.0468825145925981	0.643323888380088	75.4454831675587
a4587	gain_cnaOV48_(SOX17)	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	5.1173719320652	5.89531691033916	-0.777944978273953	2.10187715695951	1.19525350294915	0.609723673597432	0.370119145972972	0.650861910343258	0.364798491283018	NA	NA	0.567863652218176	0.589131326414574	75.4464991040423
a4588	RB1_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-2.79916497640107	-1.90886655087068	-0.890298425530389	0.941189981108215	2.08703703645031	0.437988597345984	0.945928498391044	0.426584871270244	0.364873698419396	NA	NA	0.274649129482066	0.245146011468031	75.4464991040423
a4589	loss_cnaOV44	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.76234937530007	1.81421083643107	0.948138538869005	1.03786234504771	1.38173822215433	0.69604759406366	0.9135494156746	0.686192596880411	0.364895975407596	NA	NA	0.032984603312819	0.24812831193447	75.4464991040423
a4590	SMAD4_mut	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.69435665456409	5.16317871416428	0.531177940399809	1.19282875943939	0.643687089978377	0.732127035285604	0.445309468099556	0.825211424416874	0.365146220892033	NA	NA	0.121575080270268	0.523835831298765	75.4817918584807
a4591	gain_cnaOV95_(MECOM)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	9	23	0.246860077931526	2.32630161961136	0.594579019436614	1.16445551170168	-0.569876492265069	1.14689965897466	1.65935455720266	0.370176912140588	0.496884350610534	0.343432625529872	0.365230269715154	NA	NA	0.789361301762029	0.281405127319157	75.4827211096645
a4592	gain_cnaOV96	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.6931352354686	4.30617848394216	0.386956751526442	1.09039038291972	1.05678237678318	0.364597814222639	0.354879094302259	0.366165030783662	0.365876053724982	NA	NA	0.348022669049253	0.494011068000551	75.599719379218
a4593	loss_cnaOV57_(ZNRF3)	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.23833126006868	4.54490897910632	-0.306577719037634	0.529094549623905	0.601564983337729	0.513524175599288	0.579438437337065	0.509633584948072	0.36618142249578	NA	NA	0.612235189600186	0.425881078948196	75.6334241555836
a4594	loss_cnaOV35	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	2.29696090640777	1.10339878662902	1.19356211977875	2.9779567818683	2.18115957755801	0.518178541355827	0.400799006569175	0.547214487220162	0.366247064348045	NA	NA	0.359701432983759	0.433048688192521	75.6334241555836
a4595	gain_cnaOV18_(CCNE1)	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.44789838876455	3.44206046099853	1.00583792776602	1.82968299474454	1.68544698156469	0.593138888276195	0.549733440522278	0.596778147736364	0.366305133956881	NA	NA	0.696161826264461	0.444706842272999	75.6334241555836
a4596	SMARCA4_mut	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-1.33912229007093	-0.680519432385442	-0.658602857685493	1.19956887575842	0.887002899767643	0.723411446954753	0.549032965922105	0.74250361284954	0.366358022442601	NA	NA	0.0404843948621593	0.443622313497001	75.6334241555836
a4597	loss_cnaOV39	308	XL-880	MET	9	23	1.63315443905142	NA	-0.0503716278392389	0.371847542314038	-0.422219170153277	0.381768293901579	1.09634479363265	0.440119306206973	1.1059566153027	0.385115314639554	0.366464873394102	NA	NA	0.364528216306892	0.117098454775533	75.6390256101982
a4598	loss_cnaOV82	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.30840228874675	5.91110445428026	0.397297834466491	1.01062081291239	0.671549435569078	0.568860137850329	0.39312255337545	0.591613682364005	0.366551686614849	NA	NA	0.907996811817337	0.568756819301559	75.6404897032457
a4599	gain_cnaOV18_(CCNE1)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	1.42117702844406	0.790406310842162	0.6307707176019	0.527829442181557	1.29305530491705	0.50950631833375	1.19502753577913	0.487814183355726	0.366674028015992	NA	NA	0.843671702661111	0.111382756232071	75.6418618783334
a4600	gain_cnaOV18_(CCNE1)	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.552449707308916	-0.182426336107978	0.734876043416894	1.1371821683822	1.2583330130514	0.587734056682256	0.646225436741024	0.584007600368722	0.366797499905432	NA	NA	0.765269088048145	0.381805657456074	75.6418618783334
a4601	gain_cnaOV19	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.552449707308916	-0.182426336107978	0.734876043416894	1.1371821683822	1.2583330130514	0.587734056682256	0.646225436741024	0.584007600368722	0.366797499905432	NA	NA	0.765269088048145	0.381805657456074	75.6418618783334
a4602	loss_cnaOV36	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.41339086239285	3.07390492690588	-0.660514064513035	1.74617338556944	1.0073372998125	0.615837591751394	0.378263733699983	0.655702975196075	0.367211615845446	NA	NA	0.430927548011396	0.581670290982824	75.6882996052702
a4603	loss_cnaOV59	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.43136603985819	-4.15287024634764	0.721504206489455	2.26937919026646	1.40450168314414	0.475608558964822	0.317930211744269	0.513708324559842	0.36723304831608	NA	NA	0.862977383691365	0.57576111967889	75.6882996052702
a4604	loss_cnaOV57_(ZNRF3)	1248	FK866	NAMPT	4	28	0	NA	-0.191149556759466	-1.92510177673413	1.73395221997466	3.55582194228926	2.60683119790453	0.63825938026347	0.487637527445575	0.665157077055269	0.367336792848014	NA	NA	0.0430211414524054	0.407892073153497	75.6882996052702
a4605	loss_cnaOV56	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.87821470170092	3.96348700607745	0.91472769562347	1.63537692984445	1.76855374578856	0.519734941541817	0.559337531874364	0.517217923289977	0.367341763444491	NA	NA	0.619459491630609	0.439358811916489	75.6882996052702
a4606	gain_cnaOV26	333	T0901317	LXR	3	29	2.32630161961136	NA	5.44817434905398	4.68147355165286	0.766700797401121	0.452691036975404	1.1373323938185	0.693867640030604	1.69365137539221	0.6741220082785	0.367666978460315	NA	NA	0.00481312659697714	0.0683825386571675	75.7271888428151
a4607	loss_cnaOV40	299	OSI-027	MTORC1/2	7	25	2.99573227355399	NA	2.0750254198989	1.37874024907717	0.696285170821725	1.9364169688549	1.90545862236165	0.364224861355849	0.359573987431784	0.365416053988482	0.367690128871996	NA	NA	0.780923832257102	0.419474430037979	75.7271888428151
a4608	ARID1A_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	9	23	2.30258509299405	NA	0.584284849698674	0.980761790002988	-0.396476940304314	0.66711331407287	1.39471367931438	0.318954598527943	0.594317235079206	0.284271206473875	0.367838518579975	NA	NA	0.843682390508001	0.287895725003234	75.7413097869204
a4609	gain_cnaOV48_(SOX17)	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-5.16616446673453	-4.59311896962796	-0.573045497106566	1.24891935555877	1.43433918663859	0.402892690432746	0.458833066007038	0.399518818452916	0.367934258832229	NA	NA	0.132388088050932	0.518367229812722	75.7419007160235
a4610	gain_cnaOV4_(KRAS)	225	Genentech Cpd 10	AURKA, AURKB	8	24	2.32630161961136	NA	2.32758926284663	3.01634025612199	-0.688750993275357	1.74268760340749	1.87210132180397	0.373769090230275	0.39522344218702	0.367902626451689	0.368001041814174	NA	NA	0.342588498990023	0.35965930652758	75.7419007160235
a4611	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.11828959263285	2.47892009741731	0.639369495215538	1.28197606601249	1.00628842331121	0.622977756934054	0.498737466452287	0.635373994576707	0.368370536215397	NA	NA	0.39158807101578	0.481332565488145	75.8015071364773
a4612	PIK3R1_mut	1248	FK866	NAMPT	5	27	0	NA	-3.29534099510768	-1.414471962965	-1.88086903214268	1.89941417492872	2.7913286071309	0.699324611139177	0.990236388129128	0.673825728485603	0.368497146650213	NA	NA	0.0430345200699085	0.0998773563913866	75.8111190575837
a4613	gain_cnaOV4_(KRAS)	157	JNK-9L	JNK	6	13	1.63315443905142	NA	0.33087283540881	-0.198748335761859	0.529621171170669	0.962532961482354	0.997064304161657	0.536578751251507	0.55023691900901	0.531180555717497	0.368730388536534	NA	NA	0.184475313429202	0.295833260125791	75.8293509776537
a4614	loss_cnaOV54	150	Bicalutamide	ANDR (androgen receptor)	6	13	0.0237165266173161	NA	3.17106231688057	2.88559815424972	0.285464162630855	0.22480354126971	0.691772426035704	0.480697209354608	1.26983837095505	0.412656174035074	0.368821002737235	NA	NA	0.847371737438705	0.198155828523654	75.8293509776537
a4615	loss_cnaOV38	258	STF-62247	stimulates autophagy	8	23	2.32630161961136	NA	4.40607367460751	4.51850355686684	-0.112429882259334	0.672829034495303	0.682742733175732	0.165249848505706	0.167100223823826	0.164673861465172	0.368825523604816	NA	NA	0.0516262868423199	0.691978132237773	75.8293509776537
a4616	MLL2_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-1.73741709812811	-2.01504133869798	0.277624240569871	0.769834806015151	2.10789882801922	0.135550499698014	0.360628330130877	0.131706625042699	0.368989772234424	NA	NA	0.274760607442414	0.653750479282463	75.8312327764217
a4617	TP53_mut	290	KIN001-260	IKK	21	10	2.99573227355399	NA	4.74458220391893	5.07214127747896	-0.327559073560036	1.03182089878328	0.467954111695329	0.365718740208102	0.317457297042822	0.699981184850236	0.368994518144527	NA	NA	0.662815030912463	0.233899345084737	75.8312327764217
a4618	PTEN_mut	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	0.0770165657897948	1.71924805462692	-1.64223148883713	1.25422790639613	1.57758184852688	1.05398670786022	1.30935652161964	1.04098021308411	0.369105064038538	NA	NA	0.0766262325808761	0.136183807672551	75.8375250994775
a4619	gain_cnaOV26	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.70432274014352	2.25002079279615	0.454301947347374	0.743153919993002	0.907990462555383	0.506132557657129	0.611316088262916	0.50033779657643	0.369266125069348	NA	NA	0.591426568129797	0.405623149912107	75.8541914550211
a4620	loss_cnaOV34	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	4.61142110000224	3.69159312830211	0.919827971700137	1.29738160503811	1.50587140427588	0.626396769129527	0.708987986362823	0.610827703539831	0.369436071706447	NA	NA	0.0667491424204226	0.216584440180475	75.8726754708843
a4621	loss_cnaOV84	1052	RO-3306	CDK1	6	27	1.6094379124341	NA	3.80077898045064	3.41090270023515	0.389876280215492	1.05558638794488	0.865881768666711	0.433585895950266	0.369345687542013	0.450265029619257	0.369776604430831	NA	NA	0.792701675436146	0.428382286249357	75.8744061960824
a4622	loss_cnaOV39	1067	CCT007093	PPM1D	10	23	1.88706964903238	NA	4.73490574767803	4.38312897906912	0.35177676860891	0.712308368460665	0.674730963218412	0.512904283885638	0.493854605932986	0.521358567763014	0.3698496329549	NA	NA	0.0793021378758416	0.203508221311882	75.8744061960824
a4623	SMARCA4_mut	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.24455101792156	5.04312047035459	0.201430547566974	0.467333070964794	0.62917616958219	0.325043680453758	0.431021385135717	0.320149677157569	0.369883997368155	NA	NA	0.107944505664867	0.545458478763412	75.8744061960824
a4624	loss_cnaOV39	1219	PFI-1	BRD2, BRD3, BRD4	9	23	2.30258509299405	NA	2.109527593884	2.46021717800567	-0.350689584121672	0.871980351286873	0.859194815144739	0.406538727747993	0.402176016471153	0.408160731350078	0.369974538130634	NA	NA	0.605142421034241	0.321234844913477	75.8744061960824
a4625	loss_cnaOV82	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.26204087397492	4.51385887795974	-0.251818003984822	0.882963654652947	0.660187158348609	0.371464749603248	0.285196341500376	0.381434265723555	0.370003163827028	NA	NA	0.051642020681732	0.674070361019055	75.8744061960824
a4626	KRAS_mut	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.4423275086409	4.29640432513731	0.145923183503588	0.4338955432677	0.623152276960036	0.2477446988912	0.336309477632864	0.234169381865143	0.370017439707479	NA	NA	0.250304087853087	0.49347512181749	75.8744061960824
a4627	gain_cnaOV51_(MYC)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	8	23	0.693147180559945	NA	0.46657177742692	-0.374942318984868	0.841514096411788	1.74081358578721	1.52093374440672	0.533678659918139	0.483402762525689	0.553287807247674	0.370113080411268	NA	NA	0.0979869474969792	0.24973316754085	75.8744061960824
a4628	loss_cnaOV34	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.22754459538173	2.5528894352244	0.674655160157326	1.86357419874401	1.6728434129867	0.397169588044372	0.362022161828609	0.403298452754042	0.370237505457884	NA	NA	0.637540425724133	0.481880389717226	75.8744061960824
a4629	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	305	TPCA-1	IKK	7	25	2.99573227355399	NA	3.70342588129562	3.2192903678725	0.484135513423121	1.38480561487046	1.17953347785645	0.395746836275517	0.34960539459425	0.410446606655822	0.370294768919665	NA	NA	0.99356194813219	0.421917950766455	75.8744061960824
a4630	gain_cnaOV51_(MYC)	277	ABT-869	VEGFR and PDGFR family	8	24	0.0237165266173161	NA	2.92390802129242	2.64674514809907	0.277162873193352	0.525393648903232	0.570873701873836	0.494411203946496	0.527533733557561	0.485506465411863	0.370412631853327	NA	NA	0.132708693335892	0.228467144730126	75.8744061960824
a4631	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	6	17	2.30258509299405	NA	1.88909716388693	1.44809517546306	0.44100198842387	1.65705467805032	0.794999570970431	0.41388819710662	0.266136051070295	0.554719781654162	0.370417627103992	NA	NA	0.449057576660813	0.554431829982384	75.8744061960824
a4632	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	2.41736252107118	1.66983104825595	0.747531472815231	1.59077270821024	1.70765742331247	0.43963156719172	0.469917210018186	0.437752597570295	0.370660405817744	NA	NA	0.225887274705417	0.507428453979003	75.8744061960824
a4633	loss_cnaOV82	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.87181894633998	3.96414863594238	0.907670310397598	1.64037872353358	1.76857593415416	0.515628036087438	0.553329726468508	0.513221000506095	0.370849583370404	NA	NA	0.61953179980773	0.443631756673418	75.8744061960824
a4634	loss_cnaOV43_(NF1)	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.8802027856486	4.3637921183449	0.516410667303701	1.0340271335015	0.994578521854093	0.516536632398738	0.499416940399805	0.519225637751565	0.370880211644791	NA	NA	0.371421754577073	0.344903800466306	75.8744061960824
a4635	gain_cnaOV94	1061	SB590885	BRAF	7	26	1.6094379124341	NA	4.25682488298096	3.83888615459955	0.417938728381409	1.46984683243782	1.23251670892561	0.326034397335756	0.284341687281957	0.339093762668522	0.370924489525193	NA	NA	0.570296648487608	0.508876205794822	75.8744061960824
a4636	loss_cnaOV16, loss_cnaOV17	224	AS605240	PI3Kgamma	6	26	2.99573227355399	2.32630161961136	3.87267060173128	3.26027733379724	0.612393267934043	1.09571578077937	1.75613548088134	0.367944234461717	0.55889791739465	0.348716414309165	0.370970264377516	NA	NA	0.627133068503832	0.299605383119051	75.8744061960824
a4637	gain_cnaOV72_(ASXL1)	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.27915682620359	2.5537199566388	-0.274563130435209	0.560742101452893	0.635667595383145	0.438462163701211	0.489642439409866	0.431928782321707	0.371033959301803	NA	NA	0.857021610657256	0.362640349592798	75.8744061960824
a4638	loss_cnaOV84	1028	VX-702	p38	6	25	0.693147180559945	NA	3.67775951399374	3.24277955146824	0.434979962525503	0.787975923813425	0.941064142761567	0.474612067160949	0.552021894806644	0.462221375526058	0.371101885938847	NA	NA	0.514766298771575	0.273842929875736	75.8744061960824
a4639	gain_cnaOV19	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.7121019912746	4.09488402011631	0.617217971158292	1.13359639834519	1.01380575237594	0.603956300382915	0.544477710108551	0.608812851684646	0.371102273176461	NA	NA	0.526641906656518	0.447977233253447	75.8744061960824
a4640	loss_cnaOV56	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	5.08803998477673	4.47229999560155	0.615739989175176	1.13724986703184	0.967488338963529	0.628736525076732	0.541428939255211	0.636431432170871	0.371107511666297	NA	NA	0.321973650600986	0.449837132675256	75.8744061960824
a4641	KRAS_mut	1067	CCT007093	PPM1D	7	26	1.88706964903238	NA	4.2090760637795	4.56528813649667	-0.356212072717173	0.628322980780395	0.703595014209067	0.516498130599956	0.566925106375622	0.506274299168538	0.37112379205824	NA	NA	0.0793227813547557	0.222566162102539	75.8744061960824
a4642	gain_cnaOV94	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.52129003203895	2.22768834143542	0.293601690603527	0.835511484072197	0.915286395562444	0.326455523369544	0.35140353687605	0.320775761583465	0.371366066568187	NA	NA	0.591473800280096	0.44117961618592	75.9075821421877
a4643	PTEN_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	1.29616237610681	2.4884253419167	-1.19226296580989	1.18250072405227	1.54462996513608	0.787816209653719	1.00825559051175	0.771876108013258	0.371825563029452	NA	NA	0.238763350795066	0.135097777653422	75.9260109307738
a4644	loss_cnaOV102	1026	17-AAG	HSP90	3	30	0	NA	0.867770205162953	-0.670692394635349	1.5384625997983	0.573988856470596	2.34230939281973	0.677683774742712	2.68030046655987	0.656814426187424	0.37187830955918	NA	NA	0.0594948786522583	0.0148756006283746	75.9260109307738
a4645	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1047	Nutlin-3a	MDM2	8	25	2.07944154167984	1.38629436111989	4.20158957076674	3.60245601729911	0.599133553467632	1.71405817833502	1.49967569340527	0.386368899613335	0.349540967185612	0.399508744525424	0.371959456618333	NA	NA	0.162168698981037	0.395126535928005	75.9260109307738
a4646	gain_cnaOV51_(MYC)	1031	Elesclomol	HSP70	8	23	-1.6094379124341	NA	-3.66949317739671	-4.19552240833241	0.526029230935699	1.24215930511684	1.59699976338971	0.346309445702232	0.42347968474641	0.329385916638569	0.371970331706971	NA	NA	0.863016651634368	0.354319302170664	75.9260109307738
a4647	PIK3R1_mut	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.02876711649063	4.3871600300511	-0.358392913560466	0.442172123635529	0.595167670404448	0.621687581422275	0.810528060009228	0.602171339913202	0.372055041722735	NA	NA	0.250361400704354	0.161741302888444	75.9260109307738
a4648	gain_cnaOV51_(MYC)	328	SNX-2112	HSP90	8	24	0.940007258491471	NA	1.33991158252172	0.481561562471399	0.858350020050322	2.67775192179385	2.16911434178977	0.373538523809963	0.320548745783479	0.39571451053248	0.37206602474225	NA	NA	0.945424705308088	0.430184171785061	75.9260109307738
a4649	loss_cnaOV16, loss_cnaOV17	303	PIK-93	PI4K, PI3K	6	26	2.99573227355399	NA	2.40025237036702	3.02187767578192	-0.621625305414895	0.768147333063871	1.30603737231119	0.504240132619757	0.80925270277962	0.475962877168554	0.372089405869809	NA	NA	0.228132249635245	0.149139639809118	75.9260109307738
a4650	gain_cnaOV72_(ASXL1)	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	1.42550479609319	2.03449965255429	-0.608994856461101	0.911361020397101	1.38718210269489	0.456660050883253	0.668225700717097	0.43901579704496	0.372096392393007	NA	NA	0.837834463694735	0.246890842456707	75.9260109307738
a4651	PIK3CA_mut	1028	VX-702	p38	7	24	0.693147180559945	NA	2.98038917181961	3.42805506949713	-0.447665897677526	1.07135564826789	0.867319960934598	0.490172781923833	0.417849944041727	0.51614850094668	0.372244441961321	NA	NA	0.514795214052642	0.339265986169472	75.9391492635359
a4652	gain_cnaOV72_(ASXL1)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.04451053444329	3.55555165283878	-0.511041118395487	1.01140776583946	1.12009545224727	0.460668899282338	0.505277036281531	0.456247829031155	0.372395262802748	NA	NA	0.724726024289628	0.403145344550958	75.9391492635359
a4653	loss_cnaOV39	1259	BMN-673	PARP1	10	23	2.30258509299405	NA	1.81604080954802	1.93708544014574	-0.121044630597721	1.38457194851886	1.39181674604204	0.0871001820695546	0.0874238646299369	0.0869687988321304	0.37246852588902	NA	NA	0.0330549933170059	0.82045998342071	75.9391492635359
a4654	PTEN_mut	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.49221527142452	2.95993856339247	0.532276708032045	0.84407386814764	1.67021493956799	0.326904625786889	0.630604415227487	0.318687550579401	0.37249507594345	NA	NA	0.661052463539636	0.410172760952032	75.9391492635359
a4655	gain_cnaOV4_(KRAS)	344	THZ-2-49	CDK9	8	24	2.99573227355399	NA	3.23332896528501	2.37187049223658	0.861458473048425	2.02928966601375	2.40388687891183	0.371015621815817	0.424512324423668	0.358360653575506	0.372630305474696	NA	NA	0.382406325830225	0.338305945441957	75.9391492635359
a4656	loss_cnaOV82	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.10504715128608	5.73777032827593	0.367276823010156	0.630420972282524	0.552469830130411	0.657971826396116	0.582589791834465	0.664790732416031	0.372640987881001	NA	NA	0.107995822280069	0.421315697648982	75.9391492635359
a4657	loss_cnaOV38	287	KIN001-244	PDPK1 (PDK1)	8	24	2.99573227355399	NA	3.2708573113597	3.63554445981355	-0.364687148453847	0.851502850763382	0.910257002228507	0.406612096597698	0.428286468009944	0.400641958876465	0.372779056180759	NA	NA	0.660875914746806	0.321720751322198	75.9448839654841
a4658	gain_cnaOV94	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	7	24	2.30258509299405	NA	1.9234808840261	1.2589753245944	0.664505559431693	1.21443066119704	1.50688711112679	0.457893655675908	0.547174557316188	0.440978992072474	0.372969071528243	NA	NA	0.473006442526375	0.252371100132076	75.9448839654841
a4659	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.81978648705009	-3.82026144948501	1.00047496243492	2.51563327070634	1.58951432020846	0.585498613441925	0.397703025351549	0.629421798668486	0.373241039140143	NA	NA	0.241576263009888	0.490275688366844	75.9448839654841
a4660	loss_cnaOV39	1043	JNK Inhibitor VIII	JNK	10	23	2.30258509299405	NA	4.74015146844361	4.31242080684626	0.427730661597353	0.815676875186563	1.06286838232182	0.428830978601735	0.524387382564355	0.402430506647475	0.373300849000143	NA	NA	0.371486254823247	0.221527525607912	75.9448839654841
a4661	SMAD4_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	0.765905108782468	1.27814961577239	-0.51224450698992	1.89229000506945	1.14452563019766	0.414166295192011	0.270700846919666	0.447560538160647	0.373339822259416	NA	NA	0.263531371346174	0.630728726033237	75.9448839654841
a4662	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1248	FK866	NAMPT	3	29	0	NA	-0.00999562715073895	-1.88405038255659	1.87405475540585	4.01603927448289	2.60582740846299	0.688317213132381	0.46664253691771	0.719178388146295	0.373402784976648	NA	NA	0.0430904687656431	0.505823552365527	75.9448839654841
a4663	gain_cnaOV51_(MYC)	1241	CHIR-99021	GSK3B	8	24	2.30258509299405	NA	3.41372472439677	3.77069419720784	-0.356969472811074	1.02629373801344	1.05658018171453	0.340103237700024	0.347823882762891	0.337853651799351	0.37344197747578	NA	NA	0.829722602180542	0.413813680113473	75.9448839654841
a4664	loss_cnaOV39	1031	Elesclomol	HSP70	10	21	-1.6094379124341	NA	-4.4266775553613	-3.88505644081934	-0.541621114541959	1.75334070359605	1.39457919245661	0.357496743460753	0.308908082400135	0.388376018709897	0.373615102187426	NA	NA	0.863030119906681	0.405605369105109	75.9448839654841
a4665	gain_cnaOV96	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-3.32874777911097	-4.15678267710246	0.828034897991488	0.57328281682576	1.97435550620922	0.458031765851335	1.44437417918136	0.419395035690063	0.373716537443428	NA	NA	0.585247870104332	0.175381416662205	75.9448839654841
a4666	loss_cnaOV82	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.33941600107563	3.74528827657091	0.594127724504717	1.76939010002222	0.948815578569758	0.580099313206104	0.335781083265502	0.6261782984216	0.373763237346728	NA	NA	0.715150334784267	0.621499704510675	75.9448839654841
a4667	gain_cnaOV49	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	0.290682778716364	1.39325942878873	-1.10257665007237	0.760641646657903	2.3957888187812	0.474661493133778	1.44953494844366	0.460214456895777	0.373798678507981	NA	NA	0.359912028402666	0.117565232731223	75.9448839654841
a4668	NF1_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	1.03273024897456	0.496517399603882	0.536212849370679	0.0843501893496722	1.27597751396867	0.443707791375057	6.35698453678412	0.420236911309586	0.373821510226429	NA	NA	0.427356712686564	0.040370658728947	75.9448839654841
a4669	gain_cnaOV94	309	Y-39983	ROCK	7	25	2.99573227355399	NA	5.40445680481375	4.84104277779508	0.563414027018666	1.59340106150664	1.11277021533314	0.460272486370373	0.353592099710245	0.506316595515629	0.373824150081081	NA	NA	0.369039035317543	0.406702342175606	75.9448839654841
a4670	NF1_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.48717637639812	5.74763013627204	-0.260453759873926	0.116219635414274	0.49774516473473	0.549909089350898	2.24104781387	0.523267282792659	0.374046533712902	NA	NA	0.378189211315163	0.0276843613338	75.9448839654841
a4671	loss_cnaOV40	1175	AG-014699	PARP1, PARP2	8	25	1.6094379124341	NA	4.26986291132632	3.78317233921204	0.486690572114278	1.4519552503432	0.917328316622898	0.458343948177046	0.335196674965871	0.530552217014304	0.374207988518453	NA	NA	0.312963829465264	0.395577821589588	75.9448839654841
a4672	loss_cnaOV54	1248	FK866	NAMPT	10	22	0	NA	-0.700984584470464	-2.16625464231312	1.46527005784266	2.32177434745717	2.83396552738993	0.544595551310305	0.631099253658066	0.517038772589506	0.374335608479988	NA	NA	0.0431009968258773	0.1381397940835	75.9448839654841
a4673	loss_cnaOV54	1050	ZM-447439	AURKB	6	16	1.38629436111989	0.693147180559945	2.21201244380366	2.53711877559999	-0.325106331796329	1.57442838039844	1.6003063581321	0.203972128389747	0.206491661255531	0.203152558973644	0.374421372891899	NA	NA	0.222314158548708	0.67754160661338	75.9448839654841
a4674	gain_cnaOV19	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	1.01513530309489	0.601024208783882	0.414111094311008	0.162874614054179	0.629615680021724	0.679184008322551	2.54251466206549	0.657720427637254	0.374506487289198	NA	NA	0.0144248951585212	0.0184543934296418	75.9448839654841
a4675	loss_cnaOV36	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.81437731877512	4.35581068922201	0.458566629553116	1.64360956862035	0.773616270739052	0.53518975000633	0.27899973224057	0.592757219435208	0.374749946696845	NA	NA	0.868584154686128	0.678023500258102	75.9448839654841
a4676	PIK3CA_mut	262	VX-11e	ERK	6	26	1.63315443905142	NA	3.36733422384063	2.7420337480954	0.625300475745226	1.23092130031524	1.07325121545016	0.567887838533896	0.507993870595208	0.582622657904892	0.374805952105092	NA	NA	0.387276152327256	0.289498453663128	75.9448839654841
a4677	loss_cnaOV21, loss_cnaOV22	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.5622976485964	2.74768906337976	0.814608585216645	1.36836237611525	1.38821908554589	0.587357522449265	0.595316415765024	0.586801171153985	0.374916614310596	NA	NA	0.62488442092729	0.413710339825397	75.9448839654841
a4678	loss_cnaOV34	281	CH5424802	ALK	5	27	1.63315443905142	NA	3.66092471357192	3.97699101505498	-0.316066301483065	1.06837425075249	0.657724231372143	0.435338655035793	0.295838561497011	0.480545320374906	0.37505312161317	NA	NA	0.955458027308249	0.553139984376502	75.9448839654841
a4679	loss_cnaOV16, loss_cnaOV17	290	KIN001-260	IKK	6	25	2.99573227355399	NA	4.5827957510598	4.91443458202913	-0.331638830969336	1.07038568419971	0.859504309774289	0.368734348046454	0.309831153260696	0.385848944790546	0.375069647382058	NA	NA	0.6629310496431	0.504072755513479	75.9448839654841
a4680	loss_cnaOV42	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	4.03384068958175	3.49604954544908	0.537791144132669	1.7278112001224	0.768322133136927	0.593134004955795	0.31125573447757	0.699955293409237	0.375135685587398	NA	NA	0.140140534271455	0.58042369421044	75.9448839654841
a4681	loss_cnaOV54	1241	CHIR-99021	GSK3B	10	22	2.30258509299405	NA	3.93954460126306	3.56413693252417	0.375407668738893	1.23729563354724	0.952861087918505	0.35878111301042	0.303409838813239	0.39397943047392	0.375137849820688	NA	NA	0.829739070080681	0.408736958307806	75.9448839654841
a4682	gain_cnaOV51_(MYC)	263	FR-180204	ERK	8	24	2.99573227355399	NA	4.99955942133804	4.74916717467289	0.250392246665158	0.959051479665779	0.666409465612593	0.336076343789455	0.26108321813175	0.375733328509953	0.375141689291994	NA	NA	0.763507489449398	0.509732292161362	75.9448839654841
a4683	SMARCA4_mut	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.01318329599017	3.52864989670274	-0.515466600712569	1.58146621776864	0.832203583507098	0.573010096622902	0.325942214206677	0.619399640818986	0.375150193898389	NA	NA	0.792762973965068	0.630972954968953	75.9448839654841
a4684	loss_cnaOV54	1170	CCT018159	HSP90	11	22	2.30258509299405	NA	4.06703239990493	3.50892248812435	0.558109911780579	1.10401038595382	1.24879736357651	0.463548061548604	0.505529584577589	0.446917913233074	0.375179779923322	NA	NA	0.195034410559731	0.20362976039214	75.9448839654841
a4685	loss_cnaOV54	268	YM155	BIRC5 (Survivin)	10	20	1.63315443905142	NA	-4.6978832668014	-3.87779481761257	-0.820088449188829	0.944157132198493	2.75647103929731	0.351532240263017	0.868593183508801	0.297513900018297	0.375234141677928	NA	NA	0.927466270798286	0.241963236081785	75.9448839654841
a4686	NF1_mut	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	5.46000117303435	5.15234194955437	0.307659223479981	0.260052001721964	0.807620166495924	0.399258554120843	1.18306808424	0.380945444706814	0.375242083880833	NA	NA	0.33006708181894	0.147195288613019	75.9448839654841
a4687	loss_cnaOV33_(ZFHX3)	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	-0.129744658003222	1.0062242966421	-1.13596895464532	0.246655538829089	2.17410496280979	0.552535047183928	4.60548731254096	0.522499591361591	0.375264134077151	NA	NA	0.412270531829385	0.0162349244994459	75.9448839654841
a4688	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.79378482860003	4.17287842671137	0.620906401888659	1.59372075179265	0.910198983867625	0.640797753406457	0.389595480381522	0.682165562578743	0.375497255076608	NA	NA	0.206404047247536	0.571231168743385	75.9448839654841
a4689	loss_cnaOV41	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.99635683927903	5.67649611763984	0.319860721639187	0.875249286816868	0.542245362550714	0.535360778935274	0.365450993741984	0.589881894304392	0.375499204647934	NA	NA	0.189148138128291	0.468606152430481	75.9448839654841
a4690	ARID1A_mut	1164	XMD8-92	MAP2K5 (ERK5)	6	17	2.30258509299405	NA	2.93113639138057	2.91944030042498	0.0116960909555854	0.97284641387608	0.82487799260921	0.0135620313983619	0.0120225461992352	0.0141791768726778	0.375556860192801	NA	NA	0.324784498756665	0.979685895585599	75.9448839654841
a4691	loss_cnaOV81_(RB1)	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	3.69620518548208	2.42881081407249	1.26739437140959	2.47383139745234	2.29497602572251	0.547829351638861	0.512320432473614	0.552247325115556	0.375576545500265	NA	NA	0.382486579479886	0.391337942858725	75.9448839654841
a4692	loss_cnaOV43_(NF1)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.84295132412161	1.26537130028936	0.577580023832249	1.23721573923895	1.36094359534019	0.428258765012762	0.466838567853602	0.424396739005096	0.375605228328281	NA	NA	0.577943645517615	0.43667242611583	75.9448839654841
a4693	loss_cnaOV20	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.21589182789864	2.57287767252295	-0.356985844624305	0.551163976633231	1.08410800551226	0.343205763503088	0.647694442595728	0.329289925735418	0.375630631591291	NA	NA	0.192232147744258	0.337747585423839	75.9448839654841
a4694	loss_cnaOV16, loss_cnaOV17	344	THZ-2-49	CDK9	6	26	2.99573227355399	NA	3.48388325533696	2.3803163078437	1.10356694749326	2.1813307827332	2.33632319255029	0.477483870430373	0.505914534479954	0.472352006354321	0.375840543869815	NA	NA	0.382493727370553	0.302978797238296	75.9711357830002
a4695	SMAD4_mut	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	2.30736325256671	1.46815777167946	0.83920548088725	1.14090044686094	1.24686791368014	0.678328437979911	0.735564161795388	0.673050827340908	0.376170328182019	NA	NA	0.15956931476664	0.331598097496288	76.0062677043387
a4696	gain_cnaOV19	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.93481213422705	3.26213117114485	0.672680963082201	1.80007422466641	1.17212167215296	0.549553988027667	0.373696236446507	0.573900286176447	0.376174557355676	NA	NA	0.993564150683612	0.586475000834749	76.0062677043387
a4697	loss_cnaOV59	308	XL-880	MET	4	28	1.63315443905142	NA	0.596270442507823	0.204073823308515	0.392196619199308	0.218102211367865	1.01983053377556	0.404346665201275	1.79822394619285	0.384570383225673	0.376465149351939	NA	NA	0.364805202848734	0.0889982218535231	76.0487875948863
a4698	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	1.14388918553438	0.480049409002428	0.663839776531947	1.64968924451446	1.13771732967107	0.552810477704919	0.402402924514023	0.583483928054318	0.376694940148879	NA	NA	0.42743529839897	0.486705452327981	76.0547552990492
a4699	loss_cnaOV21, loss_cnaOV22	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.58760621373633	2.92640028759684	0.661205926139487	0.161141066136772	1.02808251092215	0.664389888643154	4.10327387047491	0.64314480512504	0.376704564723245	NA	NA	0.0855786279738732	0.00426955722314735	76.0547552990492
a4700	gain_cnaOV18_(CCNE1)	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.42567923929456	3.8288101659908	0.596869073303762	1.09724310731017	1.06107190607889	0.560637295908545	0.543971585993328	0.562515197965653	0.376783870503246	NA	NA	0.313032137386708	0.366326764979837	76.0547552990492
a4701	loss_cnaOV16, loss_cnaOV17	1018	ABT-888	PARP1, PARP2	6	25	1.6094379124341	NA	4.63125056111828	4.21998509128102	0.411265469837261	0.881727786587239	0.770064577793668	0.52029740624827	0.466431336398141	0.534066209116628	0.37681531701206	NA	NA	0.221666474311528	0.328676896455814	76.0547552990492
a4702	PIK3CA_mut	203	BMS-345541	IKBKB	6	26	2.77258872223978	NA	2.64561413531882	3.42170861634748	-0.776094481028655	0.4792541986676	1.07669247064794	0.774417233723726	1.61937961771919	0.720813511922868	0.376936763523162	NA	NA	0.0896695540050394	0.0145697908967627	76.0630873386022
a4703	loss_cnaOV35	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	2.05048999486338	2.5117190854994	-0.461229090636021	2.53043154314409	1.21435194869633	0.315897363581252	0.182272898030246	0.379815004316643	0.377097951493305	NA	NA	0.236757212114491	0.708621199197785	76.0677075037249
a4704	gain_cnaOV48_(SOX17)	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	1.64682949819982	2.34788952291483	-0.701060024715016	2.18721198166033	1.76276406439564	0.390958621656754	0.320526785054842	0.397704967372008	0.377119999259767	NA	NA	0.108137570618745	0.638777932396739	76.0677075037249
a4705	loss_cnaOV83	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-0.992372978066983	-1.72691065092427	0.73453767285729	1.81721076286081	1.14833729440085	0.568620027476196	0.404211601576098	0.639653241637978	0.377384225022302	NA	NA	0.617282430567154	0.488692758933188	76.1048249174608
a4706	loss_cnaOV42	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.25896425910696	3.74180719613337	-0.482842937026417	0.788670080196341	1.07379306390269	0.460387652498377	0.612224235647702	0.449661069025282	0.377664217650246	NA	NA	0.82976340689296	0.328269409483528	76.1209760419965
a4707	gain_cnaOV50	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	1.64457578821125	2.39001140046804	-0.74543561225679	1.01113968200763	1.43748349581122	0.532676444855376	0.737223180457833	0.518569857969823	0.377748737640951	NA	NA	0.526825028265208	0.252235577628258	76.1209760419965
a4708	gain_cnaOV51_(MYC)	225	Genentech Cpd 10	AURKA, AURKB	8	24	2.32630161961136	NA	2.46920143988555	2.96913619710902	-0.49993475722346	1.51448815453715	1.94667181156552	0.269527251886461	0.330101464132116	0.256815121199814	0.377938406121182	NA	NA	0.342863563092852	0.464688979564278	76.1209760419965
a4709	loss_cnaOV54	208	SB-715992	KIF11	10	22	-2.05572501506252	NA	-1.5007062297072	-1.23407761201751	-0.266628617689687	1.37689313165274	2.062194109842	0.141599524281834	0.193645106915191	0.129293656895429	0.377998320533771	NA	NA	0.0721486437934878	0.670179577825014	76.1209760419965
a4710	loss_cnaOV84	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	4.16128780787846	3.76811972181708	0.393168086061383	1.02305705437728	0.839257934665678	0.448186922003195	0.384307096441165	0.468471097884827	0.378098906584866	NA	NA	0.939218693784723	0.462379487256142	76.1209760419965
a4711	loss_cnaOV85	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	4.16128780787846	3.76811972181708	0.393168086061383	1.02305705437728	0.839257934665678	0.448186922003195	0.384307096441165	0.468471097884827	0.378098906584866	NA	NA	0.939218693784723	0.462379487256142	76.1209760419965
a4712	loss_cnaOV21, loss_cnaOV22	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	0.490106699760729	1.53423492052729	-1.04412822076657	1.13072093288583	1.81576283040897	0.587573497578378	0.923418140054894	0.575035573633477	0.378127543444613	NA	NA	0.611973086005572	0.245416069801266	76.1209760419965
a4713	loss_cnaOV16, loss_cnaOV17	1011	ABT-263	BCL2, BCL2L1, BCL2L2	6	27	0.693147180559945	NA	2.12865812387688	1.65092852843077	0.477729595446113	1.53103589580677	1.73550161656138	0.280327581626236	0.312030303635941	0.275268885310898	0.378182428642488	NA	NA	0.226077949006573	0.518933848577821	76.1209760419965
a4714	gain_cnaOV94	193	GW-2580	CSF1R (cFMS)	7	25	2.99573227355399	NA	5.95366399403021	5.66286125657837	0.290802737451841	0.553993886685257	0.606792221755859	0.487428061551996	0.52492048096743	0.479245987383215	0.378336241399625	NA	NA	0.189218055922629	0.256138154127017	76.1209760419965
a4715	loss_cnaOV52, loss_cnaOV53	288	KIN001-055	JAK3, MNK1	8	24	2.32630161961136	NA	3.54842344902838	3.88517585131484	-0.336752402286467	1.11098250810145	1.00234091548454	0.327351720418304	0.303112245090106	0.335965934428285	0.37842060298935	NA	NA	0.715223208856816	0.462932318712476	76.1209760419965
a4716	gain_cnaOV48_(SOX17)	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	3.94876463016013	4.43257974350793	-0.483815113347793	0.70923728756946	0.999511258430152	0.492267106211244	0.682162545353215	0.484051689530422	0.378548429733563	NA	NA	0.508432279656339	0.363203940746165	76.1209760419965
a4717	gain_cnaOV51_(MYC)	282	EKB-569	EGFR	8	24	0.916290731874155	2.99573227355399	1.3883132251042	1.78203990420328	-0.393726679099077	1.94953261677995	1.31278148075219	0.26496348408665	0.201959523893167	0.299917910841857	0.378615993163877	NA	NA	0.322984674477219	0.607045338355591	76.1209760419965
a4718	loss_cnaOV55	1001	AICAR	AAPK1 (AMPK) agonist	7	24	7.60090245954208	NA	9.17085375134987	8.62671088141177	0.544142869938094	0.517663166548208	1.34783566065924	0.444848208657292	1.05115238073911	0.403716035879291	0.378779140673185	NA	NA	0.526849832846387	0.118933808159086	76.1209760419965
a4719	PIK3CA_mut	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	1.2692928202668	1.80866024981908	-0.539367429552285	2.14323071856469	2.39671998950804	0.230543462946634	0.251660927066917	0.225043990083713	0.378989966879441	NA	NA	0.608612962594165	0.652535106185375	76.1209760419965
a4720	loss_cnaOV87, loss_cnaOV88	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.70378022170066	4.09571619707371	0.608064024626954	1.79553971505697	0.946117409026915	0.594718155437619	0.338652506278682	0.642694044973076	0.379027640747292	NA	NA	0.526823614492812	0.618592075963371	76.1209760419965
a4721	loss_cnaOV81_(RB1)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.1139685062628	2.23769346189518	0.876275044367621	1.3299000704447	1.55828808123294	0.569872244136857	0.658902923491543	0.562331865924495	0.379190219639605	NA	NA	0.238951724447314	0.290129421416344	76.1209760419965
a4722	loss_cnaOV52, loss_cnaOV53	1026	17-AAG	HSP90	9	24	0	NA	0.321659105557184	-0.850516382232761	1.17217548778995	2.61398043174503	2.11170063662428	0.520487733123329	0.448425502178465	0.555086013358295	0.379196129189594	NA	NA	0.059592817212024	0.250868653195058	76.1209760419965
a4723	loss_cnaOV44	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.73980859533068	2.94682834205948	0.792980253271206	1.51964825356729	1.14860456267335	0.673185531416406	0.521818290127157	0.690385776829547	0.379210244266225	NA	NA	0.0863093189082305	0.46376436001606	76.1209760419965
a4724	loss_cnaOV42	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.24682012390016	5.9058986206568	0.340921503243354	1.04137991317862	0.651635412863642	0.487785616034779	0.327374763934859	0.523178293434298	0.379251652365644	NA	NA	0.90806226502669	0.564785398631707	76.1209760419965
a4725	gain_cnaOV95_(MECOM)	134	Etoposide	TOP2	5	14	2.77258872223978	NA	3.01655436953681	2.02143808764286	0.995116281893956	0.829920637101508	1.99993327775866	0.554497855921316	1.19904993008656	0.497574740597942	0.379265657317914	NA	NA	0.402936840128716	0.145418562163121	76.1209760419965
a4726	PIK3CA_mut	294	MPS-1-IN-1	MPS1	6	25	2.99573227355399	NA	4.67403703783772	4.19020419107461	0.483832846763117	0.860898395501465	0.78920314193336	0.603266476659143	0.562009232786744	0.613065028577866	0.379317881859968	NA	NA	0.313316218150359	0.248615059729057	76.1209760419965
a4727	loss_cnaOV52, loss_cnaOV53	275	I-BET	BRD2, BRD3, BRD4	8	23	2.99573227355399	NA	4.21286996026955	3.81794016385581	0.394929796413741	0.842484992890368	1.31602183297272	0.324062386599708	0.468767752240701	0.300093650818577	0.379326313342746	NA	NA	0.696611773515035	0.341455371118491	76.1209760419965
a4728	loss_cnaOV36	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	4.78459018756182	3.75760056233818	1.02698962522363	1.63224330673364	1.46024038221683	0.695093298462363	0.629189055937249	0.703301756156429	0.379432277218269	NA	NA	0.0669612344439291	0.392134244937766	76.1209760419965
a4729	loss_cnaOV58	1032	Afatinib	ERBB2, EGFR	5	26	-0.693147180559945	NA	0.993147338519852	0.234778231939696	0.758369106580156	1.65160655877145	1.66713334469154	0.455476851304453	0.459170558843185	0.454894090502685	0.379459893022025	NA	NA	0.836009177764574	0.385945779867707	76.1209760419965
a4730	PIK3R1_mut	158	PF-562271	FAK	3	15	0.940007258491471	NA	1.72664017828972	2.40199976392452	-0.675359585634798	1.87164601673649	1.30498236641019	0.486387939298283	0.360837241441838	0.517523916811694	0.379515991893462	NA	NA	0.743415004969163	0.602145793217252	76.1209760419965
a4731	loss_cnaOV38	303	PIK-93	PI4K, PI3K	8	24	2.99573227355399	NA	2.47572820287737	3.04852117372971	-0.57279297085234	0.548182915481732	1.37374919608148	0.465061594046016	1.04489387515658	0.416956000765053	0.379550195728168	NA	NA	0.228327295765736	0.103740739095402	76.1209760419965
a4732	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.38891356820141	2.06645475930797	0.322458808893441	0.525441218866301	0.5545194796828	0.585380121594819	0.613691498335784	0.581510335900006	0.37978373570282	NA	NA	0.0410022227642698	0.258932012568219	76.1348959814817
a4733	loss_cnaOV35	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	4.60091543252744	3.69451136926733	0.906404063260116	1.29244105147458	1.50874192289553	0.616602404226999	0.701311724992004	0.600768129727961	0.379791449705783	NA	NA	0.066968716300942	0.221527410305357	76.1348959814817
a4734	PTEN_mut	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-2.19385824499144	-2.78787173026216	0.594013485270717	0.618646928570413	1.82912196170481	0.334786674187682	0.960181741536131	0.324753350354546	0.37986032519919	NA	NA	0.694195012101847	0.268105383530804	76.1348959814817
a4735	gain_cnaOV19	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.02291037473211	2.14463587190548	0.878274502826626	1.26343169822346	1.88429797691331	0.481967925853574	0.695149966604121	0.466101706623565	0.379951124839044	NA	NA	0.402969766224264	0.370026074781134	76.1370118126578
a4736	loss_cnaOV54	1036	PLX4720	BRAF	11	22	2.30258509299405	NA	4.66948746659782	4.12709215275476	0.542395313843056	1.10555887521473	1.37468200952324	0.419162357048452	0.490607353441677	0.39456056752439	0.38004716071288	NA	NA	0.367818868623665	0.233349879706715	76.1401757984874
a4737	loss_cnaOV44	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.27363268125678	2.75028958935973	0.523343091897048	1.53702177749371	0.903951431720679	0.546566692022511	0.340491657021555	0.57895045411993	0.38040642230191	NA	NA	0.965959528882276	0.617252813704473	76.1531087405049
a4738	gain_cnaOV94	298	OSI-930	KIT, VEGFR, PDGFR	7	25	2.32630161961136	NA	4.85934900662629	4.33738691542899	0.521962091197299	0.431405029786783	1.05938981711386	0.539780863858267	1.20991192767334	0.492700687476212	0.380511302201477	NA	NA	0.0301967098109483	0.0620422246802239	76.1531087405049
a4739	loss_cnaOV21, loss_cnaOV22	304	SB52334	ALK5	3	29	2.99573227355399	NA	3.78480196615179	4.4268306670802	-0.642028700928408	0.944651340048993	1.06097347343432	0.609356077794356	0.679646207769218	0.605131718185368	0.380535599998192	NA	NA	0.34842775581262	0.361542359614683	76.1531087405049
a4740	gain_cnaOV50	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	5.08541308843592	4.75359321422116	0.331819874214764	0.704505899351031	0.654924805221343	0.502718894106365	0.470996587140613	0.506653392220531	0.380601293979298	NA	NA	0.760443934726265	0.427080497378028	76.1531087405049
a4741	loss_cnaOV40	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	4.56045635972038	3.71070556526697	0.849750794453409	2.14620020212913	1.54913915380414	0.50279202825919	0.395932678419477	0.548530964675911	0.380624829013992	NA	NA	0.14441087121479	0.357946820483757	76.1531087405049
a4742	SMAD4_mut	310	YM201636	FYV1	3	29	1.63315443905142	NA	1.90518488890586	2.40364743530005	-0.498462546394188	1.01330054380847	0.850003603990033	0.578361318707642	0.491919746258819	0.586424038738585	0.380715489307394	NA	NA	0.648237583021099	0.487235782575141	76.1531087405049
a4743	loss_cnaOV43_(NF1)	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.47605871373433	2.99496332437596	0.481095389358368	0.911493266757586	0.908525469475179	0.529310869258861	0.527810140682385	0.529534289926157	0.380767435345885	NA	NA	0.235717040370664	0.321938127620853	76.1531087405049
a4744	SMARCA4_mut	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.78747188528445	4.34581692401231	0.441654961272142	1.13498689958319	0.972999078188841	0.448550201419956	0.389127805293906	0.453910976045575	0.380802195008803	NA	NA	0.50848615428907	0.574447270778411	76.1531087405049
a4745	ARID1A_mut	1069	EHT 1864	Rac GTPases	9	24	2.30258509299405	NA	3.80881542814032	4.3870153514116	-0.57819992327128	1.02762785964083	0.921254569448065	0.608729615144256	0.562654970714176	0.627622312492504	0.38083405505779	NA	NA	0.206534191891183	0.162548115338277	76.1531087405049
a4746	gain_cnaOV96	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	1.13950578792154	0.480698801241367	0.658806986680171	0.668556943103424	1.24809282471333	0.54846738192741	0.985416415873278	0.527850952777883	0.380942055954007	NA	NA	0.427549912983055	0.155487298551979	76.1586547378693
a4747	loss_cnaOV70	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.621851600949751	1.41683127148035	-0.794979670530601	0.526952488237738	1.38300294854716	0.592553185407088	1.50863633491743	0.574821385135675	0.381036257593097	NA	NA	0.578065163137604	0.0963407884793027	76.161440206236
a4748	gain_cnaOV19	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-3.43126865405316	-4.26125599872596	0.8299873446728	1.23367887322216	1.33352468543583	0.625413366095271	0.672774222440084	0.622401185173066	0.381244294583531	NA	NA	0.21455245615978	0.36529613025868	76.1706349691484
a4749	loss_cnaOV20	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.66805721082718	4.15097932975019	0.517077881076986	1.13149468268869	0.940868599562343	0.534404259514574	0.456986576241163	0.549575021759161	0.381269759364823	NA	NA	0.206544704505404	0.378978605581949	76.1706349691484
a4750	loss_cnaOV55	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	2.71961920515305	2.31350564856218	0.406113556590869	0.551439834495432	1.0529208037668	0.413057234725981	0.736460319306572	0.385701901926533	0.381378915555764	NA	NA	0.404108645451965	0.319680062820586	76.1706349691484
a4751	gain_cnaOV18_(CCNE1)	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	2.62809244544574	3.4818165895476	-0.853724144101866	1.92708181813723	1.62434739287606	0.515188119169606	0.443013958238213	0.525579779206138	0.381452535365426	NA	NA	0.627339974920423	0.450501332900552	76.1706349691484
a4752	loss_cnaOV52, loss_cnaOV53	1018	ABT-888	PARP1, PARP2	8	23	1.6094379124341	NA	4.58393282754065	4.20068121862652	0.383251608914127	0.745580809523605	0.802682222658934	0.485572735980589	0.514030946100944	0.477463681261785	0.381504279058871	NA	NA	0.221790902501394	0.241269109660377	76.1706349691484
a4753	loss_cnaOV84	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	1.98587496469081	2.42988950872823	-0.444014544037421	0.867837219519225	1.31970474454758	0.361449153373384	0.511633442367684	0.336449911142539	0.381822133431487	NA	NA	0.38310946332211	0.415190866378935	76.1706349691484
a4754	PIK3R1_mut	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.74463050949915	2.46752112639888	0.277109383100269	0.157504335365344	0.669628940706476	0.442639895225591	1.75937622578764	0.413825278829663	0.381839283529311	NA	NA	0.857109420917585	0.069682911930986	76.1706349691484
a4755	gain_cnaOV18_(CCNE1)	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	3.28016995783649	2.2636275133931	1.01654244444339	1.40917269146833	1.57051578742068	0.656941244334654	0.721375350656396	0.647266619403359	0.381849811223313	NA	NA	0.222604698561856	0.259590494823197	76.1706349691484
a4756	loss_cnaOV1	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	2.00608094631626	1.57396319078183	0.432117755534431	0.676446718947533	0.676988220925396	0.638328374576692	0.638805309318008	0.638294348672353	0.3818636899621	NA	NA	0.205934405485743	0.385418244185016	76.1706349691484
a4757	loss_cnaOV83	1007	Docetaxel	Microtubules	5	26	-4.38202663467388	NA	-3.98658204171709	-4.77588132081542	0.789299279098337	1.9045890860796	1.30284143820066	0.563266499320256	0.4144197217485	0.60582911776926	0.381885044523559	NA	NA	0.132698964667359	0.417463458523878	76.1706349691484
a4758	gain_cnaOV94	346	THZ-2-102-1	CDK7	7	25	0.916290731874155	2.99573227355399	-1.73704013409766	-0.869684082456564	-0.867356051641092	0.853028487168358	2.14350043159393	0.443707880384962	1.01679611488743	0.404644682528064	0.381978888739454	NA	NA	0.440395975646245	0.118046144159204	76.1733402033884
a4759	SMAD4_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	-0.0765086778346558	-0.661791474981438	0.585282797146782	2.84890950910276	1.7048208254341	0.31198602524628	0.205440992518963	0.343310445540662	0.382121635875112	NA	NA	0.040311554821337	0.759768476075594	76.1857943578878
a4760	gain_cnaOV50	326	GSK690693	AKT	4	28	2.32630161961136	NA	3.73879199705383	4.21095102752765	-0.472159030473821	0.908433419203288	1.51007903797859	0.323151857049999	0.51975083753294	0.312671733464931	0.382257307070339	NA	NA	0.0913733663287222	0.414103330291542	76.1938084075212
a4761	gain_cnaOV48_(SOX17)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.33028774321894	2.84462408316351	-0.514336339944575	0.61898918423126	0.976990163832937	0.536919551491783	0.830929446018259	0.52644986509048	0.382478496449055	NA	NA	0.965963372300766	0.285365507240374	76.1938084075212
a4762	loss_cnaOV34	1053	MK-2206	AKT1, AKT2	5	27	1.38629436111989	0.693147180559945	1.88468713752697	1.203447957463	0.681239180063969	1.12197791058444	1.21274899837368	0.56720649977814	0.607176998439397	0.561731389576509	0.382486317652042	NA	NA	0.0952748839979372	0.265299732253131	76.1938084075212
a4763	loss_cnaOV36	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.51273412377821	5.73600506723707	-0.223270943458858	0.660195657730658	0.461362819375138	0.467874354581237	0.33818905175221	0.483937877268161	0.382552695021769	NA	NA	0.378417726031036	0.620522820501018	76.1938084075212
a4764	loss_cnaOV35	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.65569249774638	4.11209375397619	0.543598743770194	1.31097823953032	0.894409304894486	0.565984431554168	0.414651233238584	0.607774025600419	0.382751922838215	NA	NA	0.0466831496272895	0.416745258581808	76.1938084075212
a4765	loss_cnaOV85	1170	CCT018159	HSP90	7	26	2.30258509299405	NA	4.16162491530089	3.56931833579168	0.592306579509205	1.50725338722293	1.12527820073022	0.490049439942344	0.392970806720504	0.526364572889482	0.382806248339768	NA	NA	0.195216621010781	0.361060295704294	76.1938084075212
a4766	gain_cnaOV72_(ASXL1)	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	4.06356437942781	3.61069024559346	0.452874133834352	0.935852221575152	1.06419546641002	0.432135287355938	0.483916288697922	0.425555406059084	0.382829183837654	NA	NA	0.829812444634518	0.368079305896692	76.1938084075212
a4767	loss_cnaOV35	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.50111488887003	2.84214640062216	-0.341031511752127	1.15138893180513	1.24424967910846	0.276750050698963	0.2961914105058	0.274086075711498	0.382918223950599	NA	NA	0.0925908542289511	0.570568556743129	76.1938084075212
a4768	loss_cnaOV20	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.38766736762991	2.06667729512431	0.3209900725056	0.525035990711124	0.554710204754027	0.582589686806897	0.611367750372391	0.578662641780559	0.382946579701497	NA	NA	0.0410347453671518	0.260586182343358	76.1938084075212
a4769	loss_cnaOV20	263	FR-180204	ERK	5	27	2.99573227355399	NA	5.06753602070276	4.76440027627184	0.303135744430917	0.672962190476231	0.755232855522272	0.407009060066979	0.450449889638523	0.401380504323117	0.382964861275079	NA	NA	0.763609523097273	0.39918180725289	76.1938084075212
a4770	loss_cnaOV34	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.26304141522552	2.83901456921116	-0.575973153985637	1.43536088470411	1.71453402411214	0.342842492411416	0.401274104738036	0.3359356804155	0.383480381166776	NA	NA	0.317989018322853	0.453770299631823	76.1987760016365
a4771	loss_cnaOV42	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	4.52983915891954	3.52007464556438	1.00976451335516	1.37660589130477	2.07344957986455	0.501213134427196	0.733517501075116	0.486997380192444	0.383517957683083	NA	NA	0.745701979069396	0.256343624776599	76.1987760016365
a4772	gain_cnaOV19	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.68165906757158	5.16541946481002	0.516239602761564	0.445040412711845	0.75493323809918	0.710043980492817	1.1599836509585	0.683821531108348	0.383570565144327	NA	NA	0.122215699076735	0.170555976439386	76.1987760016365
a4773	gain_cnaOV51_(MYC)	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	2.76948471973136	2.3297062877398	0.439778431991566	0.247320063474632	0.947504132103913	0.525291525817156	1.77817531587636	0.464144078205809	0.383648677192284	NA	NA	0.617402097178474	0.130494420889023	76.1987760016365
a4774	gain_cnaOV19	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.75420802261951	4.42066437110936	0.333543651510156	0.218042510451584	0.568381970804352	0.604259267579854	1.5297184517797	0.586830104829219	0.383675180242855	NA	NA	0.361558655754672	0.0919751213444492	76.1987760016365
a4775	loss_cnaOV39	298	OSI-930	KIT, VEGFR, PDGFR	9	23	2.32630161961136	NA	4.81469265715611	4.30947313120452	0.505219525951587	0.944372748476452	0.971318420593554	0.523974382193709	0.534978933653744	0.520137902504575	0.38373830231359	NA	NA	0.0302243776132023	0.197054436667944	76.1987760016365
a4776	loss_cnaOV35	1010	Gefitinib	EGFR	5	25	-0.693147180559945	NA	1.38788180006533	0.832934846191423	0.55494695387391	0.903813934330963	1.31308702068197	0.439468976959405	0.614005751399156	0.422627704891708	0.383821563256773	NA	NA	0.957153808253082	0.283441304825338	76.1987760016365
a4777	loss_cnaOV34	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.454634624644573	0.00908918419714868	-0.463723808841721	1.17918724338057	0.917684573352465	0.484716660092505	0.393257145075865	0.505319390024892	0.383823477344064	NA	NA	0.546171700227797	0.442828335027384	76.1987760016365
a4778	gain_cnaOV48_(SOX17)	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	0.348087334631857	0.893449466664802	-0.545362132032945	0.704692272919183	1.38016259707035	0.404918034104338	0.773901109733737	0.395143393387544	0.383916085021817	NA	NA	0.160582076903953	0.321321121867712	76.1987760016365
a4779	gain_cnaOV18_(CCNE1)	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.66719470684102	3.89489822487935	0.772296481961678	0.569912819910519	1.18521759304733	0.669600000442276	1.35511336994128	0.651607339016978	0.383917211521555	NA	NA	0.0807707023904318	0.120697131046785	76.1987760016365
a4780	gain_cnaOV19	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.66719470684102	3.89489822487935	0.772296481961678	0.569912819910519	1.18521759304733	0.669600000442276	1.35511336994128	0.651607339016978	0.383917211521555	NA	NA	0.0807707023904318	0.120697131046785	76.1987760016365
a4781	gain_cnaOV50	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.76541336523701	3.23630231039312	0.529111054843891	1.25257799709488	1.08329349045481	0.480401502233951	0.422417650694061	0.488428167902817	0.384050986897687	NA	NA	0.950584335421685	0.470723556515305	76.1987760016365
a4782	loss_cnaOV58	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.24368213452228	3.59697287375281	0.64670926076947	1.4271438801447	1.17537601570195	0.534114038574094	0.45314930734517	0.55021478414569	0.384104812958725	NA	NA	0.19524714068198	0.382391491782881	76.1987760016365
a4783	loss_cnaOV40	1003	Camptothecin	TOP1	7	24	-2.30258509299405	NA	-3.04226250794295	-3.8804319803623	0.838169472419347	2.12213012895594	1.5788685682592	0.491443777752816	0.394966105510088	0.530867159730389	0.384114144235909	NA	NA	0.241871373520116	0.360492204370477	76.1987760016365
a4784	PTEN_mut	304	SB52334	ALK5	3	29	2.99573227355399	NA	5.09564696659883	4.29122601186154	0.804420954737291	0.366917062079327	1.07563062471093	0.770911385075437	2.19237816355179	0.74785984729049	0.38460935135576	NA	NA	0.348536441163171	0.0289942591756054	76.2810645127789
a4785	loss_cnaOV34	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.44352899562648	1.84597665264072	0.597552342985767	0.826824086229355	1.39610909832112	0.447835408220039	0.722707953164309	0.428012641493669	0.384699776380291	NA	NA	0.837949401121733	0.223665695193816	76.2830534043361
a4786	loss_cnaOV1	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-1.54769046857987	-1.12185819143357	-0.425832277146297	0.756086233414774	1.38307159188092	0.318713903463234	0.563205965572308	0.30788881764767	0.384953693331684	NA	NA	0.0472255203387255	0.466833096005804	76.3174539024364
a4787	gain_cnaOV26	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.63376585892759	4.89503343109623	0.738732427831367	1.15738405283743	1.23237503566221	0.60180976782739	0.638277697036084	0.599438000977045	0.385050496029252	NA	NA	0.369340405078865	0.386234608561931	76.3206984772445
a4788	PIK3CA_mut	1259	BMN-673	PARP1	7	26	2.30258509299405	NA	1.00686815409887	2.14097292846693	-1.13410477436806	1.59605559314158	1.22629434009172	0.868342689778519	0.710567212847363	0.924822644360596	0.38522590773958	NA	NA	0.0331693764935424	0.118847800645444	76.3343063584895
a4789	loss_cnaOV21, loss_cnaOV22	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.58520242878688	3.01612197882793	0.56908044995895	0.285476112227761	0.938547549215336	0.624910920422153	1.9934433235693	0.606341629078596	0.385290534103224	NA	NA	0.23582921002823	0.0435603496253789	76.3343063584895
a4790	loss_cnaOV82	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-3.81821424104122	-4.7375422080951	0.919327967053886	2.47429162527229	1.29132327739254	0.654209173314852	0.371551985895242	0.711927046579854	0.385416653239085	NA	NA	0.132775184603247	0.587537161075043	76.3343063584895
a4791	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	4.35148182818548	3.74890328287467	0.602578545310806	1.54092264455493	1.59361730206867	0.380689995723286	0.391050483578851	0.378119981835413	0.385470569633924	NA	NA	0.7136622757289	0.387471333238294	76.3343063584895
a4792	gain_cnaOV49	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	3.23093121860713	3.59426686401763	-0.363335645410501	1.03468802593387	0.9097248550018	0.395661033162784	0.351154779318693	0.399390698641275	0.385560577841057	NA	NA	0.140358794239447	0.609888643276676	76.3343063584895
a4793	loss_cnaOV83	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.86907168597533	4.36577981471512	0.503291871260203	1.09008610466778	0.986735797455864	0.50295424043046	0.461699189729227	0.510057375599282	0.385601856298755	NA	NA	0.371805146270337	0.377284210038264	76.3343063584895
a4794	loss_cnaOV20	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	1.87848966614923	0.990133777856626	0.888355888292599	2.49008450548169	1.26883921761655	0.571050519524391	0.356757325438943	0.700132748072946	0.385811928672699	NA	NA	0.529368717049429	0.534038315301799	76.3551559418216
a4795	loss_cnaOV33_(ZFHX3)	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	3.0497246680381	2.28661557390728	0.763109094130815	2.1245593966596	1.16854955193552	0.590480275213804	0.359184636273589	0.653039567613411	0.38592583751456	NA	NA	0.107795783260379	0.52857685145342	76.3551559418216
a4796	loss_cnaOV36	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.67050794923203	2.36575013929171	-0.695242190059681	1.89605561049936	1.18756188680346	0.556465581796195	0.366678163978838	0.585436597271619	0.38600053549664	NA	NA	0.843426173870066	0.592878766174999	76.3551559418216
a4797	loss_cnaOV52, loss_cnaOV53	1028	VX-702	p38	8	23	0.693147180559945	NA	3.61623544233415	3.22635488399979	0.389880558334356	1.09503655695202	0.852230294270581	0.425287576274142	0.356043417782845	0.457482632283158	0.386029069799292	NA	NA	0.515134433983223	0.381363454284102	76.3551559418216
a4798	PTEN_mut	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-1.54894250100872	-1.29344628477348	-0.255496216235241	2.61492308533456	1.82251470915505	0.135489293246218	0.0977069718295564	0.140188836310514	0.386313217026717	NA	NA	0.072274785661222	0.882750579558177	76.3775077919538
a4799	loss_cnaOV33_(ZFHX3)	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.64787538034943	2.93107843860221	0.716796941747217	1.26065076214722	1.16661449956925	0.609163307022422	0.568592796093917	0.614424852435728	0.38631838727532	NA	NA	0.0864327418884975	0.347284034570568	76.3775077919538
a4800	loss_cnaOV38	1032	Afatinib	ERBB2, EGFR	8	23	-0.693147180559945	NA	0.823770277485041	0.194774282745696	0.628995994739344	1.11791138087868	1.80542105187852	0.37762614976176	0.562652823379391	0.348392965776531	0.386383563865556	NA	NA	0.836074228328794	0.262644628324482	76.3775077919538
a4801	TP53_mut	269	NSC-207895	MDM4	21	10	2.99573227355399	NA	3.70572431670103	4.26138409355688	-0.555659776855852	1.62997525023407	1.46809125136849	0.351347691466232	0.34090074482791	0.378491307224867	0.386566318644965	NA	NA	0.713679481860992	0.353618511239728	76.3977172436002
a4802	loss_cnaOV56	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.39292373654291	2.29932651909437	1.09359721744855	1.94681402383445	1.50168906599809	0.704656759401495	0.561736870630609	0.728244775972778	0.386828562551574	NA	NA	0.222795048198633	0.436313337972196	76.4179573989771
a4803	gain_cnaOV49	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.51489985007842	5.73578102658532	-0.220881176506908	0.185619319179299	0.491559163576903	0.462768762234367	1.1899686815118	0.449348100642929	0.387092701305263	NA	NA	0.378536763127619	0.169914721145497	76.4179573989771
a4804	loss_cnaOV54	186	Bexarotene	Retinioic acid X family agonist	6	12	2.07944154167984	NA	4.08751059180109	3.6257875142276	0.461723077573491	0.601218237558075	1.09310505422947	0.477646623765295	0.767979160859855	0.422395885726611	0.387230227480678	NA	NA	0.805380738252923	0.265384039896539	76.4179573989771
a4805	loss_cnaOV33_(ZFHX3)	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.29232212629351	2.56721857441441	0.725103551879105	2.14536031213695	1.64451100583524	0.426671128708121	0.337986839682349	0.440923502066091	0.387311521754649	NA	NA	0.637855535725469	0.555743558935832	76.4179573989771
a4806	KRAS_mut	1038	NU-7441	PRKDC (DNAPK)	7	26	0.693147180559945	NA	2.17968170321549	2.63325768376575	-0.453575980550259	0.923818950299715	1.04904536164274	0.442081195442074	0.49097929892335	0.432370226431378	0.387322795446974	NA	NA	0.392078052651381	0.287820305614213	76.4179573989771
a4807	gain_cnaOV94	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.57713407950878	2.301232195301	0.275901884207781	0.732495374027512	0.901006455839598	0.317157935164861	0.376660241129957	0.306215213464462	0.387448349151308	NA	NA	0.60550027310646	0.420412574068125	76.4179573989771
a4808	loss_cnaOV33_(ZFHX3)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.677645985641967	-0.281543817029795	0.959189802671763	2.11562445628791	1.51498364735219	0.604141181385781	0.453383775093413	0.633135416575742	0.387524822239831	NA	NA	0.098316101706654	0.438320802964961	76.4179573989771
a4809	loss_cnaOV59	299	OSI-027	MTORC1/2	4	28	2.99573227355399	NA	2.28231981380602	1.42372874682134	0.858591066984676	0.982320291522613	1.98898021712899	0.448980873737487	0.874043908483092	0.431674010425311	0.387582556966982	NA	NA	0.781166555887421	0.206145680523802	76.4179573989771
a4810	loss_cnaOV33_(ZFHX3)	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.27992768813633	2.81199387012162	0.467933818014717	2.35835930890733	0.913292381222561	0.436485926838143	0.198414981231812	0.512359270301069	0.387586184084576	NA	NA	0.303606744787883	0.764701141291624	76.4179573989771
a4811	loss_cnaOV82	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.27992768813633	2.81199387012162	0.467933818014717	2.35835930890733	0.913292381222561	0.436485926838143	0.198414981231812	0.512359270301069	0.387586184084576	NA	NA	0.303606744787883	0.764701141291624	76.4179573989771
a4812	loss_cnaOV59	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	4.24928373022304	3.7369454679604	0.512338262262644	1.38859701845131	0.976100981306396	0.4999157322586	0.368961084789055	0.524882437447138	0.387784557789275	NA	NA	0.715365915811589	0.521139695254059	76.4179573989771
a4813	gain_cnaOV19	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	3.95792747513054	4.43163186299375	-0.473704387863201	1.08225695447084	0.975822598005607	0.481761013940091	0.437700479452973	0.485441092296244	0.387787930205109	NA	NA	0.508650290816028	0.532250474089277	76.4179573989771
a4814	gain_cnaOV50	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.68170401312229	2.31585454952133	0.365849463600959	1.00231684577502	0.85281046966392	0.4210395544467	0.365003806074988	0.428992697222789	0.387790337757098	NA	NA	0.605507045589881	0.528787386272145	76.4179573989771
a4815	loss_cnaOV82	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.63966807849864	3.65850375877053	0.981164319728113	1.53352200756172	1.54684620287096	0.634651124910914	0.639811046003932	0.634299853409514	0.387832796636737	NA	NA	0.162522615029983	0.384726954561664	76.4179573989771
a4816	loss_cnaOV20	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-2.36143220914129	-2.85015389534126	0.488721686199971	1.09361368222002	1.25193750789384	0.398798518581541	0.446886952994109	0.39037226947706	0.387928355006002	NA	NA	0.373089757488484	0.474398071140732	76.4179573989771
a4817	gain_cnaOV18_(CCNE1)	186	Bexarotene	Retinioic acid X family agonist	4	14	2.07944154167984	NA	4.18497045529183	3.66390227859788	0.521068176693953	1.19313752723066	0.906739691540674	0.538893336971932	0.436720968707926	0.574661263376027	0.387957359516982	NA	NA	0.805395734565883	0.463285501354028	76.4179573989771
a4818	loss_cnaOV57_(ZNRF3)	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	2.6574137478166	2.97829728759167	-0.320883539775073	0.212846542211338	0.917223751835633	0.376188359751254	1.50758164281787	0.349842161340557	0.388104137296428	NA	NA	0.325272312024735	0.188436967273239	76.4231257530755
a4819	gain_cnaOV48_(SOX17)	1026	17-AAG	HSP90	3	30	0	NA	-1.26235272927112	-0.457680101191941	-0.804672628079184	1.95441881323871	2.32538164922579	0.34936365479657	0.411719649150197	0.346038951647825	0.388189422354444	NA	NA	0.0597097181288873	0.558847640613427	76.4231257530755
a4820	loss_cnaOV33_(ZFHX3)	281	CH5424802	ALK	4	28	1.63315443905142	NA	3.63093883855237	3.96998662929052	-0.339047790738157	1.23122041144414	0.646492551340855	0.466710673336456	0.275375381683671	0.524441913576508	0.388244001609241	NA	NA	0.955491119157211	0.623986635940827	76.4231257530755
a4821	gain_cnaOV4_(KRAS)	178	BAY 61-3606	SYK	6	13	2.07944154167984	NA	3.11677379365832	2.52075613210614	0.59601766155218	0.73913873569741	1.49464984829142	0.452150470877311	0.806367780183799	0.3987674184917	0.388357912993967	NA	NA	0.940393811477184	0.261330018325594	76.4231257530755
a4822	RB1_mut	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	5.27120655351011	5.87940298398278	-0.608196430472671	2.30760460563768	1.17757427681061	0.473589595107415	0.26356180299987	0.516482435502868	0.388386321397149	NA	NA	0.568385466067433	0.694465291302377	76.4231257530755
a4823	TP53_mut	185	OSI-906	IGF1R	11	7	0.940007258491471	NA	1.97890672553315	2.56825361321508	-0.589346887681924	1.32188747382196	1.23424212501996	0.456957719290604	0.445837410031546	0.477496980320933	0.388589167606231	NA	NA	0.68194975188525	0.353556575394011	76.4365886408381
a4824	loss_cnaOV41	1262	UNC1215	LMBL3	5	28	0	NA	3.00905454654635	2.73958380418116	0.269470742365191	0.70948953049574	0.446856904479767	0.55135729878458	0.379809328795739	0.603035870462627	0.388615858182574	NA	NA	0.107518848382762	0.45236561794607	76.4365886408381
a4825	loss_cnaOV21, loss_cnaOV22	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	2.36086936177396	2.83313514399402	-0.472265782220053	1.54019889244545	1.20556335840477	0.383735528133496	0.306626491251538	0.391738666348457	0.388778979630742	NA	NA	0.0926919616895008	0.652523206433072	76.4420634568886
a4826	ARID1A_mut	1241	CHIR-99021	GSK3B	9	23	2.30258509299405	NA	3.44546401343486	3.77379488727168	-0.328330873836813	0.872137059873083	1.10846967711807	0.31250010485832	0.37646705884118	0.296201944549756	0.388841721181968	NA	NA	0.829868344537768	0.38795353761164	76.4420634568886
a4827	PTEN_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	3.69930218134436	2.77733268884202	0.921969492502342	1.27030781539243	0.71066511320916	1.21169832224658	0.725784318832616	1.29733326621169	0.388958125177727	NA	NA	0.0187573487644428	0.334918134039159	76.4420634568886
a4828	loss_cnaOV1	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.58187837305126	3.01645438440149	0.565423988649772	0.291223705664108	0.938633595249295	0.620759162531942	1.94154520271753	0.602390529714206	0.388965951476109	NA	NA	0.235918997226295	0.0473437264969551	76.4420634568886
a4829	loss_cnaOV54	282	EKB-569	EGFR	10	22	0.916290731874155	2.99573227355399	1.45527954023796	1.78739400451512	-0.332114464277162	1.77890179827323	1.34402060351918	0.223211463462428	0.186696345239261	0.247105188274313	0.389112894224808	NA	NA	0.323264010628302	0.607147047305023	76.4551058090311
a4830	loss_cnaOV33_(ZFHX3)	304	SB52334	ALK5	4	28	2.99573227355399	NA	3.87105919106646	4.43743780283984	-0.566378611773378	1.33657363148318	1.0172945513886	0.537572547305643	0.423754141509492	0.556749872492952	0.3898249034346	NA	NA	0.348673221149567	0.466938648606276	76.5791472329786
a4831	loss_cnaOV54	308	XL-880	MET	10	22	1.63315443905142	NA	-0.0208886356609456	0.377637962694508	-0.398526598355453	0.570007946179284	1.08554228742663	0.414962123375638	0.699159724047259	0.367122131464998	0.390211591259069	NA	NA	0.36516944513256	0.184710584315352	76.6366786828733
a4832	loss_cnaOV59	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	2.80224738528283	2.21850449719817	0.583742888084651	1.30920142028867	1.41963243358724	0.4144105603414	0.445877066002526	0.411192978037	0.390409811256109	NA	NA	0.527125921899047	0.455485333618234	76.6366786828733
a4833	gain_cnaOV19	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.28168349805271	3.89097691310986	0.390706584942847	0.224003608282083	0.749270880454879	0.53803631559598	1.74419772939925	0.521449044844304	0.390425341189196	NA	NA	0.955496435477691	0.0716846324732366	76.6366786828733
a4834	loss_cnaOV1	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	2.51966922016601	3.46359402167648	-0.943924801510468	2.39175606168411	1.59315641648112	0.569176611700677	0.394657639477589	0.592487210763246	0.390440845240067	NA	NA	0.627511022046332	0.56748408143564	76.6366786828733
a4835	gain_cnaOV50	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	1.79536456602614	2.35157641096344	-0.556211844937304	2.65195998070409	1.67795390393376	0.309788677336445	0.209736138171146	0.33148219604444	0.390670627557677	NA	NA	0.108385022188853	0.707811140498772	76.6383520590408
a4836	gain_cnaOV72_(ASXL1)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	4.59742400094295	3.92810950991499	0.669314491027964	1.15096153999931	1.5343506369523	0.449522094146978	0.58152637405101	0.436220036612643	0.390762927814679	NA	NA	0.326611000658837	0.296783272048136	76.6383520590408
a4837	PIK3CA_mut	221	TAK-715	p38a	6	26	2.99573227355399	2.32630161961136	3.91797322697877	4.36100955998948	-0.443036333010708	0.528268145897659	0.940694409411296	0.500379964893121	0.838658049801355	0.470967328580137	0.390818985417498	NA	NA	0.518825103556516	0.141566671144768	76.6383520590408
a4838	gain_cnaOV50	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-1.64839555670125	-2.18911795892132	0.540722402220068	0.757682698853626	1.33559120293701	0.418833297881208	0.713652829922315	0.404856217254952	0.390821730736724	NA	NA	0.60526925619053	0.277446573145515	76.6383520590408
a4839	TP53_mut	265	Tubastatin A	HDAC6	21	10	2.99573227355399	NA	4.89625165332968	4.46234110757583	0.433910545753855	1.12652742005052	1.4071767812734	0.35550381631985	0.385175307791793	0.308355390401763	0.39095085723019	NA	NA	0.421750637758843	0.407049504460705	76.6383520590408
a4840	gain_cnaOV50	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	3.15103050122753	2.33802654563895	0.81300395558858	1.47303518860135	1.4405220823803	0.563097648662649	0.55192432732074	0.564381459703264	0.391185092608141	NA	NA	0.237117486770159	0.360830373617088	76.6383520590408
a4841	loss_cnaOV87, loss_cnaOV88	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	4.66382769764858	3.54103322822535	1.12279446942323	1.65373761488879	2.03921287530319	0.556994438357889	0.678943539358714	0.550601893025168	0.391236963354847	NA	NA	0.745806409807867	0.362932735601027	76.6383520590408
a4842	KRAS_mut	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	2.99863369022918	3.69712301011035	-0.698489319881168	1.7809659644037	1.67411969573402	0.411656299668843	0.392196894180981	0.417227825263064	0.391246733778525	NA	NA	0.696585975005271	0.378145339977401	76.6383520590408
a4843	loss_cnaOV85	163	JQ1	BRD4	6	13	0.940007258491471	NA	0.549211853687242	-0.124120005872226	0.673331859559468	1.76309504564894	1.89938763993895	0.361940528687069	0.381903324622886	0.354499442557766	0.391404373966232	NA	NA	0.577389122617355	0.46686136410362	76.6383520590408
a4844	loss_cnaOV20	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	2.05139072177472	1.46034937258393	0.591041349190799	1.85494999640028	0.85723077939851	0.558129047077249	0.31862926242636	0.689477516901006	0.391413282698387	NA	NA	0.449832973649797	0.573766293532683	76.6383520590408
a4845	loss_cnaOV36	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.48539300128582	0.805513993568943	0.679879007716873	3.00673600426133	1.00061627111871	0.548364155887579	0.226118623900903	0.679460275972481	0.391476212698442	NA	NA	0.843889432518326	0.733767523163355	76.6383520590408
a4846	loss_cnaOV84	185	OSI-906	IGF1R	4	14	0.940007258491471	NA	1.6549089765685	2.36615095479259	-0.71124197822409	0.832848524665761	1.3712732289003	0.552384679863715	0.853987198343811	0.518672692818829	0.391593475734369	NA	NA	0.682046172317664	0.234449045020092	76.6383520590408
a4847	gain_cnaOV19	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.32646161215928	4.89878319271709	0.427678419442191	0.749553067007369	0.820091291323682	0.524292705346076	0.570577906044358	0.52150098893489	0.391623965314612	NA	NA	0.945636058502252	0.431328886886526	76.6383520590408
a4848	loss_cnaOV54	1033	Vismodegib	SMO	10	21	2.30258509299405	NA	5.18973336356347	4.7781861620743	0.411547201489161	0.750991643571524	0.883083975633175	0.487439430621972	0.548005034426146	0.466034049812851	0.3917257221063	NA	NA	0.151555130708915	0.192959065773957	76.6383520590408
a4849	loss_cnaOV70	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.77799866394696	4.17445704317668	0.603541620770278	0.224134597305993	1.00108235503018	0.622257104953332	2.69276420519011	0.602889080741095	0.391852693553992	NA	NA	0.206794967235214	0.0173593780961152	76.6383520590408
a4850	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	3.37119457711046	2.72126441061858	0.649930166491883	2.31792233023234	1.4065034796901	0.418114703799721	0.280393418715949	0.462089270219996	0.391868341188927	NA	NA	0.968614729890211	0.572709623895199	76.6383520590408
a4851	loss_cnaOV35	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.46855002022159	2.99630416250323	0.472245857718355	1.28719818377606	0.839264564626021	0.519211739396295	0.366878903086236	0.562690095141559	0.391928619218038	NA	NA	0.235990500713991	0.467589739738748	76.6383520590408
a4852	loss_cnaOV52, loss_cnaOV53	312	AV-951	VEGFR	8	24	-2.05572501506252	NA	0.884300683935196	0.558362603855654	0.325938080079542	0.443930111489838	0.646125684464648	0.538721720376094	0.734210344474467	0.504449966804215	0.392029090294446	NA	NA	0.0145118861240738	0.129576139117086	76.6383520590408
a4853	loss_cnaOV1	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	3.97443922202576	4.43980449889694	-0.46536527687118	1.24827905984114	0.822639867013346	0.543328930295992	0.372805482237606	0.565697452228669	0.392160801938223	NA	NA	0.868706780531708	0.587271512660399	76.6383520590408
a4854	loss_cnaOV57_(ZNRF3)	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.03704492414484	4.44721630815194	-0.410171384007104	1.20069843474282	0.810995101095917	0.478896283788064	0.341610659378398	0.505763084700301	0.392354663980461	NA	NA	0.868708101494704	0.549858421130319	76.6383520590408
a4855	loss_cnaOV41	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	3.10645621868059	2.13731761030862	0.969138608371971	1.46347414513809	1.8101498498542	0.547771539687442	0.662217786075427	0.535391370195141	0.392383128435903	NA	NA	0.108415444514538	0.23442520013541	76.6383520590408
a4856	loss_cnaOV43_(NF1)	305	TPCA-1	IKK	5	27	2.99573227355399	NA	2.88613114861718	3.40650313417762	-0.52037198556044	0.932643398325861	1.26426367176738	0.424708685837553	0.557953861566525	0.411600837057182	0.392427493894852	NA	NA	0.993569990652618	0.316623332357372	76.6383520590408
a4857	gain_cnaOV19	1262	UNC1215	LMBL3	3	30	0	NA	3.06600730687077	2.7518532443064	0.314154062564373	0.102672430225243	0.505920368330868	0.641101006887397	3.05977039673826	0.620955553935948	0.39259993497989	NA	NA	0.107589580203771	0.010926586570197	76.6383520590408
a4858	loss_cnaOV21, loss_cnaOV22	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.83348550381851	2.92463474624826	0.908850757570247	1.23477416907536	1.63673725550072	0.563433046139951	0.736046137287453	0.55528201274566	0.392625986273287	NA	NA	0.661410771498783	0.331338510418375	76.6383520590408
a4859	loss_cnaOV84	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	1.6094379124341	NA	0.667527363741538	1.2790619974884	-0.611534633746859	2.12566287297025	1.32692056141095	0.411780997679167	0.287691261640349	0.460867554193747	0.392745880569081	NA	NA	0.811928093793387	0.524638825016779	76.6383520590408
a4860	loss_cnaOV21, loss_cnaOV22	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.49111663653723	4.82651422214912	-0.335397585611881	0.751587955281424	0.655192485801875	0.506600295570459	0.446251943308878	0.511906947774891	0.392797885293505	NA	NA	0.760600431682324	0.524670435362602	76.6383520590408
a4861	loss_cnaOV36	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.73498984658317	3.38625071814249	-0.651260871559319	1.24173243026821	1.22390146782961	0.531598881515172	0.524477621494228	0.532118711087278	0.39285089647471	NA	NA	0.993570138098415	0.463774624853561	76.6383520590408
a4862	gain_cnaOV94	1026	17-AAG	HSP90	7	26	0	NA	0.406814534983654	-0.783275498786815	1.19009003377047	2.64988335582018	2.1566411427726	0.526466802331308	0.449110347123984	0.551825711829126	0.39290408965199	NA	NA	0.0597695278601374	0.304539742809476	76.6383520590408
a4863	loss_cnaOV70	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	2.26755579254648	2.9167219972516	-0.649166204705118	1.2156830553928	1.05174016029371	0.610430561525467	0.533992969487728	0.617230594792376	0.392912555374448	NA	NA	0.303744895698159	0.455507249666505	76.6383520590408
a4864	loss_cnaOV57_(ZNRF3)	272	AR-42	HDAC	4	26	1.63315443905142	NA	0.939973668689251	0.195886098960448	0.744087569728803	2.466775853489	1.75109566546069	0.404147050772728	0.301643770623248	0.424926852601763	0.392944960126704	NA	NA	0.483051345743275	0.596646399007288	76.6383520590408
a4865	loss_cnaOV59	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	3.01854960241403	2.47063011347455	0.547919488939482	1.06556746313	1.02305714126885	0.533385828749833	0.514204410230415	0.53557075830576	0.392953286701306	NA	NA	0.392217095478275	0.390172967445198	76.6383520590408
a4866	loss_cnaOV16, loss_cnaOV17	1133	JNJ-26854165	MDM2	6	27	2.30258509299405	NA	3.43354505914737	2.98659245541905	0.446952603728324	0.876823239120649	0.914976534448001	0.491734302180061	0.509740827782536	0.488485318367173	0.393131946450203	NA	NA	0.236019323387001	0.29658673037402	76.6437518587323
a4867	loss_cnaOV36	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	-0.248254758810373	0.977319161374548	-1.22557392018492	0.0836096184220116	2.13716954744721	0.595068979846367	14.6582886432869	0.573456570934598	0.393142527836293	NA	NA	0.412766377258643	0.0063942411415373	76.6437518587323
a4868	PIK3CA_mut	1026	17-AAG	HSP90	7	26	0	NA	-0.89942580128727	-0.431595408252336	-0.467830393034934	2.45650214337577	2.2698591349568	0.20277307775921	0.19044574998499	0.206105474049092	0.393338600711154	NA	NA	0.0597749900885275	0.660381477193385	76.6512774752853
a4869	gain_cnaOV51_(MYC)	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	3.20855401453766	2.00552750599559	1.20302650854207	1.74806080910618	1.61101125886064	0.732456172946088	0.688206326848091	0.746752390416495	0.393443224518073	NA	NA	0.635339802697455	0.367722733265281	76.6512774752853
a4870	loss_cnaOV44	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.22772605216749	8.80549497345818	-0.577768921290692	0.19620981098731	1.27677465638398	0.468573262698078	2.94464847799105	0.452522235150736	0.393567249306351	NA	NA	0.527198561384981	0.0402154299819345	76.6512774752853
a4871	loss_cnaOV82	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	3.84174826954141	4.33121722125955	-0.489468951718135	0.28465564319757	0.838327276562365	0.602534635875652	1.71951255285113	0.583863802839919	0.39358121970129	NA	NA	0.313705386305915	0.0692208899789992	76.6512774752853
a4872	loss_cnaOV84	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	3.148381363203	2.55204040452248	0.596340958680517	1.59196962209302	1.22631570016991	0.451265495475497	0.37459317715905	0.486286654079283	0.393903359463599	NA	NA	0.940426817056127	0.476545416977146	76.6512774752853
a4873	gain_cnaOV51_(MYC)	211	TL-2-105	CRAF	8	24	2.32630161961136	1.63315443905142	4.29438535713236	4.4474050375263	-0.153019680393937	0.572585310026363	0.650948096349802	0.241534632656546	0.267243461741783	0.235072014576887	0.393923579157602	NA	NA	0.268136782023845	0.537946221918771	76.6512774752853
a4874	loss_cnaOV40	164	JQ12	HDAC	4	15	1.63315443905142	NA	0.853667596496036	2.04461984705734	-1.19095225056131	2.92504169604267	1.99038158511375	0.545164223602845	0.407157358533577	0.598353732504636	0.394020497135296	NA	NA	0.656618299032288	0.48756906722905	76.6512774752853
a4875	loss_cnaOV55	310	YM201636	FYV1	7	25	1.63315443905142	NA	2.08207468724213	2.43387229918896	-0.351797611946834	0.853287588790858	0.863949801392765	0.408199371581617	0.412284927811202	0.407196820208424	0.394060210441459	NA	NA	0.648478364580659	0.359565348375403	76.6512774752853
a4876	loss_cnaOV52, loss_cnaOV53	1114	Cetuximab	EGFR	9	23	4.18661983833127	NA	6.07054914724506	5.7252766900359	0.345272457209163	1.51423478933304	1.19408407235713	0.268221389773931	0.228017781417663	0.289152552322041	0.394094051527613	NA	NA	0.568504961449591	0.550915276392247	76.6512774752853
a4877	TP53_mut	275	I-BET	BRD2, BRD3, BRD4	21	10	2.99573227355399	NA	3.79135930842661	4.18970379738814	-0.398344488961528	1.31084408919225	0.974973243362905	0.327431812930064	0.303883957097439	0.408569662473554	0.394166513036617	NA	NA	0.696856465749463	0.353255222949849	76.6512774752853
a4878	loss_cnaOV52, loss_cnaOV53	253	XMD14-99	EPHB3, CAMK1	8	24	2.32630161961136	NA	5.09283462862882	4.78247363562926	0.310360992999559	0.528426955097553	0.632636565833881	0.508858880038513	0.587329980058007	0.49058339299511	0.394257105728541	NA	NA	0.0483041720680436	0.192880437090111	76.6512774752853
a4879	gain_cnaOV94	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	2.76770119065445	2.09617638009379	0.671524810560663	1.0678991005954	1.32803843723217	0.517204243413785	0.628827957797007	0.50565163758379	0.394399991085643	NA	NA	0.682135269284259	0.40411381303737	76.6512774752853
a4880	loss_cnaOV81_(RB1)	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.67683078558976	2.31655072488312	0.360280060706639	0.831181965712944	0.873312022613205	0.41450049082172	0.433455098364183	0.412544487397043	0.394424298316877	NA	NA	0.605636734482397	0.465479992213436	76.6512774752853
a4881	loss_cnaOV58	1069	EHT 1864	Rac GTPases	5	28	2.30258509299405	NA	4.65866930518531	4.15265574147196	0.506013563713351	1.20759376564965	0.927707727971875	0.522537053711219	0.419026313406918	0.545445023746414	0.394444064213737	NA	NA	0.206854792488408	0.414607401526697	76.6512774752853
a4882	gain_cnaOV94	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.85262947931311	2.00550961135082	0.847119867962289	2.03194706243336	1.44866748742887	0.554077871848998	0.416900559873749	0.584757976080332	0.394452510208015	NA	NA	0.947095103744921	0.550998592421876	76.6512774752853
a4883	KRAS_mut	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	6.23686347173758	5.70633047575472	0.530532995982863	0.770041903294438	1.37516323526037	0.415360547481147	0.68896639742994	0.385796378480417	0.394473692089428	NA	NA	0.568512820495359	0.201853837594564	76.6512774752853
a4884	gain_cnaOV95_(MECOM)	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	7.29962875876013	6.4826464115905	0.816982347169625	1.65808207944669	1.43087542455726	0.549246090794002	0.492727324718603	0.570966789385189	0.394821737252556	NA	NA	0.331462467418715	0.363706972842081	76.6748265137343
a4885	RB1_mut	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.31400178762942	-4.13967698028325	0.82567519265383	1.57055949273369	1.51255828877363	0.544414535856195	0.525720417770788	0.545879916682933	0.394838805004438	NA	NA	0.863196616902397	0.462782444639416	76.6748265137343
a4886	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.99737529252873	1.5748637756564	0.422511516872333	1.30595184271492	0.608253520084467	0.623631908680153	0.323527639421973	0.694630615230405	0.394900304017443	NA	NA	0.206250828881767	0.633013334912859	76.6748265137343
a4887	loss_cnaOV85	177	GSK-650394	SGK3	6	13	2.77258872223978	NA	4.36465971048392	3.76348504681908	0.601174663664833	1.69133447890013	1.47988893304481	0.389088281602283	0.355443982940486	0.406229582667357	0.394918123212277	NA	NA	0.740154916938999	0.473945386812161	76.6748265137343
a4888	loss_cnaOV33_(ZFHX3)	326	GSK690693	AKT	4	28	2.32630161961136	NA	4.87776179319215	4.04824105665074	0.829520736541409	0.783792089067289	1.4978232586501	0.575091723972516	1.0583428285536	0.553817502666509	0.395053901260486	NA	NA	0.0915903773685593	0.131522507098034	76.6748885413983
a4889	loss_cnaOV81_(RB1)	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	4.74288386811866	3.77809602266575	0.964787845452909	0.630501629433848	1.77927103206391	0.568562727108664	1.53019088359729	0.542237707503042	0.395080062678167	NA	NA	0.144730043133867	0.059858211115176	76.6748885413983
a4890	SMAD4_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.78318729480191	2.32696872903995	0.456218565761961	1.09166409379704	0.96763622697346	0.464089395605697	0.417911121520115	0.471477351761525	0.395364986991804	NA	NA	0.404758616021645	0.553882884404717	76.7144937851323
a4891	loss_cnaOV33_(ZFHX3)	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.20620770197467	4.43814189106398	-0.231934189089303	0.456103072078642	0.648901330063404	0.366826252156872	0.508512665859248	0.357425972707809	0.395472425964628	NA	NA	0.268175785489293	0.411912776523033	76.7174475371201
a4892	gain_cnaOV94	1033	Vismodegib	SMO	7	24	2.30258509299405	NA	5.24268705195649	4.81418473647915	0.428502315477338	0.644222091565791	0.892840885972305	0.505662163190411	0.665146881932994	0.479931331785616	0.395541919498453	NA	NA	0.151639298960308	0.181486072933553	76.7174475371201
a4893	loss_cnaOV34	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	-0.110666599553832	0.845559376194686	-0.956225975748518	2.62548307483192	2.24806969904118	0.4153947332569	0.36420953725239	0.425354238863837	0.395658184390758	NA	NA	0.945496591748293	0.478326327132787	76.7226721908017
a4894	PTEN_mut	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.47040216601934	4.25803039391521	0.212371772104134	0.353877991901719	0.927781081354014	0.235715422005568	0.600127097372914	0.228902891395669	0.39573057762126	NA	NA	0.518935241273797	0.458881728428586	76.7226721908017
a4895	loss_cnaOV54	262	VX-11e	ERK	10	22	1.63315443905142	NA	2.54890502920321	3.0003560227951	-0.451450993591885	1.37267954607124	0.973927899954859	0.407183874264648	0.328883019262572	0.463536359942876	0.395839868112709	NA	NA	0.387824586647466	0.364875924550942	76.7281829866653
a4896	gain_cnaOV48_(SOX17)	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	1.91521486022739	2.40776202960014	-0.492547169372754	0.563575423734559	0.882858198476115	0.569256850133929	0.873968502935893	0.557900657458843	0.396078192704981	NA	NA	0.605668574824377	0.265818420248575	76.7586979310077
a4897	gain_cnaOV4_(KRAS)	260	NG-25	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	2.72617808279305	3.10724961687936	-0.381071534086305	1.04829348548346	1.08613884416614	0.353686583083371	0.363516075758651	0.350849742768261	0.39625861748836	NA	NA	0.43167437600214	0.394337572976218	76.7594607854772
a4898	loss_cnaOV16, loss_cnaOV17	228	KIN001-102	AKT1	6	26	2.32630161961136	NA	3.29591392123873	2.67184783591216	0.62406608532657	0.554412645212116	1.3055274627524	0.514447457092279	1.12563465266526	0.478018351303673	0.396289827906446	NA	NA	0.0928184803401312	0.0831191469894304	76.7594607854772
a4899	gain_cnaOV49	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.83359244934197	3.24749451048033	0.586097938861641	1.52497119092558	1.06547917947102	0.531806694811992	0.38433377781118	0.550079203943357	0.39632482644996	NA	NA	0.950617429045406	0.577128027822135	76.7594607854772
a4900	gain_cnaOV51_(MYC)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	-1.38629436111989	0.693147180559945	-1.83860776531764	-2.21476563651928	0.376157871201642	0.91848446201135	1.38343895179465	0.290885982838054	0.409541899465463	0.271900592876668	0.396518042747328	NA	NA	0.605375907078849	0.389509477682608	76.77100543569
a4901	loss_cnaOV16, loss_cnaOV17	1017	Olaparib	PARP1, PARP2	6	25	1.6094379124341	NA	4.47479367332496	3.8483988950878	0.626394778237158	1.22275778615018	1.13320189385559	0.545098463450565	0.512280343116314	0.552765382438533	0.396567563327883	NA	NA	0.0809765686226284	0.289732589393416	76.77100543569
a4902	ARID1A_mut	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	2.77201327252288	3.51510143754514	-0.743088165022264	1.23507831186328	0.811830050781226	0.799937927676087	0.601652670834464	0.915324782948338	0.396627167729648	NA	NA	0.185056464906022	0.26300391471851	76.77100543569
a4903	gain_cnaOV4_(KRAS)	1023	GW 441756	NTRK1	5	26	0.693147180559945	NA	1.85549790403506	2.38365531644956	-0.528157412414499	1.62349207591579	1.1809368811185	0.422080429423033	0.325321829560869	0.447235936872651	0.396938235582548	NA	NA	0.84352137444136	0.520079091304468	76.800069072223
a4904	loss_cnaOV84	229	LY317615	PRKCB (PKCbeta)	6	26	2.99573227355399	2.32630161961136	2.34209164196934	2.84292502280819	-0.500833380838855	0.886183582680122	1.79912723392323	0.297805622624868	0.56515759333316	0.278375743191171	0.396939204986217	NA	NA	0.318338847995528	0.336303073859401	76.800069072223
a4905	gain_cnaOV95_(MECOM)	1016	Temsirolimus	MTOR	8	23	-1.6094379124341	NA	-1.58988148445022	-2.18221932795749	0.592337843507271	1.38577203385151	1.59986148221243	0.381933421331763	0.427442486237056	0.370243205485597	0.397063196212723	NA	NA	0.0367063658485413	0.334550674869227	76.8080705118683
a4906	loss_cnaOV16, loss_cnaOV17	1194	SB-505124	TGFR1 (ALK5)	6	26	2.30258509299405	NA	4.87904766588338	4.52137323769402	0.357674428189357	0.903591651717391	0.948631677691095	0.379989427810744	0.395836357617461	0.377042467166933	0.397224620492625	NA	NA	0.942786631737431	0.41258133215128	76.8080705118683
a4907	loss_cnaOV70	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.50126318248471	5.74977206293851	-0.248508880453801	0.632292658008291	0.6027662781436	0.410908205060406	0.393028255676096	0.412280662447074	0.397324210791126	NA	NA	0.189667794400167	0.572147939274221	76.8080705118683
a4908	PTEN_mut	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.72210679625576	2.23056011976666	0.491546676489105	0.365278843840367	0.934011500871867	0.550967649139638	1.34567518699199	0.526274757891379	0.397573674386508	NA	NA	0.592032927931033	0.0826936800206501	76.8080705118683
a4909	gain_cnaOV72_(ASXL1)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	2.8588953744854	2.27636533674022	0.582530037745184	0.944208794633901	0.971298101403683	0.602675799521196	0.616950446824687	0.599743824170287	0.397622674454148	NA	NA	0.404860430686293	0.327011456271742	76.8080705118683
a4910	loss_cnaOV20	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.51397419497038	2.83976504764061	-0.325790852670231	1.10927728555573	1.25078075204167	0.264257797715995	0.293696496730315	0.260469992153651	0.397654705235114	NA	NA	0.0928411113017511	0.576005071024848	76.8080705118683
a4911	loss_cnaOV36	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	1.89824925700783	2.49565922454404	-0.597409967536211	3.5177202190719	1.18218452694033	0.409401363038194	0.169828732909813	0.505344093009233	0.397678366144902	NA	NA	0.237277413259874	0.796931018003474	76.8080705118683
a4912	loss_cnaOV59	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	4.56334024380079	3.78447002263286	0.778870221167924	1.28398020037039	1.61204995865043	0.492559518046898	0.606606099489109	0.48315513857894	0.397689483468092	NA	NA	0.713850234471875	0.329266243471164	76.8080705118683
a4913	NF1_mut	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	-0.335091401198619	0.459642086215771	-0.794733487414391	0.506512669475264	1.75232025255655	0.476691015397746	1.56902982947636	0.45353210194022	0.397709113454079	NA	NA	0.836177077472157	0.0767985213500162	76.8080705118683
a4914	loss_cnaOV21, loss_cnaOV22	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.61816757737029	4.89664704642974	0.72152053094055	0.561630122820161	1.26267151042725	0.587344303951412	1.28468987261139	0.571423782814587	0.397812836799467	NA	NA	0.369668148179591	0.136997875452967	76.8117011668824
a4915	loss_cnaOV1	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.68429449292657	4.09766476995111	0.586629722975451	0.678741121494206	1.04312844367203	0.573137060608153	0.864290823700239	0.562375349396468	0.397967501031394	NA	NA	0.527236676133425	0.269635569715715	76.8117011668824
a4916	loss_cnaOV55	1175	AG-014699	PARP1, PARP2	8	25	1.6094379124341	NA	4.25598022570251	3.78761479861166	0.468365427090853	0.878877685347244	1.11153227857206	0.440418375771456	0.532913094619989	0.421369164098897	0.39797077539654	NA	NA	0.313569952284686	0.239312278318452	76.8117011668824
a4917	gain_cnaOV4_(KRAS)	292	Masitinib	KIT	8	24	2.99573227355399	NA	4.28037966880197	3.92456733757105	0.355812331230922	1.37642708501124	0.923379596423248	0.339911814994907	0.258504308078198	0.38533700832158	0.398053079265715	NA	NA	0.102649390298151	0.512168035336823	76.8119616142051
a4918	loss_cnaOV20	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.32186291188074	8.81294762095587	-0.491084709075135	1.23196644671477	1.23416538274081	0.397981644074257	0.398618574706063	0.397908348380785	0.398135931162829	NA	NA	0.52730249608566	0.498791963050574	76.8123276865904
a4919	loss_cnaOV82	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.6312700177036	3.31525317967426	-0.683983161970657	0.560182858283035	1.10404268227143	0.635454256381604	1.22099980721843	0.619526013761936	0.398258760423496	NA	NA	0.0608686092500047	0.150717809176049	76.8204048711524
a4920	loss_cnaOV34	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.72235372568812	2.21141701296313	0.510936712724992	1.43935548702469	1.40494423209485	0.362433152808119	0.354976041242705	0.36367045826663	0.398489492285502	NA	NA	0.527310685937402	0.495093111181601	76.8242188746295
a4921	loss_cnaOV81_(RB1)	326	GSK690693	AKT	4	28	2.32630161961136	NA	4.87367539694663	4.04882482754296	0.824850569403672	0.914819217794233	1.48988144024736	0.571730145818909	0.901654177524288	0.553635039085207	0.398544092386921	NA	NA	0.0916478702446588	0.178866440439686	76.8242188746295
a4922	loss_cnaOV102	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	9.55303543611269	8.67227358535892	0.880761850753773	1.1347438735487	1.73700255767447	0.517388561694861	0.776176784281157	0.507058465091123	0.398778679575719	NA	NA	0.921295634342164	0.312716614499306	76.8242188746295
a4923	loss_cnaOV55	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	5.02977632959873	4.67651089535377	0.353265434244959	1.1330086292455	1.25281362312153	0.287444880549257	0.311794125063468	0.28197764434007	0.398872324510095	NA	NA	0.421952948606681	0.493944372599902	76.8242188746295
a4924	loss_cnaOV82	1028	VX-702	p38	3	28	0.693147180559945	NA	3.80827922499729	3.27540029270274	0.532878932294551	0.99553456846098	0.913334834443384	0.579695238977993	0.535269139994145	0.583443127535264	0.39892118705753	NA	NA	0.515436324324062	0.455202102374352	76.8242188746295
a4925	loss_cnaOV34	1262	UNC1215	LMBL3	5	28	0	NA	2.6724845647945	2.79968558663685	-0.127201021842349	0.780526632071262	0.439166819794903	0.256154689438811	0.162968202000743	0.289641694474445	0.398928158468271	NA	NA	0.107699881666601	0.739072861979735	76.8242188746295
a4926	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.28203720376843	2.55318655338605	-0.271149349617627	0.679904980501383	0.617762979335422	0.432865969308441	0.398804770363166	0.438921331785411	0.398989172605038	NA	NA	0.857241684323478	0.442052478771363	76.8242188746295
a4927	KRAS_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.8563112477098	1.67406378822967	1.18224745948013	2.66675522971939	1.43021611473378	0.72741283435731	0.443328073872208	0.826621548520445	0.399075841401001	NA	NA	0.340561659989229	0.525647228320476	76.8242188746295
a4928	loss_cnaOV20	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.3394030089605	4.847467814939	0.491935194021496	0.885421504777554	0.846371974248904	0.5784106327155	0.555594359711295	0.581228123081526	0.399098740202721	NA	NA	0.151716716879344	0.357890536198865	76.8242188746295
a4929	gain_cnaOV94	1025	SB 216763	GSK3A, GSK3B	5	18	2.30258509299405	NA	5.28792119429458	4.86885465537848	0.419066538916103	0.570411760002142	0.862685970781097	0.514107055287946	0.734673736240167	0.485769507224824	0.39911070097757	NA	NA	0.450077889397217	0.228550598254999	76.8242188746295
a4930	PIK3CA_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	6	26	1.63315443905142	NA	3.42841272996042	2.73346454387266	0.694948186087762	0.736676373532728	0.764507107376753	0.914478384008011	0.943356148039798	0.909014683293569	0.39916917445899	NA	NA	0.0188166843428334	0.0738174705135808	76.8242188746295
a4931	loss_cnaOV44	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.89372782731486	4.33482493000916	0.558902897305702	0.449624786361614	1.00643433087789	0.570766808492753	1.24304289767557	0.555329722127209	0.399382536748313	NA	NA	0.50891352091643	0.147155649908655	76.8496944714176
a4932	loss_cnaOV54	1069	EHT 1864	Rac GTPases	11	22	2.30258509299405	NA	4.5146031239068	4.08668513291666	0.427917990990132	0.518554555047724	1.11536676648101	0.443854301024494	0.82521305969581	0.383656752065705	0.399510127925132	NA	NA	0.206970144076738	0.142820083112561	76.8586588975192
a4933	loss_cnaOV39	222	BX-912	PDPK1 (PDK1)	9	23	2.32630161961136	NA	3.20607721182521	3.48968066280601	-0.283603450980806	1.03784161076032	1.285506241352	0.231632034830933	0.273262748419808	0.220616160278252	0.399874967417994	NA	NA	0.323853176051407	0.525095284000818	76.90157231197
a4934	MLL2_mut	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	-0.317424354009507	0.429365849466424	-0.746790203475931	0.441958124264161	1.73102984262417	0.446031144316028	1.68973068369158	0.431413823775462	0.39989528900068	NA	NA	0.836196438889187	0.0977917730622701	76.90157231197
a4935	SMARCA4_mut	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	1.91479785743011	2.33461274451544	-0.419814887085336	0.956627093769996	0.894759024948625	0.466895475775205	0.438849045588785	0.469193241285765	0.400231168295919	NA	NA	0.592086647127068	0.53190406774612	76.9485640466272
a4936	loss_cnaOV43_(NF1)	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.28184077880948	-2.83453218314098	0.552691404331496	1.38299088938133	1.20244367667685	0.45115221204104	0.399634884492072	0.459640160326633	0.40034299731738	NA	NA	0.373662457084181	0.569709297438948	76.9485640466272
a4937	gain_cnaOV51_(MYC)	256	JW-7-24-1	LCK	8	24	2.32630161961136	NA	1.6116951255001	2.04856056647629	-0.436865440976195	1.24285967421836	1.36668533629751	0.326306955176572	0.351500213610954	0.319653273049455	0.400407533114817	NA	NA	0.838085265128486	0.416304517493425	76.9485640466272
a4938	loss_cnaOV57_(ZNRF3)	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	3.64695731264107	2.43584622447835	1.21111108816272	2.23900713249818	2.32550285204181	0.522706873615439	0.540914350197456	0.52079535705551	0.400599496533883	NA	NA	0.383133915276408	0.371094699791813	76.9485640466272
a4939	loss_cnaOV38	1375	Temozolomide	DNA akylating agent	8	25	3.40119738166216	NA	6.13450563992824	5.88729181500888	0.24721382491936	0.979916646862197	0.593700578451177	0.35326511892594	0.252280462538285	0.416394785338228	0.400657090746497	NA	NA	0.908165750102052	0.517191171348782	76.9485640466272
a4940	loss_cnaOV102	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	2.20800960622348	1.35017389483486	0.857835711388622	1.24578253582459	1.81997216556756	0.480228277957288	0.688591858306005	0.471345511551329	0.400706487887287	NA	NA	0.612427291272343	0.360581668088517	76.9485640466272
a4941	loss_cnaOV55	157	JNK-9L	JNK	4	15	1.63315443905142	NA	-0.505300078170102	0.0948472640152736	-0.600147342185376	0.843487563291446	1.01565254901573	0.60777239350447	0.711507043261538	0.590898277926818	0.400730066632413	NA	NA	0.185839164867292	0.27550440248315	76.9485640466272
a4942	loss_cnaOV43_(NF1)	1026	17-AAG	HSP90	5	28	0	NA	0.542437987841905	-0.722487541527898	1.2649255293698	0.973258115546908	2.40094923112266	0.557773784355359	1.2996814608209	0.526843930297659	0.400792117016608	NA	NA	0.0598674012679579	0.0627810641787122	76.9485640466272
a4943	loss_cnaOV85	305	TPCA-1	IKK	7	25	2.99573227355399	NA	2.97668370570037	3.42277817703916	-0.446094471338795	1.00249088822775	1.27574970241367	0.363867600083524	0.444986060798438	0.349672408698039	0.400869536231445	NA	NA	0.99357288736113	0.347980674756255	76.9485640466272
a4944	PTEN_mut	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	2.91792985663354	2.55302530917439	0.364904547459149	2.62506611872169	2.33026882762006	0.155207712641429	0.139007754835846	0.156593326544145	0.401132885017439	NA	NA	0.383147077134522	0.835632710489534	76.9835406797315
a4945	gain_cnaOV51_(MYC)	1026	17-AAG	HSP90	8	25	0	NA	0.342755587807312	-0.810380237041205	1.15313582484852	2.37510102149083	2.22367327029745	0.510518516500164	0.485510222266126	0.518572508043983	0.401270549454054	NA	NA	0.0598732510294434	0.24985116311146	76.9903221266835
a4946	loss_cnaOV44	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.8425354949958	1.10040772098829	0.742127774007513	1.73112532997024	1.47052789022859	0.49850129404091	0.428696733367233	0.504667595180499	0.401388298794021	NA	NA	0.812010122163619	0.539189704717814	76.9903221266835
a4947	gain_cnaOV51_(MYC)	1043	JNK Inhibitor VIII	JNK	8	25	2.30258509299405	NA	4.25264664278787	4.50264080398389	-0.249994161196014	1.12932585554631	0.974889810565669	0.247072540641572	0.221365835173481	0.256433248646796	0.401411647958916	NA	NA	0.37219428712836	0.585438745402533	76.9903221266835
a4948	loss_cnaOV59	304	SB52334	ALK5	4	28	2.99573227355399	NA	4.71701606143668	4.31658682135838	0.400429240078298	1.21715903824483	1.04382459864982	0.37689892224609	0.328986786028986	0.383617363105113	0.401528119208354	NA	NA	0.348970792475539	0.568278770568949	76.990625254023
a4949	PIK3R1_mut	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	3.69909549934738	4.95972498792362	-1.26062948857624	0.995030197201552	1.57166564285496	0.831956482366563	1.266925860262	0.80209775807422	0.401637543027836	NA	NA	0.117805943139823	0.141134460358389	76.990625254023
a4950	loss_cnaOV34	1033	Vismodegib	SMO	5	26	2.30258509299405	NA	4.72083244707495	4.94750310783924	-0.226670660764289	1.31409481931882	0.766737275431423	0.262616420732166	0.172491860885492	0.295630156544492	0.401656656679071	NA	NA	0.1517717879904	0.725466893822431	76.990625254023
a4951	loss_cnaOV84	268	YM155	BIRC5 (Survivin)	6	24	1.63315443905142	NA	-4.89166987680168	-3.96602957331064	-0.92564030349104	1.00800270435983	2.5339264262345	0.396295169867135	0.918291488194868	0.365298808168859	0.402130563270067	NA	NA	0.927581198790546	0.175603196311754	77.0243286356164
a4952	loss_cnaOV44	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	3.18149535729144	3.96034162551486	-0.778846268223419	0.714024624930312	1.63256492013813	0.490956650049236	1.09078348425229	0.477069094537153	0.402132375635273	NA	NA	0.713916501827001	0.193709976406995	77.0243286356164
a4953	loss_cnaOV85	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	2.97079489766978	2.29093203996449	0.679862857705288	1.31342327006376	1.47157090485044	0.471691244476608	0.517626627455965	0.461998029088775	0.402294544394769	NA	NA	0.237388846697854	0.264479387575094	77.0243286356164
a4954	loss_cnaOV83	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	4.91132920835642	4.52864237531714	0.382686833039275	1.00124825338292	0.931825742996223	0.406517747441405	0.382209738440282	0.410684976150981	0.4024109524041	NA	NA	0.942802257948561	0.461188736963629	77.0243286356164
a4955	gain_cnaOV50	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.75374485149021	2.47611584122517	0.277629010265041	0.414405732219371	0.646835420029222	0.442451606008523	0.669944908286343	0.429211205305514	0.402426527907081	NA	NA	0.857267198819243	0.297169707290524	77.0243286356164
a4956	loss_cnaOV39	330	XMD13-2	RIPK	9	23	2.32630161961136	NA	3.83704717884393	4.18066459613608	-0.343617417292156	1.19639087445907	1.08838060016669	0.307294055058015	0.287211666878953	0.315714390020852	0.402484443894789	NA	NA	0.818576111653885	0.466779680738119	77.0243286356164
a4957	loss_cnaOV41	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.63246064716796	2.93336210277724	0.699098544390721	1.25922523969267	1.16823014032293	0.593477659818609	0.555181489660534	0.598425361801976	0.402508635241585	NA	NA	0.086702467508656	0.357501217469006	77.0243286356164
a4958	loss_cnaOV42	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.63246064716796	2.93336210277724	0.699098544390721	1.25922523969267	1.16823014032293	0.593477659818609	0.555181489660534	0.598425361801976	0.402508635241585	NA	NA	0.086702467508656	0.357501217469006	77.0243286356164
a4959	gain_cnaOV95_(MECOM)	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	5.06862072203032	4.6506987639049	0.41792195812542	1.33034227950002	1.64840783499571	0.264617733197979	0.314146189717797	0.253530679273014	0.402946691541841	NA	NA	0.117848713178901	0.586530115726346	77.0243286356164
a4960	RB1_mut	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.21112229342654	4.54772369979344	-0.336601406366894	0.383313999911818	0.607870232236815	0.56520378073895	0.878134914050438	0.553738920769787	0.402970271537162	NA	NA	0.612962132301042	0.264159702638083	77.0243286356164
a4961	loss_cnaOV43_(NF1)	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-5.09624437157795	-4.00575967438283	-1.09048469719511	0.868770403041302	2.45344126203227	0.466884998440143	1.25520470469258	0.444471491561949	0.402987879034656	NA	NA	0.927584676742189	0.117117715737785	77.0243286356164
a4962	TP53_mut	176	IPA-3	PAK1, PAK2, PAK3	12	7	3.46573590279973	NA	5.02374385493609	4.309708577941	0.714035276995095	1.75958512394595	1.05950896596723	0.460947935498668	0.405797518561556	0.673930377118845	0.403124626391847	NA	NA	0.117854511340912	0.285072277515708	77.0243286356164
a4963	gain_cnaOV51_(MYC)	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.315125811003	2.83983159007875	0.475294220924255	0.393783362645658	0.894671673718094	0.564770339831911	1.20699416483968	0.531249881813088	0.403227704440397	NA	NA	0.325831181043199	0.123093035034903	77.0243286356164
a4964	loss_cnaOV43_(NF1)	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.477086815705013	-1.47301243270119	0.995925616996176	1.93967929868637	1.83578668502386	0.538345106299527	0.513448598266042	0.542506177390229	0.403240733423181	NA	NA	0.0725203577633039	0.332754180522954	77.0243286356164
a4965	loss_cnaOV20	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.84711014153764	3.30054930047436	-0.453439158936723	1.1325227129881	1.24368558922119	0.368816219024436	0.400379748447028	0.36459307952637	0.403247551793383	NA	NA	0.5987798413722	0.449457536522298	77.0243286356164
a4966	NF1_mut	326	GSK690693	AKT	4	28	2.32630161961136	NA	4.54019350086598	4.09646509841162	0.443728402454353	0.186810364180962	1.5399776551111	0.303477709722592	2.37528792580542	0.28813950707768	0.40337937016309	NA	NA	0.0917263585297763	0.156954009905314	77.0243286356164
a4967	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	3.59560314384032	3.21549458041874	0.380108563421588	1.50336355815338	1.05417539808436	0.3487566952312	0.252838750387487	0.360574306811103	0.403468548525846	NA	NA	0.060935152966993	0.707324928263567	77.0243286356164
a4968	loss_cnaOV40	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	3.21129314487411	2.57501999332222	0.636273151551885	1.82217632700013	1.18798379723033	0.481226003466576	0.349183085151473	0.535590765661364	0.403585335975088	NA	NA	0.940482825879601	0.546909515106101	77.0243286356164
a4969	loss_cnaOV59	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.488193791280302	-0.00267821374209429	-0.485515577538208	1.42467420197892	0.891332129812302	0.506737370275069	0.340790601011664	0.544707815750397	0.403599364573375	NA	NA	0.546597169008467	0.550039129995238	77.0243286356164
a4970	gain_cnaOV4_(KRAS)	228	KIN001-102	AKT1	8	24	2.32630161961136	NA	3.09661121133835	2.68627656543507	0.410334645903288	1.30790424045246	1.19893039731915	0.334905582759681	0.313734471692924	0.342250598384035	0.403660163700122	NA	NA	0.092939401750801	0.44912705017737	77.0243286356164
a4971	loss_cnaOV84	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	2.63855852098589	1.9609464010445	0.677612119941391	0.652768516684703	1.71316244698165	0.442532704635091	1.03805882578845	0.395532905320946	0.403795526987065	NA	NA	0.947143057102664	0.229256233173696	77.0243286356164
a4972	loss_cnaOV70	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.46609163437646	1.60266167581321	0.863429958563252	0.759665019630672	1.51176239882561	0.585927037526872	1.13659301962203	0.571141311117404	0.403884585974433	NA	NA	0.323639334808864	0.173959042807489	77.0243286356164
a4973	loss_cnaOV83	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.64901224310041	3.73209120194987	0.916921041150543	1.48992728383235	1.47489781388747	0.620776823078092	0.615413282983894	0.621684453334272	0.403953938186144	NA	NA	0.0674510842879267	0.3206540139903	77.0243286356164
a4974	loss_cnaOV35	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	2.16112450418131	1.41437265353019	0.746751850651119	2.14232999403463	1.87675332325359	0.390092660160492	0.348569946147638	0.397895579242418	0.403965194758829	NA	NA	0.78135333790573	0.497310348334216	77.0243286356164
a4975	KRAS_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	7	26	0.693147180559945	NA	1.40457888104814	1.82749872475212	-0.422919843703977	0.908790532347593	1.84618524570295	0.247981311246398	0.465365591575309	0.22907768583263	0.403980401739983	NA	NA	0.226693325075959	0.406495067500247	77.0243286356164
a4976	TP53_mut	305	TPCA-1	IKK	22	10	2.99573227355399	NA	3.19966275176197	3.60136598271183	-0.401703230949857	1.31958528248797	0.971957163104188	0.327735533581772	0.304416270991201	0.413293143153467	0.404239006271207	NA	NA	0.993574018620586	0.344885933330261	77.0243286356164
a4977	gain_cnaOV4_(KRAS)	231	FMK	RSK	6	14	2.99573227355399	2.32630161961136	5.43744001358789	5.15946200163984	0.277978011948058	0.630408896676903	0.778700800946281	0.375395616702629	0.4409487451928	0.356976661138986	0.404316823091637	NA	NA	0.122888519525904	0.417754189768623	77.0243286356164
a4978	loss_cnaOV56	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.08074886251653	2.48267417042895	0.598074692087581	0.770543135497815	1.04394297028399	0.581502025451447	0.776172889660734	0.572899774328558	0.404751904166261	NA	NA	0.392499331097502	0.31025639591845	77.0243286356164
a4979	PIK3R1_mut	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	4.08047957768397	3.86837423830885	0.212105339375118	1.74255630293116	1.72524440930782	0.122771540259615	0.121720795487833	0.122942197772555	0.404755950996714	NA	NA	0.144934621513382	0.81172564192597	77.0243286356164
a4980	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.84855201899135	3.30028228613108	-0.451730267139737	1.13477392567417	1.24347077870556	0.367399813440067	0.398079526608229	0.363281771373817	0.404858188086396	NA	NA	0.598810285440268	0.451813029131609	77.0243286356164
a4981	ARID1A_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	1.77366734361716	1.89182983119417	-0.118162487577003	2.2553778678296	1.46861095437169	0.0700400151169823	0.0523914370458524	0.0804586723429122	0.40489934568503	NA	NA	0.340824459368181	0.917102268679173	77.0243286356164
a4982	loss_cnaOV34	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.33538254802773	3.74553873288977	-0.410156184862035	0.962137142896665	1.06339966301921	0.390453085213686	0.426297007542184	0.385702759861253	0.404983662815109	NA	NA	0.830012394889634	0.422569135903696	77.0243286356164
a4983	loss_cnaOV87, loss_cnaOV88	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.412162338785998	-1.29218741090266	0.880025072116658	1.09523575517487	1.32866885339917	0.672682261664643	0.803502869549897	0.662335893451	0.4050735157721	NA	NA	0.0475424849936082	0.29783126372949	77.0243286356164
a4984	loss_cnaOV44	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.47339174848867	1.47134717365807	1.0020445748306	0.775497201340174	1.65001269745413	0.623708868490889	1.29213177442667	0.60729506892686	0.405174019531366	NA	NA	0.0771842299273906	0.134328761563989	77.0243286356164
a4985	loss_cnaOV20	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	5.45898671886607	4.91782336903889	0.541163349827183	1.65105694528799	1.05036776201176	0.459069173904544	0.327767828584973	0.515213213313683	0.405190222257395	NA	NA	0.798664446436383	0.569985505616735	77.0243286356164
a4986	loss_cnaOV58	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.81296689598589	3.42265043961155	0.39031645637434	1.24315957124409	0.838493824639585	0.433213142288561	0.313971323877377	0.465497115070718	0.405200268849813	NA	NA	0.793083893301274	0.531525930952785	77.0243286356164
a4987	loss_cnaOV33_(ZFHX3)	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.66888888124555	2.31768528264658	0.351203598598973	0.704836718904532	0.886044123949156	0.403856744403372	0.498276535797992	0.396372583606374	0.405373866733237	NA	NA	0.605843982150901	0.413803198829978	77.0243286356164
a4988	ARID1A_mut	228	KIN001-102	AKT1	8	24	2.32630161961136	NA	2.14405286650628	3.00379601371242	-0.859743147206141	0.790293549387064	1.27242713904097	0.730007774422932	1.08787822939076	0.675671809274778	0.405376991023687	NA	NA	0.0929671210021732	0.0357027987556116	77.0243286356164
a4989	gain_cnaOV50	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-2.34524007146853	-1.98256059750926	-0.362679473959273	1.18648847505515	1.6071214766248	0.231175899734806	0.305674670748417	0.225670230430219	0.405441061060638	NA	NA	0.0367856936711528	0.61189912886074	77.0243286356164
a4990	loss_cnaOV56	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	3.85127919699661	4.33019605046077	-0.47891685346416	0.29922308179	0.838563110118619	0.589119011863108	1.6005344594381	0.571116052787505	0.405572457757557	NA	NA	0.314017229623069	0.0838510720259023	77.0243286356164
a4991	gain_cnaOV96	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.69776294321193	4.16471225911357	0.533050684098361	0.822786978623412	0.984287002718129	0.549630820684759	0.647859893201273	0.541560218337061	0.405577053733085	NA	NA	0.20710554970002	0.297885913478579	77.0243286356164
a4992	gain_cnaOV49	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	4.85257810598111	5.08366939227946	-0.231091286298351	0.261463286827889	0.636658406550725	0.373472263385805	0.883838374029426	0.362975315994572	0.40558557806971	NA	NA	0.108609438093876	0.281342095633953	77.0243286356164
a4993	NF1_mut	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	5.26655316129316	4.89229889561441	0.374254265678752	0.500067557004546	0.842697351364813	0.458727681156839	0.748407411031764	0.444114681353416	0.405643198356817	NA	NA	0.94567500435992	0.25372266546269	77.0243286356164
a4994	loss_cnaOV70	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.10924563811423	4.35293783747996	-0.24369219936573	0.411313461087222	0.59867281784198	0.414673595102483	0.592473192395843	0.407054057079391	0.405790736644507	NA	NA	0.251250358782836	0.422567426985839	77.0243286356164
a4995	loss_cnaOV52, loss_cnaOV53	1262	UNC1215	LMBL3	9	24	0	NA	2.95007069347576	2.71679095868844	0.233279734787324	0.490655022105829	0.485924210476177	0.47886686194674	0.475445525424599	0.480074319735425	0.406006316682681	NA	NA	0.10782035678282	0.242365726233431	77.0243286356164
a4996	loss_cnaOV20	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.732087524726256	0.330458107619232	0.401629417107024	0.565428809212086	0.939880939413583	0.442161786992666	0.710309433413353	0.427319461715663	0.406130905758604	NA	NA	0.909114897042939	0.27770749693136	77.0243286356164
a4997	PTEN_mut	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	3.77066687324448	4.37794307984286	-0.607276206598388	0.987819291744684	0.75257159521136	0.77835578290047	0.614764473293307	0.806934795921755	0.406233858124425	NA	NA	0.222413059052289	0.311319023903302	77.0243286356164
a4998	loss_cnaOV54	1268	XAV 939	TNKS1 (tankyrase-1)	10	22	1.6094379124341	NA	2.99658014401071	2.79190017535585	0.20467996865486	0.872679807400144	1.15329244440838	0.190079137394975	0.23454188686299	0.177474472886067	0.406260959506096	NA	NA	0.304079576553571	0.585129500801293	77.0243286356164
a4999	loss_cnaOV35	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	-0.0923962691659262	0.842175981678407	-0.934572250844333	2.61880485744974	2.25074405805156	0.40576774555188	0.356869756135416	0.415228132004213	0.406434075306781	NA	NA	0.94552738653327	0.486924909541709	77.0243286356164
a5000	loss_cnaOV59	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.50526134501617	3.64320936615679	0.862051978859378	1.73546538556184	1.5244483107388	0.557555191942234	0.496726691313579	0.565484557781825	0.406443220946696	NA	NA	0.162912448369404	0.402887821152494	77.0243286356164
a5001	gain_cnaOV96	170	Shikonin	unknown	4	14	2.77258872223978	NA	0.247372016783708	-0.0851819060261921	0.3325539228099	0.418720057468495	0.852393930790044	0.421252697025394	0.794215411653457	0.390141119965121	0.406565825945498	NA	NA	0.579946333809697	0.305853155841089	77.0243286356164
a5002	loss_cnaOV70	326	GSK690693	AKT	3	29	2.32630161961136	NA	4.96224059885834	4.0681060331867	0.894134565671641	0.762102178473716	1.48191468518135	0.618724707199142	1.17324761813744	0.603364400537147	0.406590163442004	NA	NA	0.0917777449318644	0.163197538775814	77.0243286356164
a5003	loss_cnaOV82	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.97265943953058	4.38897383077695	0.583685608753639	1.35744831020712	0.973825879784015	0.581932126666573	0.429987355219867	0.59937368771006	0.406678967779083	NA	NA	0.372319037791276	0.536808607377815	77.0243286356164
a5004	loss_cnaOV58	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	4.84236243658151	4.21244918965262	0.629913246928888	1.41765103578169	1.28152813994609	0.484588306652022	0.444335898630762	0.491532903019507	0.406740042188547	NA	NA	0.368477279471406	0.394104672308395	77.0243286356164
a5005	gain_cnaOV49	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	3.90145530977113	4.22760785919916	-0.326152549428023	0.823049073471365	0.986994624878339	0.333857561196939	0.396273515080228	0.330450177951299	0.40682318885927	NA	NA	0.0469489026270838	0.573210076108731	77.0243286356164
a5006	loss_cnaOV34	1003	Camptothecin	TOP1	5	26	-2.30258509299405	NA	-4.10910943265004	-3.61079453542483	-0.498314897225211	2.57517568228212	1.55686109762095	0.28750150336805	0.19350714619346	0.320076658082529	0.40694714507003	NA	NA	0.242454199303611	0.694652891478358	77.0243286356164
a5007	RB1_mut	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	0.0737093665889275	0.920887263469095	-0.847177896880168	0.924536281799554	1.35669496802732	0.635519282810634	0.916327367089571	0.624442425781228	0.407067779529444	NA	NA	0.161067772884328	0.24719736756398	77.0243286356164
a5008	PIK3CA_mut	192	LFM-A13	BTK	5	14	2.77258872223978	NA	4.52767953086775	4.79558731055956	-0.267907779691813	0.438749365255107	0.749030581565839	0.388995841841202	0.610616905476413	0.35767268558215	0.407277360833675	NA	NA	0.956453633246246	0.357325803660807	77.0243286356164
a5009	loss_cnaOV34	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.45834406381917	2.99812665471795	0.460217409101221	1.28477838944146	0.840862283818287	0.505518273735198	0.358207619993745	0.547316032551028	0.407397101638444	NA	NA	0.23635162967638	0.47763601726617	77.0243286356164
a5010	gain_cnaOV49	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	3.6296036395147	2.65792377676845	0.97167986274625	0.755215951825835	1.71509319700495	0.582411996346804	1.2866251836936	0.566546392022944	0.407620939491503	NA	NA	0.318604547195741	0.136768574003053	77.0243286356164
a5011	loss_cnaOV43_(NF1)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.8442381379784	3.42141331055877	0.422824827419624	0.786885286380864	1.15537309584606	0.380295677361398	0.537339857203749	0.365963885553347	0.407744550873222	NA	NA	0.725253796074295	0.342731634635218	77.0243286356164
a5012	loss_cnaOV39	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	2.00760713913173	2.42212801785647	-0.414520878724742	1.32459756689741	1.20027843165413	0.33682801374261	0.31294099361489	0.345353934381277	0.407942952078002	NA	NA	0.384307073865791	0.559200418372582	77.0243286356164
a5013	loss_cnaOV57_(ZNRF3)	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.80279818214088	4.34023993242239	0.462558249718495	0.683174634983914	0.770268109045313	0.607254667824146	0.677071755934537	0.600515903860799	0.408084743631734	NA	NA	0.041957362327219	0.278734215342053	77.0243286356164
a5014	loss_cnaOV70	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.5648684457139	3.01815537713522	0.546713068578675	0.279237276564984	0.939926362662677	0.599555982458138	1.95787996253231	0.581655212893396	0.40808839339534	NA	NA	0.23636730484931	0.0474397085169072	77.0243286356164
a5015	loss_cnaOV41	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.71248714021288	2.21331443324683	0.499172706966053	1.42194502573307	1.40848578671341	0.353935372792464	0.351049230407983	0.354403794255412	0.408151062288862	NA	NA	0.527524567415753	0.500369094564795	77.0243286356164
a5016	PIK3R1_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	3.61889239118133	4.30409377371046	-0.685201382529124	0.606292074435603	0.989743467675149	0.723072810246968	1.13015065085087	0.692302000374524	0.40818393358445	NA	NA	0.0469632717696267	0.0700405713297882	77.0243286356164
a5017	loss_cnaOV33_(ZFHX3)	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.33090518311597	4.51298335082717	-0.182078167711195	0.73397482875956	0.672746716517175	0.268023485496288	0.248071405962126	0.270648913240064	0.408189807482107	NA	NA	0.0521181645663993	0.665522230296329	77.0243286356164
a5018	gain_cnaOV50	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.14413536713262	3.52836225243181	-0.384226885299189	1.08743179568929	0.88124460988887	0.425379091449023	0.353334238360798	0.436004806143033	0.408381949795085	NA	NA	0.793115834950588	0.539947165572943	77.0243286356164
a5019	PIK3R1_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.8423459419758	1.6766822830548	1.165663658921	2.41713650215747	1.49039612369384	0.716424912362297	0.482249826553265	0.782116673808831	0.40851276627278	NA	NA	0.340984767176345	0.494812738144633	77.0243286356164
a5020	TP53_mut	346	THZ-2-102-1	CDK7	22	10	0.916290731874155	2.99573227355399	-0.852494663658068	-1.51465003996202	0.662155376303952	2.20384313160181	1.23561153490428	0.33712132940593	0.300454858519209	0.535892841397964	0.408624514972845	NA	NA	0.441042693243127	0.287679894805225	77.0243286356164
a5021	gain_cnaOV72_(ASXL1)	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	0.102913780048539	0.938300434834669	-0.83538665478613	2.29429117572625	2.06073648352456	0.401958740329311	0.364115358863153	0.40538257145685	0.408663718800971	NA	NA	0.413171194830699	0.598494892359514	77.0243286356164
a5022	loss_cnaOV84	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	6	26	1.63315443905142	NA	2.96518730310003	2.84036271930198	0.124824583798047	0.84146094348187	0.80158326524129	0.154415893008101	0.148342694649067	0.155722542137245	0.409042943338689	NA	NA	0.0188721323172259	0.750433559305691	77.0243286356164
a5023	loss_cnaOV39	1203	QL-XII-61	BTK	7	16	2.30258509299405	NA	4.47386825120526	3.63679400318827	0.837074248016994	1.15067249037	1.57558942426581	0.570680773039345	0.72746524751611	0.531276889223252	0.409098094607039	NA	NA	0.067548681443812	0.173331684074898	77.0243286356164
a5024	loss_cnaOV35	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.16438400556895	3.72502776270256	-0.560643757133615	0.945814452386984	0.877212621795624	0.63146873279988	0.592762941736299	0.639119573981957	0.409250686096088	NA	NA	0.0578159670228738	0.335366655211421	77.0243286356164
a5025	gain_cnaOV4_(KRAS)	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.65849618710469	4.44019574562769	0.218300441477003	0.750719848599712	0.654722186259526	0.323071268590696	0.290788157372141	0.333424536480379	0.409269725724925	NA	NA	0.0521307279308263	0.504298355449226	77.0243286356164
a5026	loss_cnaOV38	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	3.77341813329242	3.19852093033844	0.574897202953977	1.06221664694355	0.936379323275177	0.598985080550679	0.541224056889148	0.613957601010622	0.40930404772424	NA	NA	0.185561776507812	0.376310628254208	77.0243286356164
a5027	gain_cnaOV95_(MECOM)	253	XMD14-99	EPHB3, CAMK1	9	23	2.32630161961136	NA	5.00813184061563	4.80212424863443	0.206007591981196	0.539283942146047	0.644441657379659	0.333264063103132	0.382002088104834	0.319668335561727	0.409335112502265	NA	NA	0.0484699572177882	0.371182075087794	77.0243286356164
a5028	loss_cnaOV42	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	1.58361873718356	0.921400464119071	0.662218273064486	0.989138383925915	1.59547778696397	0.42845792783804	0.66949001659012	0.415059537948578	0.409366582925397	NA	NA	0.789862235821293	0.299759929220323	77.0243286356164
a5029	loss_cnaOV42	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.204386948387255	-0.40662921843691	0.611016166824165	1.134173496132	1.42957825648378	0.435286518320744	0.53873253863539	0.427410086893063	0.409542974129141	NA	NA	0.888375662376357	0.379309256148346	77.0243286356164
a5030	loss_cnaOV83	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.45894028478448	4.87268761683892	0.586252667945558	1.22762729716986	1.22802986390272	0.477413707100073	0.477549390842881	0.477392842941481	0.409581999957118	NA	NA	0.369957167530524	0.367203081515166	77.0243286356164
a5031	loss_cnaOV52, loss_cnaOV53	1072	BMS-708163	g-secretase	9	24	1.6094379124341	NA	4.0362342287267	3.76830435376694	0.267929874959755	1.02186633634671	0.800319552199114	0.310479429412938	0.262196596002599	0.33477861964454	0.409616647334918	NA	NA	0.923333869730687	0.491856512314909	77.0243286356164
a5032	loss_cnaOV21, loss_cnaOV22	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.93417885266345	3.5040478954625	0.43013095720095	1.23814216948855	0.873446467495844	0.476675006290919	0.347400296832332	0.492452569456406	0.409642663496829	NA	NA	0.661511979218338	0.611720260295659	77.0243286356164
a5033	gain_cnaOV4_(KRAS)	309	Y-39983	ROCK	8	24	2.99573227355399	NA	5.2810451315757	4.85870441774865	0.422340713827043	1.50568943453937	1.13726947555498	0.342497886716828	0.280496564655944	0.371363799789793	0.409682881120502	NA	NA	0.369959592196594	0.484085734576558	77.0243286356164
a5034	SMARCA4_mut	1026	17-AAG	HSP90	3	30	0	NA	-1.90634500760258	-0.393280873358795	-1.51306413424379	0.280881056893828	2.34754823200822	0.666055437067874	5.38685004598129	0.644529519612653	0.409725822640431	NA	NA	0.0599750406677066	0.00254003107845179	77.0243286356164
a5035	loss_cnaOV35	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.71079899666654	2.21363907623651	0.497159920430022	1.44301934151869	1.40517196658142	0.352482525207404	0.344527551451107	0.353807172540982	0.409817234149101	NA	NA	0.527560698792158	0.507226755491998	77.0243286356164
a5036	gain_cnaOV72_(ASXL1)	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	1.49012004247184	0.549117405449191	0.941002637022646	2.80137507737747	2.2162245656498	0.408624984390602	0.335907406552489	0.424597151212761	0.409863599600586	NA	NA	0.945536935154124	0.509025015827905	77.0243286356164
a5037	gain_cnaOV48_(SOX17)	152	CP466722	ATM	3	29	2.77258872223978	NA	2.30577471731799	2.68220723339549	-0.376432516077505	0.432012835826645	0.833308142225696	0.463162995546435	0.871345675082111	0.45173267486873	0.409910248023155	NA	NA	0.553727798464321	0.272398284829202	77.0243286356164
a5038	loss_cnaOV35	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	1.90823996836259	1.5600731677707	0.348166800591893	0.902888270348777	0.634985163595919	0.514385152455026	0.385614490769051	0.548306985032887	0.409983845306929	NA	NA	0.206598825240787	0.448572510519389	77.0243286356164
a5039	loss_cnaOV44	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.15589791498092	0.271509892074593	0.884388022906325	1.6220212242931	1.67138340351799	0.530200377901128	0.545238255616388	0.529135338453662	0.409998255899052	NA	NA	0.836283925335699	0.449146443265494	77.0243286356164
a5040	loss_cnaOV57_(ZNRF3)	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.00083017790295	2.44963382317273	-0.448803645269781	1.45667663030537	0.861210236158476	0.478506383472968	0.308101081552806	0.521131341020422	0.410003329927068	NA	NA	0.733383210284455	0.586349825251119	77.0243286356164
a5041	loss_cnaOV33_(ZFHX3)	308	XL-880	MET	4	28	1.63315443905142	NA	-0.181944711273719	0.315247416705878	-0.497192127979597	0.509629761725403	1.00218591520993	0.515588836292194	0.975594765690887	0.496107678659051	0.410098508196138	NA	NA	0.365664931637605	0.161372554317529	77.0243286356164
a5042	loss_cnaOV85	281	CH5424802	ALK	7	25	1.63315443905142	NA	4.13263646999954	3.87019702737389	0.262439442625649	0.60706668647597	0.754070392150362	0.360964091114401	0.432307435858676	0.348030429728526	0.410124217187917	NA	NA	0.955542553460985	0.358416973651866	77.0243286356164
a5043	gain_cnaOV94	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	7	26	0.693147180559945	NA	3.06747046353114	2.72528047999401	0.342189983537133	1.02089979075641	0.943808186261642	0.356740423279747	0.335184693576632	0.36256305944169	0.410130532674071	NA	NA	0.9660119272954	0.444622285590723	77.0243286356164
a5044	loss_cnaOV87, loss_cnaOV88	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	3.11171084131612	2.30585392638384	0.805856914932275	2.1565303494554	1.21414265300965	0.621903038994777	0.373682158072008	0.663725068001439	0.410196086770966	NA	NA	0.108216182921666	0.585721667536498	77.0243286356164
a5045	loss_cnaOV1	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.99233146253533	4.23944650351916	0.752884959016169	0.423026278665931	1.34113901953486	0.578431323778984	1.77975931280319	0.56137726816515	0.410312593446646	NA	NA	0.368560647689439	0.0632968633938898	77.0243286356164
a5046	loss_cnaOV43_(NF1)	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.728905981558363	0.330929447347809	0.397976534210554	0.38616866712875	0.950500012279926	0.438047116733253	1.03057696827036	0.418702292550153	0.410365596243236	NA	NA	0.909135216214429	0.165810840259213	77.0243286356164
a5047	gain_cnaOV48_(SOX17)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.301731046678149	-0.395996422705194	0.697727469383343	0.316581176335829	1.44874120834114	0.497121924869189	2.20394490114344	0.481609458864132	0.410386692421361	NA	NA	0.888380258823837	0.0468120994162931	77.0243286356164
a5048	loss_cnaOV102	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.49344542141521	1.16538743126816	1.32805799014705	0.972653766942334	2.37914682268108	0.574381401521458	1.36539643939485	0.558207663976975	0.410421591432666	NA	NA	0.360853706145325	0.121010309429172	77.0243286356164
a5049	loss_cnaOV52, loss_cnaOV53	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.10470371989831	3.70494339953826	-0.600239679639954	1.11622793266315	0.861797693104805	0.674034341941891	0.537739347023754	0.696497199333948	0.410492923151666	NA	NA	0.0578381273349912	0.453611146408108	77.0243286356164
a5050	loss_cnaOV55	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.10470371989831	3.70494339953826	-0.600239679639954	1.11622793266315	0.861797693104805	0.674034341941891	0.537739347023754	0.696497199333948	0.410492923151666	NA	NA	0.0578381273349912	0.453611146408108	77.0243286356164
a5051	loss_cnaOV70	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.67372371131078	-4.13272616521655	-0.54099754609423	1.25955583552507	1.34616123869408	0.403560370715318	0.429514540630671	0.401881684410298	0.410568972690772	NA	NA	0.21525362134101	0.54157854071265	77.0243286356164
a5052	gain_cnaOV4_(KRAS)	1371	PLX4720 (rescreen)	BRAF	7	26	2.30258509299405	NA	4.80820987797202	4.45290964140664	0.355300236565384	0.852775996986966	1.01402314443696	0.360756122840027	0.416639583924422	0.350386713079084	0.410576449678183	NA	NA	0.322964277544768	0.368223590249217	77.0243286356164
a5053	NF1_mut	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.65276987871153	4.46529969222042	0.187470186491106	0.227471291591578	0.713099338735509	0.276032266436934	0.824148775783571	0.262894910018476	0.410600862500213	NA	NA	0.0521461497117032	0.310066572589456	77.0243286356164
a5054	BRCA1_mut	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.8451645197184	3.52207384474057	0.323090674977831	0.621513062923396	0.944453733127122	0.351881996904031	0.519845348797847	0.342092644292977	0.410625056768297	NA	NA	0.140851179822478	0.405525995895673	77.0243286356164
a5055	loss_cnaOV42	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.01629838609391	2.50013113351518	-0.483832747421273	2.88189395143022	1.20362798499531	0.331176439015031	0.167887075505036	0.401978645771647	0.410762906442685	NA	NA	0.237588533716118	0.760983868261875	77.0243286356164
a5056	loss_cnaOV39	1016	Temsirolimus	MTOR	10	21	-1.6094379124341	NA	-1.47358559851889	-2.2940114492112	0.820425850692311	1.18068986425584	1.6542277499556	0.538653389161904	0.694869902359506	0.495957011188049	0.411367357131199	NA	NA	0.0368404468072117	0.127155954350929	77.0243286356164
a5057	loss_cnaOV84	295	NVP-BHG712	EPHB4	6	26	2.32630161961136	NA	2.80329929754867	3.35447524916816	-0.551175951619492	0.900805764084312	1.10436881484524	0.513616923311492	0.611869920903286	0.499086848714332	0.411467277350006	NA	NA	0.0610350007508619	0.229233756405589	77.0243286356164
a5058	RB1_mut	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	4.51567081474704	5.02659886620222	-0.510928051455186	0.660648704743709	0.829921617608896	0.626662662965233	0.773373273551477	0.615634104010004	0.411473496977537	NA	NA	0.450495134967017	0.313698470545887	77.0243286356164
a5059	gain_cnaOV96	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-1.7000868557189	-1.24653094380973	-0.453555911909172	0.94238432948755	1.98491031244736	0.241302140142794	0.481285498620087	0.22850196760273	0.411608724938664	NA	NA	0.0726364737573153	0.440691090813271	77.0243286356164
a5060	loss_cnaOV54	135	Gemcitabine	DNA replication	6	13	0.0237165266173161	NA	-3.08593310936187	-1.75075601932022	-1.33517709004166	0.828444916483533	3.06557019551227	0.510684083041855	1.611666706471	0.435539558675329	0.411701567137243	NA	NA	0.412215366579183	0.164897696364201	77.0243286356164
a5061	gain_cnaOV48_(SOX17)	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.638194208596783	0.398796884204407	-1.03699109280119	0.827670526286531	1.88678810516274	0.566178723060741	1.2529032505891	0.549606545623069	0.411705560089951	NA	NA	0.483508733046846	0.146377274141293	77.0243286356164
a5062	gain_cnaOV94	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	3.84071162975995	3.22183447493541	0.61887715482454	0.643226399978608	0.996956156892068	0.6432466640247	0.962145140257183	0.62076667117824	0.411889970247228	NA	NA	0.18566211125806	0.237060137807497	77.0243286356164
a5063	gain_cnaOV96	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	3.07194513466628	2.24348978901194	0.82845534565434	1.2928853179533	1.56489534298315	0.53772334105672	0.640780225554595	0.529399840934449	0.411966426977546	NA	NA	0.239731161822612	0.30292666471694	77.0243286356164
a5064	NF1_mut	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	0.324260753236693	0.68493089110966	-0.360670137872968	1.07414439152559	0.534106583952777	0.591245459203421	0.335774352795079	0.675277460921276	0.411972103264936	NA	NA	0.0146047807229374	0.553486298664177	77.0243286356164
a5065	loss_cnaOV55	282	EKB-569	EGFR	7	25	0.916290731874155	2.99573227355399	1.37995234507884	1.76863188344642	-0.388679538367574	1.98392601226719	1.3343382844722	0.261361956773557	0.195914331464105	0.291290104533962	0.412197433207895	NA	NA	0.323841895405178	0.639113228488285	77.0243286356164
a5066	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.46506078635336	2.7189084448996	0.746152341453768	0.952587975019461	1.23515517096069	0.612424587681419	0.783289691892788	0.604096035053973	0.412218824786796	NA	NA	0.0930759456657916	0.306423853293777	77.0243286356164
a5067	NF1_mut	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.22097423718603	4.64093190095003	-0.419957663764	1.25275625059527	0.900167356119317	0.446104856906517	0.33522695541487	0.466532874036298	0.412252240379457	NA	NA	0.942831106002677	0.558046259512556	77.0243286356164
a5068	gain_cnaOV48_(SOX17)	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	1.52490791935072	1.937954982026	-0.413047062675279	0.531442817425721	1.42566018109162	0.298122185848837	0.777218261554565	0.289723363360694	0.412296510819474	NA	NA	0.0333958636976879	0.34613250200971	77.0243286356164
a5069	PTEN_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-2.32469442432034	-2.0958353564911	-0.228859067829241	1.05575210045351	1.32514919808715	0.175840132451652	0.216773490415916	0.17270437786145	0.412322645364056	NA	NA	0.605660423037349	0.712569781284994	77.0243286356164
a5070	loss_cnaOV70	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.24451369704539	4.70396981087662	0.540543886168768	0.911244356264059	1.24759867304127	0.440410163968352	0.593193123724686	0.433267442366771	0.41238747583609	NA	NA	0.422284933539367	0.420325937763586	77.0243286356164
a5071	loss_cnaOV42	263	FR-180204	ERK	4	28	2.99573227355399	NA	5.08753341314143	4.77236978251028	0.315163630631143	0.555656889855593	0.76388529184042	0.422650578095293	0.567191078496389	0.412579786517192	0.412432771542733	NA	NA	0.763968277813922	0.362141058215992	77.0243286356164
a5072	BRCA1_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.75934898846439	1.1411228737473	0.618226114717094	1.10278971416797	1.24428682269394	0.502090393057698	0.560601995806182	0.496851773595582	0.412464957629499	NA	NA	0.264488970722858	0.35777315266283	77.0243286356164
a5073	ARID1A_mut	238	CAL-101	PI3Kdelta	8	24	2.99573227355399	2.32630161961136	4.06363786571114	4.49508348027171	-0.43144561456057	1.0104544881515	0.963487086615652	0.442667860597876	0.426981739028983	0.447795949270132	0.412468709379105	NA	NA	0.509197517961561	0.311673954661174	77.0243286356164
a5074	gain_cnaOV26	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	6.0495771595452	5.69304992738052	0.356527232164674	0.647743480739477	0.596295770057394	0.594347852716296	0.550414234594311	0.59790333936187	0.412539636463182	NA	NA	0.190006623267621	0.44405960326901	77.0243286356164
a5075	loss_cnaOV55	292	Masitinib	KIT	7	25	2.99573227355399	NA	4.40462343512396	3.90401157625013	0.500611858873835	1.03244891338622	1.03814181250319	0.482747436197134	0.484878091674225	0.482219146598816	0.412604848880238	NA	NA	0.102896621407064	0.284671281590021	77.0243286356164
a5076	loss_cnaOV16, loss_cnaOV17	1020	Lenalidomide	TNFA	6	25	1.6094379124341	NA	4.7384985127975	4.31866719308732	0.419831319710185	0.808682772093058	0.748582748453971	0.552930340083076	0.519154524120211	0.560834885090863	0.412651566753742	NA	NA	0.0420031672401742	0.283753398603391	77.0243286356164
a5077	gain_cnaOV95_(MECOM)	184	BMS-754807	IGF1R	5	12	0.940007258491471	NA	0.534037893034576	0.915483392420746	-0.38144549938617	0.737337605035583	1.16952701110241	0.356005390426361	0.517328150335913	0.32615364652982	0.412709774471715	NA	NA	0.349922001907437	0.434678712022581	77.0243286356164
a5078	MLL2_mut	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.11875785582602	-0.135959352020525	0.254717207846545	1.60719936090094	1.23916901399649	0.200883535807506	0.15848513510095	0.205554855689174	0.412795221099937	NA	NA	0.765862762215455	0.812447489010839	77.0243286356164
a5079	loss_cnaOV1	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	2.158631863626	1.32870994241323	0.82992192121277	2.10065819065232	1.39810041841145	0.569427926859746	0.39507708817447	0.593606804120512	0.412811786759906	NA	NA	0.473986786441279	0.567204995181108	77.0243286356164
a5080	gain_cnaOV50	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	3.96779878768412	3.29042996922784	0.677368818456283	1.85174279312416	1.64473071648028	0.406440124437247	0.365800704596486	0.411841775476687	0.412884848349324	NA	NA	0.627914174453351	0.528928328111574	77.0243286356164
a5081	gain_cnaOV96	1248	FK866	NAMPT	4	28	0	NA	-0.290756087821372	-1.91087227229671	1.62011618447534	1.04681579660535	2.85099623746145	0.594565316701608	1.54766119285657	0.568263178739901	0.412944218997	NA	NA	0.0435077718406173	0.053336231001663	77.0243286356164
a5082	loss_cnaOV56	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.46165989150063	1.47256081403615	0.98909907746448	0.785806102038173	1.65042269526803	0.615372721709371	1.25870628250279	0.599300458179806	0.412990638176028	NA	NA	0.0772960654055204	0.14203827859217	77.0243286356164
a5083	KRAS_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	7	24	2.30258509299405	NA	4.29570771494073	4.57465227926974	-0.27894456432901	1.01497518920282	0.895990917647049	0.302585840145516	0.274828948821989	0.311325214167955	0.413026236025213	NA	NA	0.526124882916929	0.528168325173721	77.0243286356164
a5084	loss_cnaOV35	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-2.64369098033521	-2.23656952350213	-0.407121456833072	1.61472844981415	1.6228153485955	0.251034620581212	0.252129983143562	0.250873555753231	0.41304355942806	NA	NA	0.122447138644879	0.623856567291677	77.0243286356164
a5085	loss_cnaOV87, loss_cnaOV88	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.07241531721728	2.48350752495887	0.588907792258405	1.36115742753014	1.0020038631309	0.572330233697154	0.432652226955847	0.58773006165693	0.413095541570548	NA	NA	0.392691761605349	0.534692485174016	77.0243286356164
a5086	TP53_mut	1262	UNC1215	LMBL3	23	10	0	NA	2.81730790231898	2.69555374964678	0.121754152672203	0.535456208774249	0.380341876680057	0.245743911833291	0.227383959093347	0.320117662916782	0.413123774033183	NA	NA	0.107938510694487	0.465363124626726	77.0243286356164
a5087	TP53_mut	1502	Bicalutamide	ANDR (androgen receptor)	22	10	2.30258509299405	NA	4.57182444267024	4.39372164355439	0.178102799115859	0.642555919969128	0.478371037656745	0.297804814475483	0.27717867594219	0.37231099940389	0.413139568545914	NA	NA	0.613146258339716	0.391799000259245	77.0243286356164
a5088	loss_cnaOV21, loss_cnaOV22	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.07225858735382	2.48352319794522	0.588735389408598	0.755920583986747	1.04517877454735	0.572157857702055	0.778832329586251	0.563286782841119	0.41325338135264	NA	NA	0.39269534652952	0.309120803529847	77.0243286356164
a5089	SMARCA4_mut	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-4.34384457315727	-3.20497484448994	-1.13886972866733	0.882746584477751	1.85517132363962	0.630950770421644	1.29014345531692	0.613889247939113	0.4132857657654	NA	NA	0.13733696982707	0.13489046276123	77.0243286356164
a5090	PTEN_mut	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.67244059710335	5.24442267201206	-0.571982074908706	0.9095619560991	0.746440318389371	0.754188403118047	0.628854440396567	0.766279715628034	0.41344661214979	NA	NA	0.331046260227493	0.390651756832856	77.0243286356164
a5091	gain_cnaOV19	333	T0901317	LXR	3	29	2.32630161961136	NA	5.40317563149228	4.68612859140062	0.717047040091659	0.485324772145269	1.1395139565908	0.64716370006661	1.47745815018284	0.629256917780035	0.413559240374079	NA	NA	0.00490643682937172	0.0987168246639124	77.0243286356164
a5092	loss_cnaOV70	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.655517229295574	-0.0530013071860683	-0.602515922109506	1.1248587429661	1.26618799979918	0.479347021286914	0.535636964087378	0.475850286217424	0.413846155695918	NA	NA	0.765875184295575	0.457493532331663	77.0243286356164
a5093	loss_cnaOV70	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.282105449912853	-1.42449839350754	1.14239294359468	1.57645783476917	1.87405425856331	0.615612987246424	0.724658102740793	0.60958370782203	0.413889785650874	NA	NA	0.0726675449785407	0.336442905275012	77.0243286356164
a5094	gain_cnaOV72_(ASXL1)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	1.64327219397441	1.05285843710324	0.590413756871163	1.73559311693391	1.54677968244619	0.373268922040771	0.340179821589857	0.381705141056314	0.414104996966532	NA	NA	0.530483389467426	0.567353713264277	77.0243286356164
a5095	loss_cnaOV70	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	4.23078111815108	3.80243563981645	0.428345478334626	0.369800973623615	0.886321689321304	0.496698891813243	1.15831354941374	0.483284436672908	0.414265823889498	NA	NA	0.923351204839619	0.172563335128793	77.0243286356164
a5096	gain_cnaOV94	254	AC220	FLT3	7	25	0.0237165266173161	NA	2.67593426250444	2.46458732490938	0.211346937595061	0.504688567500809	0.65539821418563	0.336456299668937	0.418767040120682	0.322471030620172	0.414341784325484	NA	NA	0.85735320227696	0.378694043116577	77.0243286356164
a5097	KRAS_mut	1049	PD-173074	FGFR1, FGFR3	7	26	0.693147180559945	NA	2.6097607685449	3.08794238035769	-0.478181611812786	0.890634976594629	1.01735870645275	0.481022977571497	0.536899655166394	0.470022627004466	0.414343113423184	NA	NA	0.0861607314609367	0.248091713287369	77.0243286356164
a5098	loss_cnaOV41	306	TG101348	JAK2	5	27	2.32630161961136	NA	3.34362329437354	2.72784293747905	0.615780356894489	1.05225181761717	1.43420571701936	0.443211916567062	0.585202464452781	0.429352881240938	0.414566957876061	NA	NA	0.625619305334739	0.295722454366371	77.0243286356164
a5099	loss_cnaOV42	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.56042698193712	5.73716576405219	-0.176738782115065	0.547421811039477	0.469785778231331	0.36965591906301	0.322856668387879	0.376211435732384	0.414617660573974	NA	NA	0.379217616753918	0.575185471735632	77.0243286356164
a5100	gain_cnaOV95_(MECOM)	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-4.51853903449098	-4.07174656872018	-0.446792465770798	1.06990041137621	1.40648086950995	0.334537153717077	0.417601919786246	0.317666934159206	0.414622249613973	NA	NA	0.215344863373407	0.360949166036859	77.0243286356164
a5101	loss_cnaOV55	262	VX-11e	ERK	7	25	1.63315443905142	NA	2.48998947924617	2.96267825755204	-0.472688778305876	1.18670728557803	1.09177064443818	0.425306670802921	0.398319605896442	0.432956116482799	0.414726435685988	NA	NA	0.388282321268423	0.367966824586149	77.0243286356164
a5102	loss_cnaOV57_(ZNRF3)	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.89573968405011	4.37945636226551	0.516283321784607	1.26376482568795	0.970787400795846	0.51479676244766	0.408528004016539	0.531819141205748	0.414851555498037	NA	NA	0.372507969961965	0.481718966154861	77.0243286356164
a5103	loss_cnaOV40	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	1.22802981594379	0.76879504423001	0.45923477171378	1.91405883703429	1.00492701328934	0.369986627340964	0.239927197026678	0.456983209368216	0.414863399764288	NA	NA	0.844077136331324	0.560249042003476	77.0243286356164
a5104	loss_cnaOV43_(NF1)	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.45913290113108	1.74853472821318	0.710598172917903	1.94320701556053	1.62499689883398	0.426634057278954	0.365683206795611	0.437292017866491	0.414921241689959	NA	NA	0.341264011390581	0.600081871658639	77.0243286356164
a5105	loss_cnaOV52, loss_cnaOV53	1061	SB590885	BRAF	9	24	1.6094379124341	NA	3.57940588450334	4.05809005166354	-0.4786841671602	1.70064929808828	1.08879672184904	0.375403961166951	0.281471416651449	0.439645121586404	0.41498457532906	NA	NA	0.571180173702909	0.449056198641968	77.0243286356164
a5106	gain_cnaOV19	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.8574421933744	2.42368124634174	0.43376094703266	0.476399320362377	0.795080797336511	0.567367460605201	0.910498668853508	0.545555808272244	0.415207400327613	NA	NA	0.746876043500043	0.263498394952429	77.0243286356164
a5107	loss_cnaOV81_(RB1)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.58348440631139	1.16538005749254	0.418104348818853	0.94317119020427	1.26857240621006	0.336958876517813	0.443296352943415	0.329586507456808	0.415212639726561	NA	NA	0.264551271833174	0.466192222372475	77.0243286356164
a5108	gain_cnaOV49	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.25372037913639	8.80270986699723	-0.548989487860837	1.13466031913342	1.24132697226128	0.444790025224582	0.483835980340017	0.442260178122742	0.415215880365941	NA	NA	0.527676068340029	0.497034971643525	77.0243286356164
a5109	loss_cnaOV83	1009	ATRA	Retinoic acid and retinoid X receptor agonist	5	26	2.30258509299405	NA	4.77325921007679	4.46135817910288	0.31190103097391	1.15916315283157	0.878283033100423	0.338241299864969	0.269074314700229	0.355125875394484	0.415225862721425	NA	NA	0.526171805017307	0.593093656902616	77.0243286356164
a5110	gain_cnaOV72_(ASXL1)	308	XL-880	MET	5	27	1.63315443905142	NA	-0.0390689379822744	0.307203463428929	-0.346272401411204	0.482721185784477	1.0251568276879	0.356794272313665	0.717334170549136	0.337775052615288	0.415365128897778	NA	NA	0.365790297315549	0.259017161334703	77.0243286356164
a5111	KRAS_mut	170	Shikonin	unknown	3	15	2.77258872223978	NA	-0.271688479048694	0.0408004546609482	-0.312488933709642	0.305664748127528	0.840260970013922	0.393867088543746	1.02232572000507	0.371895095525459	0.415478407755274	NA	NA	0.580278885669808	0.291269213245352	77.0243286356164
a5112	gain_cnaOV4_(KRAS)	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-3.49886038542711	-4.3496828835772	0.850822498150098	3.50413869258065	1.89871002994569	0.363992103132271	0.24280502936472	0.448105547835776	0.415592616467191	NA	NA	0.927634574164952	0.557424528987527	77.0243286356164
a5113	loss_cnaOV38	1019	Bosutinib	SRC, ABL, TEC	8	23	0.693147180559945	NA	2.34417403888821	1.50760732575436	0.83656671313385	0.980693375998925	1.71253700593895	0.533698950541047	0.853035957627154	0.488495553808587	0.415628021253642	NA	NA	0.0402027157532496	0.107022970007242	77.0243286356164
a5114	gain_cnaOV18_(CCNE1)	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.66152672162933	2.31873701973461	0.342789701894725	0.666381915447232	0.889769635310103	0.394003996908598	0.514404268706282	0.385256687002199	0.415676017930506	NA	NA	0.606031572647269	0.403146245018112	77.0243286356164
a5115	SMARCA4_mut	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	0.975840696346918	0.026170463456272	0.949670232890646	2.37028379820022	1.53995140153977	0.589485895664594	0.400656762541153	0.616688443506132	0.415802973187628	NA	NA	0.45944952062155	0.562069558179513	77.0243286356164
a5116	loss_cnaOV38	308	XL-880	MET	8	24	1.63315443905142	NA	-0.0459338094590503	0.352775804097588	-0.398709613556639	0.416246218753563	1.07533399098635	0.414120601796439	0.957869634829508	0.370777467185729	0.415811449052706	NA	NA	0.365800813212074	0.142172851461721	77.0243286356164
a5117	loss_cnaOV33_(ZFHX3)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.18243753389738	3.78436020507949	0.398077328817894	1.35194759650013	0.773109501353951	0.452646596867688	0.294447306869305	0.514904199367282	0.415843930339047	NA	NA	0.939396955701541	0.604190873804387	77.0243286356164
a5118	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.10899367579918	3.70426603808023	-0.595272362281051	1.2563566455054	0.840600525578585	0.668132336504799	0.473808424073397	0.708151308698416	0.415971222483949	NA	NA	0.0579347521741169	0.501530037748224	77.0243286356164
a5119	gain_cnaOV26	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.66009368502854	5.16922512055291	0.490868564475633	0.347998387719324	0.76394777736438	0.672848430678009	1.41054838699868	0.642542041511174	0.416017034585349	NA	NA	0.123247018225613	0.12042169947166	77.0243286356164
a5120	loss_cnaOV52, loss_cnaOV53	294	MPS-1-IN-1	MPS1	8	23	2.99573227355399	NA	4.42579464317746	4.23447695036834	0.191317692809126	0.475662234104613	0.904172332945744	0.232897859690624	0.402213333520713	0.211594278920064	0.416059317006534	NA	NA	0.314279124443021	0.456339138376014	77.0243286356164
a5121	loss_cnaOV58	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.61932554658091	2.31385613726599	0.30546940931492	0.849252252364667	0.87355409568148	0.35097183517504	0.359692198006384	0.349685738782572	0.416118452219411	NA	NA	0.606039473544179	0.491258010015852	77.0243286356164
a5122	gain_cnaOV50	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.03505795482035	5.15777929459772	-0.122721339777363	0.788399597314323	0.563803416082383	0.207959185336968	0.155658805757147	0.217666896433687	0.41626757220568	NA	NA	0.0114925113894029	0.780979824917377	77.0243286356164
a5123	ARID1A_mut	205	BMS-708163	g-secretase	8	24	2.32630161961136	0.940007258491471	4.74903732371941	5.16632700434552	-0.417289680626107	0.690709331977252	0.5613232121244	0.702461364530794	0.604146579910187	0.743403571441167	0.416391905077858	NA	NA	0.108794625066228	0.152110431917795	77.0243286356164
a5124	loss_cnaOV82	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.90466251381076	0.218770230376923	0.685892283433837	1.41998845279956	1.10709110080076	0.607040261552396	0.483026662703893	0.619544573104896	0.416403459925667	NA	NA	0.144839619590709	0.493600220272707	77.0243286356164
a5125	gain_cnaOV49	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	-0.346492195307861	0.804008508462446	-1.15050070377031	1.92730595023801	2.32840911883707	0.499383399446857	0.596947621952926	0.49411449837687	0.416407941206816	NA	NA	0.945554829358322	0.414787175645785	77.0243286356164
a5126	gain_cnaOV95_(MECOM)	1114	Cetuximab	EGFR	8	24	4.18661983833127	NA	5.48403336458141	5.93516830330749	-0.451134938726077	1.35033915756562	1.25970626704788	0.352056563281556	0.33409009595736	0.3581270892486	0.416431102282993	NA	NA	0.568949310561823	0.422580673293808	77.0243286356164
a5127	loss_cnaOV1	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.59590102869894	4.89895048249919	0.69695054619975	0.524399301815665	1.26515276478648	0.566750646813596	1.32904552654179	0.550882522331106	0.416443024123247	NA	NA	0.370120088251159	0.128583245235946	77.0243286356164
a5128	gain_cnaOV72_(ASXL1)	1114	Cetuximab	EGFR	5	27	4.18661983833127	NA	6.27683688110945	5.73822673298088	0.538610148128561	0.784238021988922	1.34162422037449	0.420332077185637	0.686794229591905	0.401461258636355	0.416547954905157	NA	NA	0.568951541822356	0.247155354616797	77.0243286356164
a5129	RB1_mut	1061	SB590885	BRAF	3	30	1.6094379124341	NA	3.41412081242876	3.97888172543896	-0.564760913010201	1.57223274307066	1.26067541413211	0.440166877156521	0.359209484409536	0.44798280880174	0.416818730893935	NA	NA	0.571213955649562	0.601356754534505	77.0243286356164
a5130	gain_cnaOV51_(MYC)	268	YM155	BIRC5 (Survivin)	6	24	1.63315443905142	NA	-4.86946531966873	-3.97158071259388	-0.897884607074855	1.34658589010188	2.50160674379084	0.384106784019787	0.6667859909084	0.358923163804009	0.416889035391935	NA	NA	0.927639577804042	0.250083752465671	77.0243286356164
a5131	ARID1A_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	23	3.68887945411394	NA	3.35479388104256	3.53650372678607	-0.181709845743514	1.22432790762808	1.08522771593349	0.162185048485601	0.148415995920199	0.167439370627584	0.416914759696413	NA	NA	0.725379859857477	0.716893300885626	77.0243286356164
a5132	NF1_mut	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.58236871940785	4.23445046585599	0.34791825355186	0.580290372504853	0.92378008930653	0.388570248280934	0.59955889333482	0.37662454254999	0.416948302527071	NA	NA	0.519388975874733	0.347356839898232	77.0243286356164
a5133	loss_cnaOV83	1018	ABT-888	PARP1, PARP2	5	26	1.6094379124341	NA	4.63940201374309	4.23423540692384	0.405166606819247	0.749824496702887	0.800006558149851	0.510752634744587	0.540348586370327	0.506454106771652	0.41695952532536	NA	NA	0.222666188624411	0.316452216236472	77.0243286356164
a5134	PTEN_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	0.655100425120475	1.52071749177653	-0.865617066656059	1.13682772182884	1.48039486293063	0.59753897920298	0.761432053454432	0.584720393410756	0.416979921905723	NA	NA	0.474081348978479	0.23546750675488	77.0243286356164
a5135	gain_cnaOV26	262	VX-11e	ERK	3	29	1.63315443905142	NA	3.29734357548864	2.81396041610546	0.483383159383181	1.25489677800717	1.10992077987284	0.431526705417832	0.385197546009173	0.435511405992921	0.41700752412986	NA	NA	0.388335528392758	0.578361692631511	77.0243286356164
a5136	gain_cnaOV96	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-4.57553888166787	-4.12743122851932	-0.448107653148553	0.678987857775609	1.39606600896741	0.333980918033748	0.659964162859365	0.320978843600663	0.417057740535514	NA	NA	0.215399061236295	0.33008692984325	77.0243286356164
a5137	loss_cnaOV38	1259	BMN-673	PARP1	8	25	2.30258509299405	NA	1.79419332844639	1.93439306365045	-0.140199735204059	1.33013846358518	1.40636726709355	0.10089796894751	0.105402361515186	0.099689276396343	0.417088898600098	NA	NA	0.0334338104331928	0.802246947912675	77.0243286356164
a5138	loss_cnaOV81_(RB1)	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	2.22449605118577	2.82395058000307	-0.599454528817303	0.732773548174479	1.75543928915376	0.35652106248473	0.818062456417393	0.341484056168231	0.417117902558894	NA	NA	0.318832358490661	0.255275179996757	77.0243286356164
a5139	PIK3R1_mut	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.07390922111669	3.7504467377111	0.323462483405583	0.960780890555239	1.04319032122884	0.313255833779874	0.336666233253924	0.310070441436376	0.417175180626216	NA	NA	0.715783051335417	0.521104280367714	77.0243286356164
a5140	loss_cnaOV57_(ZNRF3)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-2.71342326018386	-2.24098994893105	-0.472433311252816	1.93042448496939	1.58422684258987	0.291451971486182	0.244730273020914	0.298210646702898	0.417344173150372	NA	NA	0.122521656004274	0.666707936890723	77.0264125053959
a5141	loss_cnaOV54	256	JW-7-24-1	LCK	10	22	2.32630161961136	NA	1.67447412998585	2.05973969543515	-0.385265565449296	1.23014823153679	1.38492284507689	0.287432605131576	0.313186293791599	0.278185580387263	0.417348828126211	NA	NA	0.838223273791797	0.439636704552768	77.0264125053959
a5142	gain_cnaOV96	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.62220262942275	2.30778952382612	0.314413105596627	0.745444116912236	0.884034604191172	0.362713042170044	0.421779578728158	0.355657011734616	0.417439285091575	NA	NA	0.648872724797633	0.431646771206283	77.0281242526744
a5143	loss_cnaOV55	277	ABT-869	VEGFR and PDGFR family	7	25	0.0237165266173161	NA	2.92281245535058	2.65813842149052	0.264674033860052	0.560364779575007	0.5635327593125	0.470196760671171	0.472324534851719	0.469669295149672	0.4175491043915	NA	NA	0.133658107180043	0.296604730785339	77.0334074808787
a5144	ARID1A_mut	1039	SL 0101-1	RSK, AURKB, PIM3	9	24	2.30258509299405	NA	4.80855876481402	4.98607715561102	-0.177518390796997	0.540248627342996	0.898917944329547	0.216093402035897	0.328586472621047	0.1974800836014	0.417740817060127	NA	NA	0.945707044545224	0.496473899769592	77.0537341952846
a5145	loss_cnaOV70	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	4.7385641417159	4.14101039382556	0.597553747890339	0.455936923545104	0.991642225311224	0.61908346109554	1.31060617605634	0.602590059840179	0.417829330225821	NA	NA	0.0470632213985242	0.1304331918031	77.0537341952846
a5146	loss_cnaOV38	1199	Tamoxifen	ER	8	24	1.6094379124341	NA	4.20432540457533	3.9050186094252	0.299306795150129	1.13969922088695	0.591838454794337	0.395878519066143	0.262619110081692	0.50572380474016	0.417999174875559	NA	NA	0.523452814743877	0.496289305354263	77.0537341952846
a5147	PIK3R1_mut	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	3.68770681864131	3.5386523386837	0.149054479957611	0.840564825074132	0.934545278611723	0.161496728086732	0.17732657316997	0.159494123365572	0.418010804514432	NA	NA	0.140988115440554	0.732141003763653	77.0537341952846
a5148	loss_cnaOV87, loss_cnaOV88	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.83039728410149	3.16755827476522	0.662839009336269	0.393536822243664	1.26362849435564	0.541091941020981	1.68431255189092	0.52455212295151	0.418107803075957	NA	NA	0.599054092514279	0.077383852781048	77.0537341952846
a5149	loss_cnaOV56	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.290834480337449	-0.394906766071124	0.685741246408573	1.24224209858854	1.41453078816045	0.488401076951859	0.55201900433718	0.484783542463826	0.418378025042249	NA	NA	0.888423104608398	0.445103304353357	77.0537341952846
a5150	loss_cnaOV102	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.55581790583044	3.01906043112357	0.536757474706869	1.21224943285306	0.887978194980341	0.588302511219953	0.442778078636502	0.604471458579849	0.4184756029511	NA	NA	0.23659825157849	0.526081880522419	77.0537341952846
a5151	loss_cnaOV56	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.542300778372815	-0.0138228556821174	-0.528477922690698	1.6104300585418	0.894798699422822	0.550920614959074	0.328159499934582	0.590610964266696	0.418712257237849	NA	NA	0.546902228826076	0.629071088855215	77.0537341952846
a5152	loss_cnaOV21, loss_cnaOV22	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.82802791543166	4.37234972090547	0.455678194526191	0.16185714597403	0.980720826741107	0.480476772505256	2.81531094462338	0.464635992324533	0.418747353882476	NA	NA	0.785386092361229	0.0362331545651232	77.0537341952846
a5153	loss_cnaOV52, loss_cnaOV53	268	YM155	BIRC5 (Survivin)	8	22	1.63315443905142	NA	-4.74177662051576	-3.93638709346088	-0.805389527054876	0.997068175569581	2.6376992662094	0.344465844174352	0.807757730904201	0.305337889490446	0.418786209932602	NA	NA	0.92764685799728	0.235147018171414	77.0537341952846
a5154	loss_cnaOV81_(RB1)	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.84606202979295	4.3521244576639	0.493937572129059	0.449853338599782	0.7818757462362	0.646831366641424	1.09799690198253	0.631734101622642	0.418854851219906	NA	NA	0.0420642524970964	0.184282404806036	77.0537341952846
a5155	gain_cnaOV18_(CCNE1)	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	2.34729762339254	1.45357331385643	0.893724309536115	2.3469005748464	1.50116517571327	0.556522633715372	0.380810469397328	0.595353745207597	0.418903201376897	NA	NA	0.0773786661858734	0.507480751292259	77.0537341952846
a5156	loss_cnaOV59	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.62741009751212	2.24667127313547	-0.619261175623347	1.74685428175785	1.23276435834231	0.478030910988484	0.354500762937243	0.502335398839777	0.418912029857015	NA	NA	0.684956624177931	0.536926178105764	77.0537341952846
a5157	ARID1A_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	0	NA	-1.20930770550502	-2.2824884210741	1.07318071556909	0.799958080863954	2.26112139624474	0.539401543118623	1.34154619003293	0.474623218970649	0.418935737408421	NA	NA	0.275986708751546	0.0528358766302902	77.0537341952846
a5158	loss_cnaOV40	1259	BMN-673	PARP1	8	25	2.30258509299405	NA	1.79546531270123	1.9339860286889	-0.138520715987668	1.18470049524208	1.44383691751685	0.0996872622337544	0.116924671293704	0.0959393088700765	0.418970151281972	NA	NA	0.0334485382632945	0.789302819561722	77.0537341952846
a5159	gain_cnaOV18_(CCNE1)	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	2.97868869147265	1.90807641257021	1.07061227890244	1.27917676231413	2.03284887544071	0.543321079091763	0.836954133661413	0.526656108989083	0.419020756361245	NA	NA	0.130546413193575	0.205857605174193	77.0537341952846
a5160	loss_cnaOV42	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.60509712264537	1.80320636993968	0.801890752705694	0.90389080205439	1.40485712817434	0.587707254238764	0.887154455917831	0.570798792719782	0.419071257182428	NA	NA	0.033449327135634	0.182019225228262	77.0537341952846
a5161	RB1_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	3.2282462214106	2.75482823534435	0.473417986066252	0.988913225154372	0.957752560758044	0.493249858437103	0.478725507986153	0.494300934775419	0.419121049465765	NA	NA	0.966026684250948	0.498927659806086	77.0537341952846
a5162	BRCA1_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.89111010133013	4.45545067784216	0.435659423487968	1.10580760407583	0.893081415644212	0.474896338105807	0.393973980538927	0.487816021984638	0.419219883484073	NA	NA	0.526256062248501	0.497933787084623	77.056973807044
a5163	loss_cnaOV55	1495	AZD-2281	PARP1, PARP2	8	25	2.30258509299405	NA	3.44161023894135	3.59951670659278	-0.157906467651422	1.01590484020108	0.892702291386266	0.171272130751523	0.155434309792409	0.17688592174017	0.419437939968896	NA	NA	0.14101416889948	0.701551753119112	77.0678081988906
a5164	gain_cnaOV95_(MECOM)	306	TG101348	JAK2	9	23	2.32630161961136	NA	2.50294796856288	2.94971061159723	-0.446762643034346	1.50547586281517	1.34985552080469	0.320707076906275	0.296758423080209	0.330970712160378	0.419548867016435	NA	NA	0.625704335870411	0.451010411086637	77.0678081988906
a5165	loss_cnaOV40	235	QL-XII-47	BTK, BMX	7	25	2.32630161961136	NA	2.17338653051261	1.39502150271847	0.778365027794134	1.19423053476107	1.6868791527754	0.486317993935978	0.651771165732134	0.461423111734768	0.419686140451397	NA	NA	0.0773894781705658	0.189606588499362	77.0678081988906
a5166	gain_cnaOV49	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	2.39648971951826	2.82945027939978	-0.432960559881524	0.614859725666746	1.26462555245913	0.3514245379456	0.704161521413729	0.342362653545637	0.419715488452177	NA	NA	0.0931922444289472	0.365554895307061	77.0678081988906
a5167	loss_cnaOV84	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-4.63642467169876	-3.7489005653205	-0.887524106378263	2.24868025844306	1.63132694380608	0.494226863528813	0.39468666256392	0.544050418432718	0.419722429744922	NA	NA	0.586924457502267	0.45121278775481	77.0678081988906
a5168	gain_cnaOV26	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.81582982045669	1.1030782884422	0.712751532014492	1.11664775042314	1.5123339124662	0.478363105202072	0.638295766721784	0.471292434917493	0.419766171412446	NA	NA	0.812176175395026	0.389263062682462	77.0678081988906
a5169	TP53_mut	222	BX-912	PDPK1 (PDK1)	22	10	2.32630161961136	NA	3.52110335560206	3.16530763277199	0.355795722830075	1.33088352945645	0.908368928642549	0.291732296960022	0.267337986349103	0.39168636399945	0.419910114307551	NA	NA	0.324338255932572	0.386620212343134	77.0697852923834
a5170	loss_cnaOV40	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.60678035767806	5.1518741671108	0.454906190567264	0.826032489807051	0.706413318530661	0.625114503026154	0.550712225221944	0.643966044572132	0.419939392447889	NA	NA	0.123363998005567	0.366301481648286	77.0697852923834
a5171	MLL2_mut	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	3.12963034080494	3.97831069161656	-0.848680350811615	1.14941856918844	1.04686565016786	0.805365242263659	0.738356220755014	0.810686978482422	0.420058246681081	NA	NA	0.314088266546355	0.328104835006442	77.0766896804728
a5172	gain_cnaOV49	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-5.09528400401026	-4.60071330491985	-0.494570699090413	1.26627770663701	1.43614169843488	0.347048376050011	0.390570485840658	0.344374583392014	0.420148054224299	NA	NA	0.133475679851043	0.577556947861554	77.0782626380495
a5173	loss_cnaOV16, loss_cnaOV17	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	0.117526398757426	-0.681542804840106	0.799069203597533	1.20471212221624	1.50874649847781	0.54128995991837	0.663286430726312	0.529624562114126	0.420699493027551	NA	NA	0.908350097868807	0.380544158463594	77.1563313930169
a5174	gain_cnaOV72_(ASXL1)	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.84340507686595	2.13116404901951	0.712241027846442	1.37899131239218	1.37854498277531	0.516630067165078	0.516494209532685	0.516661434153963	0.420768085674095	NA	NA	0.744467566154622	0.405125922866741	77.1563313930169
a5175	SMARCA4_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	0.288000059124429	0.929382228964948	-0.641382169840519	0.419017872400797	1.28038192107077	0.516540191722344	1.53067974443588	0.500930354674282	0.420903588981741	NA	NA	0.844123074080586	0.0991177343446841	77.1563313930169
a5176	loss_cnaOV33_(ZFHX3)	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.84573706182657	3.43158960488781	0.414147456938763	1.33967451517707	0.841426271380463	0.459267286788943	0.309140356293202	0.492196964874063	0.420975305666768	NA	NA	0.793238708415832	0.585603589578496	77.1563313930169
a5177	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1007	Docetaxel	Microtubules	8	23	-4.38202663467388	NA	-4.26686586922725	-4.78134337373776	0.514477504510513	1.52269639711476	1.37767937601015	0.3638336916773	0.337872674740254	0.373437763146657	0.421080438030724	NA	NA	0.133493328798572	0.416704244142214	77.1563313930169
a5178	gain_cnaOV48_(SOX17)	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	3.63203599880285	4.00580808645487	-0.373772087652018	0.941488997960086	1.1870037946038	0.318993154777406	0.397001014841242	0.314887020034149	0.421151446536533	NA	NA	0.0813513937648937	0.574209748104215	77.1563313930169
a5179	PIK3R1_mut	1061	SB590885	BRAF	5	28	1.6094379124341	NA	3.60130193421015	3.98579659033587	-0.384494656125713	0.539990178707033	1.362322905397	0.298959821859892	0.71204009125936	0.282234596953844	0.421295710131343	NA	NA	0.571295485730749	0.292872190494381	77.1563313930169
a5180	loss_cnaOV82	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	2.62057962241283	2.96777822941348	-0.347198607000658	0.229870684416353	0.894409110265834	0.406696102503894	1.51040837539681	0.388187690639091	0.421359158900541	NA	NA	0.326462226749372	0.170254718191265	77.1563313930169
a5181	gain_cnaOV26	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	3.76487215009296	2.46541058916135	1.29946156093161	2.11885095091878	2.3346634665353	0.559895450044399	0.613285970100035	0.5565948067282	0.421362251269791	NA	NA	0.383628022514496	0.402623987031577	77.1563313930169
a5182	ARID1A_mut	282	EKB-569	EGFR	8	24	0.916290731874155	2.99573227355399	1.10665943044675	1.87592450242243	-0.769265071975681	1.36026966909055	1.48426542529439	0.528240639334258	0.565523946799458	0.518279991480029	0.421386775397412	NA	NA	0.324058916102327	0.198943089423521	77.1563313930169
a5183	loss_cnaOV52, loss_cnaOV53	1230	IOX2	EGLN1	8	24	-2.30258509299405	NA	0.126525315289731	-0.126665319675737	0.253190634965468	0.821001816925567	1.0056786106916	0.262169610337848	0.308392295541561	0.251760982359314	0.421614152653004	NA	NA	0.546958929037078	0.48755948517624	77.1589741321597
a5184	loss_cnaOV83	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-4.72758907611953	-3.78375833123351	-0.943830744886017	2.58586108457629	1.57777243914083	0.525155952205929	0.364996693177224	0.598204608897832	0.421658816764195	NA	NA	0.586989002538604	0.528395635070226	77.1589741321597
a5185	gain_cnaOV18_(CCNE1)	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-1.03862547846024	-1.7145766508194	0.675951172359159	0.844143961398836	1.37559031262716	0.520876826033128	0.800753429828529	0.491389889965276	0.421697329493649	NA	NA	0.618783744429528	0.255692938784728	77.1589741321597
a5186	ARID1A_mut	1203	QL-XII-61	BTK	6	17	2.30258509299405	NA	3.57612499932465	4.0028842243236	-0.426759224998944	1.44290510625768	1.52839850248973	0.282906317932846	0.295763888524719	0.279219865960194	0.421726489378323	NA	NA	0.0677811378694858	0.554482089790633	77.1589741321597
a5187	loss_cnaOV85	1033	Vismodegib	SMO	7	24	2.30258509299405	NA	5.2299562944113	4.8178978740965	0.412058420314797	0.975251720533735	0.812755255688078	0.485385061025074	0.4225149380811	0.506989548736844	0.422052205372022	NA	NA	0.152193517162864	0.335887337063645	77.1986977266171
a5188	loss_cnaOV40	1248	FK866	NAMPT	7	25	0	NA	-0.599206910213818	-2.01891998416387	1.41971307395005	3.81907871150755	2.3576129382601	0.523180148581805	0.371742292106262	0.602182423972353	0.42215412709892	NA	NA	0.0435970429297426	0.379607030012932	77.1986977266171
a5189	loss_cnaOV57_(ZNRF3)	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	4.93854818813102	4.38199725641374	0.556550931717274	1.14444873502713	0.95313411022969	0.571432085767762	0.48630481618216	0.583916707779091	0.422219302572164	NA	NA	0.0305315917181413	0.411156776905017	77.1986977266171
a5190	loss_cnaOV87, loss_cnaOV88	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.77046623157115	3.38258074728166	-0.612114515710519	1.27483014442837	1.22343266380318	0.498900863587773	0.480153782357405	0.500325464425389	0.422302379973616	NA	NA	0.993579852163926	0.49787316923076	77.1986977266171
a5191	BRCA1_mut	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.25418879977966	1.85160751792116	0.402581281858506	0.569557499623359	1.44457068477402	0.290823622450214	0.706831675686349	0.278685761868055	0.42241957820448	NA	NA	0.0334753001097575	0.328061879534751	77.1986977266171
a5192	gain_cnaOV96	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-1.08902937090414	-0.413065879836857	-0.675963491067282	1.07544372392225	1.55259737712393	0.456850140364247	0.628543805715819	0.43537590686869	0.42260406948798	NA	NA	0.908365672869867	0.347989631098093	77.1986977266171
a5193	gain_cnaOV50	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.02233865375142	1.35097056871893	-0.328631914967513	1.10211950366214	1.23544817157032	0.26876027317119	0.298181743336843	0.266002186518116	0.422938303594046	NA	NA	0.0959431870123048	0.611085116305175	77.1986977266171
a5194	loss_cnaOV81_(RB1)	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-5.05753560241702	-4.01171486963836	-1.04582073277866	0.938142451895493	2.45307217937429	0.447278343261794	1.11477817752049	0.426331007123249	0.42311296201936	NA	NA	0.9276632763852	0.147506823782988	77.1986977266171
a5195	KRAS_mut	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.1599634439164	2.45893294612133	-0.298969502204932	0.875252052915204	0.957665148896902	0.31745838586753	0.341581035096295	0.312185843401844	0.423196624938967	NA	NA	0.733550924680504	0.45158217839607	77.1986977266171
a5196	loss_cnaOV55	312	AV-951	VEGFR	7	25	-2.05572501506252	NA	0.888062435239555	0.570346836693615	0.317715598545941	0.479361583068323	0.635353454940031	0.523101714112034	0.662789029759727	0.500061180238532	0.423250972604722	NA	NA	0.0146546329992532	0.175466215143132	77.1986977266171
a5197	loss_cnaOV41	1030	KU-55933	ATM	5	28	2.30258509299405	NA	4.54100926123478	4.08134929539783	0.45965996583695	1.31661649400685	0.973444300272316	0.448796311292445	0.349122138397392	0.472199555442836	0.423266596933872	NA	NA	0.52774563801291	0.490953057875909	77.1986977266171
a5198	gain_cnaOV72_(ASXL1)	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	8.11779921874987	8.85228036382919	-0.734481145079329	1.79685059697947	1.69360408994904	0.430888189142766	0.408760275514281	0.433679364284854	0.423299754864957	NA	NA	0.921396612493072	0.4867799511776	77.1986977266171
a5199	PIK3CA_mut	1025	SB 216763	GSK3A, GSK3B	5	18	2.30258509299405	NA	4.59249017482996	5.0620299385631	-0.469539763733136	0.742982367324696	0.824968602301836	0.579684284739638	0.631966227440682	0.569160768571096	0.423530919503502	NA	NA	0.450884524723762	0.262017775352895	77.1986977266171
a5200	loss_cnaOV33_(ZFHX3)	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.16776673565425	3.61100324011589	-0.44323650446164	1.04705757046827	0.94520013886723	0.463697416819962	0.423316269289198	0.468934023848996	0.423566914302922	NA	NA	0.72719514494759	0.47085402000202	77.1986977266171
a5201	PIK3CA_mut	275	I-BET	BRD2, BRD3, BRD4	6	25	2.99573227355399	NA	3.70721228329786	3.97089239004212	-0.263680106744254	1.21925915987577	1.22859898629726	0.214899308274954	0.216262559611297	0.214618528653464	0.423567250977716	NA	NA	0.697303528082656	0.648063918588311	77.1986977266171
a5202	loss_cnaOV35	1028	VX-702	p38	5	26	0.693147180559945	NA	3.07103540386717	3.37618726351279	-0.305151859645619	1.40418064152297	0.824550921959177	0.329423771628876	0.217316668968355	0.370082491595014	0.42357946955748	NA	NA	0.51597567619733	0.659647691825768	77.1986977266171
a5203	gain_cnaOV4_(KRAS)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	5	26	2.30258509299405	NA	4.2144202088284	4.5688272178045	-0.354407008976092	0.570118206353431	0.964162951932917	0.385265868225682	0.621637767442891	0.367579990773956	0.423610718699311	NA	NA	0.526347310179218	0.292622299065384	77.1986977266171
a5204	gain_cnaOV50	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	3.67519154732988	4.14242657612163	-0.467235028791757	1.0586694610722	1.12461946569174	0.417845852472135	0.441341746382813	0.415460556255236	0.423685114454921	NA	NA	0.818766010386306	0.45835332504338	77.1986977266171
a5205	gain_cnaOV51_(MYC)	293	MP470	PDGFR	8	24	2.99573227355399	NA	3.55702987190216	4.21331367942215	-0.656283807519994	2.04811587308734	1.65836445228534	0.373513216328336	0.320432948225097	0.395741603491072	0.42375606695648	NA	NA	0.62051514371379	0.430316346953659	77.1986977266171
a5206	gain_cnaOV72_(ASXL1)	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.89187939856898	5.6958437918454	0.196035606723576	0.598577496515704	0.605911382281988	0.324058647768248	0.32750246687303	0.323538412474221	0.423764287135047	NA	NA	0.190245129703515	0.52853791596569	77.1986977266171
a5207	loss_cnaOV16, loss_cnaOV17	326	GSK690693	AKT	6	26	2.32630161961136	NA	4.72927267270915	4.01869848933594	0.710574183373213	0.970582684790939	1.51859870473169	0.492837901683896	0.732110921107426	0.467914387888772	0.423791903468558	NA	NA	0.0920434568191973	0.178309508079759	77.1986977266171
a5208	loss_cnaOV84	208	SB-715992	KIF11	6	26	-2.05572501506252	NA	-0.566725082379075	-1.49063151027626	0.923906427897183	2.13185108095465	1.78853612679665	0.499359075212844	0.433382254581992	0.516571297641017	0.42385396424741	NA	NA	0.0728004379926329	0.358925615004867	77.1986977266171
a5209	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.55107055937719	3.0195351657689	0.531535393608298	1.21829734851765	0.887702733585288	0.582407287729075	0.436293647240585	0.598776339756792	0.423982566850817	NA	NA	0.236717290526112	0.531527785324324	77.1986977266171
a5210	gain_cnaOV26	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.24024663943461	4.47383279005952	-0.233586150624904	0.67681263813082	0.547027130343682	0.419649686984724	0.345126756601366	0.427010174939857	0.424080116440074	NA	NA	0.362553777274347	0.614986120330913	77.1986977266171
a5211	loss_cnaOV39	253	XMD14-99	EPHB3, CAMK1	9	23	2.32630161961136	NA	5.0720143302174	4.77712675270331	0.294887577514093	0.731665660483754	0.559734737213214	0.483155227138394	0.403035967711157	0.526834512687684	0.424094062977997	NA	NA	0.0486241042181221	0.297091856561532	77.1986977266171
a5212	gain_cnaOV72_(ASXL1)	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.21561727628509	4.88802836559161	0.32758891069348	0.803953857249596	0.818440320941438	0.40116912964715	0.407472279334779	0.400259985134481	0.424168919838457	NA	NA	0.945723507970038	0.436922510978861	77.1986977266171
a5213	loss_cnaOV82	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	1.72677792378752	2.33989468035606	-0.613116756568543	1.53649341723127	1.81254388590755	0.34137618488595	0.399036370538682	0.338263123632758	0.424255516787099	NA	NA	0.108949291353806	0.569993205522404	77.1986977266171
a5214	loss_cnaOV59	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.37283013893156	2.92877007992136	-0.555939940989803	0.356750130878469	1.16769977485166	0.499269429862827	1.55834544368868	0.476098354185629	0.424270411281821	NA	NA	0.38850208340677	0.0686344240372086	77.1986977266171
a5215	loss_cnaOV33_(ZFHX3)	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.39656277144952	2.07651896606318	0.32004380538634	0.641381732421946	0.542928508094314	0.578508276147574	0.498991145534829	0.589476884368621	0.424303105483204	NA	NA	0.0414285892240837	0.400238687974439	77.1986977266171
a5216	loss_cnaOV84	1043	JNK Inhibitor VIII	JNK	6	27	2.30258509299405	NA	4.80520956604745	4.36133095724502	0.443878608802437	0.987471718401044	1.00524624640882	0.442815539236497	0.449510199159105	0.441562065402548	0.424566503479015	NA	NA	0.372725494142514	0.35183864143719	77.2102935526924
a5217	gain_cnaOV51_(MYC)	253	XMD14-99	EPHB3, CAMK1	8	24	2.32630161961136	NA	5.08341420796801	4.78561377584953	0.297800432118483	0.576568008930887	0.621314570581366	0.487265389214967	0.51650529947141	0.479307014866607	0.42461097949933	NA	NA	0.0486293635543362	0.23694009150953	77.2102935526924
a5218	gain_cnaOV96	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	3.00931717834117	2.29218902076203	0.717128157579134	1.39171986014577	1.28457999830996	0.553623390347762	0.51528197456636	0.558258853884236	0.424654291141681	NA	NA	0.10845007681142	0.38836239793549	77.2102935526924
a5219	loss_cnaOV59	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.30400745219301	3.93353643050126	0.370471021691744	1.28664636621454	0.673284750936603	0.489189702165778	0.287935388790403	0.550244188920636	0.424804193913335	NA	NA	0.523589850456418	0.608906473429775	77.2102935526924
a5220	PTEN_mut	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	3.57060316103662	4.40958540858739	-0.838982247550775	1.58323550513178	1.25457152825878	0.65035242829274	0.529916266298578	0.668740066750277	0.424829192938901	NA	NA	0.368888647238973	0.37366991423917	77.2102935526924
a5221	loss_cnaOV55	308	XL-880	MET	7	25	1.63315443905142	NA	-0.0637892274156674	0.341826936583175	-0.405616163998843	0.66447158142926	1.02497272024337	0.420885107061418	0.610434178578975	0.395733619039668	0.424855084650798	NA	NA	0.366010331012955	0.230039589228147	77.2102935526924
a5222	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.82223912633282	3.1684022221206	0.653836904212215	0.39721400862708	1.26400164842304	0.533552372526198	1.64605701211828	0.517275357218036	0.425041629434778	NA	NA	0.599177122142691	0.0824959930362802	77.2175803424024
a5223	gain_cnaOV48_(SOX17)	309	Y-39983	ROCK	3	29	2.99573227355399	NA	4.49333375921351	5.01300916554941	-0.519675406335894	1.42213566091322	1.22341070943726	0.419888098472203	0.365419010730796	0.42477591730003	0.425102182866163	NA	NA	0.370320093952895	0.596357654148287	77.2175803424024
a5224	gain_cnaOV94	224	AS605240	PI3Kgamma	7	25	2.99573227355399	2.32630161961136	3.76627640574365	3.26557197795641	0.50070442778723	1.65776661907716	1.67171726691592	0.300014073543645	0.302035535053759	0.299515018296699	0.425139326586358	NA	NA	0.628120831160005	0.497366849626912	77.2175803424024
a5225	loss_cnaOV57_(ZNRF3)	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.68231591337458	4.16684288391872	0.515473029455858	1.39307185382598	0.914188931694559	0.53091692860109	0.370026160560307	0.563858313729928	0.425314104961465	NA	NA	0.207526384141623	0.518856255792645	77.2345405833363
a5226	loss_cnaOV59	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.39596476614199	2.07660144955387	0.31936331658812	0.600308930858001	0.54798744886901	0.577231706053684	0.53199827650684	0.582793122811943	0.42571649503787	NA	NA	0.0414410857633635	0.374529695996788	77.2587751912393
a5227	loss_cnaOV16, loss_cnaOV17	263	FR-180204	ERK	6	26	2.99573227355399	NA	5.01758811262596	4.76426764950376	0.253320463122197	0.635592064063024	0.766713788968668	0.339361786162636	0.398558253705758	0.330397687855525	0.425881545446041	NA	NA	0.764119631967459	0.420842639937107	77.2587751912393
a5228	loss_cnaOV54	1067	CCT007093	PPM1D	11	22	1.88706964903238	NA	4.70755520373798	4.38081439792056	0.326740805817417	0.297534520344645	0.809953471893139	0.475106309901036	1.09816099805475	0.403406883427158	0.425922219036828	NA	NA	0.080127366837199	0.103745116129614	77.2587751912393
a5229	ARID1A_mut	158	PF-562271	FAK	5	13	0.940007258491471	NA	2.02799081083241	2.38999714919807	-0.36200633836566	1.42425514501584	1.39644960027726	0.257939833349787	0.254172392939913	0.259233371754903	0.425962499593626	NA	NA	0.744589129126626	0.641712125422471	77.2587751912393
a5230	loss_cnaOV44	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.17998113366185	4.43285725367946	-0.252876120017611	0.617580586065589	0.633715540079933	0.399707657101457	0.409462547436286	0.399037271495211	0.426042072582071	NA	NA	0.268902812390321	0.558475582729006	77.2587751912393
a5231	loss_cnaOV58	219	AT-7519	CDK9	5	27	2.32630161961136	NA	2.17001682598794	1.37320601718564	0.7968108088023	1.51041762427593	1.71889737123669	0.470765777379201	0.527543373432416	0.463559268945198	0.426048850951528	NA	NA	0.313848812383532	0.329584218316706	77.2587751912393
a5232	loss_cnaOV57_(ZNRF3)	1028	VX-702	p38	4	27	0.693147180559945	NA	3.72153703628582	3.26851473057501	0.45302230571081	0.815097934437854	0.931631035791717	0.492276183287265	0.555788803492974	0.486267941176759	0.426110958115782	NA	NA	0.516028390929393	0.363244286239403	77.2587751912393
a5233	loss_cnaOV82	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.29971311611448	2.9171635670752	-0.617450450960718	0.594185460944959	1.14230415849591	0.554172939747389	1.03915442491433	0.54053068647997	0.426168246165953	NA	NA	0.388544901538318	0.204566792773146	77.2587751912393
a5234	loss_cnaOV35	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	-0.145463316809403	-0.648862480173672	0.503399163364269	2.93871166951049	1.68882479743008	0.267834189495459	0.171299269876354	0.298076605773614	0.426242797990931	NA	NA	0.0410551732981623	0.79775897702797	77.2587751912393
a5235	loss_cnaOV83	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.25113147898593	4.43841282825038	-0.187281349264453	0.926020449028932	0.575236113542998	0.29570698320033	0.202243211217252	0.32557300359838	0.426261813469582	NA	NA	0.268907757848343	0.681978777933891	77.2587751912393
a5236	loss_cnaOV81_(RB1)	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.23714092935748	2.57482977399179	0.662311155365687	0.612345917071182	1.77997499390297	0.389057527186682	1.08159642597682	0.372090146004485	0.426430676477194	NA	NA	0.63850682929029	0.166709457344446	77.2668338354469
a5237	loss_cnaOV57_(ZNRF3)	1262	UNC1215	LMBL3	4	29	0	NA	3.01831962099999	2.74759795744153	0.270721663558454	0.67924225774825	0.465649169145099	0.552039976812294	0.398564224281218	0.58138547536868	0.426469143360158	NA	NA	0.108152294309985	0.489983826342492	77.2668338354469
a5238	loss_cnaOV16, loss_cnaOV17	1016	Temsirolimus	MTOR	6	25	-1.6094379124341	NA	-1.35322167644066	-2.19163065439921	0.838408977958551	1.10022603693953	1.61221363115489	0.545781389496578	0.762033391148177	0.520035907001957	0.42663100366442	NA	NA	0.0369764895489957	0.157939508503594	77.2814025566327
a5239	NF1_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.93554567643108	3.42354644661836	0.511999229812722	1.27880095969826	1.08803608987841	0.461554653933295	0.400374449150814	0.470571918133653	0.427072772050091	NA	NA	0.72551472374619	0.492576901374263	77.335449700014
a5240	gain_cnaOV95_(MECOM)	185	OSI-906	IGF1R	5	13	0.940007258491471	NA	1.83823976800606	2.35035003333384	-0.512110265327783	2.08033931343882	0.905607560746483	0.39311225599275	0.246166700797122	0.565488062959253	0.427092382594452	NA	NA	0.683107901301896	0.619788257341844	77.335449700014
a5241	NF1_mut	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	2.50652848803753	2.90576754806378	-0.399239060026249	1.42685012291778	1.02574865886498	0.372205870738375	0.279804482344537	0.389217238137088	0.427320099478483	NA	NA	0.304576062266696	0.62205324224176	77.3390207953683
a5242	loss_cnaOV38	1025	SB 216763	GSK3A, GSK3B	7	16	2.30258509299405	NA	5.21641165303417	4.84775676231539	0.368654890718778	1.06927653417171	0.688893591788487	0.451851570256919	0.344770392819243	0.53514054291271	0.427405946259911	NA	NA	0.451006144303156	0.424976333578022	77.3390207953683
a5243	gain_cnaOV96	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	0.464002470474311	1.10421020709988	-0.640207736625566	0.571694948974204	1.64273950844793	0.414779556286061	1.11984151298572	0.389719571078217	0.427432303145803	NA	NA	0.790044959888963	0.13201757261482	77.3390207953683
a5244	NF1_mut	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	2.79015307090634	3.73486163788834	-0.944708566981995	2.4795541628191	1.98754370875485	0.466737412751623	0.380999367203949	0.475314612111767	0.427568369730959	NA	NA	0.746260081154098	0.58122593518387	77.3390207953683
a5245	loss_cnaOV55	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	2.32300882034821	1.73746127156075	0.585547548787458	0.712446254129216	1.80933136568994	0.350838387283623	0.821883118050975	0.323626484286462	0.427571574582544	NA	NA	0.341796869586518	0.336335099298242	77.3390207953683
a5246	gain_cnaOV51_(MYC)	230	GSK429286A	ROCK2	8	24	2.99573227355399	2.32630161961136	5.84204923156605	5.43764465450675	0.404404577059307	0.683565650298787	1.04391936534295	0.416113042192508	0.591610442804641	0.387390626599262	0.427601163969904	NA	NA	0.301957602892016	0.224910434817162	77.3390207953683
a5247	BRCA1_mut	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-4.22328472226512	-4.71158095039726	0.488296228132137	0.799398164748315	1.47816809232034	0.343134891018881	0.61082980880482	0.330338769094684	0.427716701310242	NA	NA	0.133617306699161	0.354597510371996	77.3451740620465
a5248	gain_cnaOV19	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.75349432786856	2.33253616033995	0.42095816752861	1.21256852383615	0.950990784843382	0.427205916311512	0.347162374128635	0.44265220466667	0.42794926315559	NA	NA	0.406150339032655	0.61645446290091	77.3603820436855
a5249	gain_cnaOV50	293	MP470	PDGFR	4	28	2.99573227355399	NA	3.32560637433974	4.15261934942821	-0.827012975088474	3.02943356052641	1.55486622526637	0.470197813474199	0.272992610191051	0.531886899110434	0.428057169827551	NA	NA	0.620587075843522	0.626698941106924	77.3603820436855
a5250	gain_cnaOV18_(CCNE1)	290	KIN001-260	IKK	4	27	2.99573227355399	NA	5.21634393580014	4.79600975236617	0.420334183433975	0.707718107905552	0.917199449295844	0.468183228934414	0.593928823833444	0.458280021599092	0.428176285913245	NA	NA	0.663841106794239	0.339907433982362	77.3603820436855
a5251	PIK3CA_mut	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	5.696101957275	5.85774369980424	-0.161641742529244	1.46726571961102	1.24871141185309	0.124783688344646	0.110165282517536	0.129446836951195	0.428246284636931	NA	NA	0.569170257065321	0.796686985948266	77.3603820436855
a5252	loss_cnaOV52, loss_cnaOV53	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-4.62616700298649	-3.75256401843202	-0.873602984554465	1.40264342940057	1.90228407889484	0.486074480335743	0.622826134028807	0.459238971847988	0.428260689204294	NA	NA	0.587205709723726	0.305456780919403	77.3603820436855
a5253	loss_cnaOV59	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-3.28582085633536	-4.28428636903554	0.998465512700183	2.06065511772035	2.37213922808047	0.426558063412993	0.484537904530457	0.420913536979926	0.428289995774614	NA	NA	0.927682589002706	0.423473045768744	77.3603820436855
a5254	loss_cnaOV35	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.31546630290502	4.5448388915239	-0.229372588618884	0.39386997058088	0.617597712464953	0.382927673714012	0.582356121947061	0.371394815734361	0.428515708115078	NA	NA	0.613412150138573	0.359096503795745	77.3648254059461
a5255	gain_cnaOV18_(CCNE1)	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	0.847632377525548	1.48464888858385	-0.637016511058303	1.73550048161937	1.38515786294449	0.435728219860314	0.367050610359908	0.4598873010071	0.428557046806861	NA	NA	0.855111632878829	0.536780108130286	77.3648254059461
a5256	loss_cnaOV54	1378	Bleomycin (50 uM)	DNA damage	11	21	3.91202300542815	NA	2.60903457152491	1.74483400148012	0.864200570044792	1.7254915390356	2.06558646629855	0.441190237331703	0.500843122376481	0.418380244131539	0.428559206964094	NA	NA	0.130717230658293	0.221446644963498	77.3648254059461
a5257	loss_cnaOV36	333	T0901317	LXR	3	29	2.32630161961136	NA	5.38897135786325	4.68759799901742	0.701373358845838	1.41717387592152	1.08352165871878	0.632498764062914	0.494909884215702	0.647309034574521	0.428684414730857	NA	NA	0.00493423112746376	0.484246681736392	77.3727074621301
a5258	gain_cnaOV49	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.81775311714669	3.16886629203641	0.648886825110283	0.557472146672039	1.25991984329179	0.529409943061888	1.16398071003899	0.515022307621519	0.428881340413326	NA	NA	0.599243952262296	0.169189756623686	77.3935283342076
a5259	loss_cnaOV16, loss_cnaOV17	282	EKB-569	EGFR	6	26	0.916290731874155	2.99573227355399	2.21255202743638	1.56154428219593	0.651007745240453	1.26161601239042	1.5119325682992	0.441909512896245	0.516011004019338	0.430579880935289	0.428977015586995	NA	NA	0.324232912868104	0.30282255432011	77.3960736617392
a5260	KRAS_mut	173	FH535	unknown 	3	15	3.46573590279973	NA	3.42630616992115	2.31093043145027	1.11537573847088	2.3888199768782	1.18345939511519	0.801038470551568	0.46691494096114	0.942470644176441	0.429193343865417	NA	NA	0.118030730340433	0.505906162859037	77.4203821275693
a5261	loss_cnaOV44	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.1385125401348	-2.12480567136499	0.986293131230194	0.324927299046273	1.59847480993798	0.638489429465207	3.03542710669483	0.61702137881576	0.429520254075038	NA	NA	0.0370014606549697	0.0128869622637824	77.4511079882904
a5262	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	8	25	-2.30258509299405	NA	0.0159854608101114	-0.44410332910409	0.460088789914202	1.50298045144003	1.37385192401581	0.327687269064218	0.30611761415352	0.334889649948118	0.429650721949964	NA	NA	0.888481486358163	0.458012262043767	77.4511079882904
a5263	loss_cnaOV55	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	-0.391610023383579	0.266731884562559	-0.658341907946139	1.22019299320887	1.69945496776256	0.408393005522319	0.53953916438647	0.387384143995818	0.429756163167222	NA	NA	0.459761898809751	0.273681434200704	77.4511079882904
a5264	PIK3R1_mut	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.60465959824665	3.37385378369378	0.230805814552874	0.99824111169794	1.26006880194945	0.187893381664566	0.231212491499463	0.183169215995027	0.42981525086013	NA	NA	0.324565581861121	0.664126394845455	77.4511079882904
a5265	loss_cnaOV40	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	-1.38629436111989	0.693147180559945	-1.86141675025922	-2.20746676133798	0.346050011078761	1.32444351800991	1.28600972248499	0.267263829195056	0.261279553543159	0.269088176417578	0.429821732307597	NA	NA	0.605957067417364	0.529818854117948	77.4511079882904
a5266	loss_cnaOV81_(RB1)	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.47617822404545	3.64722083111827	0.828957392927176	0.796799573594103	1.60799303938283	0.535440172011947	1.04035873060024	0.51552299831182	0.429965034608082	NA	NA	0.163369743313377	0.139389648738159	77.4511079882904
a5267	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.30380208850007	2.91674056993186	-0.612938481431794	0.402885533798965	1.14848686836963	0.550011925541176	1.52137128293527	0.533692198241596	0.430050502479683	NA	NA	0.388631600537848	0.0967537655741234	77.4511079882904
a5268	loss_cnaOV85	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	3.97682836981603	3.59874639757801	0.378081972238022	0.791416576051988	1.10442399648167	0.360311827586544	0.477728144290455	0.342334079522416	0.430098384027681	NA	NA	0.830220331590424	0.327351380470053	77.4511079882904
a5269	loss_cnaOV83	1006	Cytarabine	DNA synthesis	5	26	0.693147180559945	NA	0.329526872224181	-0.196085486546828	0.525612358771009	1.04129767058661	1.28539197955705	0.418964664429711	0.504766671066217	0.408912119517142	0.430159103734044	NA	NA	0.766062096600224	0.355909657485186	77.4511079882904
a5270	loss_cnaOV57_(ZNRF3)	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	4.95648945919397	5.22427219438871	-0.267782735194736	0.301397790714653	0.807864843890041	0.34672890770981	0.888469469400516	0.331469721971444	0.430179958771112	NA	NA	0.331434459076085	0.237778809005926	77.4511079882904
a5271	gain_cnaOV96	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.9366939692928	4.53868622493478	0.398007744358022	0.534151055236406	0.977396709445666	0.422289531339347	0.745122078214131	0.407212077257507	0.4303870321515	NA	NA	0.942881648177509	0.263545015102584	77.4654044170926
a5272	loss_cnaOV87, loss_cnaOV88	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.48070302653888	4.88984035633823	-0.409137329799352	1.43622861797127	0.847909548271378	0.454141268964799	0.284869222545695	0.482524734664746	0.430422650469498	NA	NA	0.663875870700873	0.672927414045249	77.4654044170926
a5273	loss_cnaOV38	211	TL-2-105	CRAF	8	24	2.32630161961136	1.63315443905142	4.30650780504218	4.44336422155636	-0.136856416514176	0.696458882532568	0.614094368676693	0.215769918082184	0.196503225023878	0.222858934220626	0.430689746461975	NA	NA	0.269006603008294	0.630237627920792	77.48929062247
a5274	gain_cnaOV18_(CCNE1)	1028	VX-702	p38	3	28	0.693147180559945	NA	3.77994319051976	3.27843629639676	0.501506894123	0.541301093368262	0.94294592788629	0.544590797671581	0.926484169840409	0.531851169077297	0.430874382615775	NA	NA	0.516126305284294	0.245600877311119	77.48929062247
a5275	gain_cnaOV19	1028	VX-702	p38	3	28	0.693147180559945	NA	3.77994319051976	3.27843629639676	0.501506894123	0.541301093368262	0.94294592788629	0.544590797671581	0.926484169840409	0.531851169077297	0.430874382615775	NA	NA	0.516126305284294	0.245600877311119	77.48929062247
a5276	loss_cnaOV36	308	XL-880	MET	3	29	1.63315443905142	NA	-0.229824980774338	0.303055991896301	-0.532880972670639	0.613048627606102	0.986314508565607	0.5516776687213	0.86923116482862	0.540274900189399	0.430882043163188	NA	NA	0.366146276315524	0.268334991340982	77.48929062247
a5277	SMARCA4_mut	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	2.8898490856606	3.83348565805433	-0.943636572393733	1.40567878768975	1.55738259829749	0.609567043938631	0.67130313173795	0.605911850707272	0.430979101811787	NA	NA	0.163388624927863	0.36622672324807	77.4920578759696
a5278	loss_cnaOV58	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.71913042634997	3.19416506315546	0.524965363194511	0.791118265348257	1.06338177433664	0.509061499858423	0.663573812144783	0.493675343948786	0.431268460441213	NA	NA	0.0905349946962635	0.239849825114762	77.5088496068849
a5279	loss_cnaOV55	303	PIK-93	PI4K, PI3K	7	25	2.99573227355399	NA	2.4815236013821	3.02398674331429	-0.542463141932192	1.46160433007572	1.17349882837839	0.43870787831326	0.371142265228573	0.462261340884168	0.431311360138104	NA	NA	0.229544404706273	0.391611907568103	77.5088496068849
a5280	loss_cnaOV38	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	-1.38629436111989	0.693147180559945	-1.86246886164529	-2.20713008569444	0.344661224049142	1.36099341081545	1.27492566400734	0.266176343906109	0.253242389941208	0.270338290128857	0.431394165216828	NA	NA	0.605982827078148	0.539474206130654	77.5088496068849
a5281	gain_cnaOV72_(ASXL1)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.25876796067434	5.12089675054244	0.137871210131903	0.407269031700767	0.612572609890461	0.233939486909339	0.338526132360588	0.225069172055467	0.431428041048947	NA	NA	0.0115470280950171	0.543216570825862	77.5088496068849
a5282	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.5752991248969	3.6649406541307	0.910358470766204	2.11856753799855	1.50265570404645	0.58740531350133	0.42970472002334	0.605833038343203	0.431480935201424	NA	NA	0.16339794435043	0.536981970792686	77.5088496068849
a5283	loss_cnaOV20	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.621742854904646	-0.273261871735377	0.895004726640023	1.73586221370101	1.57476653345775	0.562122642779357	0.51559664100977	0.568341216062577	0.431819530313063	NA	NA	0.0990672892175569	0.388527786747995	77.5309275976263
a5284	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.35029848203273	3.94152256609342	0.408775915939308	1.57172871414818	0.662549772725444	0.539361008525945	0.260080452981257	0.616973898063205	0.43196797131756	NA	NA	0.523730566304586	0.697610979996963	77.5309275976263
a5285	gain_cnaOV49	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-2.0241493591419	-0.959618445609379	-1.06453091353252	0.837781983659501	2.0201278656268	0.542137716878436	1.2706538625748	0.526962145142342	0.432000578137044	NA	NA	0.441560932715135	0.142505098609701	77.5309275976263
a5286	gain_cnaOV95_(MECOM)	345	KIN001-270	CDK9	9	23	2.99573227355399	NA	5.3697443743684	5.12077738740627	0.248966986962133	0.5442298846041	0.835966448279391	0.32372558759933	0.457466585362624	0.29781935324625	0.432055972063735	NA	NA	0.331476566757508	0.332850770927963	77.5309275976263
a5287	loss_cnaOV40	151	QS11	ARFGAP	4	15	2.32630161961136	NA	4.45064938840756	3.58441416643085	0.866235221976712	1.81963897064114	1.33245188599972	0.605532927438647	0.476047851223751	0.650106192259832	0.432088186366341	NA	NA	0.0626563203194288	0.424669231801843	77.5309275976263
a5288	gain_cnaOV48_(SOX17)	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.00784915549915	4.4364635055496	-0.428614350050455	1.21961309957873	0.827469065364609	0.49943810553617	0.351434688753756	0.517982324646292	0.432094113490729	NA	NA	0.868960054692961	0.607508853897262	77.5309275976263
a5289	gain_cnaOV18_(CCNE1)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	1.16877117011865	0.501092045530254	0.667679124588401	0.82574098762696	1.22900845373713	0.553844399498302	0.808581788470012	0.543266502812199	0.432612838919092	NA	NA	0.428810482284905	0.295771964218405	77.5611488126973
a5290	gain_cnaOV19	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	1.16877117011865	0.501092045530254	0.667679124588401	0.82574098762696	1.22900845373713	0.553844399498302	0.808581788470012	0.543266502812199	0.432612838919092	NA	NA	0.428810482284905	0.295771964218405	77.5611488126973
a5291	loss_cnaOV70	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.74028756041057	-2.06190467847638	-0.678382881934187	0.550867371258465	1.32397663964878	0.526622310168733	1.23148132804528	0.51238281826041	0.432618623290614	NA	NA	0.606002786920009	0.151841018050042	77.5611488126973
a5292	gain_cnaOV48_(SOX17)	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	-0.169841778741631	0.968606608033577	-1.13844838677521	0.811507487268672	2.13043727881283	0.551476198787522	1.40288094026949	0.534373106449584	0.432621664526903	NA	NA	0.413753319169042	0.11749290126832	77.5611488126973
a5293	loss_cnaOV21, loss_cnaOV22	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.18395351848283	4.43244631731867	-0.248492798835847	1.31463653408302	0.552814836560965	0.392681491022456	0.189020153018321	0.449504576218882	0.432794330766448	NA	NA	0.269053048463264	0.775422470131704	77.5611488126973
a5294	gain_cnaOV26	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.43536238958575	0.810689574089639	0.62467281549611	0.724392868354497	1.2714131218156	0.502770740815191	0.862339819710115	0.491321667817985	0.432852988758519	NA	NA	0.844211072602415	0.273375963963089	77.5611488126973
a5295	gain_cnaOV94	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	3.4228646580081	3.75385623688422	-0.330991578876124	0.92600747004494	1.08146820521562	0.314566440779522	0.357439426336443	0.306057614343024	0.432884916120861	NA	NA	0.830242268693796	0.438081687140803	77.5611488126973
a5296	loss_cnaOV40	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	2.09990051203612	1.43254125728382	0.667359254752299	1.66774229952389	1.1143774800223	0.538634438978233	0.400157299447772	0.598862833031176	0.43296170467496	NA	NA	0.16128551873963	0.436931950925912	77.5611488126973
a5297	gain_cnaOV4_(KRAS)	330	XMD13-2	RIPK	8	24	2.32630161961136	NA	3.8076283390946	4.17615348366535	-0.368525144570752	1.24501892612761	1.0756153942991	0.329793439457145	0.295999632485088	0.342617952963468	0.433084288179227	NA	NA	0.818845675318101	0.46987278057388	77.5611488126973
a5298	loss_cnaOV59	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	3.01350363396382	2.8423764280213	0.171127205942525	0.895053426386115	0.79753732946435	0.211838592670391	0.19119216897864	0.214569524986948	0.433139022589817	NA	NA	0.0189999746021082	0.736735195055	77.5611488126973
a5299	loss_cnaOV40	205	BMS-708163	g-secretase	7	25	2.32630161961136	0.940007258491471	5.28417018916114	4.99979821479679	0.284371974364355	0.669437148123325	0.595124135346641	0.465641148708047	0.424792641342884	0.477836399961694	0.433231844843501	NA	NA	0.109069686818281	0.336179034092553	77.5611488126973
a5300	loss_cnaOV36	152	CP466722	ATM	3	29	2.77258872223978	NA	2.32391672778627	2.68033047369188	-0.356413745905604	1.04565353740881	0.794392003154128	0.438091213628618	0.340852618151914	0.448662303359633	0.433258488618358	NA	NA	0.554176847986124	0.618564889600126	77.5611488126973
a5301	SMAD4_mut	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	6.44664526586878	5.75780587580775	0.688839390061024	0.547325915731606	1.31737898757734	0.537932674711846	1.2585543097119	0.522886273848803	0.43332521454193	NA	NA	0.569262412878547	0.145509130471078	77.5611488126973
a5302	BRCA1_mut	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	0.406981786651362	-0.112024500339791	0.519006286991153	0.311990632002411	0.989911239952794	0.540782612144842	1.66353163766514	0.524295781322681	0.433412247890666	NA	NA	0.547183505318039	0.0796826907950168	77.5620953688102
a5303	loss_cnaOV52, loss_cnaOV53	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	4.38967822173781	3.79749091163304	0.592187310104771	0.764696527368323	1.71949367197538	0.382369601871133	0.774408263815141	0.344396330010599	0.433511627332947	NA	NA	0.741041258505334	0.316883120805171	77.5652505694441
a5304	gain_cnaOV96	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-1.41239117289318	-2.06944575047417	0.657054577580989	1.36089776927119	2.09741074264828	0.322432892131123	0.482809651405971	0.313269386973466	0.433945768293315	NA	NA	0.276314232385038	0.43863085627456	77.6176837158765
a5305	loss_cnaOV34	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	4.88776685678295	4.37078820919238	0.516978647590573	1.02095042898979	0.965661663055479	0.531207030991042	0.506369979296755	0.535362091474964	0.434058598764377	NA	NA	0.0306183104576068	0.3388567657392	77.6176837158765
a5306	gain_cnaOV19	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.46937671805487	5.10861799702941	0.360758721025461	0.209887887270476	0.599347767284484	0.620334160979314	1.71881629624754	0.601918853656503	0.43409598917716	NA	NA	0.0115563439953625	0.0675723667009997	77.6176837158765
a5307	loss_cnaOV52, loss_cnaOV53	310	YM201636	FYV1	8	24	1.63315443905142	NA	2.12208798396805	2.43519276744477	-0.313104783476719	0.798056374158063	0.882505722163727	0.362582886682998	0.392334167880107	0.354790655304816	0.434131890350641	NA	NA	0.64913462562486	0.366417968523656	77.6176837158765
a5308	loss_cnaOV1	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.75845109104222	4.32610834381568	0.432342747226548	1.36244381586386	1.03860001167417	0.40661894277678	0.317328863174017	0.416274544932494	0.434340486583531	NA	NA	0.349741277632223	0.641616917870346	77.6403484726669
a5309	loss_cnaOV81_(RB1)	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	2.95431453891798	1.91155843436374	1.04275610455424	2.00092683872932	1.96902508344816	0.528717046661126	0.521136547509373	0.529579898864551	0.434779125020521	NA	NA	0.130825617086186	0.38553667317958	77.6975994635163
a5310	loss_cnaOV85	341	EX-527	SIRT1	7	24	2.99573227355399	NA	5.97705418781803	5.71388880545242	0.26316538236561	0.529668558075782	0.565023229901156	0.471713576221612	0.496849167943169	0.465760288141866	0.434824539373292	NA	NA	0.109129833951121	0.280373439843544	77.6975994635163
a5311	loss_cnaOV57_(ZNRF3)	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-3.29881536462734	-4.28228721391369	0.983471849286355	2.07662255773261	2.37133671115346	0.420011572343037	0.473592009113187	0.414733110089616	0.435214051977204	NA	NA	0.927707866702323	0.432876597533615	77.7525577317787
a5312	gain_cnaOV48_(SOX17)	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.41663141549855	-4.12868094872584	0.712049533227284	1.88230021792556	1.49185608910381	0.467837345994086	0.378286910050947	0.477291032578772	0.435641649617607	NA	NA	0.86348241068719	0.583776077413336	77.8142980559687
a5313	loss_cnaOV87, loss_cnaOV88	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.96079489506944	4.24260016026575	0.718194734803686	1.88049656723408	1.25375997840441	0.551049618458126	0.381917599488119	0.57283271692696	0.435774223570386	NA	NA	0.369125019356453	0.578949386238056	77.8233279354451
a5314	loss_cnaOV83	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	2.73665281306758	2.02034964858738	0.716303164480201	1.67036066933171	1.29782217025888	0.530585812238263	0.428831436007641	0.551927052022325	0.43597924104213	NA	NA	0.891326786616351	0.542406929359012	77.8382597385442
a5315	gain_cnaOV50	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	4.96009686829573	5.22375685023132	-0.263659981935583	0.931127926995642	0.75278800622291	0.341317579271704	0.283161931128307	0.350244663512227	0.436100733790326	NA	NA	0.331566414367079	0.619992712923083	77.8382597385442
a5316	RB1_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.86724929869712	1.15094037988126	0.716308918815859	0.755960273832598	1.25671464084996	0.582094029298375	0.947548361482393	0.569985337587375	0.436188395994873	NA	NA	0.265007458649046	0.235736657297077	77.8382597385442
a5317	loss_cnaOV54	1025	SB 216763	GSK3A, GSK3B	8	15	2.30258509299405	NA	5.19220590618459	4.83608950125392	0.356116404930663	0.691906343508197	0.871276987970212	0.436481237188602	0.514688741145274	0.408729267325535	0.436256387576902	NA	NA	0.451277726840676	0.298428914523071	77.8382597385442
a5318	loss_cnaOV38	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	1.60714372552605	2.32828787311947	-0.721144147593419	0.915776722839671	1.33957269201295	0.55720807348274	0.7874672172899	0.538338943375868	0.436400809548117	NA	NA	0.68336435648204	0.317779416826364	77.8382597385442
a5319	SMARCA4_mut	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.2502459977135	1.65215301305108	-0.401907015337576	0.427108150599448	0.693118883276711	0.592227149931379	0.940995892430283	0.579852930045082	0.436438526270398	NA	NA	0.207166022362838	0.238248889687771	77.8382597385442
a5320	loss_cnaOV35	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	5	26	2.30258509299405	NA	1.96146417317237	1.3027866581764	0.65867751499597	2.31506024218598	1.26824212510063	0.451761204032317	0.284518520509004	0.519362590123481	0.43649717895165	NA	NA	0.474505902448165	0.566305088954742	77.8382597385442
a5321	loss_cnaOV70	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	-0.0224993568249093	0.425650609824965	-0.448149966649874	0.794332497489561	0.916570588078211	0.493194149154153	0.564184353612907	0.488942120202131	0.436514123534553	NA	NA	0.909254031607639	0.437115277774879	77.8382597385442
a5322	loss_cnaOV1	1061	SB590885	BRAF	3	30	1.6094379124341	NA	3.31631189290805	3.98866261739103	-0.672350724482986	2.37957809612311	1.16479713494961	0.525894574356562	0.282550392264243	0.577225599470649	0.436867521993949	NA	NA	0.571569139407278	0.674462646066225	77.8405833877792
a5323	loss_cnaOV1	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.5150611202235	3.94802992243893	-0.432968802215434	1.35900510604916	1.52885860892738	0.286070552777299	0.318592476428688	0.283197412558115	0.436884514176122	NA	NA	0.0680473727040996	0.649804317704	77.8405833877792
a5324	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-1.28558078964983	-2.06022496954581	0.774644179895972	2.07864468096704	2.03394716650234	0.380312833804764	0.372667915295455	0.380857572238752	0.436980702571902	NA	NA	0.276378384770496	0.590938209562061	77.8405833877792
a5325	NF1_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.11804126633136	1.65684399478253	-0.538802728451174	1.1447959790013	1.04915509615999	0.506705527879167	0.470653931647466	0.513558701114112	0.436983779268769	NA	NA	0.451324192254988	0.433030096796319	77.8405833877792
a5326	TP53_mut	186	Bexarotene	Retinioic acid X family agonist	11	7	2.07944154167984	NA	3.6333333034897	4.00969248330729	-0.376359179817587	0.96811593480728	0.985335743616542	0.386164269960383	0.388754245525881	0.381960344233745	0.437005839752367	NA	NA	0.806319434252323	0.440951431046366	77.8405833877792
a5327	loss_cnaOV82	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	2.7393120929408	3.28042915660943	-0.54111706366863	0.779169207942273	1.25645697154615	0.43978548454578	0.69447952787775	0.430668996967521	0.437019385808513	NA	NA	0.599382617846953	0.359374202227993	77.8405833877792
a5328	ARID1A_mut	1375	Temozolomide	DNA akylating agent	9	24	3.40119738166216	NA	5.81556082265972	5.99659554544627	-0.18103472278655	0.500293830100056	0.761426242091579	0.257378150918818	0.361856796735519	0.23775739891662	0.437200686668978	NA	NA	0.908324744863892	0.435549908742034	77.8474665343747
a5329	loss_cnaOV56	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.34643719009773	3.9419220100867	0.40451518001103	1.21012844416676	0.714954626420464	0.533593319681438	0.334274582141204	0.565791401387666	0.437387369388701	NA	NA	0.523834670847204	0.623373058951781	77.8474665343747
a5330	loss_cnaOV35	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.31958271118805	5.01430493104102	0.305277780147035	0.60078122477064	0.613763586245875	0.498780362146104	0.508134687903373	0.49738659475432	0.43744702367948	NA	NA	0.109136074982428	0.340628181902489	77.8474665343747
a5331	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	3.5539503332671	2.71270846605057	0.84124186721653	1.57304721139207	1.87935214970837	0.456834764479204	0.534784881931211	0.447623329851764	0.437485599986345	NA	NA	0.34431786049584	0.326459506841566	77.8474665343747
a5332	gain_cnaOV19	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-2.01392604469362	-0.96067602986265	-1.05325001483097	0.622688036197693	2.0262464714169	0.536242112842226	1.69145696336548	0.519803503516755	0.437544009044817	NA	NA	0.441677647973717	0.0772018331981928	77.8474665343747
a5333	gain_cnaOV51_(MYC)	1016	Temsirolimus	MTOR	8	23	-1.6094379124341	NA	-1.4369305496698	-2.23541965309851	0.798489103428703	1.44257088159927	1.55919408358392	0.521255713483122	0.553518106883924	0.51211655549213	0.437719346297097	NA	NA	0.037071018934789	0.209289485100507	77.8474665343747
a5334	loss_cnaOV16, loss_cnaOV17	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	2.91239392705722	2.20066538527985	0.71172854177737	0.3139558144761	1.28849035884984	0.58573319911241	2.26697041099568	0.552373975396051	0.437771383044906	NA	NA	0.385543473198948	0.0735367938449513	77.8474665343747
a5335	loss_cnaOV39	152	CP466722	ATM	9	23	2.77258872223978	NA	2.50239082818232	2.70347028116445	-0.201079452982133	0.795855242438666	0.822224109244622	0.246639789088837	0.252658325609546	0.244555530203152	0.437806591961628	NA	NA	0.554260061106919	0.533904318633149	77.8474665343747
a5336	loss_cnaOV21, loss_cnaOV22	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.643999716114	2.25648397394217	0.387515742171828	0.142302695603837	0.932469018686239	0.430326180913088	2.72317920983487	0.415580286750761	0.43786152327432	NA	NA	0.592794402344889	0.0575360883312718	77.8474665343747
a5337	loss_cnaOV34	1017	Olaparib	PARP1, PARP2	5	26	1.6094379124341	NA	3.77439968860736	4.00718215285031	-0.232782464242951	1.47047237893908	1.11923852011273	0.198290108850272	0.158304547284934	0.207982891992946	0.438091316355235	NA	NA	0.0815917682483942	0.750858942162927	77.8474665343747
a5338	loss_cnaOV36	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.524577723189636	-0.0156562751838256	-0.50892144800581	1.63202256238207	0.893103422807012	0.530004415547129	0.311834811439737	0.569834842202571	0.43818258096654	NA	NA	0.547271675200846	0.645158766979542	77.8474665343747
a5339	loss_cnaOV35	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	4.12416272406931	3.7784322450974	0.34573047897191	1.17097126713563	0.797535263585856	0.392449149678172	0.295251035337203	0.433498673672994	0.438214588258883	NA	NA	0.939491551198959	0.561182022944615	77.8474665343747
a5340	SMAD4_mut	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-0.312816510143341	-1.1366528782644	0.823836368121062	0.991922317140548	2.02605640523752	0.417334963348573	0.830545249244886	0.406620647871095	0.438251484174357	NA	NA	0.441692380471939	0.294865924063488	77.8474665343747
a5341	loss_cnaOV54	258	STF-62247	stimulates autophagy	10	21	2.32630161961136	NA	4.70615520426764	4.38631519819624	0.319840006071402	0.576298708345639	0.700602670709057	0.481310845791712	0.554989975579775	0.456521248695359	0.438277920479466	NA	NA	0.052451418311674	0.192870596674953	77.8474665343747
a5342	loss_cnaOV35	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-2.11462187194575	-2.84654613158697	0.731924259641223	1.80655008742187	1.75509666719934	0.415383660256222	0.405150272188552	0.417027889870691	0.438296161117503	NA	NA	0.695059520994849	0.438073363411828	77.8474665343747
a5343	loss_cnaOV85	1069	EHT 1864	Rac GTPases	7	26	2.30258509299405	NA	4.56937915215367	4.13777127777176	0.431607874381909	1.03590796172263	0.952695177869918	0.445251022992615	0.416646932285547	0.453038793947628	0.438370762729584	NA	NA	0.207789171645977	0.345981485141401	77.8474665343747
a5344	PIK3CA_mut	184	BMS-754807	IGF1R	5	12	0.940007258491471	NA	1.28583914579953	0.602232870435349	0.683606275364179	1.58651872561069	0.739557839980376	0.660156550018605	0.430884466933122	0.924344572403314	0.438500932913973	NA	NA	0.351144093667064	0.400704152343063	77.8560110357514
a5345	loss_cnaOV55	1006	Cytarabine	DNA synthesis	7	24	0.693147180559945	NA	0.242916611869616	-0.214625190507664	0.45754180237728	1.14180656225708	1.28274020711355	0.364609769584969	0.400717439802437	0.356690933861699	0.438804297776708	NA	NA	0.766156825197089	0.384410115168639	77.8821403468797
a5346	ARID1A_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	4.79822187542026	5.11515628813903	-0.316934412718772	1.07098611424372	1.22758301438633	0.265753473411193	0.295927658168169	0.258177580664236	0.438873334179342	NA	NA	0.79925703885774	0.599854854791592	77.8821403468797
a5347	gain_cnaOV26	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.01340129475777	4.43590829162374	-0.422506996865977	0.8067031727921	0.861914377098037	0.492168803133967	0.523745302009446	0.490196019572742	0.43893983839874	NA	NA	0.868999938167119	0.465101383764761	77.8821403468797
a5348	loss_cnaOV41	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	1.50456043372577	1.16454132585358	0.340019107872184	0.695200399567759	1.30411367013236	0.273673078285403	0.489095098454476	0.260728121834406	0.438976427938392	NA	NA	0.265065606629844	0.411451799711714	77.8821403468797
a5349	loss_cnaOV1	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.31337498797355	2.91575026998633	-0.602375282012781	0.275401849393967	1.15171396823755	0.540280178307823	2.18725939327688	0.523025072739706	0.43921508374101	NA	NA	0.388831620784799	0.0419127933146854	77.9099140377028
a5350	loss_cnaOV44	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.79075551854983	3.38048185552525	-0.589726336975423	1.2907513275618	1.22330799791072	0.480264668036969	0.456886097564123	0.482075109443094	0.439681356979852	NA	NA	0.993585118363109	0.516700075125512	77.9252733777903
a5351	loss_cnaOV38	1024	CEP-701	FLT3, JAK2, NTRK1, RET	8	23	0.693147180559945	NA	0.409989697195171	-0.355261595425998	0.765251292621169	1.43063359730161	1.63073626968186	0.4828843513577	0.534903761567286	0.469267352942644	0.439686757478119	NA	NA	0.0991890608492471	0.230025999040006	77.9252733777903
a5352	gain_cnaOV72_(ASXL1)	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-2.10106137812647	-1.43126041090841	-0.669800967218055	0.937379336534433	1.36327640344486	0.515902138929149	0.714546332645184	0.49131706932324	0.439745521366001	NA	NA	0.619329003840935	0.291411366427504	77.9252733777903
a5353	gain_cnaOV48_(SOX17)	308	XL-880	MET	3	29	1.63315443905142	NA	-0.221769943122987	0.302222712139265	-0.523992655262252	0.303068406599881	0.997001799444125	0.542228510052563	1.72895836006437	0.525568414775582	0.439797351605027	NA	NA	0.366342155923281	0.0726609020452286	77.9252733777903
a5354	PIK3CA_mut	1053	MK-2206	AKT1, AKT2	7	25	1.38629436111989	0.693147180559945	0.65478290619839	1.49332200782988	-0.838539101631493	1.12461120357971	1.18671685821176	0.713918570237359	0.745625776234817	0.706604187704111	0.439815208792102	NA	NA	0.0961953539845018	0.115479787321482	77.9252733777903
a5355	loss_cnaOV43_(NF1)	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.60479037833589	2.31654783508914	0.28824254324675	0.845816754596422	0.875015556980135	0.330864916179322	0.340786041042996	0.329414192636228	0.439913916337789	NA	NA	0.606446522669995	0.513664393941836	77.9252733777903
a5356	loss_cnaOV56	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.75942404607147	2.93229627636003	0.827127769711447	1.2427758855652	1.64050847533431	0.511507503572261	0.665548615255984	0.504189879020827	0.439945067433406	NA	NA	0.662155827787069	0.372032593458538	77.9252733777903
a5357	PIK3CA_mut	254	AC220	FLT3	6	26	0.0237165266173161	NA	2.68826054677883	2.46987152613818	0.218389020640648	0.376670967810788	0.667525289816117	0.347494336178925	0.579787239536737	0.327162167445083	0.439958694119119	NA	NA	0.857526062806023	0.29851983592342	77.9252733777903
a5358	PIK3R1_mut	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.6886850076854	-2.258224964514	-0.4304600431714	0.275145967356998	0.789784767958004	0.575595051408393	1.5644788375651	0.54503462289398	0.440231914081141	NA	NA	0.671945027723662	0.120773996328806	77.9461961253192
a5359	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.79039897097236	3.42668042622111	0.363718544751257	1.26639564111425	0.835215149985668	0.403011317862566	0.28720767266005	0.435478864047782	0.440241121693147	NA	NA	0.793416273462967	0.565239872548686	77.9461961253192
a5360	loss_cnaOV56	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.87953556796646	0.221282924961353	0.658252643005107	1.45335866970367	1.10568164021236	0.581833828357021	0.45291823465664	0.595336504709151	0.440422627085625	NA	NA	0.145268747138465	0.517858300315945	77.9513616780733
a5361	gain_cnaOV94	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	4.29974504871431	3.95791445725677	0.341830591457545	2.05126970682388	1.33093864844049	0.227449785492985	0.16664341618286	0.25683422136556	0.44061707321555	NA	NA	0.327794939086562	0.688396778559818	77.9513616780733
a5362	ARID1A_mut	1170	CCT018159	HSP90	9	24	2.30258509299405	NA	3.1876769103576	3.88518995601965	-0.697513045662045	0.886678732620584	1.28109837089549	0.585223674841239	0.786658143474966	0.544464860395131	0.440723701240213	NA	NA	0.196448724587841	0.091706063473833	77.9513616780733
a5363	SMARCA4_mut	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	4.59002823357538	4.97242653057548	-0.382398297000097	0.568327734225656	0.832148159289159	0.467651011354744	0.672848207066848	0.459531506176437	0.440734370486532	NA	NA	0.945764232608828	0.369308590775024	77.9513616780733
a5364	gain_cnaOV95_(MECOM)	258	STF-62247	stimulates autophagy	8	23	2.32630161961136	NA	4.64527934208815	4.43530158556923	0.209977756518921	0.572421174283965	0.705291248696851	0.310794575956065	0.366823880653226	0.297717796593806	0.440768337531471	NA	NA	0.0524775092876765	0.414448063616903	77.9513616780733
a5365	gain_cnaOV50	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	0.591756426428941	1.38962664518952	-0.797870218760576	0.865042489404302	2.43967057383645	0.342347721104064	0.922348010107592	0.327040145221698	0.440807706708847	NA	NA	0.361545999892828	0.230942402013835	77.9513616780733
a5366	loss_cnaOV83	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	2.67720370440016	1.99581516013012	0.68138854427004	0.747118451446743	1.65635910492091	0.44374576748683	0.912022107004022	0.411377304743693	0.440845383959375	NA	NA	0.947317830527471	0.253875592799113	77.9513616780733
a5367	ARID1A_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	2.33909827018804	2.42039787129319	-0.0812996011051537	0.769398415032071	1.05836694832952	0.0814681667223888	0.105666452538461	0.0768160808814689	0.441034083680588	NA	NA	0.406665213605738	0.858876171268077	77.9701976121704
a5368	PTEN_mut	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-3.21905673868057	-4.25472440015643	1.03566766147586	3.21014193746891	2.26482283577854	0.441646014071795	0.322623635231673	0.457284183608052	0.441257314313081	NA	NA	0.927729426179077	0.636054814288547	77.9939397603865
a5369	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-3.15546260349096	-4.2617904151775	1.10632781168654	2.50349548167612	2.32900913751901	0.472405355220855	0.441913244814741	0.475020812011524	0.441332780185828	NA	NA	0.927729692499092	0.529464879422935	77.9939397603865
a5370	loss_cnaOV36	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-1.29399460336346	-2.05938358817444	0.765388984810983	1.81634883874683	2.05152126124979	0.375712206172253	0.421388759958167	0.373083623001161	0.441477569935442	NA	NA	0.276472199735276	0.549310882837013	78.0049987573378
a5371	gain_cnaOV50	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	2.76230872018876	3.01743422028825	-0.255125500099492	0.905771542160388	1.0213064110221	0.252423811809149	0.281666500021609	0.249803092731169	0.441618054707058	NA	NA	0.0865372354893963	0.629939346961507	78.01529312812
a5372	PTEN_mut	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-4.42630009583966	-4.00547260842446	-0.420827487415194	0.61359548881389	1.60294933594032	0.274951415087915	0.685838626728946	0.262533242928935	0.441801363308297	NA	NA	0.863522034288457	0.354477445098697	78.0331474234261
a5373	PTEN_mut	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	1.50284711166291	0.612697545672367	0.89014956599054	1.49572734880502	2.36190556631257	0.384635412017578	0.595128227548762	0.376877712084082	0.442287311807882	NA	NA	0.94562161268636	0.422904699429356	78.0950797349832
a5374	MLL2_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	1.14614840859993	2.46368463980705	-1.31753623120712	1.39533077446454	1.52415262059929	0.868988707497948	0.94424652227192	0.864438517114561	0.442316619897865	NA	NA	0.240376043611957	0.237178951433353	78.0950797349832
a5375	loss_cnaOV16, loss_cnaOV17	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	6	27	-1.38629436111989	0.693147180559945	-1.67055846003781	-2.43774262220403	0.767184162166225	1.21601202712157	1.66358149271162	0.47952480348682	0.630901788021151	0.461164160293539	0.442540804412908	NA	NA	0.122936580106652	0.224056073167275	78.1059428948155
a5376	loss_cnaOV38	1069	EHT 1864	Rac GTPases	8	25	2.30258509299405	NA	4.54564061444403	4.12810329486357	0.417537319580459	1.34338530190359	0.828335365876051	0.430951738192314	0.310809801915209	0.504067961819872	0.442636378277678	NA	NA	0.207872472474233	0.428524200050705	78.1059428948155
a5377	gain_cnaOV18_(CCNE1)	1262	UNC1215	LMBL3	4	29	0	NA	3.01210668178032	2.74845491457528	0.263651767205046	0.136560834402852	0.514526822588092	0.537145258976217	1.93065433700615	0.51241598227837	0.442832523263998	NA	NA	0.108401328174969	0.0371278448878618	78.1059428948155
a5378	loss_cnaOV82	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	4.70037188989327	3.77023330698846	0.93013858290481	1.59280224450158	1.47367449747894	0.626173929065828	0.583963631465039	0.63116962700788	0.442998183455443	NA	NA	0.0681509842880312	0.422513722968631	78.1059428948155
a5379	loss_cnaOV85	1020	Lenalidomide	TNFA	7	24	1.6094379124341	NA	4.70504740943471	4.31093079324687	0.394116616187835	0.877434857157864	0.725636170202501	0.518891306778188	0.449169089844954	0.543132539930928	0.44306345771737	NA	NA	0.0422907463676625	0.307551351279165	78.1059428948155
a5380	PIK3CA_mut	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-3.46921331530316	-2.21574101222601	-1.25347230307715	0.924646756604254	2.16118733440735	0.645322496689971	1.355622884225	0.579992434307359	0.443245321018712	NA	NA	0.341653776391419	0.096666305879036	78.1059428948155
a5381	loss_cnaOV55	1043	JNK Inhibitor VIII	JNK	8	25	2.30258509299405	NA	4.27458614776649	4.49562016239073	-0.221034014624237	0.8616976003612	1.05321917948225	0.218166877451491	0.25650995724206	0.209865162855177	0.443312446142087	NA	NA	0.373124690416751	0.559970121151938	78.1059428948155
a5382	gain_cnaOV95_(MECOM)	1268	XAV 939	TNKS1 (tankyrase-1)	8	24	1.6094379124341	NA	2.58482413934313	2.94620884096628	-0.361384701623151	1.38788418369741	0.951126395134423	0.338021779843313	0.260385344734168	0.379954445036799	0.443353085997424	NA	NA	0.304930071870468	0.510170981982417	78.1059428948155
a5383	loss_cnaOV40	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	5.42388088245422	4.92718492541539	0.49669595703883	1.00623001853299	1.21690545271815	0.420053755375076	0.493620690985724	0.408163145238097	0.443424938997263	NA	NA	0.799331740483964	0.436580235826967	78.1059428948155
a5384	BRCA1_mut	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	9.16478164307352	8.68807077189028	0.476710871183245	0.688992894165849	1.2827228139407	0.386121052740232	0.691895192562748	0.371639816492172	0.443604485333917	NA	NA	0.528248535807897	0.29951540248984	78.1059428948155
a5385	loss_cnaOV33_(ZFHX3)	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-5.01909520854819	-4.01762877638741	-1.00146643216078	0.866351424024314	2.45880061363953	0.427869111194037	1.1559586611041	0.407298756395868	0.443635801716481	NA	NA	0.927737785831704	0.146892078817115	78.1059428948155
a5386	loss_cnaOV35	292	Masitinib	KIT	5	27	2.99573227355399	NA	3.80758093943178	4.05165736129489	-0.244076421863103	0.675238225265615	1.10169189554246	0.231387099490352	0.361467127793442	0.221546897867414	0.443956565163538	NA	NA	0.103388628073127	0.525626997766716	78.1059428948155
a5387	loss_cnaOV70	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.91158727497916	2.25214739250596	0.659439882473208	0.855172292911214	1.47560509469705	0.457128939263812	0.771119326408851	0.446894555218783	0.44401615015834	NA	NA	0.820250071350199	0.318223055458615	78.1059428948155
a5388	gain_cnaOV51_(MYC)	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	3.14940103808867	3.653149200318	-0.503748162229328	2.12818725825668	1.58232527076452	0.294654708017269	0.236702931227009	0.318359424283185	0.444130572449878	NA	NA	0.697366394845272	0.577067073025491	78.1059428948155
a5389	loss_cnaOV83	151	QS11	ARFGAP	4	15	2.32630161961136	NA	4.43858911105785	3.58763024039077	0.850958870667073	1.84486545499833	1.32722869319148	0.594147185246487	0.461257956975428	0.641154666887772	0.44415988865779	NA	NA	0.0628971709637034	0.437479052377363	78.1059428948155
a5390	loss_cnaOV85	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	6	13	2.07944154167984	NA	3.19792756288972	3.58728912573892	-0.389361562849202	1.00044709448109	1.15285418265313	0.350712183936716	0.389187559239359	0.337737043164593	0.444162236746363	NA	NA	0.771412264967609	0.468280864707841	78.1059428948155
a5391	loss_cnaOV55	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	2.69303927944685	1.82485750342841	0.86818177601844	1.67320728759197	2.0470300197568	0.441559381990913	0.518872815374777	0.424117754815137	0.444181692809746	NA	NA	0.130985121749254	0.249707678369606	78.1059428948155
a5392	loss_cnaOV20	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.82702588159146	4.37328799406939	0.453737887522077	1.11590796209463	0.986235404821152	0.45197114667822	0.406608701554903	0.460070572709118	0.444184788573065	NA	NA	0.373142635792088	0.431970877404517	78.1059428948155
a5393	loss_cnaOV41	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.39866814242675	0.744800188989497	0.65386795343725	1.05940310219349	1.37088485482189	0.489867880919379	0.617204114357809	0.476967814720078	0.444210560124223	NA	NA	0.161768536953501	0.267137364131255	78.1059428948155
a5394	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.58652570908148	2.29860253902064	0.287923170060843	0.703746863507006	0.905864584739151	0.331247305835711	0.409128885670659	0.317843499913127	0.444215189815415	NA	NA	0.606516508078312	0.388285435440404	78.1059428948155
a5395	TP53_mut	1149	TW 37	BCL2, BCL2L1	23	10	1.6094379124341	NA	-0.683210373731664	-0.871911124594779	0.188700750863116	0.952636058728665	0.860480476611707	0.203598970979527	0.198082729636484	0.219296957911419	0.444244800788068	NA	NA	0.0412193243902336	0.581964829710825	78.1059428948155
a5396	loss_cnaOV1	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.91117602286352	2.25218993582826	0.65898608703526	0.854581784416842	1.47564921473936	0.456808413648562	0.771121148439813	0.446573671068334	0.444321546853258	NA	NA	0.820252501706242	0.318246787088461	78.1059428948155
a5397	PTEN_mut	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	2.48898241222807	3.1477012759409	-0.658718863712829	0.411597414869828	0.936520963859832	0.732548448563739	1.60039601784466	0.703367985483151	0.444350028064802	NA	NA	0.237138134018588	0.0390270243946158	78.1059428948155
a5398	loss_cnaOV33_(ZFHX3)	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.12835599417107	4.70115821551842	0.427197778652658	0.532626368537789	1.28588732073134	0.347441465280848	0.802059011508269	0.332220227826566	0.444377627632266	NA	NA	0.42300968776431	0.268300239197204	78.1059428948155
a5399	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-1.61939280292847	-2.41947991232476	0.800087109396295	1.83838624085094	1.56351298041538	0.499544450267663	0.435211650096965	0.511723995526876	0.444499449532481	NA	NA	0.122967351568832	0.401090679271861	78.1059428948155
a5400	loss_cnaOV1	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	3.06374689461954	1.93619495289648	1.12755194172305	2.45410329522115	1.93645144309942	0.570858391049123	0.459455779191824	0.582277415600119	0.444525605721643	NA	NA	0.130990858967834	0.512838326957154	78.1059428948155
a5401	loss_cnaOV56	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	4.91589264220112	5.2192379776916	-0.30334533549048	0.355488864905504	0.793770616202002	0.3927670731393	0.853318810903164	0.38215742596005	0.4446007390039	NA	NA	0.331751135152171	0.289192182794237	78.1059428948155
a5402	loss_cnaOV56	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	3.13019266947748	2.2652802137193	0.864912455758182	2.28461891940913	1.47994874857731	0.559971338425623	0.378580623845081	0.584420546042309	0.444841117485326	NA	NA	0.240426668378803	0.581851238437447	78.1337052416782
a5403	loss_cnaOV39	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	9	23	2.99573227355399	NA	4.23465255524037	3.95366103370678	0.280991521533585	1.54420589350141	1.48953133847142	0.186791522956025	0.18196506224727	0.188644249554321	0.444956350509468	NA	NA	0.327888451598295	0.647305090345967	78.1376754271236
a5404	loss_cnaOV52, loss_cnaOV53	1017	Olaparib	PARP1, PARP2	8	23	1.6094379124341	NA	4.38535421248596	3.82503916161987	0.560315050866087	0.946130459186388	1.20725390307592	0.487371531718574	0.592217537682828	0.464123619263918	0.44502842440872	NA	NA	0.0816862700565309	0.199966802615881	78.1376754271236
a5405	loss_cnaOV16, loss_cnaOV17	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	6	26	2.30258509299405	NA	1.24041476820429	0.783599854158887	0.456814914045401	2.12246902402295	0.976329025509369	0.36749665590277	0.215228071116698	0.467890334210921	0.445467624176264	NA	NA	0.844300001899165	0.62673431006489	78.1782143773465
a5406	SMARCA4_mut	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.711960480324417	0.632387121484276	0.0795733588401406	0.631081517754999	0.621208267706879	0.127957908668924	0.126090459950743	0.128094494192546	0.44552216413716	NA	NA	0.0147477762192924	0.851317026329047	78.1782143773465
a5407	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	305	TPCA-1	IKK	5	27	2.99573227355399	NA	2.93297283264525	3.3978287482465	-0.464855915601244	1.23644458701291	1.22713379407334	0.378430271128668	0.375961786305585	0.378814370402272	0.445557040015858	NA	NA	0.993586826610085	0.471009006396937	78.1782143773465
a5408	loss_cnaOV85	1175	AG-014699	PARP1, PARP2	7	26	1.6094379124341	NA	4.25306579409407	3.80641350816358	0.446652285930489	1.42513405296414	0.961296300668332	0.418634481944164	0.313410717399879	0.4646353945396	0.445735832761662	NA	NA	0.314641947874967	0.457724664431488	78.1782143773465
a5409	loss_cnaOV55	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-3.25494366073897	-2.61188417491522	-0.643059485823756	0.794180091111823	1.28416347347069	0.530500877798897	0.8097149412591	0.500761389892026	0.445752852208053	NA	NA	0.375552219060577	0.249792177273697	78.1782143773465
a5410	loss_cnaOV70	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.98029704934915	4.39686982014005	0.583427229209105	0.611597537202414	0.997647660442903	0.597363742123943	0.953939794914534	0.584802884166634	0.445753677929267	NA	NA	0.0307006692168721	0.233242777157211	78.1782143773465
a5411	gain_cnaOV26	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	3.03371780230949	3.37314581758237	-0.339428015272874	1.32778544836897	0.926887871069877	0.345446031352835	0.255634685324969	0.366201809158516	0.445971307702949	NA	NA	0.186903681009543	0.706991726609437	78.193217175208
a5412	gain_cnaOV19	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.56616034918375	5.15196890455547	0.414191444628286	0.651587758756669	0.775273745843763	0.539558886678825	0.635664864881176	0.534251865033175	0.446245298761322	NA	NA	0.331786246883013	0.389104630354417	78.193217175208
a5413	loss_cnaOV38	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	0	NA	-1.68815578298902	-2.08632980765646	0.398174024667439	1.9129406471376	2.07839206285002	0.194972693522544	0.208147610467288	0.191577918230422	0.446257473602313	NA	NA	0.276570324315565	0.624514266638132	78.193217175208
a5414	PIK3R1_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.29686700632327	4.54348669191725	-0.246619685593982	0.31809300486902	0.971748600706547	0.266389964255217	0.775306849943246	0.253789596830566	0.446284360990721	NA	NA	0.526796525146078	0.332210584474479	78.193217175208
a5415	loss_cnaOV84	291	KIN001-266	MAP3K8 (COT)	6	26	2.99573227355399	NA	3.6210736517636	3.22891062466822	0.392163027095379	0.501903088741478	1.18932939354197	0.354940365611247	0.781352089461588	0.329734579187914	0.446292281279755	NA	NA	0.950737861907604	0.221261072177365	78.193217175208
a5416	gain_cnaOV26	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.77847907862171	-3.58363325762417	0.80515417900246	2.65551301915189	1.61004934390213	0.45605506174264	0.303200990993299	0.500080436697102	0.44640686252353	NA	NA	0.679216883348737	0.656358602734723	78.193217175208
a5417	loss_cnaOV85	207	AS601245	JNK 	5	13	2.07944154167984	NA	2.22214173145427	1.90552009898232	0.31662163247195	1.03501910454274	0.976651873994765	0.319314787073621	0.305908974126453	0.324190882035462	0.446416091781941	NA	NA	0.476097431427792	0.573659775787914	78.193217175208
a5418	loss_cnaOV84	231	FMK	RSK	5	15	2.99573227355399	2.32630161961136	5.55861648431883	5.13760171219273	0.421014772126107	0.767822314116144	0.715720800945273	0.578617910769742	0.548323178925511	0.588238837784315	0.446554616191988	NA	NA	0.124117744075373	0.318733854286564	78.2030441959914
a5419	SMAD4_mut	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.33368016140576	-2.82481229890418	0.491132137498416	1.36526661374271	1.20962300420609	0.399633119299231	0.359733500075885	0.40602083111073	0.446859148075572	NA	NA	0.37559458258394	0.606894857060756	78.2142814797094
a5420	loss_cnaOV54	283	GSK2126458	PI3K, MTOR	10	22	-2.05572501506252	0.0237165266173161	-3.03491290452413	-2.59457844851526	-0.440334456008873	1.79808699341414	1.7589624775631	0.24866545824922	0.244890518435253	0.250337606188689	0.446914465003495	NA	NA	0.695172355945839	0.526535707836078	78.2142814797094
a5421	gain_cnaOV72_(ASXL1)	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	2.60793824979425	2.23440499643148	0.37353325336277	2.28380300464535	0.857408532147589	0.302394649870394	0.163557562803354	0.435653762888462	0.44693622401558	NA	NA	0.385897919633802	0.767784682320886	78.2142814797094
a5422	loss_cnaOV82	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.90764479412561	2.25255523535288	0.65508955877273	0.85472429663894	1.47581176996088	0.454056725146891	0.766433762733504	0.443884221624072	0.446948512900607	NA	NA	0.82027329963511	0.320762862624908	78.2142814797094
a5423	gain_cnaOV4_(KRAS)	175	PAC-1	CASP3 agonist	6	12	0.940007258491471	NA	1.77134753369115	2.32392649715554	-0.552578963464391	1.42678967709604	1.31576837322378	0.408880817905288	0.387288310488103	0.41996674696665	0.447178687761582	NA	NA	0.891434757231048	0.446452745954245	78.2224971459632
a5424	loss_cnaOV56	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.90723354200996	2.25259777867518	0.654635763334781	0.854130631050196	1.47585587164829	0.453736319186457	0.766435179276821	0.443563477918519	0.447254996280891	NA	NA	0.820275713597529	0.320787330020349	78.2224971459632
a5425	loss_cnaOV21, loss_cnaOV22	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.11448545717638	4.78044935142498	0.334036105751403	0.943019041089074	0.730631913815615	0.447366035691864	0.354219895035874	0.457187948452661	0.447714145333861	NA	NA	0.764350390944073	0.605931120989423	78.2224971459632
a5426	gain_cnaOV48_(SOX17)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.708569372809282	1.40754008163826	-0.698970708828978	0.428771026211294	1.3906985722879	0.51906225584738	1.63017243726849	0.502604031353157	0.447747355172336	NA	NA	0.579376287997463	0.0877071607892493	78.2224971459632
a5427	gain_cnaOV72_(ASXL1)	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	2.94607640952799	3.3684346705302	-0.422358261002215	0.835419985636552	1.14064092426775	0.382284365490908	0.505563989686454	0.370281525076224	0.44776450579491	NA	NA	0.950741094817616	0.361711636200182	78.2224971459632
a5428	loss_cnaOV55	1067	CCT007093	PPM1D	8	25	1.88706964903238	NA	4.73482080595681	4.41129830190862	0.323522504048183	0.310110486594181	0.767494966338213	0.46806133496559	1.0432491580704	0.421530457185587	0.447829019757681	NA	NA	0.0804085314231978	0.0970280450924658	78.2224971459632
a5429	gain_cnaOV51_(MYC)	262	VX-11e	ERK	8	24	1.63315443905142	NA	2.53548761462691	2.96720757818787	-0.431719963560963	1.11117541687931	1.1135021222239	0.387902616166973	0.388525481218287	0.387713642340192	0.447855681241927	NA	NA	0.389014412265053	0.36018304590137	78.2224971459632
a5430	KRAS_mut	1527	GDC0941 (rescreen)	PI3K	7	24	1.38629436111989	NA	0.621628228236219	0.312471725290448	0.309156502945771	1.09051624648512	0.855558704840433	0.340044005362286	0.283495549875781	0.361350426565329	0.447863008750902	NA	NA	0.909302252557748	0.508700192862607	78.2224971459632
a5431	loss_cnaOV20	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-2.92370696389463	-3.80486582328582	0.881158859391193	2.4797012402026	1.60541258535896	0.513307070332358	0.35534879972847	0.548867541856332	0.448039579530491	NA	NA	0.243390940701752	0.534795799475823	78.2224971459632
a5432	gain_cnaOV51_(MYC)	1268	XAV 939	TNKS1 (tankyrase-1)	8	24	1.6094379124341	NA	2.52705839323446	2.96546408966918	-0.438405696434715	1.17529960972829	1.02684409043707	0.412291491833262	0.373016116746663	0.426944752876857	0.448069441955775	NA	NA	0.305030496337671	0.366786040270097	78.2224971459632
a5433	SMARCA4_mut	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-0.0666184785177772	-1.1621216401567	1.09550316163893	4.08231650922374	1.71294356468716	0.558350240659449	0.268353313410095	0.639544223302534	0.448175431526977	NA	NA	0.441895233067874	0.688882704849097	78.2224971459632
a5434	PIK3R1_mut	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	3.12878782204136	2.7914422644257	0.337345557615651	2.08664777147603	1.82733567547446	0.180979755664424	0.161668664077898	0.184610612129631	0.448241313207992	NA	NA	0.344549262245559	0.748384256941915	78.2224971459632
a5435	loss_cnaOV44	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.95727284792777	1.24292110328802	0.71435174463975	1.05975771677727	1.21889031511842	0.590894244475068	0.674070811970212	0.586067290698218	0.448339701236487	NA	NA	0.0963173011288421	0.365059076168798	78.2224971459632
a5436	loss_cnaOV20	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.5697644187878	2.90614970587838	0.663614712909428	0.990838074742084	1.69296716732113	0.410383134792593	0.6697509207871	0.39198321486618	0.448358628285783	NA	NA	0.662275620851577	0.258077077729643	78.2224971459632
a5437	loss_cnaOV58	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	2.92630967060542	2.46753297669253	0.458776693912886	0.945577357470698	1.04169194081981	0.445503253529496	0.485181556313971	0.44041494028631	0.44844839748537	NA	NA	0.393446617626864	0.364056975959165	78.2224971459632
a5438	loss_cnaOV52, loss_cnaOV53	164	JQ12	HDAC	5	14	1.63315443905142	NA	1.05548858841368	2.05760893926971	-1.00212035085602	2.19853266489231	2.19396534234805	0.456538358101864	0.455813264391553	0.456762160966283	0.448883483224999	NA	NA	0.658190377624591	0.410095995881978	78.2224971459632
a5439	loss_cnaOV38	221	TAK-715	p38a	8	24	2.99573227355399	2.32630161961136	4.52437676308384	4.19579474237202	0.328582020711818	1.3407712902673	0.699172984891209	0.368696656782631	0.245069403780499	0.469958118823691	0.448887849129496	NA	NA	0.520010202748022	0.52485432840824	78.2224971459632
a5440	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.09408444056152	0.278132764333814	0.815951676227703	1.72905010033347	1.66692326825417	0.488219022857188	0.471907480338677	0.489495642521253	0.448984627935849	NA	NA	0.836593191704902	0.504797804026054	78.2224971459632
a5441	RB1_mut	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.388272268252765	-0.164835896209105	0.55310816446187	1.30045827359338	1.25595190708654	0.439298342877888	0.425317886542825	0.440389605160064	0.449067268433433	NA	NA	0.76626558524971	0.543945305955611	78.2224971459632
a5442	gain_cnaOV4_(KRAS)	230	GSK429286A	ROCK2	8	24	2.99573227355399	2.32630161961136	5.76834942574393	5.46221125644746	0.306138169296471	0.714380145449453	1.04636122478027	0.312698477820225	0.4285367828971	0.292574076758967	0.449130756094587	NA	NA	0.302427786930972	0.367062577208584	78.2224971459632
a5443	TP53_mut	1042	BIRB 0796	p38, JNK2	23	10	2.30258509299405	NA	4.47554278903166	4.21799684852574	0.257545940505928	0.895703818918515	0.761563458365113	0.299848336377452	0.28753471300021	0.338180538571027	0.449345190719581	NA	NA	0.869058742312157	0.40801454466757	78.2224971459632
a5444	loss_cnaOV39	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	1.6094379124341	NA	1.58782414367932	1.25366248934194	0.334161654337383	1.76359798665258	1.19612921905548	0.246606420557829	0.189477226026801	0.279369192737598	0.449359678725355	NA	NA	0.579404271255137	0.630272627303395	78.2224971459632
a5445	loss_cnaOV55	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.84920974037874	1.54874828755882	0.300461452819913	0.468123554253892	0.720157553055526	0.443619318269601	0.641842201892182	0.417216276556564	0.449368920626322	NA	NA	0.207424797980687	0.207685364401664	78.2224971459632
a5446	TP53_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	23	10	-2.30258509299405	NA	-0.205345640036538	-0.6251749820281	0.419829341991562	1.38593916498335	1.44945092668858	0.29888028397337	0.302920469093322	0.289647158286832	0.449463083441145	NA	NA	0.888578590776097	0.449411262567102	78.2224971459632
a5447	gain_cnaOV18_(CCNE1)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.42797821839367	5.10164782837296	0.32633039002071	0.190325930739973	0.609147774210044	0.561656641452957	1.71458712300505	0.53571629715614	0.449499833199716	NA	NA	0.0116085727364152	0.0455206732623461	78.2224971459632
a5448	loss_cnaOV55	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	4.19497387272978	3.83961526423882	0.35535860849096	0.908343879959698	1.29146750592916	0.290778241664357	0.391215944017508	0.275158768501337	0.449510073256345	NA	NA	0.697660690605453	0.425524764422354	78.2224971459632
a5449	gain_cnaOV4_(KRAS)	283	GSK2126458	PI3K, MTOR	8	24	-2.05572501506252	0.0237165266173161	-2.31184111472756	-2.87229691644819	0.560455801720627	1.72868116004194	1.77667215287158	0.317432419195771	0.32421004791134	0.31545257284231	0.449550495575567	NA	NA	0.695206190844523	0.445231074263272	78.2224971459632
a5450	gain_cnaOV18_(CCNE1)	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	5.15006014226853	4.81863584696638	0.331424295302158	0.496161060890637	0.627011782880646	0.538743223684233	0.667977238494356	0.528577459548708	0.449555942571141	NA	NA	0.0488725507298203	0.287560091011423	78.2224971459632
a5451	loss_cnaOV85	1021	Axitinib	PDGFR, KIT, VEGFR	7	23	0.693147180559945	NA	2.88830509980764	2.41479352602338	0.473511573784253	0.892470601798228	1.06072632336217	0.461065233744747	0.530562656999772	0.446403151647419	0.449596049353574	NA	NA	0.193967449464665	0.263819122777623	78.2224971459632
a5452	loss_cnaOV84	1069	EHT 1864	Rac GTPases	6	27	2.30258509299405	NA	4.58898474844109	4.14939995542573	0.439584793015354	1.13335677488768	0.936146588239603	0.452868079904025	0.387860912605315	0.469568333141053	0.449599764448216	NA	NA	0.208005846568384	0.407073790560466	78.2224971459632
a5453	loss_cnaOV87, loss_cnaOV88	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.61973346389555	4.29824271328911	0.321490750606437	0.76610369671154	0.568377450054251	0.550341116766703	0.419643909808058	0.565628968172034	0.449628811902388	NA	NA	0.25225631443076	0.546195527224451	78.2224971459632
a5454	gain_cnaOV4_(KRAS)	298	OSI-930	KIT, VEGFR, PDGFR	8	24	2.32630161961136	NA	4.66791505965951	4.37944981061804	0.288465249041471	0.722839946651289	1.05057331671803	0.293180965244993	0.399072091101008	0.274578884168342	0.449686472633611	NA	NA	0.0307276532983764	0.398815801028623	78.2224971459632
a5455	gain_cnaOV51_(MYC)	158	PF-562271	FAK	5	13	0.940007258491471	NA	2.660715873216	2.14664135597361	0.514074517242398	1.21588607491103	1.4468432930956	0.36912096740148	0.422798260338671	0.355307668560642	0.44972872569494	NA	NA	0.745117269360488	0.466990364944481	78.2224971459632
a5456	loss_cnaOV58	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.59979369210859	4.83123310708863	-0.231439414980045	1.02044991650653	0.590440532805047	0.348520233055929	0.226801346382945	0.391977518685124	0.449798456838906	NA	NA	0.761246234079764	0.645648439714969	78.2224971459632
a5457	loss_cnaOV82	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	2.28770319006465	2.96921462835648	-0.681511438291833	0.145452121607066	1.28413843447579	0.549090604048329	4.68546921668775	0.530714929165746	0.449899775690653	NA	NA	0.229929971784036	0.0115494857591615	78.22577949811
a5458	loss_cnaOV54	200	LAQ824	HDAC	6	13	0.0237165266173161	NA	-3.14746941859011	-2.56255544270334	-0.584913975886763	0.67004494808075	1.37343201328999	0.483488498291376	0.872947371011702	0.42587763371383	0.450199651943239	NA	NA	0.375721514420407	0.229387815103902	78.2493080803016
a5459	loss_cnaOV34	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	4.7890359797363	4.4362801463103	0.352755833425999	0.784498884624635	0.679188548665303	0.508531169713107	0.449657533413555	0.519378358364862	0.450248906869367	NA	NA	0.0804383255625489	0.38736373382377	78.2493080803016
a5460	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.34234918377129	2.82432794540639	-0.481978761635099	0.540807672687854	1.79658833376012	0.286185131204202	0.891220272892263	0.268274458081532	0.450282503549297	NA	NA	0.319570518017869	0.265320425785479	78.2493080803016
a5461	loss_cnaOV70	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.53257056601483	3.94540350557023	-0.412832939555403	1.38900661143759	1.52678375159025	0.272640539178371	0.297214524506927	0.270393851863703	0.450667359061093	NA	NA	0.0682780103208086	0.670422863370466	78.3018466023271
a5462	gain_cnaOV95_(MECOM)	330	XMD13-2	RIPK	9	23	2.32630161961136	NA	3.84054517539581	4.17929581487665	-0.338750639480835	1.09225770736567	1.12792382418325	0.30285503001715	0.310138017059949	0.300331132491264	0.450757956480158	NA	NA	0.818988468387344	0.446559105115434	78.3032489525639
a5463	loss_cnaOV40	1017	Olaparib	PARP1, PARP2	7	24	1.6094379124341	NA	4.40686867258709	3.8421105712098	0.564758101377292	1.09220405176421	1.16670840732577	0.490373697048814	0.517081126429673	0.484061054014159	0.451033701156545	NA	NA	0.0817663052808759	0.262486250535662	78.3368076882176
a5464	loss_cnaOV38	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	8	23	2.30258509299405	NA	1.82505847713844	1.26431765918873	0.560740817949713	2.28646838961491	1.06614225281613	0.384736617011929	0.245243197105451	0.525953095347792	0.451379959630169	NA	NA	0.474810558313263	0.522244830337357	78.3782394929306
a5465	loss_cnaOV39	1166	QL-VIII-58	MTOR, ATR	7	16	2.30258509299405	NA	-0.679821181352174	-1.39509293530912	0.715271753956944	1.46294078388807	1.22824315321975	0.550364968742376	0.48892734540899	0.582353544639685	0.451513025016125	NA	NA	0.0481970441483621	0.28476112260431	78.3782394929306
a5466	loss_cnaOV52, loss_cnaOV53	256	JW-7-24-1	LCK	8	24	2.32630161961136	NA	1.6475647731743	2.03660401725156	-0.389039244077253	1.22876955726565	1.37431153814864	0.289945985436688	0.316608791108864	0.283079369763086	0.451520065436185	NA	NA	0.838477364900899	0.464934814763267	78.3782394929306
a5467	SMARCA4_mut	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.02622753221926	2.43153052288932	-0.405302990670064	0.933453101457065	0.94314954834747	0.430026859419061	0.434197486769726	0.429733536298895	0.451654982166116	NA	NA	0.73388690060546	0.536674684655386	78.3863259581155
a5468	gain_cnaOV50	290	KIN001-260	IKK	4	27	2.99573227355399	NA	5.19947937321483	4.79850820608251	0.400971167132318	1.36201801917488	0.828932234948388	0.44608766526845	0.294394906298838	0.483720080155025	0.451805162184826	NA	NA	0.664193306125397	0.602838337654889	78.3863259581155
a5469	gain_cnaOV49	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	1.39154487031024	1.99601310305176	-0.604468232741524	0.505246457806931	1.38117628967343	0.450858517999744	1.19638292045683	0.437647414932417	0.451814491001941	NA	NA	0.838479423552148	0.17041622246866	78.3863259581155
a5470	MLL2_mut	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	3.4475091277389	4.30750599679749	-0.859996869058594	1.40679548288695	0.913151101029828	0.902647888080197	0.611316200201149	0.941790321545593	0.451936250111878	NA	NA	0.208049886847909	0.401145440205518	78.3931161376851
a5471	loss_cnaOV81_(RB1)	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	4.97746107469255	4.4702763337185	0.507184740974046	0.456570090352942	1.05457604719184	0.50175423925835	1.11085844581273	0.480937095361301	0.452024750358067	NA	NA	0.189812083761453	0.129485094033079	78.3941357882855
a5472	loss_cnaOV56	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.346442523104399	-1.41784283421186	1.07140031110746	2.22470406350881	1.83066470557145	0.576166171585042	0.481592283972209	0.585252071472595	0.452266168080002	NA	NA	0.0731554567373573	0.495246175912985	78.4062846773576
a5473	loss_cnaOV21, loss_cnaOV22	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.96083007610984	1.57864431528594	0.382185760823899	0.65975262117091	0.681068555093931	0.562312183233114	0.579286460651883	0.561156080346697	0.452335180934066	NA	NA	0.207482552552514	0.42479964022804	78.4062846773576
a5474	loss_cnaOV21, loss_cnaOV22	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.49912486022455	4.88786658844334	-0.388741728218784	0.719361779027823	0.91380977008094	0.43109858236096	0.540398085569888	0.425407717171104	0.452342705793864	NA	NA	0.664200982774538	0.456334395603984	78.4062846773576
a5475	BRCA1_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.95436957351452	0.508126388560926	0.446243184953594	0.908910776376677	1.24316618356459	0.367924131704849	0.490964786150428	0.358956984877162	0.452671842976487	NA	NA	0.429240570935443	0.425808971918543	78.4300249205949
a5476	PIK3CA_mut	305	TPCA-1	IKK	6	26	2.99573227355399	NA	3.0337574199337	3.39244984024152	-0.358692420307818	1.17098929835533	1.24411908618097	0.291091577514285	0.306315711690625	0.288310358945528	0.452758626709841	NA	NA	0.993588872713331	0.523128260963802	78.4300249205949
a5477	loss_cnaOV70	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-1.47016209401655	-1.13348744761807	-0.336674646398478	0.750547982042728	1.38675861258968	0.251389998297	0.448571782822155	0.242778118226185	0.452798312655151	NA	NA	0.048213767091285	0.558511110758246	78.4300249205949
a5478	loss_cnaOV54	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	6	13	-0.669430653942629	NA	-4.52991140562464	-3.72978944917176	-0.80012195645288	1.27652564101681	1.97797247570398	0.444447286931983	0.626796619467467	0.404516223699276	0.452825080003206	NA	NA	0.587968692076611	0.307381413755347	78.4300249205949
a5479	TP53_mut	1031	Elesclomol	HSP70	21	10	-1.6094379124341	NA	-3.91087655682428	-4.37245531175093	0.461578754926652	1.46702540524472	1.6352214179361	0.303427565837205	0.314635829261359	0.282272938614782	0.452892967288685	NA	NA	0.863591248165083	0.458811967796307	78.4300249205949
a5480	loss_cnaOV33_(ZFHX3)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.42652347353015	5.10185564906774	0.324667824462402	0.800977543384462	0.551308619700993	0.558690671996855	0.40533948441369	0.588903951181624	0.453023646921206	NA	NA	0.0116201574055059	0.483485899414832	78.4335297141749
a5481	gain_cnaOV95_(MECOM)	1043	JNK Inhibitor VIII	JNK	8	25	2.30258509299405	NA	4.69019949470635	4.36262389136997	0.327575603336377	0.894725386332465	1.03807070996236	0.325141363219827	0.366118597214649	0.315561936381247	0.453078532624611	NA	NA	0.373322516624214	0.401656888129657	78.4335297141749
a5482	loss_cnaOV85	222	BX-912	PDPK1 (PDK1)	7	25	2.32630161961136	NA	3.7950072732067	3.30209196954073	0.492915303665966	1.47277097495861	1.13925677647477	0.406254686457275	0.334685644982797	0.432663920763506	0.453262019082212	NA	NA	0.325073243205867	0.435887073098172	78.4509802419242
a5483	loss_cnaOV40	193	GW-2580	CSF1R (cFMS)	7	25	2.99573227355399	NA	5.92802266517362	5.67004082865822	0.257981836515397	0.779557231455002	0.545069669306695	0.430434698119173	0.330933799477284	0.47330066419498	0.45347790620792	NA	NA	0.190833255732171	0.436176620300386	78.4615724925795
a5484	loss_cnaOV85	1004	Vinblastine	Microtubules	7	24	-2.30258509299405	NA	-2.66372842118424	-3.50519710070419	0.841468679519942	1.93051777585163	1.76683411680969	0.466984476238633	0.435877198358733	0.476257884944713	0.453488603430287	NA	NA	0.138075525427119	0.327772473145268	78.4615724925795
a5485	gain_cnaOV72_(ASXL1)	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	2.85301294982045	2.36310372347031	0.489909226350134	1.0721256431005	1.5094619049049	0.335842792064121	0.456951318628436	0.324558854223618	0.453729558011515	NA	NA	0.238514752575733	0.409914987818711	78.487067443769
a5486	gain_cnaOV18_(CCNE1)	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.70330365624032	2.34928046912453	0.35402318711579	0.879966257321013	0.949355815112346	0.375562945945039	0.40231450259648	0.372908851960732	0.453813932210612	NA	NA	0.733911040249306	0.496976330104069	78.487067443769
a5487	SMARCA4_mut	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	1.75278902838079	2.37202307318855	-0.619234044807756	1.88242466576002	1.40766849401333	0.428778219219223	0.328955551885388	0.439900479012848	0.453975128839205	NA	NA	0.820327996152667	0.630003503633951	78.487067443769
a5488	loss_cnaOV41	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	0.0946174342519933	1.00679063637687	-0.912173202124875	1.57217577474977	2.13571259007669	0.441806068848762	0.580197975808434	0.427104848453472	0.454122391286638	NA	NA	0.414235426256851	0.302567214743548	78.487067443769
a5489	SMAD4_mut	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	4.59222427800858	3.80919209829517	0.783032179713415	1.47885005562322	1.59385618682253	0.493655216304409	0.529487203071056	0.491281576209486	0.454176139995103	NA	NA	0.714618628229474	0.461400493845653	78.487067443769
a5490	loss_cnaOV41	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.38105543535084	0.855329169758034	0.525726265592809	0.969057473735976	1.29855440641746	0.414821525975355	0.542512987971698	0.404855016466518	0.454297569864586	NA	NA	0.957313791498325	0.382300036493183	78.487067443769
a5491	loss_cnaOV42	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.38105543535084	0.855329169758034	0.525726265592809	0.969057473735976	1.29855440641746	0.414821525975355	0.542512987971698	0.404855016466518	0.454297569864586	NA	NA	0.957313791498325	0.382300036493183	78.487067443769
a5492	loss_cnaOV39	211	TL-2-105	CRAF	9	23	2.32630161961136	1.63315443905142	4.32554406415114	4.44186552957956	-0.11632146542842	0.653308522054441	0.628103698877237	0.183205675857122	0.178049821028857	0.185194683037769	0.454319037311034	NA	NA	0.269509035259503	0.654081154363125	78.487067443769
a5493	loss_cnaOV54	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	10	21	2.30258509299405	NA	1.77122714903054	1.23654773753062	0.534679411499923	1.55624329858495	1.40951596265517	0.367064892337851	0.343570579218618	0.379335478040789	0.454380437124889	NA	NA	0.47487008353415	0.370330732259546	78.487067443769
a5494	gain_cnaOV48_(SOX17)	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	3.70071565498632	4.00872078958098	-0.308005134594661	0.848004538235274	0.755693566311017	0.404102519462261	0.363211658319223	0.407579405628943	0.454650580257795	NA	NA	0.524153378999566	0.598816220016772	78.5017525065433
a5495	loss_cnaOV42	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.48520605015272	3.9461367589825	0.539069291170224	0.663663366337424	1.07657774328427	0.517008096752006	0.812263141998028	0.500724907730033	0.454859878093199	NA	NA	0.103547730995974	0.218790706615343	78.5017525065433
a5496	loss_cnaOV40	287	KIN001-244	PDPK1 (PDK1)	7	25	2.99573227355399	NA	3.29048417768557	3.61546145130415	-0.324977273618579	0.864319700685331	0.909912826813255	0.360693586848065	0.375991977691704	0.357152096379091	0.454881677911958	NA	NA	0.662184899866651	0.405083557158659	78.5017525065433
a5497	gain_cnaOV95_(MECOM)	261	TL-1-85	MAP3K7 (TAK1)	9	23	2.32630161961136	NA	3.34495274757215	3.63802534511793	-0.29307259754578	0.533880462810889	1.07158856579642	0.305866017991887	0.548947972365852	0.273493584105167	0.454963902324017	NA	NA	0.727571468378284	0.313713965514064	78.5017525065433
a5498	KRAS_mut	157	JNK-9L	JNK	3	16	1.63315443905142	NA	-0.177905401337174	-0.00404844677748646	-0.173856954559687	1.26116172825357	0.981702497274191	0.170687715711454	0.137854607117234	0.177097394620489	0.454994252688312	NA	NA	0.187827853226332	0.838346821089619	78.5017525065433
a5499	gain_cnaOV18_(CCNE1)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	2.10066746072985	1.3349204141521	0.765747046577749	0.578067967850078	1.50568268720471	0.524216818064667	1.32466611050198	0.508571329859251	0.45515815115504	NA	NA	0.474885411142331	0.133664016163736	78.5017525065433
a5500	gain_cnaOV19	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	2.10066746072985	1.3349204141521	0.765747046577749	0.578067967850078	1.50568268720471	0.524216818064667	1.32466611050198	0.508571329859251	0.45515815115504	NA	NA	0.474885411142331	0.133664016163736	78.5017525065433
a5501	ARID1A_mut	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	1.36821505607679	1.77333087988694	-0.405115823810145	2.0619315643034	2.42598312711251	0.172726847052447	0.196473942600035	0.166990371566322	0.455200191801026	NA	NA	0.611084508722597	0.728271980951498	78.5017525065433
a5502	loss_cnaOV36	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.73646438820155	2.93467141338105	0.801792974820499	1.27494900493073	1.63996622217105	0.495485890617061	0.628882388016817	0.488908225048108	0.455218316489354	NA	NA	0.662370707648851	0.394682164199681	78.5017525065433
a5503	gain_cnaOV4_(KRAS)	163	JQ1	BRD4	6	13	0.940007258491471	NA	0.622706630793781	-0.15804067222909	0.780747303022871	1.60456997655178	1.94336851431222	0.42198604968306	0.486577285149443	0.401749486663464	0.455360592964522	NA	NA	0.579539028372757	0.375805386203044	78.5017525065433
a5504	loss_cnaOV20	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.31225651007346	5.01566163495113	0.296594875122328	0.508993438058497	0.627076595604462	0.484119087417422	0.582708642087134	0.472980298102865	0.455375541671781	NA	NA	0.109408011406763	0.290316802864831	78.5017525065433
a5505	loss_cnaOV55	272	AR-42	HDAC	7	23	1.63315443905142	NA	-0.253412254819675	0.462035610063755	-0.71544786488343	1.33064241031306	1.94774997191338	0.390296956204119	0.537671022160721	0.367320177230247	0.455611928936386	NA	NA	0.484466405092247	0.286217163168018	78.5098119165704
a5506	loss_cnaOV34	1047	Nutlin-3a	MDM2	5	28	2.07944154167984	1.38629436111989	4.37867416399681	3.6350266492367	0.743647514760103	1.14966362846825	1.59959631549708	0.480112656041374	0.646839211353408	0.464896991544401	0.455618130756688	NA	NA	0.163827662940852	0.251923438337598	78.5098119165704
a5507	loss_cnaOV85	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	7	26	-2.30258509299405	NA	0.00590406369394801	-0.423693384114577	0.429597447808525	1.4830819685557	1.38823332041388	0.305309106721253	0.28966534346506	0.309456228640621	0.455670524589609	NA	NA	0.888607647066875	0.507888006841817	78.5098119165704
a5508	PIK3CA_mut	1046	681640	WEE1, CHEK1	4	7	0.693147180559945	NA	1.73397857244699	2.67628111454139	-0.942302542094406	0.436876594466808	2.02500373931326	0.563397080961109	2.15690781797192	0.465333729415221	0.456095343553594	NA	NA	0.639150214278497	0.275496230041674	78.5687390876627
a5509	loss_cnaOV21, loss_cnaOV22	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	1.67331788519643	0.595062638065451	1.07825524713098	2.50637744928405	2.29210305498653	0.467382684086592	0.430204655503497	0.470421800967983	0.456369683418826	NA	NA	0.945655461611825	0.538821779770031	78.5963524982917
a5510	loss_cnaOV81_(RB1)	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.385773581941866	-0.861470239216009	0.475696657274144	1.48657514575839	0.724072865214896	0.594374088909896	0.319995029266726	0.656973462377937	0.45656223795938	NA	NA	0.0777686747728668	0.636689737028163	78.5963524982917
a5511	gain_cnaOV96	173	FH535	unknown 	4	14	3.46573590279973	NA	2.76034509736601	2.42153532800382	0.338809769362188	1.40212561407027	1.46434931077421	0.233197866743855	0.241640096980075	0.231372232615083	0.456594407530695	NA	NA	0.118857634210707	0.690408328276841	78.5963524982917
a5512	PIK3R1_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	1.75063090102482	1.12060017097875	0.630030730046071	1.27820478785913	1.21904209394277	0.513540984315726	0.492902808712923	0.51682442565076	0.456647473201034	NA	NA	0.265421364570234	0.35037294067052	78.5963524982917
a5513	loss_cnaOV56	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	4.68286244410194	3.77285972385716	0.910002720244779	1.58616429277238	1.47615213133247	0.611980394331975	0.573712776407435	0.616469468782565	0.456881199967028	NA	NA	0.0683785871735421	0.42971075616136	78.5963524982917
a5514	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	333	T0901317	LXR	7	25	2.32630161961136	NA	4.97445547488384	4.69144270883632	0.283012766047523	0.964377259446791	1.15845719090717	0.25216552365222	0.29346685985718	0.244301445291992	0.456936729179056	NA	NA	0.00498266037266583	0.525338317357655	78.5963524982917
a5515	loss_cnaOV70	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	4.76506725202214	3.81017594029941	0.954891311722729	0.401938596595801	1.76333583827115	0.560146840995319	2.37571439968725	0.541525494462216	0.456976951784111	NA	NA	0.145926744576064	0.033568342205255	78.5963524982917
a5516	gain_cnaOV72_(ASXL1)	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-2.80764214187198	-2.00299055598974	-0.804651585882234	1.68369481888037	2.84069392674635	0.301011706632869	0.477908215229477	0.283258811625601	0.457096140159841	NA	NA	0.413997224729996	0.491001173320136	78.5963524982917
a5517	PIK3CA_mut	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	0.395111493467008	0.0199941765654014	0.375117316901606	0.908167383894074	1.44372136434149	0.280535474055087	0.413048655516744	0.259826671660224	0.457224102879328	NA	NA	0.869072384711279	0.51624398880668	78.5963524982917
a5518	loss_cnaOV81_(RB1)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.688501710113961	-0.248450151699231	0.936951861813192	1.42137781345	1.60886528318904	0.586826485407298	0.659185652785029	0.582368127153566	0.457319868888757	NA	NA	0.0994504364640332	0.374053853016694	78.5963524982917
a5519	loss_cnaOV39	1059	AZD8055	MTORC1/2	10	23	0.693147180559945	NA	0.616894044943759	0.135137130578364	0.481756914365395	1.11961943623235	1.12734848398084	0.428186487243715	0.430286308700183	0.427336286171458	0.457328665009175	NA	NA	0.145550185595345	0.272426656654979	78.5963524982917
a5520	gain_cnaOV72_(ASXL1)	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-2.10180801739408	-2.6639472452069	0.562139227812827	2.88236698951848	1.77293090456073	0.279166895640071	0.195026944818965	0.317067758459603	0.457366711862038	NA	NA	0.342191025494633	0.73075781817471	78.5963524982917
a5521	loss_cnaOV35	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.79584358167974	-3.58037741330079	0.784533831621045	2.54574386109774	1.63520785531172	0.44402844995009	0.308174692517081	0.479776212591328	0.457378674009523	NA	NA	0.679483421846585	0.651940968587624	78.5963524982917
a5522	gain_cnaOV18_(CCNE1)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	4.43950819129618	3.97457300025838	0.464935191037795	2.10570357822475	1.41866216349077	0.309630762329993	0.220798024871937	0.327727913666051	0.457415331913543	NA	NA	0.328149246552746	0.694378084313273	78.5963524982917
a5523	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1042	BIRB 0796	p38, JNK2	8	25	2.30258509299405	NA	4.19361175430354	4.46274234394229	-0.269130589638748	0.955004625735419	0.829386633650669	0.313176144193665	0.281810770739984	0.324493521741639	0.457683667070825	NA	NA	0.869104339516872	0.489804971264264	78.6180698498773
a5524	gain_cnaOV26	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-1.59558352204638	-2.7237306363463	1.12814711429991	2.88255995831195	1.82746462806282	0.569489749635031	0.391369869357572	0.617329111040464	0.457707438578023	NA	NA	0.34220366665882	0.572386859779248	78.6180698498773
a5525	loss_cnaOV87, loss_cnaOV88	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.62620853870694	3.95878466752494	-0.332576128818006	1.49549401973121	0.639783767778846	0.456339989312	0.222385462215208	0.519825831112625	0.457831481481196	NA	NA	0.955641562659476	0.73829373170096	78.6251426948072
a5526	loss_cnaOV1	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.752108233937205	0.342656939386167	0.409451294551038	0.579715923865042	0.93020229466423	0.449762026490903	0.706296442266365	0.440174461941997	0.458087248989097	NA	NA	0.909344076853834	0.352783455329196	78.6440084216705
a5527	SMARCA4_mut	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.18366424978029	4.45678841154256	-0.273124161762266	0.895382407157572	0.726941129500981	0.369403506718102	0.305036328141972	0.375717029451554	0.458235638529528	NA	NA	0.522992150150471	0.654448301751033	78.6440084216705
a5528	gain_cnaOV51_(MYC)	134	Etoposide	TOP2	5	14	2.77258872223978	NA	2.68457792286519	2.1400011043113	0.544576818553896	1.0281191917759	2.02064720190069	0.296605082737862	0.529682572711472	0.269506135480577	0.458313521149498	NA	NA	0.406241287059661	0.455106095490811	78.6440084216705
a5529	NF1_mut	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.41694346431396	3.86003587390342	0.556907590410534	0.832460838691274	1.31928413365734	0.434986130035349	0.668989536235792	0.422128619758858	0.458425982360559	NA	NA	0.571924045580376	0.297611707107182	78.6440084216705
a5530	loss_cnaOV16, loss_cnaOV17	262	VX-11e	ERK	6	26	1.63315443905142	NA	3.09904269126921	2.80394717868881	0.295095512580407	1.388753574118	1.06227990243692	0.262703887351249	0.212489471192052	0.277794498327083	0.458612085061477	NA	NA	0.38923441645513	0.641405366341808	78.6440084216705
a5531	loss_cnaOV39	258	STF-62247	stimulates autophagy	9	22	2.32630161961136	NA	4.44793950375509	4.50648707595462	-0.0585475721995223	0.620997406956025	0.703459199572326	0.0858836326549887	0.0942798980216487	0.0832280994194359	0.458660903541952	NA	NA	0.0526586954260547	0.821596448003247	78.6440084216705
a5532	loss_cnaOV57_(ZNRF3)	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	4.18687050113969	3.44347800258125	0.743392498558436	1.2354204771474	1.75008293513572	0.436246432129284	0.601732375583524	0.424775582707333	0.458732047035342	NA	NA	0.697557218068935	0.339063724223467	78.6440084216705
a5533	loss_cnaOV34	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	2.81744313582825	3.01670041392761	-0.199257278099361	1.16209522913298	0.987432769311991	0.196959597303634	0.171463812176584	0.201793260556054	0.459027812536452	NA	NA	0.0867598800789506	0.732719291263951	78.6440084216705
a5534	loss_cnaOV38	1004	Vinblastine	Microtubules	8	23	-2.30258509299405	NA	-2.70772164220719	-3.5264807055449	0.818759063337701	2.26376320867045	1.62573789765297	0.454723671317331	0.36168052391777	0.503623040663392	0.459045908514244	NA	NA	0.138169838695316	0.369214216542705	78.6440084216705
a5535	loss_cnaOV38	1527	GDC0941 (rescreen)	PI3K	7	24	1.38629436111989	NA	0.598386718788948	0.319250498879236	0.279136219909712	0.535524517884655	0.985677889985318	0.306413321903758	0.521238917337179	0.283192128732714	0.459203345313212	NA	NA	0.909348552530856	0.340395994283677	78.6440084216705
a5536	gain_cnaOV18_(CCNE1)	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	4.91176034301272	4.38582409143064	0.525936251582079	0.305955239311666	1.0236644046108	0.538901699354463	1.71899736956727	0.513778001084291	0.459299080912796	NA	NA	0.0307921495029267	0.0490339153003925	78.6440084216705
a5537	loss_cnaOV52, loss_cnaOV53	1042	BIRB 0796	p38, JNK2	9	24	2.30258509299405	NA	4.56655199917439	4.334103526684	0.232448472490389	0.882896689400491	0.85319523106313	0.2699880975908	0.26327935678208	0.272444645759148	0.459413209994875	NA	NA	0.869113631906188	0.507765912826909	78.6440084216705
a5538	loss_cnaOV58	1031	Elesclomol	HSP70	5	26	-1.6094379124341	NA	-3.61406978032901	-4.14548507342977	0.531415293100759	2.00735266353997	1.43178157272604	0.348663751127078	0.264734395083128	0.371156678660818	0.459419259268479	NA	NA	0.863630732899694	0.59740283177544	78.6440084216705
a5539	loss_cnaOV81_(RB1)	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.56394693755186	1.80888225753879	0.755064680013078	1.18946215444958	1.3851808872177	0.552163735958826	0.634795043447582	0.545101861410833	0.459429261437231	NA	NA	0.0337437578754488	0.305634269920097	78.6440084216705
a5540	loss_cnaOV54	274	PXD101, Belinostat	HDAC	9	21	2.99573227355399	NA	0.309172326256942	1.08858581639853	-0.779413490141592	1.34113867377592	2.28700590356936	0.378075613560304	0.581158015484846	0.340800821250679	0.459434837400139	NA	NA	0.41434908508352	0.255743226095023	78.6440084216705
a5541	PTEN_mut	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.49326493885759	3.85842102265241	0.634843916205179	1.61680888714999	1.18127525431101	0.521934288349034	0.392652416281706	0.537422513413655	0.459530072729142	NA	NA	0.697790138915639	0.570009273118686	78.6440084216705
a5542	loss_cnaOV1	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.59242244884441	1.6303961948901	0.96202625395431	1.49807503486022	1.59177521657977	0.60676869117621	0.642174945558767	0.604373182804923	0.459568415702152	NA	NA	0.0405931881195262	0.383935089675646	78.6440084216705
a5543	loss_cnaOV1	333	T0901317	LXR	3	29	2.32630161961136	NA	4.54915276097964	4.77447578490193	-0.225323023922286	0.664510061083575	1.15272257375352	0.199971538849608	0.339081433251538	0.195470297062531	0.459714727534604	NA	NA	0.00498719066597271	0.639393944746061	78.6440084216705
a5544	loss_cnaOV35	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.30140684767955	4.56878877085639	-0.267381923176838	1.64050115176429	0.854126753908032	0.269731184603369	0.162987952120167	0.313047123220809	0.459722502243191	NA	NA	0.324017356895609	0.738322432958437	78.6440084216705
a5545	loss_cnaOV59	1248	FK866	NAMPT	4	28	0	NA	-0.387133454488954	-1.89710407705848	1.50997062256953	3.3647158472443	2.65267899229296	0.552648184806494	0.448766163658722	0.569224782552495	0.459944805672726	NA	NA	0.0439356317749804	0.443850097295495	78.6440084216705
a5546	ARID1A_mut	305	TPCA-1	IKK	8	24	2.99573227355399	NA	3.54379012516691	3.25232997352277	0.291460151644136	1.207236474612	1.24179870367416	0.236225678338031	0.241427556053432	0.23470804952669	0.460121749035713	NA	NA	0.993590912011031	0.567704534939899	78.6440084216705
a5547	TP53_mut	1527	GDC0941 (rescreen)	PI3K	21	10	1.38629436111989	NA	0.469160031147972	0.199835835051689	0.269324196096282	0.876160452070817	0.980043503849189	0.296067869722522	0.30739140925584	0.274808409053775	0.460133853710435	NA	NA	0.909352270673681	0.470186521104062	78.6440084216705
a5548	gain_cnaOV18_(CCNE1)	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	2.76646058443019	2.35983128595288	0.406629298477306	0.287102736997561	0.920353709403169	0.481862181514969	1.41631982589132	0.441818503389308	0.460341318592197	NA	NA	0.619802641374568	0.162285068443543	78.6440084216705
a5549	loss_cnaOV40	328	SNX-2112	HSP90	7	25	0.940007258491471	NA	1.28157198704328	0.532230650007374	0.749341337035911	3.01230604046737	2.09478211298452	0.324719352851061	0.248760028685414	0.357718033007402	0.460449885719053	NA	NA	0.945664960967811	0.554618505811271	78.6440084216705
a5550	loss_cnaOV40	1016	Temsirolimus	MTOR	7	24	-1.6094379124341	NA	-1.42164583385446	-2.20660731590179	0.784961482047325	1.07331548434766	1.63632800763603	0.51075699409745	0.731342735192544	0.479709128233614	0.460525195105663	NA	NA	0.0372547925134624	0.155856465802316	78.6440084216705
a5551	loss_cnaOV20	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.57984048389538	2.94115768252133	0.638682801374051	1.29758675890823	1.16802151411357	0.54030258254707	0.492208167962061	0.546807394946623	0.46058793537787	NA	NA	0.0875544419093975	0.40809280387156	78.6440084216705
a5552	gain_cnaOV49	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.724477101018917	1.40583568218723	-0.68135858116831	0.434907942317753	1.39143439273646	0.505666706894466	1.56667311600968	0.489680709866828	0.460629018566904	NA	NA	0.579595523358361	0.0974694686847403	78.6440084216705
a5553	NF1_mut	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.19178409766961	5.9134897966886	0.278294300981003	0.531563341753309	0.717925041778281	0.396399323701181	0.523539302132981	0.387636988245563	0.460703821756265	NA	NA	0.908416603209299	0.39515369999656	78.6440084216705
a5554	PTEN_mut	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	0.722933924918864	0.302897593457626	0.420036331461238	1.46069194215124	1.70734658823643	0.249500753837759	0.28755983335037	0.246017026862194	0.46086513292748	NA	NA	0.836679262495653	0.62572947631173	78.6440084216705
a5555	loss_cnaOV1	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.68799612030402	2.32266696308644	0.365329157217581	1.00170362700424	0.857520556994577	0.420945143920727	0.364707831107847	0.426029620208734	0.460907947261731	NA	NA	0.649523751000229	0.596972648966681	78.6440084216705
a5556	SMARCA4_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.250600957906541	-0.201532213962722	0.452133171869264	1.48735494692954	1.62536727392997	0.279745981699771	0.30398471649463	0.278172926895503	0.460949404476489	NA	NA	0.0995023295119959	0.659704502256026	78.6440084216705
a5557	KRAS_mut	1133	JNJ-26854165	MDM2	7	26	2.30258509299405	NA	2.77226339818674	3.14743934091889	-0.375175942732152	0.554363492204696	0.979209714601211	0.411128932909273	0.676768849334003	0.38314156522124	0.460988461742127	NA	NA	0.237460555350279	0.203960624428636	78.6440084216705
a5558	loss_cnaOV83	1053	MK-2206	AKT1, AKT2	5	27	1.38629436111989	0.693147180559945	1.81971246979165	1.21548030333991	0.604232166451743	1.07623226371823	1.22568054899916	0.500679655782303	0.561432867998404	0.492976874720853	0.461116485605621	NA	NA	0.0964936080960968	0.302009293243517	78.6440084216705
a5559	gain_cnaOV4_(KRAS)	1529	MLN4924	NEDD8-activating enzyme	5	12	0	NA	0.901150359266691	1.5154344387799	-0.614284079513209	1.49005882808451	1.44876645509434	0.420773658274674	0.412254917681927	0.424004902483202	0.461275053677411	NA	NA	0.855555414690474	0.459307383803129	78.6440084216705
a5560	loss_cnaOV57_(ZNRF3)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	0.687750133684156	1.28892961233767	-0.601179478653516	1.60749107293145	1.1850318403608	0.487866932354951	0.373986200469029	0.507310823370349	0.461493528262877	NA	NA	0.265515196741059	0.516303427639832	78.6440084216705
a5561	loss_cnaOV70	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.68433420082795	2.32819795988285	0.356136240945105	1.03991301472409	0.857975731660634	0.40874704045526	0.342467337077798	0.415088944597296	0.461554951500474	NA	NA	0.606788189327364	0.617738797490314	78.6440084216705
a5562	loss_cnaOV55	1031	Elesclomol	HSP70	7	24	-1.6094379124341	NA	-3.70748308106675	-4.16252413513966	0.455041054072913	2.21293503478803	1.28617151460568	0.298416739840102	0.205627841269411	0.353795002381485	0.461677323952656	NA	NA	0.863644186220237	0.619234923099712	78.6440084216705
a5563	gain_cnaOV95_(MECOM)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	8	25	-1.38629436111989	0.693147180559945	-1.90465453914772	-2.42420660986216	0.519552070714441	1.87044809373441	1.52905018329997	0.322208719032811	0.277768772335798	0.339787455237833	0.461826542705557	NA	NA	0.123230808953738	0.4918134375147	78.6440084216705
a5564	loss_cnaOV20	293	MP470	PDGFR	5	27	2.99573227355399	NA	4.52974669232749	3.96026051184117	0.569486180486323	1.25679224514161	1.83465950831006	0.322006714609232	0.453126746037613	0.310404289137492	0.461862103958101	NA	NA	0.621115947922704	0.417147134931445	78.6440084216705
a5565	gain_cnaOV26	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.968083663821358	0.605891619743213	0.362192044078145	0.128735791586584	0.633277607944151	0.591134575058224	2.81345257301304	0.571932497746055	0.461865145436717	NA	NA	0.0148119346682493	0.0185713205531509	78.6440084216705
a5566	loss_cnaOV57_(ZNRF3)	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	4.06671969250405	3.62641356279093	0.440306129713122	0.987658134677633	1.0577559186424	0.418957498180377	0.445808234907958	0.416264397062643	0.461956268608972	NA	NA	0.830458712115838	0.454429600737662	78.6440084216705
a5567	loss_cnaOV41	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.55200003590657	4.2865383147788	0.265461721127767	0.625761070709699	0.576697295647958	0.454783613208599	0.424222172892119	0.460313795696759	0.462098119310961	NA	NA	0.252515518598436	0.416619648598007	78.6440084216705
a5568	gain_cnaOV49	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	2.3370849004988	2.90952933091171	-0.572444430412906	1.23807692886143	1.05419773703658	0.536276717156802	0.462365800596367	0.543014284988021	0.462267108570828	NA	NA	0.305323099391945	0.511072250229851	78.6440084216705
a5569	loss_cnaOV34	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	2.13715398980881	2.49567019754654	-0.358516207737726	2.572421767783	1.2063780696866	0.244869870878458	0.139369139317581	0.297183956461395	0.462378887330378	NA	NA	0.238685089688816	0.774125134683119	78.6440084216705
a5570	SMAD4_mut	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.18113660006495	2.80776519464256	-0.626628594577604	0.0588380623264673	1.74229339298575	0.372265545610312	10.6500549100463	0.359657332743344	0.462613001750364	NA	NA	0.319823937747097	0.0640776767691843	78.6440084216705
a5571	loss_cnaOV70	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.81695810099416	3.37777124354825	-0.56081314255409	1.24540711552958	1.22797670909379	0.456262273223991	0.450305073386078	0.456696888793562	0.462689153664173	NA	NA	0.993591610846066	0.522682659960965	78.6440084216705
a5572	gain_cnaOV50	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	0.0164186714932781	0.983737630565714	-0.967318959072436	0.627574730215447	2.17622582218646	0.468078286373399	1.54136059420422	0.444493833870864	0.462718643302913	NA	NA	0.414418303368692	0.0851787382960253	78.6440084216705
a5573	gain_cnaOV94	326	GSK690693	AKT	7	25	2.32630161961136	NA	4.65947504991899	4.00981885638226	0.649656193536731	0.837793223876506	1.55865433539419	0.450033579437099	0.775437393168141	0.41680581690515	0.462743629366675	NA	NA	0.0925901994907467	0.16021145537266	78.6440084216705
a5574	gain_cnaOV48_(SOX17)	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-4.22365483918082	-3.6341157345269	-0.58953910465392	1.74910960068025	1.73314453197472	0.339938882050714	0.337050979781164	0.340155765302625	0.462784547238161	NA	NA	0.243695749524622	0.625428453770675	78.6440084216705
a5575	loss_cnaOV38	344	THZ-2-49	CDK9	8	24	2.99573227355399	NA	2.20492471266431	2.71467190977682	-0.509747197112508	3.05327995964811	2.07858183408836	0.217601587169597	0.166950690355711	0.24523797367645	0.462828490877009	NA	NA	0.384512561027318	0.670388525210058	78.6440084216705
a5576	loss_cnaOV34	1026	17-AAG	HSP90	5	28	0	NA	-0.878057136845688	-0.468827697833685	-0.409229439012003	1.16336148468292	2.43505183583235	0.177107197742652	0.351764644437699	0.16805779367408	0.463021034552538	NA	NA	0.0605530816771168	0.566995661701605	78.6440084216705
a5577	PIK3R1_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.11071070089909	-4.14591244814272	1.03520174724362	2.56748234787908	1.66999042912175	0.575441520708972	0.403197220848965	0.619884838374813	0.463137536423775	NA	NA	0.588269818770713	0.562025167855444	78.6440084216705
a5578	gain_cnaOV48_(SOX17)	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.390353323649427	-0.860979552604485	0.470626228955057	1.17614329870966	0.76550123581051	0.587832994402288	0.400143613003092	0.614794865036057	0.463140447337866	NA	NA	0.077850483950989	0.56253744193714	78.6440084216705
a5579	loss_cnaOV40	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	4.521545091362	3.71655868625773	0.80498640510427	1.29752406245623	1.52090619602039	0.543558170573977	0.620401908832752	0.529280771694271	0.463180446397035	NA	NA	0.0684784586262825	0.274543035321923	78.6440084216705
a5580	ARID1A_mut	1264	SGC0946	Q8TEK3 (DOT1L)	9	24	-0.693147180559945	NA	1.81322946694004	2.22859316246541	-0.415363695525365	0.65465780274068	0.479577600604543	0.783228873341503	0.634474520560931	0.866103202071507	0.463247428363856	NA	NA	0.0417520987706719	0.109393862508303	78.6440084216705
a5581	loss_cnaOV84	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	2.72457133631281	2.34574678181785	0.378824554494953	0.873104046906723	0.834367118142611	0.449034873959778	0.433882486098962	0.454026226894292	0.46328398441371	NA	NA	0.619882289173842	0.428104445670372	78.6440084216705
a5582	loss_cnaOV81_(RB1)	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	3.09473139200183	2.17235340048404	0.922377991517793	1.73883423659662	1.7824514182959	0.518691919016736	0.530457689470817	0.517477212590527	0.463362058562154	NA	NA	0.109528764620998	0.37858065881604	78.6440084216705
a5583	loss_cnaOV81_(RB1)	152	CP466722	ATM	4	28	2.77258872223978	NA	2.96242942463917	2.60184343649524	0.360585988143932	0.807195183983358	0.811765788117062	0.444449148450073	0.446714741736326	0.444199538120881	0.46341811668983	NA	NA	0.554704657124832	0.451511316282871	78.6440084216705
a5584	loss_cnaOV102	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.502151271028585	-0.0179762529935895	-0.484175018034995	1.59684211075889	0.898962596418232	0.503624931566579	0.303207821720642	0.538593062674811	0.463510909756331	NA	NA	0.547715893822968	0.653936816791966	78.6440084216705
a5585	loss_cnaOV42	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.74011767450125	3.20991564781937	0.53020202668188	0.902908273986232	1.04769204930705	0.512705316539344	0.587215824638644	0.506066670098872	0.463531175303347	NA	NA	0.090977095494668	0.339391400696905	78.6440084216705
a5586	gain_cnaOV49	1028	VX-702	p38	3	28	0.693147180559945	NA	2.99848081469893	3.36216440809185	-0.363683593392919	0.513963207347784	0.950395203980233	0.392358190897384	0.707606280359335	0.38266564463901	0.463647430770024	NA	NA	0.516757268863185	0.358051822495673	78.6440084216705
a5587	gain_cnaOV50	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.34744553019516	4.50935316808929	-0.161907637894126	0.360630281458617	0.731006629600976	0.230068963959493	0.448957412115448	0.221485868031736	0.463744083734793	NA	NA	0.0806000961078744	0.496010010987488	78.6440084216705
a5588	gain_cnaOV72_(ASXL1)	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	4.37628354623318	3.85223886170027	0.52404468453291	1.46548920063269	1.18640684716721	0.430163316240505	0.357590273818917	0.441707400614025	0.463785589710347	NA	NA	0.697843762049776	0.536046343883396	78.6440084216705
a5589	loss_cnaOV16, loss_cnaOV17	223	ZSTK474	PI3K	6	26	1.63315443905142	2.32630161961136	1.06469633411318	0.687549333349044	0.377147000764135	0.705567726620994	1.10105629131593	0.360705322482754	0.534529835385632	0.342531988363089	0.463814477435119	NA	NA	0.771248605598162	0.316373812880267	78.6440084216705
a5590	loss_cnaOV85	1239	YK 4-279	RNA helicase A	5	19	2.30258509299405	NA	1.99059992184626	1.4586957906406	0.531904131205654	0.960692109950472	1.06068066224724	0.509870585546371	0.553667637837763	0.501474336374458	0.463909162347485	NA	NA	0.284986525344091	0.317979814565562	78.6440084216705
a5591	loss_cnaOV85	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	0	NA	-2.6463715714883	-1.8130342482656	-0.833337323222703	2.67401059519599	1.82775692061459	0.412662354873427	0.311643239080593	0.455934437355318	0.463927598959526	NA	NA	0.27691931431942	0.46067190638273	78.6440084216705
a5592	loss_cnaOV42	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.00056169171607758	0.423179783195574	-0.422618091479496	0.755109533768447	0.920236166339127	0.464512062781146	0.559677864707097	0.459249600198556	0.46394440179844	NA	NA	0.909367371716692	0.441331722013097	78.6440084216705
a5593	NF1_mut	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	1.54402743965365	2.38624360080793	-0.842216161154278	2.39117242910626	1.70476717575616	0.472416971977633	0.352218916085892	0.494035885446179	0.463966736568288	NA	NA	0.109537133656255	0.539011329786174	78.6440084216705
a5594	loss_cnaOV55	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	1.88707433116451	2.41246211030544	-0.525387779140928	0.502670450513016	1.55642363199072	0.373987884337264	1.04519328439682	0.337560911015557	0.464007704827951	NA	NA	0.528626279784733	0.166682928119951	78.6440084216705
a5595	MLL2_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	2.5249723334395	2.66812367209578	-0.143151338656277	0.124703927224826	1.77426587312492	0.0834035614082606	1.14792967504698	0.0806820109796466	0.464233186920673	NA	NA	0.639055373412936	0.669187360714687	78.6440084216705
a5596	NF1_mut	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.15284155707596	3.52716139864652	-0.374319841570553	0.863528581153553	0.907930788264294	0.414194719145886	0.433477072722381	0.412277947183778	0.464262832905522	NA	NA	0.793621415566522	0.464892669834184	78.6440084216705
a5597	KRAS_mut	193	GW-2580	CSF1R (cFMS)	7	25	2.99573227355399	NA	5.51515994684447	5.78564238979038	-0.270482442945909	0.432924434517547	0.632982717370759	0.452049924189851	0.624779803078881	0.427314104355678	0.464281674670973	NA	NA	0.191032622751303	0.212034576371584	78.6440084216705
a5598	loss_cnaOV85	1006	Cytarabine	DNA synthesis	7	24	0.693147180559945	NA	0.225327109364511	-0.209494918943675	0.434822028308186	1.30121705960811	1.24442981675365	0.346088554851987	0.334165637544855	0.349414665619719	0.464314483221614	NA	NA	0.766420107649466	0.451382758120475	78.6440084216705
a5599	gain_cnaOV72_(ASXL1)	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.22483201088309	4.46939617146887	-0.244564160585778	0.357419953425828	0.780515567815281	0.331276315281589	0.684248761832292	0.313336684968796	0.464355762326449	NA	NA	0.523099448358961	0.285575518022392	78.6440084216705
a5600	loss_cnaOV54	309	Y-39983	ROCK	10	22	2.99573227355399	NA	5.27258260560912	4.82415641011282	0.448426195496304	1.37878310118372	1.15873217643766	0.364902914247908	0.325233312702571	0.386997275655985	0.46442822020542	NA	NA	0.371155631513274	0.384976133533597	78.6440084216705
a5601	RB1_mut	1028	VX-702	p38	3	28	0.693147180559945	NA	2.89990188450668	3.37272643632673	-0.472824551820055	1.58602268225646	0.852833456165863	0.512655727397154	0.298119665695676	0.554416045010431	0.464476185853118	NA	NA	0.516772308644377	0.658969234515239	78.6440084216705
a5602	loss_cnaOV55	1375	Temozolomide	DNA akylating agent	8	25	3.40119738166216	NA	6.11124199749101	5.89473618058879	0.216505816902218	0.615609245884776	0.724990366207193	0.30850813692057	0.351693575672418	0.298632681196681	0.464484578151431	NA	NA	0.908430687030596	0.421840439969549	78.6440084216705
a5603	loss_cnaOV81_(RB1)	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.37987614396869	2.07882056985364	0.301055574115058	0.330457203067202	0.573260104390932	0.543000304391956	0.911027422978691	0.525164008116209	0.464707616462836	NA	NA	0.041763430123257	0.177322273594399	78.6440084216705
a5604	loss_cnaOV70	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.62166801871577	2.25887665580627	0.362791362909499	0.425155510438667	0.927076474207436	0.402440525464266	0.853314502580899	0.391328410333843	0.464904088432675	NA	NA	0.593247788228124	0.288789220682281	78.6440084216705
a5605	PIK3CA_mut	1013	Nilotinib	ABL	5	16	0.693147180559945	NA	3.27796283312783	3.24036914336491	0.0375936897629159	0.922064861358519	1.07243813572609	0.0360581693702222	0.0407711987934639	0.0350544134067586	0.465026491239279	NA	NA	0.56358681153734	0.94101675624214	78.6440084216705
a5606	KRAS_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	6	17	2.30258509299405	NA	1.19515435068752	1.69301616835697	-0.49786181766945	0.805240893972749	1.1281270653697	0.469589468562593	0.618276867700039	0.441317146758016	0.46505106182266	NA	NA	0.452129636891571	0.266219723979897	78.6440084216705
a5607	gain_cnaOV18_(CCNE1)	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	5.03974381036123	4.76011739680326	0.279626413557971	0.488135212162487	0.679511548047903	0.421845221422671	0.572846224961315	0.411510907152764	0.465092693103391	NA	NA	0.761398409108142	0.358506682397156	78.6440084216705
a5608	loss_cnaOV43_(NF1)	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.64414113103801	3.23916342580612	0.404977705231889	0.621694313662275	1.16245693660744	0.366249659100301	0.651409698194354	0.348380823821133	0.465619246504651	NA	NA	0.950779003851053	0.282411773984093	78.6440084216705
a5609	gain_cnaOV95_(MECOM)	333	T0901317	LXR	9	23	2.32630161961136	NA	4.98307651261928	4.66345945354441	0.319617059074871	0.724187506174854	1.23159772091812	0.285623311156764	0.44134572379339	0.259514168990672	0.465738895531499	NA	NA	0.00499687841461702	0.373216368694435	78.6440084216705
a5610	gain_cnaOV94	163	JQ1	BRD4	3	16	0.940007258491471	NA	0.746511351925034	-0.0348639381244121	0.781375290049446	1.79017173233814	1.87517045382437	0.418884512195208	0.436480632519481	0.416695606767826	0.465829282858817	NA	NA	0.57984663338528	0.54230702862137	78.6440084216705
a5611	loss_cnaOV1	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.63681258470978	1.8267645154901	0.810048069219686	0.893113548073754	1.39689284645021	0.59127909937247	0.906993372753978	0.579892775081628	0.46594743729425	NA	NA	0.0337877120780068	0.251451295897231	78.6440084216705
a5612	loss_cnaOV1	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.34676564951075	4.86424807466653	0.482517574844219	0.323080651012075	0.881504538680269	0.564489262308009	1.49348954613251	0.547379569442277	0.466058055604051	NA	NA	0.153007880079018	0.100585060558771	78.6440084216705
a5613	SMARCA4_mut	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-3.5235160977115	-2.65032091791181	-0.87319517979969	1.00223142285851	1.8059633778449	0.495061216515692	0.871251050290573	0.48350658186751	0.466117934674461	NA	NA	0.695411855688947	0.270043499320323	78.6440084216705
a5614	loss_cnaOV55	274	PXD101, Belinostat	HDAC	7	23	2.99573227355399	NA	0.232892309295449	1.04402638763537	-0.811134078339922	1.44496968165805	2.20294988884812	0.392973729923674	0.561350240517972	0.368203599385571	0.466232797075559	NA	NA	0.414491512686246	0.273084835433532	78.6440084216705
a5615	gain_cnaOV96	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.688460638245747	0.336921350060789	0.351539288184957	1.40313548668564	0.835555456484672	0.385957964273499	0.250538377455858	0.420725261808408	0.466317428464482	NA	NA	0.909376675191612	0.655701424433606	78.6440084216705
a5616	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.60883185307444	0.941627323615341	0.667204529459103	1.22953628932012	1.56941845440306	0.430709782921151	0.542647285203787	0.425128510237175	0.466533659637281	NA	NA	0.790402489385896	0.45437112609463	78.6440084216705
a5617	loss_cnaOV58	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.398461375152176	-0.0013132694125544	-0.397148105739622	1.25001278747825	0.908281589447467	0.413311263272383	0.317715234370377	0.437252180770523	0.466543290028853	NA	NA	0.547766499591178	0.528950961696908	78.6440084216705
a5618	gain_cnaOV4_(KRAS)	190	Bleomycin	DNA damage	6	13	4.15888308335967	NA	2.31308232369044	1.36840105051219	0.944681273178255	1.17474865203333	2.63876892248566	0.409531906101554	0.804156081850478	0.35800075752309	0.466641797490546	NA	NA	0.61140075122744	0.295388531325232	78.6440084216705
a5619	gain_cnaOV94	238	CAL-101	PI3Kdelta	7	25	2.99573227355399	2.32630161961136	4.67141686620183	4.3076475355519	0.363769330649937	0.899738321014668	1.00071277767401	0.3706827841318	0.404305698838859	0.363510228674665	0.46668432037098	NA	NA	0.510242748695779	0.377171292409715	78.6440084216705
a5620	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.29879877561345	3.63457516036165	0.664223615251802	1.71319797896849	1.17662094493197	0.545164650603734	0.387709782176914	0.564517925771081	0.466689756967692	NA	NA	0.196925181994631	0.5738423661492	78.6440084216705
a5621	gain_cnaOV96	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.82362023124233	3.50596505591297	0.317655175329363	0.626477006061123	1.00197683464317	0.330742559603636	0.507050015014231	0.317028462481857	0.46679141172555	NA	NA	0.727702818542504	0.376397387844815	78.6440084216705
a5622	loss_cnaOV84	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	5.37282332842151	4.54205497590804	0.830768352513475	1.96220910407448	1.38960810443557	0.538213256579974	0.423384210575929	0.597843629338156	0.46681720246952	NA	NA	0.119719524740192	0.419671989230437	78.6440084216705
a5623	gain_cnaOV18_(CCNE1)	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.43227995086376	3.65327576535023	0.779004185513526	1.09484680568173	1.59226828607977	0.502221090557837	0.711518891474923	0.489241789416951	0.466848327838658	NA	NA	0.164015811093911	0.266335909585312	78.6440084216705
a5624	loss_cnaOV36	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.26998060610605	3.72401781758083	-0.454037211474779	0.965542636908453	1.05878668473482	0.431255137691276	0.470240457664872	0.428827844192709	0.466848482091311	NA	NA	0.830493019571705	0.50777967294684	78.6440084216705
a5625	NF1_mut	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.62233996110208	1.26525609624027	0.357083864861809	0.542691495807618	1.27516366674799	0.292251257373269	0.657986844496995	0.28002983003152	0.466850175982624	NA	NA	0.0965702916668958	0.350909508647442	78.6440084216705
a5626	PTEN_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	0.113338316991293	-0.394070786520225	0.507409103511518	0.556029782958234	1.47069343847942	0.360277835473165	0.912557418798611	0.345013508754169	0.466857613057622	NA	NA	0.888658448533862	0.220668248162279	78.6440084216705
a5627	loss_cnaOV39	1495	AZD-2281	PARP1, PARP2	10	23	2.30258509299405	NA	3.49306660517447	3.59087537063502	-0.0978087654605524	1.15499911719979	0.809845409389783	0.105918008950488	0.084682978544332	0.120774612446406	0.46687796402149	NA	NA	0.141811025363833	0.811740125435518	78.6440084216705
a5628	loss_cnaOV35	1033	Vismodegib	SMO	5	26	2.30258509299405	NA	4.758546047811	4.94025049231308	-0.181704444502079	1.33074132552129	0.764147854582984	0.210145212925866	0.136543775275709	0.237787024346538	0.466886042351252	NA	NA	0.153022059894079	0.780282862418952	78.6440084216705
a5629	gain_cnaOV96	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	4.06267721612796	3.62699105941609	0.435686156711873	0.467175535989115	1.09704478948404	0.41447294842678	0.932596258041269	0.397145276918714	0.466940676719638	NA	NA	0.830493660518609	0.196595856609276	78.6440084216705
a5630	gain_cnaOV94	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-1.61175259415791	-2.72069893532538	1.10894634116747	2.76446189604916	1.85358615222184	0.559342451300006	0.401143652134371	0.59827073040992	0.467053333747457	NA	NA	0.342544680114586	0.564198030778472	78.6440084216705
a5631	loss_cnaOV83	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.55001338420534	4.28692036318288	0.263093021022455	0.510535379001265	0.594759336831134	0.450605903179307	0.51532769685253	0.442352065331517	0.467230519675179	NA	NA	0.252619028194246	0.342642704489313	78.6440084216705
a5632	gain_cnaOV96	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	5.11702333283679	4.81247880073884	0.304544532097949	0.683749899860082	0.603723156366847	0.495198101508736	0.44540340285281	0.504444013595024	0.467322584941363	NA	NA	0.0490337804535803	0.392860281677988	78.6440084216705
a5633	gain_cnaOV49	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.20447460319998	4.56065653375923	-0.356181930559248	0.69607786681381	1.00773922747184	0.359563455751035	0.511698399763256	0.353446527483919	0.467332652126061	NA	NA	0.324164918607253	0.480804221056056	78.6440084216705
a5634	gain_cnaOV18_(CCNE1)	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	1.94655636590003	2.34545647981936	-0.39890011391933	1.81522328421707	0.720160294396386	0.444363488108085	0.219752642767239	0.553904619600938	0.467381646368146	NA	NA	0.593287229653865	0.692072381034348	78.6440084216705
a5635	KRAS_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	7	24	0.693147180559945	NA	-0.694134865172163	-0.00133979420964416	-0.692795070962518	1.86507127533601	1.51564930448715	0.434561500105302	0.371457691791272	0.457094572544894	0.467554361312219	NA	NA	0.0995951522799238	0.393075830347587	78.6440084216705
a5636	loss_cnaOV82	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.8135340765668	4.35560959550955	0.457924481057244	0.870738457036467	0.757362698308849	0.598030581888595	0.525903590632458	0.604630360169263	0.467568567878937	NA	NA	0.0425020927060403	0.461678109829088	78.6440084216705
a5637	gain_cnaOV95_(MECOM)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	23	3.68887945411394	NA	3.23539591543878	3.5780334539526	-0.342637538513817	1.02871188662774	1.13806232793486	0.307946783031292	0.333074345662546	0.301070978366862	0.467670012448319	NA	NA	0.726007775610887	0.443801043152204	78.6440084216705
a5638	loss_cnaOV54	166	FTI-277	Farnesyl transferase (FNTA)	6	13	0.0237165266173161	NA	2.69169012342172	2.33178237588336	0.359907747538361	0.691453417349634	0.899344126228335	0.426665956107363	0.520509029976163	0.400189134550465	0.467673439318155	NA	NA	0.619999584998116	0.357272446792811	78.6440084216705
a5639	loss_cnaOV55	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	7.07084961016047	6.59811967436172	0.472729935798759	1.20736812290423	1.58098855318922	0.310651767680711	0.391537532614032	0.299009081909641	0.46773153802104	NA	NA	0.334437602561623	0.540185956860094	78.6440084216705
a5640	ARID1A_mut	211	TL-2-105	CRAF	8	24	2.32630161961136	1.63315443905142	4.37443488804753	4.42072186055457	-0.0462869725070414	0.463475389054316	0.680946128713554	0.0726777057376421	0.0998693212200247	0.0679744998249522	0.467742975516305	NA	NA	0.269776726896502	0.831883462776931	78.6440084216705
a5641	gain_cnaOV94	230	GSK429286A	ROCK2	7	25	2.99573227355399	2.32630161961136	5.84282892088838	5.45360252457887	0.38922639630951	0.776499010479011	1.01797477838113	0.399420216744196	0.501258071236177	0.382353673760455	0.467877232971035	NA	NA	0.302809558224904	0.296505990257216	78.6440084216705
a5642	gain_cnaOV50	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	-1.83841021609924	-0.948133647703597	-0.890276568395648	0.778405561685238	2.05623317369361	0.452794280846689	1.14371814927454	0.432964792021347	0.467965079242041	NA	NA	0.442279419173677	0.134381690773012	78.6440084216705
a5643	NF1_mut	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-4.04188930338618	-3.20752859820909	-0.834360705177092	1.12663917281898	1.87867144459262	0.459606684952235	0.740574911033338	0.444122737681798	0.468095434511164	NA	NA	0.138319665922883	0.260049002827202	78.6440084216705
a5644	gain_cnaOV49	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.59710411942435	2.22780187165832	-0.630697752233973	0.623574385184468	1.33537860206185	0.485573065218818	1.01142344396875	0.472298830653841	0.468112333986719	NA	NA	0.685641841680841	0.218926871722965	78.6440084216705
a5645	gain_cnaOV19	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.67915174899074	2.32873407559014	0.350417673400599	0.815005175637395	0.875393427877041	0.402086727810206	0.429957605025694	0.400297354585371	0.468134298987293	NA	NA	0.606887059376304	0.541279514869273	78.6440084216705
a5646	PTEN_mut	326	GSK690693	AKT	3	29	2.32630161961136	NA	3.92609795232263	4.17529320351798	-0.249195251195359	0.770933427193106	1.50555710978863	0.169744157692234	0.323238352892097	0.165516970146914	0.468202910738111	NA	NA	0.0926612310446133	0.661080911701636	78.6440084216705
a5647	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	260	NG-25	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.28717305909698	2.93492816215081	0.352244896946177	1.43304728164715	0.972464266678543	0.32603051336814	0.245801308482512	0.362218858847401	0.4682997025283	NA	NA	0.433221090149486	0.55832056511527	78.6440084216705
a5648	gain_cnaOV96	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.13365965341771	3.80106117018193	0.332598483235773	0.6749851867178	0.882359981952791	0.384743393888384	0.492749307363432	0.376941939841474	0.468386866981146	NA	NA	0.923533208687628	0.419675107436938	78.6440084216705
a5649	loss_cnaOV57_(ZNRF3)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	3.35378991746369	2.74607643837992	0.607713479083766	1.94944528255758	1.51181877926633	0.38967331755579	0.311736617858016	0.401975082872488	0.468468377927456	NA	NA	0.96872486127842	0.585534878591538	78.6440084216705
a5650	gain_cnaOV51_(MYC)	279	BIX02189	MAP2K5 (MEK5)	8	24	2.99573227355399	NA	4.56245084162861	4.38742708129359	0.175023760335022	0.537874634624024	0.791082939210366	0.236584527312447	0.32539879940121	0.221245777983438	0.468468430703285	NA	NA	0.523170285002063	0.491974029458551	78.6440084216705
a5651	loss_cnaOV58	1005	Cisplatin	DNA crosslinker	5	26	1.79175946922805	2.30258509299405	3.52386920903547	2.92735666609539	0.596512542940083	1.18951049959795	1.17968692571056	0.505071063650116	0.501477324615211	0.50565326269153	0.468529074555676	NA	NA	0.0876584158123491	0.345987576451117	78.6440084216705
a5652	gain_cnaOV96	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	3.73152204248135	3.2096932212214	0.521828821259952	0.687618052642389	1.01508403267189	0.540530478466637	0.758893428197036	0.514074504636231	0.468601044805253	NA	NA	0.187651647236218	0.266645893605209	78.6440084216705
a5653	loss_cnaOV20	172	Embelin	XIAP	4	15	3.46573590279973	NA	2.7472298022673	3.19151578955021	-0.444285987282909	1.03808274096529	0.93132187288796	0.467161342014287	0.427987066685819	0.477048805806752	0.468690230367413	NA	NA	0.669263566052591	0.47714831507368	78.6440084216705
a5654	gain_cnaOV96	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	3.3618276569286	2.63553563556245	0.72629202136615	2.2165814795832	1.57128766467177	0.434442212036761	0.327663128134916	0.462227278744575	0.468765611701925	NA	NA	0.319946420522574	0.516109595468074	78.6440084216705
a5655	ARID1A_mut	299	OSI-027	MTORC1/2	8	24	2.99573227355399	NA	1.30927241010743	1.60497937022343	-0.295706960116	1.92470813567386	1.93179305487363	0.153204750940612	0.153637299409279	0.15307382919199	0.468848176672853	NA	NA	0.781993713708014	0.713448960443572	78.6440084216705
a5656	PIK3R1_mut	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-4.51169795187776	-3.9928210741966	-0.518876877681166	0.744688717546058	1.59265659023122	0.339816635328594	0.696770161082874	0.325793319704805	0.468860850288847	NA	NA	0.863686288317588	0.313275724338553	78.6440084216705
a5657	PTEN_mut	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.46824000746696	4.67999913476002	0.788240872706934	0.350102883031235	1.25534859087023	0.648879783602612	2.25145496055972	0.627905968461326	0.468916277854482	NA	NA	0.423513092778919	0.03010570887343	78.6440084216705
a5658	loss_cnaOV54	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	6	13	2.07944154167984	NA	3.213352764341	3.58016980199217	-0.366817037651176	0.625227577501304	1.26058130661157	0.329855099257699	0.58669363100896	0.290990383347169	0.468965082141797	NA	NA	0.771848332407844	0.40871461524031	78.6440084216705
a5659	gain_cnaOV51_(MYC)	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	3.59066747555682	4.0158712967476	-0.425203821190783	1.11244768774834	1.24396400845822	0.349123098719799	0.382223654985	0.341813604171543	0.469123556563668	NA	NA	0.697909913728764	0.405496817249505	78.656682244368
a5660	loss_cnaOV40	192	LFM-A13	BTK	4	15	2.77258872223978	NA	4.95804283352674	4.66296324453771	0.29507958898903	0.635923696946798	0.698972935078271	0.428728735551723	0.464017287617632	0.422161680632151	0.469308000434313	NA	NA	0.956681770293945	0.45538967800484	78.6737050468622
a5661	loss_cnaOV41	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.0615632693760576	0.42979503433778	-0.368231764961723	0.628499569265321	0.937087355742383	0.404636932792147	0.585890242362718	0.392953509302237	0.469493756879707	NA	NA	0.909389008530662	0.354118602964986	78.6895115491994
a5662	gain_cnaOV94	1032	Afatinib	ERBB2, EGFR	7	24	-0.693147180559945	NA	0.788028381792562	0.231407168770142	0.55662121302242	1.61038919880472	1.68841554317484	0.332793806341626	0.345643906103916	0.329670746797183	0.469738507199761	NA	NA	0.83674126041328	0.444304144124582	78.6895115491994
a5663	loss_cnaOV33_(ZFHX3)	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.42890149142261	3.65374175975591	0.7751597316667	1.32116743148934	1.57400233041938	0.49967223799278	0.586723312421403	0.492476864033719	0.469754175092883	NA	NA	0.16406333692153	0.340064988803707	78.6895115491994
a5664	PIK3CA_mut	185	OSI-906	IGF1R	5	13	0.940007258491471	NA	2.63778524733838	2.04283254128295	0.594952706055427	0.94687676202571	1.39149989161487	0.459515718520744	0.628331721630393	0.427562164855773	0.469809204634937	NA	NA	0.684217989197213	0.321564003594919	78.6895115491994
a5665	loss_cnaOV83	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.46001116582266	2.9332158134967	-0.473204647674042	0.373030804629254	1.1893338036218	0.424187039446224	1.26854040417479	0.397873705626649	0.469816956442388	NA	NA	0.389455056123882	0.109262742696736	78.6895115491994
a5666	loss_cnaOV39	303	PIK-93	PI4K, PI3K	9	23	2.99573227355399	NA	2.55544859668917	3.04223027923172	-0.486781682542551	0.585610256395512	1.40131518077219	0.393348744093777	0.831238314606612	0.347374872706591	0.46999862048468	NA	NA	0.230320001528442	0.176277415117907	78.7021070222364
a5667	gain_cnaOV4_(KRAS)	310	YM201636	FYV1	8	24	1.63315443905142	NA	2.55380434203506	2.29128731475577	0.262517027279288	0.847123352636469	0.872837067050594	0.302820838725082	0.30989232732431	0.300762922645299	0.470083234395401	NA	NA	0.649648942661686	0.465379234814099	78.7021070222364
a5668	loss_cnaOV40	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	4.2757951470176	3.96462042973185	0.311174717285751	1.60863293123319	1.47680772513833	0.206884692705295	0.193440474358064	0.210707671681907	0.470221798873294	NA	NA	0.328405881100904	0.656137058455676	78.7021070222364
a5669	gain_cnaOV51_(MYC)	304	SB52334	ALK5	8	24	2.99573227355399	NA	4.53169651524598	4.31162179674223	0.220074718503754	0.67171800418796	1.16049057212855	0.206319792700335	0.327629626021119	0.1896393850922	0.470289615383906	NA	NA	0.350489492652967	0.518754291506613	78.7021070222364
a5670	gain_cnaOV49	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.70576066311614	4.87602628602704	-0.170265622910909	0.339922557457532	0.638859035248545	0.273121709513129	0.500895333879633	0.266515167692147	0.470502626251621	NA	NA	0.0490616482523742	0.50223394451057	78.7021070222364
a5671	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	8	25	0.693147180559945	NA	3.01800450703868	2.72742198673011	0.290582520308564	0.950377328141399	0.964673747559361	0.302229192634717	0.305754895139219	0.301223622021168	0.470578765515851	NA	NA	0.966102637101431	0.467729108963276	78.7021070222364
a5672	ARID1A_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	1.38629436111989	0.693147180559945	2.5938412503674	2.90445021373191	-0.310608963364516	1.08261743527628	1.70278447014302	0.198291494666787	0.286905561691098	0.182412377379991	0.470752287928312	NA	NA	0.968727709218032	0.54143002039021	78.7021070222364
a5673	loss_cnaOV85	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	7	26	1.6094379124341	NA	2.84826071104969	2.20812151702552	0.640139194024171	1.82450527838151	1.46647144694393	0.415063324465761	0.350856312453109	0.436516643647031	0.470795370625178	NA	NA	0.240922397817188	0.41588856462079	78.7021070222364
a5674	gain_cnaOV48_(SOX17)	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	4.88888011571886	5.07991401196176	-0.191033896242899	0.242508435449024	0.638481103348831	0.308118545924696	0.787741242440432	0.299200548365374	0.470866805743629	NA	NA	0.109630037551428	0.339987360502523	78.7021070222364
a5675	SMARCA4_mut	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	2.28295857853032	3.08503408334704	-0.802075504816723	1.56096744686968	1.62219226763767	0.495664373023857	0.513832307281733	0.494439235605993	0.470952975325405	NA	NA	0.662580421152297	0.47248742419741	78.7021070222364
a5676	RB1_mut	1248	FK866	NAMPT	3	29	0	NA	-1.14719612312962	-1.76640895193809	0.619212828808471	1.0827311522136	2.85699633936509	0.223200706977145	0.571898968218023	0.216735604549664	0.471232081940055	NA	NA	0.0440287598445799	0.480103540493174	78.7021070222364
a5677	loss_cnaOV82	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	-0.0967527742872788	0.960485607538649	-1.05723838182593	0.291080136570403	2.14509201133879	0.51110718350228	3.63212136108853	0.492863884736621	0.47128711829881	NA	NA	0.41459526522446	0.0253680500038403	78.7021070222364
a5678	BRCA1_mut	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.6137289012108	-0.845317475519654	0.231588574308854	0.806141929516965	0.809846424359963	0.286101145996417	0.287280149846096	0.285966039168331	0.471334470431906	NA	NA	0.0779499010910131	0.620755968001823	78.7021070222364
a5679	gain_cnaOV50	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	3.38248136696294	3.95941207846069	-0.576930711497756	0.832443375075397	1.65700273426993	0.362476180685899	0.693057003961983	0.348177283939095	0.471338085777652	NA	NA	0.714823287840697	0.306309673043416	78.7021070222364
a5680	loss_cnaOV39	312	AV-951	VEGFR	9	23	-2.05572501506252	NA	0.851284022208999	0.557110946266794	0.294173075942206	0.696071604354372	0.571402492695846	0.484510070021587	0.422618986469158	0.514826378433026	0.471453156637083	NA	NA	0.0148480198694398	0.280634120595808	78.7021070222364
a5681	SMAD4_mut	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.52550205992063	3.84604735573686	0.679454704183768	2.0930242066881	1.46378066441582	0.438042623432549	0.32462821118486	0.464177947353151	0.471486146204931	NA	NA	0.74180137492041	0.636615018363328	78.7021070222364
a5682	ARID1A_mut	300	CX-5461	RNA Pol I	8	23	2.32630161961136	NA	3.11249376066889	3.68788860821311	-0.575394847544214	1.3945375772428	1.79086542978286	0.337739903226979	0.412606197878046	0.321294296028698	0.471635802623741	NA	NA	0.697717954861045	0.36630049930832	78.7021070222364
a5683	PIK3CA_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	2.35502777393119	2.4147087628135	-0.059680988882302	0.761986994460993	1.06042282875191	0.0597849076415794	0.0783228445053955	0.0562803697394416	0.471782762013299	NA	NA	0.407786342576311	0.895564000816187	78.7021070222364
a5684	gain_cnaOV51_(MYC)	305	TPCA-1	IKK	8	24	2.99573227355399	NA	3.59694021498566	3.23461327691652	0.362326938069143	1.30445934112904	1.20650630839944	0.294560400436745	0.277760238778728	0.30031085253902	0.47180382619215	NA	NA	0.993594042015184	0.502321715681044	78.7021070222364
a5685	loss_cnaOV55	330	XMD13-2	RIPK	7	25	2.32630161961136	NA	4.37297101235238	4.00311652937034	0.369854482982039	0.725523670532262	1.19667584471501	0.330688432794464	0.509775901192452	0.309068228138356	0.471850515964024	NA	NA	0.819147702899302	0.324438387375478	78.7021070222364
a5686	gain_cnaOV95_(MECOM)	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	-0.143136063496778	-0.702601811691824	0.559465748195046	1.99381049627871	1.28919170564055	0.376651715642428	0.280601265385674	0.433966295119057	0.471864777782595	NA	NA	0.908733724561593	0.582633082395249	78.7021070222364
a5687	loss_cnaOV84	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	3.23319573721007	2.83618470941432	0.397011027795747	0.912641701875253	0.828574679899018	0.469706391896132	0.435013025352653	0.47914936025336	0.47201250545857	NA	NA	0.328026172217435	0.414170714941679	78.7021070222364
a5688	loss_cnaOV85	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	3.23319573721007	2.83618470941432	0.397011027795747	0.912641701875253	0.828574679899018	0.469706391896132	0.435013025352653	0.47914936025336	0.47201250545857	NA	NA	0.328026172217435	0.414170714941679	78.7021070222364
a5689	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	4.4009571502663	3.78574099365227	0.615216156614035	1.74450931847925	1.56032211556513	0.387660158709919	0.352658567138145	0.394287916883886	0.47204614371761	NA	NA	0.714831472450845	0.49402466760972	78.7021070222364
a5690	gain_cnaOV4_(KRAS)	1052	RO-3306	CDK1	7	26	1.6094379124341	NA	3.25843234353236	3.54192386093563	-0.283491517403273	0.847588367804595	0.917766190091866	0.313385908070912	0.334468390756195	0.308892962569144	0.472100576390104	NA	NA	0.793684716083168	0.458010654445848	78.7021070222364
a5691	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	295	NVP-BHG712	EPHB4	7	25	2.32630161961136	NA	3.5233348001761	3.17491234649726	0.348422453678835	1.35651055924851	1.00673555698385	0.320906998395944	0.256852002591013	0.346091335765172	0.472336946688308	NA	NA	0.0617118695761345	0.544801865781574	78.7021070222364
a5692	loss_cnaOV84	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	6	27	1.6094379124341	NA	2.88575612147699	2.22349806263517	0.662258058841823	1.99568880446433	1.44021155233255	0.429094074598434	0.331844352366141	0.459833874939579	0.472348408474412	NA	NA	0.240950687244116	0.469831586758583	78.7021070222364
a5693	loss_cnaOV84	219	AT-7519	CDK9	6	26	2.32630161961136	NA	1.16550397421479	1.57437010571782	-0.408866131503021	1.02704279704873	1.81697251820499	0.238986138342515	0.398100383623665	0.225026040518733	0.472403236817241	NA	NA	0.314826381568432	0.470250717720169	78.7021070222364
a5694	loss_cnaOV36	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	1.0581405147093	0.281983899246552	0.776156615462749	1.54844121775707	1.68191539705598	0.463916562117387	0.501250293883946	0.461471853353224	0.472536359201236	NA	NA	0.836760416082911	0.48312860408946	78.7021070222364
a5695	loss_cnaOV84	1194	SB-505124	TGFR1 (ALK5)	6	26	2.30258509299405	NA	4.83467404089467	4.53161330499911	0.303060735895563	0.915016141996087	0.950149113539618	0.320908244414229	0.331208075995733	0.318961236270128	0.472536373091539	NA	NA	0.942987297269336	0.489319331840457	78.7021070222364
a5696	loss_cnaOV38	206	Ruxolitinib	JAK1, JAK2, TYK2	8	24	1.65632149833295	0.0237165266173161	4.6075598739166	4.40005882661238	0.207501047304226	0.790936095897901	0.457106974362821	0.37501205681492	0.262348688320594	0.453944172681832	0.472580278181439	NA	NA	0.363574599889907	0.500089779135384	78.7021070222364
a5697	loss_cnaOV16, loss_cnaOV17	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.15188892955002	3.69749310327746	-0.545604173727444	1.22343511411071	0.850785847023478	0.609572795311029	0.445960858434271	0.64129436994782	0.472878233406664	NA	NA	0.0588407545743565	0.524788058373477	78.7021070222364
a5698	loss_cnaOV41	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.15188892955002	3.69749310327746	-0.545604173727444	1.22343511411071	0.850785847023478	0.609572795311029	0.445960858434271	0.64129436994782	0.472878233406664	NA	NA	0.0588407545743565	0.524788058373477	78.7021070222364
a5699	loss_cnaOV42	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.15188892955002	3.69749310327746	-0.545604173727444	1.22343511411071	0.850785847023478	0.609572795311029	0.445960858434271	0.64129436994782	0.472878233406664	NA	NA	0.0588407545743565	0.524788058373477	78.7021070222364
a5700	loss_cnaOV43_(NF1)	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.15188892955002	3.69749310327746	-0.545604173727444	1.22343511411071	0.850785847023478	0.609572795311029	0.445960858434271	0.64129436994782	0.472878233406664	NA	NA	0.0588407545743565	0.524788058373477	78.7021070222364
a5701	loss_cnaOV44	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.15188892955002	3.69749310327746	-0.545604173727444	1.22343511411071	0.850785847023478	0.609572795311029	0.445960858434271	0.64129436994782	0.472878233406664	NA	NA	0.0588407545743565	0.524788058373477	78.7021070222364
a5702	loss_cnaOV21, loss_cnaOV22	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	-0.0924910177907127	0.96001207903903	-1.05250309682974	1.5573879858559	2.10295055899526	0.508760707030676	0.675813032069407	0.500488750117171	0.473595685211398	NA	NA	0.414642057437092	0.366905539311201	78.7942046365397
a5703	loss_cnaOV83	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.21929991059198	1.58440607217602	0.634893838415966	1.20678682477392	1.51463478261946	0.429766485441251	0.526102726166989	0.419172889531798	0.473656908945941	NA	NA	0.325168782233928	0.337126282148465	78.7942046365397
a5704	SMAD4_mut	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	2.84562378694534	2.49448195009092	0.351141836854424	0.876300857057841	1.05272710022442	0.338624159942288	0.400709224493257	0.333554476539616	0.473708021397934	NA	NA	0.393931654840398	0.502184085159242	78.7942046365397
a5705	gain_cnaOV19	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.38836061024744	0.815551827124637	0.572808783122804	0.641439300503959	1.2769552198444	0.460189575052315	0.893005437416707	0.448573900024937	0.473812207985447	NA	NA	0.844486030649187	0.263818389105741	78.7942046365397
a5706	loss_cnaOV102	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.70895937921062	2.93751675913874	0.771442620071883	0.317283285594517	1.67422867120307	0.476336797713071	2.43140012442311	0.46077494271887	0.4738811715858	NA	NA	0.662618201744521	0.0458064773378255	78.7942046365397
a5707	SMAD4_mut	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	3.29369771067832	2.86514622967231	0.428551481006004	1.30094446635049	1.24775729027751	0.342464902372799	0.329415660768527	0.343457405013992	0.473929859607021	NA	NA	0.230393207096827	0.632143139327855	78.7942046365397
a5708	loss_cnaOV44	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.59808582776901	0.942738981405558	0.655346846363457	1.21092375217158	1.5709365132053	0.422929904931112	0.541195797991578	0.417169529675202	0.474205489506293	NA	NA	0.790467083732769	0.455817647293408	78.8008424456305
a5709	loss_cnaOV20	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.3693095318345	2.81933528835765	-0.450025756523148	0.530582270759242	1.79840129931991	0.267015305412758	0.848173377295812	0.250236561046376	0.474332131029505	NA	NA	0.320055031148081	0.294619769040753	78.8008424456305
a5710	loss_cnaOV58	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	2.49497371715872	1.79423230832281	0.700741408835917	1.15968793698175	1.39456830670135	0.512788303604704	0.604249976644314	0.502479086516327	0.474348765723021	NA	NA	0.033842989496361	0.271866917424491	78.8008424456305
a5711	loss_cnaOV56	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.19864821880528	3.8018324687842	0.396815750021085	1.29790329299239	0.826712047449964	0.449652626260458	0.305735991397483	0.479992702713216	0.474385463735708	NA	NA	0.939629456406163	0.653252662099336	78.8008424456305
a5712	PTEN_mut	292	Masitinib	KIT	3	29	2.99573227355399	NA	3.17244085705877	4.10052865106705	-0.928087794008286	0.424891286828108	1.05100479323232	0.908752649466891	2.1842947190954	0.883048107853046	0.474398127787529	NA	NA	0.103818578646889	0.0301289466948857	78.8008424456305
a5713	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	261	TL-1-85	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.79435715251188	3.48874630393114	0.305610848580737	0.984116290042435	0.95255803488203	0.318692282811236	0.310543430357767	0.320831736639108	0.474636105748352	NA	NA	0.727787009483927	0.482439252884108	78.8008424456305
a5714	loss_cnaOV34	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.31121751234707	4.56703686645148	-0.255819354104412	1.63912588269887	0.855073833867933	0.257958381846471	0.156070596410325	0.299178087285412	0.47467897056041	NA	NA	0.324303755031723	0.748923409640655	78.8008424456305
a5715	loss_cnaOV102	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	3.65060601399714	2.47723122392988	1.17337479006725	2.36681419520183	2.32410829486715	0.504247961669058	0.495761261042796	0.504870961761411	0.474714898394638	NA	NA	0.38474350623404	0.485767978097408	78.8008424456305
a5716	loss_cnaOV59	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.738312856376589	0.344135015553376	0.394177840823213	0.596743340989649	0.930066810019983	0.432685619975755	0.660548369370159	0.423816694216563	0.474809020904408	NA	NA	0.909409345543408	0.379696852926208	78.8008424456305
a5717	loss_cnaOV21, loss_cnaOV22	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.79173164024484	3.22285910055906	0.568872539685781	1.26502143651136	1.01745521754895	0.549209661799468	0.449693991948943	0.55911309890984	0.474886817256746	NA	NA	0.0911216047234235	0.521071962413367	78.8008424456305
a5718	gain_cnaOV18_(CCNE1)	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-2.08410278839846	-2.82476584853511	0.740663060136657	2.69569110171168	1.62940249171301	0.419578032683639	0.274758135183351	0.454561143672973	0.474975140613652	NA	NA	0.695517046372369	0.625986444111152	78.8008424456305
a5719	ARID1A_mut	304	SB52334	ALK5	8	24	2.99573227355399	NA	4.74702348553865	4.239846139978	0.507177345560645	0.5533421891231	1.15603010881952	0.484451526312141	0.916570895062937	0.438723301141826	0.475258491806715	NA	NA	0.350585800407051	0.110187825645876	78.8008424456305
a5720	SMARCA4_mut	293	MP470	PDGFR	3	29	2.99573227355399	NA	3.45263575441348	4.1109606902796	-0.658324935866121	1.53072105261839	1.78622881374303	0.371863012994683	0.430075051715019	0.368555770011686	0.475350812067689	NA	NA	0.621310168396597	0.542731181278286	78.8008424456305
a5721	loss_cnaOV39	1375	Temozolomide	DNA akylating agent	10	23	3.40119738166216	NA	6.08409591611962	5.88771223188921	0.196383684230412	0.893612337648321	0.606626033990767	0.279695233644036	0.219763846084786	0.323731052125272	0.475393484609343	NA	NA	0.908470302914124	0.537088031286591	78.8008424456305
a5722	loss_cnaOV85	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	6	13	-0.669430653942629	NA	-4.50721507937847	-3.74026467666999	-0.766950402708476	2.03603070611783	1.69760580103257	0.425198683308581	0.376689015742226	0.451783566150622	0.475470455698747	NA	NA	0.588615996249514	0.444277671071936	78.8008424456305
a5723	loss_cnaOV42	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.28913029244451	2.54248934966027	-0.253359057215755	0.343718325370687	0.652702864776366	0.403004364431326	0.737112450849156	0.388169059595844	0.475512291838752	NA	NA	0.857741494250399	0.271752693513634	78.8008424456305
a5724	gain_cnaOV18_(CCNE1)	301	PHA-793887	CDK-pan	4	28	2.32630161961136	NA	3.60829092925868	2.9243464441293	0.68394448512938	1.27060093261185	1.65354821174916	0.422361624413404	0.53828426185983	0.413622342711064	0.475583596398285	NA	NA	0.662639991963785	0.382052856663112	78.8008424456305
a5725	loss_cnaOV38	1218	JQ1	BRD2, BRD3, BRD4	8	23	0	NA	2.44903668455672	2.24005464966387	0.208982034892845	1.0385038271049	0.855867773140013	0.231343855257018	0.201233764805121	0.244175609190343	0.475651295439412	NA	NA	0.593416458064295	0.619296475022381	78.8008424456305
a5726	TP53_mut	301	PHA-793887	CDK-pan	22	10	2.32630161961136	NA	3.14681015977527	2.70850406375991	0.43830609601536	1.60924379700738	1.65330466431232	0.270127832622157	0.272367739947454	0.265109090584747	0.475769877283847	NA	NA	0.662642368506107	0.492809919464728	78.8008424456305
a5727	gain_cnaOV48_(SOX17)	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	1.99285238745043	2.43498312407231	-0.442130736621878	0.62446621271338	0.959627412610756	0.469849708320859	0.708013864674547	0.460731666073419	0.476113209517142	NA	NA	0.73415003793314	0.349956966515561	78.8008424456305
a5728	gain_cnaOV49	1030	KU-55933	ATM	3	30	2.30258509299405	NA	3.79054701296873	4.1870395179469	-0.396492504978165	0.280809538555293	1.0639689286744	0.384367996064964	1.41196238211151	0.372654214134011	0.476134512791707	NA	NA	0.528672695645454	0.147037310866539	78.8008424456305
a5729	gain_cnaOV26	152	CP466722	ATM	3	29	2.77258872223978	NA	3.00356080807721	2.61002246538592	0.39353834269129	0.862778094508014	0.808259999572627	0.484648103286595	0.456129270314518	0.486895730209804	0.476153345155247	NA	NA	0.554911428849537	0.517191874662813	78.8008424456305
a5730	TP53_mut	1166	QL-VIII-58	MTOR, ATR	17	6	2.30258509299405	NA	-1.04613154665702	-1.54933315687361	0.50320161021659	1.31685770673084	1.34851490116384	0.3799285586338	0.382122994492557	0.373152428484327	0.47615606431603	NA	NA	0.0485057442494011	0.450353677359759	78.8008424456305
a5731	loss_cnaOV21, loss_cnaOV22	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.54490912800112	5.74525696512646	-0.200347837125341	0.736052892416406	0.596057698168083	0.330390519532885	0.272192174216739	0.336121549543086	0.47616906847625	NA	NA	0.191243674998238	0.688055494427446	78.8008424456305
a5732	loss_cnaOV34	341	EX-527	SIRT1	5	26	2.99573227355399	NA	5.99582053257677	5.73052338395002	0.265297148626752	0.697657319458589	0.535138811925902	0.473436782092931	0.380268566282131	0.495753891727604	0.476249934071453	NA	NA	0.109760752360192	0.457261263192551	78.8008424456305
a5733	loss_cnaOV41	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.46481542178162	2.93232613646726	-0.467510714685643	1.31521642212531	1.08197496542555	0.41895614915042	0.355462954097072	0.432090140368234	0.47629419527457	NA	NA	0.389578776232999	0.487086771000531	78.8008424456305
a5734	gain_cnaOV49	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	0.545202769115878	1.23014099357628	-0.6849382244604	0.911028865536792	1.52301131217444	0.459342528537959	0.751829333153811	0.449726288298211	0.476490896378841	NA	NA	0.812625263260083	0.327093729684829	78.8008424456305
a5735	loss_cnaOV55	298	OSI-930	KIT, VEGFR, PDGFR	7	25	2.32630161961136	NA	4.80940967561085	4.35136992811332	0.458039747497537	0.863290556168574	0.998394243610087	0.470810182416935	0.530574259413184	0.458776430682647	0.476581478680669	NA	NA	0.0309030947416465	0.256442209059848	78.8008424456305
a5736	TP53_mut	202	GSK-1904529A	IGF1R	12	7	0.0237165266173161	NA	2.39582664434867	2.65732954134385	-0.261502896995175	0.880702992485195	0.512704238908782	0.339111387170116	0.296925182753448	0.510046294042246	0.476632604956393	NA	NA	0.748108521687646	0.424662395348549	78.8008424456305
a5737	ARID1A_mut	306	TG101348	JAK2	8	24	2.32630161961136	NA	2.44867874556494	2.94918524247011	-0.500506496905162	1.3413694350806	1.40513463560337	0.359942568388738	0.37313098376592	0.35619824906689	0.476651256065116	NA	NA	0.626579055262594	0.383505123758798	78.8008424456305
a5738	gain_cnaOV48_(SOX17)	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.608337058574582	0.195903794340718	-0.8042408529153	1.02869362448037	1.65373187405033	0.496937508982487	0.781807949205044	0.486318771219876	0.476668871907347	NA	NA	0.460706653552612	0.310977374526459	78.8008424456305
a5739	gain_cnaOV18_(CCNE1)	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.05129626059867	5.74352935227815	0.307766908320522	0.322647466863771	0.57531085609475	0.548069227700011	0.953879822185208	0.534957588684603	0.476715616513113	NA	NA	0.109767355684591	0.235016540019222	78.8008424456305
a5740	gain_cnaOV96	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	8.16758082224724	8.84490531145921	-0.677324489211975	1.78520108318441	1.69821150745525	0.396695651616029	0.379410754111674	0.398845777595121	0.477008119662004	NA	NA	0.921589237002408	0.516913407175777	78.8008424456305
a5741	gain_cnaOV95_(MECOM)	1042	BIRB 0796	p38, JNK2	8	25	2.30258509299405	NA	4.58905086538173	4.33620182839727	0.252849036984456	1.02059085561292	0.807611612509827	0.293899544024004	0.247747699868039	0.313082468191205	0.477219601590723	NA	NA	0.869206121927173	0.536863992134492	78.8008424456305
a5742	loss_cnaOV70	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.67519694771549	2.32399101542319	0.351205932292297	1.01129595940808	0.857289262010078	0.404425728074661	0.347283037200962	0.409670280330851	0.477237634870919	NA	NA	0.649743839050021	0.613383623126141	78.8008424456305
a5743	loss_cnaOV20	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.12820529807242	3.55396685464364	-0.425761556571214	1.27889194794238	1.07226657161543	0.383042907020338	0.33291440864588	0.397066893477597	0.477321706777712	NA	NA	0.771986909915575	0.572727385317107	78.8008424456305
a5744	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1013	Nilotinib	ABL	7	14	0.693147180559945	NA	3.51067647022579	3.11864179770694	0.392034672518851	1.15119676559045	0.960340573294458	0.382674660338528	0.340545321388023	0.408224627200716	0.477394390189318	NA	NA	0.563906217879492	0.455132038596261	78.8008424456305
a5745	loss_cnaOV42	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.41212897052878	1.87180352561845	0.540325444910326	0.751241120833371	1.39048555397178	0.403122284095501	0.719243702089855	0.388587600473045	0.477496804034557	NA	NA	0.838651104645227	0.279970226305338	78.8008424456305
a5746	loss_cnaOV39	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	3.09853868682133	2.25725186107736	0.841286825743976	2.03136586090741	1.41486993727914	0.540044231596034	0.414148353053532	0.594603647711824	0.47762132606326	NA	NA	0.225738153013511	0.424501014022846	78.8008424456305
a5747	gain_cnaOV72_(ASXL1)	164	JQ12	HDAC	4	15	1.63315443905142	NA	1.19584065659592	1.95337369769737	-0.757533041101451	2.23435321483579	2.21714334489055	0.341201886194815	0.339039072278966	0.341670755229788	0.47801873312478	NA	NA	0.658908407176958	0.574059455331816	78.8008424456305
a5748	gain_cnaOV50	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.2807606982465	4.41757881892526	-0.136818120678754	0.912421675578939	0.759781699114571	0.176093279955186	0.149950537498949	0.180075567545517	0.478069989937675	NA	NA	0.042587549108982	0.790681054516036	78.8008424456305
a5749	SMAD4_mut	293	MP470	PDGFR	3	29	2.99573227355399	NA	3.2883781479289	4.12795285646766	-0.839574708538763	3.89951716236276	1.49848490093191	0.476116740661984	0.215302221680711	0.560282394581774	0.478073766903589	NA	NA	0.621348289334061	0.745886317381337	78.8008424456305
a5750	loss_cnaOV85	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	6	13	2.77258872223978	NA	-0.461008433642286	-0.619395310104096	0.15838687646181	1.92714044266462	1.87131523006483	0.0838955410226677	0.0821875110683739	0.0846393349004714	0.47817214709927	NA	NA	0.0418035913875731	0.870054219890841	78.8008424456305
a5751	KRAS_mut	221	TAK-715	p38a	7	25	2.99573227355399	2.32630161961136	4.43715396874365	4.23336040561574	0.203793563127904	0.52220665996737	0.970642621862194	0.226681226459618	0.39025462283579	0.209957360760567	0.478184357212007	NA	NA	0.52052208533001	0.470728290134092	78.8008424456305
a5752	loss_cnaOV34	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	1.47212016276607	1.1703342313821	0.301785931383973	0.932532831953836	1.28348603194491	0.242636347147021	0.323619631441472	0.235129891461823	0.47820580610485	NA	NA	0.26582710233794	0.55134253713755	78.8008424456305
a5753	gain_cnaOV72_(ASXL1)	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-0.525679375657051	-0.778734034410386	0.253054658753335	1.02795988198975	0.910410571041596	0.273154244092301	0.246171726335774	0.27795663495407	0.478234380099557	NA	NA	0.0414840210341115	0.627407012340185	78.8008424456305
a5754	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.28082046829168	3.72289645252715	-0.442075984235467	0.247294013334816	1.08825214655618	0.419710220949908	1.78765340201314	0.406225694692574	0.478282916833093	NA	NA	0.830570971011106	0.0956257463894257	78.8008424456305
a5755	gain_cnaOV96	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	1.30793603537337	0.806583595566547	0.501352439806823	1.18151627788098	1.25173161838285	0.402728850955121	0.424329693286991	0.400527103768886	0.478362807628404	NA	NA	0.844514226305405	0.474566730691764	78.8008424456305
a5756	loss_cnaOV84	1129	PF-4708671	RPS6KB1 (p70S6KA)	6	26	2.30258509299405	NA	4.5653069103855	4.11204432245292	0.453262587932572	1.17733823735622	0.916259399752448	0.469852217951028	0.384989269481639	0.494688063287573	0.47838041688179	NA	NA	0.0476215128145145	0.408685021682286	78.8008424456305
a5757	gain_cnaOV49	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	0.66037555545576	1.51599182884568	-0.855616273389923	0.976002797263748	1.83223355315165	0.478959138670538	0.876653505285711	0.466979917444568	0.478396390553066	NA	NA	0.613735810291486	0.2695951730906	78.8008424456305
a5758	loss_cnaOV55	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	8	25	-2.30258509299405	NA	-0.0408207272564642	-0.425925348922786	0.385104621666322	1.36048166217524	1.42214092621131	0.273423674397329	0.28306491176852	0.270792165929905	0.478449450488638	NA	NA	0.888709047157985	0.503505476365073	78.8008424456305
a5759	loss_cnaOV40	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.68130140932525	4.4699297723605	0.211371636964749	0.666304171600026	0.578790729290362	0.353866649155082	0.317229946883228	0.365195270532245	0.478506865581633	NA	NA	0.614183371224856	0.465856354770448	78.8008424456305
a5760	SMAD4_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	2.36570576873295	1.76605231553783	0.599653453195125	2.21627218109913	1.58545146512413	0.358630668568323	0.270568506119919	0.378222522975925	0.478621010412956	NA	NA	0.34372296772585	0.691644257982971	78.8008424456305
a5761	loss_cnaOV21, loss_cnaOV22	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	2.19465590572477	2.88224695552327	-0.687591049798501	2.32593274244024	1.49235488139752	0.440866076130933	0.295619489442811	0.460742319651614	0.478665116248654	NA	NA	0.968737403792409	0.662171196165027	78.8008424456305
a5762	loss_cnaOV83	155	AP-24534	ABL	4	15	-0.669430653942629	NA	1.13822024595728	0.695305666001019	0.442914579956262	1.77169794916477	1.12171407925791	0.351240235232136	0.249994408	0.394855149049462	0.478864979259951	NA	NA	0.58247580097064	0.661530757267533	78.8008424456305
a5763	loss_cnaOV44	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	3.13711743935888	2.36750044705945	0.769616992299436	2.21823285972513	1.38098384686912	0.530075906148559	0.346950496619549	0.557296158129774	0.47892377613153	NA	NA	0.238997216503306	0.611402335665492	78.8008424456305
a5764	loss_cnaOV40	326	GSK690693	AKT	7	25	2.32630161961136	NA	4.64725764991825	4.01323972838246	0.634017921535791	0.761170206679912	1.56990666693641	0.438815427092339	0.832951573737054	0.403857079461318	0.478950805552472	NA	NA	0.0927973315411005	0.151219955662319	78.8008424456305
a5765	loss_cnaOV33_(ZFHX3)	1030	KU-55933	ATM	4	29	2.30258509299405	NA	3.85476253836687	4.19185435944295	-0.337091821076079	1.66892744636414	0.938462510499656	0.326638643222261	0.201981111767593	0.359195830738731	0.479002723726194	NA	NA	0.52871828629119	0.716949617283528	78.8008424456305
a5766	gain_cnaOV18_(CCNE1)	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.32760346602237	5.02406188678422	0.303541579238146	0.120557878842701	0.645932633986387	0.494391332302917	2.51780789569295	0.469927610507667	0.479085270504776	NA	NA	0.109743211927243	0.0342179033792146	78.8008424456305
a5767	gain_cnaOV26	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	3.30844900228957	3.79162566639143	-0.483176664101861	2.25501833272986	1.50758105196266	0.308423495100468	0.214267288690705	0.320497968233836	0.479099988431374	NA	NA	0.164213057609259	0.748718809991868	78.8008424456305
a5768	gain_cnaOV50	281	CH5424802	ALK	4	28	1.63315443905142	NA	3.68425255136694	3.96237038460273	-0.27811783323579	1.46279849341126	0.594565109738397	0.381257141818212	0.190127235219676	0.467766824323343	0.479145284835032	NA	NA	0.955680703628465	0.730975193219541	78.8008424456305
a5769	loss_cnaOV56	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.4911930291714	1.88225639696268	0.608936632208726	0.78293587059212	1.37170347974909	0.454253483415447	0.777760548572386	0.443927307321631	0.479153263491955	NA	NA	0.838661661524411	0.315216253389605	78.8008424456305
a5770	TP53_mut	288	KIN001-055	JAK3, MNK1	22	10	2.32630161961136	NA	3.8878859618917	3.60981168621658	0.278074275675124	1.05537950879555	0.972182004535503	0.26968037911055	0.263482731432293	0.286031087160458	0.479241758116092	NA	NA	0.716532315346065	0.474400919575696	78.8008424456305
a5771	loss_cnaOV40	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	6.0687597946481	5.75339950533978	0.315360289308324	0.90141887209601	1.3702738453136	0.244426307904869	0.349848776268726	0.230143989383488	0.479298713559765	NA	NA	0.570026003105938	0.482050693730575	78.8008424456305
a5772	SMARCA4_mut	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	3.26043933217635	2.51759329446307	0.742846037713276	3.36837235377437	2.25195243117323	0.317050534925603	0.220535605833747	0.32986755289776	0.479368073691029	NA	NA	0.384831378810001	0.741920931614055	78.8008424456305
a5773	gain_cnaOV4_(KRAS)	229	LY317615	PRKCB (PKCbeta)	8	24	2.99573227355399	2.32630161961136	3.11711320751462	2.62632061602967	0.490792591484954	2.4654974954043	1.35253198014918	0.292218476137269	0.19906432369118	0.362869491212193	0.479680279584317	NA	NA	0.320157451412694	0.6052762845571	78.8385055756219
a5774	loss_cnaOV39	205	BMS-708163	g-secretase	9	23	2.32630161961136	0.940007258491471	5.24624214670291	4.98991162494441	0.256330521758497	0.633322911721769	0.60292662263757	0.419402577084897	0.40473906282915	0.425143810431111	0.480016256218061	NA	NA	0.109755836690432	0.314470693705062	78.8623673481314
a5775	gain_cnaOV19	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.83116911537064	-3.57375387573375	0.742584760363107	3.10524431174215	1.50437027645746	0.419646847457751	0.239138916559674	0.493618341165161	0.480113997018989	NA	NA	0.680004142901939	0.721568654348405	78.8623673481314
a5776	loss_cnaOV39	301	PHA-793887	CDK-pan	9	23	2.32630161961136	NA	3.38120844306767	2.86452122456722	0.516687218500446	1.72897301374913	1.57628418461957	0.319256002544405	0.298840533884363	0.327788113045837	0.480114040541263	NA	NA	0.662697359869138	0.449518124188547	78.8623673481314
a5777	gain_cnaOV50	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	4.7310572378733	4.93759311435933	-0.206535876486033	0.962533864612154	0.852416672264378	0.238919273992508	0.214575179200843	0.242294505968996	0.480493731624397	NA	NA	0.15324950393071	0.706799205756006	78.8623673481314
a5778	loss_cnaOV84	305	TPCA-1	IKK	6	26	2.99573227355399	NA	3.00105477324344	3.39999660486235	-0.398941831618914	1.09589981573902	1.25536043106443	0.324284986504872	0.364031297285954	0.317790669314508	0.480597143865599	NA	NA	0.993596315791641	0.456290437685732	78.8623673481314
a5779	loss_cnaOV33_(ZFHX3)	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	5.97714007800037	5.69066496645248	0.286475111547892	0.99241185464523	0.540876117768747	0.476282227589309	0.288665547682622	0.529650140090628	0.480606026402816	NA	NA	0.191320294804381	0.608368238207558	78.8623673481314
a5780	BRCA1_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.33869900490556	0.820689234573797	0.51800977033176	0.08687371485151	1.29045285250347	0.4154388794729	5.9627906003234	0.401417044665229	0.480649333743929	NA	NA	0.844528227251011	0.0428525751657401	78.8623673481314
a5781	loss_cnaOV33_(ZFHX3)	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	0.771317197109104	1.53124552168926	-0.759928324580155	0.337539086369769	1.88288152328924	0.425459525536864	2.25137874476458	0.403598588217394	0.480650453564463	NA	NA	0.613768717902144	0.0678773237784661	78.8623673481314
a5782	loss_cnaOV42	281	CH5424802	ALK	4	28	1.63315443905142	NA	3.68511395221631	3.96224732733853	-0.27713337512222	1.22673589917746	0.651247112905487	0.379884837311175	0.225911196784933	0.425542577664278	0.480698604951239	NA	NA	0.955683444759064	0.685649480999781	78.8623673481314
a5783	loss_cnaOV44	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	2.32192843091158	2.9656740861999	-0.643745655288322	0.162618389221939	1.28588237377396	0.517901009226397	3.95862767039064	0.5006256158555	0.480782418233903	NA	NA	0.230518495474992	0.0181797853371339	78.8623673481314
a5784	gain_cnaOV95_(MECOM)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	1.54181125149217	1.04692207678468	0.494889174707494	1.91217480696147	1.47034977042388	0.312149260611396	0.25880958838376	0.336579217178253	0.480905197664123	NA	NA	0.532706801432193	0.618517608922718	78.8623673481314
a5785	NF1_mut	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	1.19844339664205	2.16239716897458	-0.963953772332537	1.46957209668239	2.0254517484572	0.487606277614621	0.655941804086165	0.475920383226501	0.481066199020392	NA	NA	0.131563786674853	0.299084882630937	78.8623673481314
a5786	loss_cnaOV52, loss_cnaOV53	1058	GDC0941	PI3K (class 1)	9	24	1.38629436111989	0.693147180559945	1.24257439489078	0.694357352075941	0.548217042814842	1.02415122885382	1.42472992195961	0.41128725231905	0.535289152001878	0.384786642271689	0.481183735291058	NA	NA	0.162382568861746	0.235660765029951	78.8623673481314
a5787	gain_cnaOV50	344	THZ-2-49	CDK9	4	28	2.99573227355399	NA	3.49907118704792	2.4569728138488	1.04209837319913	1.78023775707802	2.37953938877372	0.447912571060168	0.585370335538531	0.437941215899	0.481199151976411	NA	NA	0.384865575678133	0.34685123278415	78.8623673481314
a5788	loss_cnaOV35	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.59202833794555	-2.27634809009022	-0.315680247855327	1.27514696278193	0.656869802211822	0.417393449754395	0.24756381583392	0.480582676798909	0.481222232642305	NA	NA	0.672929723894953	0.71288338457562	78.8623673481314
a5789	loss_cnaOV1	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	3.00751521414514	2.48999753526609	0.517517678879059	0.644539247552834	1.05383371215361	0.501307290017216	0.802926556984626	0.491080967434094	0.481293254463837	NA	NA	0.394069263415558	0.299723977531769	78.8623673481314
a5790	KRAS_mut	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-2.67284454118493	-3.60343973339357	0.930595192208639	1.32594268651447	1.80593593232837	0.52986475723425	0.701836664339478	0.515298010051129	0.481362479797549	NA	NA	0.680031560490667	0.360615382326171	78.8623673481314
a5791	loss_cnaOV41	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.01856651863963	5.2226943217208	-0.204127803081176	0.895534812570482	0.753484517500647	0.263754036754519	0.227939550998873	0.270911741834165	0.481417750068295	NA	NA	0.332491375153113	0.651596771524372	78.8623673481314
a5792	KRAS_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.90117315187688	2.30484638083839	0.596326771038491	0.887489982686736	0.982528224323566	0.613612374981829	0.671925072588657	0.606930932135858	0.48144539202179	NA	NA	0.408114739961928	0.370969154602121	78.8623673481314
a5793	loss_cnaOV20	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	2.92523464942198	2.2401003990322	0.685134250389779	1.65558619925868	1.52802309890985	0.443431131837026	0.413831820231746	0.448379511329757	0.481514777176251	NA	NA	0.241114645507333	0.425965997123606	78.8623673481314
a5794	loss_cnaOV39	263	FR-180204	ERK	9	23	2.99573227355399	NA	4.6479642090371	4.87586129050086	-0.227897081463762	0.835004840482436	0.710797869197337	0.305514720626821	0.272929054317926	0.320621503439666	0.481572650834023	NA	NA	0.76467509360808	0.482848669686467	78.8623673481314
a5795	loss_cnaOV38	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-1.94083473697222	-1.47398751521621	-0.466847221756013	2.60106411249002	0.805660222890066	0.355095326175915	0.179483165952836	0.579459191967226	0.481654002508448	NA	NA	0.620468681614797	0.745371487880981	78.8623673481314
a5796	loss_cnaOV54	1149	TW 37	BCL2, BCL2L1	11	22	1.6094379124341	NA	-0.45667471534759	-0.882251271497844	0.425576556150254	0.993051070185928	0.864310152959514	0.468781089603178	0.428554551651179	0.492388704093111	0.481913843070113	NA	NA	0.0415109301410405	0.24192854002529	78.8912979838826
a5797	loss_cnaOV85	204	Tipifarnib	Farnesyl-transferase (FNTA)	6	13	2.77258872223978	NA	2.12653907130012	1.73805537900026	0.388483692299861	1.46103903369813	1.75936194662602	0.231634979577887	0.265895491728612	0.220809420736231	0.482008986103325	NA	NA	0.343839203172919	0.62351050226764	78.8932616197967
a5798	gain_cnaOV4_(KRAS)	223	ZSTK474	PI3K	8	24	1.63315443905142	2.32630161961136	0.99016222464528	0.680965119774665	0.309197104870615	0.895302647627121	1.08959680227037	0.2951790686631	0.345354842510631	0.283772037717389	0.482191329951732	NA	NA	0.771415132010869	0.437013539658541	78.8994201914483
a5799	KRAS_mut	1001	AICAR	AAPK1 (AMPK) agonist	7	24	7.60090245954208	NA	8.41075730796542	8.8484056773989	-0.437648369433486	1.12958724762165	1.25632091803133	0.355473272804261	0.387440961603413	0.348357145974521	0.482226436024859	NA	NA	0.528941330750585	0.398766602937594	78.8994201914483
a5800	loss_cnaOV41	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.07640692805789	2.40886280185665	-0.33245587379876	1.10588612670953	0.822777183005313	0.383947080696224	0.300623966400551	0.404065499950323	0.482319082331631	NA	NA	0.64980983142821	0.551028969811669	78.8994201914483
a5801	loss_cnaOV83	1016	Temsirolimus	MTOR	5	26	-1.6094379124341	NA	-2.19681734799426	-1.99715421840972	-0.199663129584538	1.36744925873676	1.60235450221754	0.127008772723137	0.146011362621957	0.124606090168074	0.482491659397949	NA	NA	0.0374191822779809	0.780807664662642	78.8994201914483
a5802	loss_cnaOV1	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.5641935464661	3.90593406349095	0.658259482975156	0.389247975460206	1.19747605098401	0.567485081881073	1.69110573329739	0.549705760239833	0.482523870191843	NA	NA	0.0821605630340964	0.0750513669657488	78.8994201914483
a5803	gain_cnaOV4_(KRAS)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	6	13	1.63315443905142	NA	1.51637550444323	1.0205932542913	0.495782250151926	1.90456883305936	1.42849143179002	0.313103923196662	0.26031206724912	0.347067010076966	0.482545539700011	NA	NA	0.532755131992332	0.586093703143799	78.8994201914483
a5804	gain_cnaOV95_(MECOM)	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.77988234458339	2.14931340110024	0.630568943483147	1.30000716243946	1.40551147517393	0.45484399306309	0.485050361030233	0.448640195844088	0.48274964661949	NA	NA	0.745781118687898	0.437818931824183	78.9191933135316
a5805	loss_cnaOV87, loss_cnaOV88	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	4.6507031702947	3.77768361492825	0.873019555366447	1.85982308302615	1.44527268987053	0.586024548145369	0.469410001055553	0.604051790008329	0.482955981352468	NA	NA	0.0687788629650624	0.506281386412195	78.9194283704815
a5806	loss_cnaOV33_(ZFHX3)	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.27617809884705	4.56304853196512	-0.286870433118068	1.89053602869353	0.83994048233438	0.289324324174581	0.151740262425103	0.34153661973857	0.482990209740062	NA	NA	0.32445667894837	0.783204563453621	78.9194283704815
a5807	MLL2_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	-1.64914580193805	0.00201208173491247	-1.65115788367296	1.92852479706247	1.50900519948865	1.07106267154009	0.856176641434948	1.09420291211222	0.483035569117035	NA	NA	0.0998048271503918	0.273228482757768	78.9194283704815
a5808	loss_cnaOV82	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.28122337293233	3.63633270062976	0.644890672302561	1.17260117578199	1.22245937554948	0.5289005403208	0.549965909655933	0.527535462691911	0.483083786798161	NA	NA	0.197204976520105	0.445436074193263	78.9194283704815
a5809	gain_cnaOV72_(ASXL1)	151	QS11	ARFGAP	4	15	2.32630161961136	NA	3.05992608533497	3.95527371391687	-0.8953476285819	0.837006411622945	1.52422256392037	0.627345556805941	1.06970223423478	0.587412658607433	0.483322054966412	NA	NA	0.0636162110365044	0.153081953827345	78.9380907770195
a5810	loss_cnaOV55	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	8	25	0.693147180559945	NA	2.59358004068528	2.8632378159632	-0.26965777527792	1.0044319092054	0.950124412265251	0.28011874566489	0.268467949700289	0.283813121520593	0.483364414141022	NA	NA	0.966119483559524	0.51659917809732	78.9380907770195
a5811	gain_cnaOV19	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.71121844316552	4.33099447980292	0.380223963362599	0.281126063343847	1.09988475316296	0.356995696129501	1.35250342440695	0.345694366859055	0.483527525340782	NA	NA	0.350742486583584	0.172163924643817	78.951139579446
a5812	gain_cnaOV49	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.26189572457421	2.59443133298231	0.667464391591899	0.552011559576237	1.75730097930083	0.391373206028511	1.20914930133762	0.379823604182739	0.4839155937856	NA	NA	0.639313633331346	0.180291368027074	78.9749904519647
a5813	PIK3R1_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	4.78572376414121	5.2084975276782	-0.422773763536988	0.468301338199329	0.584043117746138	0.741746787764874	0.902781455125881	0.723874232382877	0.484254987485226	NA	NA	0.0117172679367623	0.121427805415816	78.9749904519647
a5814	loss_cnaOV40	223	ZSTK474	PI3K	7	25	1.63315443905142	2.32630161961136	1.02577640693065	0.683361032929585	0.342415374001068	0.63026372454995	1.12668534070411	0.327227424875693	0.543289040227686	0.303913933758185	0.48440704617811	NA	NA	0.771434505503534	0.310235702990028	78.9749904519647
a5815	PIK3R1_mut	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	2.56924777940399	2.26500528796483	0.304242491439155	0.278373570614728	1.31633692567707	0.245324343063485	1.0929287962478	0.231128129511876	0.48446482621905	NA	NA	0.387237286566782	0.41825339626063	78.9749904519647
a5816	loss_cnaOV38	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	3.42485794427272	3.85066265924797	-0.425804714975247	1.20884550679352	0.942180064906173	0.43472012852465	0.352240805448085	0.451935602158649	0.484574844203672	NA	NA	0.807072453041749	0.612066584298084	78.9749904519647
a5817	loss_cnaOV87, loss_cnaOV88	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.21959016545056	4.55914497753417	-0.33955481208361	2.28589600782061	0.830466615810706	0.342600866518627	0.1485434205764	0.408872320234251	0.484620756617772	NA	NA	0.324486174949338	0.821593812911222	78.9749904519647
a5818	loss_cnaOV42	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	2.9436489737557	2.4809612346688	0.462687739086902	1.14082840362351	1.01964103948326	0.448344742593439	0.405571721055778	0.453775123960668	0.484672977734747	NA	NA	0.394129435981189	0.487670762044681	78.9749904519647
a5819	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.58524823897143	2.82656615060338	-0.241317911631954	1.1364617558424	1.25013335445213	0.195307157254625	0.212341427585549	0.193033735779101	0.484991951517301	NA	NA	0.0940883959777038	0.682920019356875	78.9749904519647
a5820	loss_cnaOV40	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	4.40861823049861	3.83191939663714	0.576698833861468	2.14704122899187	1.3935562981483	0.371269911247624	0.268601657981321	0.413832462045317	0.485010532384206	NA	NA	0.74204853843468	0.639351603499249	78.9749904519647
a5821	SMAD4_mut	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.9627218349466	3.35273050503881	0.609991329907794	1.51368296435333	1.19371415193233	0.500952087421862	0.402984868214061	0.511002846804127	0.485056449144827	NA	NA	0.325699123988157	0.561204085848776	78.9749904519647
a5822	TP53_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	22	10	2.32630161961136	NA	1.47313704217712	0.886755684312569	0.586381357864548	2.38766816314896	2.18816809913572	0.251707657611076	0.245587459310595	0.267978204277887	0.485085717055897	NA	NA	0.362432094582973	0.503098148644402	78.9749904519647
a5823	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1203	QL-XII-61	BTK	6	17	2.30258509299405	NA	3.47742469265018	4.0377196266793	-0.560294934029123	1.67356102816592	1.44042831266317	0.373722315681246	0.334792053949272	0.388978006821601	0.485123799869926	NA	NA	0.0688106231471081	0.486670300483971	78.9749904519647
a5824	TP53_mut	341	EX-527	SIRT1	21	10	2.99573227355399	NA	5.81461166158616	5.68658657522748	0.128025086358686	0.609060233512489	0.455981862209401	0.226192263536786	0.21020102662155	0.280767936115611	0.485276692101565	NA	NA	0.109886933938104	0.520262248324526	78.9749904519647
a5825	loss_cnaOV55	345	KIN001-270	CDK9	7	25	2.99573227355399	NA	5.42006680441739	5.12660446594952	0.293462338467869	0.744178525347781	0.773281703182179	0.382336767360987	0.394344002779069	0.379502498585217	0.48551114099535	NA	NA	0.332568050933488	0.382209338436882	78.9749904519647
a5826	PTEN_mut	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.58437841917909	4.50642287491332	0.0779555442657704	0.120148127525106	0.634895520270654	0.129169848517358	0.648828624062252	0.122784839043341	0.485565796537203	NA	NA	0.614281882680834	0.566086779234447	78.9749904519647
a5827	gain_cnaOV26	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	1.294909896489	1.60873761628265	-0.31382771979365	1.04331085200841	1.06364640956802	0.29555814310034	0.300799823168255	0.295048915664658	0.485575764132719	NA	NA	0.28555927723154	0.664409852562893	78.9749904519647
a5828	gain_cnaOV95_(MECOM)	301	PHA-793887	CDK-pan	9	23	2.32630161961136	NA	2.68708937733073	3.13613303289907	-0.449043655568336	1.70861057045761	1.59038782093745	0.276716638207341	0.262812172259985	0.282348525093489	0.485642635176922	NA	NA	0.662766165148116	0.506947361497255	78.9749904519647
a5829	PIK3R1_mut	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	2.23613279670543	2.79762963057584	-0.561496833870411	1.75117839836687	1.26670082910555	0.421269051290194	0.320639424512121	0.443275018827373	0.485739151820645	NA	NA	0.940886715658481	0.641002247980257	78.9749904519647
a5830	loss_cnaOV40	230	GSK429286A	ROCK2	7	25	2.99573227355399	2.32630161961136	5.83350733245188	5.45621256934109	0.377294763110792	0.95961028386689	0.97922488155482	0.386836662083804	0.393174989320069	0.385299403862902	0.485831831684291	NA	NA	0.303152903445365	0.381988530154074	78.9749904519647
a5831	gain_cnaOV95_(MECOM)	1218	JQ1	BRD2, BRD3, BRD4	8	23	0	NA	2.08961105346531	2.36507226047827	-0.275461207012959	1.37330638714264	0.683297353302213	0.306175631100508	0.200582484427306	0.403135188043274	0.486035989690702	NA	NA	0.593573605995305	0.600601735752404	78.9749904519647
a5832	KRAS_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	7	25	2.32630161961136	NA	0.573058119402085	1.49060659740831	-0.917548478006222	1.47682400994217	2.47896662778557	0.396601027361793	0.62129845657246	0.370133453077526	0.486051844018204	NA	NA	0.362449966394533	0.236193246018328	78.9749904519647
a5833	gain_cnaOV26	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	2.04391763842417	2.41263324667304	-0.368715608248868	2.61504202467001	1.1711299485667	0.280796433983279	0.140997966675276	0.314837485541314	0.486104222661374	NA	NA	0.109324505378399	0.830685146133082	78.9749904519647
a5834	ARID1A_mut	1004	Vinblastine	Microtubules	9	22	-2.30258509299405	NA	-4.09581941834381	-2.9958388454589	-1.09998057288491	1.30715777992935	1.90987947616496	0.623466262662286	0.841505585457601	0.575942401922484	0.486113254694231	NA	NA	0.138604692940571	0.0787760637375268	78.9749904519647
a5835	gain_cnaOV72_(ASXL1)	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.56229217016374	4.38079047803227	0.18150169213147	0.733920435518927	0.61668474430609	0.286474206587524	0.247304317126879	0.294318440349454	0.48612515735196	NA	NA	0.270123922541124	0.624812484820632	78.9749904519647
a5836	gain_cnaOV49	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.66826049363776	2.32470857963813	0.34355191399963	1.01251540835993	0.857487571830041	0.395485517953695	0.339305368750994	0.400649438296144	0.486211038787472	NA	NA	0.64985960122023	0.621051514786256	78.9749904519647
a5837	loss_cnaOV83	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	1.88571151725814	1.34616693414445	0.539544583113692	1.45046352730757	1.84275729360971	0.300790428400136	0.371980799900031	0.292791994357975	0.486220548687831	NA	NA	0.613848950798962	0.491834377758306	78.9749904519647
a5838	ARID1A_mut	1143	HG-5-88-01	EGFR, ADCK4	6	16	2.30258509299405	NA	4.16525050830448	3.41978329381844	0.745467214486049	0.805020087955481	0.861342528569659	0.879490219561512	0.926023121210951	0.86547127276296	0.48622718313532	NA	NA	0.0590298503656097	0.0881610382600461	78.9749904519647
a5839	loss_cnaOV34	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.76216638033212	3.43172196026401	0.330444420068116	1.17514516081564	0.856866265985508	0.365434159416649	0.281194554584866	0.385642933075516	0.486305257095587	NA	NA	0.793795156438262	0.575211773490369	78.9749904519647
a5840	loss_cnaOV56	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-1.00097833765321	-0.795555443961222	-0.20542289369199	0.989083663629464	0.796233269759671	0.253293646432369	0.207690108780269	0.257993356336383	0.48639709554324	NA	NA	0.078125718403113	0.757408078517573	78.9749904519647
a5841	loss_cnaOV59	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-2.2531771889442	-1.99619954306842	-0.256977645875785	1.58168726953196	1.57015525919448	0.163539182352136	0.162470578619393	0.163663844305193	0.486457006351465	NA	NA	0.0374476148652359	0.776867993325495	78.9749904519647
a5842	gain_cnaOV94	223	ZSTK474	PI3K	7	25	1.63315443905142	2.32630161961136	1.02459169833968	0.683692751335058	0.340898947004624	0.607216280523418	1.12994962594783	0.325750163952137	0.561412725480236	0.30169393323058	0.486525989267796	NA	NA	0.771452895083401	0.303258301108976	78.9749904519647
a5843	SMARCA4_mut	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.632739153506435	-0.0554418153063332	-0.577297338200101	1.20898776514219	1.26161563893383	0.458880181182874	0.477504698430266	0.457585749878595	0.486555688382486	NA	NA	0.766631331107929	0.501365311921963	78.9749904519647
a5844	loss_cnaOV38	277	ABT-869	VEGFR and PDGFR family	8	24	0.0237165266173161	NA	2.65597484797066	2.73605620587299	-0.0800813579023361	0.853587594492046	0.454449038636992	0.139754758318333	0.0938173872477504	0.176216365519268	0.486556086391942	NA	NA	0.134794771483003	0.805896120399806	78.9749904519647
a5845	loss_cnaOV39	1149	TW 37	BCL2, BCL2L1	10	23	1.6094379124341	NA	-0.446754970264495	-0.868060875614396	0.421305905349901	1.07649624906357	0.831500486153841	0.463252006837888	0.391367741147626	0.506681490107935	0.486638232406128	NA	NA	0.04154500650219	0.288845364898142	78.9749904519647
a5846	TP53_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	12	7	-0.669430653942629	NA	-4.22934349433848	-3.55922990584557	-0.670113588492909	1.80537560752218	1.82052117299422	0.370078105718826	0.371176826418198	0.368088873907888	0.486777489532912	NA	NA	0.588920618980416	0.451885923717915	78.9749904519647
a5847	gain_cnaOV51_(MYC)	309	Y-39983	ROCK	8	24	2.99573227355399	NA	5.30073630684841	4.85214069265775	0.448595614190663	1.30058848196239	1.20937599106658	0.364337639958141	0.344917412703672	0.370931470034423	0.486779474409655	NA	NA	0.371582257840244	0.407862191580877	78.9749904519647
a5848	PTEN_mut	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	4.12928213734457	3.59633104480852	0.532951092536051	0.105231946250737	2.10897452410147	0.261552587826111	5.06453706810843	0.252706273331166	0.486813485782694	NA	NA	0.746885042147244	0.189075449452082	78.9749904519647
a5849	loss_cnaOV102	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.58684561860746	1.17898074789022	0.407864870717232	1.16289230696752	1.24823463209704	0.328154363683417	0.350733140354865	0.326753368500935	0.486917298381794	NA	NA	0.265982777193311	0.612996030904486	78.9749904519647
a5850	ARID1A_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-3.3427348972273	-4.21093262763173	0.868197730404435	2.16910513270239	1.66703684042853	0.482914489652797	0.400256178142359	0.520802965686863	0.486919728898507	NA	NA	0.588924375692563	0.448199028460251	78.9749904519647
a5851	loss_cnaOV52, loss_cnaOV53	1175	AG-014699	PARP1, PARP2	9	24	1.6094379124341	NA	4.18936616390423	3.79307984565723	0.396286318247005	0.846055338993584	1.13509578427198	0.371047736031008	0.468392905265988	0.349121478326319	0.487086647258795	NA	NA	0.315436221156664	0.290919853298026	78.9885611298992
a5852	PIK3CA_mut	1054	PD-0332991	CDK4, CDK6	7	26	1.38629436111989	0.693147180559945	2.02507926451538	2.35390843578603	-0.328829171270646	1.11506355766112	1.92836135263967	0.182696844855637	0.294897245104462	0.170522589462044	0.487323637982614	NA	NA	0.109847717957517	0.569092437379705	79.0049605495804
a5853	loss_cnaOV34	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	3.39305531569273	2.43800914657387	0.955046169118863	2.35504577099379	2.32176407668995	0.410555499220232	0.405531892790284	0.411345053835287	0.487592705956346	NA	NA	0.384983315942635	0.438338077300195	79.0049605495804
a5854	loss_cnaOV34	326	GSK690693	AKT	5	27	2.32630161961136	NA	4.71819456855342	4.04706755245268	0.671127016100742	0.766848110813274	1.52634267230006	0.463397572606173	0.87517593984679	0.439696162781988	0.487669247393254	NA	NA	0.0929041976463945	0.165040995284977	79.0049605495804
a5855	loss_cnaOV54	1053	MK-2206	AKT1, AKT2	10	22	1.38629436111989	0.693147180559945	1.6723303229506	1.14514669589226	0.527183627058343	0.970981039500979	1.28798499204862	0.438699399840561	0.542939157008957	0.409308827597304	0.48767935519416	NA	NA	0.0968367837698873	0.213442595103779	79.0049605495804
a5856	loss_cnaOV85	235	QL-XII-47	BTK, BMX	7	25	2.32630161961136	NA	2.11547661303221	1.41123627961299	0.704240333419222	0.932476722378976	1.73486930221904	0.43829482682197	0.755236368391623	0.405932788434518	0.487683473591872	NA	NA	0.0782268707945945	0.17081949990148	79.0049605495804
a5857	KRAS_mut	1069	EHT 1864	Rac GTPases	7	26	2.30258509299405	NA	3.92427002392028	4.31145450460382	-0.387184480683538	1.1380134873345	0.928643995354927	0.398055108150416	0.340228376019003	0.416935319261453	0.487708049004525	NA	NA	0.208682056535493	0.430395936553794	79.0049605495804
a5858	loss_cnaOV83	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.673635457374632	0.339117673152806	0.334517784221825	0.720707783599725	0.931102904275465	0.366959769573775	0.464151757250361	0.35927047664203	0.48778296992785	NA	NA	0.909457444135089	0.446550783294613	79.0049605495804
a5859	loss_cnaOV35	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-1.02073555115576	-1.67568406391655	0.654948512760787	2.47520511067255	1.05625532643903	0.501555988753525	0.264603733216609	0.620066471019675	0.487901171985519	NA	NA	0.620624760288224	0.693823620519842	79.0049605495804
a5860	loss_cnaOV57_(ZNRF3)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.13370958655996	3.79461872030842	0.339090866251543	1.06766259142978	0.848718932505928	0.383879898929123	0.317601149439397	0.399532581711526	0.487999579106881	NA	NA	0.939677009539981	0.584071039461909	79.0049605495804
a5861	loss_cnaOV82	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.29003850609199	3.72194286240987	-0.431904356317884	0.939421766053012	1.06136111846328	0.40990439634348	0.459755534654614	0.406934406023115	0.488119384365103	NA	NA	0.830635608623188	0.516942383585522	79.0049605495804
a5862	KRAS_mut	263	FR-180204	ERK	7	25	2.99573227355399	NA	5.00337077074919	4.75811568670437	0.245255084044819	0.495043593496236	0.796597386689504	0.328715411837847	0.495421185663085	0.30787834374407	0.488352803115977	NA	NA	0.764735665163342	0.333341769958127	79.0049605495804
a5863	loss_cnaOV55	1042	BIRB 0796	p38, JNK2	8	25	2.30258509299405	NA	4.5700629688442	4.34227795528928	0.227785013554924	0.943789093862544	0.836230658045315	0.264346094707197	0.241351606027458	0.272394956299941	0.488481498861445	NA	NA	0.869261745566595	0.554346459499782	79.0049605495804
a5864	loss_cnaOV84	341	EX-527	SIRT1	6	25	2.99573227355399	NA	5.97463921200104	5.72499501494312	0.249644197057915	0.580180616694527	0.555907197406984	0.445660055467284	0.430287034544892	0.449075310091998	0.488490944797462	NA	NA	0.109930952839931	0.370266172747541	79.0049605495804
a5865	loss_cnaOV58	1001	AICAR	AAPK1 (AMPK) agonist	5	26	7.60090245954208	NA	8.46018134386707	8.80523579592293	-0.345054452055859	0.88183122114976	1.28663713632524	0.27856354346929	0.391293077155927	0.268183190360389	0.488496802058318	NA	NA	0.529045346945204	0.482862730478725	79.0049605495804
a5866	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1004	Vinblastine	Microtubules	8	23	-2.30258509299405	NA	-2.88647846565416	-3.46430441912856	0.577825953474406	1.89042559496444	1.79646267343629	0.317558728568828	0.30565918860471	0.321646512348144	0.488533359798644	NA	NA	0.138641678584239	0.465632606266625	79.0049605495804
a5867	gain_cnaOV26	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.25491181676615	2.59512972376311	0.659782093003034	1.34028093346459	1.72806081158515	0.38680898314263	0.492271490647497	0.38180490442221	0.488543647722189	NA	NA	0.639371858992004	0.492919375634691	79.0049605495804
a5868	loss_cnaOV59	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	2.46571186620045	1.61353753106127	0.85217433513918	1.79589532631188	1.55911394213202	0.537564802509089	0.47451225171861	0.546576046888445	0.488603292422844	NA	NA	0.0408216494767017	0.422757087351919	79.0049605495804
a5869	SMARCA4_mut	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	4.0687106801304	3.64139056854383	0.427320111586569	1.4406958090777	1.0206121135642	0.40548847803788	0.296606756883766	0.418690025238162	0.488845411241053	NA	NA	0.830640293286612	0.661875955303346	79.0207572107104
a5870	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	341	EX-527	SIRT1	7	24	2.99573227355399	NA	5.8945539901014	5.73795136311977	0.156602626981635	0.475727919843484	0.586462709814905	0.277008818369632	0.329185276813599	0.267029129662926	0.488930962716111	NA	NA	0.109936942145264	0.482497935007199	79.0207572107104
a5871	gain_cnaOV95_(MECOM)	1241	CHIR-99021	GSK3B	8	24	2.30258509299405	NA	3.45567022341567	3.75671236420154	-0.301042140785866	0.893595533728507	1.09704117207935	0.285865027776781	0.336888591564211	0.274412800948268	0.489020747658145	NA	NA	0.830641422885948	0.449280818003524	79.0207572107104
a5872	ARID1A_mut	1032	Afatinib	ERBB2, EGFR	9	22	-0.693147180559945	NA	0.0447991531806978	0.484853561109321	-0.440054407928623	1.30032741007086	1.80003580582762	0.262386463879828	0.338418158780982	0.244469808047122	0.489034115803219	NA	NA	0.836869678317889	0.455778712763155	79.0207572107104
a5873	gain_cnaOV96	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.55516080632326	2.94481393105053	0.610346875272731	0.973676062334015	1.20577922873426	0.515547645984529	0.626847982489842	0.506184598911551	0.489276601177414	NA	NA	0.0879173918403911	0.314536945182989	79.0464777053431
a5874	KRAS_mut	1030	KU-55933	ATM	7	26	2.30258509299405	NA	3.86831496714264	4.22710083874287	-0.358785871600234	1.01266982791121	1.03057978566555	0.349306491611248	0.354296989711135	0.348139830210749	0.489451718385524	NA	NA	0.528880628463992	0.427215563808614	79.0613074391174
a5875	loss_cnaOV44	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.21355081083015	3.89802512213288	0.315525688697269	0.762789858510252	0.727039075111889	0.432536873078542	0.413646937196437	0.433987249789443	0.489754879201213	NA	NA	0.955699137213033	0.553736516424291	79.0968115327363
a5876	loss_cnaOV35	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.39007323317653	5.09658095933833	0.293492273838204	0.77526924121427	0.545346623515563	0.504905567852717	0.378568190553414	0.538175650462845	0.490002552468324	NA	NA	0.0117341002971984	0.456398833401361	79.0995115793651
a5877	PIK3R1_mut	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	4.75515627565311	5.11882834502897	-0.363672069375863	0.837920532982907	0.563807859864901	0.598593423453004	0.434017374035733	0.645028378041779	0.490024287259118	NA	NA	0.109889096151597	0.396655507394996	79.0995115793651
a5878	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	222	BX-912	PDPK1 (PDK1)	7	25	2.32630161961136	NA	3.68336899738769	3.33335068677005	0.35001831061764	1.31160107930617	1.19897545453414	0.286353121123308	0.266863390203062	0.291931172814241	0.490168786293053	NA	NA	0.325793562377833	0.540837138248953	79.0995115793651
a5879	loss_cnaOV59	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.06002978367332	2.4411767366341	-0.38114695296078	1.44825676753767	0.866994624441999	0.404867336911722	0.263176365893188	0.439618588415225	0.490170516288958	NA	NA	0.7342914973696	0.639976364561802	79.0995115793651
a5880	SMAD4_mut	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	5.00645229699655	4.48476637075512	0.521685926241426	1.48407819090558	0.971161352476879	0.514755092626545	0.351521860127259	0.537177395816774	0.490274593827356	NA	NA	0.190488367398339	0.60731265558631	79.0995115793651
a5881	loss_cnaOV43_(NF1)	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.31024374249653	2.86432861140093	0.445915131095603	1.06785900634307	0.821429341167064	0.525849603765288	0.417578658274991	0.542852694380333	0.490378093467473	NA	NA	0.328529081231657	0.549944014445181	79.0995115793651
a5882	loss_cnaOV44	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.31024374249653	2.86432861140093	0.445915131095603	1.06785900634307	0.821429341167064	0.525849603765288	0.417578658274991	0.542852694380333	0.490378093467473	NA	NA	0.328529081231657	0.549944014445181	79.0995115793651
a5883	PIK3CA_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	0.583287264970219	0.94932295850261	-0.366035693532391	0.770036928495337	1.33980239978277	0.293567135873655	0.475348233295291	0.273201252357615	0.490438520486912	NA	NA	0.844586936762119	0.367525827278156	79.0995115793651
a5884	ARID1A_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	9	24	0.693147180559945	NA	2.64921371947917	2.85361092705207	-0.204397207572895	0.840760355464696	1.00520548285059	0.211711139634044	0.243109949516974	0.203338731294283	0.490627483399125	NA	NA	0.966128727652189	0.563884188186607	79.1088010075336
a5885	gain_cnaOV4_(KRAS)	1007	Docetaxel	Microtubules	5	26	-4.38202663467388	NA	-4.2920943040759	-4.7171289626695	0.425034658593599	1.86189763545504	1.34064241313987	0.298494117699869	0.228280357899334	0.317038051629398	0.49069404016366	NA	NA	0.134663794520434	0.647709580527571	79.1088010075336
a5886	loss_cnaOV34	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	2.30915100406169	2.57773988143248	-0.268588877370792	1.03370766279392	1.03971928212807	0.258520650039303	0.259830595281499	0.258328264164776	0.490785016224336	NA	NA	0.394236506229931	0.613584544037427	79.1088010075336
a5887	loss_cnaOV33_(ZFHX3)	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	0.555842504138962	0.883599171975303	-0.327756667836341	1.64517481999138	1.31675370256273	0.242418639708274	0.199223002840548	0.248912660885968	0.490895733152981	NA	NA	0.162531509453794	0.724253162236092	79.1088010075336
a5888	loss_cnaOV54	223	ZSTK474	PI3K	10	22	1.63315443905142	2.32630161961136	0.590852126830342	0.834360881975036	-0.243508755144694	1.10650979968324	1.02501413126282	0.231885027496773	0.220069225970166	0.237566241984089	0.490912993315739	NA	NA	0.77149054499195	0.563098382535031	79.1088010075336
a5889	SMAD4_mut	304	SB52334	ALK5	3	29	2.99573227355399	NA	3.89418449585262	4.41551523297322	-0.521330737120596	0.479162770563684	1.08932980541864	0.491988614081012	1.08800342837008	0.478579337981341	0.491034236566878	NA	NA	0.3508809488641	0.193450387475322	79.1144232586617
a5890	loss_cnaOV58	290	KIN001-260	IKK	5	26	2.99573227355399	NA	4.6203935648367	4.89444889357321	-0.274055328736516	1.13796908128331	0.860137128935338	0.3033087897838	0.240828448895518	0.318618182516707	0.491214459632809	NA	NA	0.664719793255907	0.631351885384042	79.1144232586617
a5891	loss_cnaOV42	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.29170356638457	3.87731034258334	0.414393223801238	1.67901082267005	1.23696952676717	0.322133158827281	0.246807952757712	0.335006816929644	0.491282143372915	NA	NA	0.572416353846503	0.662439144904597	79.1144232586617
a5892	loss_cnaOV33_(ZFHX3)	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.83601703442301	4.38769396911062	0.448323065312387	1.1415465521609	0.991037396224934	0.445389357504751	0.392733055400788	0.452377546014047	0.491286935548278	NA	NA	0.374035499700365	0.499966925033077	79.1144232586617
a5893	loss_cnaOV87, loss_cnaOV88	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.51591976734422	3.96154807414097	0.55437169320325	0.80932910560857	1.06043096393462	0.5302107041075	0.684976839905434	0.522779617021283	0.491364787902497	NA	NA	0.104039796217687	0.360203802645256	79.1144232586617
a5894	TP53_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	22	10	2.32630161961136	NA	5.17805692827387	5.06407996459923	0.113976963674637	0.663767880262834	0.358760881932047	0.193480481006402	0.171712080478352	0.317696185439263	0.49144892098831	NA	NA	0.0117382874590875	0.534686061454916	79.1145443159561
a5895	loss_cnaOV39	203	BMS-345541	IKBKB	9	23	2.77258872223978	NA	3.20098796359364	3.3056181375915	-0.104630173997862	1.31570661094267	0.932906630177155	0.0997676136593496	0.0795239403128762	0.112155033111934	0.491581071373996	NA	NA	0.091324335032744	0.831253790764902	79.1223939530282
a5896	BRCA1_mut	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	4.06583995239786	3.64168754037823	0.424152412019622	0.733912712440847	1.07317054537505	0.402438329938049	0.577933049570671	0.395232998005355	0.491940647513555	NA	NA	0.83066013448802	0.432367885796425	79.1668400138212
a5897	MLL2_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.51074216702281	-2.18485921781516	0.674117050792354	0.295865973513762	1.32979233016612	0.523230767401893	2.27845413511533	0.506934079480021	0.492100677154289	NA	NA	0.606876344251199	0.039183083479076	79.168398184286
a5898	gain_cnaOV51_(MYC)	1028	VX-702	p38	8	23	0.693147180559945	NA	3.56664851738255	3.24360251006992	0.323046007312631	0.658719085229938	0.991273210709695	0.350356544431564	0.490415435890802	0.325889980504313	0.492263464479699	NA	NA	0.517252496362079	0.312771094280079	79.168398184286
a5899	loss_cnaOV85	203	BMS-345541	IKBKB	7	25	2.77258872223978	NA	3.16434331481218	3.30750822533048	-0.143164910518305	1.04557440495338	1.04870891188558	0.136596951997171	0.136924651024418	0.136515394210672	0.492333272968507	NA	NA	0.0913332066217805	0.755783822576044	79.168398184286
a5900	loss_cnaOV59	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	4.81836374200637	4.23748050086743	0.580883241138946	1.63578921728783	1.2656345121715	0.44476376142051	0.355108858158425	0.458966024987972	0.492634068533785	NA	NA	0.37021821164129	0.53718709635142	79.168398184286
a5901	loss_cnaOV35	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	1.94488852738766	2.38207264771789	-0.43718412033023	1.10003037252631	1.25105245211804	0.354211884347907	0.397429135821223	0.349453070165102	0.492667562117964	NA	NA	0.387507735307762	0.579745588066382	79.168398184286
a5902	PIK3CA_mut	1039	SL 0101-1	RSK, AURKB, PIM3	7	26	2.30258509299405	NA	4.79523866728155	4.97600807488538	-0.18076940760383	0.672156255102173	0.8540599027466	0.219914026027412	0.268939560156815	0.211658932848256	0.492704063486874	NA	NA	0.945877668705816	0.5636771974541	79.168398184286
a5903	PIK3R1_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	5	28	2.30258509299405	NA	3.22537164899337	2.55327746136518	0.672094187628192	1.07111943009855	1.77298677891382	0.39562958577243	0.62746895326729	0.37907456255254	0.492840141384784	NA	NA	0.639425091651443	0.281340241846592	79.168398184286
a5904	SMARCA4_mut	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	2.83527398664649	3.43094525273022	-0.595671266083735	1.14513193595603	1.70444982403596	0.356051971314543	0.520176974705041	0.349480083064721	0.493010352723335	NA	NA	0.629117060301717	0.475728331421157	79.168398184286
a5905	loss_cnaOV85	279	BIX02189	MAP2K5 (MEK5)	7	25	2.99573227355399	NA	4.22972464492417	4.48759136678423	-0.257866721860055	0.949542929631502	0.671726885635328	0.350490540337937	0.27156931383832	0.383886259988182	0.493123591427894	NA	NA	0.523574543462535	0.520535658097607	79.168398184286
a5906	loss_cnaOV58	152	CP466722	ATM	5	27	2.77258872223978	NA	2.91121230278624	2.5979730520923	0.313239250693939	0.819307071162788	0.811048578924256	0.385689208508482	0.382322161884163	0.386215152623049	0.49316637993574	NA	NA	0.555173884967394	0.463786990549638	79.168398184286
a5907	gain_cnaOV51_(MYC)	1033	Vismodegib	SMO	8	23	2.30258509299405	NA	4.83609160913713	4.93697870287383	-0.100887093736696	0.800315029058828	0.88615751753633	0.11646872841396	0.126059226771412	0.113847811185058	0.493194210243172	NA	NA	0.153452580377958	0.769854036141833	79.168398184286
a5908	gain_cnaOV96	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	4.44332016049557	3.80225077571512	0.641069384780453	1.41992261600161	1.60701935793848	0.403521605191164	0.45148191708197	0.398918271652203	0.493394541367905	NA	NA	0.715069083530107	0.451931481332096	79.168398184286
a5909	loss_cnaOV52, loss_cnaOV53	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	2.26470543014417	2.50249693657064	-0.237791506426466	1.75433941276594	1.55605160002096	0.148835583513856	0.135544755305678	0.152817237181121	0.493446710471182	NA	NA	0.226163615169668	0.793932682493707	79.168398184286
a5910	loss_cnaOV82	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.19355964410926	-0.385179282448305	0.578738926557564	1.33174812919204	1.41341179515697	0.410952670783022	0.434570857560492	0.409462358061962	0.493455751570288	NA	NA	0.888771613826319	0.536837648948699	79.168398184286
a5911	loss_cnaOV36	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.500400623966514	0.383486485912155	-0.883887109878669	0.453890698119802	1.90456234369371	0.480559677691125	1.94735673927685	0.464089355124212	0.493499580121905	NA	NA	0.485182791427956	0.070749171864891	79.168398184286
a5912	gain_cnaOV94	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	-0.243774278407269	-0.630429174874073	0.386654896466804	1.13227154712135	1.96218278112077	0.205272097724541	0.341486013182811	0.19705345505374	0.493515742753602	NA	NA	0.0420019032948738	0.657351471294148	79.168398184286
a5913	KRAS_mut	225	Genentech Cpd 10	AURKA, AURKB	7	25	2.32630161961136	NA	2.27586668358261	3.0032725385849	-0.727405855002293	1.96682623573414	1.80981688443908	0.394837962452448	0.369837376473057	0.401922349855709	0.493675301725931	NA	NA	0.345437264271132	0.401737333654925	79.168398184286
a5914	loss_cnaOV39	1021	Axitinib	PDGFR, KIT, VEGFR	10	20	0.693147180559945	NA	2.81078715629216	2.38252576171348	0.428261394578675	0.836097985406624	1.10551560146097	0.417141790621312	0.512214360103256	0.38738611559413	0.493683553213149	NA	NA	0.19480879770145	0.2487166417306	79.168398184286
a5915	gain_cnaOV19	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	5.2745534758339	5.87905675063895	-0.604503274805047	1.6927891404535	1.25011795566832	0.470655902357304	0.357104887052324	0.48355698921377	0.493741469127698	NA	NA	0.570241875680274	0.602815945938068	79.168398184286
a5916	loss_cnaOV41	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.32064797981756	4.90585229144164	0.414795688375924	1.32745166707946	0.749295759634583	0.504576192226836	0.312475172288961	0.553580723022124	0.493956708441649	NA	NA	0.45285676812452	0.645624236578564	79.168398184286
a5917	loss_cnaOV42	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.32064797981756	4.90585229144164	0.414795688375924	1.32745166707946	0.749295759634583	0.504576192226836	0.312475172288961	0.553580723022124	0.493956708441649	NA	NA	0.45285676812452	0.645624236578564	79.168398184286
a5918	loss_cnaOV87, loss_cnaOV88	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.32064797981756	4.90585229144164	0.414795688375924	1.32745166707946	0.749295759634583	0.504576192226836	0.312475172288961	0.553580723022124	0.493956708441649	NA	NA	0.45285676812452	0.645624236578564	79.168398184286
a5919	gain_cnaOV51_(MYC)	238	CAL-101	PI3Kdelta	8	24	2.99573227355399	2.32630161961136	4.22557280701444	4.44110516650395	-0.215532359489506	0.867897194989156	1.0228609762017	0.217956645648308	0.248338582880429	0.210715204220486	0.494005827346259	NA	NA	0.510699325559498	0.570616679474771	79.168398184286
a5920	loss_cnaOV82	1262	UNC1215	LMBL3	3	30	0	NA	3.02098678324548	2.75635529666893	0.264631486576552	0.873493822638121	0.454706391763968	0.537225715667484	0.302957479169474	0.581983212397681	0.494057372068624	NA	NA	0.109097236727016	0.653823013511512	79.168398184286
a5921	loss_cnaOV52, loss_cnaOV53	1069	EHT 1864	Rac GTPases	9	24	2.30258509299405	NA	4.50498800487432	4.12595063513635	0.379037369737962	0.533098161231966	1.08232431247703	0.390436069662078	0.711008585852227	0.350206832987507	0.494188533247147	NA	NA	0.208788595716634	0.191906481523154	79.168398184286
a5922	loss_cnaOV55	1003	Camptothecin	TOP1	7	24	-2.30258509299405	NA	-3.14606894870711	-3.85015510180608	0.704086153098971	0.970880063919778	1.86291775086377	0.410111528346399	0.725204048640501	0.37794806172871	0.494346177434026	NA	NA	0.244298825480794	0.197846923425354	79.168398184286
a5923	loss_cnaOV82	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-5.06548721844492	-4.04956545796039	-1.01592176048452	1.05495681113963	2.41675654772322	0.433071858270176	0.962998437241298	0.420365783819477	0.494356360656511	NA	NA	0.927900471904567	0.243563861949302	79.168398184286
a5924	loss_cnaOV42	1262	UNC1215	LMBL3	4	29	0	NA	2.99329176563499	2.75105007542291	0.242241690212078	0.818236369739019	0.443127985327812	0.492272742983786	0.296053437821814	0.546663036939261	0.494403343796803	NA	NA	0.109101541746533	0.599441279050464	79.168398184286
a5925	gain_cnaOV4_(KRAS)	1377	Afatinib (rescreen)	ERBB2, EGFR	7	26	2.30258509299405	NA	3.05195233437558	2.54826772394472	0.503684610430859	0.80904367645237	1.85529575595266	0.295641668530372	0.622567884887871	0.271484807106792	0.494489146956142	NA	NA	0.639445315156635	0.299965058311672	79.168398184286
a5926	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.89152408273902	4.24952724149879	0.641996841240233	1.99539342796252	1.24537098696774	0.49126844139636	0.321739478662998	0.515506502045131	0.494621538931503	NA	NA	0.370252699264101	0.635840726142322	79.168398184286
a5927	TP53_mut	235	QL-XII-47	BTK, BMX	22	10	2.32630161961136	NA	1.67664972100322	1.32029494194793	0.35635477905529	1.63790849005997	1.59698214147821	0.219195596466729	0.217566964954338	0.223142619945292	0.494640601783594	NA	NA	0.078302278789036	0.568879089392527	79.168398184286
a5928	gain_cnaOV49	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	0.377543659121603	0.797649299806531	-0.420105640684928	0.88527813697673	1.05970698059039	0.4004892185788	0.4745464991597	0.396435664178487	0.494696560531429	NA	NA	0.771522563403441	0.505918395874866	79.168398184286
a5929	loss_cnaOV21, loss_cnaOV22	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.68008690442989	4.40543434382018	0.274652560609705	1.16229284126856	0.699380061662041	0.371496464981735	0.236302376524957	0.392708593889576	0.494877268378004	NA	NA	0.523602016395695	0.72422766493773	79.168398184286
a5930	loss_cnaOV52, loss_cnaOV53	1005	Cisplatin	DNA crosslinker	8	23	1.79175946922805	2.30258509299405	3.41821623099454	2.88629954416092	0.531916686833624	0.998824730451662	1.2299396964075	0.451422973466082	0.532542567896867	0.432473793948829	0.495146116168756	NA	NA	0.0879874674792497	0.241749724573551	79.168398184286
a5931	gain_cnaOV51_(MYC)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	8	24	0.246860077931526	2.32630161961136	0.651103401270618	1.12186919724597	-0.470765795975351	0.789355230175909	1.71322970442393	0.304152381981662	0.596392825408201	0.274782648677952	0.495166288128956	NA	NA	0.790635087768325	0.302245451083549	79.168398184286
a5932	SMAD4_mut	1026	17-AAG	HSP90	4	29	0	NA	-1.44492028177341	-0.404751037809585	-1.04016924396383	1.77798077880065	2.33707029510706	0.45443252639204	0.585028396463026	0.445074008317828	0.495237957660999	NA	NA	0.0608555574279652	0.345411244491279	79.168398184286
a5933	KRAS_mut	226	GSK1070916	AURKB	7	25	0.940007258491471	2.32630161961136	2.66989248964896	2.2143115512027	0.455580938446255	0.972143672104741	1.53849179122543	0.315692947456313	0.468635399806593	0.296121786963437	0.495524921651344	NA	NA	0.820625487768753	0.356429456027952	79.168398184286
a5934	loss_cnaOV33_(ZFHX3)	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.26243809741337	3.9394749097555	0.322963187657875	1.02106355075134	0.725038960626236	0.425036040227232	0.316300770329356	0.445442528190379	0.49569558966794	NA	NA	0.52483875610861	0.579187555545474	79.168398184286
a5935	gain_cnaOV18_(CCNE1)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-0.348851129715908	-0.628185674289556	0.279334544573647	0.945704111584602	2.03126831694847	0.148135422722995	0.295372031433384	0.137517304948312	0.49581418243602	NA	NA	0.0420307827145705	0.699809499712451	79.168398184286
a5936	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.87733609327343	4.46594426271463	0.411391830558806	0.854519631369459	1.00234615785709	0.4178603929324	0.481430520091746	0.410428899571298	0.495884387659182	NA	NA	0.324685519068997	0.371152261841983	79.168398184286
a5937	SMARCA4_mut	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	3.98195703124447	4.48804407160556	-0.506087040361091	0.555013805483241	1.03059492237868	0.502711303773056	0.911845859258311	0.491063005815136	0.496006487502991	NA	NA	0.374117275155218	0.252452530736025	79.168398184286
a5938	loss_cnaOV52, loss_cnaOV53	1025	SB 216763	GSK3A, GSK3B	7	16	2.30258509299405	NA	5.18764431614565	4.86034247220412	0.327301843941532	0.747214322612319	0.847305526977879	0.399170141596929	0.438029403394276	0.386285505665157	0.496015842559959	NA	NA	0.452907521432536	0.370755017754355	79.168398184286
a5939	SMARCA4_mut	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.32423483090355	4.69542826082039	0.628806570083162	0.26644110219412	1.26585721389699	0.513970296410366	2.36002090107342	0.496743679444979	0.496030827249529	NA	NA	0.424022034430627	0.0416587218087419	79.168398184286
a5940	loss_cnaOV20	306	TG101348	JAK2	5	27	2.32630161961136	NA	3.26570993643423	2.74227133709744	0.523438599336786	1.06682981901202	1.43849321511633	0.375312936122767	0.490648639556718	0.363879783259496	0.496309752953843	NA	NA	0.626842219196738	0.374145879350388	79.168398184286
a5941	ARID1A_mut	157	JNK-9L	JNK	5	14	1.63315443905142	NA	0.050418163673188	-0.0607558693440889	0.111174033017277	0.989360427893876	1.02854056053478	0.109052184671229	0.112369597451903	0.108089109251533	0.496424419534497	NA	NA	0.189117051711654	0.836794584695035	79.168398184286
a5942	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	2.84806601671017	3.47270015576167	-0.624634139051501	1.84045807590191	1.63773232374266	0.374888114293543	0.339390582828355	0.381401850593047	0.496530480144014	NA	NA	0.629162619995923	0.508770861739913	79.168398184286
a5943	loss_cnaOV82	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.24278008403331	2.5963428970364	0.646437186996919	2.62471518828818	1.62376337369764	0.378885453183383	0.246288507751777	0.398110462071115	0.496636527701045	NA	NA	0.639471480083782	0.713527846492206	79.168398184286
a5944	KRAS_mut	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	7.48256181496886	6.55046925694756	0.932092558021299	1.67276330667168	1.46699552689198	0.624443789389653	0.557217243051498	0.63537518754134	0.496649908368273	NA	NA	0.335424374762844	0.442283443461105	79.168398184286
a5945	RB1_mut	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	2.98002355951896	3.8244682106685	-0.844444651149535	0.791635582080681	1.59222232393478	0.543724106962829	1.06670881181219	0.530355992662319	0.496660147317098	NA	NA	0.164481916699938	0.195782332956644	79.168398184286
a5946	gain_cnaOV96	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.48576165166617	3.89317362261037	0.592588029055795	0.928017473207685	1.18300007993342	0.511192670587218	0.63855266324622	0.500919686403696	0.496913145028976	NA	NA	0.0823273898985279	0.307833555822145	79.168398184286
a5947	gain_cnaOV72_(ASXL1)	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	9.11422262793278	8.69556099635557	0.418661631577203	0.884649436746854	1.27154085216779	0.338410542878315	0.473251453272563	0.329255352561774	0.497009722387972	NA	NA	0.5291830347469	0.444827908577465	79.168398184286
a5948	gain_cnaOV72_(ASXL1)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.72860958108707	2.8887965412969	-0.160186960209836	0.498837855250363	0.845258830280402	0.198324809303291	0.321120296953886	0.189512317968564	0.497122680029369	NA	NA	0.0192941150626621	0.576036264768266	79.168398184286
a5949	gain_cnaOV19	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	-0.248926056461168	-0.629463216488967	0.380537160027799	1.13208845873997	1.96239828379322	0.202004384349145	0.336137301895421	0.193914335927893	0.497176221711583	NA	NA	0.0420477968126893	0.662295738881499	79.168398184286
a5950	loss_cnaOV59	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.23999642625881	2.32347293650765	0.916523489751166	2.12671080385116	1.49160316394709	0.584986698842432	0.43095821401362	0.614455313520424	0.497382237485398	NA	NA	0.226265943334134	0.537612827306762	79.168398184286
a5951	loss_cnaOV57_(ZNRF3)	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.62847962158207	4.25085970971878	0.377619911863299	0.810469416924186	0.795909044268367	0.473547571001893	0.465927404511332	0.474451087825523	0.497432953142978	NA	NA	0.224292338185973	0.433650645839269	79.168398184286
a5952	gain_cnaOV50	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	2.02830168813092	1.49336479509004	0.534936893040884	0.859530892957452	1.08772927081941	0.500830960349271	0.622359123358891	0.491792312105294	0.497631232271691	NA	NA	0.452971572238399	0.403245751178941	79.168398184286
a5953	loss_cnaOV82	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.52791046727381	4.03810272134151	0.4898077459323	1.70298784361687	1.06607741622618	0.43738108641258	0.287616701298366	0.459448571442568	0.497919568092798	NA	NA	0.819329098759889	0.670309609596149	79.168398184286
a5954	loss_cnaOV41	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.83808553842904	1.23443529947927	0.603650238949769	0.897522555609694	1.24038449249037	0.49868817256627	0.672573892630146	0.486663806750597	0.498079087244948	NA	NA	0.0969630608626474	0.288513870121352	79.168398184286
a5955	loss_cnaOV42	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.83808553842904	1.23443529947927	0.603650238949769	0.897522555609694	1.24038449249037	0.49868817256627	0.672573892630146	0.486663806750597	0.498079087244948	NA	NA	0.0969630608626474	0.288513870121352	79.168398184286
a5956	gain_cnaOV4_(KRAS)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	6	13	-0.669430653942629	NA	-4.36560761627632	-3.80562196733253	-0.559985648943792	1.67728645117489	1.87906150646699	0.307340451676979	0.333864050801542	0.298013474820565	0.498156268341472	NA	NA	0.589215397644757	0.528633969820433	79.168398184286
a5957	loss_cnaOV35	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.57073216617661	2.32285491141494	0.24787725476167	0.674354412185962	0.89959099027731	0.283962080288635	0.367577123071177	0.275544394553417	0.498460046487716	NA	NA	0.607314863554186	0.499167428878121	79.168398184286
a5958	loss_cnaOV54	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	22	1.38629436111989	NA	0.9145879881415	1.36679506468057	-0.452207076539073	1.47367320842376	1.09383990765116	0.367869964807216	0.306857092844046	0.413412486942549	0.498466948855431	NA	NA	0.266182199826019	0.381123822335477	79.168398184286
a5959	loss_cnaOV57_(ZNRF3)	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.89476710527241	1.57443239109043	0.320334714181983	1.18166641346961	0.599611902821974	0.470666092918226	0.271087263317755	0.53423674992838	0.498566110168943	NA	NA	0.208311139408291	0.628928717811593	79.168398184286
a5960	SMARCA4_mut	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	3.22440725313694	3.95574392238856	-0.731336669251625	0.333111032585996	1.64378056509858	0.460395499679292	2.19547417440406	0.444911373683121	0.498614960702454	NA	NA	0.715124581241693	0.06123809695954	79.168398184286
a5961	gain_cnaOV50	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	1.30653146668779	1.60707739196854	-0.300545925280756	0.153868652803235	1.11305744672677	0.282927414396865	1.95326286287233	0.270018341069985	0.498648189031297	NA	NA	0.285884980915635	0.257759939964488	79.168398184286
a5962	gain_cnaOV72_(ASXL1)	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	5.21270389248322	4.68866223058328	0.524041661899941	0.74804437628853	1.26859374642742	0.427773538734681	0.700548895909099	0.41308863722191	0.498650099702223	NA	NA	0.424068745840833	0.285322016990782	79.168398184286
a5963	loss_cnaOV35	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.62163395923939	4.82718861317552	-0.205554653936129	0.755434803941188	0.650277635517956	0.308984087945395	0.272101116951096	0.31610291160083	0.498959321249502	NA	NA	0.761708010115988	0.592262414839447	79.168398184286
a5964	gain_cnaOV95_(MECOM)	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-2.34639276402305	-2.89043381761206	0.544041053589011	1.49608297991794	1.11774448047415	0.446891437092448	0.363643635340903	0.486731147496455	0.499088437511432	NA	NA	0.377421141330798	0.487327854755693	79.168398184286
a5965	gain_cnaOV72_(ASXL1)	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	-1.55349077673223	-0.96792330060876	-0.585567476123473	1.22512641072774	2.06900270750573	0.296129384374685	0.477964943858848	0.283019192773024	0.499116197818763	NA	NA	0.442833562118812	0.409835645287285	79.168398184286
a5966	gain_cnaOV72_(ASXL1)	155	AP-24534	ABL	4	15	-0.669430653942629	NA	1.24868428089306	0.665848590018144	0.582835690874919	1.24921523162026	1.25063656328498	0.466124666559729	0.466561466849047	0.466031226005431	0.499179537146871	NA	NA	0.583014534244677	0.446832385452983	79.168398184286
a5967	gain_cnaOV51_(MYC)	291	KIN001-266	MAP3K8 (COT)	8	24	2.99573227355399	NA	3.53738989390143	3.22412495836433	0.313264935537094	0.879783748222604	1.16777256022739	0.282910085556722	0.356070382261519	0.268258517288756	0.499184891975966	NA	NA	0.950844215349824	0.435804628522648	79.168398184286
a5968	ARID1A_mut	344	THZ-2-49	CDK9	8	24	2.99573227355399	NA	1.80172348181427	2.84907232006016	-1.04734883824589	2.07039266272929	2.37377813858105	0.454073918932781	0.505869662842228	0.441215976010273	0.499244705489207	NA	NA	0.385191399114385	0.253113807967359	79.168398184286
a5969	gain_cnaOV48_(SOX17)	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.08209324337828	4.32288753280716	-0.240794289428877	0.754951281347833	0.808304287103225	0.299220601015391	0.318953415111743	0.297900547195943	0.499321533554979	NA	NA	0.224325397140544	0.644423334660844	79.168398184286
a5970	gain_cnaOV50	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	3.10457261632765	3.45353784591624	-0.348965229588588	0.866412606311233	1.25925546374386	0.28471840067937	0.402770258704238	0.277120282290529	0.499391131984674	NA	NA	0.325959826234707	0.511504956333566	79.168398184286
a5971	loss_cnaOV21, loss_cnaOV22	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.3395868515469	4.50555038036274	-0.165963528815839	0.857960006839725	0.665335392605032	0.243930232078637	0.193439702891469	0.249443409535198	0.499486334661727	NA	NA	0.0530339515339023	0.77295028826273	79.168398184286
a5972	loss_cnaOV59	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.59175269998848	5.73269066147342	-0.140937961484942	0.514255441057102	0.47548439397251	0.293925339305719	0.274062168783729	0.296409226615102	0.499653304809608	NA	NA	0.380947868961273	0.633710293220253	79.168398184286
a5973	BRCA1_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	2.14451951293863	2.72553617625646	-0.581016663317834	0.821856553668397	1.77448746930314	0.340630274025937	0.706956293923116	0.327427876143868	0.499761870564505	NA	NA	0.639509218962039	0.303047621719507	79.168398184286
a5974	gain_cnaOV19	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-1.03435627663415	-1.67313017788935	0.638773901255201	1.03380809865457	1.33924745891399	0.488724135208493	0.617884404355623	0.476964803631728	0.500053708279128	NA	NA	0.62091889890416	0.411845749962983	79.168398184286
a5975	loss_cnaOV81_(RB1)	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	4.15750489723506	3.75005672981582	0.407448167419239	0.829528481464527	1.05026971189993	0.395455599180268	0.49118044349712	0.387946222577596	0.500063711961463	NA	NA	0.716749566875894	0.42032881681854	79.168398184286
a5976	loss_cnaOV34	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.51369273613054	2.91653335081491	0.597159385315631	1.30469864230918	1.66399817825879	0.368457605893032	0.457699093070812	0.358870215795849	0.500098188463247	NA	NA	0.662940015714797	0.40079272356556	79.168398184286
a5977	loss_cnaOV70	152	CP466722	ATM	3	29	2.77258872223978	NA	2.37313535776217	2.67523889128058	-0.302103533518409	0.908513645513997	0.808500924070798	0.37042915430385	0.332525036921699	0.373658859902496	0.500127326475487	NA	NA	0.555276935895088	0.62817300119573	79.168398184286
a5978	gain_cnaOV94	1058	GDC0941	PI3K (class 1)	7	26	1.38629436111989	0.693147180559945	1.27924092189305	0.726656136561088	0.55258478533196	1.94185681020641	1.14430842091971	0.41350258915546	0.284565155591067	0.482898469704378	0.500159425761169	NA	NA	0.162669110563505	0.494363538260461	79.168398184286
a5979	loss_cnaOV16, loss_cnaOV17	208	SB-715992	KIF11	6	26	-2.05572501506252	NA	-0.648777701804259	-1.47169629040891	0.822918588604649	1.95394054150838	1.83810830245875	0.442925796412673	0.421158459596413	0.447698640773163	0.500185505150665	NA	NA	0.0736825656509565	0.377671628143547	79.168398184286
a5980	loss_cnaOV102	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-5.05341269716699	-4.05090707143572	-1.00250562573127	1.05883695902804	2.41720776973254	0.427251410298199	0.946798859997787	0.414737052513361	0.500225660247666	NA	NA	0.927917520695208	0.250235982938296	79.168398184286
a5981	gain_cnaOV49	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.47061984261118	-0.0212381248988383	-0.449381717712342	1.30337192030759	0.933853515078895	0.466691352181239	0.344783949009956	0.481212214181553	0.500389248598081	NA	NA	0.548296884107038	0.614336736272312	79.168398184286
a5982	loss_cnaOV16, loss_cnaOV17	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.96248270032853	1.47906685078313	0.483415849545403	2.16108827517164	0.742403203100255	0.45283767498516	0.22369093160112	0.651150005181378	0.500457760721759	NA	NA	0.453040279187572	0.687128842450659	79.168398184286
a5983	loss_cnaOV41	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.96248270032853	1.47906685078313	0.483415849545403	2.16108827517164	0.742403203100255	0.45283767498516	0.22369093160112	0.651150005181378	0.500457760721759	NA	NA	0.453040279187572	0.687128842450659	79.168398184286
a5984	loss_cnaOV42	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.96248270032853	1.47906685078313	0.483415849545403	2.16108827517164	0.742403203100255	0.45283767498516	0.22369093160112	0.651150005181378	0.500457760721759	NA	NA	0.453040279187572	0.687128842450659	79.168398184286
a5985	loss_cnaOV55	1020	Lenalidomide	TNFA	7	24	1.6094379124341	NA	4.68297595178912	4.31736830172684	0.365607650062285	0.628815607138436	0.793311038924948	0.479676824096298	0.581422671307512	0.460862930330248	0.500480839216669	NA	NA	0.0427603472841825	0.227376202273499	79.168398184286
a5986	loss_cnaOV36	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.88627670224379	4.39761210450563	0.48866459773816	1.39267246359973	0.975314710773897	0.485040351430649	0.350882645065788	0.501032735731436	0.500482051642815	NA	NA	0.374193619005096	0.6082328852055	79.168398184286
a5987	loss_cnaOV41	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	1.87722072450399	2.36087573517955	-0.483655010675564	1.60237488474034	1.20989867541749	0.385014648808462	0.301836365061312	0.399748359513388	0.500504181075183	NA	NA	0.844259575245927	0.597128634353869	79.168398184286
a5988	loss_cnaOV42	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	1.87722072450399	2.36087573517955	-0.483655010675564	1.60237488474034	1.20989867541749	0.385014648808462	0.301836365061312	0.399748359513388	0.500504181075183	NA	NA	0.844259575245927	0.597128634353869	79.168398184286
a5989	loss_cnaOV36	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.61103890249695	2.96062509486309	0.650413807633856	1.54133674437162	1.15543347416972	0.548370165365106	0.421980342718048	0.562917573511736	0.50051756874394	NA	NA	0.088050410207116	0.544242626175236	79.168398184286
a5990	NF1_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	1.88272045322987	1.20520321278939	0.677517240440482	1.73297760826122	2.39258534082178	0.290154235293734	0.390955565271422	0.283173698710273	0.500544569008885	NA	NA	0.362711117630469	0.520175400431505	79.168398184286
a5991	gain_cnaOV51_(MYC)	164	JQ12	HDAC	5	14	1.63315443905142	NA	2.30056601909564	1.61293842831186	0.687627590783774	2.4074214502695	2.1605661927167	0.309586053951489	0.285628256202002	0.318262681838574	0.500562793914758	NA	NA	0.659416149162011	0.592505931364638	79.168398184286
a5992	gain_cnaOV51_(MYC)	1170	CCT018159	HSP90	8	25	2.30258509299405	NA	3.56565402206995	3.73633675844521	-0.170682736375261	1.247422340293	1.22734500436933	0.138551618673305	0.136828346632921	0.139066632257135	0.500587386512332	NA	NA	0.1974870661883	0.741242661112519	79.168398184286
a5993	loss_cnaOV34	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.595816392316564	-1.45102547406942	0.855209081752856	2.10735590024914	1.81878532306804	0.459826875771817	0.405820906497924	0.470208919604781	0.500611379830167	NA	NA	0.0736868839939206	0.432614804217225	79.168398184286
a5994	loss_cnaOV84	279	BIX02189	MAP2K5 (MEK5)	6	26	2.99573227355399	NA	4.21507357175291	4.48105443282914	-0.265980861076228	1.03930507413234	0.658998746337038	0.361310577547407	0.255921834402937	0.403613607089011	0.500648160909175	NA	NA	0.523691268756624	0.570798780242215	79.168398184286
a5995	loss_cnaOV40	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-4.18966798611231	-4.77794485396399	0.588276867851688	3.37079228792327	1.66719363588747	0.283886138509729	0.174521838666637	0.35285455461719	0.500854009585125	NA	NA	0.348333434204562	0.755042287674363	79.168398184286
a5996	SMAD4_mut	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-1.38123140626169	-2.32073329303431	0.939501886772622	4.19568224712736	2.39562531453663	0.351726095343203	0.223921124488363	0.392173968554988	0.50094429451448	NA	NA	0.415470686701419	0.739114372642074	79.168398184286
a5997	loss_cnaOV59	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	0.663062102981244	1.23750309319693	-0.574440990215687	2.39595633508957	1.36047526607138	0.384905767987739	0.239754365220605	0.422235526467518	0.501059946530985	NA	NA	0.812793907925465	0.668447111252044	79.168398184286
a5998	gain_cnaOV4_(KRAS)	1054	PD-0332991	CDK4, CDK6	7	26	1.38629436111989	0.693147180559945	2.69483997641691	2.17358824412023	0.521251732296672	2.0371812159136	1.72767884452594	0.290916077231959	0.25586910394857	0.301706381338309	0.501141136447856	NA	NA	0.110020335775554	0.551799563655081	79.168398184286
a5999	loss_cnaOV102	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	4.52536886072221	3.81635517871871	0.709013682003496	1.67601179778247	1.58284099506604	0.446077125529678	0.423036211882035	0.447937401301584	0.501145880949491	NA	NA	0.715151131722294	0.54562875210849	79.168398184286
a6000	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	172	Embelin	XIAP	3	16	3.46573590279973	NA	2.711149535307	3.17051296540009	-0.459363430093092	1.26831106265437	0.903656074039269	0.481603799478444	0.362185148122669	0.508338784289663	0.501148262233914	NA	NA	0.669986317135532	0.600725509396896	79.168398184286
a6001	loss_cnaOV36	219	AT-7519	CDK9	3	29	2.32630161961136	NA	0.980930829819445	1.55116738291357	-0.570236553094129	1.11406597854788	1.744966564947	0.333439895518353	0.511851689284505	0.326789386426695	0.501328084134886	NA	NA	0.315362034226255	0.484133947077423	79.168398184286
a6002	loss_cnaOV87, loss_cnaOV88	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	3.32717818345214	3.94473275128336	-0.617554567831217	0.485187809146997	1.64566078891941	0.387666655019707	1.27281550811619	0.375262369978884	0.501342484417335	NA	NA	0.715153184557993	0.174346514004364	79.168398184286
a6003	gain_cnaOV94	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.69058252564746	2.34433212325641	0.346250402391053	1.30547414191297	0.939598172762676	0.349858174935211	0.265229613727682	0.368509020588005	0.501409758434623	NA	NA	0.408759771544437	0.697293022698423	79.168398184286
a6004	loss_cnaOV39	1017	Olaparib	PARP1, PARP2	10	21	1.6094379124341	NA	4.31955624334272	3.80300818970084	0.516548053641883	1.03525700581604	1.19875872428667	0.448974639135357	0.498956346820098	0.430902435308039	0.501552503702911	NA	NA	0.0823795012694402	0.231710610950022	79.168398184286
a6005	TP53_mut	231	FMK	RSK	13	7	2.99573227355399	2.32630161961136	5.32037527397607	5.09888993468516	0.221485339290907	0.869225679157582	0.38829745114675	0.297581267059341	0.254807634658886	0.570401218542123	0.501598404598582	NA	NA	0.125478601070468	0.442989457886016	79.168398184286
a6006	gain_cnaOV48_(SOX17)	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.56641722683745	2.73151365669672	-0.16509642985927	0.339497292687589	0.585057678503711	0.288642084079205	0.486296749385847	0.282188296855629	0.501696779057413	NA	NA	0.135010606527249	0.508942139277445	79.168398184286
a6007	loss_cnaOV38	255	CP724714	ERBB2	8	24	2.32630161961136	NA	4.59365171130772	4.35554216508716	0.238109546220553	1.20542729807071	0.860640197099065	0.250030478962112	0.197531237762449	0.276665611277677	0.501836570912317	NA	NA	0.786128556922795	0.617290099230964	79.168398184286
a6008	loss_cnaOV16, loss_cnaOV17	1527	GDC0941 (rescreen)	PI3K	5	26	1.38629436111989	NA	0.120536697206853	0.432616750715001	-0.312080053508148	0.694072014998956	0.941350300761539	0.342478000528276	0.449636416343076	0.331523826205484	0.502231912062302	NA	NA	0.909508541529543	0.415425511327834	79.168398184286
a6009	loss_cnaOV81_(RB1)	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.91196125561564	4.47535430344532	0.436606952170322	0.534465932472394	1.0218788453763	0.443118758189204	0.816903240493956	0.427259018176019	0.50226944350264	NA	NA	0.324795179209029	0.226922718839716	79.168398184286
a6010	gain_cnaOV49	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	9.38907830395599	8.68984042094713	0.699237883008861	1.72127700914992	1.70934964688276	0.408869224641906	0.406232047074277	0.409066620327808	0.502304145101534	NA	NA	0.921668220641193	0.561116510253077	79.168398184286
a6011	loss_cnaOV87, loss_cnaOV88	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.24431730407805	5.56920391891228	-0.324886614834228	2.74825711067157	0.705183516812758	0.330271098158389	0.118215509594311	0.460712150934312	0.502319099619456	NA	NA	0.303450232317643	0.856960016415288	79.168398184286
a6012	PTEN_mut	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	1.53876420622324	2.65060656930715	-1.11184236308391	1.38949742395004	1.56114979684079	0.723561370335492	0.800175908151871	0.712194541058063	0.502367525852277	NA	NA	0.226393636030704	0.218134172743003	79.168398184286
a6013	gain_cnaOV50	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	-0.481173736335087	-0.0565145682872698	-0.424659168047818	2.01250514182286	1.1439265282011	0.336545713697305	0.211010227612723	0.371229408164546	0.502468735205231	NA	NA	0.766772825159941	0.705528894857638	79.168398184286
a6014	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	2.77956606904788	2.34447611197862	0.435089957069262	1.44873379927742	1.46091419021731	0.298316118575766	0.300324295109475	0.297820337417998	0.502480430957607	NA	NA	0.239412428169518	0.499747260181661	79.168398184286
a6015	loss_cnaOV43_(NF1)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	1.83568296334157	1.05368227765135	0.782000685690215	2.7560497414551	1.33906717514969	0.496994702508749	0.283739685074532	0.583989138261715	0.502507242509722	NA	NA	0.533321911235236	0.674544788838677	79.168398184286
a6016	PTEN_mut	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.18186903727297	3.52315760827452	-0.341288571001545	1.46855100851558	0.822272129300011	0.377026603989792	0.232398172772033	0.415055501506635	0.502555165988262	NA	NA	0.793915053526257	0.677643364515777	79.168398184286
a6017	gain_cnaOV18_(CCNE1)	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	-0.53814545697576	-1.13388575614981	0.595740299174049	2.99503037813563	1.83179315735804	0.301011789599488	0.198909601559664	0.32522247218855	0.502579674140642	NA	NA	0.442891607500463	0.721792743269843	79.168398184286
a6018	gain_cnaOV26	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.20760307495522	2.93227129260401	0.275331782351208	0.46545417962291	0.616711718701813	0.458201932403321	0.591533591070703	0.446451354825535	0.502779112927361	NA	NA	0.849102480262197	0.431265704080193	79.168398184286
a6019	loss_cnaOV1	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.78800522440323	3.27731809285076	0.510687131552471	0.440856727825983	1.26887665392336	0.414813436195747	1.1583970467477	0.402471847813915	0.502780107266406	NA	NA	0.993601754789471	0.187255248680547	79.168398184286
a6020	loss_cnaOV58	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	4.22611625004077	3.8609616231014	0.365154626939375	1.21131355552492	1.22585540128867	0.29836309393348	0.301453430677688	0.297877405895923	0.502781311579315	NA	NA	0.698300093412049	0.561611112839858	79.168398184286
a6021	gain_cnaOV94	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	7	26	1.6094379124341	NA	2.13688831192568	2.39964485525122	-0.262756543325537	1.58407334281116	1.55640440453598	0.168239781038896	0.165873975796624	0.16882279602895	0.502828839480005	NA	NA	0.241476747864172	0.704549660565415	79.168398184286
a6022	loss_cnaOV84	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	2.04539715846537	1.44768107772014	0.597716080745224	0.937624858279804	1.30755456771126	0.479865387947787	0.637478918638967	0.457125152177368	0.502945568306675	NA	NA	0.162987059323931	0.280728974711299	79.168398184286
a6023	loss_cnaOV85	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	2.04539715846537	1.44768107772014	0.597716080745224	0.937624858279804	1.30755456771126	0.479865387947787	0.637478918638967	0.457125152177368	0.502945568306675	NA	NA	0.162987059323931	0.280728974711299	79.168398184286
a6024	loss_cnaOV85	1005	Cisplatin	DNA crosslinker	7	24	1.79175946922805	2.30258509299405	3.43656622013878	2.90311065927858	0.533455560860201	1.33509000066795	1.13647905449869	0.451959901921735	0.399565243237019	0.469393218245901	0.503098965030084	NA	NA	0.0880802619810892	0.36272161949546	79.168398184286
a6025	gain_cnaOV4_(KRAS)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	5	26	0.693147180559945	NA	0.225025659773752	-0.231393362157898	0.456419021931651	2.02883410575909	1.5358283278486	0.282995473908119	0.224966161913412	0.297181015387967	0.503126643459426	NA	NA	0.1000612698824	0.653513391178445	79.168398184286
a6026	gain_cnaOV51_(MYC)	207	AS601245	JNK 	5	13	2.07944154167984	NA	1.67752560136184	2.11498784132556	-0.437462239963717	0.869789162030415	1.01554801778853	0.445871158858383	0.502952047531284	0.430764702703415	0.503147042551324	NA	NA	0.478058683538034	0.387407873051388	79.168398184286
a6027	loss_cnaOV84	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-1.87614148096281	-2.78469523877613	0.908553757813321	2.89756838656068	1.60055700410476	0.458041604045792	0.313557313099949	0.567648484548355	0.503153463954328	NA	NA	0.343764063929811	0.535587001421091	79.168398184286
a6028	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.598752838131442	-1.45048168780741	0.851728849675963	2.10718786300123	1.81908023876466	0.457900342404225	0.40420166831393	0.468219505399263	0.503159770201269	NA	NA	0.0737125976250345	0.434348823421117	79.168398184286
a6029	gain_cnaOV18_(CCNE1)	157	JNK-9L	JNK	4	15	1.63315443905142	NA	0.156688736414594	-0.0816830865406455	0.23837182295524	1.18485209830733	0.975501962972538	0.234713397074598	0.20118276643623	0.244358117157321	0.503284028035595	NA	NA	0.189313758459758	0.729281126788411	79.168398184286
a6030	loss_cnaOV82	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.43631212659421	5.1120384720081	0.324273654586111	0.980700071956998	0.54414442762576	0.555739286735094	0.330655277651831	0.595933061376737	0.503368174436873	NA	NA	0.011772063085952	0.626624333414528	79.168398184286
a6031	SMAD4_mut	341	EX-527	SIRT1	3	28	2.99573227355399	NA	6.03845364775315	5.7449053465116	0.293548301241552	0.658978719255466	0.554423088109528	0.522087914853059	0.445459455159966	0.529466228115595	0.503623283208908	NA	NA	0.110131960583867	0.525164295250019	79.168398184286
a6032	loss_cnaOV59	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.29566984992934	2.97145485956185	0.324214990367494	1.77892115453258	0.978191586683727	0.298764405137309	0.18225371570933	0.33144324157055	0.503651089705101	NA	NA	0.43384950175038	0.7430210241944	79.168398184286
a6033	gain_cnaOV19	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.96624184107999	4.48447980997123	0.481762031108762	1.19403790410489	0.969913247248457	0.488646272310743	0.403472979754286	0.496706311080368	0.503695835433559	NA	NA	0.324819353784853	0.560875656945068	79.168398184286
a6034	KRAS_mut	1025	SB 216763	GSK3A, GSK3B	4	19	2.30258509299405	NA	4.75753256352009	5.00257155337922	-0.245038989859123	0.661144573815218	0.854100947477873	0.295480784642574	0.370628451875653	0.286896988678813	0.503737581117601	NA	NA	0.453094696924292	0.549906249777619	79.168398184286
a6035	gain_cnaOV96	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	2.00788632697654	1.48183371617483	0.526052610801713	0.867756040295287	1.07314000327753	0.502194826248666	0.606221779364051	0.4901994233698	0.503775369608798	NA	NA	0.286008840792819	0.336856226855786	79.168398184286
a6036	gain_cnaOV50	1030	KU-55933	ATM	4	29	2.30258509299405	NA	3.87398138851403	4.18920348356059	-0.31522209504656	0.283574525277378	1.08273451046591	0.305215391300002	1.11160230185778	0.291135169332431	0.50403188148653	NA	NA	0.529097666504378	0.215539802411173	79.168398184286
a6037	loss_cnaOV16, loss_cnaOV17	1022	AZD7762	CHEK1, CHEK2	6	25	0.693147180559945	NA	-0.515362362512765	-0.88745253075189	0.372090168239125	1.10229350138699	0.720052034064779	0.465631652195474	0.337559976332015	0.516754554721041	0.504054739990704	NA	NA	0.0783209343943052	0.460651776128891	79.168398184286
a6038	loss_cnaOV58	1004	Vinblastine	Microtubules	5	26	-2.30258509299405	NA	-2.61579654100137	-3.44968641000705	0.833889869005683	2.1994546570253	1.74047530399514	0.460531233805444	0.379134830691847	0.479116174237892	0.504162958448109	NA	NA	0.138873450513889	0.459461388926022	79.168398184286
a6039	loss_cnaOV84	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	3.13899583055004	2.29499954167898	0.843996288871061	1.69122993201245	1.54077909928154	0.53954660667762	0.499042899428087	0.547772415438796	0.504200233730461	NA	NA	0.226440043256568	0.408857497090685	79.168398184286
a6040	gain_cnaOV49	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.67401725069484	4.40606223903415	0.267955011660688	0.797587774978858	0.735214892749565	0.362328182184881	0.335956768730302	0.364458084708522	0.504316449316672	NA	NA	0.523747094643058	0.625254616805774	79.168398184286
a6041	loss_cnaOV34	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.69593181679136	3.17488472272798	0.521047094063378	1.12103127517309	1.01304758989983	0.508363339692931	0.464792647272867	0.514336245659395	0.504357410710051	NA	NA	0.564557028634566	0.513107350703188	79.168398184286
a6042	loss_cnaOV21, loss_cnaOV22	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.16520994431258	2.82386122293097	0.341348721381613	0.234684547889064	1.11238103774335	0.317129782984841	1.45450019804018	0.306863124954103	0.504446587915799	NA	NA	0.306113013893936	0.186095249465732	79.168398184286
a6043	gain_cnaOV94	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	1.65686075918592	2.23630805936371	-0.579447300177792	0.489951834415569	1.44232513062925	0.425986967481704	1.18266176280159	0.401745270794107	0.504461573362879	NA	NA	0.891925004751394	0.242427312279572	79.168398184286
a6044	loss_cnaOV43_(NF1)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.62037572747997	2.2310281664647	0.38934756101527	1.63084513853422	1.37773882475999	0.275090481614344	0.238739750216388	0.282598961441838	0.504478496945167	NA	NA	0.529300796173864	0.637287436166718	79.168398184286
a6045	loss_cnaOV43_(NF1)	152	CP466722	ATM	5	27	2.77258872223978	NA	2.90522230778058	2.59908231042668	0.306139997353905	0.729466557204509	0.824572513951546	0.376771386177274	0.419676535312471	0.371271164359833	0.504512469626084	NA	NA	0.555340606609017	0.430757783337097	79.168398184286
a6046	gain_cnaOV49	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	-0.0360014977033119	0.953735465695986	-0.989736963399298	0.757817800118136	2.13965185806172	0.477731328380333	1.30603551835944	0.462569160338021	0.504741853112102	NA	NA	0.41523850661148	0.145356109661142	79.168398184286
a6047	loss_cnaOV52, loss_cnaOV53	308	XL-880	MET	8	24	1.63315443905142	NA	-0.00313294817207841	0.338508850335264	-0.341641798507343	0.638655866534941	1.04688050138256	0.353240592577531	0.534938793189104	0.326342689596523	0.504780755390928	NA	NA	0.367601165964358	0.284713110715977	79.168398184286
a6048	loss_cnaOV35	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.40280294319063	2.81313280477318	-0.410329861582553	1.37898904527938	1.72931885576603	0.243256847255479	0.297558463562285	0.237278313489961	0.505115075479166	NA	NA	0.320619808230053	0.577695208241891	79.168398184286
a6049	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.69820062587604	2.03446502137027	0.663735604505769	1.00129545407289	1.60066556840873	0.430357488777145	0.662876877954395	0.414662261502638	0.505199219195824	NA	NA	0.947571689583945	0.395711291833111	79.168398184286
a6050	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.88213660446169	4.39802611428383	0.484110490177859	1.36591874733221	0.978133550777999	0.480427789844257	0.354421147761081	0.494932915646132	0.505234496068418	NA	NA	0.374273424118069	0.605016222758143	79.168398184286
a6051	gain_cnaOV4_(KRAS)	1239	YK 4-279	RNA helicase A	6	18	2.30258509299405	NA	1.34200189520595	1.64534490334261	-0.303343008136658	0.664047732668329	1.14900278924104	0.286583803350148	0.456809041298494	0.264005458452391	0.50525133087398	NA	NA	0.28604409995614	0.440579052311225	79.168398184286
a6052	gain_cnaOV26	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	2.41713085818471	1.52601968901544	0.891111169169267	1.93720186674312	2.37500066530742	0.382817116310002	0.459999127848988	0.375204597702259	0.505310974629005	NA	NA	0.612381133993485	0.528680327265793	79.168398184286
a6053	loss_cnaOV16, loss_cnaOV17	1009	ATRA	Retinoic acid and retinoid X receptor agonist	6	25	2.30258509299405	NA	4.68989849836372	4.46888870867506	0.22100978968866	1.37275903937777	0.801260376763793	0.2388445775974	0.160996783374916	0.275827678614654	0.505348773069106	NA	NA	0.527813108126015	0.717962230165119	79.168398184286
a6054	PIK3CA_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	1.86134890874182	1.86051498650679	0.000833922235030427	2.2219739745415	1.48552807116229	0.000494039231053029	0.000375306931847617	0.000561364171582403	0.505358222885418	NA	NA	0.344604809197954	0.99940649743956	79.168398184286
a6055	gain_cnaOV95_(MECOM)	193	GW-2580	CSF1R (cFMS)	9	23	2.99573227355399	NA	5.84615258902912	5.67964374223516	0.166508846793954	0.581762748806536	0.612510468212941	0.275465270774835	0.286214349639161	0.271846532320924	0.505461244812387	NA	NA	0.191728916727559	0.484058452042715	79.168398184286
a6056	NF1_mut	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.30224943731893	3.0355265138594	0.266722923459522	0.796537500312728	0.934230264848513	0.289348691041648	0.334852939572593	0.285500195717564	0.505463284627664	NA	NA	0.238237684113383	0.570715728023297	79.168398184286
a6057	gain_cnaOV95_(MECOM)	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-2.1690699387581	-2.68007793242067	0.511007993662575	2.34915307689241	1.89922767869085	0.25370839491663	0.217528605815064	0.269060944823012	0.505522971388748	NA	NA	0.343838981314831	0.676773377952612	79.168398184286
a6058	RB1_mut	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.94606256377585	4.55144146496611	0.39462109880974	0.760326145158637	0.956631613437621	0.417670515932565	0.519015558418558	0.41251103692014	0.505545363964828	NA	NA	0.943059884593311	0.471853654764799	79.168398184286
a6059	gain_cnaOV18_(CCNE1)	207	AS601245	JNK 	4	14	2.07944154167984	NA	2.22894402955399	1.9261924161304	0.302751613423592	0.523607184412808	1.07365667917672	0.304583711175006	0.57820370391424	0.281981772474739	0.505550720679791	NA	NA	0.478133615671783	0.45231577576932	79.168398184286
a6060	loss_cnaOV54	165	DMOG	Prolyl-4-Hydroxylase	6	13	8.29404964010203	NA	6.91808705529615	6.5958977864839	0.322189268812251	1.1598738365494	1.65629052113666	0.210977046308574	0.277779581416164	0.194524610689158	0.505741778829434	NA	NA	0.335715077341239	0.632979903780188	79.1769880619199
a6061	loss_cnaOV20	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.4126051233249	4.02317350755929	0.389431615765618	1.38424282208048	1.0736506536105	0.347691178255251	0.281331865734592	0.362717253005926	0.505772467678847	NA	NA	0.819380631299328	0.577031810769482	79.1769880619199
a6062	loss_cnaOV54	190	Bleomycin	DNA damage	6	13	4.15888308335967	NA	1.04050712311101	1.95574345077962	-0.915236327668616	0.891557104338587	2.68805760394827	0.396274979187441	1.0265594017644	0.340482408682128	0.506149117429659	NA	NA	0.612400968531722	0.286075039001024	79.2143977136992
a6063	gain_cnaOV49	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-3.75362799033123	-3.26821233550702	-0.485415654824209	2.42371944380973	1.78066289120847	0.264925596124301	0.200277163292962	0.272603903423166	0.506213808216156	NA	NA	0.138902972637951	0.764961002171984	79.2143977136992
a6064	loss_cnaOV21, loss_cnaOV22	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.65293817113532	2.32629364748321	0.326644523652113	1.03766779854798	0.855980037432496	0.375766703511321	0.31478718344078	0.38160296895694	0.506334945421396	NA	NA	0.650106603903767	0.644843347418393	79.2143977136992
a6065	loss_cnaOV16, loss_cnaOV17	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.0394964257381	6.82104401742833	-0.781547591690234	0.648406706624649	1.58510332946099	0.519140809817009	1.20533545335869	0.493057819742261	0.506345381588317	NA	NA	0.335734061314508	0.190982083139124	79.2143977136992
a6066	loss_cnaOV57_(ZNRF3)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	3.45417517216149	4.11533486013477	-0.661159687973273	1.47573381136097	1.49487357262198	0.442848419827514	0.448020966168369	0.442284685529366	0.50650852781594	NA	NA	0.329074902818715	0.450513227937869	79.2259793795583
a6067	loss_cnaOV102	346	THZ-2-102-1	CDK7	3	29	0.916290731874155	2.99573227355399	-0.433486214452122	-1.12416980540487	0.690683590952751	0.825483589731727	2.03619542881584	0.3490655077503	0.836701782499657	0.339202996519062	0.506586409945925	NA	NA	0.442957908673679	0.306177110498046	79.2259793795583
a6068	gain_cnaOV72_(ASXL1)	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.271916245643002	-0.168083454506246	0.439999700149248	0.743788538592327	1.30777881146988	0.34887783126132	0.591565582580741	0.336448102913297	0.50706377523197	NA	NA	0.76681226628159	0.363689353229316	79.2513211180154
a6069	gain_cnaOV96	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-1.79714411378207	-2.74519095283677	0.948046839054705	2.24516974200309	1.92664282476727	0.477228463156881	0.422260651975863	0.492071922656045	0.507064531154096	NA	NA	0.343887398796905	0.480670030488249	79.2513211180154
a6070	gain_cnaOV18_(CCNE1)	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	1.74319294206974	2.25303081426675	-0.509837872197004	1.3928547216523	1.35348297325045	0.374618572131633	0.366038082989877	0.376685841102682	0.50709414442808	NA	NA	0.891945268862522	0.545962709080253	79.2513211180154
a6071	gain_cnaOV51_(MYC)	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	0.972631311766975	1.56751994548657	-0.594888633719592	1.15261536574678	1.91834409786008	0.332889957824996	0.516120686395816	0.310105280060648	0.50714506820768	NA	NA	0.614137020230121	0.324273165000083	79.2513211180154
a6072	ARID1A_mut	288	KIN001-055	JAK3, MNK1	8	24	2.32630161961136	NA	3.56138527838268	3.88085524153007	-0.319469963147396	0.67773692483414	1.11512406107184	0.310219455703385	0.471377538158451	0.286488270049815	0.507166076853724	NA	NA	0.716820192619217	0.345101617375987	79.2513211180154
a6073	gain_cnaOV4_(KRAS)	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.7719384386896	1.57038425203178	0.201554186657813	0.38745315455049	0.739726969150399	0.294693554148342	0.520202724614927	0.272471053596038	0.507364162751538	NA	NA	0.208454664434865	0.34482333735233	79.2548792999257
a6074	gain_cnaOV18_(CCNE1)	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.59845890747635	4.23215186756049	0.366307039915855	1.14993752018419	0.861483526913733	0.409499162063379	0.318545167442821	0.425204926701444	0.50742297923374	NA	NA	0.520984014275936	0.5774700595389	79.2548792999257
a6075	loss_cnaOV83	1026	17-AAG	HSP90	5	28	0	NA	-0.814310098482543	-0.480211097541389	-0.334099000941154	2.15925557401747	2.33410239024124	0.144488705036853	0.154728789385286	0.14313810839576	0.507499166658955	NA	NA	0.0609624572101347	0.763986932604263	79.2548792999257
a6076	loss_cnaOV83	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.58885735384944	4.32548920276052	0.263368151088921	0.996567538441764	1.07701159944584	0.246914666804807	0.264275265779502	0.244536039560235	0.507547317651797	NA	NA	0.351173370256649	0.611745559551174	79.2548792999257
a6077	PIK3CA_mut	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	2.34643813676484	2.46575193301787	-0.119313796253027	0.992789923104431	1.56603365193696	0.0811997588343717	0.120180305496993	0.0761885264122215	0.507677774282307	NA	NA	0.239499668456406	0.810369694331917	79.2548792999257
a6078	loss_cnaOV40	303	PIK-93	PI4K, PI3K	7	25	2.99573227355399	NA	2.5321262615598	3.00981799846453	-0.47769173690473	0.547897060150776	1.36058078950702	0.384812262572222	0.871864026379834	0.351093989117554	0.507690022065584	NA	NA	0.23098327322315	0.174440117264289	79.2548792999257
a6079	SMARCA4_mut	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.47283536541278	-4.12265909694931	0.649823731536529	0.599371795070358	1.57161602416035	0.426225338271826	1.08417469237145	0.413474870163469	0.507787147904246	NA	NA	0.863897114790063	0.20569534443188	79.2570015173856
a6080	MLL2_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.71156550591937	2.10839529453386	0.603170211385519	0.880940475404044	1.3258817502457	0.463943493523541	0.684688952575229	0.454920064533466	0.507926176907462	NA	NA	0.686116603420168	0.363716752073901	79.2612775258402
a6081	loss_cnaOV52, loss_cnaOV53	1268	XAV 939	TNKS1 (tankyrase-1)	8	24	1.6094379124341	NA	2.98396986974077	2.81316026416707	0.170809605573699	0.981023256305722	1.10654184545075	0.158367977712156	0.174113716953993	0.154363439824655	0.508033041339475	NA	NA	0.30617510016413	0.686341956175696	79.2612775258402
a6082	gain_cnaOV4_(KRAS)	256	JW-7-24-1	LCK	8	24	2.32630161961136	NA	2.21931187883068	1.84602164869943	0.373290230131249	1.6059822098891	1.25156852335878	0.278023101804878	0.232437338242387	0.298257924487798	0.508124065371125	NA	NA	0.838836890851286	0.562154464115697	79.2612775258402
a6083	loss_cnaOV41	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-2.19731608216866	-2.8312323889531	0.633916306784438	1.81701176334379	1.75961723883307	0.358676227549528	0.34887848255746	0.36025806794484	0.508148687091485	NA	NA	0.695883704223205	0.500988028871645	79.2612775258402
a6084	loss_cnaOV20	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	1.31495851906138	1.60587352734374	-0.29091500828236	0.0901725515365009	1.11409109496487	0.273778639022808	3.22620357664606	0.261123178882903	0.508234433065001	NA	NA	0.286114828194303	0.254816454755205	79.2616222024508
a6085	KRAS_mut	1066	AZD6482	PI3Kbeta	7	26	1.6094379124341	NA	2.5227909233273	2.34043130200663	0.182359621320672	1.34858704902415	1.30731713378715	0.138633724543213	0.135222729190993	0.139491494915543	0.508516515008958	NA	NA	0.109601023094603	0.756342954874555	79.2925812796291
a6086	gain_cnaOV72_(ASXL1)	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.64156022979329	4.35391612442926	0.287644105364033	0.722402892975895	0.879686571376613	0.334078361063845	0.398176845858273	0.326984763350317	0.508791930887743	NA	NA	0.86935677620434	0.457166096107436	79.3224909194186
a6087	PIK3R1_mut	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	2.67935135608828	1.47685334565852	1.20249801042976	2.21848513739735	2.31839901963993	0.521268428245424	0.5420356396169	0.518676034730432	0.509124001070524	NA	NA	0.612470909114176	0.457475011974501	79.3276143504878
a6088	BRCA1_mut	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.29331231299714	2.98360630043218	0.309706012564958	0.380565662219412	1.25842995377894	0.258555337397216	0.813804405680719	0.246105086449144	0.509339846699039	NA	NA	0.0881513849571038	0.329776651276992	79.3276143504878
a6089	loss_cnaOV54	1003	Camptothecin	TOP1	10	21	-2.30258509299405	NA	-3.24545314416052	-3.90341303060431	0.657959886443792	1.12445789677787	1.92159555005862	0.383796988111349	0.585135191214514	0.342402898686834	0.509448904517355	NA	NA	0.244565370501432	0.24162437806424	79.3276143504878
a6090	loss_cnaOV38	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-3.19921566544742	-2.62674497365963	-0.572470691787794	1.65303177694022	1.1036511384957	0.469726915058034	0.346315600083288	0.518706203273695	0.509450494910791	NA	NA	0.377746307533383	0.550625834214512	79.3276143504878
a6091	loss_cnaOV39	1175	AG-014699	PARP1, PARP2	10	23	1.6094379124341	NA	4.16380714333975	3.78696262337017	0.376844519969581	1.28792559625439	0.964601184192201	0.352654018702604	0.292598051522183	0.390673913888222	0.509472445218937	NA	NA	0.315821662717348	0.421081220887574	79.3276143504878
a6092	gain_cnaOV18_(CCNE1)	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.65893579974241	4.42236241539501	0.2365733843474	0.260772333751999	0.578736955818851	0.426107564565518	0.907202773176036	0.408775320063454	0.509472869625231	NA	NA	0.364244672558513	0.200841244074179	79.3276143504878
a6093	gain_cnaOV72_(ASXL1)	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.38099948927181	2.86438999314035	-0.483390503868538	0.96286852371034	1.26112408157144	0.394424944349525	0.502031681340907	0.383301303124911	0.509577229377099	NA	NA	0.0943781586767886	0.361421717149215	79.3276143504878
a6094	loss_cnaOV40	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.66943060586198	2.18087104073493	0.488559565127049	2.07184871720663	1.18865909888532	0.349609900037106	0.235808512981464	0.411017393956942	0.509593420917592	NA	NA	0.746267258158702	0.677985718334486	79.3276143504878
a6095	gain_cnaOV51_(MYC)	1149	TW 37	BCL2, BCL2L1	8	25	1.6094379124341	NA	-0.778023326683243	-0.728350529132404	-0.0496727975508389	0.720308767379298	0.983837932672145	0.0533613781529707	0.0689604233633912	0.0504888009511134	0.50959651843622	NA	NA	0.0417032727268663	0.879246834162402	79.3276143504878
a6096	gain_cnaOV18_(CCNE1)	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.33720805098259	3.87514140349616	0.462066647486435	1.67129178713842	1.18370657556937	0.37763286351569	0.27647275660798	0.390355732597142	0.50966985743739	NA	NA	0.698374541012004	0.682677133619017	79.3276143504878
a6097	loss_cnaOV1	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.34720039468924	5.03250156930966	0.314698825379581	0.42208086914608	0.626945801633559	0.511361582232672	0.745588934215983	0.501955391613769	0.509759498096302	NA	NA	0.110139176942539	0.327995504988344	79.3276143504878
a6098	gain_cnaOV51_(MYC)	1054	PD-0332991	CDK4, CDK6	8	25	1.38629436111989	0.693147180559945	2.84348388538951	2.10517212395714	0.738311761432372	2.15419751578565	1.64865289839461	0.415848229071624	0.342731692902869	0.447827291087959	0.50982806309605	NA	NA	0.110124852848407	0.395057091674354	79.3276143504878
a6099	loss_cnaOV35	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	4.52924379981102	3.78207342636134	0.747170373449679	2.42342740194314	1.56093910305849	0.437959398957792	0.30831143233364	0.478667215130737	0.509915052009097	NA	NA	0.146767505800288	0.538449634323122	79.3281406684235
a6100	PIK3CA_mut	1003	Camptothecin	TOP1	7	24	-2.30258509299405	NA	-3.79577933205971	-3.66065623999491	-0.135123092064799	1.59428248476901	1.77927068317644	0.0775406751034418	0.0847547993255262	0.075942965475928	0.510009700514627	NA	NA	0.24457500854044	0.851270557588799	79.3298582311066
a6101	NF1_mut	309	Y-39983	ROCK	4	28	2.99573227355399	NA	5.27237779415031	4.920276996499	0.352100797651309	1.36518320128092	1.22720141793397	0.28356583408545	0.257914686703543	0.286913617036135	0.510199778431437	NA	NA	0.371995712064517	0.652591467171193	79.3464164402654
a6102	TP53_mut	190	Bleomycin	DNA damage	12	7	4.15888308335967	NA	1.92515940802344	1.22368495750283	0.701474450520608	2.57472728112063	1.7806432072614	0.301627489196271	0.272446117172961	0.393944417197123	0.510592404696941	NA	NA	0.612505169096561	0.494034724805044	79.3732524428319
a6103	loss_cnaOV87, loss_cnaOV88	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.66480328677986	4.26045431387127	0.404348972908592	1.2923782943872	0.749175147585647	0.506329147280376	0.312871993180851	0.539725555781821	0.510754031197068	NA	NA	0.224521085410735	0.644449430424063	79.3732524428319
a6104	loss_cnaOV21, loss_cnaOV22	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	3.92906409388504	4.32186195436558	-0.392797860480548	0.322335044122431	0.84241201940954	0.480639410267823	1.2186011655976	0.466277606955165	0.510833858762126	NA	NA	0.316257739900119	0.161829322438869	79.3732524428319
a6105	loss_cnaOV38	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	8	25	1.6094379124341	NA	2.78664768559836	2.20223211740898	0.584415568189381	1.82746295415109	1.45127923036357	0.378445013154917	0.319796123287685	0.402689955152859	0.510863327453738	NA	NA	0.241606614410941	0.428581188856317	79.3732524428319
a6106	gain_cnaOV19	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	5.48250426053533	4.62533584520088	0.857168415334449	1.61621340671455	1.54847193639432	0.550669035913255	0.530355961516808	0.553557604234275	0.510868351360425	NA	NA	0.120796015857745	0.463911293452751	79.3732524428319
a6107	SMARCA4_mut	292	Masitinib	KIT	3	29	2.99573227355399	NA	3.45715364100442	4.07107560445199	-0.613921963447571	0.386498436992155	1.07418578652998	0.588866178978015	1.58842030054582	0.571523074635689	0.511084114928319	NA	NA	0.104281648165168	0.0846529057187014	79.3732524428319
a6108	SMAD4_mut	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.943547029963572	0.60842989221126	0.335117137752312	1.08546200063172	0.565595576201942	0.545703417570235	0.308732261062368	0.592503109735533	0.511352480029027	NA	NA	0.0149867429532882	0.648077316055316	79.3732524428319
a6109	gain_cnaOV19	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.69123397464259	1.11553787302361	0.575696101618984	0.429798767067444	1.54175692576144	0.385033501567584	1.33945498621834	0.373402636952423	0.511445925523465	NA	NA	0.812861032074071	0.157971055953776	79.3732524428319
a6110	KRAS_mut	229	LY317615	PRKCB (PKCbeta)	7	25	2.99573227355399	2.32630161961136	2.24243957338309	2.89086093724589	-0.648421363862801	1.78592432785752	1.64106674285631	0.38803388573036	0.363073257779448	0.395121872212344	0.511511069762175	NA	NA	0.320729928410906	0.409967620609179	79.3732524428319
a6111	gain_cnaOV51_(MYC)	329	QL-XI-92	DDR1	8	24	2.32630161961136	NA	4.82320084969713	4.43716561855463	0.386035231142493	1.17632098480157	0.954917857967111	0.381863352598166	0.328171677739483	0.404260144390125	0.511592010359033	NA	NA	0.190829008984399	0.419791930773936	79.3732524428319
a6112	PIK3CA_mut	1038	NU-7441	PRKDC (DNAPK)	7	26	0.693147180559945	NA	2.16968405125498	2.63594935929358	-0.466265308038599	0.791035243843591	1.07357829102026	0.454897842502206	0.58943683188254	0.434309553330752	0.511673019560583	NA	NA	0.394586041879807	0.225155874869616	79.3732524428319
a6113	KRAS_mut	1175	AG-014699	PARP1, PARP2	7	26	1.6094379124341	NA	3.59475025364341	3.98365230751568	-0.388902053872267	1.01448827072583	1.08405374909977	0.363140102062586	0.383348004205137	0.358747944181939	0.511734086431733	NA	NA	0.315859001120546	0.395840728734288	79.3732524428319
a6114	loss_cnaOV54	272	AR-42	HDAC	9	21	1.63315443905142	NA	-0.132787354984959	0.478477116313966	-0.611264471298925	1.31815347856801	2.00721871100709	0.332767618977479	0.463727844471479	0.304533067546103	0.511772083965131	NA	NA	0.485496417070809	0.334841994618977	79.3732524428319
a6115	loss_cnaOV39	1199	Tamoxifen	ER	9	23	1.6094379124341	NA	4.15665014697826	3.91066080608709	0.245989340891167	1.04396494146686	0.624348737109811	0.323981153163893	0.235629886713945	0.393993494773262	0.511802115020665	NA	NA	0.52508242898193	0.522428877204987	79.3732524428319
a6116	gain_cnaOV4_(KRAS)	194	AUY922	HSP90	6	13	-1.36257783450257	NA	-2.18531915837061	-2.71188659980433	0.52656744143372	2.22570281795958	1.91530993402864	0.261768100159327	0.236584793434575	0.274925447875762	0.511802684007743	NA	NA	0.344034639965871	0.629444680914239	79.3732524428319
a6117	loss_cnaOV35	305	TPCA-1	IKK	5	27	2.99573227355399	NA	2.98736002273533	3.38775704637796	-0.40039702364263	1.14909904751414	1.2437698715214	0.325111680207136	0.348444309051351	0.321922111807434	0.51181864942425	NA	NA	0.993603854866017	0.507009868558291	79.3732524428319
a6118	loss_cnaOV44	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.4712343323022	2.90437419046707	-0.433139858164868	0.736016043474221	0.803699700040614	0.541854397750028	0.588492413997276	0.538932462140997	0.511873844254055	NA	NA	0.0193536869159763	0.419114766695036	79.3732524428319
a6119	loss_cnaOV55	1059	AZD8055	MTORC1/2	8	25	0.693147180559945	NA	0.625584473584219	0.170896746562648	0.454687727021571	0.908779595225554	1.18717991626995	0.402262837728935	0.50032783461508	0.382998162949194	0.512009952500294	NA	NA	0.146357613828784	0.272480745201327	79.3732524428319
a6120	gain_cnaOV4_(KRAS)	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.78567802518909	2.48521825755519	0.300459767633902	1.04174048333695	1.04243485720239	0.28824938472402	0.288420938266174	0.288228818863803	0.512060582916264	NA	NA	0.195124127408498	0.619876247723699	79.3732524428319
a6121	loss_cnaOV59	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.65325451552687	3.25232500320885	0.400929512318016	0.494506941842931	1.15591333016573	0.361951208892428	0.810766196372957	0.346850842407477	0.512119313418539	NA	NA	0.950867402181087	0.255515189753281	79.3732524428319
a6122	loss_cnaOV70	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.666434511396998	1.27102185861127	-0.604587347214272	1.0986772794462	1.24473869374501	0.489213083578712	0.550286565968688	0.485714270997128	0.512129066237009	NA	NA	0.266408248960724	0.44628500411558	79.3732524428319
a6123	gain_cnaOV95_(MECOM)	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.28095058011132	-1.67631419825539	0.395363618144068	1.30623624244249	1.32058240074155	0.300149823649051	0.302673900247011	0.29938579972144	0.51239763196964	NA	NA	0.621205330032866	0.58016167130771	79.4019066609235
a6124	loss_cnaOV83	1001	AICAR	AAPK1 (AMPK) agonist	5	26	7.60090245954208	NA	8.47929616073211	8.80155986960273	-0.322263708870622	1.0641504354094	1.26539317131261	0.259978253339638	0.302836608572773	0.254674765263933	0.512605573109697	NA	NA	0.529425122064912	0.568872887486907	79.4210352295602
a6125	gain_cnaOV19	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-4.08663660378707	-4.76049593390925	0.67385933012218	1.96112180537616	2.08572761266133	0.325306907570156	0.343609116106344	0.32308117609967	0.512688481233065	NA	NA	0.348704355263266	0.627291457132846	79.4210352295602
a6126	loss_cnaOV59	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.30927546620715	-0.173618153849083	0.482893620056232	0.869108352357723	1.2967877887978	0.383462303704365	0.555619582697871	0.372376748322025	0.512950005183327	NA	NA	0.766861891993299	0.3775702981407	79.4260720326675
a6127	loss_cnaOV38	157	JNK-9L	JNK	4	15	1.63315443905142	NA	-0.425117378286492	0.0734652107129776	-0.49858258899947	1.57757752341819	0.822116572152574	0.499634224579024	0.316043162125672	0.606462156204947	0.512990560270796	NA	NA	0.189584519197614	0.579540726506162	79.4260720326675
a6128	loss_cnaOV84	230	GSK429286A	ROCK2	6	26	2.99573227355399	2.32630161961136	5.84209328117018	5.46874253360266	0.373350747567516	0.961639328525151	0.980070753844708	0.382130972363353	0.388244050022493	0.380942647357757	0.513102536064445	NA	NA	0.303635899413404	0.419151141725147	79.4260720326675
a6129	gain_cnaOV95_(MECOM)	269	NSC-207895	MDM4	8	23	2.99573227355399	NA	3.56024906256133	3.99791561242608	-0.43766654986475	1.9938584375353	1.44064923022221	0.274936395820587	0.219507333933782	0.303798135370706	0.513106174519081	NA	NA	0.715273534024642	0.580916889941398	79.4260720326675
a6130	loss_cnaOV84	228	KIN001-102	AKT1	6	26	2.32630161961136	NA	2.64104401374132	2.82297166071925	-0.181927646977935	1.20495745369551	1.24297324877289	0.147105146627777	0.150982631311983	0.146364893337439	0.513162130861146	NA	NA	0.0944184655447389	0.749238720063413	79.4260720326675
a6131	loss_cnaOV36	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	0.715094328013438	1.5101291032145	-0.795034775201066	0.389785692637528	1.8510599202441	0.444396572411816	2.03967151749818	0.429502452355094	0.513294502746383	NA	NA	0.614217832852488	0.0737106295603655	79.4260720326675
a6132	loss_cnaOV52, loss_cnaOV53	157	JNK-9L	JNK	5	14	1.63315443905142	NA	-0.384476915378943	0.094563801745958	-0.479040717124901	0.778841855195778	1.05399184534978	0.480910524347816	0.615068019173783	0.454501350497571	0.513306962278833	NA	NA	0.189593198396946	0.310862651410095	79.4260720326675
a6133	gain_cnaOV72_(ASXL1)	1502	Bicalutamide	ANDR (androgen receptor)	5	27	2.30258509299405	NA	4.67439178040921	4.48686649156456	0.187525288844646	0.512476997249318	0.612346778498537	0.312546290839072	0.365919426337521	0.306240345224734	0.513423971986319	NA	NA	0.614648201572098	0.492861179187127	79.4312238611493
a6134	gain_cnaOV26	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.93262784427434	3.35584367648766	0.576784167786678	0.951415747276461	1.23603528266428	0.47311142169944	0.606237777162918	0.466640536784205	0.51359134461415	NA	NA	0.326205871563145	0.409827084751862	79.4338817611535
a6135	loss_cnaOV1	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.66809734346995	4.40667464322983	0.261422700240115	1.17463150820182	0.698399242065018	0.353393970570149	0.222557200632489	0.374316987325393	0.513608587563182	NA	NA	0.523885420009614	0.739135921625847	79.4338817611535
a6136	loss_cnaOV16, loss_cnaOV17	1007	Docetaxel	Microtubules	6	25	-4.38202663467388	NA	-4.15074781608947	-4.76805350612999	0.617305690040513	1.80566561987567	1.31357139637579	0.437583446319134	0.341871542131382	0.469944528134284	0.51377173857714	NA	NA	0.134994980866272	0.458740350274963	79.4389585349109
a6137	loss_cnaOV84	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	6	26	2.99573227355399	NA	3.56277448904304	4.14113191685235	-0.578357427809311	1.11139383243947	1.55681914941559	0.387679061488194	0.520389272396659	0.37149943076331	0.513992364232727	NA	NA	0.329202916437234	0.314811561536553	79.4389585349109
a6138	loss_cnaOV38	1020	Lenalidomide	TNFA	8	23	1.6094379124341	NA	4.66396781178566	4.30808384389924	0.35588396788642	0.878626492178673	0.72035623785962	0.467298821221663	0.405045797109939	0.494038850755081	0.514106688741911	NA	NA	0.042859367813718	0.325582976456138	79.4389585349109
a6139	PTEN_mut	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	4.15781709752169	3.1573345162448	1.00048258127688	0.799111535589494	1.06955404965348	0.949507086721234	1.25199366636454	0.935420310550012	0.514160013127958	NA	NA	0.0621033039384318	0.146843351322478	79.4389585349109
a6140	loss_cnaOV82	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.66249633328775	4.26070148745971	0.401794845828034	0.978642323171481	0.783739676513358	0.50305497628546	0.410563528997948	0.512663653338962	0.51417859973147	NA	NA	0.22457825052367	0.554770121953413	79.4389585349109
a6141	loss_cnaOV59	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.775870571089	4.44706255260894	0.328808018480056	0.558340456620302	0.684640778650304	0.488806060338346	0.588902370554282	0.480263561174761	0.514235866279584	NA	NA	0.0531575783510281	0.341049875035309	79.4389585349109
a6142	loss_cnaOV33_(ZFHX3)	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	2.14770936087905	1.16734765455379	0.980361706325257	2.29079187418436	2.32593842765354	0.422124340290146	0.427957562349183	0.421490824808405	0.51437628512306	NA	NA	0.362948640707303	0.469643254895007	79.4389585349109
a6143	loss_cnaOV85	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.21883394233313	3.56858746533701	-0.349753523003884	0.763870962831385	1.18752071469414	0.314194031695475	0.457869902146141	0.294524144864258	0.514494058570322	NA	NA	0.726496526396211	0.367803910935478	79.4389585349109
a6144	loss_cnaOV43_(NF1)	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	3.55565715099162	3.98989606522623	-0.434238914234614	0.935420143419686	1.26024639522524	0.355760625960091	0.464218049279048	0.344566678293893	0.514506160085947	NA	NA	0.698425770684958	0.400598991345631	79.4389585349109
a6145	loss_cnaOV55	333	T0901317	LXR	7	25	2.32630161961136	NA	5.16975956908512	4.63675756245996	0.533002006625162	0.416906781021892	1.2184387164965	0.482076183250251	1.27846806741475	0.437446708979961	0.514557811963814	NA	NA	0.00506892745465347	0.0767413832942196	79.4389585349109
a6146	gain_cnaOV94	261	TL-1-85	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.32216978049315	3.62095876809639	-0.298788987603245	0.635547842492764	1.02442534064364	0.311451163570716	0.470128238389302	0.291664971324818	0.514589955731375	NA	NA	0.728182233968259	0.358200653337515	79.4389585349109
a6147	SMAD4_mut	326	GSK690693	AKT	3	29	2.32630161961136	NA	4.82455543413632	4.08234932608898	0.742206108047338	1.1982617550459	1.46940012366121	0.510844840589999	0.619402317500244	0.505108238454498	0.514646090867174	NA	NA	0.093215880385414	0.400051762077429	79.4389585349109
a6148	loss_cnaOV81_(RB1)	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	3.83639436686121	3.30920202934539	0.527192337515813	1.35234140351645	1.70481092084706	0.315135070010078	0.389836720331841	0.309238010543639	0.514832550113543	NA	NA	0.629390853074848	0.516315604058641	79.4458420633218
a6149	KRAS_mut	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.44977774393641	1.90220911414882	0.547568629787585	0.831964683551866	0.998547052064475	0.559157069552586	0.658163309829304	0.548365376128745	0.514981109711281	NA	NA	0.478421717588188	0.38341991800988	79.4458420633218
a6150	loss_cnaOV55	1069	EHT 1864	Rac GTPases	8	25	2.30258509299405	NA	4.51164330867996	4.13898243270807	0.372660875971898	0.56950606357258	1.06153765729413	0.383221006075076	0.654358047804007	0.351057612898835	0.515234620286604	NA	NA	0.209118961720056	0.215554561143258	79.4458420633218
a6151	KRAS_mut	211	TL-2-105	CRAF	7	25	2.32630161961136	1.63315443905142	4.21439435680226	4.46368173040297	-0.249287373600714	0.557581896101292	0.644725392512413	0.396787349807066	0.44708656314664	0.386656670414783	0.515236679922682	NA	NA	0.270631316907142	0.334753018694772	79.4458420633218
a6152	gain_cnaOV26	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	-0.34077988695051	0.204863475006387	-0.545643361956897	1.20767290074781	1.34770661848901	0.409643273153639	0.451813865839852	0.404868058427025	0.5154062490956	NA	NA	0.869612889561539	0.531501068171587	79.4458420633218
a6153	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.52363116066649	4.84157220968463	-0.31794104901814	0.339420851672583	0.768201287621363	0.425447640449731	0.936716313836949	0.413877266468276	0.515422137549557	NA	NA	0.764963921569192	0.251397517989697	79.4458420633218
a6154	loss_cnaOV58	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	1.90807666103013	1.46732320339127	0.440753457638858	1.85191417126226	0.775565164146585	0.412770099937625	0.237998857872793	0.568299709701187	0.515431034379769	NA	NA	0.453393395876552	0.628368427860291	79.4458420633218
a6155	loss_cnaOV16, loss_cnaOV17	271	VNLG/124	HDAC, RAR 	6	25	1.63315443905142	NA	4.5149977329801	4.28480039863605	0.230197334344052	0.54206947411393	0.593391286390575	0.393591163467023	0.424663895195968	0.387935144353525	0.515666147155395	NA	NA	0.253511859741868	0.385621191031154	79.4458420633218
a6156	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	152	CP466722	ATM	5	27	2.77258872223978	NA	2.89937352075411	2.60016541913529	0.299208101618821	0.808558877689931	0.813563726357611	0.368075736900012	0.37005109940004	0.367774633904094	0.515715470821869	NA	NA	0.555499007653059	0.478331242398225	79.4458420633218
a6157	gain_cnaOV50	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	0.817843304557815	1.52435276503019	-0.706509460472376	0.856877281104775	1.86659197930163	0.394969901218131	0.824516504348756	0.378502355258544	0.515734219315075	NA	NA	0.614249426955448	0.240973598965016	79.4458420633218
a6158	SMARCA4_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	0.222632029947496	1.40029916141999	-1.1776671314725	2.39608649232718	2.31396140987719	0.507718682589592	0.491496085489259	0.508939832118894	0.515806285603026	NA	NA	0.36297256712746	0.488926242104653	79.4458420633218
a6159	loss_cnaOV33_(ZFHX3)	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.336272482493156	-0.796133100407015	0.459860617913859	1.38495617775308	0.85313896351362	0.50084588567871	0.332039832956972	0.539021938489295	0.515820533805497	NA	NA	0.0417441627981498	0.559384685620463	79.4458420633218
a6160	loss_cnaOV84	1025	SB 216763	GSK3A, GSK3B	5	18	2.30258509299405	NA	5.22529679724457	4.8862503212257	0.339046476018865	1.26932902019674	0.675013548496873	0.412445583644816	0.267106849858609	0.502280993876133	0.515837416422964	NA	NA	0.45337825593816	0.591937340977998	79.4458420633218
a6161	PIK3R1_mut	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	2.98253378487797	2.90581302950657	0.0767207553713996	0.357876283906147	0.941969227573288	0.0890243649996285	0.214377869731987	0.0814471992562309	0.515862911286268	NA	NA	0.329176900774996	0.782384930494711	79.4458420633218
a6162	gain_cnaOV51_(MYC)	298	OSI-930	KIT, VEGFR, PDGFR	8	24	2.32630161961136	NA	4.40994722174905	4.46543908992152	-0.0554918681724752	0.688979950994161	1.06731327419848	0.0559379062752996	0.0805420652551696	0.0519921090779535	0.516229235255215	NA	NA	0.0311351122980915	0.866963200213261	79.4893560302809
a6163	KRAS_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	0.693147180559945	2.48078131370018	2.91099643026812	-0.430215116567941	1.57448700690185	1.55950084050995	0.275353075504416	0.273241452410893	0.275867191214377	0.516448548538538	NA	NA	0.968780222554331	0.53555475737055	79.505624178575
a6164	loss_cnaOV39	1262	UNC1215	LMBL3	10	23	0	NA	2.91924396621961	2.72005128641775	0.199192679801855	0.667477846529478	0.394661577247485	0.406698466103173	0.29842590407689	0.504717690511192	0.516502472585189	NA	NA	0.109366480394782	0.396773816855732	79.505624178575
a6165	gain_cnaOV50	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	1.04596942815946	1.4628109728078	-0.416841544648342	0.840943129354837	1.52846657379296	0.283121194922114	0.495683394153108	0.272718783515122	0.516622638241741	NA	NA	0.475975739041021	0.445435767400003	79.5112220810572
a6166	loss_cnaOV39	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	2.69661910291339	2.35572972231765	0.340889380595741	1.27956986013491	0.659301786880992	0.402399694118383	0.266409354593425	0.517046043828293	0.516713400153616	NA	NA	0.621195600738307	0.594831335104907	79.5122934947952
a6167	loss_cnaOV70	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.940820507000142	0.608711946310925	0.332108560689217	0.338993800177053	0.629320310732637	0.540673869395416	0.979689187577354	0.527725794043712	0.51700860466268	NA	NA	0.015005003975353	0.225459899357038	79.5208877251288
a6168	gain_cnaOV4_(KRAS)	1047	Nutlin-3a	MDM2	7	26	2.07944154167984	1.38629436111989	4.09506967426362	3.65417804918332	0.440891625080291	1.68160082301532	1.53204946112574	0.28224060325226	0.262185662046548	0.287778975984449	0.517025789422284	NA	NA	0.164774488779863	0.546363843036996	79.5208877251288
a6169	PIK3R1_mut	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	3.72250250931722	4.02750138208227	-0.304998872765053	0.282485863322057	0.808001846336514	0.401711686581178	1.07969605692207	0.377472989879813	0.517041553237187	NA	NA	0.525158853134287	0.144657497070366	79.5208877251288
a6170	loss_cnaOV70	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	0.509345421732606	0.877323657954727	-0.367978236222121	1.56846779670874	1.3359158751464	0.272147740657057	0.234610004103549	0.275450156007612	0.517104487975504	NA	NA	0.16290999715366	0.728212480376102	79.5208877251288
a6171	gain_cnaOV48_(SOX17)	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.82323550178711	2.34938647294652	-0.526150971159411	1.17375070458566	1.26304278148892	0.418547329900437	0.44826466906799	0.416574148453756	0.51751995574792	NA	NA	0.844357390959936	0.525996754470142	79.5548705979777
a6172	loss_cnaOV41	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-1.82592698466224	-2.176727432579	0.350800447916764	0.623054495505419	1.36926116140047	0.270403354611817	0.563033330868107	0.256196887639731	0.517594471769084	NA	NA	0.607199296234165	0.373722950048155	79.5548705979777
a6173	gain_cnaOV4_(KRAS)	312	AV-951	VEGFR	8	24	-2.05572501506252	NA	0.753602278707742	0.601928738931472	0.15167353977627	0.511158785738891	0.647803053024614	0.24517849798048	0.296724900379092	0.234135265445418	0.517623210801426	NA	NA	0.0150069682685532	0.508397668932684	79.5548705979777
a6174	loss_cnaOV40	1527	GDC0941 (rescreen)	PI3K	6	25	1.38629436111989	NA	0.591601772723939	0.332044334731227	0.259557437992712	0.59352158180559	0.966125344061236	0.28435311378071	0.437317607226845	0.268658140052127	0.517660851296995	NA	NA	0.909560379408746	0.41822879106673	79.5548705979777
a6175	loss_cnaOV41	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.81602298280794	3.33471241618243	0.481310566625512	1.29129969281767	1.20648333639261	0.395121379213358	0.372733432295078	0.398936771115822	0.517768016860127	NA	NA	0.326276015040543	0.47196561296737	79.5584539102283
a6176	loss_cnaOV43_(NF1)	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	9.20558712890914	8.671339655917	0.534247472992138	1.01756918363513	1.79780295922366	0.312158146784684	0.525023243219309	0.297166867064698	0.517976257537911	NA	NA	0.921713822167315	0.37593681121208	79.5737194406837
a6177	PIK3CA_mut	222	BX-912	PDPK1 (PDK1)	6	26	2.32630161961136	NA	2.91832078046933	3.52336251800574	-0.605041737536411	0.688458168921472	1.2858972954142	0.501261849391785	0.878835875365181	0.470521043705532	0.518172619222774	NA	NA	0.32628275739359	0.130766247636851	79.5737194406837
a6178	gain_cnaOV4_(KRAS)	1017	Olaparib	PARP1, PARP2	5	26	1.6094379124341	NA	4.23286345403842	3.91901604411356	0.313847409924857	0.935321303045558	1.20468082462638	0.267967011002496	0.335550370661845	0.260523288417241	0.5182597159233	NA	NA	0.0825606619403442	0.534870388363191	79.5737194406837
a6179	KRAS_mut	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	3.4371461037785	3.74985743206851	-0.31271132829001	1.14447245036104	1.02916127704803	0.296905852496434	0.273236221799277	0.303850655153842	0.518382728959605	NA	NA	0.830821316011637	0.530376674134282	79.5737194406837
a6180	gain_cnaOV72_(ASXL1)	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	4.92173537256556	4.71772965430386	0.204005718261697	2.08322165275045	1.46131270178755	0.128398392915932	0.09792799436025	0.139604424167494	0.518408370809811	NA	NA	0.120965107224128	0.863246164269496	79.5737194406837
a6181	loss_cnaOV85	1026	17-AAG	HSP90	7	26	0	NA	-0.686440884936249	-0.488937501116072	-0.197503383820177	2.08312339678082	2.36616527648006	0.0853483189275549	0.0948111783130041	0.0834698175074171	0.518700328686452	NA	NA	0.0610564016501004	0.833013095217562	79.5737194406837
a6182	gain_cnaOV19	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.76562742193345	1.29428386208924	0.471343559844212	0.251937604840007	1.40345786481619	0.347646292132675	1.87087417991267	0.335844467910651	0.518740911289018	NA	NA	0.580471888061272	0.134445407485522	79.5737194406837
a6183	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	25	1.6094379124341	NA	1.01378377749204	1.41816510957387	-0.404381332081833	1.56363044872881	1.30535324097704	0.298788164732849	0.258616946485395	0.309786898586286	0.518769682758434	NA	NA	0.58047228020045	0.576657415303786	79.5737194406837
a6184	loss_cnaOV36	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.20393852499657	3.46819901783082	0.735739507165758	0.464246591058762	1.76633965690683	0.430584771018141	1.58480325184042	0.416533425091167	0.518774181932718	NA	NA	0.698247957813632	0.113544830710142	79.5737194406837
a6185	loss_cnaOV84	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	4.30653387499886	3.82718532118266	0.479348553816198	1.88425736134006	1.44166999828482	0.307833784981154	0.254396540329975	0.332495338313544	0.518934875147686	NA	NA	0.742619890092577	0.624147765686548	79.5737194406837
a6186	loss_cnaOV1	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	3.53150123730429	3.90190451600934	-0.370403278705053	0.383208731343168	0.920922718984161	0.419046585605896	0.96658360942552	0.402208861904974	0.519004271949667	NA	NA	0.939777311767978	0.26320951581871	79.5737194406837
a6187	loss_cnaOV20	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	2.45755732901234	1.80091380620609	0.656643522806245	0.943249061368559	1.42184976104387	0.47946788771003	0.696150730172498	0.461823422415713	0.519059024382335	NA	NA	0.0341128580555783	0.2269130063904	79.5737194406837
a6188	KRAS_mut	151	QS11	ARFGAP	3	16	2.32630161961136	NA	2.86265907756886	3.93630205108665	-1.07364297351779	2.18425028499476	1.28335012148892	0.756440735890372	0.491538438105486	0.8365939703751	0.5190596621389	NA	NA	0.0641973258481983	0.487118934617458	79.5737194406837
a6189	gain_cnaOV94	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	0.852830507733587	1.43803382417796	-0.585203316444377	1.57036614156389	1.45504134317088	0.397842959843561	0.372654058792676	0.402190164005291	0.519174337514286	NA	NA	0.856225825597339	0.597691097361987	79.5737194406837
a6190	loss_cnaOV87, loss_cnaOV88	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.45211750557234	3.98930083640353	0.462816669168814	0.909731668660015	1.53717301493445	0.307823732756912	0.508739758230598	0.301083004107089	0.519248681290757	NA	NA	0.329290906239346	0.489988195017052	79.5737194406837
a6191	loss_cnaOV33_(ZFHX3)	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.402154040437479	-0.0149696067196404	-0.387184433717839	1.35484882126279	0.909484212763885	0.401922466642443	0.285776853949626	0.425718696689854	0.519322429898087	NA	NA	0.548567849192132	0.613986304713248	79.5737194406837
a6192	loss_cnaOV56	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	2.82994090412975	3.27105376234851	-0.441112858218757	0.799622751344565	1.25933126540004	0.357459043097894	0.551651209869937	0.350275475832512	0.519327703328786	NA	NA	0.600584907084001	0.454037971869244	79.5737194406837
a6193	KRAS_mut	1268	XAV 939	TNKS1 (tankyrase-1)	6	26	1.6094379124341	NA	3.20230195006009	2.77591513836828	0.426386811691812	0.829596989317071	1.10898953900752	0.399420249696799	0.513968610280054	0.384482266688831	0.519376938125635	NA	NA	0.306366586866066	0.315249144291394	79.5737194406837
a6194	loss_cnaOV55	1371	PLX4720 (rescreen)	BRAF	8	25	2.30258509299405	NA	4.40838905362168	4.56664029573613	-0.158251242114457	1.14817707621923	0.943965599116205	0.159246094678146	0.137828254362606	0.16764513692302	0.519491055437268	NA	NA	0.325079382056406	0.730914913694062	79.5783536232485
a6195	loss_cnaOV20	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	4.37033722653856	3.84212766435982	0.528209562178741	1.66992556131234	1.53111957572275	0.339354095629555	0.316307250104991	0.344982567367022	0.51974017371834	NA	NA	0.742632657108923	0.595148904187618	79.5861921054689
a6196	gain_cnaOV94	300	CX-5461	RNA Pol I	6	25	2.32630161961136	NA	3.17912125692102	3.62586642130906	-0.446745164388032	1.73033718975021	1.71027031127065	0.260683283615937	0.258183877127743	0.261213190361775	0.519982783565777	NA	NA	0.698260453109782	0.585785249732708	79.5861921054689
a6197	loss_cnaOV33_(ZFHX3)	272	AR-42	HDAC	4	26	1.63315443905142	NA	-0.357271357179662	0.395462256786435	-0.752733613966097	0.468282456006581	1.94124311250928	0.40893976325632	1.60743500917215	0.387758549722863	0.520157751488533	NA	NA	0.485633935504304	0.106505328962292	79.5861921054689
a6198	loss_cnaOV38	1175	AG-014699	PARP1, PARP2	8	25	1.6094379124341	NA	4.1908261311327	3.808464108874	0.3823620222587	1.3824021986455	0.960148734002465	0.357294308139475	0.276592458137975	0.398232074592017	0.520401371357031	NA	NA	0.315999473842179	0.484527658186464	79.5861921054689
a6199	loss_cnaOV40	1264	SGC0946	Q8TEK3 (DOT1L)	8	25	-0.693147180559945	NA	2.30138056829821	2.05577026220978	0.245610306088425	0.625769127321454	0.529978313342977	0.444092925986298	0.392493485800005	0.463434634785665	0.520512436693083	NA	NA	0.0421580443957489	0.3394223375746	79.5861921054689
a6200	loss_cnaOV57_(ZNRF3)	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.32979681248315	-1.14531831497255	-0.184478497510602	1.45181686459907	1.32341011596217	0.13741352745859	0.127067333359257	0.139396318106937	0.520529463331737	NA	NA	0.0490029075401437	0.825824327315803	79.5861921054689
a6201	gain_cnaOV49	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.457418360907965	0.37871067890565	-0.836129039813615	0.803443079828277	1.89791467824033	0.454062868076744	1.04068235921868	0.440551437532925	0.520587571010373	NA	NA	0.485640878939747	0.21481524018175	79.5861921054689
a6202	loss_cnaOV52, loss_cnaOV53	192	LFM-A13	BTK	5	14	2.77258872223978	NA	4.90379390421888	4.66126074864844	0.242533155570437	0.46528141335927	0.746550230645548	0.35111509892643	0.521261216560061	0.32487185136989	0.520755020855924	NA	NA	0.956836617000935	0.41704949684113	79.5861921054689
a6203	gain_cnaOV4_(KRAS)	185	OSI-906	IGF1R	6	12	0.940007258491471	NA	2.52304965805655	2.05062094375258	0.472428714303969	0.823155666991339	1.47152068394108	0.362289464595671	0.57392390437001	0.321047960426009	0.520764821374889	NA	NA	0.685342636449787	0.396303544607059	79.5861921054689
a6204	gain_cnaOV26	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.62483163377917	3.9896990475866	0.635132586192571	1.54113864613248	1.78640430614221	0.358607028302201	0.412119044439284	0.355536864756086	0.520765873861058	NA	NA	0.621901667787592	0.558305203605521	79.5861921054689
a6205	ARID1A_mut	346	THZ-2-102-1	CDK7	8	24	0.916290731874155	2.99573227355399	-1.04836323253889	-1.06310321415777	0.0147399816188791	2.07169278986889	1.96386596966782	0.00740870749348609	0.00711494565746495	0.00750559449908507	0.521274149190231	NA	NA	0.443193365950003	0.986217935400271	79.5861921054689
a6206	loss_cnaOV83	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.65809159544849	2.18411075799592	0.473980837452565	2.04744592133523	1.19977753819055	0.338940756028267	0.231498586855696	0.395057268839522	0.521276174563243	NA	NA	0.746465149864116	0.683774935833974	79.5861921054689
a6207	PIK3CA_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	7	26	-2.30258509299405	NA	-0.0438739919330058	-0.41029159990732	0.366417607974314	1.19603405682335	1.45700199494733	0.25982162962492	0.306360513635803	0.251487375614445	0.521281495883736	NA	NA	0.888879436562122	0.507034732530447	79.5861921054689
a6208	loss_cnaOV42	305	TPCA-1	IKK	4	28	2.99573227355399	NA	2.94838041645367	3.37902566785954	-0.430645251405861	1.10003413287581	1.24573029280703	0.34956778803858	0.391483535406333	0.345697021170996	0.521721829508707	NA	NA	0.993606082426983	0.509807594261034	79.5861921054689
a6209	loss_cnaOV87, loss_cnaOV88	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.15601681153597	0.717117594384355	0.438899217151618	1.08390637330538	1.04569263776999	0.418683678744978	0.404923550558332	0.419721055020143	0.52177332120206	NA	NA	0.771739975571396	0.561623455332819	79.5861921054689
a6210	gain_cnaOV72_(ASXL1)	172	Embelin	XIAP	4	15	3.46573590279973	NA	2.86707883241595	3.15955604817724	-0.292477215761292	0.645926168794882	1.01690823222992	0.304063741870434	0.452802858733797	0.287614168605889	0.521777251553043	NA	NA	0.670405310247774	0.503288415762329	79.5861921054689
a6211	gain_cnaOV50	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	0.893730963064945	0.277594328547095	0.61613663451785	1.08046890814307	1.73184610539699	0.367570276294621	0.570249296277077	0.355768698268148	0.52193177601466	NA	NA	0.837069902050871	0.371598119379109	79.5861921054689
a6212	PIK3CA_mut	330	XMD13-2	RIPK	6	26	2.32630161961136	NA	3.8034468789872	4.14877034795392	-0.34532346896672	1.05592167337611	1.1334724730857	0.30807146842233	0.327035117919886	0.30465977530679	0.521935242390188	NA	NA	0.819482432504225	0.496958198813389	79.5861921054689
a6213	gain_cnaOV94	291	KIN001-266	MAP3K8 (COT)	7	25	2.99573227355399	NA	3.06804298500112	3.3680726902779	-0.30002970527678	0.892543025910444	1.15649966919339	0.27060250795251	0.336151531709895	0.259429131947818	0.522027440267397	NA	NA	0.950884482009416	0.477004659104335	79.5861921054689
a6214	loss_cnaOV42	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	1.09872673163237	0.709626919472312	0.389099812160056	0.892392270108531	1.06408863986425	0.371212787253839	0.436018806071386	0.365664849320911	0.522034448377103	NA	NA	0.771741975768426	0.467977756201514	79.5861921054689
a6215	ARID1A_mut	341	EX-527	SIRT1	8	23	2.99573227355399	NA	5.51105117337442	5.86453483732995	-0.353483663955528	0.452909141034663	0.573024856118856	0.646867946559778	0.780473679882019	0.616873177805412	0.522039837916177	NA	NA	0.110363306110531	0.0965936489413631	79.5861921054689
a6216	loss_cnaOV83	290	KIN001-260	IKK	5	26	2.99573227355399	NA	5.11747915827422	4.79885551021984	0.318623648054377	1.12256021619677	0.860800892911273	0.353462297973237	0.283836575942333	0.370147906070096	0.522264517668227	NA	NA	0.66508716341883	0.573965318937022	79.5861921054689
a6217	SMAD4_mut	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.78337692477081	4.34624054061717	0.437136384153639	1.4789954060073	0.939617956603804	0.443878705921074	0.295563043927049	0.465227788678756	0.522269833773906	NA	NA	0.511128823882499	0.662267163875226	79.5861921054689
a6218	loss_cnaOV58	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	0.461750464165202	0.05198241326886	0.409768050896342	2.19298342787283	1.52011305128512	0.251464562777056	0.186854148411788	0.269564194945843	0.52243294149686	NA	NA	0.461492335613235	0.70661481737889	79.5861921054689
a6219	gain_cnaOV72_(ASXL1)	306	TG101348	JAK2	5	27	2.32630161961136	NA	2.42127943602472	2.8986473556918	-0.477367919667075	1.00556960041511	1.44785213571935	0.341710539935582	0.474723897251879	0.329707646167818	0.522470283481772	NA	NA	0.627166046649906	0.394961572670883	79.5861921054689
a6220	loss_cnaOV43_(NF1)	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	3.76397914062456	3.30308661429604	0.460892526328514	1.39275589228023	1.71280561051636	0.275378019691881	0.330921253956384	0.269086301153328	0.522511374735374	NA	NA	0.629482441654787	0.535620164096277	79.5861921054689
a6221	loss_cnaOV83	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-4.78953277562176	-4.02348260568626	-0.766050169935501	1.09171741271042	2.49715273386171	0.326194131857241	0.701692728371544	0.306769449680736	0.52252690917968	NA	NA	0.927979258568489	0.291014805065222	79.5861921054689
a6222	loss_cnaOV55	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	0.986784722306869	1.56339186741243	-0.576607145105562	1.36544141502805	1.88289358672151	0.322457941305031	0.422286257586317	0.306234589767523	0.522537800119358	NA	NA	0.614336154993572	0.38599991330252	79.5861921054689
a6223	gain_cnaOV72_(ASXL1)	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	2.88661541215717	2.37926993873422	0.507345473422953	2.38139685344628	1.47687809792284	0.318955462332711	0.2130453278666	0.343525626208766	0.522628912041094	NA	NA	0.226891140811689	0.751002863121707	79.5861921054689
a6224	gain_cnaOV50	272	AR-42	HDAC	4	26	1.63315443905142	NA	-0.353962432019546	0.394953191377186	-0.748915623396732	0.687866051813841	1.93358612103509	0.40682293910164	1.08875212175671	0.387319507132076	0.522654085895421	NA	NA	0.485674120504363	0.168168386161691	79.5861921054689
a6225	loss_cnaOV39	1008	Methotrexate	Dihydrofolate reductase (DHFR)	10	21	-1.6094379124341	NA	0.838807400920903	0.435657941714002	0.403149459206901	1.24736963240801	1.18848098360974	0.33399171139389	0.32319967452521	0.339214059599362	0.522674312054344	NA	NA	0.430528374169659	0.404960024425008	79.5861921054689
a6226	SMARCA4_mut	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-3.29586590171535	-4.24619004870812	0.950324146992771	3.28028021011896	2.26097458158974	0.40465158020269	0.289708221895564	0.420316156904594	0.522693439171493	NA	NA	0.927979702069307	0.668969791485876	79.5861921054689
a6227	loss_cnaOV52, loss_cnaOV53	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	8	24	1.63315443905142	NA	2.88454814436374	2.85684039023091	0.0277077541328317	0.752897681981182	0.826386670123985	0.0342140334252247	0.0368014868367256	0.0335288009046354	0.522734740097533	NA	NA	0.0193957652012151	0.931267165903522	79.5861921054689
a6228	loss_cnaOV39	1042	BIRB 0796	p38, JNK2	10	23	2.30258509299405	NA	4.24327748807706	4.46455120661804	-0.221273718540985	1.04250158625583	0.774885623612789	0.256939257843304	0.212252644464259	0.285556618677901	0.522737257542154	NA	NA	0.869418300614957	0.556676729648146	79.5861921054689
a6229	loss_cnaOV57_(ZNRF3)	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.69605373333984	3.21621049655672	0.479843236783124	0.911559426452798	1.05000383782305	0.462726309614947	0.526398195069262	0.456991888503924	0.522793885509322	NA	NA	0.0916744435876346	0.386309374641293	79.5861921054689
a6230	loss_cnaOV83	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	-0.641273636167677	-1.13685240071331	0.495578764545631	1.34842435739739	2.06100488391604	0.250183562956207	0.367524334477428	0.240454920031048	0.522801613759898	NA	NA	0.443217184025394	0.511787964171216	79.5861921054689
a6231	loss_cnaOV38	134	Etoposide	TOP2	4	15	2.77258872223978	NA	1.63289885961034	2.45675397574952	-0.823855116139179	3.6687008432917	1.06497613095871	0.452885911512132	0.224563176811109	0.773590216897661	0.52287426050729	NA	NA	0.408338619682246	0.685796588024846	79.5861921054689
a6232	loss_cnaOV35	308	XL-880	MET	5	27	1.63315443905142	NA	-0.0620819764920723	0.31146513722704	-0.373547113719112	0.696916465879233	1.00443424786315	0.385463107454433	0.535999839303328	0.371898025693373	0.522884015788304	NA	NA	0.367904946054729	0.340155249718532	79.5861921054689
a6233	gain_cnaOV26	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	2.76944356360797	3.00821655260968	-0.238772989001709	1.42131251141623	0.977332519542103	0.235971490357742	0.167994714099709	0.244310901589132	0.52305744393373	NA	NA	0.0874755745475748	0.800782720610981	79.5861921054689
a6234	TP53_mut	178	BAY 61-3606	SYK	12	7	2.07944154167984	NA	2.86370648251374	2.44371352702355	0.419992955490189	1.44359640915815	1.1025868012169	0.315017439234677	0.290935162228004	0.38091600137663	0.523121773108728	NA	NA	0.941035279364163	0.486641920011999	79.5861921054689
a6235	loss_cnaOV55	226	GSK1070916	AURKB	7	25	0.940007258491471	2.32630161961136	2.60235878735295	2.23322098784558	0.369137799507361	1.07968734939559	1.52579041331495	0.254998139482726	0.34189323391999	0.241932179076527	0.523145952418078	NA	NA	0.820800979034937	0.481148267801267	79.5861921054689
a6236	loss_cnaOV81_(RB1)	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-4.46894894829253	-4.14265836185865	-0.326290586433883	1.2124933313183	1.35981798431018	0.242448959730585	0.269107118369979	0.239951662795081	0.523146967068611	NA	NA	0.217367746468129	0.645263893379174	79.5861921054689
a6237	NF1_mut	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	2.02904103579143	1.63426069137667	0.394780344414762	1.19471142243908	1.51956950113521	0.264904581123717	0.330439917958424	0.259797491407821	0.523148992544524	NA	NA	0.326051193996331	0.579981202383924	79.5861921054689
a6238	ARID1A_mut	203	BMS-345541	IKBKB	8	24	2.77258872223978	NA	2.7724118348333	3.44411725659504	-0.671705421761747	0.494467943813532	1.11604491604472	0.667718979470378	1.35844078502095	0.601862355273548	0.523466313911376	NA	NA	0.0916815936873977	0.0269357136475582	79.6149368453779
a6239	loss_cnaOV41	333	T0901317	LXR	5	27	2.32630161961136	NA	5.21535869685758	4.66779490965952	0.547563787198063	1.04495941128792	1.11965085033341	0.493308520815562	0.524004838162267	0.48904869498827	0.523505759377972	NA	NA	0.0050809681449899	0.329304582335532	79.6149368453779
a6240	loss_cnaOV81_(RB1)	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	0.907283363514549	0.601641946784252	0.305641416730297	0.284547678577972	0.639706937923306	0.498181795627649	1.0741307687265	0.477783495240036	0.523874457675532	NA	NA	0.0150267276296916	0.138411936643012	79.6575802493348
a6241	loss_cnaOV16, loss_cnaOV17	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	6	27	0.693147180559945	NA	3.02929759435178	2.74643704290561	0.282860551446164	1.22335943408596	0.904959377283325	0.293588932211995	0.231216226045213	0.312567125714866	0.524221873503616	NA	NA	0.966168611300307	0.611222456906652	79.6575802493348
a6242	loss_cnaOV55	1008	Methotrexate	Dihydrofolate reductase (DHFR)	7	24	-1.6094379124341	NA	0.897058945610374	0.469061590247102	0.427997355363272	1.08921438606798	1.23786406966022	0.354123652931319	0.392941335367708	0.345754728530697	0.524444170544799	NA	NA	0.430557112539619	0.394608670583584	79.6575802493348
a6243	loss_cnaOV81_(RB1)	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	4.13445177601707	4.4233321195765	-0.28888034355943	0.912220755534451	0.996782743750214	0.29219616375604	0.316678108677961	0.28981274542592	0.524447596558055	NA	NA	0.511160231882263	0.589008695302418	79.6575802493348
a6244	loss_cnaOV83	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	2.91897750966185	2.6784540806077	0.240523429054156	0.869706416285654	0.50456351556869	0.424201822022562	0.276557036432346	0.47669603852166	0.524461673838653	NA	NA	0.135315226283907	0.577365468239882	79.6575802493348
a6245	SMAD4_mut	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	2.77644022847258	2.38337443384976	0.39306579462282	1.34675832582512	0.757641661549772	0.463273563040426	0.291860675434846	0.518801716656916	0.524689986637052	NA	NA	0.621371741830981	0.667213075151998	79.6575802493348
a6246	ARID1A_mut	268	YM155	BIRC5 (Survivin)	8	22	1.63315443905142	NA	-3.7538165334518	-4.29564530693868	0.541828773486876	2.4977509796256	2.30400686974131	0.230179679384444	0.216926658384534	0.235168037301777	0.5248203653186	NA	NA	0.927985344288233	0.601930662069113	79.6575802493348
a6247	SMAD4_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.25431836627375	1.19012471283452	1.06419365343923	3.22895416582468	2.24599235044511	0.457817894731279	0.329578432763983	0.473818912708376	0.524897965126986	NA	NA	0.363122001736993	0.628870668779967	79.6575802493348
a6248	loss_cnaOV35	1053	MK-2206	AKT1, AKT2	5	27	1.38629436111989	0.693147180559945	1.7711951826186	1.22446498614973	0.546730196468869	1.26566002549127	1.20199102793062	0.451591700863177	0.431972398161706	0.45485380819367	0.524972541094887	NA	NA	0.097270049543792	0.409166899366437	79.6575802493348
a6249	MLL2_mut	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.0975559462151	1.66794853561988	-0.570392589404778	1.03196459093072	0.633616194624173	0.854381407122125	0.552724962094236	0.900217819942408	0.524993238532723	NA	NA	0.208729767593902	0.440442508769069	79.6575802493348
a6250	SMARCA4_mut	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	1.43543504252273	1.99147274040909	-0.556037697886359	1.33282924762585	1.3432985412172	0.414148966463471	0.417185996538433	0.413934565418731	0.525121253682063	NA	NA	0.838931882885368	0.551393218626724	79.6575802493348
a6251	gain_cnaOV18_(CCNE1)	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.27879185976047	2.97386600101454	0.304925858745932	1.47980680902266	1.03282888126439	0.280820693782611	0.206057883290401	0.295233667723003	0.525130586978123	NA	NA	0.434195927200151	0.713805718986863	79.6575802493348
a6252	loss_cnaOV40	282	EKB-569	EGFR	7	25	0.916290731874155	2.99573227355399	2.09567147476672	1.56823052713381	0.527440947632901	1.03712392173705	1.5705337040179	0.356542963075267	0.508561162825659	0.335835484640379	0.52519190413277	NA	NA	0.32608452989801	0.310706401773249	79.6575802493348
a6253	loss_cnaOV85	228	KIN001-102	AKT1	7	25	2.32630161961136	NA	2.67572435001313	2.82053827244226	-0.144813922429136	1.10379095291989	1.2685410506611	0.11703580555927	0.131196873870053	0.114157852718811	0.52544118966881	NA	NA	0.0945529409112291	0.772369650982196	79.6575802493348
a6254	loss_cnaOV40	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	7	24	2.30258509299405	NA	1.80096656474288	1.29470866771867	0.506257897024204	2.11168258288217	1.23928765699689	0.346016696628283	0.23974147493949	0.408507172782624	0.52546191282996	NA	NA	0.476114544249078	0.563854981835684	79.6575802493348
a6255	loss_cnaOV54	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	22	1.38629436111989	0.693147180559945	3.05479795593693	2.70220903943483	0.352588916502097	1.90487085402391	1.37145904078505	0.225507031900738	0.185098593827123	0.257090373111157	0.525485131460863	NA	NA	0.968789667691817	0.592178406412913	79.6575802493348
a6256	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	291	KIN001-266	MAP3K8 (COT)	7	25	2.99573227355399	NA	3.5436468154377	3.23490361775566	0.308743197682039	0.571858896430383	1.20568875851392	0.278570955171561	0.539894018628117	0.256072054667395	0.525527180363721	NA	NA	0.950890377846995	0.350836543626216	79.6575802493348
a6257	gain_cnaOV96	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.77062206230928	4.4478401094652	0.322781952844085	0.301241450222787	0.703390972247033	0.479597793685332	1.0715057725468	0.458894079650944	0.525624447700846	NA	NA	0.053249014091854	0.144990674101089	79.6575802493348
a6258	loss_cnaOV1	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.39495117900924	4.09866287018592	-0.703711691176682	0.791477018778838	1.53296605519333	0.470704195379143	0.889111969747943	0.459052363744566	0.525663601792432	NA	NA	0.329396189193328	0.264434206387996	79.6575802493348
a6259	NF1_mut	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.35068911490994	3.72870364530438	-0.37801453039444	0.93398883469718	1.06626200405291	0.358721723598679	0.404731316212148	0.35452311810567	0.525838619344152	NA	NA	0.83086418897012	0.496731268712639	79.6575802493348
a6260	loss_cnaOV21, loss_cnaOV22	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.23662099185018	3.64079293873798	0.5958280531122	1.06966930754935	1.23127940229946	0.487784574173898	0.55702079970609	0.483909705627714	0.525983289335636	NA	NA	0.19786788117064	0.44165511383539	79.6575802493348
a6261	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.8326567458112	2.34837705394394	-0.515720308132743	1.00141702417892	1.27441544077647	0.410118110129309	0.514990554065717	0.404672049342504	0.526289013801217	NA	NA	0.844405618557706	0.475629957637241	79.6575802493348
a6262	gain_cnaOV26	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.8164020192295	4.45706059792272	0.359341421306782	0.696836832244545	0.697813402678663	0.514999921212261	0.515675126054009	0.514953453068392	0.526515088317796	NA	NA	0.0812637523222155	0.470413885760751	79.6575802493348
a6263	loss_cnaOV55	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	0.0950865629775137	-0.107734843629698	0.202821406607212	0.881566574867003	0.989043635666493	0.20941745915476	0.230069302069228	0.205068208614006	0.526547538421016	NA	NA	0.548666726830578	0.611406062470518	79.6575802493348
a6264	gain_cnaOV51_(MYC)	1061	SB590885	BRAF	8	25	1.6094379124341	NA	4.12168552288316	3.86541320069559	0.256272322187562	1.35090279709932	1.27034901926269	0.198818122289929	0.189704487056977	0.201733789928301	0.526826290128555	NA	NA	0.572890064357389	0.644758694636147	79.6575802493348
a6265	gain_cnaOV18_(CCNE1)	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	1.68097188667962	2.26147697818893	-0.580505091509305	2.55066525942792	1.22381861835836	0.376165052402223	0.227589680521036	0.474339156800868	0.526826378447162	NA	NA	0.947645022705774	0.685405720720793	79.6575802493348
a6266	loss_cnaOV34	1066	AZD6482	PI3Kbeta	5	28	1.6094379124341	NA	2.86437963394325	2.29245900520526	0.571920628737984	1.88602183995018	1.18956106516561	0.439750910775086	0.303241784704408	0.48078290849101	0.526920151451727	NA	NA	0.109813123366457	0.543773455799922	79.6575802493348
a6267	loss_cnaOV56	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.594314679143709	-0.238358684095276	0.832673363238985	2.12492649484141	1.55632656626151	0.519760580728484	0.391859843274781	0.535024834305289	0.527033091955792	NA	NA	0.100344895857705	0.570743399225617	79.6575802493348
a6268	loss_cnaOV33_(ZFHX3)	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.69299518727702	3.21664743170855	0.47634775556847	0.902864030460528	1.05104440497361	0.459272256515591	0.527596337319471	0.453213730375577	0.5270396166809	NA	NA	0.0917193225136914	0.385740982073149	79.6575802493348
a6269	loss_cnaOV54	1007	Docetaxel	Microtubules	10	21	-4.38202663467388	NA	-4.70099840292912	-4.62361145335692	-0.0773869495721984	0.801483388100504	1.63913600663162	0.0540190872107545	0.0965546519380814	0.0472120368652181	0.527146686880624	NA	NA	0.135175548700589	0.861109034165509	79.6575802493348
a6270	SMAD4_mut	305	TPCA-1	IKK	3	29	2.99573227355399	NA	2.88695797748145	3.37052987701508	-0.483571899533629	1.50388401428991	1.21037205507756	0.392472474761013	0.321548666611739	0.399523351109295	0.527149177594821	NA	NA	0.993607271571888	0.637909156885381	79.6575802493348
a6271	loss_cnaOV44	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.537198672207754	0.188281824372844	-0.725480496580598	1.72356564597681	1.61408058685229	0.447311518502647	0.420918401497518	0.449469811166862	0.527267003553821	NA	NA	0.461568395547881	0.547364453061211	79.6575802493348
a6272	gain_cnaOV95_(MECOM)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	8	23	0.693147180559945	NA	0.193083959686048	-0.279816121509782	0.47290008119583	1.97188230927588	1.47342925331238	0.294100237301857	0.239821656176575	0.320952010510661	0.527344685353973	NA	NA	0.100348445734565	0.548857433782191	79.6575802493348
a6273	loss_cnaOV84	1023	GW 441756	NTRK1	6	25	0.693147180559945	NA	1.98539243843708	2.37360692468966	-0.388214486252576	1.11810244117207	1.28449058894501	0.30875001044019	0.347208334368381	0.302232254244406	0.527523930074749	NA	NA	0.844412294775787	0.478587149029665	79.6575802493348
a6274	gain_cnaOV26	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.464836007598205	-1.40559523236767	0.940759224769469	0.992805072986522	1.91310614716729	0.504177646062905	0.947576971922101	0.491744394926772	0.527597254058217	NA	NA	0.073948465306193	0.239160605734914	79.6575802493348
a6275	gain_cnaOV26	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.73487534355392	4.87301442253348	-0.138139078979556	0.55212964089767	0.628952700815529	0.221332242012614	0.25019319512527	0.219633493584555	0.527602475072277	NA	NA	0.0495153582140532	0.715552242480465	79.6575802493348
a6276	gain_cnaOV49	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.14081023803043	4.55139921403456	-0.410588976004123	0.331208893460773	0.950456358379106	0.44570519208343	1.23966772665406	0.431991403271093	0.527633136333119	NA	NA	0.528146258219634	0.163462669089469	79.6575802493348
a6277	loss_cnaOV81_(RB1)	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	0.179421300475717	-0.0980517982786685	0.277473098754386	0.283175764947391	1.01570744311916	0.286723756303921	0.97986174348619	0.273182106357603	0.527788424719101	NA	NA	0.548683464981701	0.260262696716481	79.6575802493348
a6278	loss_cnaOV40	1495	AZD-2281	PARP1, PARP2	8	25	2.30258509299405	NA	3.48907895132347	3.5843267186305	-0.0952477673070287	1.33548339328981	0.762724820511662	0.103121875381309	0.0713208174550164	0.124878284730702	0.527828731520982	NA	NA	0.142663721041261	0.85227794957067	79.6575802493348
a6279	loss_cnaOV59	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.64568609855204	4.36326580133715	0.282420297214886	1.05128039351798	0.839567120481651	0.327508303516494	0.268644120974997	0.336387991293494	0.527873879679362	NA	NA	0.869440233093881	0.636883979416737	79.6575802493348
a6280	loss_cnaOV39	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	10	23	0.693147180559945	NA	2.64236776921761	2.86547426227766	-0.223106493060054	1.13471714286598	0.885062467114659	0.23138424854848	0.196618597385908	0.252079939382573	0.527920370603505	NA	NA	0.966172728423993	0.589043819505338	79.6575802493348
a6281	loss_cnaOV35	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	3.19483407665707	2.93466547978491	0.260168596872159	0.915745804363164	0.546603329682164	0.432245993164436	0.284105693558801	0.475973311438553	0.527950224024792	NA	NA	0.849345815565423	0.675662906640909	79.6575802493348
a6282	loss_cnaOV33_(ZFHX3)	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	1.09419568757334	0.710274211480745	0.383921476092591	0.888873110765939	1.06465958997793	0.366194681258635	0.431919327339948	0.360604910439543	0.527993299549667	NA	NA	0.771787137720251	0.472108627658037	79.6575802493348
a6283	loss_cnaOV33_(ZFHX3)	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	4.13627835468276	3.75308909303758	0.383189261645187	1.50073998333019	0.965278997030828	0.371519361314775	0.255333546051647	0.396972546614882	0.5281625480405	NA	NA	0.717019224056587	0.650381104945284	79.6575802493348
a6284	loss_cnaOV42	1030	KU-55933	ATM	4	29	2.30258509299405	NA	4.50729831522753	4.10184942470355	0.405448890523981	1.51780405098391	0.962257020529663	0.393941863962828	0.267128612722538	0.421351969249138	0.528311488592714	NA	NA	0.529435969057473	0.635557589257242	79.6575802493348
a6285	gain_cnaOV72_(ASXL1)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	2.53991610871721	2.84392875646344	-0.304012647746225	1.1578023643883	0.93123635287857	0.315539580640032	0.262577325022862	0.326461318661458	0.52834469957145	NA	NA	0.966173197459433	0.602379735921667	79.6575802493348
a6286	loss_cnaOV57_(ZNRF3)	219	AT-7519	CDK9	4	28	2.32630161961136	NA	2.11805599124514	1.40908652246326	0.708969468781872	1.73891221092862	1.69741737323741	0.416645689753527	0.407708603301638	0.417675393194359	0.528365145887102	NA	NA	0.315817342426194	0.48830795174666	79.6575802493348
a6287	loss_cnaOV54	1262	UNC1215	LMBL3	11	22	0	NA	2.91126532913523	2.71498639224167	0.19627893689356	0.453177598233596	0.505998937196582	0.400910554210425	0.433117033274856	0.387903852093082	0.528410743986487	NA	NA	0.109501353010348	0.271572753119087	79.6575802493348
a6288	gain_cnaOV4_(KRAS)	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	6.09521584534817	5.74599181114376	0.349224034204411	1.02875981724381	1.34576169974608	0.271007240065162	0.339461192351029	0.259499162645439	0.528415683015879	NA	NA	0.570718622763034	0.473957867380161	79.6575802493348
a6289	loss_cnaOV40	1239	YK 4-279	RNA helicase A	6	18	2.30258509299405	NA	1.46216236250361	1.60529141424339	-0.143129051739783	0.368516181397161	1.19536339021373	0.134347012627397	0.388392854818846	0.119736854007376	0.528471773347336	NA	NA	0.286576276103385	0.658451407603569	79.6575802493348
a6290	gain_cnaOV19	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	1.73498381629506	2.35370212559274	-0.618718309297685	0.762903444391352	1.44692643957048	0.438669471793954	0.811004739651296	0.427608683051884	0.528479900528229	NA	NA	0.529658875765744	0.301898695958239	79.6575802493348
a6291	loss_cnaOV39	286	KIN001-236	TIE2	9	23	2.32630161961136	NA	4.69056075098431	4.83596589535119	-0.145405144366876	0.843031804499277	0.589027671753364	0.218228319834433	0.172478836018814	0.246856219732508	0.528493553105486	NA	NA	0.761950136895731	0.644517464945086	79.6575802493348
a6292	loss_cnaOV87, loss_cnaOV88	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.31746482265769	3.87725674938811	0.440208073269582	0.731823671886999	1.25314561374584	0.359547313797993	0.601522047154488	0.351282459469124	0.528519511298577	NA	NA	0.698569516231059	0.422730029696558	79.6575802493348
a6293	gain_cnaOV94	279	BIX02189	MAP2K5 (MEK5)	7	25	2.99573227355399	NA	4.24330561865412	4.48378869413985	-0.240483075485728	0.616270645589799	0.763970940257101	0.326387053991352	0.390223154723806	0.31478039649623	0.528712584158394	NA	NA	0.524101120350548	0.405290126638846	79.6575802493348
a6294	gain_cnaOV94	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	0.625242683054255	0.93757544143908	-0.312332758384825	1.3527273440122	1.22235144869911	0.249963114815193	0.230891139864478	0.255517968025665	0.528751037610759	NA	NA	0.844798652279465	0.595054035356738	79.6575802493348
a6295	gain_cnaOV19	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	3.23518941697091	2.87119881177997	0.363990605190934	0.835853536616291	1.27783120877736	0.290443177840821	0.435471753418001	0.284850301581853	0.528767901564486	NA	NA	0.231318989178702	0.545977130680038	79.6575802493348
a6296	gain_cnaOV51_(MYC)	294	MPS-1-IN-1	MPS1	8	23	2.99573227355399	NA	4.07102001690962	4.35787682037454	-0.286856803464921	0.820438569130265	0.814259126642776	0.35164577936856	0.349638369352887	0.352291787809176	0.528838665237389	NA	NA	0.316566462121423	0.409889600630013	79.6575802493348
a6297	loss_cnaOV55	1072	BMS-708163	g-secretase	8	25	1.6094379124341	NA	4.00263509564872	3.78977327135028	0.212861824298437	1.08709347405499	0.79078838622343	0.245629463503001	0.195808207278107	0.269176720354989	0.528942925097707	NA	NA	0.92370010877295	0.620241839900966	79.6575802493348
a6298	loss_cnaOV1	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.49779824817668	4.04121777848949	0.456580469687192	0.889870769731012	1.13585522172437	0.407247849426694	0.513086265127246	0.401970656959295	0.528989272112961	NA	NA	0.819525128091088	0.476748239939245	79.6575802493348
a6299	loss_cnaOV56	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.65240174877485	4.2617830500861	0.390618698688754	0.990887180579899	0.783166810083143	0.48874534024027	0.394211073010503	0.498768198115143	0.529295099804525	NA	NA	0.224822850384304	0.5692387188324	79.6575802493348
a6300	loss_cnaOV52, loss_cnaOV53	326	GSK690693	AKT	8	24	2.32630161961136	NA	4.04680850412735	4.18697203024877	-0.140163526121426	1.66289524030541	1.40419788856998	0.0954374934892341	0.0842888491855224	0.0998175024064214	0.529304883276458	NA	NA	0.0933738813847308	0.834406474765786	79.6575802493348
a6301	PIK3CA_mut	1133	JNJ-26854165	MDM2	7	26	2.30258509299405	NA	2.68898703371211	3.16985990058514	-0.480872866873032	0.698299883250717	0.946370923639265	0.532122954543918	0.68863374949238	0.5081230359697	0.529468884065661	NA	NA	0.238611019661525	0.160622626667884	79.6575802493348
a6302	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	8	23	0.693147180559945	NA	0.191387391485713	-0.279226010831404	0.470613402317117	1.84449065768315	1.52521067228331	0.292653143824919	0.255145451865964	0.308556326590994	0.529670124284467	NA	NA	0.100374822712123	0.530455996809905	79.6575802493348
a6303	loss_cnaOV40	310	YM201636	FYV1	7	25	1.63315443905142	NA	2.14673747655007	2.41576671818274	-0.269029241632672	1.24407364902897	0.743783004475095	0.310211249287883	0.21624864560282	0.361703937860925	0.52991507267924	NA	NA	0.650375208239385	0.601801734617128	79.6575802493348
a6304	KRAS_mut	310	YM201636	FYV1	7	25	1.63315443905142	NA	2.57227838235798	2.29661526455652	0.275663117801462	0.743498380384308	0.895054265152673	0.3179998964178	0.370764920374102	0.307984810009749	0.529927305760841	NA	NA	0.650375342049585	0.425036750314292	79.6575802493348
a6305	SMAD4_mut	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	1.99777279118059	1.37269926787517	0.625073523305429	1.10117284771393	1.8363221674137	0.348169691970857	0.567643421832551	0.340394258914704	0.530040473081031	NA	NA	0.614429487802765	0.445558009707679	79.6575802493348
a6306	loss_cnaOV84	333	T0901317	LXR	6	26	2.32630161961136	NA	5.18381186971411	4.65401480103116	0.52979706868295	0.811238045707865	1.15875529521169	0.477971549705651	0.653072265885488	0.457212209404542	0.530051626422672	NA	NA	0.00508956246918103	0.215575498408626	79.6575802493348
a6307	loss_cnaOV1	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.81433612523368	4.4572671873223	0.357068937911385	0.181214126677081	0.719944655667238	0.511667791425274	1.97042550963851	0.495967204007448	0.530153532268619	NA	NA	0.0812981401833038	0.0562852556422574	79.6575802493348
a6308	gain_cnaOV96	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.98278254897805	4.7603092447054	0.22247330427265	0.896087223168786	0.621247909050687	0.334801148398871	0.248271929919868	0.358107127656342	0.530217761869229	NA	NA	0.76196353088211	0.618722525812315	79.6575802493348
a6309	loss_cnaOV36	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	2.24377137654495	1.1912157807375	1.05255559580745	2.79575099948491	2.28763996118851	0.452717664920972	0.376484027369167	0.460105442143358	0.530278878042331	NA	NA	0.363208297487859	0.585569751419632	79.6575802493348
a6310	gain_cnaOV50	305	TPCA-1	IKK	4	28	2.99573227355399	NA	3.69294276517107	3.27265961804276	0.420283147128309	1.01621326505372	1.25407196019411	0.341040992499492	0.413577702221879	0.335134793272355	0.530356313225158	NA	NA	0.993607963950564	0.491388827937998	79.6575802493348
a6311	SMAD4_mut	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.14566468435406	0.802244388497359	0.343420295856697	1.24106171188442	1.36289701680862	0.254086791295688	0.276714922850411	0.251978169752587	0.530386725534387	NA	NA	0.163089469140137	0.634902792136263	79.6575802493348
a6312	loss_cnaOV52, loss_cnaOV53	1529	MLN4924	NEDD8-activating enzyme	6	11	0	NA	1.66755673095661	1.15323860690478	0.514318124051822	1.62134547685227	1.38312311808046	0.350631055305783	0.317216861794523	0.37185274205062	0.530481620052481	NA	NA	0.856341751007022	0.527285491063215	79.6575802493348
a6313	loss_cnaOV54	1529	MLN4924	NEDD8-activating enzyme	6	11	0	NA	1.66755673095661	1.15323860690478	0.514318124051822	1.62134547685227	1.38312311808046	0.350631055305783	0.317216861794523	0.37185274205062	0.530481620052481	NA	NA	0.856341751007022	0.527285491063215	79.6575802493348
a6314	loss_cnaOV44	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.90621483542805	3.32015826837351	0.586056567054543	0.976318306118266	1.7122596539156	0.350240536322425	0.600272025405976	0.342270849934674	0.53051240833679	NA	NA	0.629575353270818	0.423903625655972	79.6575802493348
a6315	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.20704074992549	4.47269084942398	-0.265650099498497	1.07645404851691	0.669957357557437	0.360338919646493	0.2467825727113	0.396517922374966	0.530526980443034	NA	NA	0.52412629272982	0.618782494710613	79.6575802493348
a6316	BRCA1_mut	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.10568120193216	3.80492026693856	0.300760934993603	0.99419631897767	0.850883439325835	0.347383310737369	0.302516645105742	0.353469019483914	0.530772520894744	NA	NA	0.923704631962804	0.598030176142739	79.6575802493348
a6317	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.28145772202492	2.86864651447167	0.412811207553244	1.10040385178925	0.819280925753135	0.485620545666051	0.375145185907898	0.503870155616967	0.530812770813658	NA	NA	0.32953168324556	0.587769637793553	79.6575802493348
a6318	loss_cnaOV33_(ZFHX3)	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.30491826790048	5.02730262937306	0.277615638527421	0.665009932902266	0.60963877485828	0.451114043441788	0.417460890119097	0.455377265975179	0.530889288287544	NA	NA	0.110389305375743	0.476952060703266	79.6575802493348
a6319	KRAS_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	7	25	2.30258509299405	NA	3.84289878156408	4.29618809500562	-0.453289313441533	0.853970140757642	0.987868120646353	0.470910926811827	0.530802298355977	0.458856100290948	0.53096094250146	NA	NA	0.0480233149874872	0.256275060950262	79.6575802493348
a6320	loss_cnaOV43_(NF1)	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	3.11050202265801	2.30133149898832	0.809170523669695	1.96273497513418	1.48661111510766	0.51629039473322	0.412266828645257	0.544305444407428	0.53098670713807	NA	NA	0.22708669605338	0.4829021225191	79.6575802493348
a6321	loss_cnaOV40	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.00817890505323	-3.57605691584259	0.567878010789366	2.15314615429946	1.68392897172578	0.319793604309313	0.263743364404414	0.337233945329283	0.531018472083431	NA	NA	0.68103149947717	0.650161478033822	79.6575802493348
a6322	PTEN_mut	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.83851891885544	3.96759346637182	0.870925452483621	0.719206859957273	1.81368757092645	0.494281924742244	1.21095264933285	0.480195964533595	0.531040028581065	NA	NA	0.622023214780092	0.160601507177095	79.6575802493348
a6323	loss_cnaOV39	293	MP470	PDGFR	9	23	2.99573227355399	NA	4.30148677609721	3.95053853462931	0.350948241467909	1.98676884457883	1.6899024601148	0.197836451238595	0.176642714337664	0.207673667416324	0.531100345486663	NA	NA	0.622023915837916	0.647774110161917	79.6575802493348
a6324	loss_cnaOV36	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.9864881380178	5.69957637788336	0.286911760134442	1.2152356218051	0.533293402254084	0.475620278649819	0.236095580960888	0.537999830715597	0.531142020299507	NA	NA	0.192116700580213	0.723396651730398	79.6575802493348
a6325	gain_cnaOV4_(KRAS)	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.64680107602538	4.47958986568446	0.167211210340912	0.697435195804781	0.572882696721186	0.278747751430662	0.239751608961983	0.291876873394714	0.531170609807533	NA	NA	0.614864019358388	0.576002314463766	79.6575802493348
a6326	loss_cnaOV41	281	CH5424802	ALK	5	27	1.63315443905142	NA	3.73955748643254	3.96242939045116	-0.222871904018619	1.06933681169116	0.663652208404203	0.304939730359101	0.208420678669189	0.335826357836628	0.531301329408854	NA	NA	0.955765192484934	0.672994633802176	79.6575802493348
a6327	loss_cnaOV83	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.32364910352832	0.758196445935645	0.565452657592671	0.945638653506492	1.38926511190643	0.421885306415023	0.597958486041084	0.407015660831449	0.531394362771284	NA	NA	0.163102760812064	0.290908231089571	79.6575802493348
a6328	gain_cnaOV48_(SOX17)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.00142660564015	1.81142463979905	-0.809998034158907	0.898475625970456	1.73948045315874	0.477075567995782	0.901524772343175	0.465655151621867	0.531506951790249	NA	NA	0.229038227364087	0.258235461891972	79.6575802493348
a6329	TP53_mut	155	AP-24534	ABL	12	7	-0.669430653942629	NA	0.920214820114234	0.562841161781944	0.35737365833229	1.34365925573315	1.09752518818227	0.283117434226562	0.26597045107042	0.325617728121736	0.531575683829531	NA	NA	0.583799467814528	0.538717664085956	79.6575802493348
a6330	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1054	PD-0332991	CDK4, CDK6	8	25	1.38629436111989	0.693147180559945	2.66103056750462	2.1635571856803	0.497473381824319	2.11589218841238	1.68550324075268	0.277647071473981	0.235112821224407	0.295148279633189	0.531635603399611	NA	NA	0.110374269271701	0.557821208962677	79.6575802493348
a6331	loss_cnaOV57_(ZNRF3)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.998572193633052	0.501577852247069	0.496994341385983	1.62895545441468	1.15247410549131	0.410571395724407	0.305100019794319	0.431241221835617	0.531647935710527	NA	NA	0.43067231633743	0.592288292492943	79.6575802493348
a6332	loss_cnaOV34	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	-0.652344400339402	-1.13480225920003	0.482457858860624	2.58689162207097	1.87083247016322	0.243503733402703	0.186500993989994	0.257884052449941	0.531727738158215	NA	NA	0.443353923443593	0.707561486510864	79.6575802493348
a6333	loss_cnaOV43_(NF1)	163	JQ1	BRD4	3	16	0.940007258491471	NA	0.642085032270012	-0.0152840031890956	0.657369035459108	3.07991517501383	1.64585067123185	0.351071486811861	0.213437383208502	0.399409889942868	0.531794916134418	NA	NA	0.581548396998825	0.750152824843929	79.6575802493348
a6334	gain_cnaOV96	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	4.35712341666499	3.84565134699278	0.511472069672212	0.959262031155657	1.65790177206939	0.328381911087093	0.533193280939123	0.308505653524812	0.531990366242963	NA	NA	0.742822566411873	0.447851658393736	79.6575802493348
a6335	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.587657504416377	-0.23764541537449	0.825302919790867	3.21829826649236	1.41089627869241	0.515045342469256	0.256440780639754	0.584949391570966	0.532146782065768	NA	NA	0.100402691266444	0.701606023787498	79.6575802493348
a6336	gain_cnaOV95_(MECOM)	1170	CCT018159	HSP90	8	25	2.30258509299405	NA	3.95099446298104	3.61302781735367	0.33796664562737	1.16052941500351	1.2433484024171	0.275860332661811	0.291217647099749	0.271819744948684	0.532299237011976	NA	NA	0.197957643417083	0.493996040726704	79.6575802493348
a6337	BRCA1_mut	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.77247199811717	4.49459420103131	0.277877797085857	0.524045801761013	1.02939579660898	0.28017271957824	0.530254790997412	0.269942618768445	0.532409865282173	NA	NA	0.325281951971734	0.420599905535064	79.6575802493348
a6338	gain_cnaOV18_(CCNE1)	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.39842579897874	2.9296939335586	0.468731865420148	0.898388885733892	1.01246364743758	0.467800048335838	0.521747177490115	0.462961674334135	0.532469180549192	NA	NA	0.0875685032135444	0.38867160847204	79.6575802493348
a6339	PIK3CA_mut	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.3886241075618	2.99418110817953	0.394442999382268	1.03995133906324	0.924039053949042	0.414077610466183	0.37928986152138	0.426868320875126	0.532541464156964	NA	NA	0.670612419274763	0.48036943156918	79.6575802493348
a6340	SMAD4_mut	292	Masitinib	KIT	3	29	2.99573227355399	NA	3.7758148222629	4.03811065466663	-0.262295832403728	0.665533760621336	1.07834271678586	0.248420236351092	0.394113488936836	0.243239768137475	0.532572764639133	NA	NA	0.104527729444302	0.584999025753663	79.6575802493348
a6341	PTEN_mut	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.76657664135006	4.23212846713719	0.534448174212871	0.940744946844284	0.799135231406679	0.660059531334551	0.568111660876489	0.668783146091692	0.532573253588526	NA	NA	0.316628174173911	0.431083565703949	79.6575802493348
a6342	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1043	JNK Inhibitor VIII	JNK	8	25	2.30258509299405	NA	4.65072202090596	4.3752566829861	0.275465337919861	1.01802667589278	1.00833439116329	0.272594617485978	0.270587543964196	0.273188478280568	0.532576510531492	NA	NA	0.3747083667258	0.51724286622346	79.6575802493348
a6343	loss_cnaOV84	1058	GDC0941	PI3K (class 1)	6	27	1.38629436111989	0.693147180559945	1.28622195628811	0.74557089874485	0.540651057543264	0.850758907392509	1.4140917732605	0.403665343749806	0.635492679354137	0.382330954586259	0.532683679239681	NA	NA	0.163119702633788	0.243697080314088	79.6575802493348
a6344	gain_cnaOV19	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.33554371489314	5.03370743273684	0.301836282156303	0.146366040848956	0.636416524954145	0.489996249169174	2.0622015899698	0.474274740395923	0.532711445928627	NA	NA	0.110410061448659	0.0570235039648007	79.6575802493348
a6345	PIK3CA_mut	269	NSC-207895	MDM4	6	25	2.99573227355399	NA	3.45200252103333	3.98888145840362	-0.536878937370294	1.56922460215329	1.59319600926805	0.337853325185994	0.342130079170048	0.336982351353585	0.532845868608923	NA	NA	0.715464915056414	0.475393246019821	79.6575802493348
a6346	MLL2_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	0.47398846286543	0.910142049267603	-0.436153586402173	0.679154932977965	1.280798533856	0.348997480261001	0.642200424709753	0.340532546589573	0.532899492265299	NA	NA	0.844819954818379	0.399383453687255	79.6575802493348
a6347	loss_cnaOV36	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.145394540522786	-0.380362772089658	0.525757312612444	1.38153670015621	1.4120621696378	0.372847718535819	0.380559787194213	0.372332977907979	0.533005384524749	NA	NA	0.88892187986294	0.584265047580206	79.6575802493348
a6348	loss_cnaOV16, loss_cnaOV17	1028	VX-702	p38	6	25	0.693147180559945	NA	3.58688544771256	3.26458932737572	0.322296120336838	1.33480909761992	0.813001011883961	0.348718238245645	0.241454842427671	0.396427698890539	0.533034509486969	NA	NA	0.517879352904662	0.591706190270391	79.6575802493348
a6349	loss_cnaOV42	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.47377417813569	1.18051250275815	0.293261675377536	0.798802961013443	1.28349912738825	0.235576444003815	0.36712642502661	0.228486073048047	0.53313947584672	NA	NA	0.266736138353068	0.553881507438127	79.6575802493348
a6350	loss_cnaOV44	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.35796104524169	4.50358171675258	-0.145620671510888	1.03057934187929	0.647425113582612	0.213893877303257	0.141299816126088	0.224922803357251	0.533166911865547	NA	NA	0.0533077102191228	0.831288966027251	79.6575802493348
a6351	PIK3R1_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.0677182094464252	0.639482146200643	-0.571763936754218	1.26863313964861	1.19914889440719	0.473894133941576	0.45069289054879	0.476808125680568	0.533188956778792	NA	NA	0.430696596210385	0.446529356795005	79.6575802493348
a6352	loss_cnaOV34	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	2.08498917008726	2.39014423462768	-0.305155064540427	2.13966104625361	1.45664146938154	0.195405486126878	0.142618413825279	0.209492226436468	0.533462060866252	NA	NA	0.241953564973809	0.772392583224624	79.6747745741247
a6353	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	3.74134932542721	3.24046490699779	0.500884418429413	1.60877125328269	0.852205001339532	0.515172679048048	0.31134595263768	0.587751089986684	0.533491129314411	NA	NA	0.18950659904742	0.647077307769823	79.6747745741247
a6354	loss_cnaOV33_(ZFHX3)	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.730127343532845	0.219192588917537	0.510934754615307	1.21082406100632	1.12668469512222	0.450123190434601	0.421972746553013	0.453485129271135	0.533576162783549	NA	NA	0.146637478961958	0.472475354135928	79.6747745741247
a6355	loss_cnaOV85	344	THZ-2-49	CDK9	7	25	2.99573227355399	NA	2.24137136730969	2.68407695859161	-0.442705591281915	2.17621880277269	2.38660200041281	0.188703733015802	0.203428805374657	0.18549619551368	0.533639933857155	NA	NA	0.385759675645888	0.651133687968467	79.6747745741247
a6356	loss_cnaOV70	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.67509476423517	3.95372747178064	-0.278632707545467	0.194659605356141	0.754697447127445	0.381251343504191	1.43138432360269	0.369197893282942	0.533806368291685	NA	NA	0.955768882847284	0.148836262705239	79.6852898806941
a6357	gain_cnaOV94	1170	CCT018159	HSP90	7	26	2.30258509299405	NA	4.06207616123896	3.59611992342374	0.465956237815227	1.2631305536451	1.20750322247136	0.382411545663695	0.368890006239327	0.385884053262872	0.533938006151667	NA	NA	0.197980623379019	0.404221565958222	79.6852898806941
a6358	gain_cnaOV49	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-3.30180990559683	-2.67325604123402	-0.628553864362813	1.46173305502633	1.79340611693395	0.354469183378361	0.430005918113065	0.35048049542588	0.533993609728481	NA	NA	0.696141854805849	0.543895905012118	79.6852898806941
a6359	loss_cnaOV33_(ZFHX3)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	0.81119726626092	1.3965442359113	-0.585346969650379	0.726541269660498	1.38679664479517	0.433059074239567	0.805662381606901	0.422085654625183	0.534169478072616	NA	NA	0.580676741627088	0.304958074433518	79.6852898806941
a6360	loss_cnaOV82	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.519152111183203	-0.0676118555552508	-0.451540255627953	1.33892807752553	1.25703402304881	0.357555844306407	0.337240112599957	0.359210846602852	0.534229838128281	NA	NA	0.767033187278389	0.62447401168747	79.6852898806941
a6361	loss_cnaOV55	256	JW-7-24-1	LCK	7	25	2.32630161961136	NA	1.67689788379416	2.01282917651491	-0.335931292720751	1.32419398231756	1.35061693497001	0.249693637268759	0.253687373003173	0.24872433035812	0.53435671760335	NA	NA	0.838981227279201	0.568124006712296	79.6852898806941
a6362	loss_cnaOV70	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	2.37879555657899	2.95979128009638	-0.580995723517392	0.0644265250826717	1.28939836343441	0.466367966283583	9.01795840722222	0.450594432251229	0.534415114398828	NA	NA	0.231404954874352	0.02312494207095	79.6852898806941
a6363	loss_cnaOV1	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.27877227557238	2.86904933143955	0.409722944132827	1.08793497870738	0.821244316596203	0.481882388794722	0.376606095172742	0.498905058887955	0.534662771021265	NA	NA	0.329620176390303	0.586581055767147	79.6852898806941
a6364	loss_cnaOV42	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	2.11379622195528	1.17219238868576	0.941603833269521	2.29747468553113	2.32728144016814	0.405109734233831	0.409842963319459	0.40459388238042	0.534708470356939	NA	NA	0.363278163324435	0.487312420290285	79.6852898806941
a6365	loss_cnaOV84	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	6	27	-1.38629436111989	0.693147180559945	-2.4736095012925	-2.25928683525855	-0.214322666033955	1.70110079649011	1.61177936321065	0.131767791858188	0.125990574148321	0.132972707633523	0.53474152799598	NA	NA	0.124185535357167	0.786103677178923	79.6852898806941
a6366	gain_cnaOV51_(MYC)	1133	JNJ-26854165	MDM2	8	25	2.30258509299405	NA	2.97720106175153	3.09686632628745	-0.119665264535922	1.00926013903933	0.898481875110643	0.12941582545559	0.118567314716131	0.133186064016245	0.534791980859387	NA	NA	0.238689787532836	0.770228015954788	79.6852898806941
a6367	loss_cnaOV52, loss_cnaOV53	1066	AZD6482	PI3Kbeta	9	24	1.6094379124341	NA	2.31385404291971	2.40358599704943	-0.0897319541297197	1.34669184698996	1.30652454054533	0.0681332099992632	0.0666313933141294	0.0686798841851575	0.534913561417428	NA	NA	0.109901267329092	0.866006272549245	79.6852898806941
a6368	loss_cnaOV20	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-2.2016710772635	-2.00383007813223	-0.197840999131277	1.38237540236491	1.59284576422301	0.125822640781131	0.143116695213774	0.1242059988324	0.535133172098089	NA	NA	0.0377681757055969	0.805709730818405	79.6852898806941
a6369	loss_cnaOV102	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.83167930012836	3.51465129744889	0.317028002679477	0.668937481923219	0.921222638976054	0.349692637092837	0.473927700639543	0.344138310617134	0.535161261804547	NA	NA	0.66314689609242	0.509975799509987	79.6852898806941
a6370	loss_cnaOV85	156	AZD6482	PI3Kbeta	6	13	1.63315443905142	NA	2.46213910723092	1.99024673662822	0.471892370602699	0.726380235412334	1.7794611461441	0.305219546095093	0.649649243739165	0.265188353016439	0.535178817424262	NA	NA	0.947671910964008	0.423841623605416	79.6852898806941
a6371	NF1_mut	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	2.61758675060992	2.98668191858255	-0.369095167972627	0.570725994802652	0.887950096966942	0.43427424513249	0.646711681847004	0.415671071193507	0.535230719972499	NA	NA	0.32963313333356	0.329733746459392	79.6852898806941
a6372	loss_cnaOV82	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	4.96794709270472	4.48874966775083	0.47919742495389	1.52996501877808	0.968196599004272	0.471946480566663	0.313208092389332	0.494938141124141	0.535266921360458	NA	NA	0.191179773821221	0.644469008646	79.6852898806941
a6373	loss_cnaOV34	1024	CEP-701	FLT3, JAK2, NTRK1, RET	5	26	0.693147180559945	NA	0.445263798648618	-0.273746850403065	0.719010649051683	1.90444415360275	1.54443368621609	0.449686086020369	0.377543572328696	0.465549706321985	0.535270786861594	NA	NA	0.100437517770207	0.462020405993437	79.6852898806941
a6374	loss_cnaOV42	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.790096153499	3.44509452408978	0.345001629409219	0.569366568750489	1.16373814352505	0.308860208148994	0.605939386582439	0.296459844793076	0.535306034724752	NA	NA	0.726689823240686	0.370429689211501	79.6852898806941
a6375	loss_cnaOV38	208	SB-715992	KIF11	8	24	-2.05572501506252	NA	-1.43201432625791	-1.27919396464141	-0.152820361616493	2.50767483234305	1.65105554246435	0.0810262448897337	0.0609410596802559	0.0925591887650217	0.53553647240926	NA	NA	0.0740210744533574	0.875515486836145	79.6948580638747
a6376	gain_cnaOV4_(KRAS)	308	XL-880	MET	8	24	1.63315443905142	NA	0.440301314506489	0.190697429442409	0.24960388506408	1.71719637117316	0.580381423351294	0.256589592360379	0.145355469679659	0.430068701411554	0.53569897178837	NA	NA	0.368108979297062	0.697768265884556	79.6948580638747
a6377	loss_cnaOV55	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	4.41944080390203	3.75183510238065	0.667605701521378	1.415274656577	1.77314474411656	0.391494301751919	0.471714587991038	0.376509421318564	0.535702443753298	NA	NA	0.147126048628573	0.321530229753737	79.6948580638747
a6378	TP53_mut	1494	SN-38	TOP1	22	10	-2.99573227355399	NA	-4.0944902581701	-4.379144424547	0.284654166376897	1.45726995654114	1.03039720489872	0.211871070080693	0.195333860482877	0.276256733833896	0.535748414169845	NA	NA	0.217557951088513	0.533145351133248	79.6948580638747
a6379	TP53_mut	151	QS11	ARFGAP	12	7	2.32630161961136	NA	3.66158171130228	3.94711850206653	-0.285536790764252	1.45144102065437	1.50692146347217	0.194076196465039	0.196726416506763	0.189483524978358	0.535790275568951	NA	NA	0.0644471361291535	0.693279431353725	79.6948580638747
a6380	loss_cnaOV21, loss_cnaOV22	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.29061885314836	1.49025471455535	0.800364138593018	0.489646187344643	1.66843331845545	0.495026642277613	1.63457647435876	0.479709994843518	0.536125697411415	NA	NA	0.0787175475075305	0.08950200759934	79.7322504159256
a6381	loss_cnaOV36	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.91154291755736	1.58374298686033	0.327799930697026	1.09923671960661	0.64217282919346	0.480477584227246	0.298206860133219	0.510454375823917	0.536379011487801	NA	NA	0.208898958863859	0.659160434942546	79.7331363115784
a6382	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.57479613610093	-2.3706004383811	0.795804302280174	1.94834072978463	1.58569693303909	0.493810597119156	0.408452325671056	0.501864060968425	0.536432356269854	NA	NA	0.124205028736781	0.556473254430621	79.7331363115784
a6383	loss_cnaOV35	1017	Olaparib	PARP1, PARP2	5	26	1.6094379124341	NA	3.84585968169744	3.99343984648683	-0.147580164789392	1.49835773822589	1.11574419288475	0.125499396803258	0.0984946124842872	0.132270609814087	0.53651087919906	NA	NA	0.0827474256118862	0.842608708495305	79.7331363115784
a6384	loss_cnaOV42	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	3.50131720160027	2.7502718372607	0.751045364339561	2.12348819372428	1.81773869603831	0.405841425927309	0.353684737480146	0.413175648390187	0.536513289248384	NA	NA	0.346157527910701	0.541059067312825	79.7331363115784
a6385	loss_cnaOV84	302	PI-103	PI3Ka, PRKDC (DNAPK)	6	26	2.32630161961136	NA	1.96306616291929	1.13454518436564	0.82852097855365	2.08625606718579	2.36700681277235	0.356725492177686	0.397132927057829	0.350028979250484	0.536551820114186	NA	NA	0.36330692938084	0.417090221950623	79.7331363115784
a6386	gain_cnaOV95_(MECOM)	211	TL-2-105	CRAF	9	23	2.32630161961136	1.63315443905142	4.30305357267509	4.45066615667888	-0.147612584003793	0.522881732375975	0.669231015183661	0.233004231924502	0.282305873133186	0.220570446758631	0.536711713741007	NA	NA	0.270974869755665	0.516574606364952	79.7367079944786
a6387	loss_cnaOV83	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	1.70246745174333	1.03707303503153	0.665394416711795	2.52610197178648	1.28428158731634	0.422151142740953	0.263407583756891	0.518106327524493	0.536818283385126	NA	NA	0.534209860363742	0.641419059553634	79.7367079944786
a6388	loss_cnaOV34	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.0490244578566	0.704419940091526	0.344604517765074	0.776385056046707	1.08448128584907	0.328618873136677	0.443857741826941	0.317759764287011	0.537025819801884	NA	NA	0.771853863900121	0.422107938491932	79.7367079944786
a6389	loss_cnaOV54	228	KIN001-102	AKT1	10	22	2.32630161961136	NA	2.73763378067761	2.81214497519874	-0.0745111945211279	1.41386997557929	1.15503250176266	0.0601684069857083	0.0527001745620909	0.0645100414121841	0.537046617921695	NA	NA	0.0946750875427675	0.88592219452922	79.7367079944786
a6390	gain_cnaOV49	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.00845480632017	4.30581805181512	-0.29736324549495	0.3634898077861	0.925245168341544	0.330850139290905	0.818078634188107	0.321388595876658	0.537072423878346	NA	NA	0.521407653326798	0.319331533707451	79.7367079944786
a6391	loss_cnaOV40	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	4.25493263157564	3.77706346521921	0.477869166356433	1.42804783298562	1.63057894272365	0.300396841698758	0.334631064393237	0.293067176225286	0.537088518807072	NA	NA	0.715504389053144	0.466899097005715	79.7367079944786
a6392	loss_cnaOV34	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.76599342082002	4.38418664777857	0.381806773041452	1.00093103177638	1.00903978415272	0.378777628157028	0.381451629453278	0.378386243077671	0.537164113775009	NA	NA	0.374777469930802	0.464749364942741	79.7367079944786
a6393	gain_cnaOV49	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	3.94737586471212	4.31989997891983	-0.37252411420771	1.26614514280166	0.774700950664176	0.455337906238331	0.294219123554356	0.480861826603328	0.537428400401082	NA	NA	0.316707243909398	0.66352858446813	79.7573350357863
a6394	loss_cnaOV52, loss_cnaOV53	1239	YK 4-279	RNA helicase A	6	18	2.30258509299405	NA	1.9130678932717	1.45498957065403	0.458078322617673	0.878268508483821	1.09171641963092	0.437501139755481	0.521569791234422	0.41959460751954	0.537471189795205	NA	NA	0.28677155729466	0.322294319007865	79.7573350357863
a6395	loss_cnaOV81_(RB1)	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	4.08918990120552	3.80719492910775	0.281994972097769	0.552711977237387	0.893614701032683	0.325439270860678	0.510202390596384	0.315566621466599	0.537675337098984	NA	NA	0.923721444619051	0.418379654835361	79.7579659882413
a6396	PTEN_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	3.28842025978067	2.56775676289894	0.720663496881739	0.993856765989187	1.75855748622143	0.424005048635475	0.725118066851879	0.409803775269361	0.53780367435057	NA	NA	0.639937680805687	0.270865541083359	79.7579659882413
a6397	loss_cnaOV20	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.02983794850676	4.42901131486102	-0.399173366354259	0.773025730562524	1.09827709792901	0.376334210688572	0.516377852084929	0.363454147507008	0.537926070760385	NA	NA	0.351670342093988	0.355710274213596	79.7579659882413
a6398	loss_cnaOV35	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.49088751997077	2.98207022935845	-0.491182709387685	1.33170821703932	1.2304748189338	0.394699103869708	0.368836583797383	0.399181439416445	0.538045683456236	NA	NA	0.231459362808104	0.475922033310705	79.7579659882413
a6399	PTEN_mut	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.35229265879852	5.81842259532817	-0.466129936529646	0.182683773709563	0.569141548586993	0.845576479491985	2.5515672632793	0.819005285568953	0.538066421389604	NA	NA	0.110553394642682	0.0154906612587396	79.7579659882413
a6400	gain_cnaOV26	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.28807985918675	1.4905173691031	0.797562490083646	2.88084799202115	1.48607657605504	0.493255541784151	0.276849904018744	0.536690035314914	0.53807613542848	NA	NA	0.07873570007521	0.680594882997632	79.7579659882413
a6401	loss_cnaOV16, loss_cnaOV17	291	KIN001-266	MAP3K8 (COT)	6	26	2.99573227355399	NA	3.5613335202906	3.2426968088543	0.318636711436299	0.665472462060861	1.17749998456378	0.287394927343182	0.478812767773338	0.270604429395677	0.538156927409284	NA	NA	0.950911076781062	0.387246771239992	79.7579659882413
a6402	loss_cnaOV41	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.35340121806801	4.89223188845308	0.461169329614929	1.66929949138293	1.15432702119302	0.373278879833921	0.276265183087592	0.399513587699178	0.538230653420964	NA	NA	0.372449207372074	0.580929971353515	79.7579659882413
a6403	KRAS_mut	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	3.16033353056966	2.6243419929763	0.535991537593361	0.942401281578225	1.37830069559665	0.401663456041472	0.568750858122503	0.388878522158284	0.538231975767641	NA	NA	0.941090093336847	0.453847501059936	79.7579659882413
a6404	PTEN_mut	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.26867434955611	2.46407742444915	-0.19540307489304	0.8303537724528	1.5232593717641	0.133040102220911	0.235325088384719	0.128279581609757	0.538425079312998	NA	NA	0.239985625064688	0.711434255331812	79.774122192374
a6405	gain_cnaOV4_(KRAS)	1069	EHT 1864	Rac GTPases	7	26	2.30258509299405	NA	4.43690520360054	4.17343734084375	0.26346786275679	0.878299029353691	1.00290448721084	0.268838029140871	0.29997512686615	0.262704839909049	0.538862191917884	NA	NA	0.209462988915247	0.509324140164685	79.806744531542
a6406	loss_cnaOV38	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.66261301628067	4.47516252241298	0.187450493867686	0.906438617106264	0.492701909022706	0.313057158070667	0.206798883377351	0.380454165967209	0.538874219253663	NA	NA	0.614953709503116	0.615204796867128	79.806744531542
a6407	gain_cnaOV19	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.91006811674838	1.58389555246126	0.326172564287114	0.0879037423594916	0.705865437010196	0.478042721635038	3.71056516516893	0.462088873013346	0.539003349190235	NA	NA	0.20893704413048	0.0277717127143682	79.806744531542
a6408	KRAS_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	7	24	-1.6094379124341	NA	0.75485529590743	0.510537654743794	0.244317641163636	0.532374298687188	1.3405077639083	0.20056951701101	0.45892080396464	0.182257535347142	0.539042215284672	NA	NA	0.430787666744885	0.478422617316566	79.806744531542
a6409	loss_cnaOV16, loss_cnaOV17	1008	Methotrexate	Dihydrofolate reductase (DHFR)	6	25	-1.6094379124341	NA	0.914780179970786	0.481928388215134	0.432851791755652	1.28420928741174	1.1937611219604	0.35777660926993	0.337057048254217	0.362594981351732	0.539065813318228	NA	NA	0.430788030244817	0.476187508779774	79.806744531542
a6410	NF1_mut	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	4.31106594910796	3.82184399221699	0.489221956890968	0.925281518689674	1.65510094784451	0.306690949038057	0.528727686665323	0.2955843615026	0.539179199037608	NA	NA	0.715523631193813	0.415456536194115	79.8110779083856
a6411	loss_cnaOV58	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.76457885140598	4.38443924945965	0.380139601946334	1.133067505087	0.988223765510281	0.377091425990029	0.335495987873332	0.384669560896509	0.539423685438745	NA	NA	0.37481111202857	0.512058139608688	79.8279697221312
a6412	ARID1A_mut	231	FMK	RSK	6	14	2.99573227355399	2.32630161961136	4.87393858474653	5.40096261400042	-0.527024029253893	0.724440335186071	0.701857719273906	0.744170952238157	0.727491283486483	0.750898671883406	0.53954396386053	NA	NA	0.126282269736605	0.165703371383722	79.8279697221312
a6413	NF1_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	2.19421027762959	2.7186822776784	-0.524472000048811	0.47914524544323	1.79009074189269	0.307106201970809	1.09459919520573	0.292986264760119	0.53958546197737	NA	NA	0.639956416589784	0.216473992403248	79.8279697221312
a6414	PIK3CA_mut	1022	AZD7762	CHEK1, CHEK2	7	24	0.693147180559945	NA	-0.97153560054606	-0.769905760002143	-0.201629840543917	0.91006608573961	0.780159807421582	0.249310231859212	0.221555163634136	0.258446844641101	0.539721831296455	NA	NA	0.0786820764807186	0.60801863449068	79.8279697221312
a6415	NF1_mut	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-4.4960531145882	-3.99513882786912	-0.500914286719072	1.4390518067315	1.53754701982731	0.327898082715575	0.348086347118239	0.325787946813706	0.539836669986636	NA	NA	0.864050759734723	0.554024833195174	79.8279697221312
a6416	loss_cnaOV44	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	3.08611018414072	2.20396145432074	0.882148729819973	1.92373611803238	1.77625270054596	0.493886849165716	0.458560153625563	0.496634701553911	0.540242530883176	NA	NA	0.110467818906341	0.514829724059936	79.8279697221312
a6417	gain_cnaOV19	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.90517938961165	3.3586831717976	0.546496217814054	1.63480236685944	1.18526147481282	0.447803274109385	0.334288858942568	0.461076504574957	0.540319567623522	NA	NA	0.326638065359414	0.624565394773927	79.8279697221312
a6418	PIK3R1_mut	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.47881269514638	3.02657612293021	0.452236572216171	0.919028007852367	0.958934426878858	0.473880509682734	0.492081382016835	0.471603229105156	0.540378286110344	NA	NA	0.670758453574597	0.496022787595999	79.8279697221312
a6419	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	286	KIN001-236	TIE2	7	25	2.32630161961136	NA	4.65332050860822	4.83476075166714	-0.181440243058922	0.892847966543048	0.594848280051573	0.272754261446762	0.203215160764074	0.305019362320743	0.540398419913546	NA	NA	0.76204102606595	0.626570786381641	79.8279697221312
a6420	loss_cnaOV85	167	OSU-03012	PDPK1 (PDK1)	6	13	2.77258872223978	NA	2.14480111684872	2.39069394188899	-0.245892825040267	0.868365293355634	1.36508433007103	0.19832891473019	0.283167495202464	0.180130135277044	0.540400053208197	NA	NA	0.388940026706508	0.642332911481309	79.8279697221312
a6421	gain_cnaOV49	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	0.535314971695172	0.874726702958471	-0.339411731263298	1.02048067684593	1.37273949824079	0.250898691202608	0.332599860991333	0.247251377044418	0.540479390878042	NA	NA	0.163220590703935	0.635392871507747	79.8279697221312
a6422	KRAS_mut	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.54504045054064	3.8423839074956	0.702656543045038	1.57366229501282	1.54633910546928	0.453450080570671	0.446510376001169	0.454400034610647	0.540536313826238	NA	NA	0.742950385566274	0.531777174153788	79.8279697221312
a6423	gain_cnaOV95_(MECOM)	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	2.85849575124819	2.32785272448122	0.530643026766964	1.70059989047324	1.55350310729847	0.334998604935926	0.312032847784847	0.341578349134909	0.540680175194622	NA	NA	0.227306724802125	0.554443766794862	79.8279697221312
a6424	loss_cnaOV34	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	3.15205340925634	3.61388927030657	-0.461835861050229	1.90986620158429	1.68109287150653	0.269376285680747	0.241815819698324	0.274723585399747	0.540718946365433	NA	NA	0.69846698788335	0.634363438536294	79.8279697221312
a6425	loss_cnaOV70	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.42801912411757	3.67966865420863	0.748350469908941	1.24799779138406	1.57650633599945	0.480511243478193	0.599640860805531	0.474689160976009	0.540820738136364	NA	NA	0.165091931641223	0.413427102283158	79.8279697221312
a6426	gain_cnaOV26	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.69138772726758	2.3627208475395	0.328666879728085	0.917017700149777	0.94718798683476	0.3477196216931	0.358408436036081	0.346992238390183	0.540906344621666	NA	NA	0.734748918764643	0.605354499935804	79.8279697221312
a6427	NF1_mut	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	-1.02409191002673	-1.35930007576251	0.335208165735774	2.26508841916879	1.83657939588582	0.177940498808977	0.147988998088995	0.182517655641071	0.541006245234105	NA	NA	0.0740699973096098	0.792756168005155	79.8279697221312
a6428	loss_cnaOV55	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	4.22144335373937	3.97983893184975	0.241604421889619	1.18890163873948	1.57584175834546	0.160382538434523	0.203216493288526	0.153317692344496	0.541086068920143	NA	NA	0.329640132041949	0.667263353553094	79.8279697221312
a6429	gain_cnaOV50	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	4.32666977145051	4.46940845879667	-0.142738687346164	0.667520944264894	1.02078205817755	0.14401492616598	0.21383402059894	0.139832676527448	0.5412069690947	NA	NA	0.0312665882966345	0.725590337840209	79.8279697221312
a6430	gain_cnaOV72_(ASXL1)	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	0.724504643840791	0.624169805363455	0.100334838477336	0.536193174104677	0.633259323159417	0.161519297999545	0.187124423291797	0.158441944410311	0.541306805324223	NA	NA	0.0150797658704428	0.721428194196165	79.8279697221312
a6431	loss_cnaOV35	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.04617928782209	0.704946823431251	0.341232464390838	0.773854691589555	1.08493244106681	0.32535513593671	0.440951599957249	0.314519551148553	0.54135416285977	NA	NA	0.771885115221219	0.425354464421774	79.8279697221312
a6432	loss_cnaOV52, loss_cnaOV53	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-3.12503334710386	-2.6123478950832	-0.512685452020662	0.746608974485741	1.33263811276458	0.420118462712061	0.686685359459811	0.384714685187179	0.541485808922958	NA	NA	0.378682108824515	0.312670330664907	79.8279697221312
a6433	gain_cnaOV48_(SOX17)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	0.629516883545635	1.2217095821333	-0.592192698587667	0.919276731636935	1.52632292545951	0.396216884034036	0.644194156348505	0.387986505810611	0.541499033290602	NA	NA	0.813042354532226	0.391164666620713	79.8279697221312
a6434	loss_cnaOV40	1054	PD-0332991	CDK4, CDK6	8	25	1.38629436111989	0.693147180559945	2.8179412974532	2.11334575209675	0.704595545356446	1.86327786964499	1.75249269401637	0.396260465880393	0.378148400104539	0.402053342511603	0.541598150270474	NA	NA	0.110482309436708	0.364867982807119	79.8279697221312
a6435	loss_cnaOV38	293	MP470	PDGFR	8	24	2.99573227355399	NA	4.32038095474492	3.95886331847457	0.361517636270355	2.11530321285262	1.65629167171161	0.203781081500526	0.170905822897525	0.218269307540961	0.54165367658763	NA	NA	0.622144379291019	0.668937074749186	79.8279697221312
a6436	SMARCA4_mut	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	3.12963250890194	3.26369843920547	-0.134065930303526	1.71519825191831	1.03675905337369	0.12241864267748	0.0781635185049801	0.129312524320155	0.541655076069737	NA	NA	0.0623326900274396	0.905664451290367	79.8279697221312
a6437	loss_cnaOV35	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.51159689635041	2.92366290043601	-0.412066004085593	1.31707437058924	1.08527898412487	0.368257110084072	0.312864644007339	0.379686707393368	0.541712773213268	NA	NA	0.390686436377432	0.538504089294661	79.8279697221312
a6438	gain_cnaOV4_(KRAS)	1072	BMS-708163	g-secretase	7	26	1.6094379124341	NA	4.02329118777372	3.79239900902042	0.230892178753304	0.810584790332249	0.879068086788306	0.266546535851196	0.284846423849951	0.262655626137986	0.541786635625545	NA	NA	0.923731271011051	0.525918147625957	79.8279697221312
a6439	loss_cnaOV39	155	AP-24534	ABL	5	14	-0.669430653942629	NA	0.430750117060046	0.916336813467442	-0.485586696407395	1.61766900693245	1.12028505362252	0.386867572274719	0.300176794094734	0.433449232262109	0.542046778049922	NA	NA	0.584035076886005	0.560193803442556	79.8279697221312
a6440	loss_cnaOV54	178	BAY 61-3606	SYK	6	13	2.07944154167984	NA	2.98205384015534	2.58293457218444	0.399119267970892	0.600728126980036	1.54216800245451	0.298739381737092	0.66439250976533	0.258804013139719	0.542242985580162	NA	NA	0.941104169963101	0.429527003561873	79.8279697221312
a6441	loss_cnaOV83	328	SNX-2112	HSP90	5	27	0.940007258491471	NA	1.29533316745779	0.585189048970311	0.710144118487477	2.02135759441053	2.35631970406827	0.306829194904051	0.351320380150039	0.301378508723323	0.542245272006225	NA	NA	0.945829708431485	0.50803556037255	79.8279697221312
a6442	PIK3CA_mut	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	2.86356551270345	2.93133034586989	-0.0677648331664353	1.45140583313282	0.774406378258083	0.0786043447099136	0.046689100745976	0.0875055204463355	0.542399176913185	NA	NA	0.329794543335442	0.943571793370497	79.8279697221312
a6443	loss_cnaOV81_(RB1)	341	EX-527	SIRT1	4	27	2.99573227355399	NA	5.99243386078858	5.74085093342333	0.251582927365254	0.314245891588395	0.584565417853281	0.447134169224298	0.800592574475983	0.430376001866737	0.542403695089204	NA	NA	0.110603114072307	0.236157764148295	79.8279697221312
a6444	loss_cnaOV55	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	2.7170084186089	2.37301853017189	0.343989888437006	0.406438565495921	0.916472246714755	0.405156453140956	0.846351497223898	0.37534130430037	0.542421290057369	NA	NA	0.621746426605463	0.29182827608718	79.8279697221312
a6445	gain_cnaOV95_(MECOM)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	8	25	0.693147180559945	NA	2.98400311215654	2.7383024330924	0.245700679064143	1.02807659476802	0.944371365515113	0.254900516912118	0.23899063582863	0.260173791832543	0.542493934716415	NA	NA	0.966188453686274	0.560718164696956	79.8279697221312
a6446	loss_cnaOV43_(NF1)	333	T0901317	LXR	5	27	2.32630161961136	NA	5.20362610947886	4.66996761102594	0.533658498452918	1.06287796191226	1.11814439010067	0.480369047671513	0.502088214805765	0.477271543082974	0.542511306630998	NA	NA	0.0051054346959763	0.347363300709125	79.8279697221312
a6447	loss_cnaOV40	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-4.64362975996308	-4.00127481306626	-0.64235494689682	0.879438611924361	2.61130566625865	0.273318975368075	0.730414764813701	0.245989948705298	0.542618853086997	NA	NA	0.928030982255178	0.322758782079917	79.8279697221312
a6448	gain_cnaOV51_(MYC)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	8	25	1.6094379124341	NA	2.76408345302226	2.20945267183333	0.554630781188924	1.58077602758037	1.53623000878671	0.358659104204248	0.350859812846399	0.361033685071001	0.542619112645373	NA	NA	0.242086784807437	0.4021929256298	79.8279697221312
a6449	loss_cnaOV16, loss_cnaOV17	1091	BMS-536924	IGF1R	6	26	1.38629436111989	NA	2.15599679916083	2.44834949867243	-0.292352699511596	1.20221351769237	0.88210875448859	0.310012375061437	0.243178682662596	0.33142477956824	0.542650549670732	NA	NA	0.734763276174564	0.593670251818038	79.8279697221312
a6450	gain_cnaOV94	205	BMS-708163	g-secretase	7	25	2.32630161961136	0.940007258491471	5.24960882570849	5.00947539656353	0.240133429144954	0.519201706920613	0.635691654991643	0.390992476055222	0.462505084140009	0.377751425961556	0.54272978775253	NA	NA	0.110521950432815	0.325398604104331	79.8279697221312
a6451	TP53_mut	163	JQ1	BRD4	12	7	0.940007258491471	NA	0.27774243649289	-0.235885456018596	0.513627892511487	1.86096008604625	1.89008808424464	0.274477634842981	0.276001563044121	0.271748124753009	0.542795895876291	NA	NA	0.581796525440034	0.575719691409404	79.8279697221312
a6452	loss_cnaOV21, loss_cnaOV22	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.6983250787796	1.26783280187301	-0.56950772309341	1.85541623531371	1.1828258163886	0.460282071830062	0.306943375968206	0.481480633245078	0.542902954368771	NA	NA	0.266880759959243	0.650687665369814	79.8279697221312
a6453	SMARCA4_mut	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	-0.10187247834463	0.778703020500732	-0.880575498845362	2.78876992544968	2.27695565555387	0.380443875485069	0.315757671799824	0.386733705901339	0.542911039223616	NA	NA	0.945830868760626	0.643780008409875	79.8279697221312
a6454	PIK3R1_mut	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.69567946544932	2.45401175782769	0.241667707621632	0.355794942005051	0.816937868011049	0.311017570636744	0.679233117423577	0.295821404643668	0.543248988827291	NA	NA	0.749177666090159	0.431677397183534	79.8554630948209
a6455	ARID1A_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	9	22	2.30258509299405	NA	4.50898342176859	4.51276172323371	-0.00377830146511737	0.548485514786821	1.03877995727047	0.00406391072985987	0.00688860756256412	0.003637249100421	0.543266346198709	NA	NA	0.528365317105924	0.989600640781713	79.8554630948209
a6456	loss_cnaOV85	186	Bexarotene	Retinioic acid X family agonist	5	13	2.07944154167984	NA	4.0336752770431	3.68201056433248	0.351664712710621	0.781470377339719	1.03739947134717	0.358949529663478	0.450003893823535	0.3389867861162	0.543574570706266	NA	NA	0.80784871028484	0.455658413999826	79.8729347457934
a6457	loss_cnaOV70	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	4.28635121101392	4.55925958654643	-0.272908375532515	0.76423916023563	1.03824389079969	0.266964576242571	0.357098130706063	0.26285574897273	0.543713910768869	NA	NA	0.191298312083094	0.612700725654388	79.8729347457934
a6458	loss_cnaOV20	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.54562978732285	2.32750350009156	0.218126287231286	0.383296452255444	0.926754105912646	0.249561046486617	0.569079849155291	0.235365870881662	0.543987859561465	NA	NA	0.607879254838548	0.392092379913336	79.8729347457934
a6459	loss_cnaOV82	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.13897878405689	4.83121061834352	0.307768165713367	0.619134226827668	0.618572053850907	0.497516028869061	0.497094414066422	0.497546185278437	0.544167118757676	NA	NA	0.0496317903963684	0.484934464392294	79.8729347457934
a6460	loss_cnaOV70	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	-0.184115322086502	0.415082738903245	-0.599198060989747	2.0203685500325	1.65181953012013	0.356700622977486	0.296578592544468	0.362750318702291	0.544190413234664	NA	NA	0.837193130654424	0.663229777586541	79.8729347457934
a6461	loss_cnaOV54	290	KIN001-260	IKK	9	22	2.99573227355399	NA	5.03087785361421	4.77635174429814	0.254526109316062	0.926844526786723	0.891885337991569	0.282284673045112	0.274615754811089	0.285379855990489	0.544709005342411	NA	NA	0.665329458047294	0.494092298534029	79.8729347457934
a6462	loss_cnaOV55	1007	Docetaxel	Microtubules	7	24	-4.38202663467388	NA	-4.75570781026207	-4.61732791158133	-0.138379898680731	0.95935299232029	1.53128764019959	0.0966458595582312	0.144242942679572	0.0903683247013567	0.544824719532851	NA	NA	0.135402144627069	0.776264624110931	79.8729347457934
a6463	loss_cnaOV39	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	8	23	2.32630161961136	NA	2.49067275062473	2.22535778089062	0.26531496973411	1.22668726534305	1.47366726040421	0.187105650162966	0.216285745544047	0.180037228798404	0.544898223515216	NA	NA	0.529887476722562	0.625094027266777	79.8729347457934
a6464	loss_cnaOV84	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	3.22483571170335	3.54986753238768	-0.325031820684331	1.11610376870846	1.11644151611055	0.291152694713599	0.291220072718196	0.29113197242671	0.545059543515203	NA	NA	0.772973753880202	0.593412493690334	79.8729347457934
a6465	gain_cnaOV50	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	3.79996550720665	4.00554242264217	-0.205576915435516	0.996960368996567	0.734253828221102	0.26886957839769	0.206203698590775	0.279980719928383	0.545448813296043	NA	NA	0.525550265910224	0.714281024792034	79.8729347457934
a6466	loss_cnaOV39	1049	PD-173074	FGFR1, FGFR3	10	23	0.693147180559945	NA	3.26449151242702	2.86564835412366	0.398843158303364	1.12763746055829	0.937674281000491	0.400219026940464	0.353698038823486	0.425353629063817	0.545623324049322	NA	NA	0.0876935996590635	0.342605149883845	79.8729347457934
a6467	loss_cnaOV54	266	Zibotentan, ZD4054	Endothelin A Receptor	10	22	2.99573227355399	NA	5.81810272817884	5.66824191088279	0.149860817296053	0.387044013193047	0.510115585214024	0.314474753517812	0.387193218827304	0.293778158597483	0.545691813842222	NA	NA	0.381694345982299	0.369647913934299	79.8729347457934
a6468	loss_cnaOV39	173	FH535	unknown 	5	13	3.46573590279973	NA	2.62347444620513	2.44811559619169	0.175358850013443	1.7166617873569	1.36113893055213	0.120259634779745	0.102151076761276	0.128832440302263	0.545887556118994	NA	NA	0.121086281752453	0.844313490912942	79.8729347457934
a6469	loss_cnaOV54	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	6	13	2.77258872223978	NA	4.75956840226071	5.15737592288334	-0.397807520622623	1.50352840029426	1.02453020505967	0.335512098623405	0.264582644760661	0.388282862387113	0.545971916699813	NA	NA	0.800734719006593	0.574339629717433	79.8729347457934
a6470	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1371	PLX4720 (rescreen)	BRAF	8	25	2.30258509299405	NA	4.72681838496758	4.46474290970544	0.262075475262141	1.09368572568824	0.956912455263319	0.264869661870461	0.239625944735835	0.273876125052656	0.546307918151306	NA	NA	0.325490193393695	0.556276826366685	79.8729347457934
a6471	gain_cnaOV95_(MECOM)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.09692315043753	3.8023632331763	0.294559917261228	1.02719268692896	0.860019498181846	0.332522313538035	0.286762085643235	0.342503766349429	0.546309521906402	NA	NA	0.939857206501651	0.621200778530397	79.8729347457934
a6472	loss_cnaOV34	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.680728664624533	0.209766111772046	0.470962552852486	1.05440614917749	1.14619438244612	0.415029811319875	0.446661424745929	0.410892393179764	0.54633935098834	NA	NA	0.146793820732097	0.400067359091036	79.8729347457934
a6473	gain_cnaOV94	226	GSK1070916	AURKB	7	25	0.940007258491471	2.32630161961136	2.58530698385431	2.2379954928252	0.347311491029108	0.829630020233728	1.56555399310962	0.239757644955748	0.418634189408023	0.221845744418723	0.546346536217048	NA	NA	0.820936093445795	0.442755403825873	79.8729347457934
a6474	gain_cnaOV51_(MYC)	1052	RO-3306	CDK1	8	25	1.6094379124341	NA	3.33173743727297	3.52980589163476	-0.198068454361788	0.800640074235236	0.937330169774341	0.21807352432516	0.247387634888225	0.211311297500935	0.546357736486686	NA	NA	0.794206908182812	0.569103479904133	79.8729347457934
a6475	loss_cnaOV35	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	4.11229652519561	3.62043458970399	0.491861935491619	1.65179656422603	1.1431264378053	0.402924334035523	0.297773918498303	0.43027780587067	0.54636258244251	NA	NA	0.198150780609529	0.552557981981229	79.8729347457934
a6476	loss_cnaOV85	1133	JNJ-26854165	MDM2	7	26	2.30258509299405	NA	2.96610178571233	3.09525208273893	-0.129150297026605	1.12437213544662	0.869809938321469	0.139687433894706	0.114864370038221	0.148481054695506	0.546380196368263	NA	NA	0.238856441179884	0.785044818357264	79.8729347457934
a6477	loss_cnaOV59	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	3.62651421670603	3.17301160548828	0.45350261121775	0.508349230444375	1.28694804915506	0.368269050481413	0.892108385452494	0.352386105651659	0.546408239971094	NA	NA	0.600911856515058	0.226176281089682	79.8729347457934
a6478	loss_cnaOV55	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	7	25	2.30258509299405	NA	1.13998040734357	0.793448878638071	0.346531528705504	1.06138777654837	1.29028700439439	0.27769826873126	0.326489089437627	0.268569339631652	0.546881980679314	NA	NA	0.844889567427057	0.482068380690834	79.8729347457934
a6479	loss_cnaOV1	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.07142723757851	1.33456030435863	-0.263133066780121	0.851900554044999	1.24775877350363	0.214740564350387	0.30887768006572	0.210884565484769	0.5469179083288	NA	NA	0.0975009730571404	0.661783127564994	79.8729347457934
a6480	loss_cnaOV70	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.3434790816204	3.71641452701038	-0.372935445389982	0.92471483583517	1.06445010328058	0.35325557951622	0.403297785368784	0.350355027671674	0.547116982587649	NA	NA	0.83098069679358	0.566014887861267	79.8729347457934
a6481	loss_cnaOV82	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.9784650714631	5.70040635028557	0.278058721177526	1.21544699605311	0.533714165767819	0.460657574759053	0.228770750251109	0.520988085031436	0.547311016189679	NA	NA	0.192344213346748	0.731364010868325	79.8729347457934
a6482	loss_cnaOV39	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	3.22631602268649	3.5493388498937	-0.323022827207207	1.25266250346574	1.07111140257525	0.289320356029714	0.257869000080627	0.301577246242147	0.547326583817708	NA	NA	0.773002958954489	0.625324449237974	79.8729347457934
a6483	loss_cnaOV38	1164	XMD8-92	MAP2K5 (ERK5)	7	16	2.30258509299405	NA	2.83197957159707	2.96209040339554	-0.130110831798472	0.854161528172278	0.862536921253184	0.151264881590839	0.152325792613115	0.150846680985474	0.547368944880269	NA	NA	0.329904162419013	0.743494323055077	79.8729347457934
a6484	loss_cnaOV36	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.68345951051894	3.95286215319956	-0.269402642680625	1.50243303558998	0.641505980059178	0.36846381970496	0.179310915228136	0.419953439336252	0.547382944124226	NA	NA	0.955788341851295	0.786457705203003	79.8729347457934
a6485	loss_cnaOV85	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	2.30258509299405	NA	1.86375622351297	2.25514463333814	-0.391388409825164	1.60502947001853	1.21074960629764	0.300569352168758	0.243851229610534	0.323261232371565	0.547389231980675	NA	NA	0.686527430173078	0.566507624958552	79.8729347457934
a6486	gain_cnaOV4_(KRAS)	1019	Bosutinib	SRC, ABL, TEC	5	26	0.693147180559945	NA	1.28540892527416	1.80774292988789	-0.522334004613735	2.12660783977791	1.49897929499551	0.326407498998985	0.245618395100191	0.348459786174232	0.547467015886526	NA	NA	0.0412231086100728	0.623122473660395	79.8729347457934
a6487	loss_cnaOV36	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.41174492689805	1.89047516616337	0.521269760734678	0.920078229016103	1.36912693423259	0.387888008534929	0.566549391449143	0.380731506846626	0.547523743945847	NA	NA	0.839048933953363	0.441076948225362	79.8729347457934
a6488	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.35883762002725	0.877269159075203	0.481568460952049	1.06568802321344	1.2865265885551	0.378584257230881	0.45188502682046	0.374316757411829	0.547571176711156	NA	NA	0.957472943850366	0.525691551178315	79.8729347457934
a6489	gain_cnaOV18_(CCNE1)	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.48016705457164	1.82043810346709	0.659728951104548	1.34881897931956	1.37561646235269	0.48048568204041	0.489116005349629	0.479587856906151	0.547597530775495	NA	NA	0.0342655600683001	0.413109715183785	79.8729347457934
a6490	loss_cnaOV54	231	FMK	RSK	6	14	2.99573227355399	2.32630161961136	5.20674881084633	5.25832965995765	-0.0515808491113159	0.798763336646711	0.733443078074043	0.0685772530843139	0.0645758846767523	0.0703269969453698	0.54763999834164	NA	NA	0.126441059663373	0.895204036694247	79.8729347457934
a6491	loss_cnaOV54	235	QL-XII-47	BTK, BMX	10	22	2.32630161961136	NA	1.51432764042639	1.58845303987664	-0.0741253994502495	1.54932619898816	1.66936491443892	0.0453566276837842	0.0478436364780119	0.0444033529212894	0.547643749735337	NA	NA	0.0788230586845037	0.90387861102112	79.8729347457934
a6492	PIK3R1_mut	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	1.51137718666096	1.57527249437946	-0.0638953077184952	2.44100860773151	1.47168830578717	0.039091918686371	0.0261757814028663	0.043416331751253	0.547690355125663	NA	NA	0.0788234774453204	0.957220743298195	79.8729347457934
a6493	loss_cnaOV39	1133	JNJ-26854165	MDM2	10	23	2.30258509299405	NA	3.28959445261012	2.9714487880477	0.318145664562418	1.10017654542242	0.825517900208707	0.348156053174683	0.289176919728155	0.385389177487229	0.547814483060053	NA	NA	0.238876617400484	0.426549272812172	79.8729347457934
a6494	loss_cnaOV83	1133	JNJ-26854165	MDM2	5	28	2.30258509299405	NA	3.37392798750833	3.01320095405917	0.360727033449161	0.999680196436633	0.903532529744147	0.39358954308264	0.360842432144775	0.399240781680886	0.547853826278953	NA	NA	0.238877169464606	0.483494414996737	79.8729347457934
a6495	gain_cnaOV72_(ASXL1)	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	1.59417460613451	1.93181706201774	-0.337642455883225	1.5171308725635	1.71489123911964	0.200776507640185	0.222553282639823	0.19688855373508	0.547956481287034	NA	NA	0.345854437058373	0.715723006046834	79.8729347457934
a6496	gain_cnaOV4_(KRAS)	170	Shikonin	unknown	6	12	2.77258872223978	NA	0.172451727100519	-0.103147414986248	0.275599142086767	0.633193523010427	0.853177720084684	0.348404566366889	0.435252623520959	0.323026651539156	0.547961741600111	NA	NA	0.584165624365854	0.453739754086307	79.8729347457934
a6497	PIK3R1_mut	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.15041692922835	4.55469563687137	-0.404278707643019	0.894196276015656	0.62016775111539	0.608198230435366	0.452114058721421	0.651886053274959	0.548086364551672	NA	NA	0.0534195985557036	0.379900739869535	79.8729347457934
a6498	loss_cnaOV82	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	2.88903997111028	1.95426808291468	0.934771888195603	4.29519814086501	1.70319380602775	0.47108715282105	0.217631843174375	0.54883471563093	0.548124939963542	NA	NA	0.132448635322026	0.743370723792602	79.8729347457934
a6499	gain_cnaOV95_(MECOM)	275	I-BET	BRD2, BRD3, BRD4	8	23	2.99573227355399	NA	3.68896440167926	4.00016818423505	-0.311203782555784	0.998827496601225	1.28696055930174	0.254326467500718	0.311569098382591	0.241812991320131	0.548283979231451	NA	NA	0.698760896891655	0.493136082315909	79.8729347457934
a6500	loss_cnaOV56	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	3.57928758942661	2.76810405108348	0.811183538343133	0.662585066772964	1.90907156804582	0.437943558780516	1.22427078275986	0.42490996771456	0.548284258424218	NA	NA	0.346337782099332	0.166634835761278	79.8729347457934
a6501	gain_cnaOV51_(MYC)	1371	PLX4720 (rescreen)	BRAF	8	25	2.30258509299405	NA	4.7807575778365	4.44748236798739	0.33327520984911	0.90060157870811	1.00860691233217	0.338263220855582	0.37005843397164	0.330431217329741	0.548340910092372	NA	NA	0.325519839069155	0.392501934987975	79.8729347457934
a6502	NF1_mut	346	THZ-2-102-1	CDK7	4	28	0.916290731874155	2.99573227355399	-0.396691993021267	-1.15409339385759	0.757401400836327	0.77397551377248	2.0633079060867	0.383947713563566	0.978585739934629	0.367081131517993	0.548487436383418	NA	NA	0.443599706356472	0.195550668987228	79.8729347457934
a6503	gain_cnaOV26	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	3.34126582930325	2.76758596316542	0.573679866137827	1.74321707739733	1.55053627470968	0.366877124566056	0.329092614784583	0.36998803284705	0.548496281037434	NA	NA	0.968812440703456	0.631328591618948	79.8729347457934
a6504	loss_cnaOV55	1033	Vismodegib	SMO	7	24	2.30258509299405	NA	5.1744178575987	4.83409658483351	0.34032127276519	0.882381565993735	0.847521950892098	0.39810599001655	0.385684930285144	0.401548623498152	0.548514685304997	NA	NA	0.154242868261017	0.387468576136695	79.8729347457934
a6505	loss_cnaOV54	326	GSK690693	AKT	10	22	2.32630161961136	NA	4.09806325188231	4.1764165563712	-0.0783533044888882	1.51495234514517	1.44958508895025	0.053319681614532	0.0517199796679942	0.0540522285212174	0.548544338615871	NA	NA	0.0935698921903784	0.892319466820892	79.8729347457934
a6506	loss_cnaOV55	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	2.30258509299405	NA	1.86458319602947	2.25490343302082	-0.390320236991351	2.15592528648849	0.962090019372689	0.299735250315093	0.181045344863084	0.40570032858864	0.548670063196694	NA	NA	0.686539857109722	0.656185637791969	79.8729347457934
a6507	loss_cnaOV54	287	KIN001-244	PDPK1 (PDK1)	10	22	2.99573227355399	NA	3.65867411354593	3.49241747231561	0.166256641230322	0.843183070395653	0.934568571605444	0.183078025263749	0.197177394883306	0.177896674766967	0.548691961296071	NA	NA	0.663284556447249	0.623094807648821	79.8729347457934
a6508	gain_cnaOV51_(MYC)	326	GSK690693	AKT	8	24	2.32630161961136	NA	4.05932472182285	4.18279995768361	-0.123475235860758	1.90467659005858	1.307821638713	0.0840572746482015	0.0648274024604671	0.0944129017335017	0.548764369224233	NA	NA	0.0935720618611124	0.868302610736925	79.8729347457934
a6509	gain_cnaOV96	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.4317960389786	5.14617033647284	0.285625702505753	0.514933739423128	0.802403326542805	0.370799119672307	0.554684380995766	0.355962759696405	0.548768482153053	NA	NA	0.333626941779278	0.33253369966474	79.8729347457934
a6510	loss_cnaOV52, loss_cnaOV53	330	XMD13-2	RIPK	8	24	2.32630161961136	NA	4.30829282063449	4.00926532315205	0.299027497482436	0.696170198208314	1.22201026923749	0.266611207351754	0.429532172236075	0.244701296715799	0.548843603402164	NA	NA	0.819639910839641	0.402777603044487	79.8729347457934
a6511	loss_cnaOV16, loss_cnaOV17	203	BMS-345541	IKBKB	6	26	2.77258872223978	NA	3.17228094692658	3.30017012136107	-0.127889174434497	1.13819446386402	1.02974260459609	0.121962161942524	0.112361444809994	0.124195283232611	0.549185398999241	NA	NA	0.0919433987638159	0.807951095936614	79.8729347457934
a6512	ARID1A_mut	1114	Cetuximab	EGFR	9	23	4.18661983833127	NA	5.8055860850473	5.82895788828719	-0.0233718032398942	1.26888767482704	1.30729915118284	0.0180175703135439	0.0184191270067147	0.017877930402347	0.54919107155293	NA	NA	0.570978385520494	0.963563498308809	79.8729347457934
a6513	loss_cnaOV38	1194	SB-505124	TGFR1 (ALK5)	8	24	2.30258509299405	NA	4.75611836876083	4.53254346771909	0.223574901041741	1.3186955019813	0.800298456954808	0.236090085283698	0.16954247641387	0.279364403490742	0.549276062760013	NA	NA	0.943144226245518	0.661833817105772	79.8729347457934
a6514	loss_cnaOV57_(ZNRF3)	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-4.09199585597866	-4.73103115281007	0.639035296831406	2.13395830152552	1.30786463522822	0.451342814628444	0.29946006741302	0.488609661595365	0.54939004047439	NA	NA	0.135458513276912	0.596974141642276	79.8729347457934
a6515	loss_cnaOV38	164	JQ12	HDAC	4	15	1.63315443905142	NA	1.10607685766778	1.97731071074488	-0.871233853077102	2.79641573141916	2.06592261275147	0.393790614439767	0.311553766233091	0.421716596594469	0.549391247835916	NA	NA	0.660389561696098	0.592290502211204	79.8729347457934
a6516	loss_cnaOV85	231	FMK	RSK	6	14	2.99573227355399	2.32630161961136	5.49411415000484	5.13517308603257	0.35894106397227	0.704701491154559	0.742674433352709	0.490139745875157	0.509351929118516	0.483308766065739	0.549405084797251	NA	NA	0.126475115388202	0.328596537064387	79.8729347457934
a6517	loss_cnaOV56	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-2.26105039692117	-2.00453375813788	-0.256516638783296	1.68679791557177	1.5630747557872	0.163186822379818	0.152073130050285	0.164110281887387	0.549495452252032	NA	NA	0.0378533979840514	0.821109032787136	79.8729347457934
a6518	loss_cnaOV54	303	PIK-93	PI4K, PI3K	10	22	2.99573227355399	NA	2.61363372212654	3.03790893505757	-0.424275212931031	1.23055543653207	1.24616391891467	0.341743485014898	0.344783502096189	0.340465011457358	0.549536652723779	NA	NA	0.231627232315611	0.379973098769868	79.8729347457934
a6519	TP53_mut	309	Y-39983	ROCK	22	10	2.99573227355399	NA	5.04708268273981	4.78214480582974	0.264937876910074	1.26312596585143	1.18789803652855	0.213481133890443	0.209747787689163	0.223030823154077	0.549542280455911	NA	NA	0.372620327986257	0.573396421824535	79.8729347457934
a6520	gain_cnaOV50	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.46381025782281	8.79191838452001	-0.328108126697206	1.01727760307427	1.26363427033975	0.264513703651248	0.322535486582664	0.259654343348086	0.549557242783003	NA	NA	0.529949828009127	0.588501126659486	79.8729347457934
a6521	loss_cnaOV41	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	1.04078648640478	0.705945490360382	0.334840996044398	0.78361874205334	1.0841770912758	0.319172911478068	0.427300902945486	0.308843452549227	0.549603195312538	NA	NA	0.771943406654379	0.437995179719919	79.8729347457934
a6522	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.49625775877593	4.26109120455585	0.235166554220084	0.645374703897034	0.834527399221981	0.285784929850538	0.364387622880247	0.281796085352412	0.549975106127358	NA	NA	0.316905644975716	0.604921033439396	79.8729347457934
a6523	gain_cnaOV4_(KRAS)	254	AC220	FLT3	8	24	0.0237165266173161	NA	2.62954263659209	2.4712450778137	0.15829755877839	0.508591801276841	0.663346406314764	0.251009819062276	0.3112467766507	0.238634832828621	0.549982096122817	NA	NA	0.858115516755764	0.492226814172767	79.8729347457934
a6524	loss_cnaOV57_(ZNRF3)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.72442928303989	4.48014413240368	0.244285150636207	1.41315768106881	0.851879757184716	0.263847090416644	0.172864750981962	0.286760130847009	0.550098618275079	NA	NA	0.528457442634032	0.756402888598271	79.8729347457934
a6525	SMAD4_mut	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.55988426880592	3.19755931405889	0.362324954747035	1.72238644279806	0.919950320160998	0.350354828171427	0.210362172938629	0.39385274053019	0.550149467898703	NA	NA	0.56553331998659	0.753196213554576	79.8729347457934
a6526	loss_cnaOV54	192	LFM-A13	BTK	6	13	2.77258872223978	NA	4.87109606333357	4.65769566324394	0.213400400089635	0.423797507880173	0.776910066632695	0.308374416798033	0.503543310476411	0.274678382035338	0.550222303259605	NA	NA	0.956913662012838	0.451059557308745	79.8729347457934
a6527	loss_cnaOV82	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	0.77115210150841	1.50412291319719	-0.732970811688776	0.41339906712723	1.8532499415017	0.409139021692293	1.7730345082351	0.395505644044345	0.550299462066775	NA	NA	0.614669876531887	0.104525666467925	79.8729347457934
a6528	gain_cnaOV96	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.63457516201947	2.24867507776985	0.385900084249621	2.03507302008153	1.13738253249801	0.306207458942088	0.189624686899029	0.3392878589423	0.550334851918109	NA	NA	0.844530671135363	0.733457462642226	79.8729347457934
a6529	gain_cnaOV95_(MECOM)	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-1.39432545051518	-2.4502714039113	1.05594595339612	2.51257537708238	2.69133339661184	0.39841640903039	0.420264388096602	0.392350481261616	0.550357790103395	NA	NA	0.416886918841881	0.45278654976952	79.8729347457934
a6530	loss_cnaOV54	1166	QL-VIII-58	MTOR, ATR	6	17	2.30258509299405	NA	-1.22499102099017	-1.16060524167471	-0.0643857793154632	0.654581143480178	1.49583718992192	0.0478999058365106	0.0983617996894115	0.0430433069516236	0.550445626918993	NA	NA	0.0492998630378215	0.887833990707856	79.8729347457934
a6531	gain_cnaOV4_(KRAS)	156	AZD6482	PI3Kbeta	6	13	1.63315443905142	NA	1.8190829399137	2.28704189077463	-0.467958950860934	2.19050380875532	1.17826025201388	0.30261890900438	0.213630740558646	0.39716094136342	0.550447364794431	NA	NA	0.947719103543989	0.639534030904132	79.8729347457934
a6532	gain_cnaOV96	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	0.51804435344602	0.802749589056448	-0.284705235610428	0.890622578327568	1.07374037994516	0.270846199895212	0.319669905679973	0.265152769634098	0.550544733996203	NA	NA	0.771949955774354	0.5478494535498	79.8729347457934
a6533	loss_cnaOV85	176	IPA-3	PAK1, PAK2, PAK3	6	13	3.46573590279973	NA	5.25509040803918	4.53248798896808	0.722602419071105	1.77858873766274	1.44587000722031	0.465848095395354	0.406278530707826	0.499769976182235	0.550628119682769	NA	NA	0.121642097161006	0.408459839163264	79.8729347457934
a6534	gain_cnaOV19	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.05166444985379	1.54385011187554	-0.492185662021746	0.335882975163993	1.77018492707146	0.287431408378415	1.46534864347155	0.278041946067184	0.550655811412568	NA	NA	0.316162585106367	0.212763921075395	79.8729347457934
a6535	ARID1A_mut	230	GSK429286A	ROCK2	8	24	2.99573227355399	2.32630161961136	5.19596129133686	5.65300730124981	-0.457046009912953	0.669178690355169	1.04108640876584	0.472552855880294	0.682995463693523	0.439008718262646	0.550698223409759	NA	NA	0.304232676951658	0.166873727781099	79.8729347457934
a6536	SMAD4_mut	263	FR-180204	ERK	3	29	2.99573227355399	NA	5.04683524927748	4.78744764879383	0.259387600483651	0.530827608456548	0.762573028184721	0.34614718544105	0.488647531423346	0.340147882100045	0.550789604569989	NA	NA	0.765232001297883	0.499362329615945	79.8729347457934
a6537	ARID1A_mut	1230	IOX2	EGLN1	9	23	-2.30258509299405	NA	0.172665679479288	-0.15572853327015	0.328394212749438	0.602420273338646	1.06096031329952	0.34195802888606	0.545124769671942	0.309525444668287	0.550897654344361	NA	NA	0.548982574223012	0.281960422767123	79.8729347457934
a6538	RB1_mut	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.530072630466	4.95175089813561	-0.421678267669606	1.06070294037314	0.84081086672593	0.491588290525276	0.397546053300526	0.501513817621788	0.550902132186456	NA	NA	0.154273783068565	0.566264025659675	79.8729347457934
a6539	PTEN_mut	1028	VX-702	p38	4	27	0.693147180559945	NA	2.94282103476711	3.38388006413334	-0.44105902936623	0.776105304891256	0.93623110296885	0.478913114135406	0.56829791857695	0.471100594679672	0.550967236573685	NA	NA	0.518128644372796	0.355783289159181	79.8729347457934
a6540	loss_cnaOV21, loss_cnaOV22	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	0.212256130169949	-0.0918804669106792	0.304136597080629	0.472004238591391	0.994050889496237	0.314175629683571	0.644351410886199	0.305956767701057	0.551096987341489	NA	NA	0.548985052877812	0.405516656850587	79.8729347457934
a6541	NF1_mut	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	0.560358793923454	0.981590191516093	-0.421231397592639	0.28918355920852	1.34261623376112	0.331110029961513	1.45662291018731	0.313739240596419	0.551119172392192	NA	NA	0.957478048820386	0.173594136251385	79.8729347457934
a6542	gain_cnaOV51_(MYC)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	8	25	0.693147180559945	NA	2.97750109059295	2.74038307999274	0.237118010600208	0.996338670829113	0.954789771110443	0.245889307524865	0.237989368015684	0.248345780165233	0.551131499442906	NA	NA	0.966197409924384	0.565520798044164	79.8729347457934
a6543	loss_cnaOV38	295	NVP-BHG712	EPHB4	8	24	2.32630161961136	NA	2.92812846029604	3.358796857554	-0.430668397257955	0.648971891261981	1.17894599509754	0.399199839570388	0.663616410905693	0.365299512487275	0.551166351174377	NA	NA	0.0624073014393786	0.208338130556613	79.8729347457934
a6544	gain_cnaOV50	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	4.70073896935493	4.97034223243348	-0.269603263078552	1.21012569126154	0.76713123613151	0.328575340491549	0.22278947139573	0.351443469357482	0.551188628934124	NA	NA	0.945983257037048	0.690995382385709	79.8729347457934
a6545	SMARCA4_mut	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.20673768812979	2.78447112825561	0.422266559874178	1.8158101398842	1.36839466052722	0.301044964419961	0.23254995145093	0.308585360682046	0.55121935166271	NA	NA	0.627490083496724	0.729587577150152	79.8729347457934
a6546	MLL2_mut	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	2.77066943641996	3.787388094281	-1.01671865786104	1.02373195644021	1.20782984267653	0.849525686111581	0.993149282353599	0.841773089169585	0.551431402256282	NA	NA	0.198218175347348	0.219403156606139	79.8729347457934
a6547	gain_cnaOV18_(CCNE1)	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.448982189351363	-0.854697888422134	0.405715699070771	0.90495914694819	0.795930590619624	0.504668809104377	0.448324877911863	0.509737537232896	0.551588477193995	NA	NA	0.0787930586933324	0.523200371952517	79.8729347457934
a6548	gain_cnaOV19	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.448982189351363	-0.854697888422134	0.405715699070771	0.90495914694819	0.795930590619624	0.504668809104377	0.448324877911863	0.509737537232896	0.551588477193995	NA	NA	0.0787930586933324	0.523200371952517	79.8729347457934
a6549	gain_cnaOV96	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	4.26609626788141	3.55775220142697	0.708344066454438	1.4223184648186	2.08617080473392	0.349010097829896	0.498020720376979	0.339542699402691	0.551646805824453	NA	NA	0.747437390396276	0.422974869090914	79.8729347457934
a6550	loss_cnaOV81_(RB1)	305	TPCA-1	IKK	4	28	2.99573227355399	NA	2.97509735728549	3.37520896202642	-0.400111604740926	0.731798427121195	1.27674653911751	0.324466510413928	0.546751113301672	0.313383739436242	0.551917174123851	NA	NA	0.993612426326745	0.396225154575301	79.8729347457934
a6551	ARID1A_mut	229	LY317615	PRKCB (PKCbeta)	8	24	2.99573227355399	2.32630161961136	2.64308915129052	2.78432863477104	-0.141239483480516	1.93224976266992	1.61266829060504	0.0834431657314616	0.0730958731159867	0.0875812368255382	0.551973277387903	NA	NA	0.321373889212158	0.85581167945347	79.8729347457934
a6552	loss_cnaOV38	196	Phenformin	AAPK1 (AMPK) agonist	8	23	8.29404964010203	NA	9.05659286254175	8.65347929556755	0.403113566974197	1.51791860045078	1.77159457904495	0.235215704595554	0.265569950097774	0.227542786449207	0.552131769512458	NA	NA	0.921805118311216	0.545895222639396	79.8729347457934
a6553	loss_cnaOV16, loss_cnaOV17	1241	CHIR-99021	GSK3B	6	26	2.30258509299405	NA	3.46677027313122	3.73099372651442	-0.264223453383204	0.738619766843785	1.10897600552295	0.250139047783344	0.357725944043258	0.238258945249772	0.552134325628236	NA	NA	0.831006953117774	0.492126626085862	79.8729347457934
a6554	KRAS_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.75589651383281	3.40966465440286	0.346231859429948	0.843752073473055	1.15033421171229	0.309512701096969	0.410347862026326	0.300983710564061	0.552190478121111	NA	NA	0.773064851775593	0.577231359650095	79.8729347457934
a6555	PTEN_mut	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	1.67029590289775	2.17669370655308	-0.506397803655322	0.727316169403854	0.51267409682007	0.942648950640924	0.696255390651347	0.987757733024395	0.552193593438669	NA	NA	0.0423518744111555	0.260181781584426	79.8729347457934
a6556	loss_cnaOV33_(ZFHX3)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.77645141556286	3.44711596674699	0.329335448815871	0.55154960199377	1.16533532188708	0.294685341719323	0.597109394377898	0.282610028744828	0.552526673453998	NA	NA	0.726839678784116	0.381669399834326	79.8729347457934
a6557	PIK3R1_mut	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	0.583074050932293	0.978095536591656	-0.395021485659363	1.18970714671508	1.28287640032852	0.310253880990771	0.332032539898632	0.307918584797574	0.552586832370553	NA	NA	0.957480142405402	0.572694891431767	79.8729347457934
a6558	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	8	25	-1.38629436111989	0.693147180559945	-1.97391076641451	-2.40204461713679	0.428133850722279	2.00232325815802	1.48691341114701	0.264653596282862	0.21381854751871	0.287934621823079	0.552591361809363	NA	NA	0.124385855479523	0.58989813953865	79.8729347457934
a6559	gain_cnaOV72_(ASXL1)	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-2.56499751937776	-2.26251095851794	-0.302486560859819	1.03864082138551	0.678794121591449	0.400715588905113	0.291233075603858	0.44562342430225	0.552763248720996	NA	NA	0.674346217214749	0.612554536204895	79.8729347457934
a6560	loss_cnaOV38	173	FH535	unknown 	4	14	3.46573590279973	NA	2.67006996972616	2.44732822161521	0.222741748110951	1.97857591147788	1.30774330260665	0.152851757162992	0.112576801738466	0.170325283002385	0.5527785043674	NA	NA	0.121232544071714	0.842823820971068	79.8729347457934
a6561	gain_cnaOV18_(CCNE1)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	4	27	2.32630161961136	NA	2.62718354207381	2.24443988137729	0.382743660696521	1.88999890115352	1.35166261358351	0.270133275751821	0.202509991123763	0.283165086353758	0.552794848097277	NA	NA	0.529992942860689	0.718936532586133	79.8729347457934
a6562	gain_cnaOV51_(MYC)	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	1.35183351684223	2.04248476932807	-0.690651252485846	1.09731096678259	1.79450577423272	0.41679218846566	0.629403399212254	0.384869896994981	0.552801664115849	NA	NA	0.345985457725217	0.334128270093521	79.8729347457934
a6563	gain_cnaOV18_(CCNE1)	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.56057141451692	2.96603232571809	0.594539088798828	0.478741126251897	1.22515692993971	0.500107695315593	1.24188012309183	0.485275864887026	0.552835523214806	NA	NA	0.0886081697226205	0.153899333790198	79.8729347457934
a6564	gain_cnaOV19	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.56057141451692	2.96603232571809	0.594539088798828	0.478741126251897	1.22515692993971	0.500107695315593	1.24188012309183	0.485275864887026	0.552835523214806	NA	NA	0.0886081697226205	0.153899333790198	79.8729347457934
a6565	loss_cnaOV70	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.3111396983001	2.7943165982734	-0.483176899973305	0.888904385115314	1.73056423255912	0.286316182718851	0.543564536370944	0.279201945170676	0.552900522250847	NA	NA	0.321387634610308	0.471397332808959	79.8729347457934
a6566	gain_cnaOV4_(KRAS)	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.22220891953303	2.85939304091453	0.362815878618497	0.402421142731165	0.90365736162486	0.42667256445688	0.90158254647389	0.401497175838993	0.552988053329992	NA	NA	0.330025893367453	0.235819714663222	79.8729347457934
a6567	BRCA1_mut	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.73413338587657	2.35829888285581	0.375834503020758	1.17028173360139	0.925299245674813	0.398293371822721	0.321148738999946	0.406176169252862	0.553072939200915	NA	NA	0.734847302583104	0.638144382067931	79.8729347457934
a6568	PIK3CA_mut	1248	FK866	NAMPT	7	25	0	NA	-2.40213000160935	-1.51410151857312	-0.888028483036235	2.13580163739133	2.88857315415817	0.322388852054387	0.415782284033115	0.307428074569584	0.553086242157544	NA	NA	0.0446098492351201	0.38743193021181	79.8729347457934
a6569	gain_cnaOV94	1018	ABT-888	PARP1, PARP2	7	24	1.6094379124341	NA	4.53167811570955	4.23189099328202	0.299787122427531	0.793682911151559	0.79866673902304	0.375843507172629	0.377716488808571	0.375359468198516	0.553169045611301	NA	NA	0.225184625863343	0.400836785203066	79.8729347457934
a6570	gain_cnaOV51_(MYC)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	8	25	-1.38629436111989	0.693147180559945	-1.83098339643414	-2.44778137553051	0.616797979096364	1.99518176556399	1.47290696152858	0.384116521627561	0.309143753086582	0.418762349019148	0.553478950627322	NA	NA	0.124395506589991	0.439339654101649	79.8729347457934
a6571	loss_cnaOV70	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.283909648284	4.87098264622654	0.412927002057464	0.35337715597243	0.884186597909999	0.481163066168276	1.16851639976886	0.4670134144009	0.553514455424644	NA	NA	0.154307326110154	0.173835971073977	79.8729347457934
a6572	PTEN_mut	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.30170807444942	1.61900604839706	-0.31729797394764	0.615139406801539	1.31709416858291	0.250411224186787	0.515814741242889	0.2409075839194	0.553520850855589	NA	NA	0.163990679688559	0.519922435454358	79.8729347457934
a6573	gain_cnaOV50	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	2.52909164929941	2.83493859059878	-0.30584694129937	1.00026462562917	0.960620208387711	0.317094938301522	0.305766027771891	0.3183848711789	0.553566196509266	NA	NA	0.966199886850937	0.596964097353638	79.8729347457934
a6574	loss_cnaOV57_(ZNRF3)	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	5.87952883415318	5.49006250800277	0.389466326150405	0.990284490892804	0.978355837795417	0.397595061787685	0.393287312617889	0.398082488093505	0.553591894393599	NA	NA	0.304275532683614	0.503199672446597	79.8729347457934
a6575	loss_cnaOV52, loss_cnaOV53	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	1.98843591114681	2.46307179476716	-0.474635883620354	1.41362423214251	1.81062084624176	0.274310169523799	0.335758168845896	0.262139853633928	0.553647045578843	NA	NA	0.643621761523254	0.667583360186297	79.8729347457934
a6576	loss_cnaOV54	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	1.98843591114681	2.46307179476716	-0.474635883620354	1.41362423214251	1.81062084624176	0.274310169523799	0.335758168845896	0.262139853633928	0.553647045578843	NA	NA	0.643621761523254	0.667583360186297	79.8729347457934
a6577	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	6	17	2.30258509299405	NA	4.04657945922057	3.7854774868692	0.261101972351376	0.851550371196217	0.895734808381439	0.294892287974141	0.306619527374045	0.291494725791865	0.553666299592996	NA	NA	0.939877478914359	0.539652242814679	79.8729347457934
a6578	NF1_mut	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.56963974129474	2.25314783161273	0.316491909682004	0.707460851047149	0.921399332242423	0.351023914414167	0.447363142728743	0.343490491697832	0.553963312215388	NA	NA	0.594474578716869	0.462574328833792	79.8729347457934
a6579	gain_cnaOV26	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.77184247090358	2.26660375154826	0.505238719355324	0.998173017719299	1.47509933052315	0.348873839707168	0.506163471048067	0.3425116593173	0.554054351289599	NA	NA	0.820978656863996	0.486394717963301	79.8729347457934
a6580	NF1_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	-0.722803676685995	-0.278740856357841	-0.444062820328154	1.87421572727461	1.35176626322737	0.314758015329923	0.236932608058886	0.328505624388011	0.554059223349205	NA	NA	0.88899395157941	0.674508024433967	79.8729347457934
a6581	ARID1A_mut	155	AP-24534	ABL	5	14	-0.669430653942629	NA	0.702338680620766	0.819340897910042	-0.117002217289276	1.12190483971947	1.31753012786069	0.0918236619929659	0.104288896122894	0.0888042063062767	0.55408129086652	NA	NA	0.584295599402922	0.853211383310069	79.8729347457934
a6582	gain_cnaOV95_(MECOM)	254	AC220	FLT3	9	23	0.0237165266173161	NA	2.61833655252481	2.46874756467575	0.149588987849062	0.463389494907382	0.681544821625463	0.237145152724166	0.32281480157197	0.219485179994907	0.55425270351729	NA	NA	0.858134208325254	0.483649991758717	79.8729347457934
a6583	loss_cnaOV52, loss_cnaOV53	1008	Methotrexate	Dihydrofolate reductase (DHFR)	8	23	-1.6094379124341	NA	0.857901448310844	0.46407300863984	0.393828439671004	1.01448038847561	1.26543802013267	0.325575341660114	0.388207050766927	0.311219066762127	0.554386924046301	NA	NA	0.431017967265456	0.390214796599672	79.8729347457934
a6584	loss_cnaOV82	152	CP466722	ATM	3	29	2.77258872223978	NA	2.41077497035252	2.67134513825399	-0.260570167901471	0.973427946248002	0.804497879198108	0.318994875230639	0.267683056466396	0.323891677826668	0.554544791026999	NA	NA	0.556003448122632	0.692948163169568	79.8729347457934
a6585	loss_cnaOV20	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.978972523707555	0.504481507050846	0.474491016656709	1.63010934316055	1.15355624107454	0.391630390108164	0.291079257135437	0.411328897336398	0.554640355929403	NA	NA	0.431021670542329	0.608688518583871	79.8729347457934
a6586	KRAS_mut	163	JQ1	BRD4	3	16	0.940007258491471	NA	0.848656088737884	-0.0540160762768215	0.902672165014706	2.14983813516203	1.81463927285721	0.486034802939214	0.41987912961953	0.497438900676617	0.554672840611349	NA	NA	0.582054089467585	0.551128602903977	79.8729347457934
a6587	loss_cnaOV70	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	3.48479929729979	3.83369690109944	-0.348897603799652	1.39536473265917	1.00362127372246	0.337306524939689	0.250040434327699	0.34763870887828	0.554812868649822	NA	NA	0.717252115262249	0.710471515636828	79.8729347457934
a6588	gain_cnaOV18_(CCNE1)	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	2.99412007288071	2.08594023411695	0.908179838763761	2.11762658063457	1.54311338089072	0.538094876884664	0.428866848890617	0.588537336277611	0.554849244378481	NA	NA	0.643667916456703	0.54863610879812	79.8729347457934
a6589	gain_cnaOV4_(KRAS)	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.47109689333345	2.24232800689119	0.228768886442251	0.846090617753072	0.917108590766909	0.253378628580489	0.270383433691515	0.249445800361491	0.554934939624555	NA	NA	0.59448600881004	0.550153125444344	79.8729347457934
a6590	loss_cnaOV43_(NF1)	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	1.23364676401328	0.77898477042461	0.454661993588673	1.43858374671938	2.17643521350008	0.217848039848933	0.316048331997013	0.208902149151272	0.555103893802614	NA	NA	0.416078605481465	0.57405796236045	79.8729347457934
a6591	gain_cnaOV94	1133	JNJ-26854165	MDM2	7	26	2.30258509299405	NA	3.32727783039828	2.9980123784004	0.32926545199787	1.04061163619763	0.883093117365627	0.359578760969167	0.316415308597737	0.372854736972822	0.555195157470175	NA	NA	0.238978905015243	0.46437802394455	79.8729347457934
a6592	loss_cnaOV35	306	TG101348	JAK2	5	27	2.32630161961136	NA	3.21358859537772	2.75192343729309	0.461665158084622	1.13619878537628	1.43374534207925	0.330294732250682	0.406324284118759	0.321999412681687	0.555198981090197	NA	NA	0.627532479666244	0.452307334705106	79.8729347457934
a6593	gain_cnaOV26	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.30939871509412	2.98121445938506	0.328184255709064	1.72733323703582	1.02533251249723	0.302101243728049	0.189994755309776	0.320075928256444	0.555351611558935	NA	NA	0.434642393495762	0.775290480089253	79.8729347457934
a6594	gain_cnaOV94	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.41567305997276	3.86664029322708	0.549032766745674	1.06341265924141	1.61336885317238	0.352221401083417	0.516293239481775	0.34030207392817	0.555421712869513	NA	NA	0.743164222976136	0.49637294982475	79.8729347457934
a6595	loss_cnaOV55	266	Zibotentan, ZD4054	Endothelin A Receptor	7	25	2.99573227355399	NA	5.83747530250682	5.68080088814648	0.156674414360348	0.37223330168763	0.500067404033504	0.32828735439027	0.420903808579239	0.313306592464586	0.555431599812403	NA	NA	0.381837843144097	0.380863521404669	79.8729347457934
a6596	loss_cnaOV38	1006	Cytarabine	DNA synthesis	8	23	0.693147180559945	NA	-0.306253585119546	-0.0435025916582725	-0.262750993461273	1.35529101058748	1.23461608096664	0.207741285240556	0.193870535116571	0.212819999279089	0.555521266630891	NA	NA	0.76719253165095	0.6382654526412	79.8729347457934
a6597	gain_cnaOV95_(MECOM)	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	2.29395628309372	1.44270901309518	0.851247269998535	1.32764215200811	2.54801317373347	0.367016094827541	0.641172223035396	0.334082758587643	0.555577241653634	NA	NA	0.613475215362369	0.362076024356527	79.8729347457934
a6598	loss_cnaOV55	294	MPS-1-IN-1	MPS1	7	24	2.99573227355399	NA	4.38527763639871	4.25426598121252	0.131011655186189	0.498639944871448	0.88959623811732	0.158981322698441	0.262737986664835	0.147270918617476	0.555600448357845	NA	NA	0.316991887991488	0.622654220042123	79.8729347457934
a6599	loss_cnaOV44	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.82992742312429	3.45314837482312	0.376779048301168	0.690469589610061	1.14277903156961	0.337168971981873	0.545685217670416	0.32970420168076	0.555749719432053	NA	NA	0.726866756117164	0.46142823563084	79.8729347457934
a6600	gain_cnaOV96	172	Embelin	XIAP	4	15	3.46573590279973	NA	3.3231034677681	3.03794947875	0.285153989018098	0.475607667807508	1.03729886558684	0.296324601009433	0.599557173526285	0.27490051177948	0.555928260522493	NA	NA	0.67103680608699	0.442098443946239	79.8729347457934
a6601	loss_cnaOV38	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-4.55227334617504	-3.83050919255204	-0.721764153622995	2.6839406176195	1.56908897697095	0.397391856072762	0.268919568817867	0.459989308583588	0.556015446454687	NA	NA	0.590548298368577	0.636885459408128	79.8729347457934
a6602	gain_cnaOV96	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.91723303263007	2.46497902564119	0.452254006988876	1.35884310981753	0.989686286364564	0.43672721755486	0.332822828273094	0.45696703411962	0.556059790313328	NA	NA	0.19580443407504	0.561541864030632	79.8729347457934
a6603	loss_cnaOV52, loss_cnaOV53	303	PIK-93	PI4K, PI3K	8	24	2.99573227355399	NA	2.58331908492488	3.01265754638054	-0.429338461455662	1.3834745726653	1.1973408505124	0.345330837571411	0.310333467588442	0.358576641957825	0.556142085717433	NA	NA	0.231720814579115	0.449334084937141	79.8729347457934
a6604	SMARCA4_mut	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	2.88169381921399	3.46456098942494	-0.582867170210953	1.25977836769015	1.21589256506738	0.478203903360101	0.462674376033032	0.479373907659886	0.556287028244014	NA	NA	0.326878162297576	0.512139478982421	79.8729347457934
a6605	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.5362691847545	1.83681885548562	0.699450329268881	1.41784585685978	1.37236291677655	0.508564399214589	0.493319020459678	0.509668631175035	0.556406091098562	NA	NA	0.0343098689202246	0.487323678507008	79.8729347457934
a6606	loss_cnaOV56	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.10257609007319	4.4269908120922	-0.324414722019013	1.46176232491578	0.804552928181011	0.37626142687048	0.221933974141592	0.403223592452111	0.556607061431812	NA	NA	0.869556053354563	0.73945052793871	79.8729347457934
a6607	TP53_mut	1371	PLX4720 (rescreen)	BRAF	23	10	2.30258509299405	NA	4.58479028978178	4.39829431573958	0.186495974042202	0.950675602810022	1.08730024717851	0.187946803806683	0.196172041746895	0.171522056144244	0.556723547092794	NA	NA	0.325639933726214	0.645059901886378	79.8729347457934
a6608	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.92395654517834	5.68990357951034	0.234052965667998	0.892450586473131	0.545036042980632	0.388124879650732	0.262258739268636	0.429426583218305	0.556763948993093	NA	NA	0.192471586377619	0.59732387563036	79.8729347457934
a6609	gain_cnaOV4_(KRAS)	201	Epothilone B	Microtubules	6	13	-3.44201937618241	NA	-4.97814051685842	-4.50453858867374	-0.473601928184683	1.10432679253242	2.36422228845456	0.228278342149495	0.428860307824852	0.200320388864225	0.556943193740387	NA	NA	0.349966580918308	0.55960164210435	79.8729347457934
a6610	loss_cnaOV83	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	1.23115959758564	0.779482203710139	0.451677393875501	1.54941816396816	2.16382630818612	0.216407990928472	0.291514198283779	0.208740134162677	0.557075871111077	NA	NA	0.416108658225381	0.59635769618237	79.8729347457934
a6611	loss_cnaOV84	1017	Olaparib	PARP1, PARP2	6	25	1.6094379124341	NA	4.36939604545679	3.87369432577616	0.495701719680625	1.13784622882799	1.16424738644206	0.427425481815998	0.435649130015757	0.425770094443149	0.55715532446726	NA	NA	0.0829454591761934	0.368982404948482	79.8729347457934
a6612	loss_cnaOV57_(ZNRF3)	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	4.33174285323894	3.66714295122952	0.664599902009424	1.63926336839335	1.54808603866577	0.426807237635508	0.4054259460826	0.429304241114542	0.557224788058447	NA	NA	0.165296438539846	0.489179670840269	79.8729347457934
a6613	loss_cnaOV58	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	9.16339707712249	8.67945312741443	0.483943949708056	1.82084619144617	1.69584243974982	0.282409226726902	0.265779697363506	0.285370821229978	0.557348848112562	NA	NA	0.921818145481535	0.604098103952856	79.8729347457934
a6614	ARID1A_mut	185	OSI-906	IGF1R	5	13	0.940007258491471	NA	2.58030003404024	2.06494223870531	0.515357795334924	1.00706969882933	1.38696132056812	0.39569297031414	0.511739948023461	0.37157330034541	0.557363060459724	NA	NA	0.686036753141604	0.404327354781022	79.8729347457934
a6615	gain_cnaOV19	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.116566895385267	-0.377480007575906	0.494046902961173	0.734881644285655	1.44614885083528	0.35010948595791	0.672280913263813	0.341629357638957	0.557381613694454	NA	NA	0.88900485671778	0.381403034616214	79.8729347457934
a6616	gain_cnaOV72_(ASXL1)	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.01358281265966	1.58736046409828	-0.573777651438618	1.28231922622191	1.76130964546567	0.33647994742	0.447453052021325	0.325767620086425	0.557475304515444	NA	NA	0.316263088956534	0.417010171985036	79.8729347457934
a6617	loss_cnaOV83	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	8.32794192762068	8.8401175792417	-0.512175651621019	1.8733688498213	1.68526541446025	0.299091222866838	0.273398189400809	0.303913939742873	0.557523366145646	NA	NA	0.921818577228763	0.592734606639904	79.8729347457934
a6618	gain_cnaOV72_(ASXL1)	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-4.97273485177456	-4.56912702312073	-0.403607828653832	1.34853437045701	2.20588506041237	0.194002874907651	0.299293690613944	0.182968657749729	0.557597509859667	NA	NA	0.349983854742531	0.659718598145151	79.8729347457934
a6619	PIK3CA_mut	1042	BIRB 0796	p38, JNK2	7	26	2.30258509299405	NA	4.56554449900569	4.35225542845945	0.21328907054624	0.398635604053197	0.940808762353316	0.247182389292922	0.535047718712493	0.226708210085888	0.557667123400565	NA	NA	0.869560111834717	0.379352246777558	79.8729347457934
a6620	loss_cnaOV40	1024	CEP-701	FLT3, JAK2, NTRK1, RET	7	24	0.693147180559945	NA	0.350844728795536	-0.30612550911689	0.656970237912426	1.32804315372867	1.66009745295916	0.411359455135238	0.494690429349292	0.39574197089536	0.557736580966363	NA	NA	0.100677549337344	0.299228691274629	79.8729347457934
a6621	loss_cnaOV34	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	0.66449124732859	0.87590320597131	-0.21141195864272	1.44532795179284	1.34025199014069	0.156107876017146	0.146272656237276	0.157740454927828	0.557773207783723	NA	NA	0.163435166433937	0.772313175471892	79.8729347457934
a6622	loss_cnaOV82	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.40412137063395	3.99426595381095	0.409855416823003	1.63141022382401	1.49545864945357	0.272346510429716	0.251227686842801	0.274066699853427	0.557837430055105	NA	NA	0.329891011264984	0.711349486424663	79.8729347457934
a6623	loss_cnaOV42	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.40284531156606	4.50232555401975	-0.0994802424536916	0.846239274314777	0.659723356110901	0.145996080858701	0.117555690775807	0.150790845181126	0.55798015875418	NA	NA	0.0534908066607729	0.834150990676098	79.8729347457934
a6624	PIK3CA_mut	1020	Lenalidomide	TNFA	7	24	1.6094379124341	NA	4.2047249437044	4.45685817908488	-0.252133235380481	0.667937278653475	0.795377220676457	0.327130897591278	0.37748040637703	0.316998310771391	0.557982833156094	NA	NA	0.0431497285198198	0.418059601544499	79.8729347457934
a6625	gain_cnaOV4_(KRAS)	301	PHA-793887	CDK-pan	8	24	2.32630161961136	NA	2.7106683218617	3.10956323240673	-0.398894910545029	1.93429826279849	1.52028636751605	0.245271012152647	0.206222028017498	0.262381429622875	0.558005722560703	NA	NA	0.663556321068496	0.606849370720019	79.8729347457934
a6626	KRAS_mut	286	KIN001-236	TIE2	7	25	2.32630161961136	NA	4.90666566659186	4.76382410743172	0.142841559160145	0.451730695293234	0.710616521648611	0.214178419408597	0.316209548406759	0.201010748847713	0.558023148052469	NA	NA	0.762168958579855	0.529713520338533	79.8729347457934
a6627	loss_cnaOV43_(NF1)	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.30489834895293	4.42845600047872	-0.123557651525788	0.52974747628218	0.650278087811308	0.194416874127994	0.23323877329804	0.190007404280922	0.558051855288053	NA	NA	0.27129239892854	0.659796886286921	79.8729347457934
a6628	gain_cnaOV51_(MYC)	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.48931093210508	4.28270082662692	0.206610105478151	0.624171943399824	0.575115765513918	0.35281624996263	0.331014727052227	0.35924959437258	0.558115686918303	NA	NA	0.254182728379473	0.452728835821928	79.8729347457934
a6629	PIK3R1_mut	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	0.796785233214448	1.86078592113327	-1.06400068791882	1.67731815186567	1.55690996173751	0.677796235916459	0.634346374142163	0.683405408191617	0.558220187678522	NA	NA	0.0412884211513157	0.301265325478717	79.8729347457934
a6630	gain_cnaOV19	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.51248978854203	1.18641633089677	0.326073457645258	1.02062385923258	1.25903096149697	0.261900447926193	0.319484455213927	0.258987640190802	0.558294214007353	NA	NA	0.267099242271165	0.64605427116985	79.8729347457934
a6631	gain_cnaOV51_(MYC)	186	Bexarotene	Retinioic acid X family agonist	5	13	2.07944154167984	NA	4.02529568628956	3.68523348385307	0.340062202436497	1.18703294307978	0.901385455421202	0.346779604597415	0.286480846567072	0.377266130034894	0.558335331270466	NA	NA	0.808019408756917	0.583747625703328	79.8729347457934
a6632	gain_cnaOV96	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	4.22587360955296	3.87452181528253	0.351351794270429	0.959441363733066	1.25276090938423	0.2866593636294	0.366204551472915	0.280461971345458	0.558404668756698	NA	NA	0.698853991901424	0.543676649648695	79.8729347457934
a6633	ARID1A_mut	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-2.18409211006776	-2.16821188264252	-0.0158802274252481	2.70411078797452	2.69290958645155	0.00589127682655192	0.00587262455956656	0.0058970518375901	0.558423427872966	NA	NA	0.417096254383053	0.991308708310247	79.8729347457934
a6634	loss_cnaOV58	341	EX-527	SIRT1	5	26	2.99573227355399	NA	5.96744851433317	5.73597954130455	0.231468973028619	0.526540452956844	0.568075119513089	0.411479506865352	0.439603399375642	0.407461909662611	0.55851154581278	NA	NA	0.110781570938018	0.408761441981014	79.8729347457934
a6635	TP53_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	23	10	0.693147180559945	NA	2.86368259570612	2.64648860233216	0.21719399337396	1.03538515351722	0.764146611706329	0.225181513769947	0.209771207010404	0.28423078771359	0.558537700190704	NA	NA	0.966204880666722	0.509336007750776	79.8729347457934
a6636	KRAS_mut	287	KIN001-244	PDPK1 (PDK1)	7	25	2.99573227355399	NA	3.75450231192001	3.48553637371851	0.268965938201507	1.00329447535372	0.877857639117843	0.297417495551895	0.268082746201389	0.306389015959114	0.558753705705128	NA	NA	0.663382865648779	0.53631541067473	79.8786498768997
a6637	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.28574534425355	1.87519584733941	0.410549496914136	0.693221549148479	1.41808068738818	0.305420703070138	0.592234181725072	0.289510674932246	0.558801020416422	NA	NA	0.839104541088863	0.340614691146016	79.8786498768997
a6638	PTEN_mut	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	1.49134500239544	2.50156449330627	-1.01021949091083	0.408326445479254	1.33275928475382	0.793583966679914	2.47404864929856	0.757990960908917	0.558830224727372	NA	NA	0.110151348671861	0.00668761019167235	79.8786498768997
a6639	loss_cnaOV81_(RB1)	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	0.933151675501569	0.295375560590237	0.637776114911332	1.45792194884323	1.69370412498738	0.379966323905822	0.437455595903035	0.376556982711538	0.559188247288989	NA	NA	0.837271014777256	0.536655570962639	79.9098205331624
a6640	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.03028422213308	4.33261176512408	-0.302327542991003	0.362471340736238	0.868971857787379	0.369605495893621	0.83407295698724	0.347914078323325	0.559241711415701	NA	NA	0.317046838089667	0.218365404704553	79.9098205331624
a6641	loss_cnaOV84	1192	GSK269962A	ROCK1, ROCK2	6	26	1.6094379124341	NA	2.88036033800984	2.33795012518237	0.542410212827467	1.41470780839526	1.46163548795816	0.373067594991776	0.383407944459385	0.371098141291841	0.559720352866224	NA	NA	0.240293789605583	0.425649903648279	79.9098205331624
a6642	loss_cnaOV87, loss_cnaOV88	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.75646253355234	4.36172440368968	0.394738129862669	1.20049451158021	0.726919885096235	0.513312916858606	0.328812940046745	0.543028383121492	0.559726231601914	NA	NA	0.0431604203467513	0.628908720157578	79.9098205331624
a6643	loss_cnaOV58	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	0.778097159384386	1.23747686848979	-0.459379709105401	2.09084202912373	1.38544018984387	0.30722040537974	0.219710385914677	0.331576716535969	0.559897524003344	NA	NA	0.813144495441751	0.657526681026186	79.9098205331624
a6644	gain_cnaOV18_(CCNE1)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	1.40662440417312	0.946685368834848	0.45993903533827	1.22697499938417	1.58631971197762	0.295946558139544	0.374856077401021	0.289940944354071	0.559929798494097	NA	NA	0.791084067984483	0.533086768727048	79.9098205331624
a6645	PTEN_mut	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	6.07834671549398	5.9291363321611	0.149210383332875	0.395457204893245	0.732026488649175	0.211197212049022	0.377311075602111	0.203831945491776	0.559951955739063	NA	NA	0.908731815310586	0.555686091931751	79.9098205331624
a6646	loss_cnaOV52, loss_cnaOV53	305	TPCA-1	IKK	8	24	2.99573227355399	NA	3.1035083505125	3.39909056507424	-0.29558221456174	0.800926058429375	1.33781968952733	0.239604660979285	0.369050565218692	0.220943238371811	0.559999553015052	NA	NA	0.993614015828451	0.460914814935254	79.9098205331624
a6647	loss_cnaOV52, loss_cnaOV53	1067	CCT007093	PPM1D	9	24	1.88706964903238	NA	4.68934680737053	4.41487094704313	0.274475860327395	0.320559527366668	0.783789742340369	0.395222399799893	0.856239908332031	0.350190676785103	0.560018594210906	NA	NA	0.0815651955771688	0.163806491839563	79.9098205331624
a6648	gain_cnaOV94	1036	PLX4720	BRAF	7	26	2.30258509299405	NA	4.64985894878995	4.21582218660197	0.434036762187983	1.2854338404184	1.31319079465229	0.331866777215854	0.337657799678517	0.330520716376869	0.560083170179791	NA	NA	0.371267736046868	0.448858860524873	79.9098205331624
a6649	loss_cnaOV83	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	1.96137386518959	1.45136351260273	0.510010352586857	1.13480911063664	2.01951649348342	0.264914189088768	0.449423914389209	0.252540820653141	0.560175580682	NA	NA	0.782682387916006	0.444317779353377	79.9098205331624
a6650	PIK3R1_mut	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	2.11052673234628	2.50823321437345	-0.397706482027173	1.05892836374791	0.815920741162023	0.468920802078636	0.375574491762174	0.487432739435898	0.560295207635562	NA	NA	0.622101690533285	0.589397865709464	79.9098205331624
a6651	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.66339723928005	3.92577950458045	-0.262382265300396	2.06059991599806	1.44953435428617	0.172805945971248	0.127332949624678	0.181011415510471	0.56045869852399	NA	NA	0.0697852800821119	0.848846991126141	79.9098205331624
a6652	loss_cnaOV35	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	3.56260049966655	4.11974349163284	-0.557142991966283	1.23662385817121	1.53136832882661	0.372563903652226	0.450535535348816	0.363820369977996	0.560626901195961	NA	NA	0.329931415282025	0.405601720527009	79.9098205331624
a6653	loss_cnaOV34	1129	PF-4708671	RPS6KB1 (p70S6KA)	5	27	2.30258509299405	NA	4.54614408187199	4.13238049765663	0.413763584215361	1.32257575823785	0.903015993276577	0.426778085216737	0.312846792811812	0.458201833960911	0.560813182551163	NA	NA	0.0482223045344481	0.533574066158164	79.9098205331624
a6654	gain_cnaOV50	306	TG101348	JAK2	4	28	2.32630161961136	NA	3.25668565400121	2.76225475599276	0.494430898008454	1.48348194898566	1.38846369125413	0.353605390662906	0.333290808389361	0.35609926361262	0.560947593504427	NA	NA	0.627592707997837	0.565591294292784	79.9098205331624
a6655	loss_cnaOV44	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.66794503331102	4.37045391776842	0.297491115542598	1.52869762278837	0.796916204463709	0.344693650583267	0.194604290023012	0.37330288162831	0.560972898385007	NA	NA	0.869572673458021	0.769609340261556	79.9098205331624
a6656	loss_cnaOV57_(ZNRF3)	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.96589025524025	2.36447515220856	0.601415103031691	1.88000788225503	1.4008129536967	0.413103066318797	0.319900309306314	0.429332910896187	0.561062642783834	NA	NA	0.240312478032146	0.575840829039165	79.9098205331624
a6657	KRAS_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	3.83679994560238	4.08753908612811	-0.250739140525725	1.50395457584249	1.50670314917381	0.166476447869938	0.166719889385798	0.166415753934818	0.561110562670243	NA	NA	0.329938381801109	0.705198031942396	79.9098205331624
a6658	loss_cnaOV20	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.29556867680211	-1.15252423827383	-0.143044438528283	1.42496893939111	1.32920208351657	0.106487246185071	0.100384250192433	0.107616772725665	0.561125125141988	NA	NA	0.0493990326766994	0.862181814026448	79.9098205331624
a6659	loss_cnaOV58	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.97767710868477	4.78104081553443	0.196636293150338	0.666679897555575	0.761779351037935	0.262252828719936	0.294948586077544	0.258127623021573	0.561181772248349	NA	NA	0.765304791832528	0.575174315436157	79.9098205331624
a6660	loss_cnaOV41	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.55340676841642	4.33205412598886	0.221352642427564	1.06768126914174	1.06802362519193	0.207263301052493	0.207320900745499	0.207254443821677	0.561214098951969	NA	NA	0.352018063033955	0.686150708146436	79.9098205331624
a6661	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.625223176041903	0.346289862979877	0.278933313062026	0.537071975241844	0.947719581898911	0.305233254639548	0.519359277565027	0.294320512511874	0.561233261407736	NA	NA	0.90969280949483	0.421910064312785	79.9098205331624
a6662	loss_cnaOV81_(RB1)	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	-0.411402825782532	0.196515050701722	-0.607917876484254	2.00931137289175	1.57272332653037	0.374485439201983	0.30255035863822	0.386538347991187	0.561239559721037	NA	NA	0.46206899381488	0.596942586603554	79.9098205331624
a6663	loss_cnaOV55	1026	17-AAG	HSP90	8	25	0	NA	0.172182062994284	-0.755796709101036	0.92797877209532	2.75303535782717	2.12079505725894	0.407197098450716	0.337074774378388	0.437561738424034	0.561251572772914	NA	NA	0.0613831515782271	0.403006484925223	79.9098205331624
a6664	gain_cnaOV48_(SOX17)	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.30616211550534	-2.106843216861	0.800681101355667	1.6995496602937	1.54346004044022	0.514997533440722	0.471113683855111	0.518757259907616	0.561303926894597	NA	NA	0.03792050633139	0.504744328983326	79.9098205331624
a6665	loss_cnaOV54	305	TPCA-1	IKK	10	22	2.99573227355399	NA	3.13761316731193	3.41045948603465	-0.272846318722719	0.716744704394139	1.39802222599539	0.221144467238998	0.380674341993716	0.195165937743553	0.561322217785474	NA	NA	0.993614271763027	0.471976591591247	79.9098205331624
a6666	loss_cnaOV52, loss_cnaOV53	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	0	NA	-2.48229050533427	-1.80511987113813	-0.677170634196137	2.46881112165333	1.84729734536026	0.334236329477017	0.274290174836317	0.366573706120968	0.561434628751017	NA	NA	0.278509292703016	0.469391109838854	79.9138332836256
a6667	loss_cnaOV1	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.951891724393285	-0.800814723953357	-0.151077000439928	1.05885527007355	0.790789162218783	0.186027424106957	0.142679556602136	0.191045866152287	0.561667317810553	NA	NA	0.0788839307115224	0.830449744983918	79.9198325105151
a6668	gain_cnaOV50	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.62488339951399	4.3661351391355	0.258748260378487	1.34632917432412	0.794158096918519	0.299764413772763	0.192187962136662	0.325814546728766	0.561764725969035	NA	NA	0.86957566116258	0.730201664168496	79.9198325105151
a6669	gain_cnaOV96	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.22628009717133	3.9446403383615	0.281639758809832	1.02030055851601	0.727387968167344	0.369720214729014	0.276036072370151	0.387193315170478	0.561879486987319	NA	NA	0.525759916446551	0.626454218764519	79.9198325105151
a6670	loss_cnaOV81_(RB1)	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-2.19638626848721	-2.80872535137958	0.612339082892369	2.00588636621702	1.74293183523858	0.345761847381349	0.305271072781258	0.351327040169962	0.561921541829976	NA	NA	0.696396313192931	0.595543700933559	79.9198325105151
a6671	gain_cnaOV49	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	1.69623820368776	1.9208219535923	-0.224583749904538	0.776762435257975	1.42185625621204	0.161651759515372	0.289127974925758	0.157951093103357	0.562320641148363	NA	NA	0.0343389039691161	0.689816124945245	79.9198325105151
a6672	loss_cnaOV70	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.22361201742519	3.57755480945266	-0.353942792027472	1.19383562657298	0.88113887124397	0.390945111935208	0.296475313811416	0.401687865078275	0.562322164719603	NA	NA	0.663416923539621	0.662305058308671	79.9198325105151
a6673	SMARCA4_mut	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	2.68274329372925	2.92834841073601	-0.24560511700676	2.08862331439235	1.17395371547237	0.195571718369475	0.117591867961225	0.209211925282705	0.562432951269491	NA	NA	0.231808010345781	0.858649886246475	79.9198325105151
a6674	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.75031371363596	4.38698659549001	0.363327118145949	1.14617072917717	0.986978075632055	0.36011080046408	0.316992145146456	0.368120758825647	0.562459267726872	NA	NA	0.375139708422354	0.534209810290005	79.9198325105151
a6675	RB1_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.141387750173988	-0.379962093054778	0.521349843228766	0.849789673023784	1.44089599165533	0.369684362160812	0.613504564457297	0.361823369797724	0.562512790303205	NA	NA	0.88902145585021	0.412416425954891	79.9198325105151
a6676	loss_cnaOV84	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	4.43595597135602	3.74033344181495	0.695622529541072	1.37545532751127	1.51720700243857	0.466470712603612	0.505739819845492	0.458488873583509	0.562631222078551	NA	NA	0.0698099622744915	0.360933272865502	79.9198325105151
a6677	loss_cnaOV85	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	4.43595597135602	3.74033344181495	0.695622529541072	1.37545532751127	1.51720700243857	0.466470712603612	0.505739819845492	0.458488873583509	0.562631222078551	NA	NA	0.0698099622744915	0.360933272865502	79.9198325105151
a6678	loss_cnaOV38	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-0.938679478202246	-0.453159184557362	-0.485520293644884	1.8127798136006	1.41566647903617	0.325102393041805	0.267831917589886	0.342962343768599	0.562669699885959	NA	NA	0.909266549196894	0.645204158571933	79.9198325105151
a6679	loss_cnaOV58	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.624203450903953	0.346440933370685	0.277762517533268	0.538038631524664	0.947702393107488	0.303937819109751	0.516250137552689	0.293090446487629	0.562832955992127	NA	NA	0.909697304441941	0.424360137698901	79.9198325105151
a6680	loss_cnaOV81_(RB1)	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	3.46699890280688	2.75517445137405	0.711824451432834	1.73468420290719	1.86501641736367	0.384272311551586	0.410348148809952	0.38167194926844	0.562965233954604	NA	NA	0.346552707661766	0.488823223737913	79.9198325105151
a6681	loss_cnaOV58	308	XL-880	MET	5	27	1.63315443905142	NA	0.425047847614669	0.221255910540606	0.203791937074063	0.426921908505982	1.03511941228271	0.208766521282226	0.477351789668596	0.196877707688477	0.562992879346192	NA	NA	0.368515003768515	0.471752190072891	79.9198325105151
a6682	gain_cnaOV95_(MECOM)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	1.6094379124341	NA	1.57041464021187	1.25971796880888	0.310696671402989	1.40478869508098	1.34034750856685	0.229096478572897	0.221169683733167	0.23180307302186	0.563009582709101	NA	NA	0.581031871804494	0.595821782678515	79.9198325105151
a6683	loss_cnaOV16, loss_cnaOV17	157	JNK-9L	JNK	3	16	1.63315443905142	NA	0.167630541690481	-0.0688364360951718	0.236466977785653	1.71465451931041	0.882880604442091	0.232584753299806	0.137909401061593	0.267835737466541	0.563070426856706	NA	NA	0.190850107837762	0.835548057186519	79.9198325105151
a6684	loss_cnaOV54	226	GSK1070916	AURKB	10	22	0.940007258491471	2.32630161961136	2.50972886145874	2.22498852695558	0.284740334503155	0.911665659875679	1.62678173900023	0.196403779120786	0.312329779474181	0.175032905568603	0.563074596363436	NA	NA	0.821027056808991	0.532862031798554	79.9198325105151
a6685	loss_cnaOV36	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.7163444998715	3.23065777025286	0.485686729618639	1.10429798689363	1.03485910630118	0.467171478172421	0.439814918964821	0.46932642971524	0.563077145168399	NA	NA	0.0920757278764796	0.530891871283222	79.9198325105151
a6686	gain_cnaOV18_(CCNE1)	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	2.71781515951301	2.43199772556926	0.28581743394375	0.478839265969493	0.822266154164422	0.369831520333467	0.596896399807697	0.347597225662529	0.56324098977943	NA	NA	0.749453454837045	0.396469024781259	79.9266115892131
a6687	loss_cnaOV55	193	GW-2580	CSF1R (cFMS)	7	25	2.99573227355399	NA	5.89425876867028	5.67949471967915	0.214764048991132	0.222842979031241	0.664280869639949	0.356483918673652	0.963746086705398	0.323303076765612	0.563462997349078	NA	NA	0.192559415388835	0.182791793271516	79.9266115892131
a6688	loss_cnaOV39	1218	JQ1	BRD2, BRD3, BRD4	9	22	0	NA	2.39925236815621	2.25092177751441	0.148330590641802	0.959325919120325	0.884277710596666	0.163792238793911	0.154619600789914	0.167742089237685	0.563521212723289	NA	NA	0.594585376442212	0.695540768988431	79.9266115892131
a6689	loss_cnaOV16, loss_cnaOV17	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	6	27	1.6094379124341	NA	2.80655023380531	2.24109937100665	0.565450862798664	2.13071159906434	1.41049776103912	0.364931334979514	0.265381228997378	0.400887458610422	0.563523393226861	NA	NA	0.242375859618699	0.557686734083243	79.9266115892131
a6690	loss_cnaOV59	333	T0901317	LXR	4	28	2.32630161961136	NA	5.2243864127669	4.68606108550097	0.538325327265929	0.939115034268807	1.13147936669687	0.483349595863418	0.573226183824293	0.47577122757215	0.563550344507368	NA	NA	0.00513084028896128	0.351228445261285	79.9266115892131
a6691	gain_cnaOV48_(SOX17)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	1.98685576898789	2.37961390376826	-0.392758134780366	1.85298282088724	1.53924042589516	0.251544632715245	0.211959943909413	0.255163604186107	0.563630329838775	NA	NA	0.242377286232819	0.752676888404612	79.9266115892131
a6692	PTEN_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	1.55815607206629	1.56388663749973	-0.0057305654334423	0.834026502691549	1.10769420936173	0.00528352763468236	0.00687096323072321	0.00517341824576687	0.563902789565311	NA	NA	0.454420333014417	0.992186454541014	79.942197299409
a6693	loss_cnaOV55	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	4.32327555519496	3.85467744338478	0.468598111810181	0.866190285752633	1.67168271127415	0.300372586969396	0.540987493761854	0.280315222888809	0.563958005833826	NA	NA	0.743281978808316	0.461447289367038	79.942197299409
a6694	loss_cnaOV40	333	T0901317	LXR	7	25	2.32630161961136	NA	5.14522244190083	4.64362795807156	0.501594483829273	0.918361906783746	1.15091391137763	0.452574334887707	0.546183895612503	0.435822765604482	0.564036228429869	NA	NA	0.00513140692622605	0.251941845960774	79.942197299409
a6695	SMARCA4_mut	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.03112130753097	2.82328401800814	-0.792162710477171	2.40864466576019	1.6120271165758	0.472383081644993	0.328883177223303	0.491407807183696	0.56407725194222	NA	NA	0.321549944116868	0.629304093415341	79.942197299409
a6696	loss_cnaOV33_(ZFHX3)	1028	VX-702	p38	4	27	0.693147180559945	NA	3.12378936537077	3.35706994108094	-0.233280575710171	1.59211542391247	0.819953231460526	0.250825326792256	0.14652240170936	0.28450473363541	0.564334818341998	NA	NA	0.518304774309552	0.791184219064972	79.9450952157093
a6697	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.48881516158214	-4.07501786176465	0.586202700182509	2.45752761860654	1.7277586344494	0.320541022588713	0.238533514636509	0.339285064762139	0.564479770471022	NA	NA	0.590722000613034	0.72527337312515	79.9450952157093
a6698	loss_cnaOV85	1022	AZD7762	CHEK1, CHEK2	7	24	0.693147180559945	NA	-0.556964722170019	-0.890822266195155	0.333857544025135	0.862722492193625	0.783492495529796	0.417046403326088	0.386981383986226	0.426114539615828	0.56448578549535	NA	NA	0.0789087985875322	0.381696790216656	79.9450952157093
a6699	loss_cnaOV84	155	AP-24534	ABL	5	14	-0.669430653942629	NA	1.01679020864167	0.70703678075972	0.309753427881946	1.55817569199316	1.16310243801933	0.244440998285819	0.198792363065119	0.266316549391325	0.564511529668355	NA	NA	0.584512819699147	0.699622081091866	79.9450952157093
a6700	loss_cnaOV81_(RB1)	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.67612572847042	2.48720428737085	0.188921441099565	0.494632295852267	0.644715257051499	0.299250876644108	0.381943198379409	0.29303082102255	0.564518982647665	NA	NA	0.858178034324395	0.526158180752743	79.9450952157093
a6701	loss_cnaOV82	1032	Afatinib	ERBB2, EGFR	3	28	-0.693147180559945	NA	-0.155487833884094	0.412015508024415	-0.56750334190851	2.06788344866415	1.64858416197022	0.33762622536165	0.274436812323788	0.344236803312661	0.564757219370423	NA	NA	0.83729892683969	0.685737792483033	79.9668980633595
a6702	loss_cnaOV84	266	Zibotentan, ZD4054	Endothelin A Receptor	6	26	2.99573227355399	NA	5.64234294320101	5.73185737161552	-0.0895144284145193	0.704494607450576	0.42173823530906	0.186271018070438	0.127061907171233	0.21225115704513	0.565167260504421	NA	NA	0.381976588294225	0.775188279682989	79.9793256931384
a6703	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1527	GDC0941 (rescreen)	PI3K	6	25	1.38629436111989	NA	0.580864157417062	0.334621362404877	0.246242795012185	0.48853768182961	0.978990484886328	0.26958479278818	0.504040536013491	0.251527260799452	0.565213523659364	NA	NA	0.909703947801153	0.391214765342612	79.9793256931384
a6704	gain_cnaOV49	152	CP466722	ATM	3	29	2.77258872223978	NA	2.41795257054562	2.67060262788919	-0.252650057343562	0.364291461244567	0.840128177255547	0.309213584336262	0.693538235786278	0.300727989113395	0.565223997782425	NA	NA	0.556130835409377	0.381578224355538	79.9793256931384
a6705	KRAS_mut	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	3.80158208736944	4.02975901004885	-0.228176922679415	0.288512427897229	0.839196429804975	0.299598476919755	0.790873808599654	0.27189930101638	0.56550218564269	NA	NA	0.525804573165552	0.263825758782429	79.9793256931384
a6706	RB1_mut	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.75342390556448	1.60010012603201	0.153323779532469	0.489281284211405	0.699818374139949	0.222922208814141	0.313365306379106	0.219090817272265	0.565505368160677	NA	NA	0.209303294984969	0.65656706660636	79.9793256931384
a6707	loss_cnaOV39	283	GSK2126458	PI3K, MTOR	9	23	-2.05572501506252	0.0237165266173161	-2.39778305851976	-2.86303510373474	0.465252045214987	1.63625027616397	1.81640582669975	0.262830798051851	0.284340392171377	0.25613882006771	0.565571478724022	NA	NA	0.696427802126232	0.493456525171727	79.9793256931384
a6708	loss_cnaOV33_(ZFHX3)	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.61420682546301	5.72948292926277	-0.115276103799767	0.575985278521182	0.468465467498427	0.240007650062037	0.200137239784554	0.246071720964478	0.565574477092768	NA	NA	0.381982291491657	0.723568653924304	79.9793256931384
a6709	gain_cnaOV18_(CCNE1)	302	PI-103	PI3Ka, PRKDC (DNAPK)	4	28	2.32630161961136	NA	2.06343154286038	1.17938734284217	0.884044200018206	2.34312037354275	2.32515052156217	0.379914813282533	0.377293548381191	0.380209449590496	0.565594581503672	NA	NA	0.363737117774762	0.519830554607826	79.9793256931384
a6710	loss_cnaOV84	1241	CHIR-99021	GSK3B	6	26	2.30258509299405	NA	3.92348868768951	3.62559716930866	0.297891518380842	0.85305874008137	1.09073705903403	0.282401891982384	0.34920399309481	0.273110293552012	0.565603621877358	NA	NA	0.831075240399454	0.484185136425497	79.9793256931384
a6711	PIK3R1_mut	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	4.56019643099264	4.52876294399722	0.0314334869954145	0.603617442442365	1.07581165791677	0.0306520843285491	0.0520751800481906	0.0292183922381759	0.565700055525586	NA	NA	0.191591447911714	0.928286183244629	79.9810422395543
a6712	loss_cnaOV52, loss_cnaOV53	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	3.23829719490761	3.54505985981473	-0.30676266490712	0.695679682011048	1.21823124084338	0.274512436951091	0.440953894212263	0.251809881919255	0.565828416330894	NA	NA	0.773232941781989	0.507864427770594	79.9872715970941
a6713	gain_cnaOV95_(MECOM)	1054	PD-0332991	CDK4, CDK6	8	25	1.38629436111989	0.693147180559945	2.63322299320271	2.17245560945691	0.460767383745806	2.19714977502461	1.65758367478671	0.256885951087974	0.209711412932987	0.277975338895092	0.565945051045786	NA	NA	0.110731646990485	0.597710583890228	79.9918417089015
a6714	loss_cnaOV36	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.5418130982081	2.12658305250292	0.415230045705185	0.99139964234639	1.32734737770655	0.317708261139867	0.418832152009296	0.312826960507232	0.566175267718153	NA	NA	0.686704331262113	0.556459941556462	80.003983048465
a6715	gain_cnaOV96	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	6.96885056564434	6.62531941956602	0.343531146078318	1.8352945904983	1.45392752145456	0.224800647117956	0.187180383932285	0.23627804069259	0.56619958870028	NA	NA	0.337436011357259	0.746174465463269	80.003983048465
a6716	gain_cnaOV26	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.75658929224634	2.44259116530325	0.313998126943098	0.396342370368667	0.810279013922543	0.406117949006758	0.79223961508588	0.387518523308459	0.566349415678416	NA	NA	0.749494647113544	0.344596867212501	80.0132379978746
a6717	gain_cnaOV4_(KRAS)	200	LAQ824	HDAC	6	13	0.0237165266173161	NA	-2.45350743919102	-2.88284558704139	0.429338147850369	1.36204838545581	1.16377583535988	0.350358292957331	0.315215048477658	0.368918252815931	0.56643908908091	NA	NA	0.379343494750417	0.521929177259274	80.0139930241695
a6718	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	134	Etoposide	TOP2	3	16	2.77258872223978	NA	2.72706518950559	2.20010684413546	0.526958345370128	3.72981780494598	1.411271641694	0.286034801136914	0.14128259687949	0.373392570077864	0.566731873785338	NA	NA	0.409521457468394	0.830644858617554	80.0364601852077
a6719	gain_cnaOV50	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	2.54084177725319	2.90989955040853	-0.369057773155339	0.377241090453072	0.833910663362688	0.46128712425982	0.978307460388516	0.442562722087207	0.566766845452605	NA	NA	0.0195519160727566	0.170685949197205	80.0364601852077
a6720	loss_cnaOV85	257	NPK76-II-72-1	PLK3	7	25	2.32630161961136	NA	3.03698601874243	3.28365918757196	-0.24667316882953	1.2004033984788	1.24557324595789	0.199465431600992	0.205491894759815	0.198039874114211	0.566930965468208	NA	NA	0.601140218613749	0.643974200352689	80.0399709796326
a6721	loss_cnaOV52, loss_cnaOV53	221	TAK-715	p38a	8	24	2.99573227355399	2.32630161961136	4.47418212225328	4.21252628931554	0.261655832937739	0.605422943276736	0.966803677047325	0.292150392512301	0.432186846969453	0.270640088727063	0.566960419759623	NA	NA	0.521793441569088	0.379686564345155	80.0399709796326
a6722	loss_cnaOV84	170	Shikonin	unknown	4	14	2.77258872223978	NA	-0.254721563401328	0.0582734025981036	-0.312994965999431	0.41468475388666	0.854618727543273	0.395698332087939	0.754778088815336	0.366239301704961	0.567213614875355	NA	NA	0.584596466525682	0.332135288214305	80.063803018836
a6723	loss_cnaOV55	186	Bexarotene	Retinioic acid X family agonist	4	14	2.07944154167984	NA	4.05708604821227	3.70044068062061	0.356645367591656	0.493285582824475	1.06258111978392	0.363432065863912	0.722999779457492	0.3356406028221	0.567332041052772	NA	NA	0.808119246657916	0.362467523060897	80.0686077817741
a6724	loss_cnaOV42	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-4.80434453477431	-4.05066734158339	-0.753677193190923	0.595913319394024	2.48061718822025	0.320432122313815	1.264742989731	0.303826481881172	0.567563585544323	NA	NA	0.928090428275099	0.200185597303704	80.0764371841633
a6725	gain_cnaOV72_(ASXL1)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.78842564586521	4.47066318976289	0.317762456102312	0.507963834292808	0.95959252674102	0.344205847357918	0.625561181033104	0.331143112568312	0.567641435242591	NA	NA	0.528684344966091	0.346267712183374	80.0764371841633
a6726	loss_cnaOV33_(ZFHX3)	263	FR-180204	ERK	4	28	2.99573227355399	NA	5.00002361236842	4.78487118262071	0.21515242974771	0.706221013353703	0.754510161068957	0.286938311188527	0.304653112381907	0.285155112348509	0.567674384676119	NA	NA	0.765348964715222	0.601941712001835	80.0764371841633
a6727	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1069	EHT 1864	Rac GTPases	8	25	2.30258509299405	NA	4.41786096660346	4.16899278217255	0.248868184430915	1.05360728737842	0.957660827205036	0.253908920991878	0.236205830590017	0.259870903519407	0.5677250968218	NA	NA	0.209847649169454	0.5644650754769	80.0764371841633
a6728	gain_cnaOV94	1003	Camptothecin	TOP1	7	24	-2.30258509299405	NA	-3.85177759971557	-3.64432341192861	-0.207454187786957	1.54217771448517	1.78958043251224	0.119138899336013	0.134520286370635	0.115923366180155	0.567956076573587	NA	NA	0.245478626683726	0.768505264351428	80.0942135393631
a6729	SMARCA4_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-1.15468735331349	-2.07331431317944	0.91862695986595	1.29028990531967	2.07296396423136	0.45217177033032	0.711953922973894	0.443146613118559	0.568125853877036	NA	NA	0.27860031514446	0.34841704892568	80.0942135393631
a6730	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	2.90460165669225	2.17336306780654	0.731238588885712	1.39476335645044	1.83556488847676	0.409699902332169	0.524274304672482	0.398372508363097	0.568184687364725	NA	NA	0.110753573262142	0.340834082095697	80.0942135393631
a6731	ARID1A_mut	1219	PFI-1	BRD2, BRD3, BRD4	9	23	2.30258509299405	NA	2.55528227727436	2.28579143233118	0.269490844943181	0.963565686148997	0.83180050451076	0.310153928078365	0.27968082385772	0.32398495009532	0.568188782340814	NA	NA	0.608145356284371	0.47351813652502	80.0942135393631
a6732	loss_cnaOV35	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.665652497117953	0.212458284541078	0.453194212576874	1.07306275876721	1.14475390315267	0.399023660812293	0.422337098994591	0.395887894619769	0.568525410337137	NA	NA	0.147050093426343	0.423680795573848	80.1293964777084
a6733	loss_cnaOV42	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	1.33583488503418	0.604765379262522	0.73106950577166	1.91602970658528	2.35659247859936	0.315618154564762	0.381554369047107	0.310223134636401	0.568607271905524	NA	NA	0.945873684522333	0.523634562992475	80.1293964777084
a6734	gain_cnaOV94	1020	Lenalidomide	TNFA	7	24	1.6094379124341	NA	4.65833705929318	4.32455464537149	0.333782413921687	0.784706433801581	0.759672983490021	0.436362777218106	0.425359598881645	0.439376443780129	0.568705089398916	NA	NA	0.0432145150424995	0.343229899356011	80.131279861287
a6735	loss_cnaOV82	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.24857682194998	1.49460389019656	0.753972931753421	1.02642080545289	1.65304073245495	0.465751811149226	0.734565129377653	0.456112736335109	0.568848946272586	NA	NA	0.0790070093513037	0.336078382810944	80.1396487304065
a6736	MLL2_mut	1026	17-AAG	HSP90	3	30	0	NA	-2.76199037836731	-0.307716336282323	-2.45427404208499	1.81883808824637	2.22195967456016	1.11650079319748	1.34936367230537	1.1045538180484	0.569096606400189	NA	NA	0.0614385017334621	0.129595127908117	80.1567909915434
a6737	loss_cnaOV55	1114	Cetuximab	EGFR	8	24	4.18661983833127	NA	5.9883661947712	5.7670573599109	0.221308834860304	1.59718347032003	1.18563858478782	0.171102078637238	0.138561936667151	0.186657922321167	0.569139585186808	NA	NA	0.571211011604741	0.72639417179866	80.1567909915434
a6738	TP53_mut	224	AS605240	PI3Kgamma	22	10	2.99573227355399	2.32630161961136	3.2639908040109	3.61954366008761	-0.355552856076707	1.6862256390232	1.64492123419943	0.212404609755505	0.210857223285178	0.216151903619721	0.569301912941164	NA	NA	0.629991442406632	0.58088218824781	80.1677533742608
a6739	loss_cnaOV38	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	2.53574576401325	2.03353727756662	0.502208486446631	0.733223107220179	1.67205568819186	0.324358550349862	0.684932705340699	0.300353923612265	0.569564313639264	NA	NA	0.947774780606575	0.392522211790207	80.1789232384115
a6740	loss_cnaOV16, loss_cnaOV17	1192	GSK269962A	ROCK1, ROCK2	6	26	1.6094379124341	NA	2.27149310409799	2.4784579483928	-0.206964844294804	2.31377062646386	1.2308407859623	0.140993845817794	0.0894491623014114	0.16814916003372	0.569774826999437	NA	NA	0.240431720692997	0.839311036434446	80.1789232384115
a6741	loss_cnaOV40	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-3.59047823804121	-4.08698788805439	0.49650965001318	2.30329093039047	1.71193962995233	0.271282276700612	0.215565321541473	0.290027546138998	0.569971625049894	NA	NA	0.590832014742361	0.7082412705881	80.1789232384115
a6742	gain_cnaOV4_(KRAS)	277	ABT-869	VEGFR and PDGFR family	8	24	0.0237165266173161	NA	2.81432033473509	2.68327437695152	0.131045957783575	0.622547365896892	0.5545392194664	0.229449277432414	0.210499577963484	0.236315039916694	0.570012740305092	NA	NA	0.135859222771583	0.607039659298527	80.1789232384115
a6743	gain_cnaOV51_(MYC)	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	3.62339268935753	3.96126261503282	-0.337869925675294	1.22021832661752	1.68204520583825	0.211500935630988	0.276893010295853	0.200868516792874	0.570023849167921	NA	NA	0.715792051468138	0.566538737241051	80.1789232384115
a6744	gain_cnaOV51_(MYC)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	8	24	1.63315443905142	NA	2.61277825240671	2.94743035421658	-0.334652101809876	0.386738866644876	0.883685791077939	0.420426039138184	0.865317997937796	0.378700331258762	0.570051890754084	NA	NA	0.0195626877124583	0.150702385753507	80.1789232384115
a6745	NF1_mut	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.65153830800116	2.2461620191059	0.405376288895266	0.716373954561469	1.30775668420821	0.321849253331702	0.565872455739152	0.309978372728184	0.570134712260247	NA	NA	0.844626166199295	0.387479126470487	80.1789232384115
a6746	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-2.47902416051405	-2.06010293689118	-0.418921223622874	1.61980568244398	1.23912923204381	0.323602667473512	0.258624369677973	0.338077105107034	0.570173054353985	NA	NA	0.607782797138556	0.606412697227085	80.1789232384115
a6747	loss_cnaOV20	333	T0901317	LXR	5	27	2.32630161961136	NA	5.18684748396311	4.67307476389923	0.513772720063873	0.975402511968074	1.13183800641766	0.461921184834687	0.526728928580706	0.453927785734988	0.570243791175691	NA	NA	0.00513856827479687	0.331423592269218	80.1789232384115
a6748	SMAD4_mut	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.96723166662856	5.70156842664776	0.265663239980793	1.10688533457377	0.55092061782711	0.439753641891631	0.240009720684477	0.482216913624684	0.57032985281336	NA	NA	0.192647393879073	0.719506053630389	80.1789232384115
a6749	TP53_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	17	6	2.30258509299405	NA	3.91780578578842	3.67164927894942	0.246156506839002	0.901239710977867	0.836783902179941	0.277729221562908	0.273131003705902	0.294169744658961	0.570369516389126	NA	NA	0.939921637730875	0.558199512786762	80.1789232384115
a6750	loss_cnaOV58	1022	AZD7762	CHEK1, CHEK2	5	26	0.693147180559945	NA	-0.883321779648302	-0.802379944062782	-0.0809418355855198	0.902719877786199	0.797533466166304	0.0995776310344928	0.0896643993084753	0.101490205764784	0.570395270459812	NA	NA	0.0789601813048709	0.858679462462606	80.1789232384115
a6751	gain_cnaOV4_(KRAS)	222	BX-912	PDPK1 (PDK1)	8	24	2.32630161961136	NA	3.19474011990523	3.48164288298847	-0.286902763083239	1.63752016672542	1.06788296145838	0.234257966108323	0.175205636494214	0.268664988053956	0.570558797052025	NA	NA	0.32708197481654	0.65373931978002	80.1805439429302
a6752	loss_cnaOV57_(ZNRF3)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.77456622888293	2.22487036478423	-0.4503041359013	1.83560104560791	1.22769617680878	0.345379840064755	0.24531699683804	0.366787927182277	0.570585433448839	NA	NA	0.686744228278817	0.663494479827484	80.1805439429302
a6753	loss_cnaOV84	344	THZ-2-49	CDK9	6	26	2.99573227355399	NA	2.23773020059489	2.66789008970726	-0.430159889112363	2.38390489849141	2.33983903866713	0.183261934340389	0.180443393268154	0.183841658337918	0.570752885337363	NA	NA	0.386302686012632	0.70060978198317	80.1805439429302
a6754	loss_cnaOV82	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.33582737540448	2.79176270064192	-0.455935325237433	0.882189958588129	1.73152708229503	0.270063733187365	0.516822166018665	0.263314001784552	0.570922578773879	NA	NA	0.321646334434405	0.492567286587764	80.1805439429302
a6755	loss_cnaOV52, loss_cnaOV53	226	GSK1070916	AURKB	8	24	0.940007258491471	2.32630161961136	2.54344530883652	2.23747807237158	0.30596723646494	1.01338987842925	1.55845519369739	0.211052524123335	0.301924504060755	0.196327259007711	0.571093051919021	NA	NA	0.821068836203746	0.530786125947597	80.1805439429302
a6756	NF1_mut	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	1.93791662316137	2.43996840768338	-0.502051784522013	0.556816956214127	1.36285323781203	0.384195160531792	0.901646005781738	0.368382868083451	0.571208864791743	NA	NA	0.110273099708812	0.213748383893519	80.1805439429302
a6757	PIK3R1_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.60658731807917	1.76121722930344	-0.154629911224263	1.07168999344767	1.78943743636223	0.0902263529761635	0.144286045563244	0.086412583129261	0.571266556257618	NA	NA	0.229584611811554	0.798242443638355	80.1805439429302
a6758	SMARCA4_mut	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	1.68507689295887	0.762504533400187	0.922572359558688	3.68003813567732	1.89575297438894	0.444670868759936	0.2506964127938	0.486652202065547	0.571275957497453	NA	NA	0.416319174042794	0.708271277401836	80.1805439429302
a6759	gain_cnaOV95_(MECOM)	1066	AZD6482	PI3Kbeta	8	25	1.6094379124341	NA	2.63078040959255	2.29858028154893	0.332200128043622	1.16295714025795	1.34917205935633	0.253696275764409	0.285651221823996	0.246225176203329	0.571330473722913	NA	NA	0.110274270716937	0.510702454304976	80.1805439429302
a6760	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	308	XL-880	MET	3	29	1.63315443905142	NA	0.498506873574452	0.227711317308495	0.270795556265957	0.118349353364472	1.00951113075509	0.277522988159898	2.28810338686015	0.268244250128682	0.571391813540384	NA	NA	0.36863251936328	0.185256495383897	80.1805439429302
a6761	PIK3R1_mut	341	EX-527	SIRT1	5	26	2.99573227355399	NA	5.52108321661179	5.82181902163559	-0.3007358050238	0.272184773139618	0.59078873301038	0.539175070260427	1.10489577192306	0.509041199027938	0.571428533117192	NA	NA	0.110917856765608	0.0971173779208884	80.1805439429302
a6762	loss_cnaOV57_(ZNRF3)	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.33313527074091	2.53620292418936	-0.203067653448447	0.721405223861839	0.619918105764772	0.321919800213223	0.281489025490253	0.327571741428538	0.571496188015885	NA	NA	0.858206946291067	0.623192487115598	80.1805439429302
a6763	loss_cnaOV43_(NF1)	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.27527488336477	1.87713482157807	0.398140061786695	0.709990704561289	1.41737823732989	0.296073336315933	0.560767992072108	0.280898952235026	0.571505361445314	NA	NA	0.839164652744848	0.361703104153597	80.1805439429302
a6764	loss_cnaOV35	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	2.30258509299405	NA	1.81950195945952	2.23354826797725	-0.414046308517733	1.61387301179655	1.24684649018835	0.317610570182362	0.256554453473896	0.332074807745728	0.571635438383142	NA	NA	0.686753638033125	0.610412951362265	80.1869366488559
a6765	loss_cnaOV41	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.58678072761356	4.25703732364004	0.329743403973522	1.06669794982345	0.763224055365578	0.41219237521484	0.309125375208697	0.432040108871539	0.571970433715395	NA	NA	0.225449634190675	0.587809518246269	80.2085497616671
a6766	loss_cnaOV42	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.58678072761356	4.25703732364004	0.329743403973522	1.06669794982345	0.763224055365578	0.41219237521484	0.309125375208697	0.432040108871539	0.571970433715395	NA	NA	0.225449634190675	0.587809518246269	80.2085497616671
a6767	gain_cnaOV96	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.21834325660415	1.54944186336782	-0.331098606763672	1.07850663451127	1.79216866713752	0.193143019775224	0.306997283251495	0.184747458671123	0.572076664825501	NA	NA	0.316470571988992	0.590526452088348	80.2085497616671
a6768	loss_cnaOV52, loss_cnaOV53	1377	Afatinib (rescreen)	ERBB2, EGFR	9	24	2.30258509299405	NA	2.32379721029886	2.77935217793759	-0.45555496763873	1.98467466416515	1.59496086908774	0.267330987036901	0.229536344603038	0.285621407062664	0.572135248066284	NA	NA	0.640279298076295	0.548132915706839	80.2085497616671
a6769	loss_cnaOV34	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	4.39047255314615	4.56019329174657	-0.169720738600427	1.44331513633807	0.942563348191576	0.165810333889513	0.117590908823306	0.180062951658429	0.572263835576501	NA	NA	0.191674806136794	0.810964749788298	80.2085497616671
a6770	loss_cnaOV41	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.98463381439373	3.27508195364916	-0.29044813925543	1.20216882792634	1.24153598651838	0.234922082951887	0.241603452450547	0.233942585965573	0.572367605697562	NA	NA	0.601198061827539	0.639964803890494	80.2085497616671
a6771	PTEN_mut	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	0.31300909873312	-0.117135769458298	0.430144868191418	0.248401446693032	1.00980751137445	0.447506980485944	1.73165202505032	0.425967190129084	0.572450988776748	NA	NA	0.549241002838163	0.0728099911265819	80.2085497616671
a6772	SMAD4_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.8386196757947	2.21538096524175	-0.376761289447048	1.99420693332811	1.20220631706703	0.288353943651818	0.188927880627852	0.313391540285876	0.572465787438088	NA	NA	0.686761055166477	0.73498359970478	80.2085497616671
a6773	loss_cnaOV41	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	5.38022325061526	5.56810182620793	-0.187878575592667	2.0074814313149	0.708408464563654	0.190539842856632	0.0935891972209213	0.265212211585292	0.572609130395984	NA	NA	0.304546899020843	0.845764987007567	80.2167882741856
a6774	loss_cnaOV42	333	T0901317	LXR	4	28	2.32630161961136	NA	5.2179792153977	4.68697639941086	0.531002815986838	1.20659622390265	1.1033991828632	0.476599419329453	0.440083273482614	0.481242712731527	0.572913801920275	NA	NA	0.00514160444007737	0.455115998259433	80.2283052141977
a6775	PIK3R1_mut	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-1.35518527662087	-1.12801715840593	-0.227168118214934	1.36031143623588	1.3363142122849	0.169412358183404	0.166997139157729	0.16999603545824	0.57297283151858	NA	NA	0.0495050446285456	0.750899860456565	80.2283052141977
a6776	loss_cnaOV43_(NF1)	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.12486998476541	3.81289920389018	0.311970780875229	1.33310465969882	0.825809085964253	0.351826980442295	0.234018221004275	0.377775912347776	0.573133586903472	NA	NA	0.939928701845657	0.72792945328748	80.2283052141977
a6777	loss_cnaOV44	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	4.12486998476541	3.81289920389018	0.311970780875229	1.33310465969882	0.825809085964253	0.351826980442295	0.234018221004275	0.377775912347776	0.573133586903472	NA	NA	0.939928701845657	0.72792945328748	80.2283052141977
a6778	RB1_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	3.69936642120878	4.24851360629181	-0.549147185083036	0.441908828169906	0.994808355295145	0.567403061096105	1.24267077296745	0.552013040662603	0.573259656483633	NA	NA	0.0482996166284425	0.14739970366259	80.2283052141977
a6779	PIK3R1_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	3.8728386566455	4.06229198108118	-0.189453324435685	1.65771938935011	1.48395581287867	0.125608741516704	0.114285521212344	0.127667766648774	0.573436565152628	NA	NA	0.330112086116098	0.820536136196712	80.2283052141977
a6780	loss_cnaOV16, loss_cnaOV17	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	1.6094379124341	NA	1.45425274991842	1.10423413389353	0.350018616024887	1.7803810841801	1.43790110854684	0.233588108873797	0.196597581908189	0.243423288252848	0.573563633386832	NA	NA	0.813216287493756	0.667236627853182	80.2283052141977
a6781	NF1_mut	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	3.75291718479686	4.01226361155785	-0.259346426760991	1.05450398674305	0.723029454336472	0.340042822076556	0.245941627553263	0.3586941378467	0.573608957734316	NA	NA	0.525902510530938	0.662797950339199	80.2283052141977
a6782	loss_cnaOV43_(NF1)	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	2.77292229603846	2.22681631609587	0.546105979942598	0.541829976729348	1.29201096045775	0.444791388050016	1.00789178044201	0.422679061289942	0.573847966138061	NA	NA	0.389813535885962	0.261819069857744	80.2283052141977
a6783	gain_cnaOV48_(SOX17)	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	8.20550451158964	8.81665189870067	-0.611147387111036	1.40784856308505	1.73381357184045	0.356702465776054	0.434100231470788	0.35248737063599	0.573872500384406	NA	NA	0.921857892928554	0.540875060885471	80.2283052141977
a6784	loss_cnaOV54	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	10	22	2.99573227355399	NA	4.13390168887175	3.98668454016827	0.147217148703485	1.17003390023861	1.63195744576372	0.0976041613635841	0.125822977157724	0.09020893840439	0.573886731784428	NA	NA	0.33011829218623	0.774421227263132	80.2283052141977
a6785	PIK3CA_mut	1067	CCT007093	PPM1D	7	26	1.88706964903238	NA	4.1378679325073	4.58445955645457	-0.44659162394727	0.775697537350987	0.655270452125455	0.656516007446345	0.575729072793481	0.681537863486278	0.573950986718376	NA	NA	0.0816809348867139	0.198553301271325	80.2283052141977
a6786	loss_cnaOV44	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.82422526948685	4.40381724778132	0.420408021705528	1.42714873019441	0.974869022636724	0.416172363045057	0.294578983122704	0.431245646280207	0.573991730835714	NA	NA	0.375294747714452	0.663590963173243	80.2283052141977
a6787	loss_cnaOV85	1264	SGC0946	Q8TEK3 (DOT1L)	7	26	-0.693147180559945	NA	2.29715696513263	2.06635393637315	0.230803028759483	0.674522834361652	0.522458848612293	0.4157482883792	0.34217229870047	0.441763077364888	0.574052558527955	NA	NA	0.0424742397716634	0.425167235805455	80.2283052141977
a6788	gain_cnaOV51_(MYC)	152	CP466722	ATM	8	24	2.77258872223978	NA	2.5396078119958	2.68268630935237	-0.143078497356565	0.458697450094202	0.899423430098899	0.174889758702548	0.31192346355355	0.159078018837949	0.5741409607267	NA	NA	0.55623367474287	0.564550539237839	80.2283052141977
a6789	gain_cnaOV50	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.06545256040702	4.25192748432804	-0.186474923921019	0.821965640760646	1.00013591582262	0.189448479154909	0.226864621431689	0.186449582472641	0.57422250850807	NA	NA	0.209929162029879	0.698922552939468	80.2283052141977
a6790	loss_cnaOV41	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	4.69916827512992	4.23801957562612	0.461148699503808	1.44774034262839	1.28781736145656	0.352142750102314	0.318529978011518	0.358085481144806	0.574240137766868	NA	NA	0.371459037184589	0.53342522736611	80.2283052141977
a6791	loss_cnaOV54	157	JNK-9L	JNK	6	13	1.63315443905142	NA	-0.323320379248801	0.103186994080115	-0.426507373328916	0.712542237198936	1.0965153560124	0.426925295271048	0.598571356282755	0.388966165398685	0.574309117957654	NA	NA	0.191106038723578	0.327314331436499	80.2283052141977
a6792	loss_cnaOV56	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	2.7313711617288	2.95115949851609	-0.219788336787283	0.187449410139101	0.900971523681432	0.255881719772698	1.17252082374751	0.243945930598575	0.574480164117084	NA	NA	0.33047054021436	0.349526722731633	80.2283052141977
a6793	loss_cnaOV54	201	Epothilone B	Microtubules	6	13	-3.44201937618241	NA	-5.20096725659057	-4.40169547802813	-0.799271778562431	0.893648538736784	2.3713117384566	0.389812371037633	0.894391635991753	0.337058922114832	0.574533581045767	NA	NA	0.350417768846378	0.303014344219991	80.2283052141977
a6794	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	1.49094094374515	1.11018333556822	0.38075760817693	2.49956127706886	1.2852508569327	0.25412692592375	0.152329775497014	0.296251588647543	0.574549072425554	NA	NA	0.81322133444633	0.754558075237448	80.2283052141977
a6795	PIK3CA_mut	225	Genentech Cpd 10	AURKA, AURKB	6	26	2.32630161961136	NA	2.16127571348612	3.00173946033785	-0.840463746851733	1.68541549047595	1.86620276939459	0.4574432023543	0.498668578520297	0.450360357746326	0.574551552489002	NA	NA	0.346714872563302	0.311913501748033	80.2283052141977
a6796	loss_cnaOV21, loss_cnaOV22	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.10928531816225	0.721951886802326	0.387333431359927	0.422151959534859	1.08110990174353	0.368845571405061	0.91752133944067	0.358273872744359	0.574992412029472	NA	NA	0.772112789163394	0.270249163888409	80.2614718610344
a6797	PTEN_mut	309	Y-39983	ROCK	3	29	2.99573227355399	NA	4.96794213518228	4.96391174734574	0.00403038783654353	0.683907376415565	1.27828309521729	0.00323077230066481	0.00589317790029878	0.00315296967598435	0.575019812611826	NA	NA	0.3729823853264	0.993474323507217	80.2614718610344
a6798	loss_cnaOV81_(RB1)	293	MP470	PDGFR	4	28	2.99573227355399	NA	4.4605831986762	3.99047980309443	0.470103395581771	0.541973545124097	1.86137121842796	0.264973963182377	0.867391775504706	0.25255757203488	0.575042844012487	NA	NA	0.622498041778426	0.305047246213635	80.2614718610344
a6799	loss_cnaOV83	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	4.17085233465914	3.87158929913632	0.299263035522819	0.500376569301849	1.30566831169123	0.244008811622466	0.598075637195334	0.229202955178704	0.575169209078079	NA	NA	0.699001241180102	0.391306645818478	80.2673017480641
a6800	loss_cnaOV85	1031	Elesclomol	HSP70	7	24	-1.6094379124341	NA	-3.79622973013195	-4.13663969582898	0.340409965697026	2.09579563523413	1.34439161645812	0.222427930928455	0.162425171602668	0.253207444564298	0.575485633634825	NA	NA	0.864202943156423	0.696038107264846	80.2996496277016
a6801	loss_cnaOV82	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.81173443920943	3.45509762309971	0.356636816109721	0.669956039336434	1.14433110160976	0.318968018255746	0.53232868303263	0.311655267962246	0.575571405983265	NA	NA	0.727026833814593	0.47312657711808	80.2998089668719
a6802	loss_cnaOV52, loss_cnaOV53	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	1.38629436111989	NA	0.921028037615125	1.32669612308304	-0.405668085467916	1.56665131672824	1.09605213176942	0.328532496525686	0.258939612877679	0.370117509659893	0.575687078801131	NA	NA	0.267332740613698	0.489971746075945	80.3005612232588
a6803	loss_cnaOV54	304	SB52334	ALK5	10	22	2.99573227355399	NA	4.45238925451412	4.32766375902909	0.124725495485027	1.07216916590863	1.06840210512709	0.116616713639068	0.116330052617514	0.11674021876828	0.575746060393934	NA	NA	0.352221439273631	0.763711285067631	80.3005612232588
a6804	loss_cnaOV70	219	AT-7519	CDK9	3	29	2.32630161961136	NA	2.14138480309811	1.43112042016061	0.710264382937503	1.20543884797623	1.73561501635673	0.416478314902927	0.589216436926637	0.409229222058953	0.575924119094272	NA	NA	0.31652353796068	0.423973635673462	80.3088872305727
a6805	gain_cnaOV95_(MECOM)	152	CP466722	ATM	9	23	2.77258872223978	NA	2.51875268330149	2.69706781611782	-0.178315132816324	0.755029408578361	0.837625224128318	0.218411799003695	0.236169784634047	0.212881761054759	0.576088398426584	NA	NA	0.556255716607981	0.568530385672979	80.3088872305727
a6806	loss_cnaOV33_(ZFHX3)	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.20900229093166	2.86217338377798	0.346828907153682	1.19171807418673	0.780366002938437	0.407369285907619	0.29103268186175	0.444443896643001	0.576125636352827	NA	NA	0.330503252905153	0.610377400719429	80.3088872305727
a6807	TP53_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	21	10	2.30258509299405	NA	4.58520907252086	4.35722181841209	0.227987254108768	1.02819141260655	0.629943553538224	0.246961445268057	0.221736197475917	0.361916957207078	0.576144316841104	NA	NA	0.528789493895429	0.453959414267044	80.3088872305727
a6808	loss_cnaOV43_(NF1)	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.62538973838421	3.21152444981579	0.413865288568425	0.969949103046324	1.04845309664986	0.398587859445734	0.426687634710518	0.394738963422259	0.576350405512475	NA	NA	0.0921965190222507	0.420898914974692	80.3152127702567
a6809	gain_cnaOV95_(MECOM)	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	2.60221823275019	2.3894443188045	0.212773913945685	0.803457425235722	0.871743489773217	0.248519373938144	0.264822885771776	0.244078580960826	0.57635899020668	NA	NA	0.62240278605494	0.633243975176295	80.3152127702567
a6810	loss_cnaOV83	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.22301928961401	1.54857593132896	-0.32555664171495	1.13741419343222	1.78672235994111	0.189893636934462	0.286225232281094	0.18220885853003	0.576651525755117	NA	NA	0.316533473322043	0.609958792526622	80.3441776865621
a6811	gain_cnaOV18_(CCNE1)	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.60572651074617	2.19907221076801	0.406654299978153	1.36951150526222	1.41004465511391	0.289942577521522	0.296933832549505	0.288398171294299	0.576773684589323	NA	NA	0.747303515718278	0.625131496139214	80.3493991959742
a6812	loss_cnaOV56	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.70507230831358	3.23182385903471	0.47324844927887	1.11620915323477	1.03450582751094	0.45497991455193	0.423978291082272	0.457463299571278	0.576876694980482	NA	NA	0.0922011976658982	0.544357300741698	80.3519520256471
a6813	loss_cnaOV41	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.0489849802355	3.34937752780659	-0.300392547571089	0.944284160293744	1.13382448177856	0.270520753317817	0.318116685847663	0.264937432908382	0.577009714149689	NA	NA	0.950969405906352	0.549475686504622	80.3524471736473
a6814	loss_cnaOV102	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.70482460252621	3.23184948377134	0.472975118754869	1.3331202186009	1.01601101070597	0.454712209861661	0.35478804698593	0.46552164668592	0.577181626460515	NA	NA	0.0922039046510916	0.605256309645466	80.3524471736473
a6815	BRCA1_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.82396395201864	1.28803351958011	0.535930432438529	0.921450555608611	1.38020741418236	0.3959384707715	0.581616050016434	0.388297024730892	0.577185241506761	NA	NA	0.581193948395188	0.431127247840741	80.3524471736473
a6816	loss_cnaOV58	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	3.79943035637255	3.91714611264369	-0.11771575627114	1.65025779432338	1.48810892830537	0.077427852045451	0.0713317377903397	0.0791042604691524	0.577479372144956	NA	NA	0.0699739612688911	0.890215944122112	80.3524471736473
a6817	gain_cnaOV4_(KRAS)	140	Vinorelbine	Microtubules	6	13	-2.74887219562247	NA	-3.76768704315452	-3.31288054607113	-0.454806497083387	2.20644467120326	1.5661514741789	0.255715499300777	0.206126400094756	0.290397515554382	0.577620297794869	NA	NA	0.68182642076895	0.662255757033063	80.3524471736473
a6818	loss_cnaOV70	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.44704782422203	2.90192204554683	-0.454874221324804	0.486146740823269	1.15330973226454	0.40568447297221	0.935672674786411	0.394407684769686	0.577647060655429	NA	NA	0.391197712582877	0.255211608647077	80.3524471736473
a6819	loss_cnaOV16, loss_cnaOV17	305	TPCA-1	IKK	6	26	2.99573227355399	NA	3.06881036181813	3.38436069980665	-0.31555033798852	0.92342361333159	1.2873249240864	0.255682586130388	0.341717856715897	0.245120973022769	0.577747553441633	NA	NA	0.993617354547448	0.502464326483417	80.3524471736473
a6820	gain_cnaOV94	329	QL-XI-92	DDR1	7	25	2.32630161961136	NA	4.80922897868656	4.45651915168329	0.352709827003262	1.19660332420191	0.963537981140601	0.347687887109354	0.294759190342804	0.36605700440136	0.577776903483838	NA	NA	0.191743392910683	0.492774694281667	80.3524471736473
a6821	loss_cnaOV40	1149	TW 37	BCL2, BCL2L1	8	25	1.6094379124341	NA	-0.455472988039115	-0.831566637498525	0.376093649459411	0.966054165040576	0.901093805460901	0.410508656129154	0.389309070929386	0.417374580959462	0.577819749884415	NA	NA	0.0421087871679328	0.350704753981688	80.3524471736473
a6822	gain_cnaOV95_(MECOM)	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	4.33402716258449	3.81736628990208	0.516660872682412	0.796933901294508	1.72188920769137	0.332347870289596	0.64831082206839	0.300054655302199	0.577820653778034	NA	NA	0.743465931246982	0.38844461105398	80.3524471736473
a6823	loss_cnaOV70	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	2.92552100789027	2.32447290972642	0.601048098163848	1.44907292077898	1.29505165574968	0.460383823116114	0.414781126294694	0.464111292777673	0.577830029977065	NA	NA	0.110336159379153	0.551787740754275	80.3524471736473
a6824	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	172	Embelin	XIAP	3	16	3.46573590279973	NA	2.77156451858551	3.15918515603537	-0.387620637449855	1.29026037858908	0.905174322114936	0.404385593695591	0.300420476271405	0.428227610947006	0.577946024740415	NA	NA	0.671406199273966	0.660782385676628	80.3524471736473
a6825	loss_cnaOV85	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	4.91380756426018	4.71033511857751	0.20347244568267	1.46764673411205	1.16711730618372	0.164713796159671	0.138638570817776	0.174337613369808	0.57807765212275	NA	NA	0.425304301142527	0.744412555674769	80.3524471736473
a6826	loss_cnaOV41	1026	17-AAG	HSP90	5	28	0	NA	0.2879319376584	-0.677040032566558	0.964971970224958	1.80962032615572	2.35049781366209	0.421771263312422	0.533245541220739	0.410539403447275	0.578126263412692	NA	NA	0.0615004306271321	0.332223096788532	80.3524471736473
a6827	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1031	Elesclomol	HSP70	8	23	-1.6094379124341	NA	-3.79851701984044	-4.15064455009111	0.352127530250673	2.03331785366023	1.3293103879894	0.23026741992583	0.173178792295951	0.264894890939106	0.578150538110707	NA	NA	0.864213584926538	0.658283109248131	80.3524471736473
a6828	loss_cnaOV44	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	3.9749090752801	4.31694999207326	-0.342040916793159	0.499251984464133	0.838232862669732	0.417443966832132	0.685106774608587	0.408049996636704	0.578611090118786	NA	NA	0.317327913062961	0.367186322002288	80.4027154183682
a6829	gain_cnaOV50	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	2.40189498442389	2.877372291213	-0.475477306789104	2.09536679167972	1.4967764543596	0.303868948142411	0.226918412889394	0.317667548419939	0.578797733719984	NA	NA	0.968839809668192	0.687054612117559	80.4027154183682
a6830	gain_cnaOV50	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	0.638391647240848	0.872213083271595	-0.233821436030747	0.858343217314698	1.39696739485242	0.172659067861287	0.272410186641016	0.167377876457488	0.578842210537773	NA	NA	0.163680166346119	0.658874093025028	80.4027154183682
a6831	gain_cnaOV19	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	5.01596867640735	4.77221918354186	0.243749492865494	0.594997845426542	0.670442032192273	0.36616699816834	0.409664496668479	0.363565351158636	0.578957193234275	NA	NA	0.76231116693554	0.559915610554819	80.4027154183682
a6832	loss_cnaOV58	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	3.57911253249511	4.1166857077757	-0.537573175280592	1.30820083761292	1.52333249828472	0.359235591075633	0.410925570313427	0.352892868684875	0.579005823464428	NA	NA	0.330188193045825	0.441800592660743	80.4027154183682
a6833	SMARCA4_mut	219	AT-7519	CDK9	3	29	2.32630161961136	NA	0.787826095183315	1.57114373477248	-0.783317639589169	2.14302137122226	1.66658873582308	0.460097413513329	0.365520218373935	0.47001256083872	0.579089611646092	NA	NA	0.316566593389833	0.595310137833902	80.4027154183682
a6834	PIK3CA_mut	229	LY317615	PRKCB (PKCbeta)	6	26	2.99573227355399	2.32630161961136	2.11715992500487	2.89483234210768	-0.777672417102808	2.0606037420717	1.57343164925948	0.467194495000132	0.377400274116239	0.494252430646613	0.579332700034762	NA	NA	0.321761701027934	0.41674485949637	80.4027154183682
a6835	loss_cnaOV83	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	3.22217426008935	3.7248361263346	-0.502661866245251	3.95024352829104	1.54233076740763	0.246979131398053	0.127248323462911	0.325910548416364	0.579435276101546	NA	NA	0.747639036353996	0.792213343790272	80.4027154183682
a6836	loss_cnaOV70	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.60213387325763	4.81502968041942	-0.212895807161789	1.0517012473227	0.630192412526752	0.319357997807966	0.202429927418795	0.33782667472651	0.579628647176283	NA	NA	0.76231555994894	0.761405084703028	80.4027154183682
a6837	gain_cnaOV4_(KRAS)	158	PF-562271	FAK	6	12	0.940007258491471	NA	2.57873108344049	2.14479420775783	0.433936875682663	1.2050545525938	1.47630104406374	0.310575022103629	0.360097287503409	0.293935222377264	0.579664604371772	NA	NA	0.747342920924954	0.517382818560569	80.4027154183682
a6838	loss_cnaOV81_(RB1)	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-4.05603009074706	-4.71206193848376	0.6560318477367	0.654512587096508	1.45976060976471	0.462328417084873	1.0023212092023	0.449410570026577	0.57970845690582	NA	NA	0.135811624884159	0.22456707048386	80.4027154183682
a6839	loss_cnaOV16, loss_cnaOV17	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.83012525914044	3.39574676465768	0.434378494482763	0.993325954743325	1.1291779610657	0.389907393717132	0.437297034682846	0.384685593821547	0.580046976214569	NA	NA	0.773399915300729	0.544606065058394	80.4027154183682
a6840	loss_cnaOV41	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	4.85206945836487	4.47471238337274	0.377357074992133	1.39455626216765	0.944077317268162	0.371505627862343	0.270592937143736	0.399709926390432	0.580084221882401	NA	NA	0.191771716061327	0.588018230757783	80.4027154183682
a6841	loss_cnaOV54	238	CAL-101	PI3Kdelta	10	22	2.99573227355399	2.32630161961136	4.28996300788255	4.43143074424476	-0.141467736362214	1.03738864648301	0.970809730767609	0.142716064819171	0.136369081001438	0.145721382757832	0.580121467856077	NA	NA	0.511888714223156	0.71996574273348	80.4027154183682
a6842	gain_cnaOV4_(KRAS)	155	AP-24534	ABL	6	13	-0.669430653942629	NA	1.06513882002695	0.660894850283285	0.404243969743665	1.2876978097819	1.24799665650148	0.320878627812632	0.313927667402131	0.323914305088675	0.580160113713819	NA	NA	0.58482436217816	0.535856163828861	80.4027154183682
a6843	loss_cnaOV20	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.684395983783187	-1.43462184602005	0.750225862236858	2.03630124904579	1.83864738795129	0.402004813656016	0.368425773243726	0.408031396967743	0.580230565412196	NA	NA	0.0743958363592782	0.475470984572831	80.4027154183682
a6844	gain_cnaOV18_(CCNE1)	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	2.48126828802995	2.89599311062789	-0.414724822597945	1.9072331259174	1.85791542347027	0.222622523271797	0.217448416222562	0.223220506896546	0.58030527275294	NA	NA	0.346793035376753	0.704806010244247	80.4027154183682
a6845	loss_cnaOV39	196	Phenformin	AAPK1 (AMPK) agonist	9	22	8.29404964010203	NA	9.01109792781244	8.65376751582162	0.357330411990818	1.46493397979715	1.80155105338744	0.208319247726913	0.243922536386451	0.198345981546808	0.580332370036479	NA	NA	0.921872824548645	0.572188375217948	80.4027154183682
a6846	loss_cnaOV35	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	3.60558068864437	3.9802953849084	-0.374714696264022	1.0173010821104	1.25328194687915	0.30627909402023	0.368341981399126	0.298986750106082	0.580391583760148	NA	NA	0.699045395052795	0.493600861443209	80.4027154183682
a6847	loss_cnaOV55	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.75834591187844	4.54086275168783	0.21748316019061	0.672346226558868	1.00483501517775	0.229481491668796	0.323468997965095	0.216436685531045	0.580428250154088	NA	NA	0.943197036026517	0.512641208848186	80.4027154183682
a6848	loss_cnaOV56	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.78053438975969	3.45191478732579	0.328619602433893	1.41826151630889	0.860905545937472	0.362212603484767	0.231705929163999	0.381713887179165	0.580538824299348	NA	NA	0.794406077679931	0.729172960698696	80.4027154183682
a6849	gain_cnaOV50	1262	UNC1215	LMBL3	4	29	0	NA	2.71400218412747	2.7895727763205	-0.0755705921930341	0.567036918230648	0.490199856978955	0.151701283653363	0.133272790118923	0.154162819750228	0.580613346786494	NA	NA	0.110033053529566	0.813319759768342	80.4027154183682
a6850	loss_cnaOV87, loss_cnaOV88	1061	SB590885	BRAF	3	30	1.6094379124341	NA	4.26950903020714	3.89334290366112	0.376166126546016	2.05564112367601	1.21862342500302	0.291798362065951	0.18299211969127	0.308681187992988	0.580766223306502	NA	NA	0.573507516440869	0.783122442135162	80.4027154183682
a6851	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	333	T0901317	LXR	3	29	2.32630161961136	NA	5.25855307959698	4.70108954504496	0.557463534552014	1.14712745789249	1.11403423867311	0.499398037126405	0.485964772891226	0.500400719475183	0.580888181700359	NA	NA	0.00515051672255599	0.493372529598518	80.4027154183682
a6852	gain_cnaOV26	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.47450386332388	1.62895392350518	-0.154450060181294	0.469988750335827	0.700738188894013	0.224567199800544	0.328625015111389	0.220410507988818	0.580919626313258	NA	NA	0.209501624416383	0.643038202428711	80.4027154183682
a6853	loss_cnaOV57_(ZNRF3)	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.49075972623302	8.78792587068146	-0.297166144448445	1.01518544463816	1.26485360569164	0.239388204242321	0.292721045221804	0.234941137149188	0.58103925606185	NA	NA	0.530347391344187	0.622495903582557	80.4027154183682
a6854	gain_cnaOV51_(MYC)	290	KIN001-260	IKK	8	23	2.99573227355399	NA	5.02985684456812	4.78777323045835	0.242083614109772	0.977188895884693	0.877978583391035	0.26811057913807	0.247734716521316	0.275728381864131	0.581077702125958	NA	NA	0.665684539973367	0.548204557754871	80.4027154183682
a6855	loss_cnaOV57_(ZNRF3)	1005	Cisplatin	DNA crosslinker	4	27	1.79175946922805	2.30258509299405	3.48065504099908	2.95585182220967	0.524803218789414	1.36898887604849	1.166215720257	0.441457294117242	0.383350973825463	0.450005268899789	0.581088784583307	NA	NA	0.0888712331314885	0.509981008995804	80.4027154183682
a6856	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.65064390911092	3.26642022153871	0.384223687572209	0.605611081223848	1.13761947835712	0.346112280341647	0.634439658527634	0.337743590789323	0.581331084145613	NA	NA	0.950975423057662	0.404311912641316	80.4027154183682
a6857	TP53_mut	329	QL-XI-92	DDR1	22	10	2.32630161961136	NA	4.59235134629805	4.40458520243311	0.187766143864947	1.11212152440661	0.770118131261612	0.183793679857743	0.168835994757977	0.243814729510845	0.581401571127759	NA	NA	0.191787786860857	0.585629188885685	80.4027154183682
a6858	loss_cnaOV35	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-1.55449955628788	-2.2882455149044	0.733745958616519	4.39423413741456	2.35999976157808	0.273716578010306	0.166979258653758	0.310909335908525	0.581524242207935	NA	NA	0.417664692329126	0.802281322707316	80.4027154183682
a6859	gain_cnaOV95_(MECOM)	262	VX-11e	ERK	9	23	1.63315443905142	NA	3.02963315414805	2.79261671331269	0.237016440835362	1.15461911398307	1.11294271774329	0.210829798231375	0.205276734089158	0.212963737537147	0.581578300707647	NA	NA	0.391249915097149	0.606077069569073	80.4027154183682
a6860	gain_cnaOV94	295	NVP-BHG712	EPHB4	7	25	2.32630161961136	NA	3.30650957342287	3.23562340998817	0.0708861634346958	1.15683182111323	1.07958283943124	0.0647085358764766	0.0612761182230284	0.0656606986009903	0.581590069515301	NA	NA	0.0626306588313203	0.887576705298531	80.4027154183682
a6861	loss_cnaOV85	194	AUY922	HSP90	6	13	-1.36257783450257	NA	-2.02000147724072	-2.78818706801812	0.768185590777403	2.61551070252277	1.66585704422302	0.385497210037076	0.293703860602235	0.46113536178952	0.581602571782259	NA	NA	0.345950199090686	0.53036171809006	80.4027154183682
a6862	loss_cnaOV54	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	6	13	2.77258872223978	NA	-1.17530354428072	-0.289720643655586	-0.885582900625138	0.803526053285246	2.12615328965413	0.481632392465934	1.10212095426701	0.416518839415008	0.581648766562689	NA	NA	0.0429701470520073	0.207111216793473	80.4027154183682
a6863	loss_cnaOV84	1054	PD-0332991	CDK4, CDK6	6	27	1.38629436111989	0.693147180559945	2.84818236203146	2.1588177781428	0.689364583888655	1.78597233439051	1.78389787591259	0.386364744504604	0.385988388853689	0.386437246883316	0.581649939801401	NA	NA	0.110881948796391	0.419189242459304	80.4027154183682
a6864	ARID1A_mut	286	KIN001-236	TIE2	8	24	2.32630161961136	NA	4.84088864587105	4.77979804937365	0.0610905964974018	0.464916364716752	0.719901676622401	0.0912954009995552	0.131401260815203	0.0848596391440893	0.58179060855989	NA	NA	0.76232963525869	0.784717393508249	80.4027154183682
a6865	PTEN_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.2790185484708	1.34891689668207	-0.0698983482112736	0.436551520815803	1.43207654800961	0.0512739870353637	0.160114774266853	0.0488090865732163	0.581842307754653	NA	NA	0.58124548482521	0.844971417031848	80.4027154183682
a6866	PIK3CA_mut	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-2.26203265391231	-2.34910651326562	0.0870738593533029	0.360885745277206	0.851561411524346	0.113826798174157	0.241278189822707	0.10225200223368	0.581919102636349	NA	NA	0.674830458541474	0.758976994916745	80.4027154183682
a6867	loss_cnaOV52, loss_cnaOV53	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	1.02621045756671	0.755525628680121	0.270684828886592	0.224726998215624	1.15864315021539	0.250227498334114	1.20450515975331	0.233622257928399	0.581928176034933	NA	NA	0.356271449410827	0.432737312710858	80.4027154183682
a6868	loss_cnaOV56	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	1.01275616940723	0.517807938463621	0.494948230943609	1.99475228980654	1.13418681797213	0.407937883203028	0.248125159937333	0.436390392747248	0.582006328621156	NA	NA	0.431403192467756	0.711337198663332	80.4027154183682
a6869	loss_cnaOV42	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	5.93404731288249	5.69682107575503	0.237226237127464	0.997763451374881	0.542869175588923	0.392772969703486	0.237757994443047	0.436986013932571	0.582071259620822	NA	NA	0.192793132242992	0.67076557815849	80.4027154183682
a6870	loss_cnaOV21, loss_cnaOV22	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.15620197931447	3.90395775987589	0.252244219438584	0.429820880399383	0.748624702112125	0.344734684194825	0.586858924127191	0.336943489477327	0.582339410211632	NA	NA	0.955834455588056	0.432995350941765	80.4214482119703
a6871	loss_cnaOV81_(RB1)	306	TG101348	JAK2	4	28	2.32630161961136	NA	3.23581355458631	2.7652364844806	0.470577070105705	1.38128327447453	1.40119447703781	0.336314789175091	0.340681074477445	0.335839940720097	0.582432164915344	NA	NA	0.627807530248862	0.559744451624343	80.4214482119703
a6872	MLL2_mut	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.0185430549193598	-0.0680046891428197	0.0494616342234599	0.766748534868225	0.98529257270882	0.0508732397700143	0.0645082865818067	0.0501999462834448	0.582495157937863	NA	NA	0.54935503279906	0.924852887792693	80.4214482119703
a6873	SMAD4_mut	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	7.02659239036682	6.63596352406045	0.390628866306372	0.526494513015659	1.61518587031375	0.25566183135223	0.741942900922035	0.241847624775526	0.582698917557664	NA	NA	0.337847257999917	0.456174009004342	80.4214482119703
a6874	RB1_mut	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.1698300468321	3.96019171456245	0.209638332269646	0.323721551877389	0.787335139386906	0.273959441417621	0.647588432261834	0.266263147397296	0.582708236959098	NA	NA	0.52600922174642	0.416971732485165	80.4214482119703
a6875	loss_cnaOV39	221	TAK-715	p38a	9	23	2.99573227355399	2.32630161961136	4.45564799141242	4.20840243473423	0.247245556678194	1.26941765891605	0.713125313717578	0.275972697663865	0.194770850193872	0.346707025991383	0.582773171660314	NA	NA	0.521982078758009	0.593504745261642	80.4214482119703
a6876	loss_cnaOV70	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.462773847808618	0.180307736044365	-0.643081583852983	1.68506530078113	1.62058457350449	0.395714834959115	0.381636001616599	0.396820748739037	0.582828884808778	NA	NA	0.462358140265761	0.582895101840641	80.4214482119703
a6877	loss_cnaOV59	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.57055749382033	4.18225783834	0.38829965548033	1.37572489804506	0.92483331879321	0.397197072283824	0.282250947142203	0.419859068212433	0.582884943561622	NA	NA	0.210035055928294	0.617986084139776	80.4214482119703
a6878	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	151	QS11	ARFGAP	3	16	2.32630161961136	NA	4.37569811834952	3.65260723094028	0.723090887409239	1.90493870034825	1.38034598807794	0.49801912436232	0.379587483459205	0.523847566953924	0.583104454989024	NA	NA	0.0650840679690249	0.584760926150322	80.4400375432672
a6879	loss_cnaOV55	230	GSK429286A	ROCK2	7	25	2.99573227355399	2.32630161961136	5.42904927179382	5.56946082632535	-0.140411554531528	1.51166429675773	0.803589753715127	0.142300247269933	0.0928854077143234	0.174730394311752	0.583452492749152	NA	NA	0.304693893391064	0.819786132189102	80.4403896715252
a6880	loss_cnaOV1	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.80024571407418	3.29777293522213	-0.497527221147945	1.044726046732	1.0884643688475	0.458295602527179	0.476227449965715	0.457090958039116	0.583474943632008	NA	NA	0.0626437594522141	0.502109533551502	80.4403896715252
a6881	MLL2_mut	1028	VX-702	p38	3	28	0.693147180559945	NA	2.88601188941526	3.37421465008653	-0.488202760671271	0.952533885370686	0.919219086941865	0.529759578473472	0.512530596726522	0.531105987252141	0.583806588628294	NA	NA	0.518547261911613	0.472787098939743	80.4403896715252
a6882	gain_cnaOV96	272	AR-42	HDAC	4	26	1.63315443905142	NA	0.67670365771418	0.236389177571997	0.440314480142182	0.684860205217733	1.94682839238132	0.237598314567584	0.642926069857126	0.226170155451451	0.583838947070145	NA	NA	0.486559147184232	0.4064679080746	80.4403896715252
a6883	gain_cnaOV4_(KRAS)	1170	CCT018159	HSP90	7	26	2.30258509299405	NA	3.92719170426611	3.63243496953181	0.294756734734297	1.22386907432579	1.22891365046099	0.240041858069313	0.240840087324433	0.239851461185842	0.58388039158428	NA	NA	0.198623190713356	0.585058592877022	80.4403896715252
a6884	PIK3CA_mut	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.31842742573083	2.41456303121329	-0.0961356054824649	0.615604685560453	1.01595178202443	0.101250347889222	0.156164512287528	0.0946261497675618	0.583906224391761	NA	NA	0.735078943878384	0.759591810940498	80.4403896715252
a6885	TP53_mut	1033	Vismodegib	SMO	21	10	2.30258509299405	NA	4.95103964835435	4.82674104237537	0.124298605978979	0.945522358581369	0.652778840522689	0.143642188973684	0.131460250358831	0.190414575753485	0.583955378157839	NA	NA	0.154677089972698	0.673866051426715	80.4403896715252
a6886	gain_cnaOV18_(CCNE1)	219	AT-7519	CDK9	4	28	2.32630161961136	NA	2.05210682859673	1.41850783141304	0.633598997183697	2.0195918881652	1.66647168708797	0.371595363398234	0.313726253752842	0.380203877505331	0.584014366754689	NA	NA	0.316632650628613	0.584733539514234	80.4403896715252
a6887	loss_cnaOV36	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.79366248239161	4.25931340153353	0.534349080858074	1.83845534894049	1.2666304603344	0.407567070741498	0.290651106194132	0.421866596131755	0.584126773304508	NA	NA	0.371587216521726	0.667653135863371	80.4403896715252
a6888	loss_cnaOV33_(ZFHX3)	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.85401401293134	1.58025426142487	0.273759751506472	0.904867877993362	0.653676876030196	0.400839440851825	0.302541131323573	0.418799810036154	0.584287155368567	NA	NA	0.209543577359756	0.595297991633504	80.4403896715252
a6889	loss_cnaOV85	306	TG101348	JAK2	7	25	2.32630161961136	NA	2.61356456574458	2.8829969529436	-0.269432387199025	0.652291542368816	1.53513460624981	0.191942778680068	0.413055159692204	0.175510594381833	0.584405708292701	NA	NA	0.627826474007434	0.500269703971721	80.4403896715252
a6890	gain_cnaOV4_(KRAS)	1042	BIRB 0796	p38, JNK2	7	26	2.30258509299405	NA	4.23423932339228	4.44145297573999	-0.207213652347712	1.02640950398056	0.819133228607294	0.240068277413796	0.201882047607811	0.25296697180753	0.584483339824269	NA	NA	0.86965799123656	0.634646147802503	80.4403896715252
a6891	PIK3R1_mut	173	FH535	unknown 	3	15	3.46573590279973	NA	3.25780872536876	2.34462992036075	0.91317880500801	2.33531973906055	1.22879063441362	0.645247225265901	0.391029455082397	0.743152478081653	0.584597837819429	NA	NA	0.121866038191286	0.571370047951065	80.4403896715252
a6892	loss_cnaOV54	1026	17-AAG	HSP90	11	22	0	NA	0.0714529584333737	-0.83197471665176	0.903427675085134	2.40340563329232	2.20897612898238	0.397370834594225	0.375894798019412	0.408980279701492	0.584615917460379	NA	NA	0.0615437881234158	0.309230203354254	80.4403896715252
a6893	RB1_mut	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.58557443385074	4.48014335646059	0.105431077390146	0.404719778115006	0.721272264070533	0.149515618292514	0.260503892053891	0.14617375801357	0.584654636605196	NA	NA	0.081766225653631	0.717326109468401	80.4403896715252
a6894	loss_cnaOV52, loss_cnaOV53	274	PXD101, Belinostat	HDAC	8	22	2.99573227355399	NA	0.39030664388543	1.02365454225447	-0.633347898369035	1.40992723006709	2.25257254591124	0.305337451994297	0.449206090117785	0.281166482082301	0.584960784210586	NA	NA	0.416512545866015	0.370980126276166	80.4403896715252
a6895	loss_cnaOV59	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.78252327127966	3.52318087788368	0.259342393395979	1.25545634762079	0.925654249901484	0.26910365377223	0.206572210883681	0.2801719901611	0.585034346412571	NA	NA	0.72875994420169	0.71381769226333	80.4403896715252
a6896	gain_cnaOV94	1038	NU-7441	PRKDC (DNAPK)	7	26	0.693147180559945	NA	2.79155746354646	2.46852190213818	0.323035561408278	1.21461631379936	0.986720180724619	0.312185931548798	0.265956876865758	0.327383150480463	0.585107314093611	NA	NA	0.39563515537508	0.534331579113064	80.4403896715252
a6897	KRAS_mut	1373	Dabrafenib	BRAF	6	26	2.30258509299405	NA	3.21283607466006	3.74632424090464	-0.533488166244581	1.6808691264054	2.09588124620399	0.26246517204821	0.317388283158883	0.254541218502156	0.5852098676067	NA	NA	0.747678561468758	0.521537514185973	80.4403896715252
a6898	loss_cnaOV39	193	GW-2580	CSF1R (cFMS)	9	23	2.99573227355399	NA	5.87050411383682	5.67011488470172	0.200389229135103	0.737211757601147	0.544937137125057	0.332738267772191	0.27182044652565	0.367729074572351	0.585365557896336	NA	NA	0.192832980153263	0.473922589920445	80.4403896715252
a6899	loss_cnaOV41	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.46057598919683	2.12323928918218	0.337336700014651	0.825618983198913	1.35251227778364	0.257925004171123	0.408586414410699	0.249414889281039	0.585478759224419	NA	NA	0.686874548600613	0.516315758801771	80.4403896715252
a6900	loss_cnaOV42	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.46057598919683	2.12323928918218	0.337336700014651	0.825618983198913	1.35251227778364	0.257925004171123	0.408586414410699	0.249414889281039	0.585478759224419	NA	NA	0.686874548600613	0.516315758801771	80.4403896715252
a6901	KRAS_mut	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	1.14801693557037	1.65380759445606	-0.505790658885689	0.563133750674946	1.10639987936374	0.482156328176799	0.898171452660175	0.457149958454946	0.58549762910234	NA	NA	0.287718503782182	0.21160439470824	80.4403896715252
a6902	loss_cnaOV55	1149	TW 37	BCL2, BCL2L1	8	25	1.6094379124341	NA	-0.458450669266003	-0.830613779505921	0.372163110239918	0.952209354326651	0.905791818380601	0.406079382564954	0.39084168680856	0.410870470110098	0.585550570155689	NA	NA	0.0421492023004601	0.350585429392753	80.4403896715252
a6903	gain_cnaOV48_(SOX17)	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	1.8487854846995	2.36209240529351	-0.513306920594003	0.37102623487651	1.49547819110035	0.354507984734533	1.38347877412186	0.343239322143721	0.5856392442921	NA	NA	0.821141729350402	0.169094633279855	80.4403896715252
a6904	loss_cnaOV1	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	3.17735719659922	2.8771814552667	0.300175741332519	1.31925115858848	1.25002226296648	0.239230300791453	0.227534946153612	0.240136316148609	0.585812014901599	NA	NA	0.232116138434031	0.73711840421027	80.4403896715252
a6905	loss_cnaOV40	1006	Cytarabine	DNA synthesis	7	24	0.693147180559945	NA	-0.309766890853704	-0.053425835546696	-0.256341055307008	1.46069957999465	1.20944817109402	0.202556214007651	0.175491975775024	0.211948772534115	0.585856761115429	NA	NA	0.767400305355863	0.682130578793388	80.4403896715252
a6906	loss_cnaOV39	1018	ABT-888	PARP1, PARP2	10	21	1.6094379124341	NA	4.48623591975471	4.21070340243753	0.275532517317172	0.951596926622101	0.716711500029178	0.345690703504614	0.289547506521731	0.384439927789571	0.585947066525607	NA	NA	0.225635899868134	0.430078044257918	80.4403896715252
a6907	gain_cnaOV4_(KRAS)	262	VX-11e	ERK	8	24	1.63315443905142	NA	2.66899757751984	2.92270425722356	-0.253706679703726	1.16101801622918	1.11231694243174	0.225743935487376	0.218520880948711	0.228088479124551	0.586045843778986	NA	NA	0.39130838398639	0.598838908738924	80.4403896715252
a6908	SMAD4_mut	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.602633991736345	-1.2636166629601	0.660982671223759	1.27298202106451	1.32943455849388	0.499170615368795	0.519239596699901	0.49719082974087	0.586067293222804	NA	NA	0.0496174648720106	0.471725639759401	80.4403896715252
a6909	gain_cnaOV18_(CCNE1)	152	CP466722	ATM	4	28	2.77258872223978	NA	2.89008838198566	2.61217787116002	0.277910510825633	0.74659221108669	0.822355923990103	0.340954114035214	0.372238695634294	0.337944316710458	0.586136071407817	NA	NA	0.556367107551273	0.528667306044958	80.4403896715252
a6910	loss_cnaOV20	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.23223646421371	4.46802497640765	-0.235788512193939	1.06757579361194	0.673944356251216	0.319215638002714	0.220863486793939	0.349863471675172	0.586145786059157	NA	NA	0.524826768911949	0.65538529002492	80.4403896715252
a6911	gain_cnaOV26	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	-0.369271205029645	-0.606898501132377	0.237627296102732	1.12801321502939	1.96649782733535	0.125909417546609	0.210660028567609	0.120837812683842	0.586226306271638	NA	NA	0.0430132693622053	0.78323594118591	80.4403896715252
a6912	loss_cnaOV102	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.4740395563045	5.16149864174987	0.312540914554631	0.808981298561402	0.76928667987078	0.404847585514232	0.386338862357409	0.406273659394609	0.5863492353028	NA	NA	0.334156203316107	0.578195229786824	80.4403896715252
a6913	gain_cnaOV72_(ASXL1)	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.56945598042163	4.47764249196707	0.0918134884545578	0.821623099234602	0.663452108299744	0.134718880324468	0.111746479060884	0.13838751479719	0.586394386416225	NA	NA	0.0536827090821285	0.842518722738878	80.4403896715252
a6914	loss_cnaOV1	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.76334067093643	4.87006973349391	-0.106729062557478	0.217980187742833	0.643979156379363	0.170852999796069	0.489627354039138	0.165733722124703	0.58647825717959	NA	NA	0.0499016863755934	0.558577892939077	80.4403896715252
a6915	loss_cnaOV42	308	XL-880	MET	4	28	1.63315443905142	NA	-0.0551109159202709	0.297128303083957	-0.352239219004228	0.610452644385958	1.00388735218973	0.362483477729265	0.577013175786204	0.350875243358635	0.586697954657597	NA	NA	0.368838137682936	0.366962686370598	80.4403896715252
a6916	gain_cnaOV19	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.62672042081345	3.05183635189685	-0.425115931083401	0.856480775675723	1.0976974512598	0.39243088570667	0.49635198262098	0.387279692228042	0.586744057684172	NA	NA	0.435059774695545	0.489946205381594	80.4403896715252
a6917	loss_cnaOV38	163	JQ1	BRD4	4	15	0.940007258491471	NA	0.467449312766195	-0.012539080352018	0.479988393118213	2.47990734251296	1.722093067796	0.255560884578343	0.19355093833136	0.278723840246636	0.586929353694795	NA	NA	0.582702558245372	0.734900594151874	80.4403896715252
a6918	gain_cnaOV4_(KRAS)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	2.30258509299405	NA	2.47498326644398	2.10749417048024	0.367489095963742	1.06419556634208	1.34024679435065	0.281461645582857	0.345321017664921	0.274195094151887	0.586941532221283	NA	NA	0.686886988301591	0.521684768936356	80.4403896715252
a6919	PIK3R1_mut	151	QS11	ARFGAP	3	16	2.32630161961136	NA	3.68607987880718	3.78191065085447	-0.0958307720472864	2.21149903769486	1.35041136123367	0.0648386727127875	0.0433329476585144	0.0709641334472633	0.586996180047745	NA	NA	0.0651321633420095	0.948010440680849	80.4403896715252
a6920	SMAD4_mut	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.668323704678215	0.351633853235345	0.31668985144287	1.04706433185045	0.903172027417171	0.346554786604548	0.302455008550613	0.350641784542993	0.58700384935152	NA	NA	0.909762278977738	0.657839059454468	80.4403896715252
a6921	loss_cnaOV54	176	IPA-3	PAK1, PAK2, PAK3	6	13	3.46573590279973	NA	4.67983121584502	4.79799223151923	-0.118161015674211	1.693295940019	1.54524479075624	0.0743047891152717	0.0697816683319309	0.0764675062365899	0.58701067016155	NA	NA	0.122324253529861	0.887685515698236	80.4403896715252
a6922	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.0944417033746784	-0.641798785690336	0.547357082315658	1.45409853382873	1.49832786189933	0.366568352562095	0.376423653268141	0.365311956237543	0.587083055694642	NA	NA	0.909383446570593	0.595374546335625	80.4403896715252
a6923	gain_cnaOV95_(MECOM)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	9	23	2.32630161961136	NA	5.06992456205971	5.17081439171652	-0.100889829656815	0.554358852573241	0.602105614626571	0.171071840526186	0.181993719751207	0.167561682213157	0.587222232209849	NA	NA	0.0119762785300937	0.657665388195606	80.4403896715252
a6924	gain_cnaOV96	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	3.55177512849197	3.17005578437171	0.381719344120263	1.00847779482189	1.26385571700784	0.309619607903339	0.378510410521907	0.302027627824462	0.58744285850566	NA	NA	0.60135287883594	0.482058364688662	80.4403896715252
a6925	SMAD4_mut	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.10263914743761	1.5385768672979	-0.435937719860296	0.977474992527464	1.75454698446006	0.254378045963717	0.445983501565691	0.248461696222088	0.587548725773899	NA	NA	0.316679370208554	0.544717242521538	80.4403896715252
a6926	loss_cnaOV41	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-1.40462138318486	-2.12191151429202	0.717290131107169	0.594677081987726	1.62884992485763	0.461542680387257	1.20618425164394	0.440366003129396	0.587773151055149	NA	NA	0.0380616945474734	0.123407474018042	80.4403896715252
a6927	loss_cnaOV42	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-1.40462138318486	-2.12191151429202	0.717290131107169	0.594677081987726	1.62884992485763	0.461542680387257	1.20618425164394	0.440366003129396	0.587773151055149	NA	NA	0.0380616945474734	0.123407474018042	80.4403896715252
a6928	NF1_mut	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	3.62023407687416	3.87187849108449	-0.251644414210327	1.17436260511584	0.827978257074816	0.290058366718385	0.214281698952348	0.303926355626013	0.587828975525503	NA	NA	0.923832325906395	0.703076640513526	80.4403896715252
a6929	loss_cnaOV83	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	2.88414304328229	3.31909026100936	-0.434947217727073	0.982494756514042	1.09842079553645	0.401361031204956	0.442696731807806	0.395975039342417	0.587868892711911	NA	NA	0.0626739761700428	0.406635376248111	80.4403896715252
a6930	PTEN_mut	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	2.65457916077812	4.07710221635574	-1.42252305557762	1.32286828105256	1.44758858006678	0.990492735754366	1.07533234861884	0.982684635099841	0.588025043785536	NA	NA	0.0700855893337954	0.192285691951234	80.4403896715252
a6931	loss_cnaOV35	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	2.67624760494768	1.92443171455993	0.751815890387748	3.59612328207852	1.59788883677504	0.378899037990121	0.209062880055994	0.470505753019159	0.588077822935483	NA	NA	0.132888501207761	0.6683949291486	80.4403896715252
a6932	BRCA1_mut	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	2.60443441311896	2.34803491941337	0.256399493705585	1.11426734030886	1.33452261766748	0.1950071295896	0.230105904059356	0.192128248941728	0.588362197117253	NA	NA	0.110433584988075	0.6943584552701	80.4403896715252
a6933	RB1_mut	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.70035487954002	2.25540939675871	0.444945482781312	1.04146127122506	1.27471507097978	0.353126952245663	0.427231904896402	0.349054853834367	0.588381496110648	NA	NA	0.844708564588202	0.546667598576948	80.4403896715252
a6934	loss_cnaOV84	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	-0.510850473676925	-0.590281233201596	0.0794307595246713	2.15028047938656	1.80119867881872	0.0420458182956046	0.0369397203230583	0.0440988328820917	0.588451010466394	NA	NA	0.0430339923331593	0.943469015442052	80.4403896715252
a6935	loss_cnaOV39	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	2.53977383551798	2.3487280265325	0.191045808985487	1.15314780829331	0.940564767601611	0.192067577848781	0.16567330537465	0.203118185547863	0.588504933769825	NA	NA	0.411112055865664	0.750420425990548	80.4403896715252
a6936	loss_cnaOV81_(RB1)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	4	28	2.32630161961136	NA	5.37436549672825	5.10930678861087	0.265058708117381	0.372940008813828	0.60359694480328	0.453370249066922	0.710727467831691	0.439131957839459	0.588575828129067	NA	NA	0.0119791376229766	0.274132639361282	80.4403896715252
a6937	PIK3CA_mut	163	JQ1	BRD4	5	14	0.940007258491471	NA	-0.00689580055886093	0.122585003469915	-0.129480804028776	1.92868649391146	1.87605837489042	0.0685601118691922	0.0671341892202415	0.0690174707577204	0.588693705645975	NA	NA	0.582735973264167	0.900432328265064	80.4403896715252
a6938	loss_cnaOV54	203	BMS-345541	IKBKB	10	22	2.77258872223978	NA	3.25365492690431	3.28643452581383	-0.0327795989095208	1.13976528103546	1.00871066845558	0.0312262073122331	0.0287599556285316	0.0324965323899162	0.588800176826547	NA	NA	0.0923049849089056	0.938734954338394	80.4403896715252
a6939	gain_cnaOV94	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	1.97654546359022	2.38636636334794	-0.409820899757721	0.86321294975366	1.52297505159714	0.290242276879514	0.474762223938686	0.269092326448777	0.588801628633627	NA	NA	0.530439170082982	0.375179664098923	80.4403896715252
a6940	loss_cnaOV81_(RB1)	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	-1.55122713347042	-1.28399504384198	-0.267232089628443	1.70404217034283	1.90414336247253	0.141760969959012	0.156822462659289	0.140342421109218	0.588823731157633	NA	NA	0.0744616536624539	0.786491401379128	80.4403896715252
a6941	loss_cnaOV39	269	NSC-207895	MDM4	9	22	2.99573227355399	NA	3.68502865775523	3.96676334847698	-0.281734690721749	1.97903011508339	1.4273876382497	0.176228296771299	0.142359981576065	0.197377841289994	0.588824776467062	NA	NA	0.715942187684829	0.705202513655722	80.4403896715252
a6942	loss_cnaOV81_(RB1)	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.93835715435243	2.36840845233539	0.569948702017034	1.33421142419156	1.47036668132133	0.391092727895046	0.42718019924195	0.387623515451844	0.588911575738187	NA	NA	0.240681486698878	0.473232739517812	80.4403896715252
a6943	PIK3R1_mut	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.53283290217272	6.72854342809684	-0.195710525924119	2.20597615134889	1.41992583512213	0.127626741267453	0.0887183326095557	0.137831512803825	0.588947896356392	NA	NA	0.337997007702788	0.894207566160803	80.4403896715252
a6944	gain_cnaOV19	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	2.73220718237961	2.3916681299922	0.340539052387416	0.341470641600425	0.898219483904407	0.399777799482491	0.997271832188436	0.379126770783407	0.589023163156269	NA	NA	0.622628583311461	0.285117330549627	80.4403896715252
a6945	loss_cnaOV83	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	2.88281965746516	2.17725271052567	0.705566946939494	1.99452335339753	1.75326686136337	0.395003704469396	0.353752161255775	0.402429865349097	0.589073034394266	NA	NA	0.110950243025172	0.490703672281233	80.4403896715252
a6946	loss_cnaOV70	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	4.17401145285079	3.64705389263792	0.526957560212876	1.01753079835203	1.23726559329299	0.43042247044694	0.517878732581189	0.425904965812856	0.589156504261835	NA	NA	0.198684900765334	0.471654562767041	80.4403896715252
a6947	gain_cnaOV94	173	FH535	unknown 	3	15	3.46573590279973	NA	2.70417390012618	2.45535688540927	0.248817014716914	1.28984937226052	1.47959810527639	0.170746407240847	0.192903931317849	0.168165269899717	0.589233095177869	NA	NA	0.12195280209131	0.784730817465143	80.4403896715252
a6948	loss_cnaOV84	257	NPK76-II-72-1	PLK3	6	26	2.32630161961136	NA	3.02688726813386	3.27650223891126	-0.249614970777407	1.31465026181071	1.22095305903694	0.201780454353293	0.189871768962799	0.204442725238182	0.589315906449279	NA	NA	0.601371554130255	0.683550081250254	80.4403896715252
a6949	loss_cnaOV42	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.29690345576995	4.42518535480751	-0.128281899037559	0.555836160949136	0.643971418691095	0.201793748606376	0.230790848185385	0.199204336270543	0.589414735736173	NA	NA	0.271719063351925	0.692979884992709	80.4403896715252
a6950	PIK3R1_mut	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.19582053236786	4.5876434700192	-0.391822937651339	0.847635418767064	1.00444190619272	0.39754293225373	0.462254088227305	0.390090193604646	0.589457213532763	NA	NA	0.326077250840852	0.389921207814395	80.4403896715252
a6951	loss_cnaOV56	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.33234391203408	2.54671685411441	-0.214372942080324	0.611805578848633	1.07171133565214	0.205025579250035	0.350393898799937	0.200028622399406	0.58947480725971	NA	NA	0.19625746942155	0.631089128870929	80.4403896715252
a6952	gain_cnaOV51_(MYC)	1018	ABT-888	PARP1, PARP2	8	23	1.6094379124341	NA	4.50523608739017	4.2280539978093	0.277182089580877	0.684304725256109	0.831310270583569	0.347211727369897	0.405056518464253	0.333427962325425	0.589571955854361	NA	NA	0.22568276439669	0.366645315445787	80.4403896715252
a6953	loss_cnaOV81_(RB1)	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.64913935618046	3.22291255043663	0.426226805743833	1.22561607641599	1.01697018994428	0.409943584604248	0.347765351601968	0.419114355522246	0.589687037350014	NA	NA	0.0923125373535671	0.54681839680108	80.4403896715252
a6954	loss_cnaOV38	1248	FK866	NAMPT	8	24	0	NA	-0.865572252733262	-1.98928624807197	1.12371399533871	3.93444600790049	2.24576489026787	0.410908401771019	0.285609204722153	0.500370274826353	0.589775096429653	NA	NA	0.0448234509004402	0.463547310331823	80.4403896715252
a6955	loss_cnaOV40	1011	ABT-263	BCL2, BCL2L1, BCL2L2	8	25	0.693147180559945	NA	1.86082318654643	1.69841734074083	0.162405845805606	1.487920248907	1.77358685373195	0.0947940136778043	0.109149563577017	0.0915691529083418	0.589804251115572	NA	NA	0.22981513111293	0.801706477162452	80.4403896715252
a6956	loss_cnaOV87, loss_cnaOV88	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	3.51671635461425	2.77457693744338	0.74213941717087	2.60045772121915	1.78977628571758	0.400101538990999	0.285387995780581	0.414654849934678	0.589857414692841	NA	NA	0.346919417819241	0.673152935352219	80.4403896715252
a6957	gain_cnaOV72_(ASXL1)	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.13106873286399	4.30648341009021	-0.175414677226219	0.275946395547768	0.864936715737184	0.212940627021311	0.635683886640417	0.202806371882032	0.589867078161831	NA	NA	0.317482853837937	0.430259133092948	80.4403896715252
a6958	loss_cnaOV87, loss_cnaOV88	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	2.07602834376328	1.47467583223903	0.601352511524251	1.3292274763518	1.9618801836322	0.312199712566398	0.452407524086639	0.30651846965033	0.589920113736	NA	NA	0.782863912308199	0.530183545201503	80.4403896715252
a6959	loss_cnaOV82	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.8992978930956	5.5014473062553	0.397850586840306	1.2035882436183	0.963423234450987	0.405446766176078	0.330553732931342	0.412955150564771	0.589974071749538	NA	NA	0.304779689134834	0.629013981127281	80.4403896715252
a6960	gain_cnaOV26	1026	17-AAG	HSP90	3	30	0	NA	0.440959219727741	-0.628011296091828	1.06897051581957	2.80423330102054	2.25431468562761	0.466031057255119	0.381198852260453	0.474188684762953	0.590064506754211	NA	NA	0.0615794607432181	0.580919456659107	80.4411607908347
a6961	gain_cnaOV19	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.8667351870519	4.40861759899839	0.458117588053517	0.358119148716752	1.01268503910315	0.466179427423313	1.27923231610231	0.452379140960979	0.590290211897654	NA	NA	0.0314954605562227	0.149445100027863	80.4462024074334
a6962	loss_cnaOV36	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	2.08771751886041	1.70279554847703	0.384921970383376	2.1242185383485	1.67870179788901	0.224975687792275	0.181206388812819	0.229297407596406	0.590369859640375	NA	NA	0.229821935843296	0.78657201731606	80.4462024074334
a6963	loss_cnaOV36	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	3.92879070091945	3.5244809157864	0.404309785133053	2.10042479374886	0.770852359857992	0.441004741816416	0.192489531801535	0.524497045332437	0.590394746723317	NA	NA	0.143375054674733	0.771252511152749	80.4462024074334
a6964	loss_cnaOV43_(NF1)	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	5.07156609430783	4.82089680787383	0.250669286433996	0.518266417941115	0.632405988913731	0.405347584274154	0.483668780681979	0.396373992068868	0.590572494242067	NA	NA	0.0499258260408732	0.372880258897046	80.4462024074334
a6965	loss_cnaOV43_(NF1)	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.99821436777273	3.27256703635675	-0.274352668584023	0.956489753944178	1.27454972825507	0.221810910598189	0.286832835848689	0.215254581678525	0.590635082355954	NA	NA	0.601384633997766	0.595400949028366	80.4462024074334
a6966	RB1_mut	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.54728649024361	2.25784382371045	0.28944266653316	1.42939654796723	1.82611469937032	0.160520050152623	0.202492909993928	0.158501909344996	0.590761030764854	NA	NA	0.110965532397658	0.768568779964563	80.4462024074334
a6967	loss_cnaOV20	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.57667119312743	4.2585350324528	0.318136160674634	0.823111214433619	0.797893411611182	0.39740245636815	0.38650446634182	0.398720124824972	0.590766117947751	NA	NA	0.225698075175128	0.510126383739117	80.4462024074334
a6968	SMARCA4_mut	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	0.538885764486345	0.968374920801971	-0.429489156315626	0.608215718171328	1.31109986143366	0.337165840016011	0.706146098306923	0.327579285872235	0.590844042605087	NA	NA	0.95753113392366	0.370885070473434	80.4462024074334
a6969	gain_cnaOV96	346	THZ-2-102-1	CDK7	5	27	0.916290731874155	2.99573227355399	-1.60184710032521	-0.958968425869321	-0.642878674455888	0.554000316601358	2.11022360356688	0.32552481070535	1.16043015715185	0.304649551530578	0.590864551073982	NA	NA	0.444161741692783	0.188324092144807	80.4462024074334
a6970	gain_cnaOV49	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.4750625542896	4.09037548653623	-0.615312932246625	2.16825280682499	1.4388340498254	0.410605865541284	0.283782836719874	0.427646907801003	0.591147868114139	NA	NA	0.330349135881063	0.674579819766707	80.4729149935772
a6971	loss_cnaOV38	1049	PD-173074	FGFR1, FGFR3	8	25	0.693147180559945	NA	3.27175092226769	2.89523279563891	0.376518126628782	1.09615568011982	0.970949831760682	0.376295166515368	0.343489646094455	0.387783296636469	0.591230376466785	NA	NA	0.0880869642028632	0.404028949545867	80.4729149935772
a6972	loss_cnaOV35	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	4.81074485840585	4.86919703674457	-0.0584521783387162	0.601508517976609	0.628679707944348	0.0935047661412382	0.0971759777157291	0.0929760855966588	0.59144507908363	NA	NA	0.0499309276092773	0.849736078117898	80.4838582226681
a6973	gain_cnaOV48_(SOX17)	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.51897257437788	3.96280949027523	-0.443836915897352	1.27088612623436	1.22068942213444	0.362547482334678	0.349234212834193	0.363595283001044	0.591694369660427	NA	NA	0.69913825525203	0.613244464183792	80.4838582226681
a6974	loss_cnaOV55	1066	AZD6482	PI3Kbeta	8	25	1.6094379124341	NA	2.32674105064769	2.39587287641128	-0.0691318257635865	1.43908076057922	1.27959697372637	0.0524800098638178	0.0480388784683365	0.0540262498138491	0.59172214626049	NA	NA	0.110463934654023	0.905618076403497	80.4838582226681
a6975	loss_cnaOV70	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.62262315155168	-4.10661040557729	0.483987254025614	2.40769944268422	1.44431619135999	0.316258724428911	0.201016474666805	0.335097852479161	0.591773960438988	NA	NA	0.864266471946125	0.763059315067988	80.4838582226681
a6976	loss_cnaOV102	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	1.3484268327482	0.799910095645817	0.548516737102386	1.45800528077661	2.1282024927059	0.262765119029126	0.376210391234124	0.2577370992574	0.591811204271353	NA	NA	0.416605956984715	0.598509345377282	80.4838582226681
a6977	loss_cnaOV58	1016	Temsirolimus	MTOR	5	26	-1.6094379124341	NA	-2.09800581012332	-2.01615643723106	-0.0818493728922673	1.4130434345679	1.59775448795985	0.0520151914734782	0.0579241733763804	0.0512277533933137	0.591830520401805	NA	NA	0.0380822497968603	0.911317782996164	80.4838582226681
a6978	gain_cnaOV4_(KRAS)	1016	Temsirolimus	MTOR	5	26	-1.6094379124341	NA	-1.76285449068568	-2.08060861404599	0.317754123360311	1.23254376382863	1.61660479556237	0.202490568183755	0.25780352202122	0.196556464655155	0.591904546492217	NA	NA	0.0380826222115098	0.632685246830803	80.4838582226681
a6979	ARID1A_mut	303	PIK-93	PI4K, PI3K	8	24	2.99573227355399	NA	3.05330833708112	2.85599446232846	0.197313874752664	1.31613746664671	1.23567018453155	0.157233802691496	0.149918895064499	0.159681666857947	0.591989982980456	NA	NA	0.232193512065882	0.716132609171228	80.4839414413399
a6980	loss_cnaOV1	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.90131468446839	2.34102084623067	-0.439706161762277	1.24165285526454	1.2615495857338	0.348921226180323	0.354129706945018	0.34854449379928	0.592277350719456	NA	NA	0.844725489089657	0.609428548879541	80.4955200541515
a6981	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	3.30405160110222	3.76037641261096	-0.456324811508739	3.3847340202556	1.38136144646926	0.224377446607663	0.134818514180999	0.33034425035902	0.592398586347231	NA	NA	0.747726667305238	0.72040685571807	80.4955200541515
a6982	loss_cnaOV41	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.95731897149397	4.76502472201727	0.192294249476699	0.797808509084112	0.643110708950804	0.288809447464045	0.241028075392996	0.299006449123535	0.592464932886607	NA	NA	0.762397597268341	0.632248985260663	80.4955200541515
a6983	loss_cnaOV41	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	2.39909922263695	1.81135275377312	0.587746468863827	0.908261862332828	1.42993877358981	0.4278245807557	0.647111249782335	0.411029115175549	0.592805005328716	NA	NA	0.0344797982337778	0.262367092158027	80.4955200541515
a6984	gain_cnaOV48_(SOX17)	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.24613310996203	3.5752250412592	-0.329091931297161	0.744055401417852	0.916685763305195	0.363155652570359	0.442294929477095	0.359001900619237	0.592826659747308	NA	NA	0.66369154332333	0.53343807746356	80.4955200541515
a6985	ARID1A_mut	1527	GDC0941 (rescreen)	PI3K	9	22	1.38629436111989	NA	0.29991529238629	0.415976426052168	-0.116061133665878	1.12678869796182	0.823627929880861	0.126521863939887	0.103001684233977	0.140914519111399	0.592854196577162	NA	NA	0.909777201125217	0.784436971825352	80.4955200541515
a6986	loss_cnaOV35	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	4.65695845054404	5.10202637871347	-0.44506792816943	1.76973627270849	1.08885982703044	0.374205145385457	0.25148827824401	0.408746761631596	0.592877586259453	NA	NA	0.801228103828008	0.710053159996997	80.4955200541515
a6987	gain_cnaOV72_(ASXL1)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	1.51445387856965	1.1059845972067	0.408469281362945	2.00701721074806	1.40615646927023	0.272804296186368	0.203520567325229	0.290486364988196	0.592893589677107	NA	NA	0.813312199132237	0.6817809501699	80.4955200541515
a6988	gain_cnaOV19	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.65103968780747	2.36689478265606	0.284144905151406	1.07010363360622	0.937062258203983	0.300201593691707	0.265530268497311	0.30322948412842	0.592925256559503	NA	NA	0.735142150261041	0.695773681340084	80.4955200541515
a6989	gain_cnaOV51_(MYC)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	3.72589541703374	3.37091763762682	0.354977779406917	0.984971393356211	1.15128002029018	0.31854178349009	0.360393999055504	0.308333136292459	0.593055643495937	NA	NA	0.773545580834401	0.526847631800588	80.4955200541515
a6990	gain_cnaOV94	288	KIN001-055	JAK3, MNK1	7	25	2.32630161961136	NA	4.01224019153533	3.74183706732144	0.270403124213897	1.02372164990712	1.03562173006182	0.261700869355806	0.264137350458917	0.261102211709825	0.593172917662129	NA	NA	0.717551970936347	0.55195273951473	80.4955200541515
a6991	PTEN_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	2.67705385032934	1.60823460722672	1.06881924310262	1.07254872741678	1.72880165947357	0.637508140750946	0.996522783330188	0.618242837311994	0.59322440839469	NA	NA	0.229856075904825	0.14298828342291	80.4955200541515
a6992	loss_cnaOV34	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	4.10734294259509	4.34370267072162	-0.236359728126534	1.63353221436625	1.26423836653836	0.179370542101429	0.144692419315546	0.186958199009349	0.593225384781057	NA	NA	0.371701365993996	0.771108974011433	80.4955200541515
a6993	loss_cnaOV84	1170	CCT018159	HSP90	6	27	2.30258509299405	NA	4.04962608557517	3.61614424534218	0.433481840232985	1.61889095677583	1.12993408795582	0.354701717723796	0.267764693118247	0.383634625110924	0.593262861515433	NA	NA	0.198732158136436	0.555730234460944	80.4955200541515
a6994	gain_cnaOV72_(ASXL1)	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-3.15784777081792	-2.65335615031435	-0.504491620503572	1.48760631628872	1.81318242169528	0.284504418519256	0.339129791921143	0.278235446399202	0.59343633462534	NA	NA	0.696655528348863	0.525257271685654	80.5074392874315
a6995	loss_cnaOV59	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.36085418993186	4.5322341932584	-0.17138000332654	0.705375604831059	0.593810544449203	0.284735511617709	0.24296275934803	0.28861057609798	0.593520406347704	NA	NA	0.615526184157699	0.719284627233683	80.5074392874315
a6996	loss_cnaOV38	301	PHA-793887	CDK-pan	8	24	2.32630161961136	NA	3.32412191946086	2.90507869987368	0.419043219587183	1.8216193143892	1.5606970875903	0.257820418516855	0.23003885404437	0.268497470085103	0.593910912041107	NA	NA	0.663881276320246	0.571901018734422	80.5101621243466
a6997	loss_cnaOV34	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.51920141181118	2.33239764370483	0.186803768106343	0.696152133348318	0.899430679362732	0.213475497220294	0.268337564675502	0.207691123276669	0.593938009770868	NA	NA	0.608405119238856	0.616748511192821	80.5101621243466
a6998	loss_cnaOV21, loss_cnaOV22	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.50646501637017	4.11544771760675	0.391017298763417	0.524836153738523	1.05776974170938	0.378992670855186	0.745027368976233	0.369662019383846	0.593959608432657	NA	NA	0.530221744251366	0.338981638548289	80.5101621243466
a6999	SMARCA4_mut	308	XL-880	MET	3	29	1.63315443905142	NA	0.0689148033078267	0.272151876301594	-0.203237072993768	1.38981458357933	0.940878540795376	0.207969404552248	0.146233228083095	0.216007767402114	0.593968789926314	NA	NA	0.368932060892968	0.825794879878919	80.5101621243466
a7000	loss_cnaOV39	226	GSK1070916	AURKB	9	23	0.940007258491471	2.32630161961136	2.5093435886515	2.23751930042377	0.271824288227733	1.0983113628991	1.55919763656613	0.187376753958113	0.247492921779693	0.174336005810258	0.594176289555232	NA	NA	0.821182821597916	0.584680287856724	80.5101621243466
a7001	gain_cnaOV4_(KRAS)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	7	26	-2.30258509299405	NA	-0.0742166022051077	-0.402122435603293	0.327905833398185	1.85777667539852	1.28208928187801	0.232235885427154	0.176504440894568	0.255758969389297	0.594191422753461	NA	NA	0.88911765911686	0.672411737767003	80.5101621243466
a7002	PIK3R1_mut	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.22638107735504	3.28541494259897	-0.0590338652439319	0.871305731495277	1.07444110135592	0.0562425337451598	0.0677533305589783	0.0549437890726931	0.594247857350235	NA	NA	0.0923510170136593	0.897594317765414	80.5101621243466
a7003	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	2.30258509299405	NA	2.37435550746357	2.0945617697825	0.279793737681068	1.94468492055133	1.02393324064298	0.214075325773051	0.143876128582179	0.273253886655121	0.594256926318872	NA	NA	0.686948255432975	0.707222056112686	80.5101621243466
a7004	gain_cnaOV72_(ASXL1)	290	KIN001-260	IKK	4	27	2.99573227355399	NA	5.05278294191926	4.82024101071889	0.23254193120037	0.762365875733963	0.921093735616434	0.256678952698715	0.305026678924332	0.252462830012348	0.594304148714916	NA	NA	0.665802987167547	0.606982917221875	80.5101621243466
a7005	SMAD4_mut	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	1.96177805078436	1.68819439260439	0.273583658179966	1.70970127251159	1.59780448196254	0.169955104579759	0.1600183977041	0.171224740741702	0.594996577851012	NA	NA	0.0414949108291472	0.778981465208842	80.5777952125067
a7006	gain_cnaOV48_(SOX17)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.47966110079892	4.08989977482837	-0.610238674029441	2.16840674174086	1.43902730024451	0.407168661793274	0.281422605031897	0.424063305766161	0.595011890439769	NA	NA	0.330398948666381	0.677015697174468	80.5777952125067
a7007	loss_cnaOV55	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	3.19521816665705	3.35270758810787	-0.157489421450823	0.987084774625944	0.989320529396411	0.159252932411231	0.159550046256669	0.159189480831766	0.595105201994684	NA	NA	0.190931167447306	0.788810350411933	80.5777952125067
a7008	gain_cnaOV18_(CCNE1)	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.75782170845214	1.24590156090454	0.511920147547601	0.971307029738169	1.23955543989427	0.421195574743223	0.527042564167992	0.412986891164193	0.595205062858581	NA	NA	0.0979529617959646	0.390252761509619	80.5777952125067
a7009	loss_cnaOV52, loss_cnaOV53	224	AS605240	PI3Kgamma	8	24	2.99573227355399	2.32630161961136	3.04771786397337	3.4842288073887	-0.436510943415332	1.96848509248472	1.56959873974434	0.261194590730735	0.221749682068633	0.27810352567334	0.595228014732896	NA	NA	0.630240098368672	0.58125910832442	80.5777952125067
a7010	gain_cnaOV19	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.21747609895196	1.94866944314571	0.268806655806255	0.640669684595193	1.03825740538634	0.2695437416871	0.419571367694884	0.258901746726509	0.595389445505439	NA	NA	0.480534192269375	0.584665518645322	80.5807850912358
a7011	gain_cnaOV95_(MECOM)	1010	Gefitinib	EGFR	7	23	-0.693147180559945	NA	1.15565953995363	0.855354929366818	0.300304610586813	1.09466024250449	1.31870776339063	0.235714424686836	0.274335907093639	0.227726429557583	0.595419954036079	NA	NA	0.957536790974171	0.556916811886787	80.5807850912358
a7012	loss_cnaOV20	272	AR-42	HDAC	5	25	1.63315443905142	NA	-0.202141053937424	0.394545540696631	-0.596686594634054	1.08536513923228	1.94333452645204	0.323345380493652	0.549756550183761	0.307042656069838	0.595622993102773	NA	NA	0.486709204699791	0.359714232303438	80.5897433587298
a7013	gain_cnaOV94	1053	MK-2206	AKT1, AKT2	7	25	1.38629436111989	0.693147180559945	1.67080511147758	1.20883579035171	0.461969321125876	1.016839213962	1.25602014783383	0.381173486004151	0.454318947167531	0.367804069005266	0.595781883145241	NA	NA	0.0979579253126997	0.334716414662285	80.5897433587298
a7014	gain_cnaOV95_(MECOM)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	-1.38629436111989	0.693147180559945	-1.91595206904574	-2.19001545932629	0.274063390280556	1.38517394087763	1.27165173608679	0.211117809684518	0.197854855764116	0.215517647248233	0.595966453570024	NA	NA	0.608032677998187	0.629174629381374	80.5897433587298
a7015	loss_cnaOV52, loss_cnaOV53	179	5-Fluorouracil	DNA antimetabolite	8	23	3.46573590279973	NA	4.34426499761414	3.74895687406682	0.595308123547327	1.3274299887351	1.81293834379825	0.348454085194549	0.448466682687043	0.328366447531861	0.596068145131048	NA	NA	0.147853056462029	0.337254379834834	80.5897433587298
a7016	PIK3R1_mut	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	1.92697856214368	2.53459157304008	-0.607613010896409	1.12644402348469	1.4963760912398	0.418320579362698	0.539408082628677	0.406056348035459	0.596146576638739	NA	NA	0.240771705229733	0.330191809900046	80.5897433587298
a7017	gain_cnaOV49	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.2735403519189	2.98492394523077	0.288616406688126	1.19033664463838	1.07962459196349	0.265429506815769	0.242466203143571	0.267330337634516	0.596177014484493	NA	NA	0.435176591514115	0.72056459969098	80.5897433587298
a7018	ARID1A_mut	1025	SB 216763	GSK3A, GSK3B	6	17	2.30258509299405	NA	4.69394533332172	5.05384222166795	-0.359896888346238	0.683028887462357	0.8563539655609	0.439744726228526	0.526913129082074	0.420266505230125	0.596315490121197	NA	NA	0.454993170551828	0.32279483021605	80.5897433587298
a7019	loss_cnaOV40	238	CAL-101	PI3Kdelta	7	25	2.99573227355399	2.32630161961136	4.25651485640357	4.42382009829541	-0.167305241891846	0.798841113962656	1.03346324044093	0.168825915302287	0.20943494140146	0.161887946609948	0.596341749170253	NA	NA	0.512075976345488	0.655491518244333	80.5897433587298
a7020	loss_cnaOV54	1005	Cisplatin	DNA crosslinker	10	21	1.79175946922805	2.30258509299405	3.33758307233939	2.87403755429826	0.463545518041134	0.968294263535936	1.26588912427278	0.392309685344386	0.478723808967325	0.366181768334117	0.59640571815495	NA	NA	0.0890036704799999	0.272686237743922	80.5897433587298
a7021	loss_cnaOV70	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	1.67364674375604	2.07999841677891	-0.406351673022873	2.193063124587	1.98592775547318	0.203134786157727	0.185289547057337	0.204615536442842	0.596434211935039	NA	NA	0.132973169961893	0.783176454150893	80.5897433587298
a7022	KRAS_mut	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-3.42479717256005	-2.38075307687498	-1.04404409568507	0.583985110160667	2.10542407889969	0.525220823308295	1.78779232127653	0.495883041401661	0.596446025446928	NA	NA	0.3463017714995	0.118425051359581	80.5897433587298
a7023	loss_cnaOV56	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.23714076138559	3.68403228772448	-0.446891526338887	1.14458996781134	0.871024582907536	0.495378161512598	0.390438094782033	0.513064194867077	0.596626675816334	NA	NA	0.0603145526169175	0.574333013368946	80.5897433587298
a7024	loss_cnaOV40	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	-0.278650427586751	-0.00308848627170373	-0.275561941315047	1.00725151779485	0.954426065611718	0.28549059931542	0.273578084963652	0.288720049927002	0.596699885366724	NA	NA	0.54950965373424	0.533331444844147	80.5897433587298
a7025	gain_cnaOV94	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.79886845643749	1.56284384706237	0.236024609375111	0.737513971669928	0.6673134643072	0.346111676762244	0.320027305843019	0.35369376162693	0.596747869532566	NA	NA	0.20969464714214	0.464708223124654	80.5897433587298
a7026	SMARCA4_mut	272	AR-42	HDAC	3	27	1.63315443905142	NA	0.973338571645839	0.219737686399672	0.753600885246168	2.94248003161184	1.73186183221428	0.408484355401308	0.256110789928916	0.435139149803103	0.596760187305765	NA	NA	0.486723361861639	0.703069490196572	80.5897433587298
a7027	loss_cnaOV84	301	PHA-793887	CDK-pan	6	26	2.32630161961136	NA	2.7388466822694	3.07237630996303	-0.333529627693635	0.973904738639493	1.73227871863828	0.204548598393704	0.342466377316905	0.192538085300626	0.596882029585679	NA	NA	0.663906392219915	0.534278328694812	80.5947266772091
a7028	loss_cnaOV1	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.6495663013641	4.43148937675647	0.218076924607637	0.397025690387558	0.56690323145513	0.391385793873654	0.549276608258675	0.384681039915535	0.597059533387375	NA	NA	0.365535690128074	0.452388559586185	80.6072232732654
a7029	loss_cnaOV52, loss_cnaOV53	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	8	23	2.32630161961136	NA	2.00439529875104	2.39449776415103	-0.390102465399988	0.57157192014634	1.58885770606318	0.276260768702051	0.682508100293153	0.245523852709611	0.597530670854901	NA	NA	0.530539217356768	0.323133778035491	80.6593532774238
a7030	loss_cnaOV58	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.646062785833327	0.215956447270476	0.430106338562851	1.23569246277233	1.12162398412803	0.378286487112148	0.348069079905115	0.383467494141741	0.59794848502736	NA	NA	0.147361467033801	0.498538040460041	80.6783601633919
a7031	loss_cnaOV21, loss_cnaOV22	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.0532015652406	4.30118907675439	-0.247987511513785	0.203140425457175	0.930152196752809	0.27549826571202	1.22076888908586	0.266609606878872	0.597970510564729	NA	NA	0.522153876997836	0.253344652169255	80.6783601633919
a7032	gain_cnaOV95_(MECOM)	192	LFM-A13	BTK	5	14	2.77258872223978	NA	4.86742482995437	4.67424970374291	0.193175126211456	0.842169782714342	0.641726226462705	0.278303578050723	0.229377888136578	0.301024203539674	0.59801837641249	NA	NA	0.95702303255748	0.657800048333962	80.6783601633919
a7033	loss_cnaOV38	179	5-Fluorouracil	DNA antimetabolite	8	23	3.46573590279973	NA	4.34277876344191	3.74947382508324	0.593304938358669	2.06836454559582	1.57696632630383	0.347252564373497	0.286847373990237	0.376231837333702	0.598116815469561	NA	NA	0.1478751992051	0.476357403148274	80.6783601633919
a7034	PTEN_mut	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.61158042423713	4.36797003227714	0.243610391959994	0.423863345045807	0.89810904745256	0.282063750160459	0.574738048966387	0.271248121429109	0.598140048407695	NA	NA	0.869704440381717	0.394242572279817	80.6783601633919
a7035	loss_cnaOV39	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	10	23	-1.38629436111989	0.693147180559945	-1.90034887326927	-2.47125707943666	0.57090820616739	1.4078389038598	1.68047741562638	0.355462616197903	0.405520975874556	0.339729770158554	0.598181651571526	NA	NA	0.124845879733983	0.32540860579502	80.6783601633919
a7036	ARID1A_mut	312	AV-951	VEGFR	8	24	-2.05572501506252	NA	0.275781130041333	0.761202455153608	-0.485421325112274	0.661973653180453	0.557075734550798	0.832281378441332	0.73329402579705	0.871374025120116	0.598447014077817	NA	NA	0.015233874667347	0.0902211004305687	80.6866382636512
a7037	ARID1A_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	0.678507906664827	1.3552446999373	-0.676736793272471	0.827864003172678	1.73658232584642	0.430824265711082	0.817449231611675	0.389694622132368	0.598492437675303	NA	NA	0.535564902105735	0.272184088879916	80.6866382636512
a7038	gain_cnaOV95_(MECOM)	1371	PLX4720 (rescreen)	BRAF	8	25	2.30258509299405	NA	4.70330399745589	4.47226751370918	0.23103648374671	0.938568357715195	1.00572904456026	0.233143714230687	0.2461583984241	0.229720405308298	0.598498143017894	NA	NA	0.326189578147757	0.562125858019314	80.6866382636512
a7039	loss_cnaOV38	329	QL-XI-92	DDR1	8	24	2.32630161961136	NA	4.78383033689615	4.45028912282162	0.333541214074528	1.10176985709466	0.986615803243814	0.328723864389438	0.302732201218563	0.338065955337331	0.598770616390993	NA	NA	0.191993002097883	0.462875910718868	80.6978095938653
a7040	loss_cnaOV40	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-0.464523561547117	-0.5973396924679	0.132816130920783	2.48620862365319	1.73400404470661	0.0703236058041357	0.0534211528578906	0.076595052546867	0.598816961933872	NA	NA	0.0431285547091613	0.924989723830053	80.6978095938653
a7041	loss_cnaOV81_(RB1)	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.54719306063805	2.32973421599524	0.21745884464281	0.886576200846648	0.869986807207888	0.249476695041981	0.245279361700827	0.24995648536409	0.598892639991239	NA	NA	0.651047026633716	0.670182156158275	80.6978095938653
a7042	loss_cnaOV40	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	2.0437402319802	2.44233267445464	-0.398592442474437	2.57297801882826	1.40659416469571	0.229744941672399	0.154914826149956	0.28337416184338	0.598921206545035	NA	NA	0.645232230719131	0.81885987891537	80.6978095938653
a7043	PIK3CA_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	-0.0345987308646588	-0.760371141348834	0.725772410484175	2.56998752854842	1.57710057127459	0.390398266146462	0.282403086560542	0.460194120592838	0.599193124829884	NA	NA	0.0431319250685627	0.578491519340777	80.7224072328482
a7044	loss_cnaOV56	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	1.39028673657472	0.624341722405627	0.765945014169092	2.09412094482833	2.33348060645125	0.330391908971602	0.36575968358498	0.328241431298604	0.599300234244363	NA	NA	0.945920078145234	0.59976455629184	80.7224072328482
a7045	gain_cnaOV94	1047	Nutlin-3a	MDM2	7	26	2.07944154167984	1.38629436111989	3.64090218429409	3.77645391186743	-0.135551727573338	1.82283221546698	1.5057290755058	0.0862231500684066	0.0743632499048254	0.0900239822544461	0.599369554305012	NA	NA	0.165772459960495	0.860814034580872	80.7224072328482
a7046	loss_cnaOV39	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-2.89166534509126	-1.91550715584841	-0.976158189242844	3.80798697699835	2.18401550991766	0.367394121474429	0.256344938976735	0.446955703753058	0.599581918081539	NA	NA	0.418078423434395	0.611054526269235	80.7224072328482
a7047	loss_cnaOV16, loss_cnaOV17	1061	SB590885	BRAF	6	27	1.6094379124341	NA	4.12309957298343	3.88408210231683	0.239017470666598	1.57633235623182	1.2278641461273	0.185220373761274	0.151628855248498	0.19466116949539	0.599596456906564	NA	NA	0.573697396514491	0.738507705196953	80.7224072328482
a7048	gain_cnaOV19	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.31722551234558	2.5308464283872	-0.213620916041626	0.484264237334999	0.640551426714583	0.338362693998809	0.441124699228717	0.333495340315292	0.599667443887898	NA	NA	0.858316810430479	0.536259012318233	80.7224072328482
a7049	loss_cnaOV21, loss_cnaOV22	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.642086288669722	0.35444500495054	0.287641283719181	0.656477929926264	0.931004263570725	0.314458155370257	0.438158345630126	0.308958073528017	0.59969929533565	NA	NA	0.909794276396104	0.541529704101788	80.7224072328482
a7050	gain_cnaOV26	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	1.68301868939635	2.22481163446021	-0.541792945063858	3.10247423221675	1.19882799248127	0.349689327919921	0.174632536650189	0.451935514070276	0.599812577864725	NA	NA	0.947855630280233	0.792249938574952	80.7262034559522
a7051	loss_cnaOV1	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.42406049214698	3.97105075778207	0.45300973436491	0.882489230942765	1.06093711810189	0.43144419228801	0.513331742168636	0.426990183146182	0.600070537853548	NA	NA	0.105194830429069	0.475260645666973	80.749467359815
a7052	gain_cnaOV95_(MECOM)	273	CUDC-101	HDAC, EGFR	8	23	1.63315443905142	NA	-0.149149574071769	0.211021376451762	-0.36017095052353	1.01026461130883	1.78115161978053	0.221122581910557	0.356511498563647	0.202212403774985	0.600807818251968	NA	NA	0.46258296371983	0.491855977232837	80.825796332293
a7053	loss_cnaOV38	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-2.11837817703503	-2.38160944980934	0.263231272774301	0.668202074165176	0.775409170727741	0.347457162320606	0.393939622386193	0.339474025729218	0.600808128055337	NA	NA	0.675118892344531	0.527050813635798	80.825796332293
a7054	loss_cnaOV41	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.88593690858133	2.46979381395638	0.416143094624951	0.871127309115502	1.05562226036305	0.401130578200326	0.477706404414622	0.394215914395203	0.601183083185953	NA	NA	0.196404309403904	0.431937445707994	80.8315559830989
a7055	loss_cnaOV42	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.88593690858133	2.46979381395638	0.416143094624951	0.871127309115502	1.05562226036305	0.401130578200326	0.477706404414622	0.394215914395203	0.601183083185953	NA	NA	0.196404309403904	0.431937445707994	80.8315559830989
a7056	KRAS_mut	164	JQ12	HDAC	3	16	1.63315443905142	NA	1.35793083951226	1.87563597333172	-0.517705133819454	2.71094804326233	2.16385068839815	0.231617132185449	0.190968298011515	0.239251782294969	0.601298109036318	NA	NA	0.661259222399722	0.778765738821963	80.8315559830989
a7057	loss_cnaOV16, loss_cnaOV17	1023	GW 441756	NTRK1	6	25	0.693147180559945	NA	2.03588757455374	2.36148809202166	-0.325600517467911	1.7545785679592	1.1304918999016	0.258344054503862	0.185571922177658	0.288016674419562	0.601426608650543	NA	NA	0.844764338074847	0.679739119563821	80.8315559830989
a7058	loss_cnaOV57_(ZNRF3)	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.640726655152454	0.354590679970248	0.286135975182207	0.657715938568903	0.930986091332809	0.312797421904935	0.435044915902142	0.307347207274141	0.601559713663832	NA	NA	0.909798846628665	0.54414392319188	80.8315559830989
a7059	gain_cnaOV4_(KRAS)	1031	Elesclomol	HSP70	5	26	-1.6094379124341	NA	-4.39078520697899	-3.99611672215093	-0.394668484828054	1.20267602712479	1.57623816647105	0.257928966662788	0.328158602921169	0.250386326903666	0.601737548947832	NA	NA	0.864303585888162	0.545001381421905	80.8315559830989
a7060	gain_cnaOV4_(KRAS)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	7	26	1.6094379124341	NA	2.62560059045645	2.26806847256986	0.357532117886588	1.32810519436156	1.60882802736917	0.229415789995184	0.269204667976966	0.222231408083586	0.601810672970398	NA	NA	0.242854605960845	0.558449120110952	80.8315559830989
a7061	PIK3R1_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.71360997060723	3.41759338125766	0.296016589349568	0.988733164581765	1.13722340113691	0.26411764065274	0.299389764552687	0.260297659240597	0.601858636326007	NA	NA	0.773640436631753	0.67327757313823	80.8315559830989
a7062	loss_cnaOV34	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.3658620902115	2.53766342626697	-0.171801336055462	0.526017946574884	0.646004394744841	0.272128137937385	0.326607366106291	0.265944531419667	0.601959061317592	NA	NA	0.858325280106569	0.540695943820097	80.8315559830989
a7063	loss_cnaOV35	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	-0.0407822091847958	-0.384671017685621	0.343888808500825	1.0112461937956	1.46316054612604	0.243375968187539	0.340064378596151	0.235031493578287	0.601963290899626	NA	NA	0.889139681085334	0.536115255967777	80.8315559830989
a7064	PTEN_mut	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	2.88361912976678	3.33536729061239	-0.451748160845605	0.967378215622735	1.03651371932226	0.440340104823813	0.466981945168984	0.435834232026364	0.601966141955826	NA	NA	0.566467443833224	0.446699117764652	80.8315559830989
a7065	SMARCA4_mut	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.68661422480463	2.25688160976607	0.429732615038559	1.03202883158284	1.27580667173924	0.340919933454526	0.416395939616796	0.336832080093081	0.601986909116842	NA	NA	0.844766676789192	0.55639832090975	80.8315559830989
a7066	gain_cnaOV95_(MECOM)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	0.0345969642356958	-0.78508388959896	0.819680853834656	0.610911820856635	2.08890839668567	0.44293238760214	1.34173349712775	0.392396744220661	0.602206844837661	NA	NA	0.0431587745959648	0.204905944937559	80.8315559830989
a7067	loss_cnaOV36	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.39414922234329	2.94574598673615	0.448403235607143	1.20517377360457	0.990344524100151	0.445910417754037	0.372065212028309	0.45277499364635	0.602212608161343	NA	NA	0.0881729256684984	0.589542801710625	80.8315559830989
a7068	PTEN_mut	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	0.930770501643252	0.74041893678705	0.190351564856201	0.267434118799984	1.08971031343097	0.180424209064342	0.711769933134698	0.174680887672685	0.602348610209686	NA	NA	0.77227935516292	0.468725888180781	80.8315559830989
a7069	ARID1A_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	22	2.30258509299405	NA	2.12789950418157	2.18266678304873	-0.0547672788671596	0.946834310881506	1.42781547030805	0.0417162926159465	0.0578425160957371	0.0383573928186558	0.602444146958539	NA	NA	0.687014986945441	0.901717070171552	80.8315559830989
a7070	loss_cnaOV57_(ZNRF3)	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	2.90646984455991	3.44204838967415	-0.535578545114239	2.0929802142091	1.61916595552184	0.320207509380805	0.255892789371936	0.330774336804547	0.602499449826421	NA	NA	0.630305893260229	0.652208049427862	80.8315559830989
a7071	loss_cnaOV40	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	2.12419354029968	1.54472889584016	0.579464644459524	4.20362353730629	1.69135007408945	0.247667107039184	0.137848843816982	0.342604794440017	0.602595171037051	NA	NA	0.614340189025158	0.803394199133924	80.8315559830989
a7072	loss_cnaOV41	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.44209583657111	4.49860353930546	-0.0565077027343506	0.738101416209494	0.672499293361518	0.0828652035661101	0.0765581822407886	0.0840264120604414	0.602711848114022	NA	NA	0.0537848720120612	0.879513646897796	80.8315559830989
a7073	SMAD4_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	2.25240150491459	1.6668073445253	0.585594160389283	2.26642480584404	1.63156788334639	0.343783968164918	0.258377934656959	0.358914983781253	0.60275272093978	NA	NA	0.22996761477228	0.647812558017977	80.8315559830989
a7074	gain_cnaOV94	303	PIK-93	PI4K, PI3K	7	25	2.99573227355399	NA	3.01799181435742	2.8737756436812	0.144216170676224	0.729054464099797	1.35668893401533	0.1147762562734	0.197812615898726	0.106300100974064	0.602822362290923	NA	NA	0.232325241881928	0.713371111475907	80.8315559830989
a7075	loss_cnaOV70	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.84326468546809	3.36508814119176	0.478176544276338	1.3488146624704	1.21350342700128	0.390989734485098	0.354516122623209	0.394046307275764	0.602919323963059	NA	NA	0.327508642823515	0.607139761576099	80.8315559830989
a7076	PTEN_mut	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.12571511990271	0.894612295211593	0.231102824691114	0.387494490789543	1.34604377040723	0.180803267281968	0.596402865548431	0.171690423277392	0.602939714873659	NA	NA	0.957545892028912	0.48972185952368	80.8315559830989
a7077	gain_cnaOV26	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.79693889521438	-2.156239544996	0.359300649781628	1.57521793860104	1.27822363450428	0.276505377554802	0.228095834218803	0.281093730457403	0.60294754335253	NA	NA	0.608096530649179	0.734850386441644	80.8315559830989
a7078	loss_cnaOV16, loss_cnaOV17	301	PHA-793887	CDK-pan	6	26	2.32630161961136	NA	3.37230153315542	2.92619442129703	0.44610711185839	1.23849300315038	1.69310354155874	0.274327431351158	0.360201560060185	0.26348483770088	0.603081310848596	NA	NA	0.66395796058034	0.477978349654973	80.8315559830989
a7079	loss_cnaOV42	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.1153792451703	2.39142190391921	-0.276042658748909	1.27299642196043	0.812654165770718	0.317391465592787	0.216844803321441	0.339680358971779	0.603340827550531	NA	NA	0.651085078913761	0.698877265243889	80.8315559830989
a7080	gain_cnaOV96	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.51025508784881	4.23491898082797	0.275336107020845	1.01935562971641	0.877029281198993	0.306845654860162	0.270107996654167	0.313941749635122	0.603885591773955	NA	NA	0.52221831346483	0.594881964826795	80.8315559830989
a7081	gain_cnaOV50	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.43912691891553	3.71606967330358	-0.276942754388048	0.95217867165769	1.06849601036395	0.261899211609481	0.290851667477393	0.259189320036596	0.603969089807337	NA	NA	0.831253154776704	0.619630764283526	80.8315559830989
a7082	gain_cnaOV4_(KRAS)	345	KIN001-270	CDK9	8	24	2.99573227355399	NA	5.31515351235298	5.14934796586816	0.165805546484815	0.45026095142152	0.84854956753352	0.214173171657677	0.3682432286463	0.195398775544442	0.604056556155359	NA	NA	0.334382772210017	0.487890057679102	80.8315559830989
a7083	loss_cnaOV58	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	4.03349821548044	3.80361683081653	0.22988138466391	0.951388013022081	0.872391523867955	0.258881130773132	0.241627371290598	0.263507127676661	0.604108947676578	NA	NA	0.940003369534125	0.64386932162866	80.8315559830989
a7084	loss_cnaOV82	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	5.04085333490646	4.72579056396293	0.315062770943521	0.616113609996037	1.26856387450704	0.25517637044323	0.511371224124634	0.248361771350262	0.604200488512826	NA	NA	0.425642392938605	0.501860948305554	80.8315559830989
a7085	KRAS_mut	1031	Elesclomol	HSP70	7	24	-1.6094379124341	NA	-4.3102259347933	-3.98672413613609	-0.323501798657212	1.32643841400052	1.58015272831253	0.211285336962125	0.243887537666777	0.204728184093119	0.604232294129941	NA	NA	0.864312676678141	0.597740430218362	80.8315559830989
a7086	gain_cnaOV4_(KRAS)	1268	XAV 939	TNKS1 (tankyrase-1)	7	25	1.6094379124341	NA	2.66046133750131	2.91057503741707	-0.250113699915761	0.801013806031301	1.13435108225063	0.232452643156229	0.31224642825443	0.220490555198765	0.604298611235073	NA	NA	0.307587754081307	0.51961841436014	80.8315559830989
a7087	loss_cnaOV83	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.84580889975419	5.6908631415718	0.154945758182385	0.556689185127493	0.465184345578261	0.323885090993936	0.278334414107397	0.333084635489561	0.604396829800693	NA	NA	0.382490798362622	0.583117564270413	80.8315559830989
a7088	gain_cnaOV96	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	2.96010802696036	3.45195163534497	-0.491843608384603	2.05851845986653	1.60481198328767	0.294088698303326	0.238930870902412	0.306480518282893	0.604713800560107	NA	NA	0.630325597518556	0.634274795327077	80.8315559830989
a7089	loss_cnaOV40	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	0.454570461548601	0.0291462728704169	0.425424188678185	1.72723835496919	1.23612890279323	0.318436367211961	0.246303115869479	0.344158435027991	0.604735355762692	NA	NA	0.870257134117016	0.668874486152256	80.8315559830989
a7090	loss_cnaOV34	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.1063722895807	2.34457148440419	0.761800805176507	2.16748840916209	1.49759843972873	0.482934436323765	0.351467072191176	0.508681623168956	0.605153164178581	NA	NA	0.228599702598296	0.609468679518559	80.8315559830989
a7091	loss_cnaOV38	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	3.1063722895807	2.34457148440419	0.761800805176507	2.16748840916209	1.49759843972873	0.482934436323765	0.351467072191176	0.508681623168956	0.605153164178581	NA	NA	0.228599702598296	0.609468679518559	80.8315559830989
a7092	gain_cnaOV50	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.7067128107226	-4.11207813214551	0.405365321422913	1.43993588699721	1.5412204033126	0.26476235909805	0.281516229356744	0.263015802640327	0.605242958270901	NA	NA	0.864316336766956	0.629562799096584	80.8315559830989
a7093	gain_cnaOV95_(MECOM)	291	KIN001-266	MAP3K8 (COT)	9	23	2.99573227355399	NA	3.13617949343667	3.36750011787067	-0.231320624434005	0.784016244383567	1.20808430844012	0.208220317027945	0.295045703569422	0.191477219609522	0.605263200443898	NA	NA	0.95100715104207	0.530326146823443	80.8315559830989
a7094	loss_cnaOV16, loss_cnaOV17	1005	Cisplatin	DNA crosslinker	6	25	1.79175946922805	2.30258509299405	3.40038126681613	2.93313327051042	0.467247996305712	1.46753665484638	1.12024441191932	0.393507943720998	0.318389319110141	0.417094690528448	0.605270379381422	NA	NA	0.0890772008780977	0.490691594974174	80.8315559830989
a7095	gain_cnaOV95_(MECOM)	1248	FK866	NAMPT	8	24	0	NA	-1.20531762561048	-1.87603779044623	0.670720164835745	2.83741922253294	2.74162128413959	0.242639068204973	0.236383879938967	0.244643623361072	0.605339762126331	NA	NA	0.0449063823707705	0.570392299374667	80.8315559830989
a7096	loss_cnaOV87, loss_cnaOV88	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.29876708790557	0.883943662644279	0.414823425261292	1.16960692044536	1.28198881972289	0.325532914317871	0.354669092675456	0.323578036625122	0.605424593841914	NA	NA	0.957548846752411	0.610606290654143	80.8315559830989
a7097	loss_cnaOV81_(RB1)	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	1.03732698382461	0.718398312016277	0.318928671808337	0.396024594111783	1.09990170670989	0.303467983856468	0.80532541804289	0.289961066395961	0.605451895067928	NA	NA	0.772297261143178	0.288943865872013	80.8315559830989
a7098	TP53_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	22	10	0.246860077931526	2.32630161961136	1.10492137972379	0.782541759014483	0.322379620709308	1.51243198506178	1.64819473185125	0.207397261027675	0.213153136070539	0.195595589816751	0.605455387800619	NA	NA	0.791344831125841	0.606016970125812	80.8315559830989
a7099	loss_cnaOV34	1004	Vinblastine	Microtubules	5	26	-2.30258509299405	NA	-3.47698849883762	-3.28407257196162	-0.192915926876007	1.91246688953118	1.82440839567435	0.105027961510537	0.100872819253513	0.105741635114927	0.605474423323543	NA	NA	0.140113778169774	0.84265796808954	80.8315559830989
a7100	loss_cnaOV36	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.23692736654152	3.95325061252355	0.283676754017976	1.24898013501885	0.715828530414363	0.371766530984028	0.227126714079961	0.39629148876445	0.605486283706681	NA	NA	0.526261991031436	0.733987269456855	80.8315559830989
a7101	ARID1A_mut	164	JQ12	HDAC	5	14	1.63315443905142	NA	1.64059927861381	1.8486408356268	-0.208041557012991	1.92703350843219	2.33033565251982	0.0927937783124577	0.107959491157085	0.0892753611644028	0.605582216606172	NA	NA	0.661324184810383	0.849447072801543	80.8315559830989
a7102	gain_cnaOV26	290	KIN001-260	IKK	3	28	2.99573227355399	NA	5.13894402176488	4.81931453542116	0.319629486343726	0.783868781810222	0.912567079283413	0.353463128623906	0.407758918023999	0.350253141494774	0.605586580325259	NA	NA	0.665899778292183	0.56264336296702	80.8315559830989
a7103	loss_cnaOV44	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.989798714993058	0.520267665722282	0.469531049270776	1.98488001313182	1.13655188337536	0.38668823671165	0.236553870341982	0.413118887169805	0.605756968147249	NA	NA	0.431706248589828	0.723814691556037	80.8315559830989
a7104	loss_cnaOV54	1061	SB590885	BRAF	11	22	1.6094379124341	NA	3.71343057437807	4.03459444919529	-0.321163874817222	1.55017093314407	1.13634284148526	0.250032885751044	0.207179652224438	0.28262938181354	0.605761330888161	NA	NA	0.573756890499039	0.55063234116957	80.8315559830989
a7105	gain_cnaOV26	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	1.08308458173597	0.724662307811941	0.358422273924031	1.45161282742769	1.01641956235271	0.341012396695662	0.24691313492949	0.352632207406938	0.605853563525756	NA	NA	0.772299564456083	0.713634247896648	80.8315559830989
a7106	loss_cnaOV40	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.17661255633434	2.41337822178984	-0.236765665455493	1.00400596168395	0.835772010878307	0.271514281613339	0.235820975662718	0.283289775649077	0.605865705449621	NA	NA	0.608517763079945	0.582831570560163	80.8315559830989
a7107	loss_cnaOV56	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.64339600943467	3.050111291005	-0.406715281570329	2.11898799914436	0.968556061297752	0.375223273607899	0.191938454457769	0.419919194997735	0.606028869952888	NA	NA	0.435294552013829	0.772307808746374	80.8315559830989
a7108	loss_cnaOV39	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-3.08045095087062	-2.62827017945221	-0.452180771418409	1.45599135602624	1.14529650792914	0.368974084623585	0.310565560397639	0.394815463321386	0.606048908964018	NA	NA	0.380283357558766	0.553328426436441	80.8315559830989
a7109	gain_cnaOV50	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	1.79816553313739	1.91450727883733	-0.116341745699941	0.666180638045619	1.44659563204854	0.0836780185672274	0.174639938562691	0.080424510569819	0.606157185904441	NA	NA	0.0345370898512443	0.792755143671329	80.8315559830989
a7110	gain_cnaOV48_(SOX17)	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	3.77683073493565	4.11580062468684	-0.338969889751183	1.29905091454465	1.11142977431655	0.301330185674453	0.260936569888026	0.304985431904257	0.606319590604206	NA	NA	0.819931133858527	0.700359681455194	80.8315559830989
a7111	loss_cnaOV36	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.31925671676561	4.54917832240266	-0.229921605637059	2.3130186142251	0.828820794006965	0.231338287658983	0.0994032664601303	0.277408104742998	0.6063199421768	NA	NA	0.326283938730228	0.879553759717508	80.8315559830989
a7112	loss_cnaOV52, loss_cnaOV53	1007	Docetaxel	Microtubules	8	23	-4.38202663467388	NA	-4.69380176706701	-4.63284393101089	-0.0609578360561276	0.905282989815982	1.56377268147944	0.0425443133702011	0.0673356693342029	0.0389812642068008	0.606369868766182	NA	NA	0.136093370886187	0.89509805183842	80.8315559830989
a7113	RB1_mut	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-5.2221980786884	-4.58711536834719	-0.63508271034121	0.353449497664827	1.4683644090533	0.447284212338841	1.79681316436176	0.432510285883779	0.606574008942336	NA	NA	0.136095429577483	0.0882064433325538	80.8315559830989
a7114	loss_cnaOV20	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.22661459872741	-0.16137209940764	0.38798669813505	1.31925908546097	1.25661003175428	0.307137373304937	0.294094391625495	0.308756645523038	0.606584733164114	NA	NA	0.767530168585646	0.611245479507497	80.8315559830989
a7115	gain_cnaOV95_(MECOM)	196	Phenformin	AAPK1 (AMPK) agonist	8	23	8.29404964010203	NA	9.03385870645235	8.66138682812039	0.372471878331966	1.68328062134297	1.72526154264249	0.217156621250072	0.221277351862339	0.215892993106118	0.606692734677557	NA	NA	0.921930380684834	0.601610946007868	80.8315559830989
a7116	SMAD4_mut	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.82507573363703	4.55463168717131	0.27044404646572	1.34375598388049	0.892988617176596	0.285350008283116	0.201259789507864	0.302852736601274	0.6067719821319	NA	NA	0.943237442185671	0.719513306053941	80.8315559830989
a7117	loss_cnaOV33_(ZFHX3)	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	3.78681432611485	3.35607474451806	0.430739581596784	1.01243878753317	1.24377431474991	0.352310913095267	0.425447530162579	0.34631651135471	0.606790492193235	NA	NA	0.32755654032918	0.479539789192606	80.8315559830989
a7118	gain_cnaOV95_(MECOM)	1175	AG-014699	PARP1, PARP2	8	25	1.6094379124341	NA	4.08768755591715	3.84146845294297	0.246219102974183	0.994970352005628	1.10097287941953	0.228414562156046	0.24746375857116	0.223637754913634	0.606795766695585	NA	NA	0.317194730183588	0.563184941518493	80.8315559830989
a7119	loss_cnaOV36	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-3.04317687651503	-3.7605955162411	0.717418639726068	2.98671806731827	1.59776755597814	0.414754692634557	0.240202999933712	0.449013147777226	0.60684500605743	NA	NA	0.245992308446444	0.719602591314227	80.8315559830989
a7120	loss_cnaOV33_(ZFHX3)	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	4.67187034396457	4.34655803844114	0.325312305523425	0.845631381287355	1.00183893143515	0.329486594579191	0.384697532189714	0.324715176577745	0.606925937945517	NA	NA	0.51219256702091	0.518673052465537	80.8315559830989
a7121	loss_cnaOV55	228	KIN001-102	AKT1	7	25	2.32630161961136	NA	2.72310876829628	2.80727063532298	-0.0841618670266979	1.69989118402976	1.09295107595638	0.0679618237288402	0.0495101497186331	0.0770042400599245	0.606980921861683	NA	NA	0.0953183781126845	0.904589082202952	80.8315559830989
a7122	gain_cnaOV94	1239	YK 4-279	RNA helicase A	5	19	2.30258509299405	NA	1.47831584808981	1.59350738899756	-0.115191540907747	1.46326627748406	0.955838289806605	0.108037906562614	0.0787222002449254	0.120513628859808	0.60700524778501	NA	NA	0.288094470517231	0.874066666431228	80.8315559830989
a7123	loss_cnaOV38	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	3.54385671766559	4.06252246672595	-0.518665749060356	3.1580492670752	0.898342119665089	0.333095007041188	0.164236117044721	0.577358823221737	0.607028336664068	NA	NA	0.743825486938171	0.765707609779075	80.8315559830989
a7124	PIK3CA_mut	304	SB52334	ALK5	6	26	2.99573227355399	NA	4.39750528619891	4.35951782794568	0.0379874582532294	0.879271624131887	1.10546619116669	0.0354661854529595	0.0432033255829616	0.0343632926603917	0.607031315811397	NA	NA	0.352626117570503	0.929789964938397	80.8315559830989
a7125	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	224	AS605240	PI3Kgamma	7	25	2.99573227355399	2.32630161961136	3.67750910515203	3.29042682212207	0.387082283029963	1.79342881993374	1.64334251968111	0.231171691075507	0.215833647105249	0.235545711496029	0.607104104513885	NA	NA	0.630346695336398	0.619711272827826	80.8315559830989
a7126	loss_cnaOV54	1161	ZG-10	IRAK1	6	17	2.30258509299405	NA	1.50117835339918	1.60459853358202	-0.103420180182835	0.68356531002942	1.40525118444085	0.0813598606270918	0.151295243724969	0.0735955118401029	0.607160813450258	NA	NA	0.164883865129364	0.81698449934178	80.8315559830989
a7127	loss_cnaOV38	1243	piperlongumine	Increases ROS levels	8	24	2.30258509299405	NA	1.78539928684692	1.55749921153527	0.227900075311647	0.653101552112568	0.690247727446697	0.334281312146605	0.348950442047589	0.330171424330037	0.607198406678852	NA	NA	0.209816406516298	0.415144249953637	80.8315559830989
a7128	gain_cnaOV72_(ASXL1)	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	2.11120202892714	1.86276296693559	0.248439061991555	0.982253024740143	1.43825671175363	0.179008447686175	0.252927764775558	0.172736243788246	0.607383872546062	NA	NA	0.0345422233894302	0.644296811439642	80.8315559830989
a7129	loss_cnaOV83	152	CP466722	ATM	5	27	2.77258872223978	NA	2.85354246104831	2.60865265241414	0.244889808634172	0.586452870785728	0.845191813303881	0.300312280116886	0.417577985944666	0.289744652964503	0.607515854967431	NA	NA	0.556591528182826	0.451854967112747	80.8315559830989
a7130	loss_cnaOV56	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	2.06471085499009	1.70509621486406	0.359614640126031	2.15818175129061	1.67624016699082	0.210124804405252	0.166628524178272	0.214536465124571	0.60756980773742	NA	NA	0.230022608834499	0.802985467444624	80.8315559830989
a7131	loss_cnaOV82	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.14131732594489	3.90549755160377	0.23581977434112	0.843171601737464	0.723624303611426	0.322069451295042	0.279681827347106	0.325887028896353	0.607570025286663	NA	NA	0.955864424150024	0.680843602629896	80.8315559830989
a7132	loss_cnaOV85	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.74592836081215	4.54433966598639	0.201588694825761	0.867665077604447	0.967477589693446	0.212566508281983	0.232334687691166	0.208365234474977	0.607680704727458	NA	NA	0.943238770265221	0.607441479485673	80.8315559830989
a7133	loss_cnaOV55	253	XMD14-99	EPHB3, CAMK1	7	25	2.32630161961136	NA	5.04162896095702	4.80922566229734	0.232403298659682	0.548909856840463	0.633596550140608	0.376307427631044	0.423390645592338	0.366800132683971	0.607720532339127	NA	NA	0.0500233500958804	0.359750188677685	80.8315559830989
a7134	gain_cnaOV48_(SOX17)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.762944950769484	1.26137081467402	-0.498425863904538	0.628085375860136	1.27138827155519	0.401957191667355	0.793563873736059	0.392032768475088	0.607810571387026	NA	NA	0.267728899097716	0.312502317667237	80.8315559830989
a7135	gain_cnaOV49	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.91699649394819	2.33934065235783	-0.422344158409636	1.18644621232169	1.26607220801207	0.334996440941133	0.355974130157301	0.333586153883579	0.60783658994206	NA	NA	0.844790819070758	0.608513530460848	80.8315559830989
a7136	loss_cnaOV81_(RB1)	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	4.20224305209127	3.94807420194437	0.254168850146902	0.683426856266249	0.771214958423879	0.333165408531541	0.371903515082063	0.329569398739805	0.607996102306787	NA	NA	0.526288627065373	0.529955747345189	80.8328114730793
a7137	SMAD4_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.55130392859493	-4.06330121794975	0.511997289354813	2.47405739184332	1.72858493205116	0.27945931962022	0.206946407566295	0.296194465115042	0.608016415278567	NA	NA	0.591538948963215	0.759523177139945	80.8328114730793
a7138	loss_cnaOV34	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-1.89794100781816	-2.16386778558687	0.26592677776871	1.04945120453142	1.33320994981201	0.204546355384771	0.253396038444155	0.1994635412121	0.608391152707837	NA	NA	0.608145242752018	0.633930927540583	80.8486837464736
a7139	gain_cnaOV96	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	2.47560443699783	2.04377038714444	0.431834049853392	0.645490397403904	1.48359213028125	0.316086566041516	0.669001508915059	0.291073295037989	0.608395338655839	NA	NA	0.89259987011695	0.414327650412789	80.8486837464736
a7140	loss_cnaOV1	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	1.32103534280453	0.802953594528447	0.518081748276085	1.55009204324739	2.12398416784331	0.248096244981968	0.334226441928392	0.243919778743993	0.608437930935457	NA	NA	0.416823595390494	0.635960121822207	80.8486837464736
a7141	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1026	17-AAG	HSP90	3	30	0	NA	-0.839403303822176	-0.499975043736836	-0.33942826008534	2.39693734773513	2.30752273167858	0.146722957429064	0.141609149862038	0.147096388445295	0.608476640485524	NA	NA	0.0616952089931913	0.833122582863061	80.8486837464736
a7142	loss_cnaOV35	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	5.10870435980137	4.90711995782085	0.201584401980518	1.17218447048588	0.756649091556127	0.245190595405949	0.17197327473291	0.266417292018337	0.608588385566832	NA	NA	0.946068144210232	0.727064386968897	80.8522091344485
a7143	loss_cnaOV83	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	5.29808986029951	4.61736845757481	0.680721402724698	2.25753231407661	1.37046092872411	0.435243818379119	0.301533403743605	0.496709821095333	0.609001062080901	NA	NA	0.122697678548778	0.598922120755509	80.8858176110013
a7144	loss_cnaOV58	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.69905475019296	3.4493331928252	0.249721557367758	0.586772562212759	1.18253851074174	0.223089769236511	0.425584925828913	0.211174143674292	0.609013847336249	NA	NA	0.72727312566978	0.489947615431643	80.8858176110013
a7145	gain_cnaOV72_(ASXL1)	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	3.6509060687277	4.03397597310939	-0.383069904381689	1.15735196208502	1.63850575632233	0.244869037100003	0.330988253298135	0.233792223740184	0.60917505538615	NA	NA	0.743850478219226	0.610442864898532	80.8858176110013
a7146	loss_cnaOV102	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	0.530620955428692	1.05316638199249	-0.522545426563795	0.638003506876584	1.59959170089564	0.33623502540455	0.819032216800772	0.326674254605855	0.609182354391224	NA	NA	0.791364394631157	0.317171309861038	80.8858176110013
a7147	KRAS_mut	256	JW-7-24-1	LCK	7	25	2.32630161961136	NA	1.68707335255264	2.00998004526253	-0.322906692709894	0.829082608107766	1.44659924202227	0.239908966188137	0.389474691125014	0.2232177947629	0.609487545974624	NA	NA	0.839329318459195	0.459102420314113	80.9094979492231
a7148	loss_cnaOV84	1248	FK866	NAMPT	6	26	0	NA	-1.7777154401238	-1.69235212826348	-0.0853633118603161	3.68908654928151	2.56009932466812	0.0307030815760179	0.0231394169586348	0.0333437500013333	0.609606254307483	NA	NA	0.0449283539260415	0.958820128814945	80.9094979492231
a7149	KRAS_mut	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.39355878662832	4.55049770671564	-0.156938920087325	0.492864410909546	0.624362435402619	0.261403055358829	0.318422098681674	0.251358683976756	0.609616519104445	NA	NA	0.615675108443078	0.497403810866388	80.9094979492231
a7150	loss_cnaOV85	290	KIN001-260	IKK	7	24	2.99573227355399	NA	4.72374952854996	4.88714134821822	-0.163391819668257	1.26992476641063	0.784907088335578	0.180185926867777	0.128662597966394	0.208167083845216	0.609738768425487	NA	NA	0.665934441006222	0.755722378949572	80.9144048355032
a7151	loss_cnaOV83	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.22947336333308	3.52696203724079	-0.297488673907711	1.28870999244052	1.07948137429515	0.265792928035328	0.2308422186937	0.275584814144624	0.609974405839615	NA	NA	0.773725303454216	0.692578957393331	80.9217949132361
a7152	loss_cnaOV56	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.61842439478206	4.81334445405482	-0.194920059272768	0.881336659376977	0.649135754097686	0.292174860917625	0.221164134271412	0.300276264313481	0.610002920434945	NA	NA	0.762503880489985	0.741818808283447	80.9217949132361
a7153	gain_cnaOV18_(CCNE1)	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	6.92600847264341	6.6367439776996	0.289264494943811	2.4625713702279	1.24255669393949	0.189031521884029	0.11746441075413	0.232797824320359	0.610050314925804	NA	NA	0.338479291855069	0.833095403920168	80.9217949132361
a7154	ARID1A_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	-0.0260726535460157	-0.763416168962635	0.737343515416619	2.56449800567908	1.57832849901378	0.396833144209528	0.287519629098471	0.467167332958473	0.610228215131528	NA	NA	0.0432289245269386	0.571948347889441	80.9330876032681
a7155	loss_cnaOV40	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	3.12677145087081	2.9354709402031	0.191300510667709	0.756097492783331	0.56689587412018	0.316407277208518	0.253010375637535	0.337452642365067	0.6103060435305	NA	NA	0.85000873730568	0.661905799779726	80.9330876032681
a7156	loss_cnaOV82	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.24448567179579	0.830435441447221	0.41405023034857	3.14823536112643	0.983493764078922	0.331130527308975	0.131518194433984	0.420999344857405	0.610708490769345	NA	NA	0.845167932829762	0.84137860323012	80.9427456783075
a7157	gain_cnaOV94	155	AP-24534	ABL	3	16	-0.669430653942629	NA	0.380655192235536	0.865031274821113	-0.484376082585577	2.17273857233691	1.08373796778427	0.383929990225627	0.222933439279168	0.4469494444085	0.610720856800976	NA	NA	0.585385791860676	0.739324396464433	80.9427456783075
a7158	loss_cnaOV57_(ZNRF3)	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	-0.319391678252122	-0.13383453348993	-0.185557144762192	2.51985032012517	1.48244326587253	0.114481350763636	0.0736381614734063	0.125169811913832	0.610787312577714	NA	NA	0.101177051508707	0.894080917496745	80.9427456783075
a7159	loss_cnaOV52, loss_cnaOV53	281	CH5424802	ALK	8	24	1.63315443905142	NA	3.81590516137329	3.96483915347324	-0.148933992099944	0.883500441387571	0.680078944199574	0.203291327848243	0.168572628968966	0.218995152504293	0.610868539900464	NA	NA	0.955868148795815	0.672378291358102	80.9427456783075
a7160	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	262	VX-11e	ERK	7	25	1.63315443905142	NA	2.67468491678926	2.91096353503998	-0.236278618250719	1.05837289095589	1.14113325795647	0.210012684564465	0.223247042956022	0.207056114264731	0.610878587229348	NA	NA	0.391617302688918	0.618783416834825	80.9427456783075
a7161	loss_cnaOV70	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.44509355798263	3.91869477654275	0.526398781439885	0.48382845942776	1.2014612472875	0.451366485893308	1.08798639514194	0.438132135038329	0.6108907219491	NA	NA	0.0834007595472635	0.199859822349032	80.9427456783075
a7162	loss_cnaOV40	304	SB52334	ALK5	7	25	2.99573227355399	NA	4.11947296902187	4.43584737842513	-0.316374409403258	0.627351307589608	1.14592057237207	0.297722635865664	0.504301825111074	0.27608755530792	0.61118632524285	NA	NA	0.352676611357959	0.349791031911399	80.9430987254922
a7163	loss_cnaOV58	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.25482096658812	4.34368813580158	-0.0888671692134615	0.450317780206998	0.610968364185756	0.150263253310758	0.197343238751559	0.145452979929486	0.611268315873067	NA	NA	0.254896707560107	0.715472915104815	80.9430987254922
a7164	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.6041216392621	2.36054353945366	0.243578099808443	1.32240311738468	0.941866502922089	0.244993147668739	0.184193531160277	0.25861212714621	0.611269937368425	NA	NA	0.411619051956873	0.784968968831757	80.9430987254922
a7165	gain_cnaOV95_(MECOM)	219	AT-7519	CDK9	9	23	2.32630161961136	NA	1.26242747176296	1.58977388469936	-0.327346412936404	1.36805982961296	1.82106249100406	0.191204526303677	0.239277848710034	0.179755727523616	0.611320465131953	NA	NA	0.316979102541557	0.587458203843798	80.9430987254922
a7166	loss_cnaOV16, loss_cnaOV17	1054	PD-0332991	CDK4, CDK6	6	27	1.38629436111989	0.693147180559945	2.82088192479537	2.16488454197304	0.655997382822327	2.07957270020265	1.72409763535678	0.367253778600527	0.315448160460273	0.380487374594987	0.611366558941463	NA	NA	0.111145170840839	0.496357998115936	80.9430987254922
a7167	BRCA1_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	1.54943540291549	1.1152447069991	0.434190695916392	1.27732493327422	1.51950887715114	0.289888694746943	0.339921882526331	0.285744099587255	0.611462575936263	NA	NA	0.813398417610125	0.565722253609684	80.9430987254922
a7168	loss_cnaOV52, loss_cnaOV53	228	KIN001-102	AKT1	8	24	2.32630161961136	NA	2.74319596821474	2.80408164647627	-0.0608856782615264	1.57481862805504	1.1163392720328	0.0491571817077932	0.038662025694173	0.0545404786760361	0.611585754706972	NA	NA	0.0953555880278307	0.921500411915201	80.9430987254922
a7169	gain_cnaOV51_(MYC)	1199	Tamoxifen	ER	8	24	1.6094379124341	NA	4.13504668866536	3.92811151472852	0.206935173936842	0.756612620702839	0.763914670389537	0.271491114078767	0.273502143996243	0.270887812419313	0.611610582176424	NA	NA	0.526326573583705	0.516435042029118	80.9430987254922
a7170	SMARCA4_mut	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.64756142308672	2.33200204033883	0.315559382747887	0.864739213750798	0.873270058330605	0.361588130860178	0.364918553166048	0.361353718403136	0.611698552762881	NA	NA	0.60857114654744	0.598871208462944	80.9430987254922
a7171	loss_cnaOV81_(RB1)	308	XL-880	MET	4	28	1.63315443905142	NA	-0.0386716131435696	0.294779831258714	-0.333451444402284	0.598862489296953	1.0054934772335	0.342876530105058	0.556808032497987	0.331629644500269	0.611795298834477	NA	NA	0.369152491315116	0.3845819349572	80.9430987254922
a7172	loss_cnaOV82	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.68280779947648	2.4930275710978	0.189780228378686	0.343406219109812	0.647740217087037	0.300272359830903	0.552640627390616	0.292988181638851	0.611860051000141	NA	NA	0.858361095204031	0.462471311917949	80.9430987254922
a7173	gain_cnaOV51_(MYC)	1025	SB 216763	GSK3A, GSK3B	5	18	2.30258509299405	NA	4.84422605543114	4.99210330506277	-0.147877249631625	0.618388901475808	0.875326703642394	0.177625543789892	0.2391330912937	0.168939493124431	0.611968752198248	NA	NA	0.455258311273226	0.678260945800208	80.9430987254922
a7174	gain_cnaOV95_(MECOM)	230	GSK429286A	ROCK2	9	23	2.99573227355399	2.32630161961136	5.68869585606524	5.48006968939579	0.208626166669446	0.793121627257776	1.0445281935038	0.212064034948826	0.263044354736325	0.199732441849773	0.612073413249392	NA	NA	0.305056354009639	0.549580233389027	80.9430987254922
a7175	PIK3R1_mut	134	Etoposide	TOP2	3	16	2.77258872223978	NA	3.0316102678178	2.14300464195192	0.888605625865887	1.16926905943164	1.89157266188416	0.487836601269595	0.759966766158872	0.469770812283132	0.612087703936301	NA	NA	0.410570578717135	0.337640089448338	80.9430987254922
a7176	MLL2_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	3.43940928666089	4.27540572365884	-0.83599643699795	0.617878928836637	0.968371364125813	0.880885628206222	1.35301010923287	0.863301485327002	0.612538976362332	NA	NA	0.0485233602196406	0.12364757763393	80.9816648605439
a7177	loss_cnaOV102	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.62300730328692	3.18901241071156	0.433994892575361	0.593923742917674	1.26767312047751	0.351625780183714	0.730724941965349	0.342355521754601	0.61269963797782	NA	NA	0.601594666463109	0.352278587743024	80.9816648605439
a7178	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	4	19	2.30258509299405	NA	4.05714934689455	3.81073666550113	0.246412681393418	1.09686964964622	0.848379998234977	0.27744635483905	0.224650833827789	0.29045083795713	0.612713745012049	NA	NA	0.940022704588293	0.694880546253132	80.9816648605439
a7179	loss_cnaOV34	179	5-Fluorouracil	DNA antimetabolite	5	26	3.46573590279973	NA	4.42447630490404	3.80222102153576	0.622255283368278	2.41768324763591	1.5715197855632	0.363199360250214	0.257376678262853	0.395957651366937	0.612999108725261	NA	NA	0.14803140932964	0.605381756096027	80.9816648605439
a7180	loss_cnaOV58	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-3.67360456403045	-4.24666824800453	0.573063683974079	1.98408811684589	2.41312628283241	0.243171642461211	0.288829754640676	0.237477701872048	0.613084630189019	NA	NA	0.928186492678058	0.58918758686134	80.9816648605439
a7181	loss_cnaOV70	1030	KU-55933	ATM	3	30	2.30258509299405	NA	3.90879747941047	4.17521447130272	-0.266416991892251	1.30509511403664	1.01395769663705	0.257354379175786	0.204136073322831	0.262749612509345	0.613180908492942	NA	NA	0.53041995577145	0.760818347547954	80.9816648605439
a7182	SMARCA4_mut	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	9.02998583002984	8.71953856868722	0.31044726134262	1.17617804010417	1.24673999172912	0.249957062501471	0.263945806465766	0.24900722155552	0.613287371052368	NA	NA	0.53071200771776	0.700184075042404	80.9816648605439
a7183	gain_cnaOV94	262	VX-11e	ERK	7	25	1.63315443905142	NA	2.98241051937896	2.82480036631486	0.1576101530641	1.26917902491442	1.0893026721656	0.139777870489909	0.124182759067207	0.144689035555896	0.613476484788588	NA	NA	0.391648090585133	0.771896548338927	80.9816648605439
a7184	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.56485607454625	1.12817566303324	0.436680411513007	1.93171321281858	1.464801578496	0.291252467947967	0.226058613988483	0.298115743404218	0.613581317327064	NA	NA	0.813407900062009	0.736559599137002	80.9816648605439
a7185	loss_cnaOV70	1061	SB590885	BRAF	3	30	1.6094379124341	NA	4.23570191708081	3.89672361497376	0.338978302107054	0.829577687712745	1.31586738132233	0.262766236558458	0.408615500546624	0.257608256666725	0.61358779158541	NA	NA	0.573830577278386	0.570321530544836	80.9816648605439
a7186	SMARCA4_mut	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.15684689699366	4.43525045057617	-0.27840355358251	0.438844673027018	0.643246254168486	0.44073471419547	0.634401123436605	0.43281022124629	0.613731104700121	NA	NA	0.272019443891429	0.394036269747762	80.9816648605439
a7187	gain_cnaOV19	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.47934516582648	2.89858094124292	-0.419235775416442	0.436466874009398	1.15603723385285	0.373480837280642	0.960521405817877	0.362649024737041	0.613773036200937	NA	NA	0.391651587062027	0.254318010115778	80.9816648605439
a7188	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	3.21177848051248	2.47157893086651	0.740199549645973	2.40516924737142	2.32658092584092	0.316701922212808	0.307753622933158	0.318149066479789	0.613777874313792	NA	NA	0.386851177269079	0.550805008404214	80.9816648605439
a7189	loss_cnaOV81_(RB1)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.303241057425393	0.593827414747389	-0.290586357321996	1.39563851729804	1.20538461810228	0.23829122796456	0.208210330770014	0.24107355690293	0.613843839736155	NA	NA	0.431803806800957	0.757442960020432	80.9816648605439
a7190	gain_cnaOV94	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	6	25	3.68887945411394	NA	3.25333907127904	3.54631609346984	-0.292977022190799	0.792898762944333	1.17331224857776	0.262287953422204	0.369501172006959	0.249700812844946	0.613847662463981	NA	NA	0.727306387128171	0.479006280120129	80.9816648605439
a7191	loss_cnaOV81_(RB1)	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.50431630390274	2.97205965899818	0.53225664490456	1.1777985780244	1.19259113771615	0.446682596964319	0.451908038297471	0.44630270012223	0.613974068928166	NA	NA	0.0891472342885921	0.521960889363641	80.9816648605439
a7192	gain_cnaOV26	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.41273456543818	3.97222240537263	0.440512160065546	1.39547045349459	1.02137356260073	0.419349141378725	0.315672867857859	0.431293873461799	0.614153055255887	NA	NA	0.105315678975975	0.642944938976351	80.9816648605439
a7193	loss_cnaOV56	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.54096033508175	3.96045365877125	-0.419493323689499	0.910843366843099	1.24514184635072	0.342438186030716	0.460554842863296	0.336904044241189	0.614177086009791	NA	NA	0.69931237214538	0.521351377511504	80.9816648605439
a7194	gain_cnaOV4_(KRAS)	1373	Dabrafenib	BRAF	7	25	2.30258509299405	NA	3.99147177010258	3.54964577283051	0.441825997272068	1.98286215309897	2.04810910979122	0.217089289434044	0.222822346264236	0.215723857269062	0.614183691807443	NA	NA	0.747865246363679	0.616302724693468	80.9816648605439
a7195	loss_cnaOV81_(RB1)	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	3.7343616626555	3.51723138842074	0.217130274234759	0.961138442690232	0.90254924765431	0.238978081227696	0.225909467971139	0.240574433804108	0.614279373106464	NA	NA	0.663867876362383	0.693277248857959	80.9816648605439
a7196	PIK3CA_mut	298	OSI-930	KIT, VEGFR, PDGFR	6	26	2.32630161961136	NA	3.8860190919099	4.58207697617883	-0.696057884268928	0.797750733639018	0.979755134552682	0.731275434533026	0.872525533249956	0.710440659835603	0.614371628951222	NA	NA	0.0315946900896983	0.0992719114883988	80.9816648605439
a7197	gain_cnaOV49	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	2.45880660146908	2.95151427545258	-0.492707673983497	0.380877820819012	1.28906441747575	0.394408648404244	1.29361083017125	0.382221142174043	0.614396947843035	NA	NA	0.23246059635992	0.165113869696237	80.9816648605439
a7198	loss_cnaOV1	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.33840344702042	1.89806221580588	0.440341231214543	0.713185131388275	1.38065253061929	0.327029428219001	0.617429068322529	0.318937039877099	0.61442640162565	NA	NA	0.839349158177104	0.417692777695311	80.9816648605439
a7199	loss_cnaOV20	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-0.195192389640752	-0.651422408173761	0.456230018533008	1.21787940506064	1.54812077568669	0.305139435137556	0.374610176210586	0.294699241621276	0.614459228029837	NA	NA	0.909503130267699	0.554510130573829	80.9816648605439
a7200	loss_cnaOV1	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.70845719623177	4.4962752615722	0.212181934659567	0.366648837142927	0.614026671181312	0.353217070164495	0.578706143766806	0.345558172988406	0.61451306505996	NA	NA	0.615718757673403	0.436936407034824	80.9816648605439
a7201	loss_cnaOV16, loss_cnaOV17	283	GSK2126458	PI3K, MTOR	6	26	-2.05572501506252	0.0237165266173161	-2.35323157048824	-2.81963328806337	0.466401717575125	1.66009685254971	1.79514829925657	0.263005407021609	0.280948498190806	0.259812360777256	0.614741647847314	NA	NA	0.696815273798474	0.558456431853471	80.9825550557593
a7202	gain_cnaOV26	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.15432114110874	4.41131527685807	-0.256994135749328	1.11174107908242	0.98131781404048	0.259446659096783	0.231163659043201	0.261886752764815	0.614758329234276	NA	NA	0.512276084771477	0.732434048429444	80.9825550557593
a7203	gain_cnaOV26	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.23129479184982	3.95383329266407	0.277461499185752	0.431407044132549	0.781588451671267	0.363522607593684	0.643154772179617	0.35499692784925	0.614818417707785	NA	NA	0.526359846000403	0.39653038599123	80.9825550557593
a7204	loss_cnaOV56	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.88002825306275	5.50344071729318	0.376587535769568	1.21284523449562	0.96342382064597	0.383480686126287	0.310499250076352	0.390884601044085	0.614861220027258	NA	NA	0.305089754766238	0.648770730248102	80.9825550557593
a7205	loss_cnaOV55	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	3.12487992501425	2.93597534709818	0.188904577916069	0.148424170894556	0.662841867190524	0.312372158993533	1.27273460095843	0.28499192230682	0.615124198940207	NA	NA	0.850041900202716	0.32544999532973	81.0059470802818
a7206	gain_cnaOV50	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.337574912233302	-0.0241951964630943	-0.313379715770208	1.09696067496875	0.950851596950901	0.324256238956035	0.285679991016211	0.329577945470275	0.615670502175801	NA	NA	0.549704492205557	0.618402741271138	81.0344457527067
a7207	loss_cnaOV82	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	1.35983618592821	0.627491779369059	0.73234440655915	2.14249310885194	2.33139053826101	0.315764222827337	0.34181879210411	0.314123436009742	0.615746060979609	NA	NA	0.945942955149733	0.622079089815046	81.0344457527067
a7208	gain_cnaOV18_(CCNE1)	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.80888352881017	4.55694485928944	0.251938669520735	0.667970448986455	0.974544434561047	0.265657956226579	0.377170382167376	0.258519427730571	0.615795166478593	NA	NA	0.943250441246068	0.537829289317227	81.0344457527067
a7209	loss_cnaOV102	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.65178705463726	3.04924325184611	-0.397456197208852	1.65639946532204	1.03129545873537	0.36657586806347	0.239951899001354	0.385395081343839	0.615833261178792	NA	NA	0.435407948359584	0.720449027682654	81.0344457527067
a7210	loss_cnaOV34	1378	Bleomycin (50 uM)	DNA damage	5	27	3.91202300542815	NA	1.84218751442958	2.0788872868781	-0.236699772448517	3.47811348285128	1.66262041927087	0.118221357499154	0.068054068280278	0.142365491067601	0.615841163462533	NA	NA	0.133160604733797	0.888178539522984	81.0344457527067
a7211	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.39602982674342	1.65143826154378	0.744591565199641	2.19288087110676	1.54305746537179	0.466422742136555	0.339549482605428	0.482542991372158	0.615920168231832	NA	NA	0.0416014167567028	0.619376227315094	81.0344457527067
a7212	loss_cnaOV39	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	-0.837621064748659	-0.454571454101866	-0.383049610646793	1.58609331506603	1.46909556876193	0.255801770035182	0.24150509116221	0.260738388156466	0.615938438207613	NA	NA	0.909509270860265	0.65173552411894	81.0344457527067
a7213	loss_cnaOV81_(RB1)	281	CH5424802	ALK	4	28	1.63315443905142	NA	3.75574594266831	3.95215704298824	-0.196411100319931	0.195591104763535	0.769438960337581	0.268112532783102	1.00419239697729	0.255265343249266	0.616357170015451	NA	NA	0.955874250452647	0.275611053326108	81.0639138210772
a7214	loss_cnaOV55	221	TAK-715	p38a	7	25	2.99573227355399	2.32630161961136	4.4677642542908	4.22478952566254	0.242974728628263	0.653637513724385	0.948431758841991	0.270797836361331	0.371727025341322	0.256185778642554	0.616413925104924	NA	NA	0.522350430143487	0.448378751088939	81.0639138210772
a7215	loss_cnaOV34	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	1.47813126367765	1.6052549373834	-0.127123673705745	1.26002636683757	1.27338208630946	0.100030513140566	0.100889693304435	0.0998315235250224	0.616486255859764	NA	NA	0.165023018706998	0.848286325516984	81.0639138210772
a7216	TP53_mut	1218	JQ1	BRD2, BRD3, BRD4	22	9	0	NA	2.3519613465231	2.15226675502383	0.199694591499272	0.987001222475438	0.633597172071652	0.221041517897881	0.202324563487804	0.31517595137986	0.616608968949412	NA	NA	0.595138201394017	0.509621491659352	81.0639138210772
a7217	gain_cnaOV4_(KRAS)	1059	AZD8055	MTORC1/2	7	26	0.693147180559945	NA	0.478468841509549	0.227992790852812	0.250476050656737	1.39764834306482	1.07318421852951	0.219102055020105	0.179212497835817	0.233395204972304	0.616727676294897	NA	NA	0.147544283830543	0.671238929393359	81.0639138210772
a7218	gain_cnaOV95_(MECOM)	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	3.08724510225979	2.93592317108791	0.151321931171881	0.587464901760538	0.61174321906326	0.249657474040982	0.257584633087684	0.247361844735434	0.616837803678864	NA	NA	0.850053557397108	0.639068851810591	81.0639138210772
a7219	loss_cnaOV1	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.06683415426561	2.8340380287979	0.232796125467709	0.404792243826755	1.11160839165452	0.215753796479377	0.575100261968808	0.209422785232139	0.617004316998589	NA	NA	0.307741580549686	0.483201633110483	81.0639138210772
a7220	loss_cnaOV83	308	XL-880	MET	5	27	1.63315443905142	NA	0.393825398114067	0.22703784563331	0.166787552480756	0.328520945567343	1.04169747479652	0.17068623442666	0.507692293995808	0.160111314960551	0.617051115122311	NA	NA	0.369214882038651	0.509377500801399	81.0639138210772
a7221	gain_cnaOV50	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	2.93448025377423	3.0862532977966	-0.151773044022376	0.918482924818068	0.925428407919287	0.164121807762668	0.165243185171286	0.164003009550592	0.617137276740793	NA	NA	0.239742623613431	0.772787259498303	81.0639138210772
a7222	gain_cnaOV26	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	3.90978847156444	3.5263811387219	0.383407332842545	0.471836159853461	0.940568472808309	0.417845285740712	0.812585735187445	0.407633621503158	0.617142430579924	NA	NA	0.143635709218381	0.30178205159424	81.0639138210772
a7223	PTEN_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	3.7113750030574	4.26641049406641	-0.555035491009001	0.728618497016204	0.986005459443348	0.576141707568451	0.761764206209354	0.562913202653409	0.617401041773951	NA	NA	0.0485490195345698	0.236008821711823	81.0639138210772
a7224	loss_cnaOV58	305	TPCA-1	IKK	5	27	2.99573227355399	NA	3.58165716429486	3.27770202016324	0.30395514413162	1.45551880833088	1.19799834613481	0.246029921837139	0.208829416969322	0.253719168404775	0.617412422414299	NA	NA	0.993624109483074	0.67800635692536	81.0639138210772
a7225	loss_cnaOV20	134	Etoposide	TOP2	4	15	2.77258872223978	NA	2.57316088893296	2.20601743459682	0.367143454336146	3.06089965647362	1.46059993252872	0.19881203900609	0.119946256179832	0.251364830409458	0.617413912136908	NA	NA	0.410683183157086	0.829253299568662	81.0639138210772
a7226	PTEN_mut	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.28830641718662	8.81791895350315	-0.529612536316533	1.18393189132452	1.23745092694713	0.429872527417799	0.447333617919548	0.427986698125574	0.617438115405223	NA	NA	0.530755999394243	0.452788442863122	81.0639138210772
a7227	loss_cnaOV58	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-1.21209902428229	-1.16776333961109	-0.0443356846711933	1.28455945872022	1.35805149273742	0.0329789584881512	0.0345143110116242	0.0326465416873303	0.617443959223458	NA	NA	0.0498675104652645	0.948212260725857	81.0639138210772
a7228	loss_cnaOV41	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.23807648288953	1.88402341425867	0.354053068630861	0.758118564929184	1.41544042933448	0.262949595789477	0.467015431371125	0.250136325975465	0.617657906096744	NA	NA	0.839361951657966	0.434234774533892	81.064065856622
a7229	gain_cnaOV48_(SOX17)	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.2824828282216	4.42225363010432	-0.13977080188272	0.66167563268111	0.633938764507383	0.219825713872864	0.211237644216046	0.220479973316243	0.617672842663601	NA	NA	0.272065765958029	0.75499758818688	81.064065856622
a7230	loss_cnaOV42	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	4.96701035895663	4.77050788986106	0.196502469095571	0.920890005890864	0.631755497158434	0.294898751020317	0.213383213889346	0.311041961612391	0.617701424886113	NA	NA	0.762548490914724	0.704121047008415	81.064065856622
a7231	gain_cnaOV51_(MYC)	1007	Docetaxel	Microtubules	8	23	-4.38202663467388	NA	-4.27299532615336	-4.77921138871998	0.506216062566618	1.44322459532373	1.40544412525248	0.357836878238142	0.350753489239883	0.360182275105159	0.617852283841554	NA	NA	0.136206915698933	0.406536819455909	81.0726504683917
a7232	loss_cnaOV41	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.73113114769672	3.0639911010728	-0.332859953376078	1.42694717323529	1.02064534155121	0.307163667006338	0.233267187194737	0.326126951081937	0.618372783890939	NA	NA	0.435436682779605	0.64016976933428	81.1189965339742
a7233	NF1_mut	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.18341140566202	2.42355079063572	-0.240139384973694	1.39257819065834	0.883521856929437	0.253626000368663	0.172442299171847	0.271797899610845	0.618454764709458	NA	NA	0.735310569985364	0.757242770109911	81.1189965339742
a7234	loss_cnaOV81_(RB1)	330	XMD13-2	RIPK	4	28	2.32630161961136	NA	3.83523428661526	4.11956332765229	-0.284329041037033	0.856863860590596	1.15132109298554	0.252658801538827	0.331825222318349	0.246958943746724	0.618470223347779	NA	NA	0.819985544630248	0.581279083443698	81.1189965339742
a7235	loss_cnaOV35	1262	UNC1215	LMBL3	5	28	0	NA	2.7403076808738	2.78757431590841	-0.0472666350346036	0.772343697444703	0.443780694409217	0.0948183101916665	0.0611989651640651	0.106508993361073	0.618547460943078	NA	NA	0.110364314759418	0.899967438631438	81.1189965339742
a7236	PTEN_mut	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	4.38084686305895	4.54948417426591	-0.168637311206956	0.618769342209328	1.04727801914924	0.164636140581181	0.272536629893189	0.161024396696447	0.618746847180995	NA	NA	0.192214197402624	0.703647536960058	81.1305340246944
a7237	gain_cnaOV49	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.30796279764003	0.593321514010106	-0.285358716370076	0.45966760863291	1.25773001878577	0.233982243845255	0.620793614800828	0.226883919527948	0.618806448328337	NA	NA	0.431862304464326	0.452745955120993	81.1305340246944
a7238	loss_cnaOV16, loss_cnaOV17	1262	UNC1215	LMBL3	6	27	0	NA	2.92694352894764	2.7478502991155	0.179093229832135	0.738128238299433	0.431068884852077	0.362767617443633	0.24263159237038	0.415463133910933	0.618905307669584	NA	NA	0.110367236359632	0.588219455138251	81.132284522514
a7239	loss_cnaOV84	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	6	25	3.68887945411394	NA	3.25640111020654	3.54558120412723	-0.289180093920692	0.829664850268642	1.16819479919782	0.258850495498742	0.348550494608825	0.247544411359533	0.61908395288237	NA	NA	0.727341777566402	0.497616721998764	81.1385963584714
a7240	TP53_mut	140	Vinorelbine	Microtubules	12	7	-2.74887219562247	NA	-3.63016853759352	-3.15879241524708	-0.471376122346443	2.09473452476933	0.946550517576917	0.265360558251069	0.225029051067152	0.497993623787902	0.619199904901715	NA	NA	0.682434450316829	0.511640666297564	81.1385963584714
a7241	loss_cnaOV33_(ZFHX3)	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	1.9820081656338	2.34535166982699	-0.36334350419319	1.66877623565218	1.2051750206755	0.288124961333238	0.217730511994731	0.30148608953871	0.619303370034185	NA	NA	0.844836713168188	0.699398814892122	81.1385963584714
a7242	MLL2_mut	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	1.97547524722418	2.59320153195818	-0.617726284734002	0.663391649973727	1.0479343582236	0.60120669648827	0.931163792547686	0.589470399444809	0.619335229448161	NA	NA	0.396040480904936	0.241709959474228	81.1385963584714
a7243	loss_cnaOV20	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.50192318435983	4.23646192591852	0.265461258441313	1.24383596547436	0.831797189655295	0.295702856974918	0.213421436435209	0.319141807333255	0.619664382925508	NA	NA	0.522383757826269	0.666996280781606	81.1385963584714
a7244	KRAS_mut	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.58059718715421	-2.2784914308636	-0.302105756290615	0.573610630501311	0.778344238894899	0.39901078761793	0.526673914719096	0.388139002248603	0.619731671878353	NA	NA	0.675389155355224	0.480566660379847	81.1385963584714
a7245	loss_cnaOV44	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-1.59827081441042	-2.02895596706975	0.430685152659329	2.15105747610827	2.03833438995117	0.210522219038748	0.200220197480976	0.211292688178433	0.619790812179151	NA	NA	0.279236629591372	0.766832182181706	81.1385963584714
a7246	TP53_mut	295	NVP-BHG712	EPHB4	22	10	2.32630161961136	NA	3.20103998832956	3.36132725204141	-0.16028726371185	1.05322443479482	1.18121730650098	0.146622499147104	0.152187186715883	0.135696677342678	0.619864064757421	NA	NA	0.0628808155464606	0.717923748906672	81.1385963584714
a7247	gain_cnaOV72_(ASXL1)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-2.37835258049549	-2.07808000475164	-0.300272575743852	1.41132099109963	1.28158899875195	0.231146606047997	0.212759944504117	0.234297092153777	0.619962373421179	NA	NA	0.608245716284874	0.674642837442804	81.1385963584714
a7248	gain_cnaOV18_(CCNE1)	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.09423549325305	3.63988652291992	0.454348970333124	0.897825515796066	1.25467841203305	0.370988847023912	0.506054865159708	0.362123844624781	0.619983042051132	NA	NA	0.199023698675427	0.411832285798859	81.1385963584714
a7249	gain_cnaOV51_(MYC)	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-3.16993078026504	-3.55885110403762	0.388920323772579	2.27399754065527	1.60248834778582	0.218079844597363	0.17102935109618	0.242697754595193	0.620070121982897	NA	NA	0.682446240683616	0.73762670251322	81.1385963584714
a7250	loss_cnaOV85	309	Y-39983	ROCK	7	25	2.99573227355399	NA	5.24393253044065	4.88598957461955	0.357942955821095	1.50635562481068	1.16140002485172	0.289105730458299	0.237621813817093	0.308199542071469	0.620071868064833	NA	NA	0.373549481465628	0.576319308295183	81.1385963584714
a7251	loss_cnaOV55	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-4.55524206257907	-4.02817541661791	-0.527066645961164	0.913827729395798	2.61438072373304	0.223741591923699	0.576768059237651	0.201602865709847	0.620307772173334	NA	NA	0.928200367308876	0.421194617219437	81.1385963584714
a7252	loss_cnaOV85	201	Epothilone B	Microtubules	6	13	-3.44201937618241	NA	-4.46639011127134	-4.74073108356008	0.274340972288744	2.7638925905677	1.7221249631206	0.131684236287837	0.0992589123126506	0.159303754468329	0.62032343836471	NA	NA	0.351471165569871	0.829355994200633	81.1385963584714
a7253	loss_cnaOV83	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-0.200928871269713	-0.649892679739371	0.448963808469658	1.22103865224604	1.54806667864865	0.300197565228224	0.36769008715966	0.290015807885983	0.620385485708583	NA	NA	0.909527536312313	0.561387947872654	81.1385963584714
a7254	loss_cnaOV56	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.34353508465874	2.09248986158847	0.251045223070276	0.734442380377199	0.544472722431488	0.449352992782339	0.341817451957692	0.461079522862352	0.620565074024334	NA	NA	0.0427064440118931	0.61731429318405	81.1385963584714
a7255	loss_cnaOV38	1059	AZD8055	MTORC1/2	8	25	0.693147180559945	NA	0.571476568543266	0.188211276175753	0.383265292367512	1.12330295108116	1.13901863049995	0.337533267306808	0.341194948342855	0.336487290115075	0.620630698160328	NA	NA	0.147580793006162	0.418909752106406	81.1385963584714
a7256	PIK3CA_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-3.46104995090532	-4.16867725131815	0.707627300412836	2.21025687909068	1.67190585149982	0.390304010007282	0.320156135292275	0.423245902140986	0.620672979438039	NA	NA	0.591753854058299	0.539462377623025	81.1385963584714
a7257	gain_cnaOV26	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.8755338996095	5.50390565040903	0.371628249200475	0.881924057218142	0.98896930669067	0.378364661851401	0.421383503668903	0.375773289106446	0.62072806637757	NA	NA	0.305158976735358	0.54950001280633	81.1385963584714
a7258	loss_cnaOV58	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.25269766951242	0.770866344867055	0.481831324645368	0.795973569552532	1.40798936682454	0.358302032683373	0.605335834098407	0.342212331995127	0.620759839149076	NA	NA	0.164117885299647	0.305629371138388	81.1385963584714
a7259	loss_cnaOV102	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.69327230477149	2.27473169976882	0.418540605002669	0.486933879642138	1.49597005082163	0.288508879172656	0.8595429944416	0.279778732717807	0.620991060872347	NA	NA	0.821304140359384	0.323320172974874	81.1385963584714
a7260	loss_cnaOV84	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.41747201726429	-4.73860604768483	0.321134030420548	3.08722050813255	1.65458325068318	0.154219185275899	0.104020438311613	0.194087562706772	0.620995528932017	NA	NA	0.351485398744126	0.833721976342346	81.1385963584714
a7261	gain_cnaOV4_(KRAS)	255	CP724714	ERBB2	8	24	2.32630161961136	NA	4.563372389941	4.3656352722094	0.1977371177316	0.645785110755397	1.02985496414708	0.207235116189324	0.306196464486924	0.192004820693722	0.62103686559826	NA	NA	0.786882667252935	0.531410282806378	81.1385963584714
a7262	loss_cnaOV33_(ZFHX3)	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	2.984421185915	3.26473918131557	-0.280317995400572	0.80315023889564	1.27661678222877	0.226528900551715	0.349023111523966	0.219578811200635	0.621042324094584	NA	NA	0.601669903553216	0.573486641371483	81.1385963584714
a7263	loss_cnaOV35	1009	ATRA	Retinoic acid and retinoid X receptor agonist	5	26	2.30258509299405	NA	4.2768429527305	4.55682284397717	-0.279979891246675	1.58745301770223	0.765724925681596	0.303137790411483	0.176370505535927	0.365640299612104	0.621091317343532	NA	NA	0.529296393356969	0.717693854915253	81.1385963584714
a7264	gain_cnaOV4_(KRAS)	150	Bicalutamide	ANDR (androgen receptor)	6	13	0.0237165266173161	NA	3.07531749856651	2.92978807039467	0.145529428171845	0.531686949269175	0.634390100285086	0.240150405276907	0.273712620503251	0.229400534633888	0.621249778010626	NA	NA	0.850083242370707	0.612248988780551	81.1481246519424
a7265	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.55280395373843	2.06172689739607	0.491077056342363	1.2464921884039	1.58815136354647	0.316443107503559	0.393967215286902	0.309213005519668	0.621340831397081	NA	NA	0.947908123825238	0.588072888898067	81.1488467433605
a7266	loss_cnaOV85	208	SB-715992	KIF11	7	25	-2.05572501506252	NA	-0.79865077418574	-1.46264857368628	0.663997799500539	2.04055161131647	1.81959883216386	0.355862365852819	0.32540112968383	0.364914390888522	0.621644633257972	NA	NA	0.0746959131515173	0.456502909401903	81.1534460323375
a7267	loss_cnaOV39	255	CP724714	ERBB2	9	23	2.32630161961136	NA	4.53016315917927	4.3700329226061	0.16013023657317	1.11347584793297	0.890944339285878	0.167611092288529	0.143811144956967	0.17973090967896	0.621647410081406	NA	NA	0.78688577876282	0.706267902663855	81.1534460323375
a7268	loss_cnaOV52, loss_cnaOV53	1010	Gefitinib	EGFR	8	22	-0.693147180559945	NA	1.12102085020846	0.854300606974751	0.266720243233714	1.51707558999938	1.18328578041146	0.209200164673676	0.175812098613901	0.225406446734253	0.621767737923926	NA	NA	0.957567643194072	0.662070052512679	81.1534460323375
a7269	loss_cnaOV41	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	2.07290448896127	1.47128595691644	0.601618532044829	1.24841760485961	1.66874783634595	0.371593981437202	0.481904876783984	0.360520936082345	0.621966543484252	NA	NA	0.0794136965325391	0.381501351189177	81.1534460323375
a7270	gain_cnaOV95_(MECOM)	266	Zibotentan, ZD4054	Endothelin A Receptor	9	23	2.99573227355399	NA	5.78605201065531	5.68729918370921	0.0987528269460993	0.462512117780054	0.485834829474418	0.205852426278848	0.213514031632488	0.203264197943427	0.621984980084276	NA	NA	0.382699410867379	0.600096056763576	81.1534460323375
a7271	loss_cnaOV38	223	ZSTK474	PI3K	8	24	1.63315443905142	2.32630161961136	0.938145822292817	0.69830392055882	0.239841901733997	0.839433144797315	1.10754313803031	0.228177710919646	0.285718884488303	0.216553101634072	0.622162539313456	NA	NA	0.772390362750297	0.529500258430082	81.1534460323375
a7272	gain_cnaOV96	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	0.411253350646434	0.0746400616011346	0.336613289045299	0.778726616840471	1.70401604738857	0.206157560026512	0.432261183534526	0.197541149662977	0.622172229842651	NA	NA	0.462832292173753	0.526417756153556	81.1534460323375
a7273	PIK3CA_mut	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	4.32396373768975	3.82096037022163	0.503003367468122	1.19297631724948	1.65116935107034	0.323360681566023	0.421637345348015	0.304634631900149	0.62220983236877	NA	NA	0.743998172862816	0.484330372199099	81.1534460323375
a7274	loss_cnaOV52, loss_cnaOV53	222	BX-912	PDPK1 (PDK1)	8	24	2.32630161961136	NA	3.30896987203541	3.44356629894508	-0.134596426909674	0.994123496162141	1.29322851515156	0.109431496920662	0.1353920588632	0.104077837236601	0.62222068183065	NA	NA	0.327741085012311	0.763496665282042	81.1534460323375
a7275	gain_cnaOV19	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	3.39993096898693	3.2357365295415	0.164194439445432	1.00375228295694	1.10098467453769	0.149980596134365	0.163580638603116	0.149134173474647	0.62231571486514	NA	NA	0.0628957388606947	0.809610646015009	81.1534460323375
a7276	SMAD4_mut	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.68788152273065	-4.11486795258876	0.426986429858108	1.34366537339663	1.55044172078227	0.279012774604829	0.317777356112657	0.275396633188297	0.622363004787519	NA	NA	0.864376379873186	0.590559636992668	81.1534460323375
a7277	loss_cnaOV84	282	EKB-569	EGFR	6	26	0.916290731874155	2.99573227355399	2.05125450056619	1.59876678839674	0.452487712169453	1.15520695606578	1.54275478366638	0.304663916762162	0.391694068143828	0.293298531276701	0.622422504909441	NA	NA	0.327429698310997	0.438827691569763	81.1534460323375
a7278	SMARCA4_mut	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	2.02188078098899	1.37011626896712	0.651764512021867	2.76448093497714	1.70069967491375	0.363216198414901	0.235763793403501	0.383233160819486	0.622499187167996	NA	NA	0.615401907916783	0.724998347474542	81.1534460323375
a7279	gain_cnaOV19	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.603091466226769	-1.39129294354403	0.78820147731726	0.972942655695156	1.92051432301189	0.420975282094181	0.810121205708778	0.410411663101344	0.622587088100435	NA	NA	0.0747022531688272	0.303433941957004	81.1534460323375
a7280	loss_cnaOV44	152	CP466722	ATM	3	29	2.77258872223978	NA	2.90390501770709	2.62033168507938	0.283573332627709	0.988765680412454	0.802403745677792	0.347451251462157	0.286795282487372	0.353404796718856	0.622658998485427	NA	NA	0.556740543726329	0.672977853780376	81.1534460323375
a7281	KRAS_mut	291	KIN001-266	MAP3K8 (COT)	7	25	2.99573227355399	NA	3.47784922148153	3.25332694406339	0.224522277418142	1.08915770754407	1.11763535323687	0.201908855255211	0.206143036828354	0.200890457489453	0.622821594893904	NA	NA	0.951028781247095	0.642190568136952	81.1601784380266
a7282	gain_cnaOV72_(ASXL1)	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-0.907749677435152	-0.461407131428587	-0.446342546006565	0.773559693583699	1.60881899020025	0.298415790336989	0.576998193815886	0.277434906428478	0.622881727985348	NA	NA	0.909537661614039	0.448511063800696	81.1601784380266
a7283	loss_cnaOV81_(RB1)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	2.44916904566613	2.87085173104165	-0.421682685375525	2.409752914424	1.44728960173418	0.26918910906358	0.174990009494944	0.291360267406229	0.623175267053629	NA	NA	0.968875019504946	0.753244392746685	81.1639314896202
a7284	gain_cnaOV94	255	CP724714	ERBB2	7	25	2.32630161961136	NA	4.5549637483261	4.37589917657084	0.179064571755265	0.525722080556487	1.03509348328906	0.187462446149786	0.340606906915003	0.172993622939522	0.623198506045855	NA	NA	0.786893652983052	0.539608198068453	81.1639314896202
a7285	gain_cnaOV94	269	NSC-207895	MDM4	6	25	2.99573227355399	NA	3.6362722251319	3.94465672941996	-0.308384504288059	2.44701847581844	1.35747829011881	0.192837183439136	0.126024591696193	0.227174538652157	0.623419703808086	NA	NA	0.716193869760691	0.776238785281969	81.1639314896202
a7286	loss_cnaOV39	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-4.41405210049543	-3.82831934075026	-0.585732759745177	2.34481950114863	1.62829679779995	0.321404904807133	0.249798655912854	0.35972112733783	0.62356829752783	NA	NA	0.591801661172771	0.626178921052656	81.1639314896202
a7287	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.15245001168995	2.39478074933219	-0.242330737642237	1.0966834486643	0.829750669252462	0.278513488731585	0.22096689608782	0.292052476270441	0.623576274737084	NA	NA	0.651250812574609	0.658707534685189	81.1639314896202
a7288	MLL2_mut	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.65084812617019	8.76016046552932	-0.10931233935913	1.31319550247906	1.23998707571544	0.0877887976943201	0.0832414816779145	0.0881560312199701	0.623719087881333	NA	NA	0.530821341208819	0.901156847574467	81.1639314896202
a7289	loss_cnaOV39	1001	AICAR	AAPK1 (AMPK) agonist	10	21	7.60090245954208	NA	8.96643639142536	8.64631778567038	0.320118605754981	1.32310440554149	1.19469742516396	0.259000598621967	0.241945083407057	0.267949523462854	0.623741117543954	NA	NA	0.530821567809167	0.525184370441442	81.1639314896202
a7290	loss_cnaOV83	1005	Cisplatin	DNA crosslinker	5	26	1.79175946922805	2.30258509299405	3.41446195969205	2.94839652173835	0.466065437953703	1.44427925852703	1.14348188172778	0.391815572542555	0.322697591343259	0.40758445358967	0.623940154234593	NA	NA	0.0892248545478765	0.525680305133016	81.1639314896202
a7291	loss_cnaOV42	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.373716664809	4.54959493666003	-0.175878271851023	1.89171005977786	0.8434881306875	0.176859646920564	0.0929731651750462	0.208513037056812	0.624228730876454	NA	NA	0.326490432911703	0.865570255736912	81.1639314896202
a7292	loss_cnaOV82	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.05590436278552	3.48405982092486	0.571844541860668	0.701189565908907	1.76663756436996	0.333524979267769	0.815534870544491	0.323690921892407	0.624294234853573	NA	NA	0.69916457928782	0.321570963725454	81.1639314896202
a7293	gain_cnaOV4_(KRAS)	211	TL-2-105	CRAF	8	24	2.32630161961136	1.63315443905142	4.50488346383258	4.37723900195956	0.127644461873028	0.733931492347481	0.601194092636699	0.201124433019877	0.173918769263814	0.212318223742367	0.624520828972953	NA	NA	0.272144716073289	0.665719281074375	81.1639314896202
a7294	PTEN_mut	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	0.71791403851347	2.17886731732125	-1.46095327880778	1.39488719879404	1.98928514889856	0.747180488556199	1.04736302696796	0.734411192692353	0.624587529186192	NA	NA	0.133241002672999	0.20018007274049	81.1639314896202
a7295	loss_cnaOV102	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	0.475988974691732	0.0797260050621849	0.396262969629547	1.45475800529251	1.64487203781766	0.242738035376508	0.272390987496144	0.240908083132892	0.624589300366928	NA	NA	0.462859325164073	0.692544496932615	81.1639314896202
a7296	NF1_mut	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	4.57153014043036	4.36089235323174	0.210637787198612	1.47702660499882	0.921250307634279	0.212560302519299	0.14260933857639	0.228643383294513	0.62477977144249	NA	NA	0.512379605284381	0.797617168093394	81.1639314896202
a7297	gain_cnaOV72_(ASXL1)	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	2.95044925242888	3.2814124280871	-0.330963175658217	1.22519321162546	1.23641750360003	0.268002256299337	0.270131414798757	0.267679141305073	0.624894428135158	NA	NA	0.601703892637292	0.600878253088433	81.1639314896202
a7298	loss_cnaOV33_(ZFHX3)	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	2.36443722675257	2.56085251011751	-0.196415283364932	1.18505622933921	1.02502623415285	0.188572889940266	0.165743429300781	0.191619762324682	0.624908329169235	NA	NA	0.39610195988534	0.769528194365869	81.1639314896202
a7299	loss_cnaOV87, loss_cnaOV88	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.3803884126332	-2.09889039931159	0.718501986678384	0.725904833012987	1.6030366167122	0.4610288725072	0.98980190515625	0.448213084584443	0.624986036078828	NA	NA	0.0382399642592008	0.228930337171718	81.1639314896202
a7300	loss_cnaOV21, loss_cnaOV22	292	Masitinib	KIT	3	29	2.99573227355399	NA	3.85180240181829	4.03024987057469	-0.178447468756401	0.469345514340544	1.08734304967651	0.168754207826687	0.38020490939842	0.164113311626437	0.625010793148222	NA	NA	0.105404876255308	0.62126397554827	81.1639314896202
a7301	gain_cnaOV72_(ASXL1)	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.62706925734442	4.4089945341135	0.218074723230917	1.00736717116314	1.01571617041401	0.214927594233679	0.216479878909614	0.214700454303123	0.625020883067184	NA	NA	0.375910948398231	0.672902971092266	81.1639314896202
a7302	loss_cnaOV87, loss_cnaOV88	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.79633879982496	3.53069452642713	0.265644273397827	1.52007034366531	0.911932828182494	0.275427559723381	0.174757881768343	0.291298070634504	0.625048756328012	NA	NA	0.729030398730128	0.792572979949751	81.1639314896202
a7303	loss_cnaOV81_(RB1)	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	3.2110571381623	3.43832577136843	-0.227268633206132	1.33262217369181	1.21692331401495	0.184924080573793	0.170542437078412	0.186756741849503	0.625105900729812	NA	NA	0.327774483045284	0.764295342918279	81.1639314896202
a7304	gain_cnaOV4_(KRAS)	266	Zibotentan, ZD4054	Endothelin A Receptor	8	24	2.99573227355399	NA	5.7879062331123	5.69079581067964	0.0971104224326576	0.494446668767739	0.475453062437883	0.202333554520093	0.196402218008013	0.204248179483216	0.625139268764611	NA	NA	0.382735463368413	0.636203948617655	81.1639314896202
a7305	gain_cnaOV96	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.24901214960094	5.02737355355715	0.221638596043797	0.683237240511453	0.606274023174572	0.359167007588224	0.324394782517833	0.365574950553304	0.625139302917565	NA	NA	0.111311609797344	0.526790928795652	81.1639314896202
a7306	loss_cnaOV36	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.78262021071582	1.26098861748236	0.521631593233467	1.09080781592003	1.22639823278557	0.428329226260657	0.478206688309711	0.42533622382076	0.625357095069128	NA	NA	0.098199562239286	0.501735673756729	81.1639314896202
a7307	loss_cnaOV55	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-1.8128542742336	-1.50811563861318	-0.304738635620425	0.238844898644241	1.45424727907517	0.23024920761068	1.27588505071792	0.209550768982166	0.625476528802393	NA	NA	0.623331567350604	0.450416491928424	81.1639314896202
a7308	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1003	Camptothecin	TOP1	8	23	-2.30258509299405	NA	-3.39623265056346	-3.79375408172992	0.397521431166462	2.2006716820968	1.55686497210364	0.2292130072777	0.180636409510983	0.255334559058984	0.625494226271761	NA	NA	0.246214993531765	0.647847969608464	81.1639314896202
a7309	loss_cnaOV1	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.890967100988463	0.613869195208685	0.277097905779778	0.366251061115212	0.630812980649116	0.449311588944019	0.756579120715807	0.439271090291516	0.625522973233905	NA	NA	0.0152972335656516	0.326031118567477	81.1639314896202
a7310	gain_cnaOV95_(MECOM)	1377	Afatinib (rescreen)	ERBB2, EGFR	8	25	2.30258509299405	NA	2.90717340147922	2.57444959805432	0.332723803424899	1.10835038558138	1.84965681833348	0.19450933865831	0.30019730922038	0.179884073697887	0.625525418418273	NA	NA	0.640735920615725	0.543811293513631	81.1639314896202
a7311	loss_cnaOV70	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.23570404183193	4.46266937054681	-0.226965328714877	0.45166459505942	1.04333284444137	0.223475501657078	0.502508567635279	0.217538755656064	0.625544913839865	NA	NA	0.375916718517809	0.516026839677804	81.1639314896202
a7312	gain_cnaOV94	265	Tubastatin A	HDAC6	6	25	2.99573227355399	NA	4.90736637458093	4.72001990192784	0.187346472653094	1.03743645310311	1.27355847717972	0.15156623504638	0.180585974295308	0.147104727431104	0.625592577439616	NA	NA	0.425897050580313	0.713398969862252	81.1639314896202
a7313	loss_cnaOV56	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	8.27672861596058	8.80902074466093	-0.532292128700345	1.90591495289048	1.70085304801418	0.310232915020045	0.279284302740308	0.312955977779397	0.625658252793303	NA	NA	0.92196859453086	0.68187140148961	81.1639314896202
a7314	gain_cnaOV72_(ASXL1)	326	GSK690693	AKT	5	27	2.32630161961136	NA	4.33939191932491	4.1172161911987	0.222175728126208	1.9670334370083	1.37477326727502	0.151385439402293	0.112949644854091	0.161608996490447	0.625726322924259	NA	NA	0.0942398186403707	0.81897940110641	81.1639314896202
a7315	gain_cnaOV95_(MECOM)	1053	MK-2206	AKT1, AKT2	8	24	1.38629436111989	0.693147180559945	1.51950851267516	1.24001926823894	0.279489244436228	0.996882215287167	1.28211548988026	0.228802052124258	0.280363357024799	0.217990693227122	0.625733389003328	NA	NA	0.0982024782556351	0.533683428029772	81.1639314896202
a7316	loss_cnaOV1	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.38291241323181	5.11756258028697	0.265349832944843	0.454788337993891	0.594466928085658	0.45266756065491	0.583457865510192	0.446366013664277	0.625822487153509	NA	NA	0.0120529077395449	0.425558141078645	81.1643928075392
a7317	gain_cnaOV19	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.98714295605291	3.64982860896564	0.337314347087266	0.415226554411718	1.08824343293542	0.319186065925768	0.812362175548151	0.309962216980621	0.6259823153223	NA	NA	0.83134490014973	0.325797848885108	81.1740258884426
a7318	gain_cnaOV50	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	5.38324391069879	5.56096035421054	-0.177716443511753	0.660765336190179	1.0164639989575	0.180115322618853	0.268955457827774	0.174837912305818	0.626184752315808	NA	NA	0.305222074088897	0.660387175866896	81.1891808652427
a7319	loss_cnaOV52, loss_cnaOV53	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	2.0460524149667	1.79454944856933	0.251502966397372	0.874190483348049	1.86355981270334	0.149357227761152	0.287698128941126	0.134958354801896	0.626388842618356	NA	NA	0.347728426661619	0.696732070705424	81.193870942786
a7320	gain_cnaOV18_(CCNE1)	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.90210079925963	2.37358793163436	0.528512867625273	0.333926006093818	1.53404037183304	0.362207365170168	1.58272448979845	0.344523441057648	0.626475427980347	NA	NA	0.241126009049388	0.127215519761804	81.193870942786
a7321	gain_cnaOV51_(MYC)	1194	SB-505124	TGFR1 (ALK5)	8	24	2.30258509299405	NA	4.7238781708271	4.54329020036367	0.180587970463425	0.599949789812521	1.03184836535648	0.190328478468396	0.301005139979893	0.175014058776975	0.626477643362846	NA	NA	0.943265298659332	0.552138443069691	81.193870942786
a7322	loss_cnaOV40	226	GSK1070916	AURKB	7	25	0.940007258491471	2.32630161961136	2.52865517291347	2.25385799988864	0.274797173024839	0.85955121504031	1.56480129835914	0.18932861521594	0.319698428920204	0.175611544617833	0.626705007090373	NA	NA	0.821328527264528	0.549878528967657	81.1994364737508
a7323	loss_cnaOV52, loss_cnaOV53	309	Y-39983	ROCK	8	24	2.99573227355399	NA	5.22253710980782	4.87820709167128	0.344330018136533	1.55874348354339	1.1222758295424	0.278143119748768	0.220902298403704	0.306814072862044	0.626840479870506	NA	NA	0.373627166127335	0.577333908278502	81.1994364737508
a7324	loss_cnaOV83	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.68849580265182	2.80744623140331	-0.118950428751485	1.34090101778223	1.22150241310647	0.0960759319359591	0.088709328409805	0.0973804287860358	0.626990280654526	NA	NA	0.0954757970964166	0.860337156648473	81.1994364737508
a7325	loss_cnaOV43_(NF1)	1001	AICAR	AAPK1 (AMPK) agonist	5	26	7.60090245954208	NA	9.05969220195006	8.68994524629159	0.369746955658469	1.17864922240432	1.24684417866301	0.298746456231486	0.313703983025775	0.296546242093336	0.627070746725435	NA	NA	0.530855611414703	0.548580995111396	81.1994364737508
a7326	loss_cnaOV39	229	LY317615	PRKCB (PKCbeta)	9	23	2.99573227355399	2.32630161961136	2.63531032292715	2.79351337123846	-0.158203048311308	1.79855751918898	1.6518655917158	0.0934880634587554	0.0879610724836016	0.0957723492181845	0.627469616707475	NA	NA	0.322360853319674	0.822418749084154	81.1994364737508
a7327	loss_cnaOV43_(NF1)	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	2.07903744940101	1.6103806020262	0.468656847374812	1.37829105090096	1.50189122054041	0.315380332421049	0.34002749061489	0.312044468311214	0.627602373521005	NA	NA	0.327489370248526	0.517303707981677	81.1994364737508
a7328	loss_cnaOV84	1262	UNC1215	LMBL3	6	27	0	NA	2.9247149225868	2.74834554497346	0.17636937761334	0.701760303505808	0.442801915734781	0.357137918585625	0.251324243808385	0.398303104268811	0.627851905517487	NA	NA	0.110439092964574	0.576976443569151	81.1994364737508
a7329	loss_cnaOV58	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	2.30258509299405	NA	1.86302591553895	2.22517827642351	-0.362152360884566	1.60193600989367	1.25200828926968	0.277328416779579	0.226071677425246	0.289257159068664	0.6280425614491	NA	NA	0.687211568517853	0.652743844358755	81.1994364737508
a7330	loss_cnaOV84	294	MPS-1-IN-1	MPS1	6	25	2.99573227355399	NA	4.08109194293413	4.33251101385147	-0.251419070917335	0.79054762796545	0.825528934189831	0.306756689493064	0.318031529060919	0.304555128844849	0.628125006790037	NA	NA	0.317966173018646	0.507979645732841	81.1994364737508
a7331	loss_cnaOV43_(NF1)	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.73730196620237	3.06284835690508	-0.325546390702715	1.27797426864041	1.05094818524539	0.300328122742736	0.254736264016529	0.309764453921867	0.628158236403187	NA	NA	0.435544998049645	0.614080073827785	81.1994364737508
a7332	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	0.867585031734211	1.27828693335207	-0.410701901617863	1.45818583713223	1.20373048509068	0.331344236251462	0.281652647529191	0.341190911673991	0.62818987403064	NA	NA	0.267958073271419	0.577854873606133	81.1994364737508
a7333	loss_cnaOV83	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	4.0619902539512	3.72323619731227	0.338754056638933	0.656570397492464	1.02311428462911	0.343987552326163	0.515944760733477	0.331100896281333	0.628213302837255	NA	NA	0.808717951333367	0.501676440699889	81.1994364737508
a7334	loss_cnaOV42	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	1.96883162163495	1.70592043187422	0.262911189760735	1.75063941423661	1.70832684018503	0.153527714091878	0.150180092840753	0.15389981798346	0.628313057752916	NA	NA	0.230249039969027	0.792235599255013	81.1994364737508
a7335	loss_cnaOV59	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.41176442128151	4.26489886365798	0.146865557623535	0.55337946770479	0.850176695908742	0.178139057551657	0.265397554832813	0.172747098726992	0.628327899686572	NA	NA	0.317968565451917	0.665581714139523	81.1994364737508
a7336	ARID1A_mut	1050	ZM-447439	AURKB	7	15	1.38629436111989	0.693147180559945	1.81817041295439	2.74258547878273	-0.924415065828339	1.17374557304211	1.66745030413871	0.601796892952673	0.787577041447276	0.5543883757938	0.628382806850872	NA	NA	0.228999312046842	0.153829777633555	81.1994364737508
a7337	SMAD4_mut	308	XL-880	MET	3	29	1.63315443905142	NA	0.454420637608033	0.23227196240847	0.222148675199564	0.409727882079912	1.00521162801337	0.227408177655596	0.542185887062079	0.220996921452852	0.628511963815428	NA	NA	0.369346948007468	0.493343459738083	81.1994364737508
a7338	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.17990774648729	2.86829855102942	0.311609195457867	0.910035782652649	0.843741275781218	0.365084069051885	0.342414223042486	0.369318420708231	0.628524537153497	NA	NA	0.331452782845654	0.561532109995465	81.1994364737508
a7339	ARID1A_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	8	23	2.32630161961136	NA	2.31280143443365	2.28722606478317	0.0255753696504795	1.44135348504303	1.41713627854898	0.0179726060193823	0.01774399542921	0.0180472196200258	0.628548058908728	NA	NA	0.530870803775582	0.966079825041741	81.1994364737508
a7340	gain_cnaOV95_(MECOM)	1264	SGC0946	Q8TEK3 (DOT1L)	8	25	-0.693147180559945	NA	2.20985381473463	2.08505882335013	0.124794991384497	0.494611216207627	0.578823932511298	0.222484919952678	0.25230926290218	0.215600952854625	0.62857572458746	NA	NA	0.0427428119039941	0.561494809183177	81.1994364737508
a7341	loss_cnaOV20	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.06376264613533	4.32617360666211	-0.262410960526779	0.422781988335916	0.8667848284042	0.320027506509169	0.620676773766161	0.302740601736064	0.628644102697236	NA	NA	0.317972290518934	0.322654154871582	81.1994364737508
a7342	loss_cnaOV84	292	Masitinib	KIT	6	26	2.99573227355399	NA	4.30911771226726	3.94530566071221	0.36381205155505	0.959275723275996	1.06556391910352	0.346951044678516	0.37925701936103	0.341426774154602	0.628791218807716	NA	NA	0.105435138849489	0.435836496041957	81.1994364737508
a7343	loss_cnaOV59	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	9.13940915744299	8.70093074328206	0.438478414160922	2.10161961399655	1.66665099105653	0.255409541060222	0.208638333616942	0.263089522949829	0.628852611666857	NA	NA	0.921974778870172	0.71245578985112	81.1994364737508
a7344	gain_cnaOV94	1039	SL 0101-1	RSK, AURKB, PIM3	7	26	2.30258509299405	NA	5.0670671283385	4.9028234892162	0.164243639122307	0.999026676215308	0.774321420222537	0.199659881426286	0.164403657112065	0.212112999631476	0.62886790080148	NA	NA	0.946094268249323	0.697048340847853	81.1994364737508
a7345	loss_cnaOV33_(ZFHX3)	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	4.65577339675553	4.81497031303264	-0.159196916277113	0.78454573779596	0.653200889455993	0.238497463413733	0.202916042504225	0.24371815600205	0.629010589333295	NA	NA	0.762611834442215	0.720338272374084	81.1994364737508
a7346	loss_cnaOV1	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-2.16799192383554	-2.01450430882562	-0.153487615009913	1.7868899697915	1.55617716174582	0.0975655044538454	0.0858965115954076	0.0986311962307175	0.629084470296522	NA	NA	0.0382582322633139	0.897635402244692	81.1994364737508
a7347	gain_cnaOV19	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.09881928322136	4.83536504946443	0.263454233756926	0.594567022042788	0.622269272102777	0.424610508658856	0.443102667974691	0.423376575974352	0.62915350674675	NA	NA	0.0501373970997652	0.529611579512208	81.1994364737508
a7348	loss_cnaOV34	1016	Temsirolimus	MTOR	5	26	-1.6094379124341	NA	-2.06591133370967	-2.02232845192599	-0.0435828817836761	0.755279583572766	1.66787998971205	0.0276929950499822	0.0577043027927646	0.0261307060774801	0.629510449094458	NA	NA	0.0382601159438367	0.927544336139985	81.1994364737508
a7349	loss_cnaOV39	157	JNK-9L	JNK	5	14	1.63315443905142	NA	-0.320330755472055	0.0716544589220694	-0.391985214394125	1.38616893393265	0.853119644521052	0.390296497163491	0.28278314770916	0.459472732707015	0.629521831826962	NA	NA	0.192229494424176	0.578092227187875	81.1994364737508
a7350	gain_cnaOV94	256	JW-7-24-1	LCK	7	25	2.32630161961136	NA	2.17654718500387	1.87292737217619	0.303619812827675	1.03180601105839	1.41459937981885	0.225442434915373	0.294260558257685	0.214633073617321	0.629646012741262	NA	NA	0.839408137833379	0.539439491336933	81.1994364737508
a7351	loss_cnaOV82	219	AT-7519	CDK9	3	29	2.32630161961136	NA	2.06899063726548	1.43860947179847	0.630381165467018	1.1905659378062	1.73933999650562	0.369021917643546	0.529480262662806	0.362425498599163	0.629651677082119	NA	NA	0.317193680024676	0.467959717923146	81.1994364737508
a7352	loss_cnaOV57_(ZNRF3)	308	XL-880	MET	4	28	1.63315443905142	NA	0.414051989857854	0.230105030829939	0.183946959027915	0.492148719424457	1.01684838410245	0.188250260848146	0.373762953692192	0.180899101482352	0.62983342263027	NA	NA	0.369361829582304	0.573141724093845	81.1994364737508
a7353	loss_cnaOV41	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	3.16260170008451	2.71964884298985	0.442952857094658	0.260256236552024	1.31480977549034	0.360797510779318	1.7019874834243	0.336895013523508	0.629843846444664	NA	NA	0.0954973565666939	0.122387452868654	81.1994364737508
a7354	gain_cnaOV95_(MECOM)	279	BIX02189	MAP2K5 (MEK5)	9	23	2.99573227355399	NA	4.32468107243792	4.47285769704929	-0.148176624611377	0.533001082923174	0.803059309862889	0.200040208382443	0.278004359388394	0.184515169417158	0.629979759404779	NA	NA	0.525290945814371	0.550064338588279	81.1994364737508
a7355	loss_cnaOV35	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.33576186030141	3.58300430462577	-0.247242444324362	0.925496897633956	0.903973587045214	0.272631865733856	0.267145621942591	0.273506270390614	0.630026569980954	NA	NA	0.663989015864105	0.603429701529076	81.1994364737508
a7356	loss_cnaOV83	164	JQ12	HDAC	4	15	1.63315443905142	NA	1.22390089600117	1.94589096718931	-0.721990071188135	2.81160537080124	2.0744678532548	0.324871166362055	0.256789263061617	0.348036278342587	0.630072578686517	NA	NA	0.661677057131584	0.656850733944059	81.1994364737508
a7357	loss_cnaOV57_(ZNRF3)	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	4.693014432498	4.25477006079962	0.438244371698385	1.59089506363945	1.27890614065745	0.333940111773226	0.275470319642469	0.342671254571579	0.630087884679378	NA	NA	0.372128284043976	0.628764741985944	81.1994364737508
a7358	loss_cnaOV85	1007	Docetaxel	Microtubules	7	24	-4.38202663467388	NA	-4.26055393512396	-4.76174779182995	0.501193856705986	1.6714223054441	1.34219247850508	0.353800369449104	0.299860696529843	0.373414293950008	0.630196300981055	NA	NA	0.136323965612001	0.486511733061782	81.1994364737508
a7359	gain_cnaOV94	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-1.65431750373505	-2.26952964975806	0.615212146023006	1.24485349222217	2.82214103925801	0.229120227608855	0.494204458489971	0.21799482643318	0.630276890557511	NA	NA	0.418724032445344	0.560977848903564	81.1994364737508
a7360	NF1_mut	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.58294589055774	2.32996285274484	0.252983037812904	0.668193565113889	0.893508316697957	0.289588194761572	0.378607414110288	0.283134508191067	0.630278130654578	NA	NA	0.608733976945125	0.531012138445388	81.1994364737508
a7361	gain_cnaOV51_(MYC)	303	PIK-93	PI4K, PI3K	8	24	2.99573227355399	NA	2.62337399618211	2.9993059092948	-0.375931913112684	1.12457020477676	1.28158909653707	0.301536412622453	0.334289412538108	0.293332640023603	0.630305136505199	NA	NA	0.232637819004148	0.443159414297375	81.1994364737508
a7362	gain_cnaOV94	151	QS11	ARFGAP	3	16	2.32630161961136	NA	3.62895169045059	3.79262218617133	-0.163670495720742	0.943554781197301	1.53428708512093	0.110805098314751	0.173461572112492	0.106675274339445	0.63043426682756	NA	NA	0.0656281148087565	0.817150166982403	81.1994364737508
a7363	loss_cnaOV38	1161	ZG-10	IRAK1	7	16	2.30258509299405	NA	1.90482698931974	1.4344660166282	0.470360972691547	1.4332055683307	1.17125647832127	0.375776095305012	0.328188072308003	0.40158665620847	0.630572387201002	NA	NA	0.165224740805467	0.463153368114277	81.1994364737508
a7364	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.497808946196372	-0.84946645018874	0.351657503992368	0.854802009578245	0.802591128622691	0.436137067730844	0.411390591098252	0.438152742350691	0.630743554197667	NA	NA	0.0794296658803213	0.555760516986529	81.1994364737508
a7365	loss_cnaOV59	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.656090544584221	0.229404561186313	0.426685983397908	1.42661981986537	1.10379121672522	0.374601879333649	0.299088781367256	0.38656403215802	0.630751727172226	NA	NA	0.147673146135657	0.600134571922131	81.1994364737508
a7366	gain_cnaOV26	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.83812858820254	4.56260704864611	0.275521539556433	0.865695982408275	0.954282814675493	0.290440164432781	0.318265933024156	0.288721053464768	0.630892020157305	NA	NA	0.943271273294705	0.645311170680139	81.1994364737508
a7367	loss_cnaOV44	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.99830985942394	4.79246751670972	0.205842342714224	0.644489576050789	0.757888092908596	0.274141673298115	0.319388164468935	0.271599916452374	0.630921452574422	NA	NA	0.765730719111798	0.645475536470021	81.1994364737508
a7368	loss_cnaOV85	1129	PF-4708671	RPS6KB1 (p70S6KA)	7	25	2.30258509299405	NA	4.47252706028474	4.11989217696383	0.352634883320908	1.10243418928777	0.934261059554378	0.363454751969972	0.319869328026492	0.377447908927198	0.63112487540682	NA	NA	0.0486191391668534	0.460756923337307	81.1994364737508
a7369	loss_cnaOV44	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.62237259122175	2.36986034437182	0.252512246849927	1.29903942894948	0.917056409419815	0.266552644636714	0.19438382024642	0.2753508336632	0.631149922345503	NA	NA	0.735388786438924	0.771186247765293	81.1994364737508
a7370	SMAD4_mut	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	2.62097986572759	3.05006636398181	-0.429086498254221	0.967931183998193	1.66829843992825	0.263083329530456	0.44330269067457	0.257200083620934	0.631171193325378	NA	NA	0.664177917674577	0.544765529672114	81.1994364737508
a7371	PIK3CA_mut	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	2.26278028493377	2.3309947514986	-0.0682144665648341	0.856977646945895	1.34236260337232	0.0547778454662979	0.0795988866313345	0.0508167214979499	0.631192654308401	NA	NA	0.391094410394	0.898880185363495	81.1994364737508
a7372	loss_cnaOV21, loss_cnaOV22	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.22416025972102	0.832538070282542	0.391622189438475	1.90601971078046	1.19057842973211	0.313030151856844	0.205465970379769	0.328934389922212	0.631305132973935	NA	NA	0.845245222780648	0.758208532454175	81.1994364737508
a7373	loss_cnaOV36	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.45867058932742	1.84457871502833	0.614091874299087	1.04732205892013	1.39889874337761	0.445341323322367	0.586344829719581	0.438982361808673	0.631330245939605	NA	NA	0.0346381904162015	0.423645711987982	81.1994364737508
a7374	gain_cnaOV50	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.40105557031775	1.60410392401681	-0.203048353699058	0.655982377675731	1.31811780607711	0.159878275324005	0.309533244503452	0.154044162640785	0.631330946216927	NA	NA	0.165235320260145	0.689923949660535	81.1994364737508
a7375	loss_cnaOV55	1028	VX-702	p38	7	24	0.693147180559945	NA	3.52240437542959	3.26996730177756	0.252437073652028	1.14751153639141	0.860446046253274	0.272269147084024	0.219986523574195	0.293379317333423	0.631489582417141	NA	NA	0.519075796932308	0.604117047380436	81.1994364737508
a7376	loss_cnaOV59	305	TPCA-1	IKK	4	28	2.99573227355399	NA	3.60654071259326	3.28500276841102	0.321537944182231	1.67945985226415	1.17623845639502	0.260182651986898	0.191453188802788	0.27336119001558	0.631496591778988	NA	NA	0.993626288160492	0.732944449151421	81.1994364737508
a7377	gain_cnaOV95_(MECOM)	305	TPCA-1	IKK	9	23	2.99573227355399	NA	3.15305029454658	3.39255598760706	-0.239505693060479	1.29756209083892	1.21241119891332	0.193823136605482	0.184581296534048	0.197544936301435	0.631575960016553	NA	NA	0.993626300126667	0.640077103618182	81.1994364737508
a7378	gain_cnaOV94	341	EX-527	SIRT1	6	25	2.99573227355399	NA	5.9321359943846	5.73519578717107	0.196940207213532	0.549225584519155	0.566623006735763	0.349394300795787	0.358577991930133	0.347568321216037	0.631697615417998	NA	NA	0.111479845703941	0.456313460572881	81.1994364737508
a7379	loss_cnaOV70	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	1.76797108003688	1.91364866595739	-0.145677585920506	1.20625705910948	1.40202892998291	0.104786629440593	0.120768276397117	0.103904835916818	0.631748436491086	NA	NA	0.0346397960112453	0.858801868623782	81.1994364737508
a7380	loss_cnaOV54	257	NPK76-II-72-1	PLK3	10	22	2.32630161961136	NA	3.1201539206478	3.27949284609173	-0.159338925443923	1.01765906839828	1.32230349375873	0.128623435032958	0.156573974911569	0.120501024307962	0.631799478515291	NA	NA	0.601763651928357	0.713062854492166	81.1994364737508
a7381	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	4.04577629611165	3.48514497092563	0.56063132518602	1.48564308045614	1.73066777870503	0.326918966425204	0.377366093216608	0.323939309487528	0.631822608868674	NA	NA	0.699217909348333	0.590236450845079	81.1994364737508
a7382	loss_cnaOV54	273	CUDC-101	HDAC, EGFR	10	21	1.63315443905142	NA	-0.166161909153068	0.253424483683193	-0.419586392836262	1.39222746011272	1.71860618717457	0.258310427126736	0.301377759638708	0.244143420387698	0.631852706617945	NA	NA	0.462939161065039	0.475908887296716	81.1994364737508
a7383	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	8	25	0.693147180559945	NA	1.96329410824577	1.66562664579704	0.297667462448728	1.45401298999192	1.77735483493339	0.174105521636381	0.204721322641265	0.167477791490006	0.631878992995065	NA	NA	0.230286308875872	0.641061113918854	81.1994364737508
a7384	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	0	NA	-1.71582689478511	-2.07747505188171	0.361648157096604	2.30678207136677	1.960102201472	0.176972099669431	0.156776039481843	0.18450474512248	0.631912034856745	NA	NA	0.279369918224333	0.697459050614922	81.1994364737508
a7385	KRAS_mut	1058	GDC0941	PI3K (class 1)	7	26	1.38629436111989	0.693147180559945	0.50867003478593	0.934117529243774	-0.425447494457845	0.992070952581282	1.41621242330554	0.316411247280443	0.428847849391082	0.300412203322451	0.632083475378838	NA	NA	0.164225503123377	0.377987463071072	81.2063918108806
a7386	KRAS_mut	282	EKB-569	EGFR	7	25	0.916290731874155	2.99573227355399	1.78888260921025	1.65413140948963	0.13475119972062	1.05964793435019	1.5855668376564	0.0901191902709856	0.127166009909937	0.0849861365161963	0.632207184697961	NA	NA	0.327541493963093	0.795672964448007	81.2063918108806
a7387	gain_cnaOV48_(SOX17)	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.79758456863931	-4.07933241904991	-0.718252149589408	1.58396922498113	2.4056043345744	0.304804420713817	0.453450823577688	0.298574515877933	0.632222920483977	NA	NA	0.92822248191611	0.531852028939284	81.2063918108806
a7388	gain_cnaOV19	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.27482194395392	3.584644546	-0.309822602046078	0.403580515177098	0.991243006335107	0.321631466845488	0.767684737976318	0.312559685229534	0.632561048273062	NA	NA	0.729077012315201	0.343403719517583	81.2384757603358
a7389	loss_cnaOV1	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	1.8483341757303	1.38871054810198	0.45962362762832	1.62536578920792	1.8122418904171	0.255349740049429	0.282781654862015	0.253621566778005	0.632703558736248	NA	NA	0.615491140798376	0.681583521455219	81.2384757603358
a7390	gain_cnaOV51_(MYC)	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.23774517285291	-1.16469760752629	-0.073047565326628	1.13038269283754	1.37659609068665	0.0543433166904622	0.0646219778394348	0.0530639058332584	0.632729565434497	NA	NA	0.0499799081292563	0.91448976175111	81.2384757603358
a7391	loss_cnaOV52, loss_cnaOV53	1036	PLX4720	BRAF	9	24	2.30258509299405	NA	4.57067138469129	4.20934779295663	0.361323591734656	1.2081723050702	1.34379083755352	0.275790660853602	0.299066275744222	0.268883803667299	0.632894898571138	NA	NA	0.372158554096715	0.469148213413559	81.2453304254592
a7392	loss_cnaOV38	1016	Temsirolimus	MTOR	8	23	-1.6094379124341	NA	-1.56686302193182	-2.19022574970302	0.623362727771209	1.03201539961317	1.67973941051159	0.402584509008179	0.604024637621555	0.371106806133312	0.633009696261869	NA	NA	0.038275483096379	0.231817024020383	81.2453304254592
a7393	loss_cnaOV33_(ZFHX3)	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	3.97447201592041	3.47494444483596	0.499527571084454	0.59523338282015	1.79961969873918	0.291317897335942	0.839212963355226	0.277573962673572	0.633039834071639	NA	NA	0.699226396368104	0.292825861966473	81.2453304254592
a7394	loss_cnaOV84	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-3.0623102508976	-2.63474900087115	-0.427561250026448	1.41266538704812	1.16451040212455	0.348340932333145	0.302662791873079	0.367159665767176	0.63317561498849	NA	NA	0.380855584707	0.565794570734416	81.251766397692
a7395	loss_cnaOV33_(ZFHX3)	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.2485496251199	2.46695238508289	-0.21840275996299	2.95641873748899	1.19354020651883	0.148737711993786	0.0738740954363213	0.182987350380094	0.633432811420831	NA	NA	0.241202050385666	0.892749569148444	81.2707172608436
a7396	PIK3R1_mut	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	2.69350367125733	2.72020849512705	-0.0267048238697241	0.250285035326902	0.608757624718147	0.0465205009772549	0.106697645086309	0.0438677443787063	0.633494601895958	NA	NA	0.136489304216757	0.871316733940394	81.2707172608436
a7397	PTEN_mut	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	-0.402147535539237	0.37536843430679	-0.777515969846027	0.782880293902254	1.14791616271888	0.695569411438234	0.993147963873903	0.677328183971597	0.633788926494007	NA	NA	0.147700216007347	0.141583890911116	81.2903480584802
a7398	gain_cnaOV50	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	3.70094306004153	3.93245762386236	-0.231514563820831	2.20260808030741	1.66416067796671	0.134004560024614	0.105109286527506	0.139117915046339	0.633850703981696	NA	NA	0.148236976807886	0.851128971624258	81.2903480584802
a7399	loss_cnaOV102	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.63714796949368	4.8730783981645	-0.235930428670822	1.42414214616113	0.855993306537215	0.260213916681615	0.165664943844818	0.27562181487755	0.633908460506679	NA	NA	0.666126323531463	0.803024028194962	81.2903480584802
a7400	KRAS_mut	158	PF-562271	FAK	3	15	0.940007258491471	NA	2.01733379375565	2.34386104083133	-0.326527247075683	1.69887879000155	1.36143756290767	0.231900786107394	0.192201614969473	0.239840045531216	0.63400165145922	NA	NA	0.748013322260935	0.777907438381255	81.2903480584802
a7401	loss_cnaOV39	346	THZ-2-102-1	CDK7	9	23	0.916290731874155	2.99573227355399	-1.42627107743852	-0.915867100136999	-0.510403977301525	2.22944409808181	1.87449173684694	0.258381126098297	0.228937777691161	0.27228926501435	0.634075993230737	NA	NA	0.444655391578891	0.554004178038724	81.2903480584802
a7402	loss_cnaOV33_(ZFHX3)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.67165872158021	4.48796199336067	0.183696728219537	1.70041662423704	0.791184854436731	0.198047320589658	0.108030423603957	0.232179277939183	0.634354548778624	NA	NA	0.529431174252911	0.84443240651552	81.2995750735019
a7403	loss_cnaOV85	1059	AZD8055	MTORC1/2	7	26	0.693147180559945	NA	0.580308144970071	0.20057451684421	0.379733628125861	1.14783636453684	1.13418171024193	0.334026348923613	0.330825577458582	0.334808456790279	0.634391522880404	NA	NA	0.147705551845227	0.455185556497153	81.2995750735019
a7404	PTEN_mut	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.46235460631065	5.5466483359227	-0.0842937296120585	0.478436889397079	1.01488258470226	0.0852984487185106	0.176185681915716	0.0830576175832085	0.634512763772079	NA	NA	0.305316024386626	0.812757208905699	81.2995750735019
a7405	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	0.486709076846196	0.0497092942945044	0.436999782551692	2.46910144958647	1.10267628266634	0.326621734908246	0.176987374344169	0.396308317700457	0.634572812188609	NA	NA	0.870430997942821	0.790048668106703	81.2995750735019
a7406	gain_cnaOV26	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	1.66887015785291	1.08495967868047	0.583910479172441	2.1928836752997	1.48670128453982	0.368122644848525	0.266275172618374	0.392755750764808	0.634576385688306	NA	NA	0.536232013238431	0.695464624241096	81.2995750735019
a7407	gain_cnaOV72_(ASXL1)	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-4.66918742971582	-4.07146074236162	-0.597726687354201	1.04385197717269	2.46871306886266	0.253531271584589	0.572616329159202	0.242120761174394	0.634840240222324	NA	NA	0.928227213162585	0.421673617991388	81.3164156465819
a7408	loss_cnaOV84	345	KIN001-270	CDK9	6	26	2.99573227355399	NA	5.10697239491111	5.21014403500743	-0.103171640096315	0.796459366775651	0.772561992857457	0.132851116598988	0.129537857673757	0.13354480423599	0.634879236920455	NA	NA	0.334744953358077	0.781599258288638	81.3164156465819
a7409	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	3.12914624100439	2.88216879550065	0.246977445503744	1.49258366559904	1.23716164200794	0.196668302949062	0.165469749667011	0.199632317328311	0.635329965715819	NA	NA	0.232691734633189	0.804835645660568	81.3528398746455
a7410	gain_cnaOV4_(KRAS)	1039	SL 0101-1	RSK, AURKB, PIM3	7	26	2.30258509299405	NA	4.8030712788649	4.9738992948437	-0.170828015978808	1.19934263909691	0.702423319979027	0.207724315161104	0.142434705821382	0.243198098810143	0.635335100131995	NA	NA	0.946102206035201	0.728849223344857	81.3528398746455
a7411	loss_cnaOV39	223	ZSTK474	PI3K	9	23	1.63315443905142	2.32630161961136	0.919571595167713	0.695144187619339	0.224427407548374	0.784785061923394	1.13293175118796	0.213450638778301	0.285973087966704	0.198094375334654	0.635820303361816	NA	NA	0.772462417191178	0.531111891575555	81.4039830658061
a7412	ARID1A_mut	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	3.28320981774987	3.76732367372841	-0.484113855978544	1.04469438054265	2.24853701398955	0.238192023582259	0.46340237393359	0.215301706383559	0.63622320499814	NA	NA	0.747994911553206	0.418630883262474	81.4274077672798
a7413	gain_cnaOV96	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	0.848094816450132	0.601282736361726	0.246812080088406	0.509272709928783	0.630155951368013	0.401052021967436	0.484636375121927	0.391668252204234	0.636283260917674	NA	NA	0.0153208154587695	0.372969990250815	81.4274077672798
a7414	MLL2_mut	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-1.53299386798869	-0.738553779996707	-0.79444008799198	0.0421095381826747	0.804497979972696	1.02331477666118	18.8660365864292	0.987497927613121	0.636304340840979	NA	NA	0.0794681643249874	1.76554777821517e-05	81.4274077672798
a7415	TP53_mut	1375	Temozolomide	DNA akylating agent	23	10	3.40119738166216	NA	5.98544996815298	5.85929912271293	0.126150845440053	0.755884037621429	0.564773949740931	0.178746712045192	0.166891797102922	0.223365198585948	0.636468232476361	NA	NA	0.908910839199751	0.601503115070852	81.4274077672798
a7416	PIK3CA_mut	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.92578404997758	-1.44601653044601	-0.479767519531566	0.993220833700203	1.39444287430817	0.365918978138438	0.483042142545694	0.344056775914606	0.636532583204677	NA	NA	0.623497540624354	0.427144008855626	81.4274077672798
a7417	loss_cnaOV35	1005	Cisplatin	DNA crosslinker	5	26	1.79175946922805	2.30258509299405	3.40612221436757	2.95000031891613	0.456121895451437	1.22640155781204	1.18414106534539	0.383276603107641	0.371918881337024	0.385192194410042	0.636598261985598	NA	NA	0.0893195832272724	0.47516579729665	81.4274077672798
a7418	ARID1A_mut	193	GW-2580	CSF1R (cFMS)	8	24	2.99573227355399	NA	5.50023946818659	5.80188598446575	-0.301646516279166	0.608661413996139	0.589820363480119	0.507591660027471	0.495590010049625	0.511420993502768	0.636654089970532	NA	NA	0.193397856517238	0.245246427462648	81.4274077672798
a7419	gain_cnaOV49	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	0.0264841659324569	-0.368471734630625	0.394955900563081	0.320060088560768	1.45938727108484	0.279344934851855	1.23400547171971	0.270631317943106	0.636689816713782	NA	NA	0.889230976194205	0.242514801060888	81.4274077672798
a7420	loss_cnaOV33_(ZFHX3)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	4.25018590374904	4.00161904133654	0.248566862412501	1.36715668114228	1.52236658955273	0.164879715032017	0.18181300346996	0.163276614265116	0.637497352579959	NA	NA	0.33090418727381	0.753798579795342	81.5060578792349
a7421	PTEN_mut	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	3.70146649568434	4.0196137100025	-0.318147214318164	0.335409517624459	0.793361823416862	0.418567423490893	0.948533650957325	0.401011499328217	0.637516576268375	NA	NA	0.526584667779806	0.190682424566338	81.5060578792349
a7422	gain_cnaOV18_(CCNE1)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.24930074060248	3.52167473663562	-0.272373996033138	1.08781759790379	1.12730383177287	0.24309626148859	0.250385723266473	0.241615426432805	0.6375624956821	NA	NA	0.773995982636064	0.677713805238911	81.5060578792349
a7423	KRAS_mut	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	4.04641357196225	3.49858634653592	0.547827225426328	0.793298486872732	0.905438189725424	0.619609739934152	0.690568852067174	0.605040997434024	0.637779999440991	NA	NA	0.0606845906786622	0.22853464202554	81.5219380042258
a7424	loss_cnaOV56	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.09484038859554	4.83577665925331	0.259063729342227	0.627434671323853	0.62013943713381	0.417421611428089	0.412893550806838	0.417750773180271	0.637858551221923	NA	NA	0.0501813207616385	0.554889034733685	81.5219380042258
a7425	loss_cnaOV35	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.29630462302707	-0.0202311864727593	-0.27607343655431	1.29690889951057	0.905442291432637	0.285542149457053	0.21287033858623	0.304904508179635	0.638081869239741	NA	NA	0.549918312545383	0.668572355402812	81.5394960830539
a7426	gain_cnaOV4_(KRAS)	1036	PLX4720	BRAF	7	26	2.30258509299405	NA	4.52307756504271	4.24995563607238	0.273121928970336	0.944849559522339	1.3899198579562	0.207605520280835	0.289063932154882	0.196501925925389	0.638412247492799	NA	NA	0.372217162708384	0.553038619418589	81.5401026219073
a7427	loss_cnaOV40	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.78569013583769	1.56653377683032	0.219156359007375	0.691425893845476	0.680823840009052	0.320893152873294	0.316962903701077	0.321898773410257	0.638482711938627	NA	NA	0.210155196815029	0.474998977558261	81.5401026219073
a7428	gain_cnaOV96	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.73154298734025	3.39307680417222	0.33846618316803	0.579054058767892	1.20142878626584	0.302990497993929	0.584515690794426	0.281719721582513	0.638513098162496	NA	NA	0.774004834323039	0.442268149111393	81.5401026219073
a7429	loss_cnaOV58	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.30068053628264	2.08221065786489	0.218469878417747	0.561848317297787	0.557194649890143	0.39166535326532	0.388841385996276	0.392088973684189	0.638556932878059	NA	NA	0.0427867116222354	0.455827302128514	81.5401026219073
a7430	loss_cnaOV35	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	4.18932561105981	3.84969941841473	0.339626192645085	1.67128178013048	0.956972316626573	0.315601817561128	0.203213004941973	0.354896569884386	0.638601489039992	NA	NA	0.317551898191031	0.679233234947709	81.5401026219073
a7431	gain_cnaOV18_(CCNE1)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	3.16498957172963	2.77211786537772	0.392871706351907	1.40034086120053	1.58419063449477	0.250661200100729	0.28055434018764	0.247995220901683	0.638602241216959	NA	NA	0.968886011782155	0.631365970920423	81.5401026219073
a7432	loss_cnaOV35	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-4.62477355500483	-4.05643444980965	-0.568339105195182	0.774134428205439	2.52593248870237	0.241149411036463	0.734160740677402	0.225001700456037	0.638755272950918	NA	NA	0.928234206477712	0.363335478787132	81.5468151163505
a7433	loss_cnaOV33_(ZFHX3)	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.74118532313242	-4.10697109326998	0.365785770137564	1.51828660020155	1.53385344499114	0.238724536394305	0.240920106973878	0.238475045534534	0.639028149800711	NA	NA	0.864431383858441	0.676820520307579	81.5468151163505
a7434	PIK3R1_mut	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	9.09976807077179	8.69168947478957	0.408078595982218	1.68508558299162	1.72144940995814	0.237741606180857	0.242170842894362	0.237055235908526	0.639036313117874	NA	NA	0.92199402286463	0.639544564890326	81.5468151163505
a7435	loss_cnaOV85	1001	AICAR	AAPK1 (AMPK) agonist	7	24	7.60090245954208	NA	8.62015658765194	8.78733088749033	-0.167174299838392	1.33919993718156	1.21732927590351	0.134435902086776	0.124831472282042	0.137328743461224	0.639067757580846	NA	NA	0.530974932042023	0.773520878511831	81.5468151163505
a7436	loss_cnaOV82	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.39284420899018	3.97428002845346	0.418564180536722	0.130357766145885	1.08761964867726	0.398147437791065	3.21088795022999	0.384844261544715	0.639211230604941	NA	NA	0.105516470882447	0.062046949471798	81.5468151163505
a7437	gain_cnaOV26	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.98394226971704	4.77553226009603	0.208410009621002	0.116340219304911	0.689466885925488	0.312568774981715	1.79138401892462	0.302277040239936	0.639260634403934	NA	NA	0.762667050203743	0.163471576126255	81.5468151163505
a7438	loss_cnaOV35	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.90454465932759	3.64013834190831	0.264406317419283	1.15447613519744	1.04122038931808	0.250142559385734	0.229027096670184	0.253938858796694	0.639269269883756	NA	NA	0.831396862219085	0.652181873368883	81.5468151163505
a7439	loss_cnaOV38	1143	HG-5-88-01	EGFR, ADCK4	7	15	2.30258509299405	NA	3.60107133142894	3.63336909539462	-0.0322977639656741	1.00358664640681	0.876104256739427	0.0352513568231098	0.0321823373012299	0.0368652060724779	0.639342369166676	NA	NA	0.0606976195345081	0.943082451000636	81.5468151163505
a7440	SMARCA4_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.168865803531232	0.608224763378906	-0.439358959847674	1.16044821333952	1.21925569223574	0.361525615899825	0.378611432028744	0.360350140372956	0.639446674679936	NA	NA	0.432094740225527	0.587064118339263	81.5491566902185
a7441	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.65121211181295	5.72689958378314	-0.0756874719701948	0.512318130773096	0.476088119109887	0.157329402606076	0.147735298487253	0.15897786340836	0.639722796368698	NA	NA	0.382896927298769	0.770609636291275	81.5685440978465
a7442	gain_cnaOV51_(MYC)	295	NVP-BHG712	EPHB4	8	24	2.32630161961136	NA	2.96831234530998	3.34540222921602	-0.37708988390604	1.16759412484485	1.05568655631519	0.348243718070866	0.322963156358935	0.357198717413102	0.63977063116876	NA	NA	0.0629983346144745	0.435104278800131	81.5685440978465
a7443	RB1_mut	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.679155817769108	-0.746516079615624	0.067360261846516	0.778232672322356	0.940537077735796	0.0723587967581756	0.0865554277559479	0.0716189328853211	0.640010136853	NA	NA	0.0424055095476978	0.898674101445246	81.5819794504236
a7444	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.57387445278009	2.26583940532258	0.308035047457504	0.991953003062025	1.50991883353298	0.212207444757496	0.310533912903778	0.204007686119623	0.64006484769666	NA	NA	0.821383616304465	0.577441500482432	81.5819794504236
a7445	loss_cnaOV56	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-3.08764800579806	-3.75583075238934	0.668182746591278	3.01033509258872	1.5966265833798	0.385879559722857	0.221962913111004	0.418496568669702	0.64020866856606	NA	NA	0.246380531388361	0.739409916834585	81.5819794504236
a7446	gain_cnaOV26	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.19806266272609	2.46464404464215	-0.266581381916059	1.57871385155586	1.45985361248454	0.181585415957823	0.168859848574419	0.182608296911607	0.640227683044957	NA	NA	0.24127449749095	0.801856424227167	81.5819794504236
a7447	loss_cnaOV70	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.14871887436835	4.91655746649618	0.232161407872165	0.500315921416487	0.840336854201504	0.282210948777914	0.464029621953411	0.276271838741105	0.640377869841608	NA	NA	0.946108267025515	0.525116200084714	81.5819794504236
a7448	PIK3CA_mut	179	5-Fluorouracil	DNA antimetabolite	6	25	3.46573590279973	NA	3.15829676502813	4.08121389977125	-0.922917134743118	1.68492972297655	1.68856375168607	0.546772019878619	0.547748147686965	0.546569315977298	0.640633358646144	NA	NA	0.148300613626746	0.264565679304566	81.5819794504236
a7449	NF1_mut	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	5.54222510628225	5.75279567669792	-0.210570570415675	0.330354418338603	0.628285678914156	0.347975904225927	0.637408064570963	0.335150994973492	0.640650263316282	NA	NA	0.193437702110021	0.336504335888513	81.5819794504236
a7450	gain_cnaOV96	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	3.04173667348218	2.88006112685634	0.161675546625842	0.943938047477448	1.29797223421499	0.128666811628679	0.171277709440676	0.124560096405778	0.640755574459059	NA	NA	0.232748862203798	0.751135237143135	81.5819794504236
a7451	gain_cnaOV95_(MECOM)	1032	Afatinib	ERBB2, EGFR	8	23	-0.693147180559945	NA	0.60878338206003	0.269552333328309	0.339231048731721	1.49422313353516	1.7385260793471	0.201586448973144	0.227028374222221	0.19512566004136	0.64085318672121	NA	NA	0.837630526884962	0.604691628821912	81.5819794504236
a7452	loss_cnaOV35	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	3.83350531425893	3.5126168930377	0.320888421221229	1.75760602506091	0.712533767962204	0.34995181222379	0.182571302468145	0.450348370350148	0.640903366307435	NA	NA	0.143847543578917	0.706881265764893	81.5819794504236
a7453	gain_cnaOV51_(MYC)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.86080655273384	1.5004723555399	0.360334197193934	0.777655055594857	1.11705833298994	0.335147202609323	0.463359936518771	0.322574199173159	0.641031256095067	NA	NA	0.455737443876545	0.468519864395866	81.5819794504236
a7454	loss_cnaOV52, loss_cnaOV53	276	CAY10603	HDAC6	8	23	2.99573227355399	NA	1.11462153281288	1.54399676571928	-0.429375232906401	1.31484640895442	1.92275824760141	0.239210089470807	0.32655923154389	0.223312126442331	0.641142332351097	NA	NA	0.615562479972637	0.493161867521365	81.5819794504236
a7455	loss_cnaOV84	158	PF-562271	FAK	5	13	0.940007258491471	NA	2.50475387717078	2.20662673906792	0.298127138102863	1.80598681607238	1.24568560116655	0.211912730587442	0.165077139793979	0.239327754791157	0.641259393164064	NA	NA	0.748093342984216	0.746826338448814	81.5819794504236
a7456	loss_cnaOV85	158	PF-562271	FAK	5	13	0.940007258491471	NA	2.50475387717078	2.20662673906792	0.298127138102863	1.80598681607238	1.24568560116655	0.211912730587442	0.165077139793979	0.239327754791157	0.641259393164064	NA	NA	0.748093342984216	0.746826338448814	81.5819794504236
a7457	SMARCA4_mut	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	3.21056036125696	3.59630394975265	-0.38574358849569	0.734996407728433	0.928761152382184	0.42043085818211	0.52482377388464	0.415331312583751	0.641335235915915	NA	NA	0.143851229203307	0.467143568751053	81.5819794504236
a7458	loss_cnaOV87, loss_cnaOV88	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.59748061580128	3.27191987257074	0.325560743230537	0.697139322228663	1.13565136593974	0.292820189168508	0.466995237321806	0.286673140186064	0.641398395393767	NA	NA	0.951050226183998	0.522019252559024	81.5819794504236
a7459	gain_cnaOV95_(MECOM)	205	BMS-708163	g-secretase	9	23	2.32630161961136	0.940007258491471	5.14961502974199	5.02772223592912	0.121892793812872	0.566834471392933	0.638348140539038	0.196574398848228	0.215041250955211	0.190950338963849	0.641457432743878	NA	NA	0.11144291667111	0.604963344428072	81.5819794504236
a7460	loss_cnaOV82	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.277084168938545	0.358673546464603	-0.635757715403148	0.538843926343458	1.91311982223593	0.343811757387932	1.17985502725685	0.332314634981993	0.64152224879466	NA	NA	0.487237601237912	0.216547830102084	81.5819794504236
a7461	loss_cnaOV87, loss_cnaOV88	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.75575409061388	3.33572317300946	0.420030917604422	1.22716495311334	1.70545327730798	0.250344063152826	0.342277471776551	0.246286968510467	0.641555989027412	NA	NA	0.63063159185628	0.627509913815264	81.5819794504236
a7462	loss_cnaOV57_(ZNRF3)	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	2.88848410417625	3.30293628024855	-0.414452176072293	1.47229519094363	1.03503195290472	0.381384321302341	0.281500733427419	0.400424523039286	0.641708437072351	NA	NA	0.0630093360698463	0.619704203709306	81.5819794504236
a7463	ARID1A_mut	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	-0.824588886909901	-0.459225803329994	-0.365363083579907	1.67228227714765	1.44068804254738	0.243834729581901	0.218481705255583	0.253603190135377	0.641781626582687	NA	NA	0.90961141292242	0.678592088408187	81.5819794504236
a7464	gain_cnaOV72_(ASXL1)	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.59666705981834	3.37533388340272	0.221333176415614	1.24916851146821	1.2254423080019	0.180145989153484	0.177184402571491	0.18061492978523	0.642003801903363	NA	NA	0.327963272537956	0.728667342588521	81.5819794504236
a7465	loss_cnaOV38	1262	UNC1215	LMBL3	8	25	0	NA	2.90686072408283	2.73994933828567	0.166911385797167	0.709234468593473	0.409420977812906	0.338347422601217	0.235340205797075	0.407676682051794	0.642099099373602	NA	NA	0.110548898421358	0.543451156471562	81.5819794504236
a7466	BRCA1_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-1.80331384904981	-2.16774991859738	0.364436069547564	0.798726174007608	1.34051921244894	0.280765410364184	0.456271600214384	0.271861877221282	0.642211776040733	NA	NA	0.608427559181922	0.469615878081608	81.5819794504236
a7467	loss_cnaOV55	1259	BMN-673	PARP1	8	25	2.30258509299405	NA	2.29638149243475	1.77369285117417	0.522688641260586	0.562111346516103	1.52896065340712	0.381088657094095	0.929866732810404	0.3418587915234	0.642227016059954	NA	NA	0.0346792598196944	0.162095132834921	81.5819794504236
a7468	gain_cnaOV26	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.4401980330808	5.16499948897991	0.275198544100885	0.425422745624098	0.792308073574092	0.35588305762078	0.646882534917513	0.34733780114024	0.642230986747258	NA	NA	0.334825580288968	0.395579813894877	81.5819794504236
a7469	loss_cnaOV44	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.77915298674642	-4.08138037259356	-0.697772614152855	0.727228534777448	2.43767489025106	0.296038994047964	0.95949564790715	0.286245149811996	0.642248072813218	NA	NA	0.928240361515899	0.296375928904038	81.5819794504236
a7470	loss_cnaOV16, loss_cnaOV17	294	MPS-1-IN-1	MPS1	6	25	2.99573227355399	NA	4.36505204676967	4.26436058893094	0.100691457838731	0.537796550288242	0.873008648136188	0.122051924464625	0.18722964620127	0.115338442584389	0.64242313270456	NA	NA	0.318130552120645	0.725719663547295	81.5819794504236
a7471	NF1_mut	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.250167567453283	-0.0366819600030971	-0.213485607450185	0.450631958992572	1.01097999357746	0.220172581166832	0.4737471526153	0.211166995199128	0.642455045054409	NA	NA	0.549958048800834	0.489553971663145	81.5819794504236
a7472	loss_cnaOV55	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	1.6094379124341	NA	1.0711209706902	1.41829098372782	-0.347170013037617	2.03369224845039	1.11203052999687	0.256183303814379	0.170709217828877	0.312194677819315	0.642460074757705	NA	NA	0.581844630151743	0.677791293343142	81.5819794504236
a7473	loss_cnaOV20	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	0.877756156523822	1.27647066106821	-0.398714504544392	1.4532601339542	1.20524529900591	0.321534180010733	0.274358661074341	0.330816062815804	0.642541442864411	NA	NA	0.268109720813467	0.587566933012592	81.5819794504236
a7474	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1164	XMD8-92	MAP2K5 (ERK5)	6	17	2.30258509299405	NA	3.04484712650126	2.87930709979415	0.165540026707105	0.765961346003599	0.886161813482001	0.192696899505027	0.216120601347327	0.186805642252455	0.642881006466463	NA	NA	0.331683566314163	0.671787460957651	81.614171838362
a7475	loss_cnaOV33_(ZFHX3)	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.57626903733	2.36742827182601	0.208840765503993	1.23271609606419	0.910529603155889	0.22036819023075	0.169415136356845	0.229361862349288	0.643104820089436	NA	NA	0.735459223235412	0.762804788015391	81.6316630418597
a7476	loss_cnaOV58	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	2.84680135886263	2.36425401809213	0.482547340770498	1.64976757581423	1.42749700491369	0.330717845166492	0.292494135443497	0.338037375286595	0.643315234712868	NA	NA	0.241306831319847	0.565881223898065	81.6474490092086
a7477	PTEN_mut	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.77438039660443	4.56187387817597	0.212506518428458	0.568379152719002	0.982747157048093	0.22381283660217	0.373881620062722	0.216237225317212	0.643457843959554	NA	NA	0.943287764428582	0.554439990469388	81.6495506247616
a7478	loss_cnaOV36	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.83831993002287	-2.15210144151515	0.31378151149228	0.530105285652215	1.33734132186443	0.241282914317846	0.591923000930314	0.234630835346378	0.643503899611322	NA	NA	0.608437674111804	0.457849502115326	81.6495506247616
a7479	gain_cnaOV48_(SOX17)	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.79337003855784	4.92354046155434	-0.130170422996505	0.3602831972004	0.892654658207243	0.150224717801189	0.361300288239921	0.14582394411959	0.643981158083024	NA	NA	0.155301554418244	0.646281366804869	81.6907198880289
a7480	gain_cnaOV94	281	CH5424802	ALK	7	25	1.63315443905142	NA	4.04429838929115	3.89493168997224	0.149366699318908	0.623756727539889	0.757691778284444	0.203811863674199	0.239463067449411	0.197133852576706	0.644059859235099	NA	NA	0.955903272756374	0.604216633542706	81.6907198880289
a7481	loss_cnaOV56	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.273367952934183	0.35826063357523	-0.631628586509413	0.542482554974702	1.91318275256805	0.341553561018574	1.16432976639934	0.33014545299532	0.644126885599015	NA	NA	0.487265046231405	0.220877746604492	81.6907198880289
a7482	SMARCA4_mut	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	3.05244436008038	3.70772805624965	-0.655283696169263	1.0793185031049	2.08596288804507	0.322100260624	0.607127269924673	0.314139671383792	0.644278497406175	NA	NA	0.748039775134037	0.424706538901697	81.6907198880289
a7483	PTEN_mut	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.0019030282282	4.50274417686163	-0.500841148633433	1.17564448018079	0.983581009545198	0.498957480499751	0.426014119979889	0.509201726927423	0.644295291180114	NA	NA	0.376116156252599	0.466167891913718	81.6907198880289
a7484	loss_cnaOV1	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.87372936772006	2.29092654389504	0.58280282382502	1.84076411871795	1.53458070548992	0.374514996766319	0.31660918305542	0.379779845882371	0.644510288874274	NA	NA	0.243318061042151	0.642970451849978	81.6907198880289
a7485	loss_cnaOV38	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.53868110034293	3.18123506224153	0.357446038101397	0.967842220907751	1.04385619595621	0.346286537237718	0.369322633772005	0.34242842978382	0.644585613439073	NA	NA	0.567117616498408	0.542853919742461	81.6907198880289
a7486	gain_cnaOV72_(ASXL1)	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	2.30254180522586	2.5427372867125	-0.240195481486646	0.486226869146121	0.824625306424878	0.309645914609872	0.493998782725565	0.291278329218396	0.644827610378817	NA	NA	0.750398266508278	0.477794143095399	81.6907198880289
a7487	loss_cnaOV39	231	FMK	RSK	5	15	2.99573227355399	2.32630161961136	5.22416409663777	5.24908584141975	-0.0249217447819721	0.748538086032146	0.753606868032082	0.0331193273224387	0.0332938901132972	0.0330699544273675	0.644844173340148	NA	NA	0.128043688074593	0.950496682438457	81.6907198880289
a7488	gain_cnaOV95_(MECOM)	1262	UNC1215	LMBL3	8	25	0	NA	2.85994496950362	2.75496237975102	0.104982589752602	0.489092193670394	0.498818532497397	0.211386154138174	0.214647853944998	0.210462488687004	0.64488597896936	NA	NA	0.110569726446078	0.608522085851677	81.6907198880289
a7489	loss_cnaOV54	1042	BIRB 0796	p38, JNK2	11	22	2.30258509299405	NA	4.48284821114928	4.35482374137925	0.128024469770032	0.970169419509936	0.810640677807096	0.147950269396673	0.13196094124952	0.157929984609651	0.645037388046745	NA	NA	0.86984784123079	0.710922859860007	81.6907198880289
a7490	loss_cnaOV54	136	Mitomycin C	DNA crosslinker	6	13	2.77258872223978	NA	-0.779098014118391	-0.452116738189159	-0.326981275929232	0.402095137106089	1.76571894118108	0.218068593877975	0.81319380851642	0.185183082257993	0.645334723721002	NA	NA	0.909624715572338	0.536606221052111	81.6907198880289
a7491	gain_cnaOV96	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	4.21405051266555	3.85800033518101	0.35605017748454	0.981283093503589	1.08651143323954	0.330662698123752	0.362841446919555	0.327700350490506	0.645376417517329	NA	NA	0.317622835706036	0.538143779938281	81.6907198880289
a7492	gain_cnaOV19	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.94020486300097	2.38787071357923	0.552334149421732	0.398181300762646	1.50836006675601	0.378094431338387	1.3871423604369	0.366181896216347	0.645412614817198	NA	NA	0.241328588953342	0.156524201405043	81.6907198880289
a7493	loss_cnaOV87, loss_cnaOV88	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.74318368900123	4.46230786206406	0.280875826937168	0.61579225162222	0.681142227429503	0.414982396120443	0.456121080116288	0.412360026476611	0.645464797179846	NA	NA	0.0540267073474263	0.519902241504111	81.6907198880289
a7494	loss_cnaOV40	208	SB-715992	KIF11	7	25	-2.05572501506252	NA	-1.36935527962204	-1.30285131216412	-0.0665039674579242	1.92190759878231	1.87827754821232	0.0352416523671319	0.0346031034478764	0.0354068904892252	0.64547434130416	NA	NA	0.0748498855912526	0.936879876529782	81.6907198880289
a7495	loss_cnaOV52, loss_cnaOV53	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	1.84897985522571	2.24293878167313	-0.393958926447425	0.832128899946406	1.71438569123414	0.25374557656523	0.473434976808038	0.229795972085969	0.645476456159282	NA	NA	0.947962316389683	0.514757367194195	81.6907198880289
a7496	PIK3R1_mut	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	2.61769826703398	2.12617696481789	0.491521302216094	1.04353416531985	1.34477497034464	0.374946350324221	0.471016013227932	0.36550449930677	0.645486724182913	NA	NA	0.687385291736182	0.523925610479497	81.6907198880289
a7497	loss_cnaOV34	1005	Cisplatin	DNA crosslinker	5	26	1.79175946922805	2.30258509299405	3.40021840633337	2.95113566661502	0.449082739718348	1.22417324834793	1.18496101022867	0.377238945268743	0.366845738807314	0.378985245794445	0.645620377026735	NA	NA	0.0893845306784936	0.481040573132835	81.6907198880289
a7498	loss_cnaOV54	333	T0901317	LXR	10	22	2.32630161961136	NA	5.07248452962538	4.60829139767459	0.464193131950791	0.611427917271188	1.26077699816753	0.419428823143785	0.759195186936332	0.368180203656532	0.645806445299746	NA	NA	0.00521488891343793	0.171286109761147	81.6907198880289
a7499	loss_cnaOV70	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.67710901819771	3.04662373837434	-0.369514720176636	1.16475175742859	1.07922355924572	0.340524135122308	0.317247617631769	0.342389412287195	0.645810794778459	NA	NA	0.435730969334538	0.643678415664704	81.6907198880289
a7500	loss_cnaOV40	1021	Axitinib	PDGFR, KIT, VEGFR	7	23	0.693147180559945	NA	2.79009118099276	2.44468471870617	0.345406462286586	0.655636154735437	1.11835840368936	0.333166616031378	0.526826441452066	0.308851313807026	0.645837883461631	NA	NA	0.19691199739865	0.323841799307787	81.6907198880289
a7501	gain_cnaOV50	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	4.2419555500081	4.00279480615668	0.239160743851419	2.34237335987768	1.3842830859427	0.158621759202053	0.102101888600675	0.172768667247386	0.645925813252767	NA	NA	0.330995587508476	0.853672070132483	81.6907198880289
a7502	loss_cnaOV34	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	0.985936101548731	1.3923365184483	-0.406400416899572	0.688507651793033	1.41303204172399	0.299671793834677	0.590262745579096	0.287608776658552	0.645943978794331	NA	NA	0.581875257673155	0.382832455749833	81.6907198880289
a7503	loss_cnaOV55	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	2.50067194361958	2.06754582247698	0.433126121142598	1.36782252262269	1.36885917019821	0.316443884136638	0.316653742703486	0.316413938389208	0.645997962926562	NA	NA	0.892789158009647	0.652559541284554	81.6907198880289
a7504	loss_cnaOV70	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	0.138890847667865	-0.084290954927705	0.22318180259557	0.305019884272467	1.00077475556275	0.230074236417506	0.731695912638295	0.223009025112821	0.64612365077563	NA	NA	0.549990894962218	0.408135598056483	81.6907198880289
a7505	loss_cnaOV84	290	KIN001-260	IKK	6	25	2.99573227355399	NA	4.72438583972474	4.88045296074954	-0.156067121024802	1.39113165937651	0.769108273546538	0.172011646398596	0.112187167888012	0.202919571135466	0.646176033011052	NA	NA	0.666217477607093	0.800066292109404	81.6907198880289
a7506	loss_cnaOV36	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.1346729786612	5.92847738528881	0.206195593372386	1.2454903822376	0.652135231613885	0.292212065938144	0.165553741974259	0.316185329938546	0.646359488618113	NA	NA	0.908930612892773	0.802601838767935	81.6907198880289
a7507	loss_cnaOV41	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.54502952195976	8.77988590094417	-0.234856378984411	0.654516229277241	1.29374741519086	0.188949309881973	0.358824378188077	0.18153186335044	0.646732297082937	NA	NA	0.531048474478501	0.585283055890092	81.6907198880289
a7508	loss_cnaOV42	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.54502952195976	8.77988590094417	-0.234856378984411	0.654516229277241	1.29374741519086	0.188949309881973	0.358824378188077	0.18153186335044	0.646732297082937	NA	NA	0.531048474478501	0.585283055890092	81.6907198880289
a7509	loss_cnaOV55	1018	ABT-888	PARP1, PARP2	7	24	1.6094379124341	NA	4.4967077720927	4.24209067683693	0.254617095255769	0.759953444629651	0.810826491254485	0.318046227104944	0.335043017509911	0.314021677883062	0.646902136519003	NA	NA	0.226349925896027	0.459621098003337	81.6907198880289
a7510	loss_cnaOV55	1129	PF-4708671	RPS6KB1 (p70S6KA)	8	24	2.30258509299405	NA	4.45343180984605	4.11156414030502	0.341867669541029	0.862293637388755	1.00031233323561	0.352489465627532	0.396463170685442	0.34176092624513	0.647050360557521	NA	NA	0.0486963489123812	0.367458668102156	81.6907198880289
a7511	loss_cnaOV54	294	MPS-1-IN-1	MPS1	9	22	2.99573227355399	NA	4.32965061580553	4.26511233916554	0.0645382766399907	0.530250701864583	0.913150294909562	0.0781848240278389	0.121712760422659	0.0706765107559676	0.647126383850527	NA	NA	0.318182780470084	0.808111257019031	81.6907198880289
a7512	loss_cnaOV21, loss_cnaOV22	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	3.03203086771022	2.61741781866871	0.414613049041509	0.434719613073832	1.76686710067077	0.242111967174805	0.953748201305774	0.234660008601726	0.647218713743967	NA	NA	0.640898004461042	0.330672305832096	81.6907198880289
a7513	PIK3R1_mut	309	Y-39983	ROCK	5	27	2.99573227355399	NA	5.01986100366634	4.95399859482376	0.0658624088425812	0.691159219573299	1.312053777099	0.0528058513646754	0.0952926720463089	0.0501979491939768	0.647313924973662	NA	NA	0.373850913396966	0.872091298428381	81.6907198880289
a7514	loss_cnaOV38	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	1.73186411977405	1.24966947874072	0.482194641033328	1.8810751216734	1.40465560270706	0.326450506125932	0.256339917251347	0.343283179239123	0.647377087459256	NA	NA	0.857306265869469	0.708129769920373	81.6907198880289
a7515	gain_cnaOV51_(MYC)	1005	Cisplatin	DNA crosslinker	8	23	1.79175946922805	2.30258509299405	3.02662148511211	3.02250641229393	0.00411507281817247	1.11012167944042	1.23060884983098	0.00342172392014192	0.00370686645832081	0.00334393241096687	0.647545060499265	NA	NA	0.0893981139216918	0.993126757413503	81.6907198880289
a7516	loss_cnaOV87, loss_cnaOV88	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	4.09148550855138	3.77093625855617	0.32054924999521	1.37201630290714	1.00683347643241	0.309651181314464	0.233633703415916	0.318373651153354	0.647614031174753	NA	NA	0.717913670896926	0.728228259582941	81.6907198880289
a7517	gain_cnaOV26	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-1.18925104653217	-1.64408740853347	0.454836362001305	0.136309781659197	1.40267120238268	0.344988704970891	3.33678446597832	0.32426441865256	0.647618325678452	NA	NA	0.623657352690214	0.22352063218764	81.6907198880289
a7518	loss_cnaOV52, loss_cnaOV53	273	CUDC-101	HDAC, EGFR	8	23	1.63315443905142	NA	-0.191646582986791	0.22580294477003	-0.417449527756821	1.26335193511965	1.72551292760486	0.256729523731616	0.330430117018251	0.241927789168333	0.647672279468194	NA	NA	0.463105924920353	0.476747102902228	81.6907198880289
a7519	loss_cnaOV44	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.34122623588327	2.52836359491779	-0.187137359034516	0.401160200988085	0.645439822428883	0.296057331100194	0.466490341199312	0.289937733203835	0.647790159458426	NA	NA	0.858480883531913	0.521875956880794	81.6907198880289
a7520	gain_cnaOV95_(MECOM)	1058	GDC0941	PI3K (class 1)	8	25	1.38629436111989	0.693147180559945	1.05678525359494	0.775738559003205	0.281046694591735	1.79474921219005	1.19055937096288	0.20805622001057	0.156593853159454	0.236062729374373	0.648154855498795	NA	NA	0.164370916368503	0.688025703227784	81.6907198880289
a7521	PTEN_mut	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	1.1697242999851	1.30232409900231	-0.132599799017214	1.50732075060825	2.39482289600831	0.056518658467334	0.0879705258245169	0.0553693549691005	0.648281604530563	NA	NA	0.364749243754243	0.900246723338476	81.6907198880289
a7522	gain_cnaOV95_(MECOM)	255	CP724714	ERBB2	9	23	2.32630161961136	NA	4.53938044400809	4.36642615897743	0.172954285030657	0.493881641702434	1.07455791828986	0.181125656655929	0.350193792250457	0.160953897492943	0.648320444675788	NA	NA	0.787015206285977	0.538775329243502	81.6907198880289
a7523	loss_cnaOV83	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	1.94939122716464	1.51524028332899	0.434150943835653	0.911807561101676	1.07015967946996	0.410837936658093	0.476143171384867	0.405688003542317	0.648323425389016	NA	NA	0.288741253901069	0.508266232360187	81.6907198880289
a7524	PIK3CA_mut	1375	Temozolomide	DNA akylating agent	7	26	3.40119738166216	NA	5.84230628588882	5.97546909590101	-0.133162810012193	0.594637109290633	0.730266285682793	0.188602055654874	0.2239396228921	0.182348292154398	0.648338887649116	NA	NA	0.908934484172746	0.626805974390786	81.6907198880289
a7525	KRAS_mut	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	-0.241827275326762	0.186309860326934	-0.428137135653697	0.369643001699611	1.41838986379949	0.319895833916623	1.15824493818395	0.301847289367135	0.648417714915963	NA	NA	0.870505478142701	0.318413729771233	81.6907198880289
a7526	loss_cnaOV20	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	2.98435584695004	2.76456451749329	0.219791329456751	1.55472075518471	0.845357390336463	0.227386688683728	0.141370293490832	0.259998116736486	0.648450748906209	NA	NA	0.966281706555744	0.771962838562566	81.6907198880289
a7527	MLL2_mut	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-5.75994917042886	-4.52949917994643	-1.23044999048243	0.79738029692424	1.41661025638313	0.88980191139468	1.54311561901979	0.868587520765235	0.648502437379303	NA	NA	0.136488302042609	0.0903268539061106	81.6907198880289
a7528	gain_cnaOV94	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	2.15193913765349	1.57574313661504	0.576196001038445	1.29035606728958	2.44883972697888	0.245977356364814	0.446540312123891	0.235293471716622	0.648526232171403	NA	NA	0.615056854955285	0.574795675532509	81.6907198880289
a7529	gain_cnaOV72_(ASXL1)	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-2.87481653203618	-2.71325140923596	-0.16156512280022	0.750199312676989	1.32326083073271	0.13013656333048	0.215362930983895	0.122096202840644	0.648620336897824	NA	NA	0.381157235413263	0.757625669341658	81.6907198880289
a7530	gain_cnaOV26	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.685610346097558	0.240675447148243	0.444934898949315	2.15998447063669	1.03371892199309	0.390138205620707	0.205989860111431	0.430421548336803	0.648753598237103	NA	NA	0.14782934566015	0.756645387891982	81.6907198880289
a7531	loss_cnaOV81_(RB1)	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.29256424069528	4.46265297514203	-0.170088734446749	0.676734092737248	1.04609223120363	0.167371937073018	0.251337617348013	0.162594395955934	0.648772343471005	NA	NA	0.376161793722487	0.68024848916303	81.6907198880289
a7532	gain_cnaOV26	173	FH535	unknown 	3	15	3.46573590279973	NA	2.64276922022857	2.46763782138879	0.175131398839774	1.27194849585818	1.48369138704346	0.120043032822656	0.137687492386721	0.118037619122907	0.648782520566193	NA	NA	0.122952410865884	0.845290787307517	81.6907198880289
a7533	loss_cnaOV41	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	1.03057450168582	1.51061636021605	-0.48004185853023	1.52903909910576	1.83533987588359	0.267254188816849	0.313950021821534	0.261554747890563	0.648792438831338	NA	NA	0.615625272678479	0.555785666922126	81.6907198880289
a7534	PIK3R1_mut	1527	GDC0941 (rescreen)	PI3K	5	26	1.38629436111989	NA	0.562983861330967	0.34753075761421	0.215453103716757	1.29341677841371	0.839106842194776	0.235396671082651	0.166576703899725	0.256764803815943	0.648924511610606	NA	NA	0.909905523607557	0.73577219514195	81.6907198880289
a7535	gain_cnaOV51_(MYC)	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.4659550051382	1.60112764056508	-0.135172635426883	0.551110696479506	1.35416826303994	0.106359559220558	0.245273111718509	0.0998196746417888	0.648956321865644	NA	NA	0.165473183365643	0.750314702685295	81.6907198880289
a7536	loss_cnaOV42	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	-0.315479038304784	0.182304119223537	-0.497783157528321	1.47549677788869	1.6445118715355	0.305793375190843	0.337366482250544	0.302693562840344	0.648960708652108	NA	NA	0.463119085786359	0.567345851579959	81.6907198880289
a7537	loss_cnaOV41	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.41606613246676	4.54831389857296	-0.132247766106201	1.64100353435117	0.858937539347994	0.132910844064471	0.0805895681135689	0.15396668564118	0.649009390073601	NA	NA	0.326755143722546	0.868139024269033	81.6907198880289
a7538	loss_cnaOV57_(ZNRF3)	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.34615143917906	3.96600170340731	0.380149735771753	0.569952521028737	1.09123827637985	0.361767664912773	0.66698491847286	0.348365470676935	0.649069907345726	NA	NA	0.105590661774446	0.316882292594575	81.6907198880289
a7539	loss_cnaOV58	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.89855879762518	3.64124683481616	0.257311962809013	0.934340342743745	1.07493372116677	0.243374238433575	0.275394255216896	0.239374723987372	0.649095652973338	NA	NA	0.831433698912753	0.600519560694448	81.6907198880289
a7540	loss_cnaOV21, loss_cnaOV22	308	XL-880	MET	3	29	1.63315443905142	NA	-0.0518725294804386	0.284647117624518	-0.336519647104957	0.856597296853943	0.981746475321939	0.345536897476264	0.392856302886905	0.342776526897745	0.649166339120878	NA	NA	0.369571581694557	0.57533413030389	81.6907198880289
a7541	loss_cnaOV59	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.97613433848302	1.49372146512407	0.482412873358953	1.32036684956698	1.24678106199445	0.38361114855802	0.365362757719314	0.386926693117431	0.64926893622055	NA	NA	0.165477266554493	0.537554954135415	81.6927960598864
a7542	loss_cnaOV54	1072	BMS-708163	g-secretase	11	22	1.6094379124341	NA	3.93033953949376	3.79689443702343	0.13344510247033	0.980158631510326	0.81116097333064	0.15351335104255	0.136146434036605	0.164511246050709	0.649505076927706	NA	NA	0.923944467740942	0.701562578962136	81.7007340470359
a7543	loss_cnaOV1	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.31643778247248	0.79661442188074	0.51982336059174	0.241007020898969	1.39199460102591	0.38570176959868	2.15688056992187	0.373437770669961	0.649512680702901	NA	NA	0.164382816894422	0.0870241584933078	81.7007340470359
a7544	gain_cnaOV95_(MECOM)	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.14964718894142	-4.83425777208586	0.684610583144436	1.17500989539687	2.26755894654325	0.331817958108936	0.582642398014192	0.301915230996787	0.649590345530685	NA	NA	0.35206010378775	0.407687348903824	81.7007340470359
a7545	gain_cnaOV4_(KRAS)	294	MPS-1-IN-1	MPS1	8	23	2.99573227355399	NA	4.16709974725259	4.32445778373351	-0.157358036480924	1.02898942498775	0.745530200480084	0.191214501085552	0.152924833491653	0.211068627910168	0.649873294746787	NA	NA	0.318212869376717	0.69944072377394	81.7254881578361
a7546	KRAS_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	7	26	-2.30258509299405	NA	-0.53608986356876	-0.277771942159233	-0.258317921409527	1.15420281330239	1.47015249531757	0.182618868647182	0.223806352256612	0.175708249472262	0.650073636821205	NA	NA	0.889263207759794	0.630343433247775	81.7287372980545
a7547	PTEN_mut	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.02015222078625	4.55449707283534	-0.534344852049095	0.811009383794888	0.66729245574962	0.782894854418824	0.658863957342615	0.800765612506177	0.650139118356422	NA	NA	0.0822245872771131	0.283419645920507	81.7287372980545
a7548	loss_cnaOV20	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-4.60932609094893	-4.05952394262083	-0.549802148328098	1.18888109276359	2.49964817669821	0.233219334501894	0.462453437668915	0.219951813000473	0.65015754079767	NA	NA	0.928254010268146	0.465122356378563	81.7287372980545
a7549	gain_cnaOV19	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	3.37759197119762	3.03688302458685	0.340708946610762	1.23484294364477	0.894913557204177	0.370078408922585	0.275912777705254	0.380717158509901	0.650425409538776	NA	NA	0.240089324405127	0.683177995073	81.7310766442054
a7550	loss_cnaOV38	207	AS601245	JNK 	4	14	2.07944154167984	NA	2.13510648456459	1.95300314327023	0.18210334129436	1.34689654866491	0.900755902580055	0.182159782644714	0.135202173823125	0.202167247278377	0.650510532186925	NA	NA	0.481674613178365	0.812189491489501	81.7310766442054
a7551	SMAD4_mut	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.64095534975077	4.50325821120817	0.1376971385426	0.404694552109088	0.614380201934603	0.228476547293465	0.340249548270377	0.224123658459386	0.650599680884812	NA	NA	0.616017782914658	0.63248519605611	81.7310766442054
a7552	loss_cnaOV84	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-1.87996724546686	-2.27682790571427	0.396860660247412	3.19979432039299	2.51132365130699	0.147574594610607	0.124026928142891	0.158028480335806	0.650605376239279	NA	NA	0.419113956890609	0.810310600868656	81.7310766442054
a7553	loss_cnaOV81_(RB1)	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.66837038215369	4.4944240230598	0.173946359093884	0.390350800527847	0.620186567469446	0.289346274398719	0.445615479355153	0.280474244715811	0.650709701702124	NA	NA	0.61601863560789	0.476460470855472	81.7310766442054
a7554	loss_cnaOV42	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.72469140689021	4.40304922808067	0.321642178809541	1.18214365650315	0.992115444650561	0.317807557446514	0.272083834346307	0.324198338554067	0.650745020873869	NA	NA	0.37618166472924	0.633627898304616	81.7310766442054
a7555	gain_cnaOV50	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	4.64311206318283	4.3506663642671	0.292445698915722	0.649571153533179	1.01925727286335	0.295839038995667	0.450213494434039	0.2869203945871	0.650779122504503	NA	NA	0.51263132965181	0.471148108266596	81.7310766442054
a7556	loss_cnaOV36	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.71881414450985	-2.35619863754021	0.63738449303036	1.27502259428397	1.63873922411321	0.393996085045351	0.499900547557203	0.388948091100508	0.650909474000215	NA	NA	0.12529467345632	0.486801604139787	81.7366285551025
a7557	gain_cnaOV26	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	4.20665269101019	3.58832719442932	0.618325496580864	1.94167865405751	2.04199088798394	0.303777201769702	0.318448933498215	0.302805218289362	0.65104629068398	NA	NA	0.748076453041608	0.644311682543781	81.7429907420195
a7558	loss_cnaOV21, loss_cnaOV22	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	3.11396768824013	2.88373899061419	0.230228697625938	1.3779878600391	1.24693296310569	0.183289176998395	0.167075998492037	0.184635986406612	0.651259247865889	NA	NA	0.232856298775366	0.803688260260829	81.7589099029245
a7559	loss_cnaOV102	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	9.12316598407083	8.70955498075425	0.413611003316579	1.35476614948164	1.23019630669178	0.333775446734111	0.305300662756325	0.336215448759436	0.651477220788436	NA	NA	0.531092972838581	0.655572825035882	81.7706425535043
a7560	gain_cnaOV96	155	AP-24534	ABL	4	15	-0.669430653942629	NA	0.992323645890128	0.734211426018927	0.258112219871201	1.54837189966785	1.20264228784729	0.203156685704522	0.166699111451564	0.21462094130518	0.651525066664279	NA	NA	0.586045896507637	0.772364031076849	81.7706425535043
a7561	loss_cnaOV1	1028	VX-702	p38	3	28	0.693147180559945	NA	3.60810174974025	3.29684787933742	0.311253870402826	0.414756186540045	0.955838509526631	0.335150376614486	0.750450217510558	0.325634369509732	0.651632480059644	NA	NA	0.519273297377518	0.348755212505661	81.773307059743
a7562	PIK3R1_mut	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.26977304207033	-2.83679488377957	0.567021841709243	1.70415644244676	1.1449760975447	0.463218035141072	0.332728749301404	0.495225920370887	0.651732428175252	NA	NA	0.381215974140131	0.628183926781147	81.775034167806
a7563	SMARCA4_mut	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	1.88400312228621	1.66287772878806	0.22112539349815	1.52645916343802	1.49259916847351	0.147921799675926	0.144861650278355	0.148147873969604	0.652069659003447	NA	NA	0.327756599260991	0.829668483757125	81.7759598451944
a7564	gain_cnaOV72_(ASXL1)	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	3.98131391844635	3.76759401598339	0.213719902462963	0.710487070844485	1.0780383216976	0.206176133645168	0.30080758853069	0.198248891678002	0.652270208401937	NA	NA	0.71794141699214	0.588891181848274	81.7759598451944
a7565	loss_cnaOV44	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.6576329757738	2.27841852690651	0.37921444886729	0.548658967819069	1.49546205529991	0.261224137097055	0.691166045047391	0.25357677750723	0.652408940151856	NA	NA	0.821432174770001	0.402688511946906	81.7759598451944
a7566	gain_cnaOV50	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-3.47639178386722	-3.2913060085082	-0.185085775359023	2.05516835114931	1.81030533720267	0.10074613816775	0.0900586928830028	0.102240087103219	0.652414899452661	NA	NA	0.140557230349024	0.873416687641325	81.7759598451944
a7567	loss_cnaOV38	1133	JNJ-26854165	MDM2	8	25	2.30258509299405	NA	3.2732665898684	3.00212535729005	0.271141232578343	1.19235534050884	0.821430693195016	0.295239378646942	0.227399688135445	0.330084126177121	0.652494051772313	NA	NA	0.2401095163076	0.563409289455751	81.7759598451944
a7568	loss_cnaOV85	197	Bryostatin 1	PRKC	6	13	-4.8283137373023	NA	-2.1824990886598	-2.39251230179395	0.210013213134154	0.955303424207122	0.660292743216533	0.276676285361657	0.219839275995959	0.318060762126661	0.652530629428374	NA	NA	0.675815945665665	0.64025030665402	81.7759598451944
a7569	loss_cnaOV34	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	3.49452684552342	3.57314876245475	-0.0786219169313296	1.63382370018183	0.764921440425287	0.0850753266323997	0.04812142027477	0.102784302774435	0.652769400987402	NA	NA	0.143946730832811	0.920657859114421	81.7759598451944
a7570	gain_cnaOV96	207	AS601245	JNK 	4	14	2.07944154167984	NA	2.13357596769534	1.9534404338043	0.180135533891044	0.977667877793933	1.0047885617562	0.180178871346248	0.184250232602008	0.179277054643414	0.652996200846478	NA	NA	0.481720849356209	0.75983635921707	81.7759598451944
a7571	loss_cnaOV34	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.89723672816151	1.70931554893159	0.187921179229917	1.52778501332891	1.73915177587253	0.10968090858069	0.12300237113889	0.108053352120827	0.652998920626871	NA	NA	0.23049743821882	0.812486846935989	81.7759598451944
a7572	loss_cnaOV35	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.61552318221363	4.34494409411637	0.27057908809726	1.00251315866316	0.986175034785262	0.273763212751751	0.269900784602244	0.274372275258599	0.653008780590398	NA	NA	0.512651819656601	0.600091385576405	81.7759598451944
a7573	gain_cnaOV94	228	KIN001-102	AKT1	7	25	2.32630161961136	NA	3.10426715398263	2.7005462873308	0.40372086665183	0.559192408593035	1.34285135820674	0.329073481328874	0.721971293686942	0.300644493662324	0.653290522646312	NA	NA	0.0956663887767322	0.248675725415547	81.7759598451944
a7574	loss_cnaOV41	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.898693435866693	0.516374705249493	0.3823187306172	1.63085860777656	1.15801218391576	0.314539377261822	0.23442788283065	0.330150870541284	0.653295299184323	NA	NA	0.432241186868428	0.677933471256142	81.7759598451944
a7575	loss_cnaOV42	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.898693435866693	0.516374705249493	0.3823187306172	1.63085860777656	1.15801218391576	0.314539377261822	0.23442788283065	0.330150870541284	0.653295299184323	NA	NA	0.432241186868428	0.677933471256142	81.7759598451944
a7576	gain_cnaOV51_(MYC)	157	JNK-9L	JNK	5	14	1.63315443905142	NA	0.0327205842623722	-0.0544353052687976	0.0871558895311698	1.08757940469659	0.998237449687645	0.0854500186281858	0.0801374953909545	0.0873097774066095	0.653518500323949	NA	NA	0.192653578714641	0.879865846918277	81.7759598451944
a7577	PIK3CA_mut	263	FR-180204	ERK	6	26	2.99573227355399	NA	4.7509970776764	4.82578865756905	-0.0747915798926453	0.675399370522669	0.76735600250069	0.0993498302815005	0.110736822029856	0.0974665991390066	0.65354004848518	NA	NA	0.765847578704351	0.817597472927258	81.7759598451944
a7578	loss_cnaOV40	1043	JNK Inhibitor VIII	JNK	8	25	2.30258509299405	NA	4.64707151300293	4.37642484551507	0.270646667487862	0.928671945890498	1.0335072500837	0.267758723273355	0.291434094338168	0.26187205504939	0.653700837443439	NA	NA	0.376211168754098	0.497682579339434	81.7759598451944
a7579	gain_cnaOV4_(KRAS)	261	TL-1-85	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	3.41975145853628	3.60088108323215	-0.181129624695862	0.828878473986333	1.00200578436032	0.187817167167411	0.21852374066943	0.180767044984172	0.653723885006426	NA	NA	0.729201657158313	0.61991979330882	81.7759598451944
a7580	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.49868472400172	-2.08606496211727	-0.412619761884451	1.20797347595818	1.30402279454057	0.317878944478611	0.341580150637957	0.316420666580315	0.65375464798267	NA	NA	0.60851623219816	0.621870680892174	81.7759598451944
a7581	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	8.42577881299551	8.8213027935927	-0.395523980597185	1.99918908163347	1.66730964019513	0.230370411804176	0.197842207238355	0.237222871542262	0.653764001790844	NA	NA	0.922020611783636	0.694612943928113	81.7759598451944
a7582	loss_cnaOV20	164	JQ12	HDAC	4	15	1.63315443905142	NA	1.25756253984763	1.93691452883025	-0.679351988982627	2.78068454738732	2.08661168909741	0.305342571061252	0.24431105988665	0.325576623830996	0.653930069627713	NA	NA	0.661991888017671	0.672592580002959	81.7759598451944
a7583	loss_cnaOV84	1033	Vismodegib	SMO	6	25	2.30258509299405	NA	5.1460664772509	4.85451376702759	0.291552710223307	1.04030000006243	0.816434565631824	0.339329044779144	0.280258300688082	0.357104809737789	0.653961405003804	NA	NA	0.1553930271652	0.543408947488192	81.7759598451944
a7584	ARID1A_mut	1161	ZG-10	IRAK1	6	17	2.30258509299405	NA	1.32045706568279	1.66838251748192	-0.34792545179913	0.940078582538866	1.34684484624468	0.275705773246145	0.370102519365444	0.258326304450901	0.65401003337218	NA	NA	0.165538622089517	0.502322800755219	81.7759598451944
a7585	loss_cnaOV70	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	1.96263020849329	2.33445132579943	-0.371821117306144	1.30609560612535	1.25891794320568	0.294575197214018	0.284681393584338	0.295349763908636	0.654058188240699	NA	NA	0.844964745186289	0.677288531486145	81.7759598451944
a7586	gain_cnaOV94	333	T0901317	LXR	7	25	2.32630161961136	NA	5.10290860104833	4.65547583351026	0.447432767538066	0.795820490140707	1.17848626257792	0.402174783583158	0.562228257604874	0.379667359515345	0.6540955157286	NA	NA	0.00522212035377197	0.26081473783947	81.7759598451944
a7587	loss_cnaOV1	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.21349846122451	2.46304723790094	-0.249548776676429	0.743633144488707	1.50683474948509	0.169952024309248	0.335580492243939	0.165611243543264	0.654139783122849	NA	NA	0.24141734485568	0.651721534496301	81.7759598451944
a7588	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.11348312851044	-2.3660753168593	0.252592188348868	1.4401698262864	0.614630610915068	0.33243364756786	0.175390557237405	0.410965844953291	0.65423226699307	NA	NA	0.675836710505745	0.791698506843649	81.7759598451944
a7589	gain_cnaOV19	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	1.36831068453769	1.58566590441162	-0.217355219873933	1.58474632153893	1.63677120425644	0.133072905358781	0.137154582357927	0.13279511474096	0.654343038274045	NA	NA	0.0796269797285839	0.838997277719324	81.7759598451944
a7590	PTEN_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.18457150866838	4.47959228634568	-0.2950207776773	0.308645458102364	0.567451034840971	0.532555578265208	0.955856533548777	0.519905259772731	0.654689200686636	NA	NA	0.366193992499173	0.234513597183034	81.7759598451944
a7591	loss_cnaOV36	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	4.19995488635109	3.58902007077337	0.61093481557772	1.47973777076697	2.06966210416941	0.300116414452865	0.41286694686523	0.295185776628451	0.655299471262258	NA	NA	0.748099035921978	0.56254145000838	81.7759598451944
a7592	gain_cnaOV19	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.43451260364036	1.84699451359704	0.587518090043326	1.64816958627442	1.359494576233	0.425755539774888	0.356467013428741	0.43215920115788	0.655459410256062	NA	NA	0.0347270228596991	0.604203356801754	81.7759598451944
a7593	loss_cnaOV16, loss_cnaOV17	328	SNX-2112	HSP90	6	26	0.940007258491471	NA	1.09205456793002	0.604786259688739	0.487268308241283	1.76202390995882	2.41783600060687	0.209899547711633	0.276538987630804	0.201530752341755	0.655526554348364	NA	NA	0.945993000275633	0.584263471292921	81.7759598451944
a7594	PTEN_mut	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.67964876466476	2.49335436780246	0.186294396862302	0.0920289065324402	0.653844892298222	0.294713216716678	2.02430305739462	0.284921391994804	0.655569817635776	NA	NA	0.858504810154736	0.171548160979826	81.7759598451944
a7595	gain_cnaOV26	1262	UNC1215	LMBL3	3	30	0	NA	2.95795275961715	2.76265869903176	0.195294060585388	0.142835088915733	0.510852271080102	0.394192127096238	1.36726949986781	0.382290677053222	0.655569837843197	NA	NA	0.110647641137856	0.149961877052669	81.7759598451944
a7596	loss_cnaOV35	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	2.98561131910494	2.32908498866678	0.656526330438167	1.78615140750413	1.53944980947216	0.415808716085521	0.367564769526208	0.426468161805986	0.655588613261492	NA	NA	0.229426950655805	0.532759934932049	81.7759598451944
a7597	gain_cnaOV96	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	2.99452908336319	2.83605317730297	0.158475906060219	1.27212657871251	1.05639296094623	0.146749526819671	0.124575579751355	0.150016056447659	0.655928218765689	NA	NA	0.308171509303924	0.824951630150943	81.7759598451944
a7598	loss_cnaOV56	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.808987492122432	1.25676656053873	-0.447779068416295	1.94624005247166	1.17767150165673	0.360618851017507	0.230073915007365	0.380224084378681	0.655960474225742	NA	NA	0.268244508382528	0.730933176255379	81.7759598451944
a7599	gain_cnaOV95_(MECOM)	274	PXD101, Belinostat	HDAC	8	22	2.99573227355399	NA	0.560800072415297	0.961656931879968	-0.400856859464671	1.15101271738492	2.3156588809944	0.192131797486563	0.348264492138202	0.173107042127264	0.65597033510526	NA	NA	0.417379081683838	0.536681046388214	81.7759598451944
a7600	loss_cnaOV39	328	SNX-2112	HSP90	9	23	0.940007258491471	NA	0.415100999035732	0.806124398615903	-0.391023399580171	2.64730468329088	2.19270011663424	0.168352670529887	0.147706231945349	0.178329629580348	0.655970482416323	NA	NA	0.945993518461109	0.700597434304088	81.7759598451944
a7601	gain_cnaOV18_(CCNE1)	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.80792162975987	4.4897045966668	0.318217033093069	1.0250587795549	0.986651441998225	0.321290700590828	0.310437839702465	0.322522239919497	0.656010263324261	NA	NA	0.326825682073272	0.591656791530205	81.7759598451944
a7602	loss_cnaOV52, loss_cnaOV53	263	FR-180204	ERK	8	24	2.99573227355399	NA	4.69393375102301	4.85104239811123	-0.157108647088224	0.742044259831127	0.752574293476608	0.20944175127009	0.211724091934864	0.208761644464949	0.656070100723568	NA	NA	0.765860052983152	0.614563773536569	81.7759598451944
a7603	gain_cnaOV94	1019	Bosutinib	SRC, ABL, TEC	7	24	0.693147180559945	NA	1.75781228437973	1.71348645053325	0.0443258338464778	1.98412557183055	1.50038083341536	0.027490297343538	0.0223402361603469	0.0295430552425664	0.656120818971211	NA	NA	0.0417854303344045	0.957686081421564	81.7759598451944
a7604	gain_cnaOV50	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.38536187410577	2.54082596943978	-0.155464095334011	1.2897349464769	1.02550735187436	0.148542696730007	0.12053956959039	0.151597250911818	0.656200266997997	NA	NA	0.197018584113074	0.856599919635269	81.7759598451944
a7605	loss_cnaOV39	163	JQ1	BRD4	5	14	0.940007258491471	NA	0.330821661600361	0.00197162412733603	0.328850037473025	2.16928349827834	1.78614853727602	0.174611575016023	0.151593850104893	0.184111248650429	0.656272952317235	NA	NA	0.583869826306241	0.77118601431211	81.7759598451944
a7606	loss_cnaOV38	304	SB52334	ALK5	8	24	2.99573227355399	NA	4.1555146921184	4.43701573778475	-0.281501045666352	1.31466015821209	0.974684763776664	0.264624452299173	0.214124573493721	0.288812399791297	0.656324057080165	NA	NA	0.353179320431316	0.590294688727483	81.7759598451944
a7607	loss_cnaOV52, loss_cnaOV53	225	Genentech Cpd 10	AURKA, AURKB	8	24	2.32630161961136	NA	3.21361234932243	2.72099922729672	0.492613122025705	1.77304696431367	1.87955441682604	0.265523897944374	0.27783422094315	0.262090375046214	0.656332166800349	NA	NA	0.347690239509991	0.51470814394326	81.7759598451944
a7608	gain_cnaOV48_(SOX17)	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.43178517961276	5.16586978416626	0.265915395446499	0.581801091818381	0.785486638914615	0.343747392455283	0.457055511215006	0.338535860793178	0.656442228406019	NA	NA	0.334975408382378	0.52336498602583	81.7759598451944
a7609	loss_cnaOV41	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-4.60050025324782	-4.06128911016105	-0.539211143086768	0.688546998198862	2.53116579352386	0.228691449362799	0.783114507066715	0.213028772933947	0.656707234756985	NA	NA	0.928265013001635	0.371598579720481	81.7759598451944
a7610	loss_cnaOV40	256	JW-7-24-1	LCK	7	25	2.32630161961136	NA	2.15949616243999	1.87770165849407	0.281794503945918	1.14424761870635	1.39385546398486	0.209102591380093	0.246270561842641	0.202169099470544	0.656713078914544	NA	NA	0.839505289308989	0.594375207013963	81.7759598451944
a7611	loss_cnaOV87, loss_cnaOV88	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.347704737701653	-0.0339534805791342	-0.313751257122519	1.73629617638429	0.887770410787011	0.324200795357699	0.180701461760909	0.35341486189473	0.656906974094659	NA	NA	0.550084901013982	0.785297635667529	81.7759598451944
a7612	gain_cnaOV50	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-4.76828519740028	-4.63084013926612	-0.13744505813416	1.22339106516055	1.45445489442543	0.095962326931519	0.112347606622518	0.0944993610052492	0.656963963022273	NA	NA	0.136560640386225	0.847280094590052	81.7759598451944
a7613	loss_cnaOV43_(NF1)	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.07704516840819	4.32361927545579	-0.246574107047597	0.508905801781243	0.860133465796423	0.300453085620076	0.484518168558017	0.286669588910004	0.657110297875629	NA	NA	0.318290693465828	0.40631349782594	81.7759598451944
a7614	loss_cnaOV52, loss_cnaOV53	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	1.16436874117766	1.84613313520806	-0.681764394030399	0.937299223644768	2.614963874712	0.29241699446557	0.727371128484775	0.260716563094198	0.657432757079613	NA	NA	0.615182415814456	0.41449081897977	81.7759598451944
a7615	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	203	BMS-345541	IKBKB	7	25	2.77258872223978	NA	3.41091889792167	3.23846706205983	0.172451835861843	0.85333939602492	1.09038688372698	0.164666627919934	0.202090559354425	0.15815655748939	0.65752777977017	NA	NA	0.0928261641343415	0.665622848185637	81.7759598451944
a7616	SMARCA4_mut	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	3.54188233871019	3.93708549182603	-0.39520315311584	0.810305376162562	1.09307254173918	0.36692360300761	0.487721252680614	0.361552539310002	0.65771489692181	NA	NA	0.317747572916099	0.497705764265739	81.7759598451944
a7617	NF1_mut	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-1.03920083650542	-0.782284596216747	-0.256916240288677	0.761814396950832	0.813764709624623	0.317751184156505	0.3372425636966	0.31571317513534	0.657915279252585	NA	NA	0.0796106681562436	0.565883100523704	81.7759598451944
a7618	loss_cnaOV57_(ZNRF3)	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.25866471711703	0.786658177081776	0.472006540035254	0.918981969457233	1.38523099797201	0.350366074125291	0.513618934563024	0.340742115016395	0.658029970774459	NA	NA	0.164456124197206	0.410222777536789	81.7759598451944
a7619	TP53_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	12	7	1.63315443905142	NA	1.32148433543255	0.929736186750808	0.391748148681745	1.91900532652528	0.638508607346688	0.246448852129651	0.204141251338306	0.613536206363212	0.65804997310354	NA	NA	0.536621374377981	0.526841412812713	81.7759598451944
a7620	gain_cnaOV18_(CCNE1)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	2.13528981574263	2.46932681907163	-0.334037003329001	1.58395777255906	0.805115247161037	0.338020133309173	0.210887568542517	0.414893401294868	0.658074369728499	NA	NA	0.412540395940283	0.707498579150965	81.7759598451944
a7621	NF1_mut	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	3.76197789816325	3.51328621191964	0.248691686243611	1.3673588052424	0.841184414432786	0.274000028839282	0.181877416000933	0.295644667181934	0.658119295718841	NA	NA	0.664188624789926	0.744365776267399	81.7759598451944
a7622	loss_cnaOV55	151	QS11	ARFGAP	4	15	2.32630161961136	NA	3.71008517936658	3.78189795550845	-0.071812776141869	1.08639158152515	1.54923468814299	0.0485836806985926	0.0661021102916258	0.0463537104426369	0.658312484601183	NA	NA	0.0659091135152483	0.91833312567466	81.7759598451944
a7623	gain_cnaOV94	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	NA	0.932035109854018	1.2925274432135	-0.360492333359481	1.09566518873131	1.27158667931744	0.290839819982305	0.32901687218602	0.283498041638014	0.658358435859379	NA	NA	0.268267898125437	0.471753208948772	81.7759598451944
a7624	KRAS_mut	1053	MK-2206	AKT1, AKT2	7	25	1.38629436111989	0.693147180559945	1.3561009688126	1.2969529502979	0.0591480185146942	1.36195002046204	1.19171424067793	0.048179817927781	0.0434289200235324	0.0496327194017976	0.658404997057804	NA	NA	0.098441223112394	0.919308016662572	81.7759598451944
a7625	loss_cnaOV83	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.37445004836166	4.26642602931089	0.108024019050768	0.368462487849229	0.876233961372273	0.130939590407191	0.293175079181927	0.123282164139804	0.658465696702127	NA	NA	0.318305037530752	0.656671655058045	81.7759598451944
a7626	loss_cnaOV52, loss_cnaOV53	1043	JNK Inhibitor VIII	JNK	9	24	2.30258509299405	NA	4.38452501784421	4.46360283672093	-0.0790778188767183	0.870911250671047	1.06337097037991	0.077740982049685	0.0907989405531137	0.0743652225605387	0.658507440570596	NA	NA	0.376258459694055	0.829824032825744	81.7759598451944
a7627	loss_cnaOV34	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	4.01692110519381	3.76100009251164	0.255921012682172	1.32679920794454	0.982741498974126	0.247208466862473	0.192886015570239	0.260415391992019	0.658510761776699	NA	NA	0.71797785754923	0.698655777453267	81.7759598451944
a7628	loss_cnaOV55	299	OSI-027	MTORC1/2	7	25	2.99573227355399	NA	1.2084960915688	1.6213684610096	-0.412872369440808	1.28905885047498	2.05533723663752	0.214298841336732	0.320289775202023	0.200878163486327	0.658561194685893	NA	NA	0.783216649716594	0.526605799419988	81.7759598451944
a7629	loss_cnaOV52, loss_cnaOV53	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	9	24	0.693147180559945	NA	2.68050822988466	2.84187548565001	-0.161367255765347	0.975080313819638	0.964407096004123	0.166844295022525	0.165491245673118	0.167322758650313	0.658573102529168	NA	NA	0.966288899488717	0.677416591662397	81.7759598451944
a7630	loss_cnaOV39	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	2.86963471694976	2.13262224259105	0.737012474358706	2.53654036345713	1.38272040532605	0.431538117979911	0.290558149586947	0.533016271055113	0.658610680964625	NA	NA	0.64699260448242	0.672200628514485	81.7759598451944
a7631	loss_cnaOV85	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	2.86963471694976	2.13262224259105	0.737012474358706	2.53654036345713	1.38272040532605	0.431538117979911	0.290558149586947	0.533016271055113	0.658610680964625	NA	NA	0.64699260448242	0.672200628514485	81.7759598451944
a7632	loss_cnaOV84	1011	ABT-263	BCL2, BCL2L1, BCL2L2	6	27	0.693147180559945	NA	1.85887229081254	1.7108809357784	0.147991355034136	1.40215624235436	1.76737658917424	0.0863556464165057	0.105545552317082	0.0837350431937547	0.658738872804694	NA	NA	0.230552045444692	0.829107995162723	81.7759598451944
a7633	SMARCA4_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.56892680092068	1.1277685903958	0.44115821052488	1.15629092309931	1.52000408823798	0.294261657713975	0.381528732701978	0.290234884194475	0.658876523464573	NA	NA	0.813594176436157	0.588498073118381	81.7759598451944
a7634	RB1_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.52550063096965	3.98170947860381	0.543791152365838	1.50364676184382	1.5008680434137	0.362273010251432	0.361648204993986	0.362317763211878	0.658885890296431	NA	NA	0.331130713923778	0.601769286795892	81.7759598451944
a7635	SMAD4_mut	164	JQ12	HDAC	3	16	1.63315443905142	NA	2.25204549337085	1.70798947573324	0.544056017637612	2.60863043944554	2.17947452288325	0.243507653470162	0.208560020388802	0.249627151831935	0.659017979550327	NA	NA	0.662055497147732	0.76007816679625	81.7759598451944
a7636	loss_cnaOV102	262	VX-11e	ERK	3	29	1.63315443905142	NA	3.06856716345814	2.83762694148793	0.230940221970214	1.67610617300879	1.07761318453885	0.204835823200432	0.137783766738149	0.214307160754573	0.659085075218163	NA	NA	0.392144250792842	0.83539696050978	81.7759598451944
a7637	gain_cnaOV94	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	2.84252546419565	2.94470422969611	-0.102178765500452	0.709404502262844	0.893297378769888	0.118632842225452	0.1440345602185	0.114383818791853	0.659096468779303	NA	NA	0.331930056483126	0.795272215370357	81.7759598451944
a7638	gain_cnaOV4_(KRAS)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	5	26	2.30258509299405	NA	1.65997477953521	1.36076538772201	0.299209391813194	0.967185591971682	1.54079381791411	0.202854135847158	0.309360886159639	0.1941917136053	0.659146518514733	NA	NA	0.477770281934076	0.585269894062029	81.7759598451944
a7639	loss_cnaOV52, loss_cnaOV53	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-2.80530178784047	-1.94635128343798	-0.858950504402494	0.516959074703115	3.03486805973761	0.322218923696943	1.66154449439887	0.283027297231748	0.659286820893199	NA	NA	0.419271773358314	0.324749507898294	81.7759598451944
a7640	loss_cnaOV36	1028	VX-702	p38	3	28	0.693147180559945	NA	3.14805682189127	3.34613840732124	-0.198081585429973	1.94902894486309	0.806702172305915	0.212626429173305	0.101630910075523	0.245544876696894	0.659538615567383	NA	NA	0.519346889580917	0.877072486019461	81.7759598451944
a7641	loss_cnaOV56	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.80321918592376	2.20571811453339	-0.402498928609627	2.24704713930799	1.2090016211078	0.307879548014893	0.179123491255988	0.332918435825437	0.659555100898308	NA	NA	0.687429826459641	0.787293538238954	81.7759598451944
a7642	RB1_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.8915584191608	2.19625319668656	-0.30469477752576	1.36224206532503	1.30582663599541	0.232627771219785	0.223671537740292	0.233334785129035	0.659563168015398	NA	NA	0.687429879132269	0.741648615047027	81.7759598451944
a7643	loss_cnaOV85	152	CP466722	ATM	7	25	2.77258872223978	NA	2.80019074115948	2.60399994929228	0.1961907918672	0.576942754534784	0.865883832767326	0.240335986164705	0.340052440775338	0.226578652288937	0.659568437509781	NA	NA	0.557071327194464	0.492245159927993	81.7759598451944
a7644	loss_cnaOV21, loss_cnaOV22	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	4.28334046629939	3.69413651999045	0.589203946308943	0.495764539134982	1.61116549533206	0.376872123632675	1.18847537449329	0.365700449777514	0.659571077395503	NA	NA	0.166341615750603	0.189741183727871	81.7759598451944
a7645	loss_cnaOV20	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	3.31856626744361	3.70698575460233	-0.388419487158722	3.95253387510529	1.54677647801002	0.190518063952504	0.0982710077717867	0.251115460236658	0.660048973688366	NA	NA	0.748123833170428	0.838504374404554	81.7759598451944
a7646	loss_cnaOV40	152	CP466722	ATM	7	25	2.77258872223978	NA	2.80000146014781	2.60405294797554	0.195948512172271	0.706978251542386	0.841449721689568	0.240036071503696	0.27716342298335	0.232870137242213	0.660071457758961	NA	NA	0.557075530992149	0.547281252473465	81.7759598451944
a7647	gain_cnaOV51_(MYC)	208	SB-715992	KIF11	8	24	-2.05572501506252	NA	-0.853676632770546	-1.47197319580387	0.618296563033321	0.637472428416812	2.10298396292932	0.33118322548415	0.969918910169785	0.29400916694204	0.660154208337078	NA	NA	0.0749383575081195	0.212020477903441	81.7759598451944
a7648	NF1_mut	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	3.36695088575962	3.74020164119488	-0.373250755435259	1.16960680967149	1.23387252365592	0.303999567800734	0.31912498486572	0.302503498764466	0.660374023294692	NA	NA	0.199414903571382	0.584453814609548	81.7759598451944
a7649	loss_cnaOV87, loss_cnaOV88	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.22042489626106	2.46233071013853	-0.241905813877471	3.49398960044488	1.19934048661244	0.164733877770712	0.0692348408382984	0.201699030907178	0.660420038067332	NA	NA	0.241479465135892	0.915783260312712	81.7759598451944
a7650	loss_cnaOV33_(ZFHX3)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	1.93341019763384	1.71080614552954	0.222604052104301	1.7616599927281	1.70783200549879	0.129941096143472	0.126360394754482	0.130343061488233	0.660473963464683	NA	NA	0.230568324006692	0.824253961798949	81.7759598451944
a7651	gain_cnaOV50	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	1.43346498927596	1.58412083301594	-0.150655843739973	1.54209322532257	1.64373388312618	0.0922088565207736	0.0976956783585241	0.0916546439095385	0.660710397628005	NA	NA	0.0796660592834621	0.864909983919055	81.7759598451944
a7652	gain_cnaOV26	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	2.27473948915817	2.47744332247122	-0.202703833313048	1.19350254710818	0.803137465874468	0.236161412263035	0.169839464359915	0.25238996053103	0.660886656299874	NA	NA	0.62373371502523	0.800578412989811	81.7759598451944
a7653	loss_cnaOV16, loss_cnaOV17	230	GSK429286A	ROCK2	6	26	2.99573227355399	2.32630161961136	5.44950400989656	5.55934005774273	-0.109836047846175	1.83327350843283	0.705789700530342	0.111220202074032	0.0599125266038823	0.15562149428313	0.660902180998272	NA	NA	0.30559557537533	0.890540620395778	81.7759598451944
a7654	PTEN_mut	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	1.27317630574575	1.98691958606377	-0.713743280318016	1.83260182326179	1.31076379925534	0.520988389847815	0.389469917173632	0.544524712021723	0.661026392793066	NA	NA	0.03474644040157	0.499807329330709	81.7759598451944
a7655	loss_cnaOV33_(ZFHX3)	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.14883569870471	2.38664241055715	-0.237806711852432	1.27161139415604	0.814460120729749	0.273014752004488	0.187012095790682	0.29198079292005	0.661173844716488	NA	NA	0.651528309294124	0.73789829613026	81.7759598451944
a7656	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.180073005935254	-0.625742916460229	0.445669910524975	1.49113171561887	1.49914988835447	0.297468490489096	0.298880310744385	0.297281755471537	0.661178114545562	NA	NA	0.909681933587695	0.669394880936584	81.7759598451944
a7657	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.96689042095413	1.49566755302489	0.471222867929241	1.33610890053359	1.24476995841034	0.374514170782039	0.352682979464512	0.378562211230602	0.661236475734567	NA	NA	0.165630102268795	0.550569099196704	81.7759598451944
a7658	loss_cnaOV16, loss_cnaOV17	308	XL-880	MET	6	26	1.63315443905142	NA	0.0367668649463283	0.303021062807375	-0.266254197861047	0.509903567013248	1.04147842306105	0.27356997404485	0.522165787975609	0.255650229486741	0.661369537617157	NA	NA	0.369696500157617	0.374608173107856	81.7759598451944
a7659	gain_cnaOV4_(KRAS)	197	Bryostatin 1	PRKC	6	13	-4.8283137373023	NA	-2.45796406144477	-2.26537462204704	-0.192589439397727	0.816778329457638	0.735301802053239	0.253349638275782	0.235791563575898	0.261918900320854	0.661371677360126	NA	NA	0.675922399688535	0.634109224821542	81.7759598451944
a7660	gain_cnaOV4_(KRAS)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	7	26	0.693147180559945	NA	1.98072272311176	1.67238307496576	0.308339648146002	1.47829348091844	1.76085653533371	0.180335077944185	0.208578101795076	0.175107762590987	0.661410058114118	NA	NA	0.230577062677843	0.647875611378361	81.7759598451944
a7661	SMAD4_mut	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.46183910976646	1.28818478928821	0.173654320478245	1.85128480349675	1.13603690291306	0.141587840448688	0.0938020558210401	0.152859753088087	0.661447353049023	NA	NA	0.098462041061292	0.865560937162257	81.7759598451944
a7662	loss_cnaOV35	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.62568180699503	-4.04935536574973	0.423673558754703	2.49970540695612	1.72769081648583	0.230828401250827	0.169489395660671	0.245225334713805	0.661510181450688	NA	NA	0.592383591088392	0.801210717621125	81.7759598451944
a7663	loss_cnaOV20	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	2.4761701890804	2.1544825804086	0.321687608671793	1.17944640773864	1.33787921794796	0.243866021556218	0.272744574540327	0.240445926923956	0.661549370309958	NA	NA	0.687588084303801	0.700787072024666	81.7759598451944
a7664	loss_cnaOV39	295	NVP-BHG712	EPHB4	9	23	2.32630161961136	NA	2.98906723647759	3.35367596240722	-0.36460872592963	0.696476266092176	1.19256086811911	0.336749744774413	0.523504882622053	0.305735946631123	0.661632778249675	NA	NA	0.0631180790370908	0.294085566638502	81.7759598451944
a7665	loss_cnaOV55	305	TPCA-1	IKK	7	25	2.99573227355399	NA	3.14251564337972	3.37634523448895	-0.233829591109231	0.856851795749619	1.3145804945061	0.189081022927481	0.272893856637908	0.17787392410465	0.661688238521179	NA	NA	0.99363059732231	0.583438789930734	81.7759598451944
a7666	loss_cnaOV81_(RB1)	266	Zibotentan, ZD4054	Endothelin A Receptor	4	28	2.99573227355399	NA	5.84222541014154	5.69690884573727	0.145316564404274	0.433935757904014	0.484133223494269	0.303153308607371	0.334880363642255	0.300158215450368	0.661796106637093	NA	NA	0.383125497265703	0.569421103956853	81.7759598451944
a7667	loss_cnaOV33_(ZFHX3)	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.67980730281592	3.61413757065653	0.0656697321593871	1.02063308666041	0.903676436244533	0.0716883793927788	0.064342154901389	0.0726695192278058	0.66181792866571	NA	NA	0.0608771830223505	0.924062482838402	81.7759598451944
a7668	loss_cnaOV82	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.67980730281592	3.61413757065653	0.0656697321593871	1.02063308666041	0.903676436244533	0.0716883793927788	0.064342154901389	0.0726695192278058	0.66181792866571	NA	NA	0.0608771830223505	0.924062482838402	81.7759598451944
a7669	PIK3CA_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	7	24	2.30258509299405	NA	1.0202959803159	1.52240425484321	-0.502108274527306	0.940439140912364	1.57142307925177	0.343117854865654	0.533908312280778	0.319524564171721	0.661852470500238	NA	NA	0.477796300314081	0.309132247297915	81.7759598451944
a7670	loss_cnaOV102	308	XL-880	MET	3	29	1.63315443905142	NA	0.429391095988673	0.23486122533461	0.194529870654063	0.0363301555884376	1.01166435731149	0.19902675338316	5.35450144661572	0.192286966767346	0.661934660321783	NA	NA	0.369702148246812	0.312044757948284	81.7759598451944
a7671	loss_cnaOV40	283	GSK2126458	PI3K, MTOR	7	25	-2.05572501506252	0.0237165266173161	-2.42414479242777	-2.8184336546233	0.39428886219553	1.59069170364351	1.81856183992038	0.222093380336682	0.247872583538598	0.216813557581738	0.661964208274896	NA	NA	0.697128585795862	0.586134238551351	81.7759598451944
a7672	loss_cnaOV33_(ZFHX3)	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	4.41745592022123	4.55027707007155	-0.132821149850314	1.66513986291004	0.926430942783309	0.129637706743989	0.0797657619091486	0.143368645968662	0.662293861270329	NA	NA	0.192645029439215	0.885086936357012	81.7759598451944
a7673	loss_cnaOV38	1031	Elesclomol	HSP70	8	23	-1.6094379124341	NA	-3.87865873994559	-4.12276916918497	0.24411042923938	1.84811270421472	1.41886236661346	0.159183578056591	0.132086332550321	0.172046588156413	0.662486939414975	NA	NA	0.86450332087687	0.74062443483618	81.7759598451944
a7674	gain_cnaOV94	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	-0.184892038811121	0.175634503480251	-0.360526542291372	1.48962857440259	1.32028887402467	0.268784628550836	0.242024453938767	0.273066409468687	0.662517890544501	NA	NA	0.870577485754306	0.725091506847269	81.7759598451944
a7675	gain_cnaOV96	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	2.76282511794764	3.05558290973767	-0.292757791790026	1.62628795132008	1.63335036813799	0.179340794331905	0.180015963072462	0.179237595007719	0.662543240180762	NA	NA	0.664398464437016	0.725316448994273	81.7759598451944
a7676	loss_cnaOV40	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-1.25624296589003	-1.65654532083813	0.400302354948094	2.08431721046774	1.08670309552906	0.303539936870421	0.19205443055295	0.368364051409285	0.662600141716701	NA	NA	0.62386312967363	0.732357791416788	81.7759598451944
a7677	loss_cnaOV38	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.26704832365272	3.51694204782222	-0.249893724169498	1.4426215700957	1.03974726881734	0.222838932652105	0.173221951861513	0.240340832492631	0.662648602495331	NA	NA	0.774219426913222	0.762197366338052	81.7759598451944
a7678	loss_cnaOV41	1061	SB590885	BRAF	5	28	1.6094379124341	NA	4.10589582326892	3.89569053871823	0.210205284550685	1.51226009468975	1.25562883488611	0.162746595349039	0.139000748144327	0.16741036738755	0.662733346054129	NA	NA	0.574248636776688	0.781009321795246	81.7759598451944
a7679	loss_cnaOV34	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	1.41319895494816	1.12406583356768	0.289133121380474	1.69644222125712	1.46995135118094	0.192614486970315	0.170434994930872	0.196695707751272	0.662754891002693	NA	NA	0.813608726095436	0.734694561714958	81.7759598451944
a7680	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	257	NPK76-II-72-1	PLK3	7	25	2.32630161961136	NA	3.407625685723	3.1798800808174	0.227745604905595	0.816524601862875	1.32176503788219	0.184061704435701	0.278920689451365	0.172304152688515	0.662794929425961	NA	NA	0.602014052909059	0.582983084960209	81.7759598451944
a7681	loss_cnaOV34	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.5918005980995	2.90881036307506	-0.317009764975563	1.33437113886692	1.08720742185092	0.282210608885862	0.237572408261731	0.291581678531839	0.662827388039592	NA	NA	0.392181389548401	0.637311313566441	81.7759598451944
a7682	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.08352322841301	4.83694739996185	0.246575828451161	0.599789581607715	0.622582824737877	0.397005436354779	0.411103887116917	0.396053052949181	0.662874951158678	NA	NA	0.050300155908048	0.557201658550142	81.7759598451944
a7683	loss_cnaOV44	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.88240828318259	2.48559859065346	0.396809692529128	1.06687369254612	1.03837543552776	0.381387557276427	0.371936898717721	0.382144722373413	0.663081634273913	NA	NA	0.197087139443895	0.592301606665906	81.7759598451944
a7684	gain_cnaOV50	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	3.23250960926592	3.58486480137736	-0.352355192111441	2.2902303419805	1.64045767927045	0.204964605742243	0.153851420816798	0.214790784647453	0.663370331694437	NA	NA	0.699426060746247	0.783628834269267	81.7759598451944
a7685	loss_cnaOV20	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.603865804662132	0.223491622479618	0.380374182182514	1.12218939998753	1.14193786197659	0.333834657480831	0.338957204716727	0.333095341566241	0.663440192433255	NA	NA	0.147949379218645	0.514152101753261	81.7759598451944
a7686	gain_cnaOV26	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.2115519230236	2.78397310395625	0.427578819067344	1.86280100801825	1.36371491294781	0.304863913766899	0.229535423927125	0.313539739873554	0.663466636462025	NA	NA	0.628485818793819	0.732654313483258	81.7759598451944
a7687	SMARCA4_mut	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.65686519292522	4.82778937876131	-0.170924185836088	1.14963999184901	0.71479765816435	0.227397215819427	0.148676270004476	0.239122475967581	0.663491668760687	NA	NA	0.765895968759864	0.82263677106525	81.7759598451944
a7688	gain_cnaOV51_(MYC)	1019	Bosutinib	SRC, ABL, TEC	8	23	0.693147180559945	NA	1.78243624044153	1.70299438608364	0.0794418543578914	1.72832027934622	1.57336290941956	0.0492775522753808	0.0459647759198557	0.0504917548788529	0.663963874787368	NA	NA	0.0418183299274067	0.910813946875199	81.7759598451944
a7689	loss_cnaOV87, loss_cnaOV88	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-1.66726718154542	-2.02205633035625	0.354789148810829	2.18486525037785	2.03722947684734	0.173315109321304	0.162384910808331	0.174152766216535	0.663985857089011	NA	NA	0.279695557964674	0.809121382821714	81.7759598451944
a7690	loss_cnaOV21, loss_cnaOV22	333	T0901317	LXR	3	29	2.32630161961136	NA	4.715777372545	4.7572387561193	-0.0414613835742985	0.776382802143303	1.14979045565444	0.0367322427944602	0.0534032740805684	0.0360599475934068	0.664035532093339	NA	NA	0.00523051367613099	0.938708878956205	81.7759598451944
a7691	loss_cnaOV84	1007	Docetaxel	Microtubules	6	25	-4.38202663467388	NA	-4.26056968019435	-4.74169625874482	0.481126578550469	1.83095139904938	1.31775208408451	0.338932813871008	0.262774084992243	0.365111605104936	0.664108206444797	NA	NA	0.136619978974752	0.565050050599933	81.7759598451944
a7692	loss_cnaOV82	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.71172895482626	4.26750675429007	0.444222200536187	1.96689676252513	1.25655841900461	0.338061942951532	0.225849271298758	0.353522919283035	0.664123024605813	NA	NA	0.372475150227012	0.735787562766796	81.7759598451944
a7693	loss_cnaOV57_(ZNRF3)	305	TPCA-1	IKK	4	28	2.99573227355399	NA	3.57993342385228	3.28880380965974	0.291129614192539	1.68068245860597	1.1770707170106	0.235409330768648	0.173221070227635	0.247334004648352	0.664133464907517	NA	NA	0.993630925554986	0.757134115828233	81.7759598451944
a7694	loss_cnaOV84	1004	Vinblastine	Microtubules	6	25	-2.30258509299405	NA	-2.81944704251923	-3.43416588440299	0.61471884188376	2.06605736406302	1.76572016149405	0.337564753570588	0.297532320532902	0.348140580421091	0.664203420397633	NA	NA	0.140657252495769	0.52339951843955	81.7759598451944
a7695	gain_cnaOV18_(CCNE1)	151	QS11	ARFGAP	4	15	2.32630161961136	NA	4.24094367495593	3.64033569001795	0.600607984937981	1.3030418389102	1.48626852631842	0.412615640144005	0.460927628724721	0.404104624637193	0.66424522842916	NA	NA	0.0659653562662062	0.461051355085605	81.7759598451944
a7696	gain_cnaOV26	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.10066647093314	2.45494138351534	-0.354274912582198	1.86044359775458	0.804756453479778	0.358119044568276	0.190424968007513	0.440226246152247	0.664246147266657	NA	NA	0.412650475055597	0.774735039602497	81.7759598451944
a7697	loss_cnaOV87, loss_cnaOV88	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.42240978427317	4.26900348753829	0.153406296734882	0.541918795002663	0.841856908565489	0.1860189035394	0.283079860210659	0.182223718988402	0.664474556033234	NA	NA	0.318367759099105	0.690293681263044	81.7759598451944
a7698	PIK3R1_mut	290	KIN001-260	IKK	5	26	2.99573227355399	NA	4.94642366466844	4.83175079745173	0.114672867216711	0.915973737719536	0.90729438178777	0.126222689628069	0.125192309008998	0.126389923181002	0.664502941271199	NA	NA	0.666346171842122	0.806502127971906	81.7759598451944
a7699	loss_cnaOV38	1008	Methotrexate	Dihydrofolate reductase (DHFR)	8	23	-1.6094379124341	NA	0.80079101473773	0.483937507273966	0.316853507463764	1.39358131136103	1.15135778273852	0.260944216891941	0.227366358088076	0.27519986594447	0.664505749840842	NA	NA	0.432354342379667	0.575342936294883	81.7759598451944
a7700	loss_cnaOV38	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-2.87130877187603	-1.98601278798866	-0.885295983887367	4.39677046123989	2.1222112455884	0.3317681451706	0.201351421842866	0.41715733328984	0.664563425887449	NA	NA	0.419365216167733	0.719322449338994	81.7759598451944
a7701	loss_cnaOV16, loss_cnaOV17	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.50149303471999	2.07134769471203	0.430145340007963	0.96905439214938	1.61667416482038	0.276700783356871	0.443881523568447	0.266068048446704	0.664664481156403	NA	NA	0.94800207358814	0.563544023949645	81.7759598451944
a7702	MLL2_mut	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.37446379865219	2.39550608153419	-0.0210422828820018	0.30753631927806	0.980265795661961	0.0221416171460185	0.0684221067983076	0.0214658952450669	0.664693638937939	NA	NA	0.735578802682177	0.936134533667133	81.7759598451944
a7703	gain_cnaOV95_(MECOM)	271	VNLG/124	HDAC, RAR 	8	23	1.63315443905142	NA	4.40909072704451	4.30162045858372	0.107470268460789	0.586603282098889	0.591571217151006	0.182037021928209	0.183207751712974	0.181669197798979	0.664843438485697	NA	NA	0.255492830956559	0.663766927658289	81.7759598451944
a7704	SMARCA4_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.63412295043185	1.17425301470779	0.459869935724061	0.102444210904098	1.28311549792709	0.370472243033998	4.48897923724126	0.358401045320544	0.664890391888672	NA	NA	0.268330557447469	0.0663237577978387	81.7759598451944
a7705	loss_cnaOV35	1004	Vinblastine	Microtubules	5	26	-2.30258509299405	NA	-3.41646944483097	-3.29571085157828	-0.12075859325269	1.89276462839173	1.82873128634631	0.0657119484662962	0.0638001109283715	0.0660340828389054	0.664964598641645	NA	NA	0.140663561263961	0.900134458676502	81.7759598451944
a7706	loss_cnaOV41	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.65812337204409	5.72561972077738	-0.0674963487332931	0.521992243813036	0.474669159577233	0.140252780765698	0.129305271358531	0.14219661709939	0.665051702214141	NA	NA	0.383157646383338	0.797905093660083	81.7759598451944
a7707	loss_cnaOV35	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.35920263068478	3.59196831527548	-0.232765684590694	1.19371101460622	0.923416059346443	0.241497025803187	0.1949933289905	0.252070214974857	0.665133190702076	NA	NA	0.729264899675022	0.696487540764043	81.7759598451944
a7708	MLL2_mut	1218	JQ1	BRD2, BRD3, BRD4	3	28	0	NA	2.64186675513017	2.25671250547615	0.385154249654019	0.614619775494155	0.918258982959043	0.427658851408356	0.626654502524514	0.419439675300402	0.665293731931075	NA	NA	0.595560886473226	0.40021047867639	81.7759598451944
a7709	SMAD4_mut	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-1.86835569119946	-2.0532101353269	0.184854444127438	1.56243925495467	1.57373451970125	0.117549277230082	0.118311443815332	0.117462279573387	0.665356059493307	NA	NA	0.0384087759733572	0.836294923230351	81.7759598451944
a7710	gain_cnaOV49	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-2.64004752120307	-1.92477829639048	-0.715269224812586	2.09835780884431	2.03459622227485	0.350833692491316	0.340870952417084	0.351553402577763	0.665377120235041	NA	NA	0.279708825608782	0.620930020215361	81.7759598451944
a7711	gain_cnaOV50	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	-0.298078744670958	0.179726297944452	-0.47780504261541	0.921377621679292	1.69123607311599	0.29339101817575	0.518576782605777	0.282518242255255	0.665426734625843	NA	NA	0.463281838036171	0.426799606540908	81.7759598451944
a7712	loss_cnaOV57_(ZNRF3)	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.3885586312281	4.61699127322973	-0.228432642001636	1.67079854641043	0.831024935485171	0.240695697894715	0.136720637261987	0.274880610975014	0.665431602886382	NA	NA	0.943314823315134	0.804465268981725	81.7759598451944
a7713	loss_cnaOV57_(ZNRF3)	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	0.729158462303464	0.301975439771018	0.427183022532446	1.78114329992355	1.67163204421341	0.2537784419969	0.239836414369794	0.255548476718427	0.665492654965221	NA	NA	0.837719812325789	0.676266686417131	81.7759598451944
a7714	loss_cnaOV84	304	SB52334	ALK5	6	26	2.99573227355399	NA	4.46829494607762	4.34318175258906	0.125113193488557	0.93900439399778	1.09433192665881	0.116927017524024	0.133240264143911	0.114328377378653	0.665506404054619	NA	NA	0.35327178681799	0.782661720580745	81.7759598451944
a7715	loss_cnaOV56	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.96715398217889	5.75254459639456	0.214609385784333	0.712933787596856	0.55310721920468	0.379449014834756	0.301022885319735	0.388006842674956	0.665520616139589	NA	NA	0.111746525446667	0.658244350735816	81.7759598451944
a7716	ARID1A_mut	293	MP470	PDGFR	8	24	2.99573227355399	NA	4.40998253302031	3.9289961257161	0.48098640730421	0.971586714049946	1.94719105804959	0.271994777583991	0.495052474831891	0.247015517720172	0.665582732462678	NA	NA	0.623272365220904	0.368714931189532	81.7759598451944
a7717	SMARCA4_mut	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.39263262272767	4.32257494627138	0.0700576764562832	0.744396967962138	0.579104288648973	0.118343198358683	0.0941133286021748	0.120975924077035	0.665587214226277	NA	NA	0.255500309069473	0.887452779393036	81.7759598451944
a7718	gain_cnaOV51_(MYC)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	0.989432797685863	1.24420009600121	-0.25476729831535	1.9549626940466	1.47038440811348	0.159460729897445	0.130318240389541	0.173265777921448	0.665601061417525	NA	NA	0.536739550284526	0.799741991235474	81.7759598451944
a7719	PTEN_mut	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.60166681669811	2.76426206878395	-0.162595252085844	2.27438979126742	1.64374701410171	0.0960332759673771	0.0714896156807124	0.0989174433114943	0.665643174000607	NA	NA	0.322767770434052	0.914039166721836	81.7759598451944
a7720	gain_cnaOV72_(ASXL1)	272	AR-42	HDAC	3	27	1.63315443905142	NA	-0.00206147613736607	0.328115469486694	-0.330176945624061	2.1466943136105	1.83262934548665	0.177818013932406	0.153807155276217	0.180165698228729	0.665845475611983	NA	NA	0.487483865679102	0.818614831149338	81.7759598451944
a7721	TP53_mut	273	CUDC-101	HDAC, EGFR	21	10	1.63315443905142	NA	0.038367501194479	0.285457754073231	-0.247090252878752	1.6945376005297	1.48573562521501	0.151347946688121	0.145815739232646	0.166308358422107	0.665931104127726	NA	NA	0.463286666131363	0.683780118916687	81.7759598451944
a7722	loss_cnaOV38	1030	KU-55933	ATM	8	25	2.30258509299405	NA	4.33588617178533	4.09182948812122	0.244056683664108	1.13813423594919	0.999726636367771	0.236350971738303	0.214435763335569	0.2441234181284	0.665977522126127	NA	NA	0.530898917074162	0.598160792318955	81.7759598451944
a7723	loss_cnaOV41	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.30913782183722	3.95877645714573	0.350361364691484	0.696661254107438	1.09496663382577	0.333480445719796	0.502914957055229	0.319974466680628	0.666122567746919	NA	NA	0.105712830450349	0.378108285073836	81.7759598451944
a7724	loss_cnaOV21, loss_cnaOV22	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	3.82952718032715	4.11034926826703	-0.280822087939876	1.05110452802241	1.13154665979902	0.249317660600898	0.267168564546311	0.248175438023699	0.666174195892575	NA	NA	0.820177418658431	0.696788274135077	81.7759598451944
a7725	PIK3CA_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	7	26	-1.38629436111989	0.693147180559945	-2.62405438176372	-2.2105392648996	-0.41351511686412	1.63578493180357	1.61542625176175	0.255352929705256	0.252793083506516	0.255978950703041	0.666338827950433	NA	NA	0.125410641787336	0.565728187449057	81.7759598451944
a7726	loss_cnaOV56	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.02568500187584	3.35617880552601	-0.330493803650163	1.54722086672154	1.21146844929708	0.267240380385129	0.213604799908405	0.272804301128867	0.666421838102457	NA	NA	0.993631229989145	0.750541052505604	81.7759598451944
a7727	PIK3R1_mut	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.5970919584798	2.35583733214997	0.241254626329837	0.596603395169087	0.988916658961942	0.255011202639757	0.404380243698514	0.243958501602228	0.666495771507855	NA	NA	0.735588353193232	0.480900240319876	81.7759598451944
a7728	TP53_mut	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	12	7	0.940007258491471	NA	2.46185826972315	2.29125175890958	0.17060651081357	1.08341828805057	0.807635016086898	0.171489468189817	0.157470584256564	0.211242092548416	0.666698236715398	NA	NA	0.412693503541253	0.701490881497349	81.7759598451944
a7729	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.93092320154502	4.78969894648624	0.141224255058779	0.734376168308709	0.75415767306078	0.187910602365149	0.192305062654774	0.187260913869131	0.666760712747593	NA	NA	0.765911472295312	0.708420490595406	81.7759598451944
a7730	loss_cnaOV21, loss_cnaOV22	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.46196918497294	2.77871354792794	-0.316744362954997	0.727953296541903	1.73964586823853	0.18729691042476	0.435116324714335	0.182074046642444	0.666870178398099	NA	NA	0.322779917804408	0.576496423111893	81.7759598451944
a7731	gain_cnaOV95_(MECOM)	1192	GSK269962A	ROCK1, ROCK2	8	24	1.6094379124341	NA	2.659652794002	2.36631845544936	0.293334338552632	1.54315537619734	1.43958246794767	0.200309593369732	0.190087364550075	0.203763483568136	0.666897885383734	NA	NA	0.24154202943676	0.644925403184326	81.7759598451944
a7732	PIK3R1_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	0.645907045949634	1.27676526216234	-0.630858216212704	0.854401260495802	1.65665542245342	0.398392109314178	0.738362927796504	0.380802312697251	0.666904504799499	NA	NA	0.536759609456003	0.368799120233074	81.7759598451944
a7733	loss_cnaOV54	133	Doxorubicin	DNA intercalating	6	13	0.0237165266173161	NA	-1.71375077357697	-1.50697284882078	-0.206777924756188	0.444412913593314	1.55212352558056	0.155925806161593	0.465283339955806	0.133222595591317	0.666988489262091	NA	NA	0.623921236278792	0.664156315852653	81.7759598451944
a7734	loss_cnaOV56	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.71300599251584	-4.0969265297597	0.383920537243858	1.27489153336813	1.55041211153884	0.250437192227032	0.301139765380338	0.247624831092684	0.667120128906965	NA	NA	0.86451679608382	0.66477637210101	81.7759598451944
a7735	PTEN_mut	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	-1.17093681837463	-0.00767969791622504	-1.16325712045841	1.8118511230103	1.54103870379612	0.740352876021957	0.642026878304278	0.754852631275835	0.667235346790079	NA	NA	0.101616049057244	0.294857524187281	81.7759598451944
a7736	loss_cnaOV21, loss_cnaOV22	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.39556518788197	4.52864340036701	-0.13307821248504	0.289281037372904	0.619116696584247	0.220778063221744	0.460030887933703	0.214948511676798	0.667371602597035	NA	NA	0.616143802223299	0.545262431943218	81.7759598451944
a7737	loss_cnaOV21, loss_cnaOV22	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.85778073302357	5.70031059041859	0.157470142604985	0.483502848003635	0.479294044306985	0.328352992480078	0.325686070423728	0.32854600317989	0.667420020180739	NA	NA	0.383180786411914	0.636261324931995	81.7759598451944
a7738	loss_cnaOV35	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	4.75471279529892	4.39542785020794	0.359284945090977	1.11493933836641	0.961269512864395	0.365443553485711	0.322246182126281	0.373760886289193	0.66768003905836	NA	NA	0.0317867836268328	0.528393990443884	81.7759598451944
a7739	gain_cnaOV4_(KRAS)	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	8	23	2.32630161961136	NA	2.10256389568042	2.36035216521907	-0.257788269538653	1.49538757543338	1.39285036773573	0.181761245186763	0.172388933660855	0.185079657880065	0.667818427034948	NA	NA	0.531240545843268	0.676994195199786	81.7759598451944
a7740	gain_cnaOV19	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	0.886245204118757	1.23170185750563	-0.345456653386869	2.75177418934768	1.370815466146	0.216379403867689	0.125539608127788	0.252008138161811	0.667826106224221	NA	NA	0.536773732361665	0.849843092032497	81.7759598451944
a7741	gain_cnaOV50	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.779788674207962	-0.734958453273938	-0.0448302209340241	0.794610375630537	0.944458939022578	0.0481521331834662	0.0564178650429156	0.0474665642747995	0.667873751738102	NA	NA	0.0425187381193916	0.922456570759552	81.7759598451944
a7742	gain_cnaOV26	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.324211977752	2.09442217227914	0.229789805472856	0.353272021323497	0.570968580473753	0.410716157951698	0.650461377076996	0.402456130391958	0.66792374217315	NA	NA	0.042907086300358	0.386148172178183	81.7759598451944
a7743	loss_cnaOV34	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.302477161021	4.0435675746526	0.258909586368397	1.38897652375854	1.07909080285592	0.230070260657969	0.186403140686492	0.239933085967527	0.668025953843933	NA	NA	0.820184202123581	0.709128293559303	81.7759598451944
a7744	gain_cnaOV18_(CCNE1)	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.59702767094319	3.23035707689909	0.366670594044095	0.838370737647207	1.06261819583665	0.351767387666775	0.437360916332928	0.34506334964027	0.66805974055208	NA	NA	0.0928952469081971	0.469612661416537	81.7759598451944
a7745	loss_cnaOV43_(NF1)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.60953644101491	2.91084712279175	-0.301310681776836	0.695694867571236	0.817139859645753	0.375694220450141	0.433107524321334	0.368738200957986	0.66806522252512	NA	NA	0.0198345123297876	0.419380585521193	81.7759598451944
a7746	ARID1A_mut	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-2.29221311987847	-2.33832777542056	0.0461146555420937	0.369820040545836	0.851289699446562	0.0602223118232148	0.124694852864195	0.0541703436234147	0.668072160940698	NA	NA	0.676000741913839	0.871836145451942	81.7759598451944
a7747	gain_cnaOV51_(MYC)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	8	24	2.30258509299405	NA	0.724737691131351	0.917424303679416	-0.192686612548065	0.906408234860545	1.34161400664102	0.153700111650123	0.212582592630251	0.143622988127927	0.668074105502507	NA	NA	0.845369539106158	0.653055599876554	81.7759598451944
a7748	gain_cnaOV95_(MECOM)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	2.30258509299405	NA	2.33216086457306	2.10923816730964	0.222922697263422	1.13811553614243	1.35915760973677	0.17027086268715	0.195870006325548	0.164015339844653	0.668080043627359	NA	NA	0.687484602464008	0.657283064873206	81.7759598451944
a7749	PTEN_mut	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-1.347831728636	-0.736561501086291	-0.611270227549707	0.349998157821533	0.820865603324233	0.778333304903278	1.7464955568749	0.744665417912829	0.668142248700115	NA	NA	0.0796742680757066	0.0286362039350008	81.7759598451944
a7750	loss_cnaOV85	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	6	13	2.77258872223978	NA	5.18325874162599	4.96182653548398	0.221432206142013	1.37521940439105	1.11397048866624	0.185028998924732	0.161015911668338	0.198777443742817	0.668263941213076	NA	NA	0.801867222253629	0.738412064540916	81.7759598451944
a7751	loss_cnaOV87, loss_cnaOV88	152	CP466722	ATM	3	29	2.77258872223978	NA	2.8750296382161	2.62331879330259	0.251710844913512	1.03870162908428	0.798921866921322	0.308054195910946	0.242332194217717	0.315063156155044	0.668302303244786	NA	NA	0.557143195320512	0.719197465398961	81.7759598451944
a7752	loss_cnaOV59	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	3.15831823113358	2.87284371215652	0.285474518977058	0.931618177271669	0.841510190496203	0.333902230567143	0.306428669965518	0.339240715324821	0.668574513718906	NA	NA	0.332067378884799	0.600847805591577	81.7759598451944
a7753	loss_cnaOV44	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.23822903403121	4.33911818791743	-0.100889153886222	0.625873501317234	0.588950885294079	0.170544379469588	0.161197356452842	0.171303170443229	0.668605771230289	NA	NA	0.255530443773549	0.81085714758582	81.7759598451944
a7754	loss_cnaOV35	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.2783456691917	3.89238917899853	0.38595649019317	2.42833911656536	1.4117982856055	0.246456460162041	0.158938464385101	0.273379344718242	0.66869893917103	NA	NA	0.74447117120569	0.811918523432845	81.7759598451944
a7755	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.87806122529536	2.48608159708538	0.39197962820998	1.07368485818304	1.03802585401364	0.376681301037189	0.365078845270589	0.377620294036366	0.668700439294773	NA	NA	0.197141820987943	0.59860490022159	81.7759598451944
a7756	loss_cnaOV52, loss_cnaOV53	272	AR-42	HDAC	8	22	1.63315443905142	NA	-0.0371778809202452	0.415925286140482	-0.453103167060728	1.37539939104769	1.98069517630216	0.245178807807315	0.329433886629528	0.228759666041417	0.668759990412451	NA	NA	0.487511895205353	0.490674346941778	81.7759598451944
a7757	gain_cnaOV96	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	1.18897666578512	0.884879749691221	0.304096916093901	1.52220923502096	1.24353542161208	0.238263132023839	0.199773401118352	0.244542222769722	0.668794164023173	NA	NA	0.957615894648931	0.724712605558504	81.7759598451944
a7758	loss_cnaOV55	1009	ATRA	Retinoic acid and retinoid X receptor agonist	7	24	2.30258509299405	NA	4.33395278320832	4.5634974676917	-0.229544684483381	1.13770181962621	0.860115748827782	0.248314347727298	0.201761727478645	0.266876504466077	0.668830718075024	NA	NA	0.529752353012529	0.634270640138385	81.7759598451944
a7759	PIK3CA_mut	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	2.05997985217988	2.56271034185425	-0.502730489674375	1.12674725852225	1.68105837021272	0.317025402298051	0.446178578090098	0.299055939152643	0.66886300540523	NA	NA	0.229620565206476	0.456129158578457	81.7759598451944
a7760	loss_cnaOV1	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.18551850974049	1.79301544938902	-0.607496939648526	1.10157813759275	1.739187199394	0.356248710129054	0.551478754812684	0.349299339289181	0.668936134572269	NA	NA	0.230646214706799	0.453594892172929	81.7759598451944
a7761	loss_cnaOV84	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	6	27	-2.30258509299405	NA	-0.122868225367511	-0.379166303293196	0.256298077925686	1.58118538133041	1.3807971745457	0.181124448032151	0.162092364976228	0.18561602141894	0.66902775792304	NA	NA	0.88930619152925	0.724664307316493	81.7759598451944
a7762	gain_cnaOV4_(KRAS)	205	BMS-708163	g-secretase	8	24	2.32630161961136	0.940007258491471	5.14186148681018	5.0353856166486	0.106475870161582	0.574005482997353	0.634407194088902	0.171503107620712	0.185496259731849	0.167835218694985	0.669094526925325	NA	NA	0.111648287292531	0.665443180379992	81.7759598451944
a7763	loss_cnaOV34	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	4.83722789568266	4.8642927705822	-0.027064874899537	0.613215051919119	0.627284609078082	0.0432742379608938	0.0441360250614115	0.0431460847402492	0.669218813017274	NA	NA	0.0503285974439889	0.931134536063296	81.7759598451944
a7764	loss_cnaOV34	292	Masitinib	KIT	5	27	2.99573227355399	NA	3.94856070740285	4.0255499968558	-0.0769892894529525	0.683501490673205	1.10485396163677	0.0727405110501485	0.112639534080786	0.0696827744898503	0.669286171730864	NA	NA	0.105734655190586	0.841060454189204	81.7759598451944
a7765	loss_cnaOV44	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.92100805130593	5.706350179957	0.21465787134893	1.22158819710019	0.53555112254842	0.354248313189038	0.175720322002525	0.400816770446639	0.669331187757341	NA	NA	0.1937071522706	0.790599613466931	81.7759598451944
a7766	PIK3R1_mut	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	3.99013024465682	4.53701721143796	-0.546886966781136	0.965493676986252	0.971744596389657	0.563270555094341	0.566432468504839	0.562788791224563	0.669469694064154	NA	NA	0.0317926113476546	0.292171862521932	81.7759598451944
a7767	gain_cnaOV96	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.2167171099161	3.28720456619877	-0.0704874562826783	1.07191104035565	1.04604527838807	0.067160917058433	0.0657586811115323	0.0673847086153838	0.669488544328715	NA	NA	0.0929044112274621	0.896976494666837	81.7759598451944
a7768	NF1_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-2.35526033577219	-2.09161936870464	-0.263640967067556	1.42917273318392	1.28625410815016	0.202680475498902	0.184471030650168	0.204968027232749	0.669697108926643	NA	NA	0.608632583561542	0.745390056992892	81.7759598451944
a7769	loss_cnaOV55	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	1.11582342744124	1.81362759260241	-0.697804165161174	1.07501726945276	2.52298515116027	0.299014044962092	0.649109725945514	0.276578784001273	0.669701699601794	NA	NA	0.61534862455976	0.424155657441833	81.7759598451944
a7770	gain_cnaOV94	273	CUDC-101	HDAC, EGFR	6	25	1.63315443905142	NA	-0.221649228195874	0.199607617399664	-0.421256845595538	1.01828654107705	1.72803155934525	0.258774724966501	0.413691852540811	0.243778444506622	0.669739813128249	NA	NA	0.463322828167097	0.449796146173765	81.7759598451944
a7771	loss_cnaOV54	1066	AZD6482	PI3Kbeta	11	22	1.6094379124341	NA	2.66309523793943	2.23712284991499	0.425972388024434	1.43446793168921	1.23278328070678	0.327353087211735	0.296954974464165	0.345537122940389	0.669752714860461	NA	NA	0.111076704035576	0.411261710642622	81.7759598451944
a7772	loss_cnaOV34	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.54015909486701	4.37202346995181	0.168135624915206	1.27356855000701	0.787037289970589	0.194303243389559	0.132019297205699	0.213631078295527	0.669914863608544	NA	NA	0.86991449291348	0.78767614098506	81.7852335867672
a7773	SMAD4_mut	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	1.38701535926715	1.5837309380603	-0.196715578793148	2.34406671819307	1.57059291272117	0.120419075410646	0.0839206398292223	0.125249246446887	0.670064976354352	NA	NA	0.0797218232595592	0.89901775636218	81.7924462972341
a7774	loss_cnaOV36	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.77974914470769	3.37165871437387	0.408090430333822	1.23985843829954	1.22424196892585	0.333056400612639	0.329142761566811	0.333341317069763	0.670148995379887	NA	NA	0.328252843417867	0.632816449166972	81.7924462972341
a7775	SMARCA4_mut	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	3.2370344398682	3.97389374160162	-0.736859301733414	1.36400920584296	1.73796481403305	0.429706951247503	0.540215783425034	0.423978262266133	0.670302584428891	NA	NA	0.148561145510714	0.456540542997567	81.7924462972341
a7776	gain_cnaOV95_(MECOM)	207	AS601245	JNK 	5	13	2.07944154167984	NA	2.20638287043591	1.911581199374	0.294801671061919	0.677382293408168	1.07796236682266	0.296855017790747	0.435207229256997	0.273480485159106	0.670660630123663	NA	NA	0.48203728767543	0.50189461204753	81.7924462972341
a7777	gain_cnaOV18_(CCNE1)	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-4.41676463637356	-4.71738574722766	0.300621110854102	1.73203268693529	2.15154193787844	0.144275699729521	0.173565495109697	0.139723565486497	0.670678586144118	NA	NA	0.352446814314371	0.780370643171755	81.7924462972341
a7778	KRAS_mut	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.51529857980018	2.3185461352194	0.196752444580779	0.801944686878916	0.890895992628862	0.22516090249997	0.245344158768006	0.220847827590066	0.670746793672112	NA	NA	0.609052623751256	0.587441499133836	81.7924462972341
a7779	SMARCA4_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.89619073970904	2.8604131828043	0.0357775569047454	1.39810186201362	0.750399331475027	0.0441775067366598	0.0255900931661852	0.0476780234257659	0.670750414697504	NA	NA	0.0198407132585238	0.968928397767536	81.7924462972341
a7780	loss_cnaOV87, loss_cnaOV88	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	1.79545403207556	1.39437627777928	0.401077754296286	1.5193073754701	1.82043480974788	0.222662106077784	0.263987235744304	0.220319756658484	0.67084422388619	NA	NA	0.615796569595784	0.702424458761495	81.7924462972341
a7781	loss_cnaOV83	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.88013817892061	1.71236886129604	0.167769317624575	1.5665761631625	1.7343564708163	0.0979028420785223	0.107092985052124	0.0967328922557726	0.670915829624748	NA	NA	0.230664080518491	0.835587800642986	81.7924462972341
a7782	loss_cnaOV20	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.69915598187553	1.25428237898692	0.444873602888614	1.29287135186374	1.2099238518171	0.365107558699396	0.344097347541427	0.367687274054884	0.670959360622689	NA	NA	0.0985256256474619	0.553664166607784	81.7924462972341
a7783	loss_cnaOV21, loss_cnaOV22	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.91190378105237	2.39079841171185	0.52110536934052	1.53138458234422	1.45678413276581	0.356463469842683	0.340283802872574	0.357709394013761	0.671086216086747	NA	NA	0.241581674716357	0.621469418381582	81.7924462972341
a7784	loss_cnaOV21, loss_cnaOV22	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.08541401977401	2.30403107075741	-0.218617050983406	0.981735353387551	1.84730026257344	0.121182370601649	0.222684301048191	0.118344080500944	0.671095303171412	NA	NA	0.111597510896042	0.758511309914532	81.7924462972341
a7785	loss_cnaOV102	300	CX-5461	RNA Pol I	3	28	2.32630161961136	NA	3.99367128585508	3.49072765059598	0.50294363525911	1.56848829660405	1.72702815104128	0.292994307866897	0.320655013077265	0.29121912978423	0.671112128919273	NA	NA	0.69947349616248	0.643259799556959	81.7924462972341
a7786	MLL2_mut	1061	SB590885	BRAF	3	30	1.6094379124341	NA	4.02850010195553	3.91744379648628	0.111056305469249	0.92739441394765	1.31502882407312	0.0858551984952963	0.119750888941108	0.0844516131024926	0.671180793595639	NA	NA	0.574313137605156	0.862448788702166	81.7924462972341
a7787	TP53_mut	308	XL-880	MET	22	10	1.63315443905142	NA	0.308448599712087	0.13132796290038	0.177120636811707	1.13874584514912	0.382284258161002	0.181572743171848	0.155540094891421	0.463321816241544	0.67142881322958	NA	NA	0.369795256079872	0.518929054703277	81.7988711029265
a7788	loss_cnaOV36	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.68256631003563	4.49335392060543	0.189212389430199	2.08240514575263	0.7769191153376	0.203909906580209	0.0908624288679487	0.243541941104099	0.671646430596826	NA	NA	0.529776795536983	0.889833361303243	81.7988711029265
a7789	gain_cnaOV4_(KRAS)	1495	AZD-2281	PARP1, PARP2	7	26	2.30258509299405	NA	3.43714038263941	3.5946468037644	-0.157506421124985	0.75327633957607	0.958336072665127	0.170791897600999	0.209095139260084	0.164354056596201	0.671690553173828	NA	NA	0.144096164679889	0.652677775943437	81.7988711029265
a7790	loss_cnaOV59	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-2.55817614431777	-1.91140644407078	-0.646769700246995	3.05916735186195	1.89645761544665	0.317327757299928	0.21142017609901	0.341040946541096	0.671788354149278	NA	NA	0.279769071389404	0.705437334158596	81.7988711029265
a7791	loss_cnaOV16, loss_cnaOV17	1058	GDC0941	PI3K (class 1)	6	27	1.38629436111989	0.693147180559945	1.18938233832806	0.767090813847084	0.422291524480975	1.18172881912116	1.37543124225814	0.313720514696139	0.357350618558181	0.307024816295194	0.671798550524126	NA	NA	0.164569818350052	0.464063961262513	81.7988711029265
a7792	loss_cnaOV39	219	AT-7519	CDK9	9	23	2.32630161961136	NA	1.41278660576377	1.53093770182948	-0.118151096065716	1.77598805981	1.69625796122609	0.0687772225261364	0.0665269653211273	0.0696539670064767	0.671798701259669	NA	NA	0.317636042204808	0.866401816543012	81.7988711029265
a7793	loss_cnaOV83	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	2.02825746916665	1.47955392354507	0.548703545621585	1.03607697531165	1.6938787896685	0.338358649966192	0.529597277708574	0.323933181623325	0.672015384975988	NA	NA	0.0797332056499437	0.359181373639627	81.7988711029265
a7794	PIK3CA_mut	1007	Docetaxel	Microtubules	7	24	-4.38202663467388	NA	-5.23582621714526	-4.4772933762404	-0.758532840904858	0.796589372407434	1.5127259192538	0.543729867379387	0.952225660019085	0.501434417993596	0.672059264274459	NA	NA	0.136684179093737	0.0942109453796696	81.7988711029265
a7795	PIK3CA_mut	258	STF-62247	stimulates autophagy	6	25	2.32630161961136	NA	4.14563664804838	4.57201405266028	-0.4263774046119	0.652403187322866	0.661158451608935	0.646362073716306	0.653548929399836	0.644894432755577	0.672097915199024	NA	NA	0.0541596670901052	0.191083159721935	81.7988711029265
a7796	loss_cnaOV55	326	GSK690693	AKT	7	25	2.32630161961136	NA	4.11717327243401	4.16166335407805	-0.0444900816440414	1.78322165508372	1.38044477720331	0.0302683164971242	0.0249492717392739	0.0322288021793783	0.672101378426521	NA	NA	0.0945632586077663	0.952768607001072	81.7988711029265
a7797	loss_cnaOV83	272	AR-42	HDAC	5	25	1.63315443905142	NA	0.522430010877702	0.249631327733606	0.272798683144096	1.41501228964828	1.92043406364918	0.146928712733118	0.192788914371835	0.142050533422495	0.672181828389416	NA	NA	0.487544409026589	0.722907066442595	81.7988711029265
a7798	PIK3R1_mut	1502	Bicalutamide	ANDR (androgen receptor)	5	27	2.30258509299405	NA	4.58192219721987	4.50399048845148	0.0779317087683911	0.311276201652724	0.636543420815565	0.129156078280647	0.250361924087392	0.122429525182338	0.672476428994558	NA	NA	0.616180598543562	0.682015291734645	81.8109704401613
a7799	loss_cnaOV38	238	CAL-101	PI3Kdelta	8	24	2.99573227355399	2.32630161961136	4.55904115625558	4.32994905009024	0.229092106165342	0.731298677168221	1.05411380032477	0.231811876012038	0.313267497012912	0.21733147416793	0.672592591081049	NA	NA	0.512824613856123	0.504745528003157	81.8109704401613
a7800	gain_cnaOV96	133	Doxorubicin	DNA intercalating	4	15	0.0237165266173161	NA	-1.26446970914949	-1.6543515226356	0.389881813486109	0.506778115300338	1.43481197737577	0.295508366065861	0.769334353072938	0.271730247331215	0.672595946854034	NA	NA	0.623994082726189	0.398791465538298	81.8109704401613
a7801	loss_cnaOV57_(ZNRF3)	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	4.54695096856259	4.41464474320802	0.132306225354571	1.21449351892716	0.669892029427213	0.17817840654282	0.108939424782971	0.197503805900928	0.672811603032153	NA	NA	0.525678692340483	0.8437296880323	81.8109704401613
a7802	loss_cnaOV39	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.73758047929835	-1.51323209140288	-0.224348387895473	2.29798005959047	0.821059765783356	0.169203263527326	0.0976285181236319	0.273242457181454	0.672983802858255	NA	NA	0.623999063624848	0.84053873934634	81.8109704401613
a7803	gain_cnaOV49	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.21575246748247	1.52687548936223	-0.311123021879761	0.944920322984838	1.75839676196564	0.181285652352573	0.329258472182054	0.176935620338592	0.673026455971354	NA	NA	0.317647913050532	0.652491915296519	81.8109704401613
a7804	loss_cnaOV34	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	-0.0991471109217094	-0.374248713804029	0.27510160288232	1.04511457166177	1.46192036718734	0.19441060160278	0.263226262786575	0.188178240796796	0.673052808129698	NA	NA	0.889314928764715	0.627611996365362	81.8109704401613
a7805	loss_cnaOV59	1024	CEP-701	FLT3, JAK2, NTRK1, RET	4	27	0.693147180559945	NA	0.35867927461752	-0.234289489470618	0.592968764088137	2.66733698788869	1.43765902259839	0.368520307139723	0.222307405018778	0.412454382275166	0.673067787945608	NA	NA	0.101656453218204	0.69051794539571	81.8109704401613
a7806	gain_cnaOV50	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	4.42444928182787	4.54927801841345	-0.124828736585586	1.27236925491667	0.993346662084915	0.12182291496948	0.098107319163226	0.12566482714462	0.673108073860135	NA	NA	0.192741724960777	0.861005297534847	81.8109704401613
a7807	loss_cnaOV41	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	1.24920846974562	0.9588016887163	0.290406781029324	1.1370783577908	1.61331361279701	0.186367517158745	0.255397333912456	0.180006403420749	0.673173519671636	NA	NA	0.791662183791056	0.640109039268101	81.8109704401613
a7808	loss_cnaOV52, loss_cnaOV53	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	-1.38629436111989	0.693147180559945	-2.32748654337262	-2.04710933938207	-0.280377203990549	1.66004048095669	1.14466812113122	0.216104246504023	0.168897811352748	0.244941917062795	0.673236929722298	NA	NA	0.608657477159075	0.649774147642005	81.8109704401613
a7809	loss_cnaOV33_(ZFHX3)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	1.44153805105432	1.13012710035927	0.311410950695051	1.95751566642457	1.44383257775221	0.207435069844438	0.159084780794551	0.215683560194951	0.673315931440633	NA	NA	0.81364727749146	0.776483934782412	81.8109704401613
a7810	loss_cnaOV33_(ZFHX3)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	-0.064251209249686	-0.369575679452504	0.305324470202818	1.2034261357376	1.43579785145707	0.215780206398629	0.253712680102032	0.212651432715943	0.67346363656123	NA	NA	0.889315812991514	0.665345037177168	81.8122325012438
a7811	ARID1A_mut	221	TAK-715	p38a	8	24	2.99573227355399	2.32630161961136	4.07047028513345	4.34709690168881	-0.27662661655536	0.453817333586937	0.990697412768344	0.309176704156837	0.609554981888692	0.279224123319724	0.673498767177546	NA	NA	0.522882007919325	0.293554632347977	81.8122325012438
a7812	loss_cnaOV82	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.926176712622729	0.527084308833389	0.39909240378934	1.96147770970641	1.14224848709301	0.328042217126989	0.203465174146218	0.349391930301453	0.673606387512257	NA	NA	0.432442744045175	0.760207005377811	81.8144521860014
a7813	loss_cnaOV83	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	-0.0996957269190523	-0.374150746661647	0.274455019742594	1.7666795910786	1.35524549585786	0.193951314931548	0.155350761467184	0.202513139192444	0.673735630142279	NA	NA	0.889316397635538	0.754784780387727	81.8144521860014
a7814	loss_cnaOV38	300	CX-5461	RNA Pol I	8	23	2.32630161961136	NA	3.80640898103169	3.44652679243474	0.359882188596953	2.26766135659941	1.49805763670676	0.209754866008031	0.158701910031501	0.240232538307469	0.673775720387859	NA	NA	0.699489494831514	0.685337083694091	81.8144521860014
a7815	loss_cnaOV54	179	5-Fluorouracil	DNA antimetabolite	10	21	3.46573590279973	NA	4.25627202439689	3.73416227811815	0.522109746278738	1.26968118554143	1.87604544788354	0.305145950386999	0.411213265364796	0.278303357132289	0.674084207854037	NA	NA	0.148592327843702	0.371177200104175	81.8414371491741
a7816	gain_cnaOV18_(CCNE1)	293	MP470	PDGFR	4	28	2.99573227355399	NA	4.34282946029225	4.00730176572071	0.33552769457154	1.28375926218374	1.82435714377334	0.188741463363919	0.261363407030684	0.183915575805274	0.674509760034959	NA	NA	0.623335713354744	0.66473446179401	81.8826263675518
a7817	loss_cnaOV82	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	4.16976713231494	3.59214294188055	0.577624190434392	1.5241339807434	2.06828908806743	0.283630095969514	0.378985179605178	0.279276332194989	0.674599114856956	NA	NA	0.748197084216903	0.59223174401246	81.8829973340032
a7818	loss_cnaOV21, loss_cnaOV22	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.0749773101361	2.11934563904073	-0.0443683289046346	0.269286671928449	0.578266150265558	0.0787414865439055	0.164762439176431	0.0767264846546167	0.67477685964062	NA	NA	0.042933350666684	0.824413622993704	81.8940956273229
a7819	gain_cnaOV94	207	AS601245	JNK 	3	15	2.07944154167984	NA	2.15788474137248	1.96058771466161	0.197297026710877	0.695382506309252	1.03609248900281	0.197322059212906	0.283724460884172	0.190424145339346	0.675097242207127	NA	NA	0.482113481756908	0.703247468063951	81.9148382499035
a7820	gain_cnaOV4_(KRAS)	184	BMS-754807	IGF1R	6	11	0.940007258491471	NA	0.689842461537532	0.865175945908786	-0.175333484371254	0.7343892910451	1.22139009672667	0.161798465411586	0.238747332660228	0.143552403807062	0.675142586706654	NA	NA	0.358470550497732	0.717220981361756	81.9148382499035
a7821	loss_cnaOV40	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	2.92568007636015	2.30809262886006	0.617587447500097	2.25736265265725	1.35585882354613	0.39139430909474	0.273588050539024	0.455495392864612	0.675206768738215	NA	NA	0.229709727796495	0.586612923506061	81.9148382499035
a7822	loss_cnaOV59	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.4067032528965	4.54504506244106	-0.138341809544555	1.51184431158962	0.922755263212363	0.139019763753802	0.0915053279521197	0.149922536407919	0.675530773364238	NA	NA	0.327012865300187	0.868703001381704	81.9226791644767
a7823	loss_cnaOV33_(ZFHX3)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.35562444621168	1.19680901750629	0.158815428705387	1.03393179839177	1.268396415265	0.127293334591632	0.153603389461874	0.125209616484296	0.675772001756227	NA	NA	0.268431568774706	0.792598518619742	81.9226791644767
a7824	SMAD4_mut	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	2.49199285143486	2.25548975090707	0.236503100527795	1.03874277291195	1.86688633726122	0.131139924908609	0.227682065950548	0.126683181406079	0.675796821909725	NA	NA	0.111629076044303	0.717634008469437	81.9226791644767
a7825	gain_cnaOV72_(ASXL1)	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	4.06985050426658	3.87780466916236	0.192045835104224	1.23912637410128	1.77603258804814	0.111122012109682	0.154984866046057	0.10813193203582	0.675849832910348	NA	NA	0.148606733869357	0.796822854340701	81.9226791644767
a7826	MLL2_mut	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-3.70936120003285	-4.09731704324002	0.387955843207172	2.1168103572649	1.48052146719327	0.25308515498031	0.183273783537437	0.262039998611198	0.675909054299446	NA	NA	0.864541712250761	0.783711923413861	81.9226791644767
a7827	KRAS_mut	238	CAL-101	PI3Kdelta	7	25	2.99573227355399	2.32630161961136	4.19398004569695	4.44132984529326	-0.247349799596311	1.17646929332467	0.934879684902814	0.250370461483536	0.210247561070894	0.264579286073613	0.675928450746919	NA	NA	0.512852786716518	0.621561730753603	81.9226791644767
a7828	gain_cnaOV50	1047	Nutlin-3a	MDM2	4	29	2.07944154167984	1.38629436111989	3.60716429199525	3.76708482174589	-0.159920529750638	1.93701751360358	1.52797873921426	0.101716318234391	0.0825601878287232	0.104661488832544	0.67603669855017	NA	NA	0.166476703261989	0.88272765479731	81.9226791644767
a7829	loss_cnaOV39	1377	Afatinib (rescreen)	ERBB2, EGFR	10	23	2.30258509299405	NA	2.78046120117054	2.60060935441245	0.179851846758086	1.61387180381095	1.75438238440991	0.104883610905954	0.111441222489537	0.102515761875128	0.676187797586549	NA	NA	0.641095085138923	0.777714949635682	81.9226791644767
a7830	gain_cnaOV51_(MYC)	330	XMD13-2	RIPK	8	24	2.32630161961136	NA	4.24581461830562	4.03009139059501	0.21572322771061	1.02693787527977	1.15370397214304	0.191685293820451	0.210064535453851	0.186983171523538	0.676210134593937	NA	NA	0.820213613967001	0.626225383151736	81.9226791644767
a7831	loss_cnaOV39	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	9	23	2.32630161961136	NA	5.30080074828947	5.08047153623531	0.220329212054162	0.753529815386592	0.506483277197813	0.378120800173194	0.292396143530332	0.43501774288218	0.676257652568983	NA	NA	0.0121386852192268	0.435944282596921	81.9226791644767
a7832	gain_cnaOV95_(MECOM)	1067	CCT007093	PPM1D	8	25	1.88706964903238	NA	4.41731398236505	4.51290048545798	-0.095586503092929	0.78743087211822	0.678508855087994	0.135664990772819	0.121390342285917	0.140877311145088	0.676293645543407	NA	NA	0.0823795852027953	0.763611820299331	81.9226791644767
a7833	SMAD4_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.63264345585677	5.72360065357377	-0.0909571977169987	0.62157273085229	0.469498447583401	0.189047350298015	0.146333957720893	0.193732691098709	0.676307489351062	NA	NA	0.383265785798032	0.826195826817111	81.9226791644767
a7834	gain_cnaOV19	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	4.53880575513894	4.16167505450594	0.377130700633002	1.27642643849452	0.950098730092779	0.386698821707863	0.295458233439451	0.396938432489194	0.676531558397118	NA	NA	0.0488279890862885	0.663403179172911	81.9354214772796
a7835	loss_cnaOV36	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.30761828717964	3.58125182083872	-0.273633533659077	1.235776515001	0.941894528719487	0.283770613921461	0.221426390886588	0.290513985712481	0.676585391167159	NA	NA	0.729325685585005	0.741769321798478	81.9354214772796
a7836	loss_cnaOV85	133	Doxorubicin	DNA intercalating	6	13	0.0237165266173161	NA	-1.33038840744158	-1.68390932549866	0.353520918057078	1.65037220383843	1.1525474303329	0.268098568579857	0.214206781497446	0.306730038827963	0.676721844639605	NA	NA	0.624046687853777	0.649226255143948	81.9390863124187
a7837	PTEN_mut	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.63720264889171	2.35872347017433	0.278479178717373	0.506348858501351	0.982354598349321	0.294500297324944	0.549974931397284	0.283481320477666	0.676816379963236	NA	NA	0.735641799553711	0.40503295765553	81.9390863124187
a7838	loss_cnaOV21, loss_cnaOV22	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.66114241039995	4.35888549037967	0.302256920020282	1.3956983206401	0.953765819646467	0.305498729198533	0.216563218247378	0.316908945355496	0.676880519329456	NA	NA	0.512860761233888	0.746402636701433	81.9390863124187
a7839	loss_cnaOV41	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	4.17533743379061	4.00627368901727	0.169063744773339	1.14742316502161	1.55677057188115	0.112065005719442	0.14734210527304	0.108599011201148	0.676997284515789	NA	NA	0.331308878545442	0.784168720542698	81.9390863124187
a7840	SMARCA4_mut	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.13766591570855	2.11307677848349	0.0245891372250626	0.48864076089637	0.568378555933928	0.0436306593634308	0.05032150240589	0.0432619017173495	0.677047444168346	NA	NA	0.0429419041425624	0.940737993519764	81.9390863124187
a7841	PIK3R1_mut	281	CH5424802	ALK	5	27	1.63315443905142	NA	3.80115459770968	3.95102251799243	-0.149867920282754	1.18657372612383	0.63573655393175	0.204323046400994	0.126303083393163	0.235739032710778	0.677154165372106	NA	NA	0.955934264701202	0.795514579093028	81.9415504262118
a7842	loss_cnaOV35	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	4.7470077367478	4.55907227746689	0.187935459280911	0.966286927287596	0.947055307221111	0.197901371376668	0.194492395554241	0.19844190497423	0.677328141863895	NA	NA	0.943328561846475	0.703667361852736	81.9432890902521
a7843	loss_cnaOV84	271	VNLG/124	HDAC, RAR 	6	25	1.63315443905142	NA	4.28759980851231	4.33937590050831	-0.0517760919960049	0.788468393036515	0.542176843506441	0.087460072899091	0.0656666677488581	0.0954966863969168	0.677422386686957	NA	NA	0.255616506858604	0.883698795753855	81.9432890902521
a7844	loss_cnaOV35	1248	FK866	NAMPT	5	27	0	NA	-0.84387390618802	-1.86844734980197	1.02457344361395	3.67313534534499	2.58351807140206	0.372054801686296	0.278937024444909	0.396580714861392	0.677448348712358	NA	NA	0.0452366284546307	0.57777558421226	81.9432890902521
a7845	ARID1A_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	8	24	0.246860077931526	2.32630161961136	1.24241765735471	0.92476444521794	0.31765321213677	1.71870907077203	1.50241451117298	0.204203007845563	0.1848208155404	0.211428477144279	0.677747857704553	NA	NA	0.79168086890196	0.649992525210326	81.9432890902521
a7846	gain_cnaOV50	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	2.57799344777511	2.27625222916106	0.301741218614041	1.07732059178604	1.48837324151047	0.207737491484901	0.280084889228561	0.202732224820046	0.677966401743932	NA	NA	0.821525842969398	0.641320900541053	81.9432890902521
a7847	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.42673009092885	2.13891337471141	0.287816716217439	0.862423974208309	1.33736752387598	0.219681923334704	0.333729957451206	0.215211384364474	0.678151870284009	NA	NA	0.687547063684565	0.640272910098263	81.9432890902521
a7848	loss_cnaOV41	272	AR-42	HDAC	5	25	1.63315443905142	NA	-0.114500554867593	0.377017440882665	-0.491517995750258	1.53625213538033	1.89721088460327	0.265690806989813	0.319946175780951	0.259073991056635	0.678250356998267	NA	NA	0.487601032185134	0.551850451001586	81.9432890902521
a7849	MLL2_mut	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	2.12705144506312	3.07245576446416	-0.945404319401044	0.744799667033919	0.988709951391504	0.969827269787768	1.26934041628403	0.956199862326143	0.678250765034716	NA	NA	0.0886847258335996	0.143573347575556	81.9432890902521
a7850	KRAS_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	3	16	2.77258872223978	NA	0.426164881012513	-0.756042767265282	1.18220764827779	3.66100228853007	1.42261481866046	0.644702442773526	0.32291912299035	0.831010356964347	0.678272682322872	NA	NA	0.0437514939919953	0.633989706450126	81.9432890902521
a7851	loss_cnaOV54	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	6	17	2.30258509299405	NA	1.47326381983781	1.59485988512745	-0.121596065289634	1.08648657977399	1.08213309239044	0.112259320212404	0.111916766901004	0.112367014875247	0.678379046086541	NA	NA	0.456254761983264	0.818898900222232	81.9432890902521
a7852	loss_cnaOV44	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.60246966182076	3.95386337376349	-0.351393711942732	1.00732291982171	1.24174808755146	0.2863798768543	0.348839190519883	0.282983090906649	0.678863422680075	NA	NA	0.699741093163012	0.618373645049399	81.9432890902521
a7853	loss_cnaOV54	185	OSI-906	IGF1R	6	12	0.940007258491471	NA	2.34623745525033	2.13902704515569	0.20721041009464	1.3281495067311	1.31799213680471	0.15683800902615	0.156014371156629	0.157216727102025	0.678943291610459	NA	NA	0.687794193135908	0.760821365053294	81.9432890902521
a7854	loss_cnaOV81_(RB1)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	1.13398243178051	0.831434110365527	0.302548321414982	1.40233000410737	1.234566722035	0.241583560767494	0.215746878786612	0.245064374419777	0.678987214161148	NA	NA	0.845403244227557	0.704833327251967	81.9432890902521
a7855	loss_cnaOV59	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	5.0557826301897	4.83210406297764	0.223678567212064	0.492858862112255	0.633450709502495	0.360291934702451	0.453838988008536	0.353111242684911	0.67909490057631	NA	NA	0.0503715497572567	0.454807938582318	81.9432890902521
a7856	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.65386516948664	3.45802349680719	0.195841672679451	0.648149285708907	1.17910856981374	0.174714094878148	0.302155193251892	0.166092994057695	0.67912828337726	NA	NA	0.727702668849756	0.608841065238756	81.9432890902521
a7857	gain_cnaOV51_(MYC)	310	YM201636	FYV1	8	24	1.63315443905142	NA	2.21962966092284	2.40267887512651	-0.183049214203667	0.829319288821409	0.883269766274686	0.210164590984736	0.220722243737762	0.207240439096769	0.679203992687588	NA	NA	0.651648175836008	0.604014270952569	81.9432890902521
a7858	PIK3CA_mut	1170	CCT018159	HSP90	7	26	2.30258509299405	NA	3.23419964744948	3.81900975405937	-0.584810106609891	1.02842011745633	1.24883836690756	0.483587406002244	0.56864903426466	0.468283263956751	0.679230381660229	NA	NA	0.199578473347116	0.228656390791799	81.9432890902521
a7859	loss_cnaOV84	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	6	25	2.32630161961136	NA	2.01549943602054	2.36062457397435	-0.345125137953809	0.585778427868192	1.533465702468	0.243720984285446	0.589173519430911	0.225062182609207	0.679468555630564	NA	NA	0.531340156816577	0.384296484098182	81.9432890902521
a7860	gain_cnaOV95_(MECOM)	1013	Nilotinib	ABL	5	16	0.693147180559945	NA	3.43427766717882	3.19152075772398	0.242756909454837	1.4188089459578	0.908532797834674	0.234086547476162	0.171099082893756	0.26719663839699	0.679471260642507	NA	NA	0.567578907651476	0.733217135823566	81.9432890902521
a7861	gain_cnaOV26	155	AP-24534	ABL	3	16	-0.669430653942629	NA	1.01742183169556	0.745637529922359	0.271784301773198	1.8757506151454	1.16699439789562	0.213825192796197	0.144893622626978	0.232892550524057	0.679592928187041	NA	NA	0.586445315081523	0.82846563547583	81.9432890902521
a7862	KRAS_mut	344	THZ-2-49	CDK9	7	25	2.99573227355399	NA	2.72700043267399	2.5481008202896	0.178899612384385	2.16333233279981	2.39733507018904	0.0760499095417731	0.0826963151578524	0.0746243671187265	0.679603765426335	NA	NA	0.387542719152285	0.853888059786473	81.9432890902521
a7863	RB1_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.34979145266113	4.52900836960984	-0.179216916948708	1.72366611761912	0.839709843092286	0.193099432276581	0.10397426457292	0.213427195623586	0.679626323498238	NA	NA	0.529844648644016	0.874514983374771	81.9432890902521
a7864	loss_cnaOV55	1527	GDC0941 (rescreen)	PI3K	7	24	1.38629436111989	NA	0.248342773998591	0.42134664944309	-0.173003875444498	0.832620634520322	0.936393033088426	0.188891945194916	0.207782354017886	0.184755620056136	0.679915567704238	NA	NA	0.909965890804783	0.647747878706216	81.9432890902521
a7865	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	254	AC220	FLT3	7	25	0.0237165266173161	NA	2.42241298850778	2.53557328162845	-0.113160293120666	0.600732276453291	0.640519261202741	0.178835465601287	0.188370589622321	0.176669617878747	0.679929433281437	NA	NA	0.858575343555593	0.673307221352712	81.9432890902521
a7866	gain_cnaOV48_(SOX17)	292	Masitinib	KIT	3	29	2.99573227355399	NA	3.89476353947838	4.02580561495468	-0.1310420754763	1.08721551143659	1.05595591038276	0.123850262119838	0.120529990694437	0.124098055787955	0.679994305585903	NA	NA	0.105806618441183	0.857649922217519	81.9432890902521
a7867	gain_cnaOV95_(MECOM)	231	FMK	RSK	5	15	2.99573227355399	2.32630161961136	5.32333686806567	5.21602825094378	0.107308617121885	0.645715991158852	0.778437729840317	0.142892616741639	0.166185472546995	0.137851253874729	0.680008973134429	NA	NA	0.128500671467254	0.767911976396128	81.9432890902521
a7868	gain_cnaOV94	293	MP470	PDGFR	7	25	2.99573227355399	NA	3.7443555249273	4.13461114427431	-0.390255619347014	2.15238526487947	1.66548554664091	0.220036947732168	0.181313088188637	0.234319427228963	0.680131936086427	NA	NA	0.623374508677953	0.668675383041528	81.9432890902521
a7869	gain_cnaOV95_(MECOM)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	NA	1.35659724410698	1.17108725358693	0.185509990520047	1.15949395294462	1.27022598501523	0.148874578665624	0.159992201812635	0.146044871313054	0.680477233326665	NA	NA	0.268473961286449	0.706781950017884	81.9432890902521
a7870	loss_cnaOV82	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.77020465858629	3.37264607500712	0.397558583579177	1.23931156753256	1.22461794692592	0.324377945281081	0.320789859462627	0.32463886763798	0.680488303317476	NA	NA	0.328351732360685	0.64103646235777	81.9432890902521
a7871	gain_cnaOV72_(ASXL1)	173	FH535	unknown 	4	14	3.46573590279973	NA	2.48332155146727	2.50068491254632	-0.0173633610790489	1.22042478541634	1.51052454947127	0.0118884250622917	0.0142273094471164	0.0114949214728927	0.680699495393667	NA	NA	0.123406594882724	0.98184430426647	81.9432890902521
a7872	loss_cnaOV56	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	3.08626483008488	2.8866048035268	0.199660026558078	1.40558093711243	1.24524357611208	0.158892956776944	0.142048046673322	0.160338130136322	0.680720415643456	NA	NA	0.233136156645952	0.832115989212679	81.9432890902521
a7873	loss_cnaOV102	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.96940071858866	4.79545811748578	0.173942601102881	0.59868676510391	0.7613395579403	0.231432231889275	0.290540247825072	0.228469149262989	0.680777074305837	NA	NA	0.765975790284521	0.676109169781966	81.9432890902521
a7874	NF1_mut	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	4.89326751031379	4.8553205086742	0.0379470016395933	0.882093964523161	0.589995209235105	0.060678795514624	0.0430192282974145	0.0643174741855776	0.680782395278553	NA	NA	0.0503787293523906	0.938203442773678	81.9432890902521
a7875	TP53_mut	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	12	7	2.77258872223978	NA	-0.754768283371364	-0.251567176107229	-0.503201107264135	1.69791157737074	2.15494718812989	0.268803565239864	0.296364730631825	0.233509716635248	0.680854160060708	NA	NA	0.0437689000326417	0.607686983032428	81.9432890902521
a7876	gain_cnaOV51_(MYC)	1375	Temozolomide	DNA akylating agent	8	25	3.40119738166216	NA	6.04236884081015	5.91677559072667	0.125593250083478	0.827468230017187	0.666553754736572	0.177868433282776	0.151780147596566	0.188421787726803	0.680917665696506	NA	NA	0.908994231413431	0.704181493002941	81.9432890902521
a7877	loss_cnaOV56	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	2.32068571592233	1.65951084484604	0.661174871076293	1.13112769802572	1.62917853848029	0.413281857653926	0.584527168975096	0.405833280674714	0.681206546249327	NA	NA	0.0418873686514016	0.427794762271954	81.9432890902521
a7878	loss_cnaOV82	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.33479364073056	2.95168154489742	0.383112095833139	1.29679541880016	0.984925731089765	0.380085673088452	0.295429865250148	0.388975618912146	0.681270802326696	NA	NA	0.0887022455775425	0.663456437865934	81.9432890902521
a7879	ARID1A_mut	271	VNLG/124	HDAC, RAR 	8	23	1.63315443905142	NA	4.13771006616817	4.39601373193202	-0.258303665763845	0.42125897558425	0.622972601733275	0.444788409303643	0.613170711450361	0.414630860241968	0.681303726833504	NA	NA	0.255653481459375	0.207365399778869	81.9432890902521
a7880	loss_cnaOV102	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	3.35287750489929	3.2406041292747	0.112273375624585	1.19649302048596	1.0877820750768	0.102498579558958	0.0938353786459907	0.103213114278113	0.681326123617578	NA	NA	0.0632179560932237	0.888407123486945	81.9432890902521
a7881	gain_cnaOV94	1010	Gefitinib	EGFR	7	23	-0.693147180559945	NA	1.10473499625133	0.870853703537084	0.233881292714247	1.0917578452888	1.32263993882851	0.183194197013585	0.214224512993885	0.176829147410594	0.681435504638421	NA	NA	0.95762747606776	0.645992564135599	81.9432890902521
a7882	loss_cnaOV41	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.42301877474172	4.52947425269009	-0.106455477948369	0.580924017016111	0.605407310248294	0.176541993227002	0.183251982755288	0.175841084417545	0.681596015014718	NA	NA	0.616244562928704	0.750290452638791	81.9432890902521
a7883	loss_cnaOV55	185	OSI-906	IGF1R	4	14	0.940007258491471	NA	1.91673940574026	2.29134226074351	-0.374602855003249	1.33752418748132	1.3096182503514	0.284891681802312	0.280071836090427	0.286039733260233	0.681618324685579	NA	NA	0.687824679821685	0.641641621003403	81.9432890902521
a7884	loss_cnaOV57_(ZNRF3)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	0.848981579770342	1.21185902743292	-0.362877447662574	2.40734913282445	1.36745196232983	0.241928902128663	0.150737357832606	0.265367601684751	0.681643704024259	NA	NA	0.813676593102449	0.785746380903358	81.9432890902521
a7885	gain_cnaOV26	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.11701541425028	5.1450691663885	-0.0280537521382227	0.311970787300288	0.606607906671405	0.04742423904602	0.0899242918896106	0.0462469279244314	0.681679836494242	NA	NA	0.012147001448754	0.901587706488751	81.9432890902521
a7886	loss_cnaOV52, loss_cnaOV53	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	2.59516069580552	2.21228746190155	0.382873233903973	0.701965189524661	1.35501563585931	0.310551823348644	0.545430513674385	0.28256001168663	0.681796640199785	NA	NA	0.392024131532671	0.437648535642626	81.9432890902521
a7887	loss_cnaOV35	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	2.78974225659654	2.19387367496649	0.595868581630053	1.11603025016655	1.87115113397763	0.33257360442111	0.533917948497482	0.318450268826429	0.681865683406875	NA	NA	0.111668992908791	0.356287015029159	81.9432890902521
a7888	gain_cnaOV26	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.80119667378408	4.41539744519851	0.385799228585577	0.213421094904443	1.0185107538208	0.391469001463349	1.80769023211278	0.378787584852006	0.681974950520256	NA	NA	0.0318322580741706	0.106594971294796	81.9432890902521
a7889	PTEN_mut	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	3.71953444956236	4.29964032720317	-0.580105877640807	1.26249535642909	0.929518193961018	0.600047183467581	0.459491494116549	0.624093085438987	0.681982059330868	NA	NA	0.211041688669768	0.432623606986697	81.9432890902521
a7890	loss_cnaOV83	305	TPCA-1	IKK	5	27	2.99573227355399	NA	3.11356772831534	3.36438524904833	-0.250817520732993	1.18587595039634	1.24481230742169	0.20274367754105	0.211504011569815	0.201490232091694	0.682172137333776	NA	NA	0.993633254455334	0.682120654239806	81.9432890902521
a7891	loss_cnaOV41	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.34476104021291	3.91406260208493	0.430698438127973	1.50977582532803	1.12162716880681	0.368818549026444	0.285273105385957	0.383994298734893	0.682200897220966	NA	NA	0.0838865356437325	0.616323466068766	81.9432890902521
a7892	loss_cnaOV42	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.34476104021291	3.91406260208493	0.430698438127973	1.50977582532803	1.12162716880681	0.368818549026444	0.285273105385957	0.383994298734893	0.682200897220966	NA	NA	0.0838865356437325	0.616323466068766	81.9432890902521
a7893	loss_cnaOV36	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	1.23990365389349	0.639898593027824	0.600005060865665	2.3348528750495	2.32184921110658	0.258320192511563	0.256977673958555	0.258416893739497	0.682251074704462	NA	NA	0.946022690803306	0.706279641836424	81.9432890902521
a7894	loss_cnaOV83	1031	Elesclomol	HSP70	5	26	-1.6094379124341	NA	-3.82172900534177	-4.10555060708116	0.283821601739394	2.18461620935488	1.40177153692672	0.185057547486954	0.12991828977741	0.202473508886942	0.682311824257889	NA	NA	0.864559339105531	0.791747534310571	81.9432890902521
a7895	loss_cnaOV81_(RB1)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	4.20680271779781	4.00781663932958	0.198986078468237	1.22403027785088	1.53677714461323	0.131916610717851	0.162566304174772	0.129482715932971	0.682400742669065	NA	NA	0.331359687149162	0.782077929022935	81.9432890902521
a7896	gain_cnaOV95_(MECOM)	1006	Cytarabine	DNA synthesis	8	23	0.693147180559945	NA	0.057175034948677	-0.169912546464611	0.227087581413288	1.5531975467553	1.16010418122174	0.179344075576149	0.146206502764368	0.195747576027297	0.682558371508212	NA	NA	0.767931090228489	0.713119887110486	81.9432890902521
a7897	MLL2_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.08734513281714	1.17592675720615	-0.0885816243890074	0.760758123241042	1.54281264907838	0.0588709735299875	0.116438617850868	0.0574156715929979	0.682585610455953	NA	NA	0.813679849533671	0.873558322621712	81.9432890902521
a7898	loss_cnaOV54	194	AUY922	HSP90	6	13	-1.36257783450257	NA	-2.66825087466803	-2.48899503843628	-0.179255836231752	1.31023940154219	2.25854749010665	0.088467194818646	0.13681151400329	0.0793677516266384	0.682647305273547	NA	NA	0.348012925085545	0.830518197622952	81.9432890902521
a7899	loss_cnaOV58	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.69667183276414	3.52947401859411	0.167197814170022	1.10407442143269	0.94267675353459	0.173126328966768	0.151437086961094	0.17736494884711	0.682674768086505	NA	NA	0.729356930648186	0.763112606739257	81.9432890902521
a7900	loss_cnaOV43_(NF1)	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.28012472525004	3.06383011728577	0.216294607964271	0.501451865307063	1.01252597816234	0.223784845423758	0.43133673025989	0.213618823249188	0.682846226255323	NA	NA	0.672817844079351	0.594955069043534	81.9432890902521
a7901	loss_cnaOV52, loss_cnaOV53	152	CP466722	ATM	8	24	2.77258872223978	NA	2.78170572742805	2.60198700420829	0.17971872321976	0.708322924202737	0.84688553135523	0.220065592732189	0.25372427896788	0.21221135155322	0.682977654092082	NA	NA	0.557258682493772	0.564026347763581	81.9432890902521
a7902	loss_cnaOV82	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	1.63828228600361	1.73262549805161	-0.0943432120480083	1.39700136042866	1.62708681866674	0.0585156427001848	0.0675326558157824	0.0579828998463123	0.683015292307611	NA	NA	0.0418943533283897	0.920789165070693	81.9432890902521
a7903	loss_cnaOV70	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.80747906639778	4.86550369258412	-0.0580246261863389	0.284717198635259	0.642722311631547	0.0928000019954789	0.203797404808946	0.090279464608975	0.683020355245116	NA	NA	0.0503881797786574	0.78763359568353	81.9432890902521
a7904	loss_cnaOV82	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.50832315624466	4.31017953196599	0.198143624278664	0.459334391562691	0.59777242210889	0.336252663309546	0.431371192574029	0.33146999920075	0.683057207347091	NA	NA	0.255670004350508	0.544687828579821	81.9432890902521
a7905	gain_cnaOV72_(ASXL1)	207	AS601245	JNK 	4	14	2.07944154167984	NA	2.25007437597183	1.92015517429673	0.329919201675105	0.682547095572637	1.05089742840424	0.332478519427581	0.483364743349046	0.313940440577612	0.683165348962678	NA	NA	0.48224873918083	0.47775781035127	81.9432890902521
a7906	gain_cnaOV95_(MECOM)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	0	NA	-2.27674179015697	-1.89798228536272	-0.378759504794256	2.11730183230689	2.02071735010702	0.18540050854646	0.178887817983694	0.187438141595704	0.683262573041078	NA	NA	0.279873274685852	0.664495457128466	81.9432890902521
a7907	PTEN_mut	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	3.41886423441969	3.96768120114596	-0.548816966726267	0.692853086814806	1.10015696857186	0.514088334098489	0.792111599371371	0.498853329483247	0.683277903846334	NA	NA	0.317988309616787	0.22668750383128	81.9432890902521
a7908	loss_cnaOV42	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	4.82782200771982	4.86466986618762	-0.0368478584678034	0.671503815510082	0.620046362268061	0.0589204985000875	0.0548736397570777	0.0594275859195722	0.68333303885274	NA	NA	0.0503894937310256	0.922749394585421	81.9432890902521
a7909	loss_cnaOV83	172	Embelin	XIAP	4	15	3.46573590279973	NA	3.2441343292331	3.05900791569267	0.185126413540428	1.53231364837468	0.794941519626005	0.191477251509237	0.120814960916645	0.232880544002186	0.683366680146804	NA	NA	0.67282356265637	0.828657731652342	81.9432890902521
a7910	loss_cnaOV39	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	2.88766416116598	3.00720207862142	-0.119537917455433	0.983832877344667	0.430157028285083	0.196719944841844	0.121502259385824	0.277893675088834	0.683466038450949	NA	NA	0.850454241964162	0.804118573956215	81.9432890902521
a7911	loss_cnaOV87, loss_cnaOV88	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	5.19831602217055	4.88015339188155	0.318162630289003	1.65883219602205	0.770816126786597	0.369120234037829	0.19179916513073	0.412760734022742	0.683500208257526	NA	NA	0.15564465504013	0.772546058684989	81.9432890902521
a7912	PIK3CA_mut	1264	SGC0946	Q8TEK3 (DOT1L)	7	26	-0.693147180559945	NA	1.82709712009395	2.19290851003741	-0.365811389943454	0.741646131659393	0.482058069688382	0.674815788515284	0.493242497098948	0.758853368391751	0.683714452779332	NA	NA	0.0429665966582624	0.253957268013165	81.9432890902521
a7913	PTEN_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	4.62265687588019	5.19620970484058	-0.573552828960395	0.51392327308253	0.569380537480489	1.01360835678333	1.11602812910224	1.00732777326455	0.683716244104012	NA	NA	0.0121500810325834	0.182697183703515	81.9432890902521
a7914	loss_cnaOV85	277	ABT-869	VEGFR and PDGFR family	7	25	0.0237165266173161	NA	2.69784080342694	2.72113048402914	-0.0232896806022063	0.807176776100005	0.499025658426201	0.0405711453868578	0.0288532590280085	0.0466703068448543	0.683731647048226	NA	NA	0.136895885835628	0.944100219392214	81.9432890902521
a7915	loss_cnaOV40	1004	Vinblastine	Microtubules	7	24	-2.30258509299405	NA	-2.86265526980569	-3.44717676985626	0.584521500050573	2.04732609333242	1.75693615417105	0.32102093497348	0.285504835772962	0.332693648919963	0.683867106758306	NA	NA	0.140814535036272	0.510872716097265	81.9432890902521
a7916	loss_cnaOV1	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	2.98396150317017	2.62222475512271	0.361736748047456	0.401709237579907	1.76849769458321	0.211105072689839	0.900493974763278	0.204544653439715	0.683906691629121	NA	NA	0.641144024201388	0.378578868537594	81.9432890902521
a7917	loss_cnaOV43_(NF1)	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.18264152689937	2.38918972799712	-0.206548201097749	1.10613844814628	0.829390217574274	0.23703486675459	0.186729067635152	0.249036215669197	0.683971086705097	NA	NA	0.651678500843407	0.707920343360481	81.9432890902521
a7918	loss_cnaOV54	158	PF-562271	FAK	5	13	0.940007258491471	NA	2.0274138193078	2.39021906901522	-0.362805249707425	1.23600622519416	1.45493218914718	0.258517657076184	0.293530277042441	0.249362308713567	0.684032067570542	NA	NA	0.748523179256551	0.609458917832851	81.9432890902521
a7919	loss_cnaOV58	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-2.49403408034735	-1.89976146619953	-0.594272614147818	2.6531961267263	1.93020177382595	0.291602364725893	0.223983673186298	0.307881083836059	0.6840713602112	NA	NA	0.279880446801922	0.653199304534288	81.9432890902521
a7920	loss_cnaOV55	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.28202478892912	3.51294832374852	-0.230923534819397	0.795327779445633	1.18048650041776	0.205783972328398	0.290350143409246	0.195617260119175	0.684088183472086	NA	NA	0.774394254908504	0.658778397822386	81.9432890902521
a7921	loss_cnaOV59	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.57492887306731	8.77545636744675	-0.20052749437944	0.974194590628023	1.27110523826343	0.161236979589386	0.205839260768393	0.157758373062327	0.68411331299003	NA	NA	0.531378419208125	0.729035532291591	81.9432890902521
a7922	loss_cnaOV39	1502	Bicalutamide	ANDR (androgen receptor)	9	23	2.30258509299405	NA	4.60787621388814	4.48028122823026	0.127594985657884	0.808631370727168	0.505050727847688	0.212238621816577	0.157791288189998	0.252637960154298	0.684223191001467	NA	NA	0.616262573586368	0.668180739025114	81.9432890902521
a7923	loss_cnaOV102	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.09752230568964	3.91002807094052	0.187494234749122	0.862939779412363	0.72333215618353	0.255627534021113	0.21727383442307	0.2592090413046	0.684324596765316	NA	NA	0.95594047886005	0.747062662362285	81.9432890902521
a7924	NF1_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.11046362362053	1.37388799665989	-0.263424373039363	1.22616949148573	1.37503074516452	0.19363930412421	0.21483520416103	0.191577078524047	0.684336622772124	NA	NA	0.582187559734465	0.712413345073681	81.9432890902521
a7925	gain_cnaOV96	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.57959854201663	4.42829252296099	0.15130601905564	0.581111930801705	0.554555582110581	0.271075429097084	0.260373279286999	0.272841936744707	0.684631445761303	NA	NA	0.366484746557107	0.611493776420827	81.9593636931893
a7926	PTEN_mut	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.7769619864163	3.66780752080347	0.109154465612828	1.15607463302271	1.04991369346881	0.102878090371222	0.0944181824381257	0.103965179511272	0.684671044917551	NA	NA	0.831556249710884	0.867492662289213	81.9593636931893
a7927	loss_cnaOV83	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	2.17382337236485	2.35016896374599	-0.17634559138114	0.876750378649719	1.30864419145306	0.141827933781776	0.201135460759914	0.134754421815248	0.684730005706178	NA	NA	0.392072749731856	0.759205613767652	81.9593636931893
a7928	loss_cnaOV70	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	2.99377349325158	3.25410556347384	-0.260332070222261	1.17691534329171	1.24296475733048	0.210170466529696	0.22119863735835	0.209444450204186	0.685000780952763	NA	NA	0.602176316559396	0.745367962654134	81.9814323255873
a7929	loss_cnaOV38	341	EX-527	SIRT1	8	23	2.99573227355399	NA	5.90301655273841	5.72819905320334	0.174817499535069	0.715701411029036	0.506072199097215	0.310040524677676	0.244260381272291	0.345439840099747	0.68510794109862	NA	NA	0.11188630371365	0.538682521045034	81.9839162770757
a7930	loss_cnaOV21, loss_cnaOV22	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-0.0263700123772862	-0.36318631679965	0.336816304422364	0.69302515911304	1.4518105917736	0.238001171160087	0.486008768936231	0.231997415042202	0.685213100710621	NA	NA	0.889340515209066	0.520735517316681	81.9861602370136
a7931	gain_cnaOV49	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.88242062196109	3.2892720826821	-0.406851460721013	1.6004516607168	1.04293707515477	0.37359384492821	0.254210402417774	0.390101637398054	0.685357913113013	NA	NA	0.0632374989034631	0.705429077227964	81.9931475131163
a7932	PIK3R1_mut	1203	QL-XII-61	BTK	5	18	2.30258509299405	NA	3.2261789605966	4.07638261147034	-0.850203650873745	1.27645960193816	1.51943604158978	0.575924576321325	0.666063892333771	0.559552115128307	0.685506158528324	NA	NA	0.0709448258959119	0.244925707106659	81.9967698243375
a7933	loss_cnaOV87, loss_cnaOV88	272	AR-42	HDAC	3	27	1.63315443905142	NA	0.616566548569679	0.259379022297023	0.357187526272656	1.61792341178557	1.87342652315646	0.192414625016139	0.220769119026751	0.190660013540774	0.685612564797533	NA	NA	0.487667963398427	0.747901672962143	81.9967698243375
a7934	loss_cnaOV1	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.32879056240792	0.970597112304982	0.358193450102937	1.50077149922686	1.56235205115833	0.229858373375061	0.23867287610903	0.229265516589153	0.685761171240398	NA	NA	0.791712812240565	0.726347615918053	81.9967698243375
a7935	ARID1A_mut	1495	AZD-2281	PARP1, PARP2	9	24	2.30258509299405	NA	3.37127431765394	3.6324721132277	-0.261197795573761	0.795667293533488	0.955312901958779	0.284908032782139	0.328275144267656	0.27341596144907	0.685779068899659	NA	NA	0.144200685854547	0.438305887762803	81.9967698243375
a7936	TP53_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	23	10	-1.38629436111989	0.693147180559945	-2.0547547671952	-2.28186433900336	0.227109571808163	1.29373997242337	1.31293746082542	0.174788051943798	0.175544990994406	0.172978209994392	0.685820285438811	NA	NA	0.608743265434716	0.652279919867326	81.9967698243375
a7937	loss_cnaOV38	282	EKB-569	EGFR	8	24	0.916290731874155	2.99573227355399	1.96495393046384	1.58982633575007	0.375127594713771	1.15382910459334	1.57437883727303	0.252283658395442	0.325115385996422	0.238270221774275	0.685950602124603	NA	NA	0.328088672612988	0.480223438011816	82.0020175901038
a7938	loss_cnaOV55	302	PI-103	PI3Ka, PRKDC (DNAPK)	7	25	2.32630161961136	NA	1.12086289728265	1.33722125960175	-0.216358362319095	2.5499240731183	2.29045217842679	0.0922776691572862	0.0848489429940203	0.0944609821400861	0.686320085200055	NA	NA	0.365122177515553	0.843886281496537	82.0107132026725
a7939	loss_cnaOV54	172	Embelin	XIAP	6	13	3.46573590279973	NA	2.93091981222751	3.17508747530441	-0.244167663076895	1.18049063868353	0.855701107963178	0.253635783156568	0.206835746998542	0.285342230838156	0.686327583942135	NA	NA	0.672855874528753	0.662262897535205	82.0107132026725
a7940	loss_cnaOV1	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.45155673640302	1.59652874910402	-0.144972012701	1.04132975206199	1.29281156726868	0.114060794766162	0.139218160639253	0.112137001533241	0.68635769233909	NA	NA	0.165929455791632	0.84183935344948	82.0107132026725
a7941	loss_cnaOV43_(NF1)	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.3708147861725	3.58981791611109	-0.21900312993859	0.983810433888248	0.961261386848333	0.2271113710207	0.222607041351491	0.227828905784544	0.686369075647239	NA	NA	0.729375527806363	0.663869036894245	82.0107132026725
a7942	gain_cnaOV19	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-3.08605574611	-2.695575437043	-0.390480309067	2.20831777535976	1.74474853741034	0.219443159758178	0.176822517766215	0.223803201833644	0.686473833865433	NA	NA	0.697270668965972	0.79163216334422	82.0129024435673
a7943	loss_cnaOV1	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.88521805926711	2.2240506668081	0.661167392459009	1.89123377572613	1.78765158132237	0.36843798406074	0.349595804043398	0.369852492156176	0.686669254155812	NA	NA	0.111699932576698	0.612220424567906	82.0159060297161
a7944	PIK3CA_mut	1243	piperlongumine	Increases ROS levels	7	25	2.30258509299405	NA	1.36471613387701	1.68440649737931	-0.319690363502296	0.746432929573208	0.656813548553648	0.473132392785764	0.428290809309669	0.486729246383967	0.68670491680358	NA	NA	0.210607158886645	0.331766527756997	82.0159060297161
a7945	gain_cnaOV94	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	2.76487372550795	2.3485899681698	0.416283757338153	1.62781897640908	1.4142762760684	0.285226179534109	0.255730989361276	0.294344014944093	0.686849385703943	NA	NA	0.241725311525502	0.554444299699717	82.0159060297161
a7946	loss_cnaOV52, loss_cnaOV53	304	SB52334	ALK5	8	24	2.99573227355399	NA	4.42935375530771	4.34573605005498	0.0836177052527232	1.20200798210956	1.02720180158665	0.0781075294981657	0.0695650166199162	0.0814033864850749	0.687020557148642	NA	NA	0.353476188653679	0.863255666786559	82.0159060297161
a7947	gain_cnaOV96	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.61746833414427	2.90937825369372	-0.291909919549449	0.593579217542811	0.829986176040881	0.36375104558162	0.491779211472133	0.351704556022715	0.687096971817601	NA	NA	0.0198771428497647	0.376308598360531	82.0159060297161
a7948	gain_cnaOV96	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.3613128546063	4.26895241272538	0.092360441880917	0.853035075266692	0.820736118012725	0.11191592500249	0.10827273644292	0.112533663200484	0.687112460001819	NA	NA	0.318591586692633	0.831505049674236	82.0159060297161
a7949	loss_cnaOV40	1032	Afatinib	ERBB2, EGFR	7	24	-0.693147180559945	NA	0.610122421597972	0.283296407160231	0.326826014437741	1.11513003951847	1.80297346140867	0.194091753754046	0.293083320200817	0.181270563007838	0.687322674262293	NA	NA	0.837792235867373	0.567211981917742	82.0159060297161
a7950	loss_cnaOV87, loss_cnaOV88	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	1.23025878432781	0.640896338155308	0.589362446172502	2.33235436341345	2.32229321147573	0.253711255811572	0.252689923717234	0.253784682855782	0.687710900765768	NA	NA	0.946028388894407	0.710821929190658	82.0159060297161
a7951	loss_cnaOV43_(NF1)	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.26693794290731	4.40949691621014	-0.142558973302825	0.917341009546977	1.00313495552346	0.14369060718311	0.155404557104917	0.142113453945422	0.687798226121197	NA	NA	0.512950130876556	0.763981232324816	82.0159060297161
a7952	gain_cnaOV26	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	1.81069604939297	2.06582090240268	-0.255124853009707	1.21555368352938	2.04734434535127	0.12739243395794	0.20988365751889	0.124612576086185	0.687882507537917	NA	NA	0.13375258608991	0.76828487094005	82.0159060297161
a7953	KRAS_mut	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	1.86992332299791	2.39612862354097	-0.526205300543064	0.964358091126698	1.26017147245519	0.428132622155765	0.54565343038526	0.41756642809717	0.687993267178431	NA	NA	0.392126184036645	0.46394944857755	82.0159060297161
a7954	gain_cnaOV26	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	0.107949832906706	-0.0810901602972403	0.189039993203947	0.746505861480904	0.984762463337616	0.194746099528701	0.253233099642289	0.19196506796496	0.688026254358154	NA	NA	0.550335652954754	0.715425694072614	82.0159060297161
a7955	gain_cnaOV4_(KRAS)	134	Etoposide	TOP2	6	13	2.77258872223978	NA	2.6096729959989	2.13268208451467	0.476990911484225	1.19697757644812	2.04739894425737	0.259435565243136	0.398496112934411	0.232974092724874	0.688084380429944	NA	NA	0.411987086167061	0.533496776037687	82.0159060297161
a7956	ARID1A_mut	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	6.83258075720636	6.64944926928827	0.183131487918087	1.43636183019852	1.5614630118915	0.119463741177814	0.127496765834257	0.11728198908551	0.688205747319209	NA	NA	0.339977533155879	0.817316180778885	82.0159060297161
a7957	loss_cnaOV87, loss_cnaOV88	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.37860401725619	3.92581865590629	0.452785361349903	1.8472310309072	1.10241683957536	0.387288123275073	0.245115718485702	0.410720650388752	0.688210685881175	NA	NA	0.0839219027225429	0.714778336936012	82.0159060297161
a7958	BRCA1_mut	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.18861522885858	3.05120019778497	0.137415031073609	0.853967529465405	0.932304042750464	0.148554690634668	0.160913648742163	0.147392937038233	0.688254666843177	NA	NA	0.24043485449637	0.78017325183103	82.0159060297161
a7959	loss_cnaOV56	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.32581334051448	0.970905100776717	0.354908239737759	1.50204556168643	1.56233739407785	0.227740247026109	0.236283271819852	0.227164913982769	0.688280360283667	NA	NA	0.791722649055515	0.728892902908757	82.0159060297161
a7960	RB1_mut	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	1.93303082855449	1.89714269110562	0.0358881374488689	0.226148576912569	1.43679552187414	0.0258028162508954	0.158692740581531	0.0249779017977846	0.688332822336938	NA	NA	0.0348360597059927	0.90354583461548	82.0159060297161
a7961	loss_cnaOV55	1262	UNC1215	LMBL3	8	25	0	NA	2.89758896177577	2.74291630222393	0.154672659551844	0.496793560180948	0.493302388940556	0.313043696130478	0.311341917345924	0.313545328422244	0.688333865568626	NA	NA	0.110868094865606	0.457744686626154	82.0159060297161
a7962	loss_cnaOV56	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-2.6044970308471	-1.92833334542608	-0.676163685421025	3.60200167649134	1.88509259850223	0.331461932199366	0.18771887026984	0.358689905184636	0.688619129820676	NA	NA	0.279920356169051	0.777372630245921	82.0159060297161
a7963	loss_cnaOV38	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-3.91018317598006	-4.27453185489049	0.364348678910428	2.03889648098416	1.03865907557627	0.271790054020958	0.178698959122515	0.350787556261693	0.688621767796507	NA	NA	0.21931138455134	0.640369340496104	82.0159060297161
a7964	loss_cnaOV38	290	KIN001-260	IKK	8	23	2.99573227355399	NA	4.76747972162403	4.87903483843891	-0.111555116814879	1.42210124804828	0.666070069549465	0.122838965118612	0.0784438639428655	0.167482554636235	0.688626524813248	NA	NA	0.666502460694459	0.835942701559139	82.0159060297161
a7965	BRCA1_mut	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.00416994619245	0.821760904105856	0.182409042086596	1.23735772658523	1.36715058504618	0.134605967073136	0.147418194566898	0.133422787571301	0.688854758353629	NA	NA	0.164702645047714	0.798275617073191	82.0159060297161
a7966	loss_cnaOV43_(NF1)	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.90592189655889	6.65858924164943	0.24733265490946	1.3768519600466	1.55190808651817	0.161407250077031	0.179636345871991	0.159373262539259	0.68893208998595	NA	NA	0.339989491724474	0.797703746854236	82.0159060297161
a7967	PIK3CA_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	7	26	0.693147180559945	NA	2.89522249004739	2.77165493439348	0.123567555653905	0.765567496096824	1.0112919382118	0.127572084033543	0.161406481184092	0.122187818358763	0.688952125818414	NA	NA	0.966308898471824	0.730613780647593	82.0159060297161
a7968	gain_cnaOV51_(MYC)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	8	23	2.30258509299405	NA	4.35329597299759	4.56674960535122	-0.213453632353632	0.524446799103972	1.01961168030445	0.230837159519247	0.407007217354214	0.209347966953356	0.688972586096067	NA	NA	0.52992149167489	0.456559889859616	82.0159060297161
a7969	PIK3CA_mut	155	AP-24534	ABL	5	14	-0.669430653942629	NA	1.11288992638059	0.672715452995818	0.440174473384774	0.701000001211334	1.38597916791824	0.349677945143647	0.627923641403921	0.317590973640621	0.689133412688377	NA	NA	0.58657153675028	0.379346394934556	82.0159060297161
a7970	loss_cnaOV102	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.16048362226652	3.89407616371574	0.26640745855078	0.614792037069184	1.26268475624645	0.21676465748712	0.433329390245178	0.210984932884375	0.689202234506348	NA	NA	0.699800427362879	0.565939150086718	82.0159060297161
a7971	loss_cnaOV57_(ZNRF3)	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.3576229657986	1.83734073640131	0.52028222939729	1.29127841907934	1.38897611148188	0.377064238052228	0.402920254617313	0.374579681462059	0.689222607940342	NA	NA	0.0348388262085757	0.495635187429588	82.0159060297161
a7972	gain_cnaOV50	1026	17-AAG	HSP90	4	29	0	NA	-0.62887077916652	-0.517309589893294	-0.111561189273226	2.77255005344242	2.26080859066235	0.0481847376397091	0.0402377548187851	0.0493457030082062	0.689376457842958	NA	NA	0.0621230359655869	0.942723917831479	82.0159060297161
a7973	loss_cnaOV54	222	BX-912	PDPK1 (PDK1)	10	22	2.32630161961136	NA	3.36577074962333	3.42998375703327	-0.0642130074099407	1.02101290630324	1.31080189454147	0.0521612169469454	0.0628914747438753	0.0489875759848541	0.689397303514546	NA	NA	0.328433823261935	0.881827322349495	82.0159060297161
a7974	gain_cnaOV50	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.22900338269761	4.3100413747387	-0.0810379920410842	0.856272956663035	0.80180404745104	0.100343084450282	0.0946403730381674	0.101069572171289	0.689430273195961	NA	NA	0.22676209546179	0.867704797685139	82.0159060297161
a7975	PTEN_mut	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	3.88823311076458	3.79196236867205	0.0962707420925328	0.955833180937522	1.04498401387729	0.0926322782839485	0.100719188256372	0.0921265213764673	0.689623882418388	NA	NA	0.718147169401764	0.881557750577028	82.0159060297161
a7976	PIK3CA_mut	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	2.86952324561012	3.01368097703422	-0.144157731424099	0.44413310183089	0.648325011554644	0.237689305904526	0.324582272363454	0.222354110754447	0.689888513988439	NA	NA	0.850487761617542	0.595832477270272	82.0159060297161
a7977	loss_cnaOV82	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.31541765740178	2.09530160431416	0.220116053087614	0.759966191895363	0.54331432897297	0.393185316709391	0.289639270055741	0.405135740674649	0.689914608989645	NA	NA	0.0429889997303661	0.668928714996542	82.0159060297161
a7978	loss_cnaOV40	306	TG101348	JAK2	7	25	2.32630161961136	NA	3.05809055099031	2.7585296770748	0.299560873915516	1.53917316710409	1.36632337046241	0.213575646709784	0.194624542785611	0.219245956258607	0.690063006932971	NA	NA	0.628667694382264	0.652444548770521	82.0159060297161
a7979	KRAS_mut	303	PIK-93	PI4K, PI3K	7	25	2.99573227355399	NA	3.19734610670742	2.8235564418232	0.373789664884215	1.46567205047987	1.1871556667482	0.299548861864338	0.255029537311457	0.314861542891069	0.690096424405757	NA	NA	0.233218809495204	0.551710451989982	82.0159060297161
a7980	gain_cnaOV50	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.52246329565467	5.86523046476473	-0.34276716911006	0.983004904089092	1.32179333729787	0.265316377558531	0.348693244239395	0.25931978883384	0.690217076951106	NA	NA	0.572319502026254	0.562954253503347	82.0159060297161
a7981	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.66956373182515	4.49474705398512	0.174816677840022	1.68117070162039	0.846159994795061	0.188342428779404	0.10398508472193	0.206600027081595	0.690253716030243	NA	NA	0.529931806736092	0.874558773041637	82.0159060297161
a7982	PIK3R1_mut	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	2.90029070986828	3.39816339741509	-0.497872687546811	1.20375282835911	0.937359686867097	0.511954004797515	0.413600430102816	0.531143694914844	0.69036734251003	NA	NA	0.192610321400511	0.555196463445554	82.0159060297161
a7983	gain_cnaOV26	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.95739223381633	1.71582807698144	0.241564156834899	2.28593839565928	1.66652304897294	0.140997061274237	0.105673957484418	0.144950984616607	0.690429532226181	NA	NA	0.230833101468314	0.873427836151194	82.0159060297161
a7984	gain_cnaOV19	173	FH535	unknown 	3	15	3.46573590279973	NA	2.60106140357815	2.47597938471887	0.125082018859278	1.33350151838839	1.47685909327641	0.0856896626015574	0.0937996823659016	0.0846946194316914	0.690438587996654	NA	NA	0.123534644522495	0.893268819787526	82.0159060297161
a7985	SMARCA4_mut	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.764319563093373	-0.82091174123549	0.0565921781421174	0.664941224096689	0.823173757480796	0.0695876617320153	0.0851085420654989	0.0687487637061093	0.69046712039801	NA	NA	0.0798048569876731	0.90085173819372	82.0159060297161
a7986	loss_cnaOV20	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	3.59332668585323	3.24654531632223	0.346781369531	1.34650390675196	0.881756661200852	0.353887308379418	0.25754204484078	0.393284660938907	0.690517113385967	NA	NA	0.192612520907475	0.652977621008715	82.0159060297161
a7987	gain_cnaOV95_(MECOM)	173	FH535	unknown 	5	13	3.46573590279973	NA	2.85749485587824	2.35810774631741	0.499387109560834	0.924199338594972	1.57622972438979	0.346520045272263	0.540345668630357	0.316823811804566	0.690542637070831	NA	NA	0.123535986675645	0.421862379057769	82.0159060297161
a7988	gain_cnaOV26	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.29708670674913	3.50025955562685	-0.203172848877713	0.145526062638467	0.94058142374748	0.223147963739632	1.39612688747347	0.216007720063435	0.690702271787624	NA	NA	0.794905723967706	0.298334367712456	82.0159060297161
a7989	loss_cnaOV1	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.69146545710741	-4.09112343144234	-0.600342025665073	0.87902753231538	2.43652147941476	0.254423706638183	0.682961572413731	0.246393077482441	0.690763054841659	NA	NA	0.9283180067624	0.415825087347736	82.0159060297161
a7990	loss_cnaOV1	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.79435299569541	4.56713555821582	0.227217437479598	0.811755505586385	0.958893474770047	0.239228203313035	0.279908711324925	0.236957955662476	0.690835098408836	NA	NA	0.94334341102173	0.685313112125233	82.0159060297161
a7991	gain_cnaOV26	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.25255595005641	3.8972247513364	0.355331198720013	0.946462409561274	1.63211617922099	0.226744459945259	0.375430862473159	0.217711951663645	0.690853560741183	NA	NA	0.744668909257101	0.626142865603932	82.0159060297161
a7992	loss_cnaOV52, loss_cnaOV53	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.36942541358045	3.79095158711196	0.578473826468493	1.27315611768248	1.53884995619744	0.38468223512862	0.454362052252858	0.375913079854727	0.690907366632975	NA	NA	0.0709840657405232	0.462490045624053	82.0159060297161
a7993	loss_cnaOV55	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.36942541358045	3.79095158711196	0.578473826468493	1.27315611768248	1.53884995619744	0.38468223512862	0.454362052252858	0.375913079854727	0.690907366632975	NA	NA	0.0709840657405232	0.462490045624053	82.0159060297161
a7994	loss_cnaOV33_(ZFHX3)	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	3.14871661434918	2.73745217156256	0.411264442786619	0.297491238225547	1.29368892925354	0.334116503176626	1.38244220313747	0.317900565960565	0.691434454425925	NA	NA	0.0959118890682916	0.164334298597466	82.0405963554468
a7995	loss_cnaOV56	333	T0901317	LXR	3	29	2.32630161961136	NA	5.17331305336989	4.70990747879259	0.4634055745773	1.37917657621329	1.09932816268568	0.413695159425825	0.336001627760848	0.421535252444722	0.691670241363804	NA	NA	0.00525229801842017	0.623669845953307	82.0405963554468
a7996	loss_cnaOV52, loss_cnaOV53	277	ABT-869	VEGFR and PDGFR family	8	24	0.0237165266173161	NA	2.84034261856708	2.67460028234085	0.165742336226226	0.568823781394338	0.569479716096661	0.291119890977259	0.291377297587572	0.291041685140712	0.691754892243215	NA	NA	0.136953963118474	0.489114203875971	82.0405963554468
a7997	loss_cnaOV58	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.86195310338959	2.86410329642607	-0.00215019303647912	0.845977714630124	0.804241195933109	0.00265478762026865	0.00254166628658678	0.00267356739166338	0.691892091957632	NA	NA	0.0198874055286533	0.995990935969212	82.0405963554468
a7998	gain_cnaOV51_(MYC)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	0	NA	-2.39829977389599	-1.85908373056623	-0.539216043329755	1.67170214466589	2.13038652090431	0.264858341743241	0.322555094548571	0.25310714184432	0.691957446613087	NA	NA	0.279949201625314	0.47069604161026	82.0405963554468
a7999	loss_cnaOV40	263	FR-180204	ERK	7	25	2.99573227355399	NA	4.6965743572906	4.84401868247278	-0.147444325182179	0.702175680588566	0.762446126073839	0.196388398031348	0.209982101713621	0.193383270161569	0.692159092061785	NA	NA	0.766025501021324	0.640051946137933	82.0405963554468
a8000	loss_cnaOV87, loss_cnaOV88	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.95512483711266	1.7160548166518	0.23907002046086	2.14382375263603	1.6795320634013	0.139538767733387	0.111515706534598	0.142343230992988	0.692223104333449	NA	NA	0.230848001807235	0.866836868850182	82.0405963554468
a8001	loss_cnaOV35	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	2.07548554855522	1.59007818457097	0.485407363984254	5.14400233111432	1.64528108813412	0.206949880552867	0.0943637527238643	0.295030051390638	0.692421578632655	NA	NA	0.615636413582178	0.885770962598396	82.0405963554468
a8002	gain_cnaOV94	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.215337891580073	-0.619130750401825	0.403792858821751	0.231687022950949	1.59459951653492	0.269200264244291	1.74283761636162	0.253225248493237	0.692637546999901	NA	NA	0.909785774719168	0.350407280087977	82.0405963554468
a8003	gain_cnaOV51_(MYC)	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	2.37324912353721	2.05569975727617	0.317549366261043	1.91534989487441	1.42786357203248	0.204032798614377	0.165791831096148	0.222394752888772	0.69278770569557	NA	NA	0.94805531066301	0.747056448731904	82.0405963554468
a8004	loss_cnaOV57_(ZNRF3)	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	4.11592459737843	3.89081055782691	0.225114039551521	1.3694619518707	1.21201500645218	0.183132972135975	0.164381375651958	0.185735356701958	0.692794521196059	NA	NA	0.699820484408991	0.772251998219464	82.0405963554468
a8005	NF1_mut	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	0.50564100884537	0.89052351615373	-0.38488250730836	0.564017014729103	1.40877202793598	0.285030742155428	0.682395206629038	0.27320425141622	0.692831285536433	NA	NA	0.16473236767352	0.341532116631916	82.0405963554468
a8006	loss_cnaOV35	1001	AICAR	AAPK1 (AMPK) agonist	5	26	7.60090245954208	NA	8.61091403078189	8.776248740747	-0.16533470996511	1.10316939248058	1.26511839824504	0.132902012450704	0.149872459381184	0.13068714374438	0.692883279113743	NA	NA	0.531449191287673	0.774397972635915	82.0405963554468
a8007	gain_cnaOV4_(KRAS)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	6	13	0.940007258491471	NA	2.57252589689144	2.31891585905356	0.253610037837884	1.26481928224395	0.851038242864042	0.255954230784246	0.200510888312793	0.29800075374333	0.692964675509576	NA	NA	0.413129838449266	0.668264802704426	82.0405963554468
a8008	gain_cnaOV94	1054	PD-0332991	CDK4, CDK6	7	26	1.38629436111989	0.693147180559945	2.72439612986741	2.16563081819125	0.558765311676158	2.27046363499619	1.65371121821173	0.312203477438279	0.246101854732897	0.337885663181501	0.692988236864482	NA	NA	0.111739761517316	0.559793219973615	82.0405963554468
a8009	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.90145119637122	6.65942749793462	0.242023698436594	0.312048321917619	1.62746302079801	0.157929685967785	0.775596859323887	0.148712256649568	0.692992135242393	NA	NA	0.340055709259765	0.593709406424556	82.0405963554468
a8010	loss_cnaOV44	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	2.88838875623471	3.28865468948139	-0.400265933246673	0.911928943753376	1.10081479548956	0.367472024361746	0.438922282255055	0.363608787678643	0.69300171244612	NA	NA	0.0632737227465579	0.535850299376968	82.0405963554468
a8011	loss_cnaOV85	301	PHA-793887	CDK-pan	7	25	2.32630161961136	NA	2.84236955069416	3.05673109191184	-0.214361541217689	0.930283607273581	1.76612377615809	0.131225472122069	0.230426011532039	0.121374019257018	0.693013089243272	NA	NA	0.664589042903844	0.671884743188464	82.0405963554468
a8012	loss_cnaOV44	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.38277931059465	1.19938737869151	0.18339193190314	0.952601102389083	1.26540585419752	0.146996498725992	0.192517026742044	0.144927361679894	0.693153408480141	NA	NA	0.268584383875375	0.780221374544291	82.0405963554468
a8013	gain_cnaOV19	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	2.46839372340198	2.07755381558415	0.390839907817833	2.45736464628175	1.39252536271763	0.251167591251437	0.159048396992776	0.280669866619217	0.693168761904806	NA	NA	0.948055992338303	0.81164115664179	82.0405963554468
a8014	loss_cnaOV42	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	3.14738460285264	2.73764245891921	0.409742143933432	0.297938491243642	1.29374010886602	0.332863751385614	1.37525749769056	0.316711324883152	0.693194849005279	NA	NA	0.0959223757815353	0.166034473373356	82.0405963554468
a8015	loss_cnaOV40	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	2.41693899272452	2.25791825068376	0.159020742040759	1.32010332213713	1.44666569315201	0.111875723975329	0.120460830129053	0.109922245888256	0.693225395557813	NA	NA	0.531452120346589	0.789145537077518	82.0405963554468
a8016	loss_cnaOV1	152	CP466722	ATM	3	29	2.77258872223978	NA	2.49990390547378	2.66212490358627	-0.162220998112499	0.841498014481443	0.817531265223372	0.198035557472802	0.192776447859434	0.198427882838433	0.693243747469457	NA	NA	0.557335635702877	0.775527794525718	82.0405963554468
a8017	PTEN_mut	152	CP466722	ATM	3	29	2.77258872223978	NA	2.65861669802953	2.64570633883913	0.0129103591904074	0.853514784638455	0.818194041695331	0.0157329042360919	0.0151261107865591	0.0157790921621191	0.693402573801359	NA	NA	0.557336801871265	0.981958796411341	82.0405963554468
a8018	loss_cnaOV83	134	Etoposide	TOP2	4	15	2.77258872223978	NA	2.48657276877011	2.22910759997358	0.257465168796527	3.1314676455441	1.43358482489655	0.139160692834022	0.0822186903840074	0.179595350289165	0.693410583427566	NA	NA	0.41207189550735	0.882051178319182	82.0405963554468
a8019	loss_cnaOV84	273	CUDC-101	HDAC, EGFR	6	25	1.63315443905142	NA	-0.202378622930245	0.194982672135914	-0.397361295066159	1.20300758872601	1.70427509504994	0.243945699587895	0.330306557323522	0.233155607460493	0.693431032100977	NA	NA	0.463536221886543	0.520621397732101	82.0405963554468
a8020	loss_cnaOV35	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	2.66194167812187	2.87789525404042	-0.215953575918551	1.42190221857031	1.92584223680203	0.11569801216194	0.151876530677115	0.112134614036275	0.693449916630747	NA	NA	0.348045261755849	0.777655511818497	82.0405963554468
a8021	loss_cnaOV21, loss_cnaOV22	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.89494027104701	2.69752851419228	0.197411756854728	0.424856127150031	0.580081645056024	0.345701112902545	0.464655548641799	0.340317192480141	0.693585638470465	NA	NA	0.136966961350642	0.517361974265425	82.0464230925926
a8022	gain_cnaOV49	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.21719888605746	1.78984741175732	-0.572648525699859	1.207650944077	1.73543854002461	0.335604161863104	0.474183809906703	0.329973382803713	0.69386538606879	NA	NA	0.230861552968093	0.510559862325734	82.0670145270386
a8023	loss_cnaOV83	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.36660707597115	5.15824236665941	0.208364709311746	0.53605796942795	0.804132035911708	0.269283805488558	0.388698090868979	0.259117532950302	0.694041130836435	NA	NA	0.335335156177679	0.486551225795949	82.0670145270386
a8024	gain_cnaOV26	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	2.9498890383931	3.07965331786731	-0.12976427947421	1.59811673912092	0.85978391224231	0.140229672807298	0.0811982480989404	0.150926619615138	0.694056645640886	NA	NA	0.24048353979516	0.901801439304529	82.0670145270386
a8025	loss_cnaOV21, loss_cnaOV22	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	2.81092350489908	2.33593266002554	0.474990844873532	1.48317140679338	1.29731245916358	0.362560954399778	0.320253507246654	0.366134497143252	0.694105681397003	NA	NA	0.111234647175153	0.639842541403112	82.0670145270386
a8026	loss_cnaOV59	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.68165785700635	1.25678211111109	0.424875745895261	1.11334468089557	1.23051540582262	0.348457279094072	0.381621031820526	0.345282752158006	0.694227061846176	NA	NA	0.0986717939074087	0.519005384103476	82.0676777298882
a8027	gain_cnaOV94	221	TAK-715	p38a	7	25	2.99573227355399	2.32630161961136	4.43544350432788	4.23383933565216	0.20160416867572	0.785093198818296	0.925435823073713	0.224223503832829	0.256790109733685	0.217847811430207	0.694284277865834	NA	NA	0.523048854629179	0.575752714358488	82.0676777298882
a8028	PIK3R1_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.33193574647718	4.97546813572601	0.356467610751175	0.682285306663449	1.24623571666367	0.298599813487096	0.522461215667085	0.286035463423792	0.69454530173274	NA	NA	0.802050851792695	0.509433312145293	82.0835779370698
a8029	gain_cnaOV26	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.67136996181087	4.50011187202954	0.171258089781331	0.487759485586769	0.609229940757513	0.284531474445067	0.351111756597228	0.281105832665396	0.694591812768171	NA	NA	0.616331866342585	0.616094585104469	82.0835779370698
a8030	loss_cnaOV57_(ZNRF3)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	1.89607380812946	1.71595599235773	0.180117815771728	1.79413473909608	1.70483606855505	0.105105786178229	0.100392580248725	0.105651105753757	0.695029070691876	NA	NA	0.230871101763913	0.859535670658519	82.125022462787
a8031	gain_cnaOV49	265	Tubastatin A	HDAC6	3	28	2.99573227355399	NA	4.41917434753936	4.79239902689512	-0.373224679355767	0.837939357195076	1.25751517654067	0.30265453233603	0.445407744786092	0.29679536781614	0.695144555367773	NA	NA	0.426599631116743	0.537427151032286	82.1284404952898
a8032	gain_cnaOV18_(CCNE1)	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.71208811560723	3.53324304297974	0.178845072627488	0.934554247209033	0.969275379374933	0.185166770715021	0.191369386166286	0.184514201467515	0.695374587952516	NA	NA	0.729419741591592	0.7396640798073	82.145389351177
a8033	gain_cnaOV96	300	CX-5461	RNA Pol I	4	27	2.32630161961136	NA	3.90441192386563	3.48532371773296	0.419088206132669	1.58109666224731	1.73233001341639	0.244038604960698	0.265061723384448	0.241921690952044	0.695806772894456	NA	NA	0.699615654279146	0.64993075895331	82.1708204477019
a8034	PTEN_mut	262	VX-11e	ERK	3	29	1.63315443905142	NA	3.35228363632523	2.80827696153616	0.544006674789068	1.04262512703916	1.12281436591401	0.486742654025091	0.521766319150524	0.484502773836729	0.695853471542524	NA	NA	0.392487069608384	0.466943100126282	82.1708204477019
a8035	gain_cnaOV50	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.34074206189491	4.41892269678966	-0.078180634894748	0.691551329489267	0.630261967485272	0.122798776015234	0.113051094779164	0.12404466543759	0.695877362948228	NA	NA	0.27285937885037	0.84184236996969	82.1708204477019
a8036	loss_cnaOV43_(NF1)	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.33993942529592	1.52692405435083	-0.186984629054904	0.980159388896838	1.8041983414021	0.108881256771942	0.190769614792298	0.10363862152184	0.695936275773718	NA	NA	0.31785937614018	0.745007404699018	82.1708204477019
a8037	loss_cnaOV36	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.68153892581812	-4.09222637936337	-0.589312546454751	0.664967458452067	2.44201211727939	0.24972106355821	0.886227647630415	0.241322531647097	0.696335859189267	NA	NA	0.928326027508211	0.353041116794135	82.2021663211543
a8038	gain_cnaOV51_(MYC)	1243	piperlongumine	Increases ROS levels	8	24	2.30258509299405	NA	1.60119478896457	1.61890071082938	-0.0177059218648155	0.382128886413114	0.758475244197028	0.0256871121212464	0.0463349474336097	0.0233440998902477	0.696375026750277	NA	NA	0.210688192498917	0.932031718290518	82.2021663211543
a8039	NF1_mut	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	3.55231985232983	3.38957395505878	0.162745897271051	1.19445072176943	1.2340830801977	0.132294667512305	0.136251663048906	0.131875965145702	0.696565132920658	NA	NA	0.32849781269438	0.812212803093269	82.2143788020354
a8040	gain_cnaOV95_(MECOM)	1375	Temozolomide	DNA akylating agent	8	25	3.40119738166216	NA	6.03505720946381	5.9191153127575	0.115941896706312	0.735015867830058	0.69786487883182	0.164124939953292	0.157740671706313	0.166138030760899	0.697050802285852	NA	NA	0.909021149265103	0.701564930962687	82.2552771196902
a8041	NF1_mut	263	FR-180204	ERK	4	28	2.99573227355399	NA	4.68821347686598	4.82941548769249	-0.141202010826505	0.409115468259424	0.780718156234349	0.1878014615911	0.345139750954044	0.180861697270583	0.697104038265702	NA	NA	0.766046409329927	0.593715203459888	82.2552771196902
a8042	PIK3CA_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	0.693147180559945	2.66556270167908	2.86124759504304	-0.195684893363961	1.45389075893049	1.5975220871434	0.124580719067438	0.134593945357978	0.122492762346637	0.697171719817971	NA	NA	0.968922428669843	0.763234105058775	82.2552771196902
a8043	loss_cnaOV57_(ZNRF3)	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	3.0462741759802	3.25590303987768	-0.209628863897481	0.783239874506307	1.27974587411643	0.169180958991061	0.267643247899775	0.163805071098365	0.697727225552326	NA	NA	0.602263171371081	0.665816790229071	82.3105829542007
a8044	loss_cnaOV83	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.216318627198	2.42635091201697	-0.210032284818965	1.36030796394888	0.866209574703298	0.221763193096112	0.154400540455013	0.242472827538194	0.697890837286685	NA	NA	0.735744489491652	0.753728509440122	82.319649217329
a8045	loss_cnaOV34	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.55479033107193	3.22459841413288	0.330191916939054	0.840758886077282	1.07020764184498	0.316719835959032	0.392730808329158	0.30853070378924	0.698143996799374	NA	NA	0.093078014615832	0.467588309102015	82.331375636118
a8046	gain_cnaOV94	1016	Temsirolimus	MTOR	7	24	-1.6094379124341	NA	-1.58936925349142	-2.15768798517434	0.568318731682921	1.35093855378438	1.60345766921875	0.365576714812462	0.420684367983201	0.354433261689922	0.698163794783246	NA	NA	0.0385285730659798	0.368099164328797	82.331375636118
a8047	loss_cnaOV20	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.52056626868029	2.37000875618691	0.150557512493374	1.10948475774903	0.921468212283225	0.158700021524694	0.135700388348581	0.163388720833159	0.698457987845224	NA	NA	0.735747136114472	0.786379280642767	82.3558329015024
a8048	gain_cnaOV18_(CCNE1)	1494	SN-38	TOP1	4	28	-2.99573227355399	NA	-3.83011224483149	-4.23392074806737	0.403808503235883	1.28489190768832	1.3496958106218	0.300596767876586	0.314274298732555	0.299184823763993	0.698758745527954	NA	NA	0.219396559804363	0.590384090143799	82.3610279030964
a8049	loss_cnaOV41	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.563175290634931	-0.852806899308671	0.289631608673741	0.994485815142346	0.782729987844882	0.358803147251704	0.291237546341759	0.370027484792289	0.698762454906532	NA	NA	0.0798505753321651	0.61027473322676	82.3610279030964
a8050	loss_cnaOV42	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.563175290634931	-0.852806899308671	0.289631608673741	0.994485815142346	0.782729987844882	0.358803147251704	0.291237546341759	0.370027484792289	0.698762454906532	NA	NA	0.0798505753321651	0.61027473322676	82.3610279030964
a8051	loss_cnaOV41	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.16099849615801	4.87389811313196	0.287100383026044	1.35648561634972	0.784775111839647	0.333182516675879	0.211650149154274	0.36583777784827	0.699004164402318	NA	NA	0.155765728721683	0.704846014611534	82.3690531130111
a8052	loss_cnaOV42	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.16099849615801	4.87389811313196	0.287100383026044	1.35648561634972	0.784775111839647	0.333182516675879	0.211650149154274	0.36583777784827	0.699004164402318	NA	NA	0.155765728721683	0.704846014611534	82.3690531130111
a8053	TP53_mut	1030	KU-55933	ATM	23	10	2.30258509299405	NA	4.19039447485558	4.06037536556348	0.130019109292101	1.05877879690199	0.979524862931752	0.12545334410061	0.122801013462434	0.132736915837899	0.699289568414646	NA	NA	0.53115568961733	0.73633871766611	82.3924519245657
a8054	loss_cnaOV39	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.21065899008425	3.05774007870723	0.152918911377019	1.24873387508993	0.862720779900776	0.158055117535512	0.122459167984056	0.177251916193101	0.699440717146959	NA	NA	0.672994497542828	0.809492723454456	82.3929876854263
a8055	gain_cnaOV94	1069	EHT 1864	Rac GTPases	7	26	2.30258509299405	NA	4.4450602911178	4.17124174035834	0.273818550759466	0.812959722794158	1.01543681205855	0.279543713234319	0.336816871835109	0.269655922956314	0.699649700355065	NA	NA	0.211185365542339	0.469453585962307	82.3929876854263
a8056	gain_cnaOV95_(MECOM)	288	KIN001-055	JAK3, MNK1	9	23	2.32630161961136	NA	3.68802711479541	3.84518973872281	-0.157162623927397	0.86216453920134	1.09382140628649	0.151537830372882	0.182288434262193	0.143682161479141	0.699706618431535	NA	NA	0.718197766412953	0.673316197676519	82.3929876854263
a8057	gain_cnaOV19	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.24232772267813	3.89914254396983	0.343185178708303	1.04708330240527	1.62434186449373	0.218937629943233	0.327753463282213	0.211276447532347	0.699707924352492	NA	NA	0.744743224475822	0.661450076240287	82.3929876854263
a8058	loss_cnaOV16, loss_cnaOV17	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.49858142007887	5.19772728495579	0.300854135123075	0.894757310194949	0.722949797328984	0.404373110258897	0.336241047371298	0.41614803162628	0.699728297942596	NA	NA	0.128731491764144	0.626967667375176	82.3929876854263
a8059	loss_cnaOV55	1529	MLN4924	NEDD8-activating enzyme	5	12	0	NA	1.58235090496072	1.23160087807405	0.350750026886668	1.79763767157326	1.34640466729788	0.236954083846762	0.195117198773264	0.260508623748754	0.699886826434952	NA	NA	0.857622311195948	0.708111072779789	82.3958414217054
a8060	gain_cnaOV51_(MYC)	1017	Olaparib	PARP1, PARP2	8	23	1.6094379124341	NA	3.99973383695658	3.95916798789096	0.0405658490656204	0.844321158570634	1.26480058503661	0.0344614060004046	0.0480455199468116	0.0320729208584658	0.699965062531913	NA	NA	0.0839887219335836	0.919973358851857	82.3958414217054
a8061	loss_cnaOV38	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	7	16	2.30258509299405	NA	3.9566220939483	3.80851496090386	0.148107133044441	1.16890657683832	0.751026351646661	0.166289771034536	0.126705705981263	0.197206306702433	0.700013051941928	NA	NA	0.940187838144603	0.765323946484645	82.3958414217054
a8062	gain_cnaOV49	306	TG101348	JAK2	3	29	2.32630161961136	NA	2.56854257434459	2.85049131244029	-0.281948738095698	0.678109615750733	1.4438716378671	0.200552798475048	0.415786373687613	0.195272717256358	0.700114190076075	NA	NA	0.628731640295136	0.582589512145683	82.3975242524223
a8063	RB1_mut	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.371268676209612	0.272109614137038	0.0991590620725742	0.999018461474375	1.15723740222001	0.0863989609030981	0.0992564861376364	0.085686015576709	0.700222606599632	NA	NA	0.148222248384617	0.883591813912068	82.4000631644114
a8064	loss_cnaOV38	226	GSK1070916	AURKB	8	24	0.940007258491471	2.32630161961136	2.46287573544832	2.26433459683432	0.198541138613996	1.08370443717136	1.5485616040286	0.136599489270827	0.183205984772213	0.128210035750266	0.700465166282056	NA	NA	0.821600970053704	0.694251966513522	82.4037882023033
a8065	loss_cnaOV56	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.97804903504957	1.51755490430703	0.46049413074254	1.63616423476265	1.21551768966824	0.364997531242278	0.281447376099956	0.37884609550045	0.700483223479272	NA	NA	0.166085449036968	0.67947532454792	82.4037882023033
a8066	loss_cnaOV87, loss_cnaOV88	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.89480868632318	-2.14645256588512	0.251643879561942	0.613043247427648	1.33613147500536	0.193325473324656	0.410483078669978	0.188337663073862	0.700514804945489	NA	NA	0.608838219558432	0.587729242629893	82.4037882023033
a8067	gain_cnaOV4_(KRAS)	303	PIK-93	PI4K, PI3K	8	24	2.99573227355399	NA	3.05333141138063	2.85598677089529	0.197344640485335	1.36302115925428	1.22010198639346	0.157258440276297	0.144784722632849	0.161744380950212	0.700641959404041	NA	NA	0.233308196709132	0.722902839875918	82.4085290086409
a8068	loss_cnaOV20	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.12916187168614	3.33452995531573	-0.205368083629585	0.88244541675308	1.14487333975226	0.184440985442958	0.232726103768807	0.179380614866991	0.701004118960985	NA	NA	0.951109775431847	0.663747274993913	82.4409061853177
a8069	loss_cnaOV54	1239	YK 4-279	RNA helicase A	7	17	2.30258509299405	NA	1.81386217724147	1.46889319945367	0.3449689777878	0.843616458753714	1.12367164525657	0.327079733144137	0.408916841543642	0.307001586490183	0.701165134726609	NA	NA	0.289436485920952	0.423742117170616	82.4438771713391
a8070	loss_cnaOV20	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	6.31803468724123	6.79887032047351	-0.480835633232283	1.19432633562862	1.58255909569523	0.31607638354607	0.402599874831698	0.303834235663123	0.701294800017073	NA	NA	0.340187836866977	0.530369287901491	82.4438771713391
a8071	gain_cnaOV96	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	4	15	0.940007258491471	NA	2.50389947056225	2.37103091111973	0.132868559442519	1.20912470227966	0.945378889212642	0.133267686078532	0.109888218470776	0.140545299835475	0.70138331965511	NA	NA	0.413260417183583	0.848382214664633	82.4438771713391
a8072	loss_cnaOV81_(RB1)	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.23657875956148	5.03706541627864	0.199513343282844	0.488009053443647	0.631796026943441	0.322356014002255	0.408831233508832	0.315787587725214	0.701383755140835	NA	NA	0.111862566848019	0.498525332373595	82.4438771713391
a8073	gain_cnaOV94	287	KIN001-244	PDPK1 (PDK1)	7	25	2.99573227355399	NA	3.40056851218844	3.58463783764335	-0.184069325454903	0.590534774230307	0.971527195594601	0.202673515988113	0.311699384163813	0.189463893846273	0.701463832116791	NA	NA	0.664457832894195	0.54258648393147	82.4438771713391
a8074	gain_cnaOV50	1377	Afatinib (rescreen)	ERBB2, EGFR	4	29	2.30258509299405	NA	2.90570922159232	2.62054449230423	0.285164729288097	0.842982685209517	1.7824726481131	0.1663537036724	0.338280648335288	0.159982667666721	0.701562274418803	NA	NA	0.641250525967967	0.609983442373772	82.4452347463992
a8075	loss_cnaOV52, loss_cnaOV53	1248	FK866	NAMPT	8	24	0	NA	-0.988145137191022	-1.94842861991938	0.960283482728361	2.25711633315531	2.87976561595169	0.349558441663257	0.425447048795196	0.333458902838873	0.701791593181977	NA	NA	0.0453296540478418	0.347692496593755	82.459484945075
a8076	KRAS_mut	262	VX-11e	ERK	7	25	1.63315443905142	NA	2.80242280765374	2.87519692559792	-0.0727741179441885	1.45044322095116	1.03333990748042	0.0644500898508798	0.0501737102790313	0.0704261176959988	0.70186765265851	NA	NA	0.392538593462667	0.904292205279276	82.459484945075
a8077	loss_cnaOV39	300	CX-5461	RNA Pol I	9	22	2.32630161961136	NA	3.40286101546628	3.59525631522982	-0.192395299763541	2.07217199819281	1.56675338801789	0.111788295390445	0.0928471670939157	0.122798713080775	0.701999506027056	NA	NA	0.699649177025157	0.806267166674884	82.459484945075
a8078	loss_cnaOV35	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.29911162711629	3.43043674131051	-0.131325114194225	1.12442133728864	1.24595864468576	0.106729556913974	0.116793509549449	0.105400861219873	0.702075180321386	NA	NA	0.328545773092769	0.821510393104262	82.459484945075
a8079	loss_cnaOV41	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.65237893850635	4.36252426481269	0.28985467369366	1.00206035775642	0.740754665874237	0.375508382912938	0.289258697293079	0.391296453531716	0.702253869771073	NA	NA	0.0438487263722135	0.611519622785659	82.459484945075
a8080	loss_cnaOV42	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.65237893850635	4.36252426481269	0.28985467369366	1.00206035775642	0.740754665874237	0.375508382912938	0.289258697293079	0.391296453531716	0.702253869771073	NA	NA	0.0438487263722135	0.611519622785659	82.459484945075
a8081	ARID1A_mut	1194	SB-505124	TGFR1 (ALK5)	9	23	2.30258509299405	NA	4.67837754859516	4.55324314078211	0.125134407813047	0.700072036519087	1.02650124923093	0.131654040900533	0.178745045203124	0.121903804702429	0.702291881436398	NA	NA	0.943355397838119	0.696591700745369	82.459484945075
a8082	NF1_mut	1030	KU-55933	ATM	4	29	2.30258509299405	NA	3.93139146577385	4.1812848522144	-0.249893386440556	0.151937444067113	1.08769997228013	0.241487123418686	1.64471232206706	0.229744775957572	0.70268844110096	NA	NA	0.531180038427429	0.255776980736576	82.4720473278485
a8083	KRAS_mut	223	ZSTK474	PI3K	7	25	1.63315443905142	2.32630161961136	0.598260952084201	0.803065360286592	-0.204804408202391	0.765040812744118	1.11335756785022	0.194504837160864	0.267703898655786	0.183952051089793	0.702694085955548	NA	NA	0.772766710173066	0.583555036743521	82.4720473278485
a8084	gain_cnaOV26	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.29524471661407	4.4567153030686	-0.161470586454529	2.22937051330693	0.873063543043642	0.158815597764767	0.0724287800034692	0.184947118386843	0.702834571219649	NA	NA	0.376655966628617	0.912001531094828	82.4720473278485
a8085	gain_cnaOV26	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	4.75767731993834	4.95566162193919	-0.197984302000846	1.1703785463799	0.793941911189626	0.240436274970299	0.169162620601028	0.24936875004393	0.702977290172357	NA	NA	0.946174656425044	0.799387710149936	82.4720473278485
a8086	loss_cnaOV87, loss_cnaOV88	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.6416631726188	4.36090058394324	0.28076258867556	0.869501526578566	0.99801035648574	0.283609394012857	0.322900627650814	0.281322319804576	0.70299370793552	NA	NA	0.513068275214547	0.641515990029874	82.4720473278485
a8087	loss_cnaOV1	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-2.44761918549598	-2.28331813344159	-0.164301052054381	2.04476205715265	1.59527469665308	0.100920585572381	0.0803521619934456	0.102992326274019	0.703039736838799	NA	NA	0.125660626318913	0.903650250069303	82.4720473278485
a8088	MLL2_mut	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	0.961953101165593	1.65630287275743	-0.694349771591834	1.1756321871854	1.0254903227368	0.667621143431236	0.590618204537412	0.67709051582152	0.703172447324959	NA	NA	0.289460175508947	0.417004134095249	82.4720473278485
a8089	loss_cnaOV54	1043	JNK Inhibitor VIII	JNK	11	22	2.30258509299405	NA	4.41729313976454	4.45440766838592	-0.0371145286213705	0.857124748841291	1.08582910819798	0.0364695730587108	0.0433011981879464	0.034180819376785	0.703412074923046	NA	NA	0.376660701377116	0.915670157528524	82.4720473278485
a8090	loss_cnaOV35	1021	Axitinib	PDGFR, KIT, VEGFR	5	25	0.693147180559945	NA	2.47783176150531	2.53476911958659	-0.0569373580812802	0.496923110569074	1.1130691328561	0.0543566188974171	0.11457981500614	0.0511534786120436	0.703442247270656	NA	NA	0.197454897338832	0.859000654424384	82.4720473278485
a8091	SMARCA4_mut	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.20508407690269	4.29228838475655	-0.0872043078538649	0.962044202890855	0.81456597208657	0.105627533956306	0.0906448036294215	0.107056163456576	0.703481151110328	NA	NA	0.318741530229208	0.891905353619173	82.4720473278485
a8092	loss_cnaOV1	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.69335341799702	3.46063288450206	0.232720533494963	1.2936082151367	0.877231027175012	0.255775519474171	0.17990032126564	0.26528990230134	0.703511876673697	NA	NA	0.794951478937926	0.78718639481388	82.4720473278485
a8093	loss_cnaOV39	134	Etoposide	TOP2	5	14	2.77258872223978	NA	1.8891030920482	2.42409925817451	-0.534996166126309	3.22842491809432	1.09735727340332	0.291290128278066	0.165714297126076	0.487531434923727	0.703578689010413	NA	NA	0.412228879606176	0.733529555515459	82.4720473278485
a8094	loss_cnaOV44	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.54442847575254	3.27740802498958	0.267020450762963	0.788604624075838	1.13285728774873	0.23986227697361	0.33859863689727	0.235705285785467	0.703643763245653	NA	NA	0.951112105232418	0.632112527160899	82.4720473278485
a8095	loss_cnaOV70	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.1679807362564	2.88566806233695	0.282312673919453	1.17611564234373	0.815802040774504	0.329545846613622	0.24003819331649	0.346055366141805	0.703710152547222	NA	NA	0.332534840165508	0.722353380030317	82.4720473278485
a8096	loss_cnaOV84	235	QL-XII-47	BTK, BMX	6	26	2.32630161961136	NA	1.97437834905647	1.47088358412351	0.503494764932959	0.936046022650512	1.72681309361215	0.310413102943394	0.537895309364449	0.29157455823997	0.703731171222306	NA	NA	0.079906801615575	0.340615990025159	82.4720473278485
a8097	SMAD4_mut	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.19400492204429	4.4379383064283	-0.243933384384009	2.297865108567	0.775185556409686	0.255310210360176	0.106156529151588	0.314677411578461	0.70378958962	NA	NA	0.787246178315667	0.871464183482838	82.4720473278485
a8098	gain_cnaOV94	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.70369641922915	4.55616460962963	0.147531809599512	0.577532410132654	1.02231990156986	0.155269192700139	0.255452000634259	0.144310806600717	0.704111432261065	NA	NA	0.943357251103888	0.627874791445174	82.4995728493329
a8099	loss_cnaOV83	157	JNK-9L	JNK	4	15	1.63315443905142	NA	0.0301218078233847	-0.0479319055829896	0.0780537134063743	1.47741560205501	0.892268619497094	0.0765070794579634	0.0528312502574129	0.0874778196843541	0.70431884603535	NA	NA	0.193435244466162	0.925010153206916	82.5136857877903
a8100	ARID1A_mut	274	PXD101, Belinostat	HDAC	8	22	2.99573227355399	NA	1.00997474901261	0.798320685844581	0.211654063168029	2.09933736386597	2.08978203821541	0.101164609613214	0.100819461803064	0.101280449012172	0.704478149244597	NA	NA	0.417852819839396	0.810842731652004	82.5159193416453
a8101	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	-0.19259599155409	-0.0271837283608489	-0.165412263193241	1.07958255537167	0.940351796226597	0.17056355885568	0.153218725488107	0.175904660210147	0.704626386710013	NA	NA	0.550457451674694	0.721533498089172	82.5159193416453
a8102	loss_cnaOV36	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.14527515785561	2.37881051092593	-0.233535353070328	1.55737511278252	0.800895252832837	0.267819034273217	0.149954465788962	0.291592879648485	0.704648458196508	NA	NA	0.651803616574189	0.820588310678068	82.5159193416453
a8103	gain_cnaOV94	345	KIN001-270	CDK9	7	25	2.99573227355399	NA	5.33883641530013	5.14934897490236	0.189487440397775	0.4327204436923	0.837284543924053	0.24497745010545	0.437898054413431	0.226311881394245	0.704797031794738	NA	NA	0.335428708320365	0.427866397212044	82.5159193416453
a8104	gain_cnaOV26	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.26448548612918	3.06676247462093	0.197723011508248	0.630691320917081	1.00349132101668	0.204445123972057	0.313502033325497	0.197035098727039	0.704833994221012	NA	NA	0.673049421877525	0.676751533564696	82.5159193416453
a8105	SMAD4_mut	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	1.67180367245135	1.9670208131751	-0.29521714072375	1.16143516136897	1.3625509340638	0.218667116464147	0.254183057774642	0.216665031261082	0.704859707369802	NA	NA	0.839655277121938	0.711893745968539	82.5159193416453
a8106	gain_cnaOV95_(MECOM)	1239	YK 4-279	RNA helicase A	6	18	2.30258509299405	NA	1.73714320450666	1.51363113357571	0.223512070930945	1.48013553867678	0.903704267835303	0.21035730424239	0.151007840221689	0.247328776554677	0.704960116987872	NA	NA	0.289481111616893	0.738580266179651	82.5174929495823
a8107	loss_cnaOV56	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.32841908594582	3.5791000140698	-0.250680928123989	1.2665280482166	0.939594281088809	0.259815375216699	0.197927656222831	0.266796992243821	0.705071944869895	NA	NA	0.729465602786157	0.767526754777522	82.5204025431998
a8108	NF1_mut	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	-0.356548926763907	-0.0749775030385557	-0.281571423725352	1.57591099645984	1.22591983194616	0.222301679255104	0.178672161281875	0.22968175926998	0.705191606668934	NA	NA	0.768029802184194	0.751349681299622	82.5242281741418
a8109	loss_cnaOV84	1020	Lenalidomide	TNFA	6	25	1.6094379124341	NA	4.62239426827499	4.34653221177272	0.27586205650227	0.930851955802207	0.732321570568359	0.358164478624653	0.29635438243725	0.376695249176084	0.705335684482078	NA	NA	0.0438599859247233	0.521326210938635	82.5253918572847
a8110	gain_cnaOV94	1022	AZD7762	CHEK1, CHEK2	7	24	0.693147180559945	NA	-0.607294890752441	-0.876142633691949	0.268847742939508	0.874529543811696	0.785965486209755	0.333935511452323	0.307419852012908	0.342060494584821	0.705572257903987	NA	NA	0.0798869972800474	0.48289740162129	82.5253918572847
a8111	gain_cnaOV49	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.855217606998101	1.25214354905116	-0.39692594205306	0.731534004126314	1.27093454514075	0.319273244257811	0.542593973505192	0.312310294476339	0.705711424960657	NA	NA	0.268688440981375	0.464413620870233	82.5253918572847
a8112	loss_cnaOV16, loss_cnaOV17	222	BX-912	PDPK1 (PDK1)	6	26	2.32630161961136	NA	3.6610353434121	3.35196684963433	0.309068493777765	1.21287847788787	1.22754617722154	0.252277384291701	0.254822308592682	0.251777488711112	0.705767336857671	NA	NA	0.328577318616121	0.590805107754625	82.5253918572847
a8113	loss_cnaOV55	1017	Olaparib	PARP1, PARP2	7	24	1.6094379124341	NA	4.26883820621352	3.88236945723542	0.3864687489781	0.957939199219841	1.21366238350072	0.331628299690437	0.403437660023564	0.318431842522266	0.705952623445094	NA	NA	0.0840215790218221	0.395337992419663	82.5253918572847
a8114	loss_cnaOV42	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	3.35480951730699	3.57145312347053	-0.216643606163543	0.925896641036795	0.906648596877945	0.238438887436083	0.233982494980165	0.238949916108135	0.70599950770962	NA	NA	0.664483430516342	0.684139304888763	82.5253918572847
a8115	loss_cnaOV70	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.64335306736671	5.72249276272792	-0.0791396953612074	0.309759920445128	0.491291087039039	0.164420923862645	0.255487201983661	0.161085143714237	0.70609781210225	NA	NA	0.383530138341805	0.718539700260558	82.5253918572847
a8116	loss_cnaOV87, loss_cnaOV88	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.66421291476214	-4.09415149170292	-0.57006142305922	0.644086796001437	2.44291701835751	0.241516740452292	0.885069258674801	0.23335275769723	0.706099762528412	NA	NA	0.928339653890957	0.361523100936684	82.5253918572847
a8117	loss_cnaOV38	225	Genentech Cpd 10	AURKA, AURKB	8	24	2.32630161961136	NA	3.17547281654642	2.73371240488873	0.441760411657696	2.2155994514849	1.73432690052607	0.237785695038176	0.199386405950601	0.254715769860745	0.706132936164545	NA	NA	0.348155224882207	0.618455905222107	82.5253918572847
a8118	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	0.855662660233861	1.25209904372758	-0.396436383493724	0.95633545848872	1.26061222357265	0.31887593576675	0.414536949325507	0.314479247527999	0.706196627907467	NA	NA	0.268692356636592	0.558804953334931	82.5253918572847
a8119	loss_cnaOV35	134	Etoposide	TOP2	3	16	2.77258872223978	NA	2.53425534086994	2.23625869075464	0.2979966501153	3.88994146738505	1.36411840932762	0.16108885751345	0.0766069753526712	0.218453653346841	0.706210589163521	NA	NA	0.412268473036718	0.907159888010251	82.5253918572847
a8120	loss_cnaOV57_(ZNRF3)	269	NSC-207895	MDM4	4	27	2.99573227355399	NA	4.21149759129687	3.83659486004085	0.374902731256015	1.68690342328886	1.58840757132851	0.23447860592204	0.222243150425937	0.236024266078293	0.706331576796048	NA	NA	0.716681569300653	0.698376234900737	82.5253918572847
a8121	gain_cnaOV51_(MYC)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	8	23	-1.6094379124341	NA	0.505233349079884	0.586740173589739	-0.0815068245098551	1.02143575622814	1.27940642426627	0.0666922461001813	0.0797963298355993	0.0637067494456257	0.706371019591771	NA	NA	0.43273630464014	0.858332955200697	82.5253918572847
a8122	loss_cnaOV70	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	2.23516639986313	2.69710426545341	-0.46193786559028	1.07066448326749	1.74696726584224	0.269915143852118	0.431449695781935	0.264422736832206	0.706419214899016	NA	NA	0.641278523799252	0.55147937445536	82.5253918572847
a8123	loss_cnaOV36	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.52126611281597	4.35064472087356	0.170621391942401	0.378192228923831	1.10289892760564	0.159464194112399	0.451149915025791	0.154702654678262	0.706573952250956	NA	NA	0.353647585551322	0.587318712368973	82.5333069056474
a8124	loss_cnaOV102	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.24238798271008	1.90799485004488	0.334393132665195	0.729870862273524	1.38291413378239	0.24783676169488	0.458153832341753	0.241803250466897	0.706751109422757	NA	NA	0.839660605368223	0.537751265045133	82.534124592951
a8125	loss_cnaOV36	309	Y-39983	ROCK	3	29	2.99573227355399	NA	4.78077974643742	4.98327337376762	-0.202493627330202	2.08384223827988	1.16329952369972	0.162513625816993	0.0971732041948398	0.174068348868741	0.706754922977074	NA	NA	0.374411008985334	0.882821078498752	82.534124592951
a8126	loss_cnaOV58	1061	SB590885	BRAF	5	28	1.6094379124341	NA	4.0739061859203	3.90140297395906	0.172503211961248	2.02976235958654	1.14337863171338	0.133477662982775	0.0849869006322425	0.15087146740074	0.706866415298139	NA	NA	0.574563406014418	0.861430770662147	82.5368704189896
a8127	loss_cnaOV57_(ZNRF3)	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	-0.59982471262993	-0.295703472089712	-0.304121240540218	2.04984685925713	1.32912562278442	0.214925391900799	0.1483629077786	0.228813014606631	0.707261149246959	NA	NA	0.88938388416256	0.789892392573805	82.5368704189896
a8128	loss_cnaOV16, loss_cnaOV17	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.68778454381019	-4.03771110259689	0.349926558786696	2.73885259350366	1.68151298140077	0.190409670278215	0.127763925527316	0.208102204774651	0.707417226682332	NA	NA	0.592984196107943	0.848206339876106	82.5368704189896
a8129	loss_cnaOV34	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-3.86653265998179	-4.24213209723346	0.375599437251663	2.68814620700369	0.984674942440098	0.279660964722041	0.139724333547437	0.381445105448605	0.707455969076091	NA	NA	0.219466935243851	0.772312523799781	82.5368704189896
a8130	loss_cnaOV87, loss_cnaOV88	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.40028530654183	2.96944855975964	0.430836746782187	0.783455365951099	1.67515709464934	0.264163221865743	0.549918687785308	0.257191846757735	0.707497882124116	NA	NA	0.664671916972791	0.473817743578094	82.5368704189896
a8131	RB1_mut	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	3.99379662307323	3.61034678766418	0.383449835409056	1.19114224703224	2.08818653539851	0.187902190657241	0.321917752782617	0.183628152422637	0.707512544654347	NA	NA	0.74834823421822	0.65639896209621	82.5368704189896
a8132	gain_cnaOV94	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.58616113172421	-2.77747211696947	0.191310985245257	0.578275055507442	1.30444958158803	0.154125598350078	0.330830429954098	0.146660314009497	0.707550335219092	NA	NA	0.382159371903174	0.694454469640799	82.5368704189896
a8133	gain_cnaOV50	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	3.16536649979435	2.88606019780626	0.279306301988099	0.313098861835448	0.895014414852596	0.325989904225304	0.892070639767738	0.31206905425551	0.707909806063427	NA	NA	0.332586474526592	0.328738975704739	82.5368704189896
a8134	MLL2_mut	1047	Nutlin-3a	MDM2	3	30	2.07944154167984	1.38629436111989	2.63254675612086	3.85921589100831	-1.22666913488745	1.70559165162152	1.51766928804283	0.801487963461786	0.719204467095768	0.808258521505263	0.707954199735048	NA	NA	0.166715307383202	0.338229730943373	82.5368704189896
a8135	loss_cnaOV54	177	GSK-650394	SGK3	6	13	2.77258872223978	NA	4.11272525947907	3.8797624857444	0.232962773734674	0.963341207983277	1.76079226903908	0.148487610385076	0.241827892136343	0.132305654580031	0.708163453219738	NA	NA	0.744811747695658	0.715044561968051	82.5368704189896
a8136	loss_cnaOV81_(RB1)	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	2.58619533423121	2.95091258770026	-0.36471725346905	0.482310899378675	1.3097065426047	0.291348930960335	0.75618704437094	0.27847249868945	0.708182292600402	NA	NA	0.233369831240183	0.31335472553787	82.5368704189896
a8137	loss_cnaOV38	288	KIN001-055	JAK3, MNK1	8	24	2.32630161961136	NA	3.94547406863772	3.75282564477839	0.192648423859325	1.28678457936702	0.946729239064844	0.185934918964793	0.149713034293658	0.203488406093403	0.708207655005905	NA	NA	0.718238856429492	0.705178960178717	82.5368704189896
a8138	loss_cnaOV83	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.12195513731841	2.99161628817989	0.130338849138522	1.59077972039672	0.990391972503876	0.119606957642375	0.0819339393552346	0.131603297236955	0.708267122655371	NA	NA	0.436298087671074	0.867071662050324	82.5368704189896
a8139	gain_cnaOV51_(MYC)	1050	ZM-447439	AURKB	6	16	1.38629436111989	0.693147180559945	2.87054894698698	2.29016758690624	0.580381360080742	1.35880133800066	1.64455621765812	0.367801067852329	0.427127457009069	0.352910623455132	0.708292106385088	NA	NA	0.230140733370593	0.418648288114941	82.5368704189896
a8140	SMAD4_mut	1164	XMD8-92	MAP2K5 (ERK5)	3	20	2.30258509299405	NA	2.81779976188748	2.93819520849229	-0.120395446604802	0.0568680943035407	0.90540062287718	0.13976935585722	2.11710007305988	0.132974777753311	0.708383901926784	NA	NA	0.33259224809561	0.563802778241243	82.5368704189896
a8141	gain_cnaOV94	1149	TW 37	BCL2, BCL2L1	7	26	1.6094379124341	NA	-0.494318519179092	-0.806643084904708	0.312324565725617	0.901215844714029	0.926633310593623	0.338831892285844	0.346559115174814	0.337053030745824	0.708459832129879	NA	NA	0.0426638125027726	0.437894723220277	82.5368704189896
a8142	loss_cnaOV36	1026	17-AAG	HSP90	3	30	0	NA	-0.671191732591712	-0.516796200859883	-0.15439553173183	1.1904232262814	2.37313103645636	0.0666897175694477	0.129698016909603	0.0650598426129805	0.708553709979658	NA	NA	0.0622067630597928	0.858847055116269	82.5368704189896
a8143	gain_cnaOV72_(ASXL1)	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	3.89686998667295	4.11868001434668	-0.221810027673731	1.33107407789864	1.09158654027533	0.196908254119705	0.166639882300091	0.203199672668906	0.708677298853172	NA	NA	0.820321421818199	0.739499597479298	82.5368704189896
a8144	loss_cnaOV36	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.17304173520344	2.74911731225993	0.423924422943506	0.35944580426541	1.27192951771901	0.34401059657236	1.17938342279407	0.333292385338886	0.708700944199585	NA	NA	0.0960116456955038	0.209113733829794	82.5368704189896
a8145	SMARCA4_mut	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	2.61531170208173	3.06731015205043	-0.451998449968707	0.682593606238139	1.22410947857691	0.378345858321586	0.662177972131512	0.369246752744843	0.708719223332841	NA	NA	0.0897824890689183	0.384592002543265	82.5368704189896
a8146	loss_cnaOV52, loss_cnaOV53	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	2.38942179324878	2.06839399964416	0.321027793604618	1.13877069074186	1.42052820389388	0.233966019534333	0.281907320072913	0.225991847768057	0.708805731954641	NA	NA	0.893051275644511	0.655593415099822	82.5368704189896
a8147	loss_cnaOV34	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	3.6963693596988	3.96283602509024	-0.266466665391442	1.12921092575723	1.24254718518424	0.217074264556098	0.23597598935093	0.214451948842435	0.708812215116297	NA	NA	0.699906479097385	0.651359349896971	82.5368704189896
a8148	gain_cnaOV95_(MECOM)	1023	GW 441756	NTRK1	8	23	0.693147180559945	NA	2.44142270159403	2.24874548413529	0.192677217458745	1.59983504372159	1.13700840109512	0.152394288032757	0.120435677549938	0.169459801064941	0.708838171382673	NA	NA	0.845135334289375	0.760130792361179	82.5368704189896
a8149	loss_cnaOV56	1061	SB590885	BRAF	3	30	1.6094379124341	NA	3.60470577925609	3.95982322875623	-0.355117449500136	2.71406507900382	1.12690070159436	0.275358384252933	0.130843380377039	0.315127543179014	0.708947918299879	NA	NA	0.574576930017363	0.842458929153099	82.5368704189896
a8150	KRAS_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	7	25	1.63315443905142	NA	3.11297098843661	2.79399030405582	0.318980684380797	1.00317570422015	0.738383004521752	0.399525748973605	0.317970902842754	0.431998952342355	0.708953138871574	NA	NA	0.0199223976075367	0.455913330076662	82.5368704189896
a8151	loss_cnaOV84	263	FR-180204	ERK	6	26	2.99573227355399	NA	4.69239643639506	4.83931188248013	-0.146915446085068	0.630489312453424	0.772946712364439	0.195604928406517	0.233018138742711	0.190071894653197	0.709109519273656	NA	NA	0.766095468232702	0.634803856524421	82.5383234018541
a8152	loss_cnaOV52, loss_cnaOV53	1053	MK-2206	AKT1, AKT2	8	24	1.38629436111989	0.693147180559945	1.59674491757992	1.21427379993735	0.382471117642565	0.91314477285891	1.29410753017758	0.314547831327673	0.418850470386102	0.295548174107357	0.709172868341386	NA	NA	0.0987588853468205	0.371905945164079	82.5383234018541
a8153	gain_cnaOV95_(MECOM)	206	Ruxolitinib	JAK1, JAK2, TYK2	9	23	1.65632149833295	0.0237165266173161	4.51545812749783	4.42707685576302	0.0883812717348107	0.514889091443228	0.574921350767041	0.157952638330116	0.171651086036954	0.153727586594054	0.709226588254876	NA	NA	0.366699462606544	0.678418448199259	82.5383234018541
a8154	loss_cnaOV16, loss_cnaOV17	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.58780593104182	-2.77716371709742	0.189357786055595	1.81331952260915	1.14362749565514	0.152546575507624	0.104426044993511	0.165576454549231	0.709401268557636	NA	NA	0.382187230958627	0.875620399843942	82.548527407484
a8155	PIK3R1_mut	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	3.54441577365116	3.82675109337228	-0.282335319721124	1.1075165132518	0.969214194466105	0.285891303061738	0.2549265102081	0.291303327306973	0.709496865890303	NA	NA	0.809334416721511	0.711886666334205	82.5485880601191
a8156	loss_cnaOV87, loss_cnaOV88	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.64459307085987	5.72236448650449	-0.0777714156446185	0.637967378206208	0.468155784435322	0.161571396212376	0.12190500376883	0.166122940760893	0.709575790720671	NA	NA	0.383558994468552	0.854449663573115	82.5485880601191
a8157	gain_cnaOV51_(MYC)	1032	Afatinib	ERBB2, EGFR	8	23	-0.693147180559945	NA	0.574561255855214	0.281455681573462	0.293105574281752	2.21775069459208	1.47505802758383	0.173993307715161	0.132163446052111	0.198707826268953	0.709768544136885	NA	NA	0.837860475057652	0.735629386464374	82.5608893346579
a8158	loss_cnaOV35	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.58823400388913	-2.77708345343854	0.18884944954941	1.66297121834365	1.17371354452705	0.152135649321982	0.113561466047204	0.160899097083784	0.709883244020024	NA	NA	0.382194450655991	0.865597477642809	82.5641094520657
a8159	loss_cnaOV57_(ZNRF3)	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	4.02392048430457	3.64958514484385	0.374335339460717	1.5471538342399	1.18846230906757	0.304892220886476	0.241950949657584	0.314974515055853	0.710015993507796	NA	NA	0.199821077571452	0.669103289107201	82.5656845990677
a8160	loss_cnaOV33_(ZFHX3)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	2.2100247647487	2.36237535727644	-0.152350592527733	2.44948427039745	1.43818908657437	0.097355799486399	0.0621970079044489	0.105932240725465	0.710112950983501	NA	NA	0.243901550805165	0.91031167812591	82.5656845990677
a8161	gain_cnaOV49	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.6677862010324	3.34482329951789	0.322962901514515	2.14554928746327	1.64144065228651	0.19226715123434	0.150526908611063	0.196755759073367	0.710416532744282	NA	NA	0.631102148765404	0.821433099086372	82.5656845990677
a8162	gain_cnaOV4_(KRAS)	346	THZ-2-102-1	CDK7	8	24	0.916290731874155	2.99573227355399	-1.28868637079142	-0.98299550140693	-0.305690869384494	2.17172820961716	1.92438442927328	0.15401154635213	0.140759266298052	0.158851248604175	0.710596815285064	NA	NA	0.44535801245904	0.729763419718541	82.5656845990677
a8163	loss_cnaOV34	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-2.35531236758343	-2.28806570435067	-0.0672466632327615	1.2561103983433	1.67671887857126	0.04129203955891	0.0535356313596749	0.0401061049005798	0.710641795337736	NA	NA	0.125708032663134	0.919946729038631	82.5656845990677
a8164	ARID1A_mut	179	5-Fluorouracil	DNA antimetabolite	8	23	3.46573590279973	NA	3.25756411307003	4.12693979042999	-0.869375677359959	1.43596002772076	1.75585239900937	0.516192219975078	0.605431669807607	0.495130272823873	0.710683979584343	NA	NA	0.148871579871156	0.185276555617475	82.5656845990677
a8165	gain_cnaOV72_(ASXL1)	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	1.25273044169737	1.5825937762124	-0.329863334515034	1.20833455174775	2.01903247836851	0.170850905807836	0.272990070537929	0.163376933283204	0.710783636059664	NA	NA	0.783430492988046	0.632257954675211	82.5656845990677
a8166	loss_cnaOV38	172	Embelin	XIAP	4	15	3.46573590279973	NA	3.22786616185945	3.06334609365897	0.164520068200472	1.44122903893152	0.831622022131109	0.170042308900265	0.114152618186519	0.197830340974947	0.710815948169981	NA	NA	0.673108939779463	0.838797939304466	82.5656845990677
a8167	KRAS_mut	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	4.96999618013714	5.2910070331808	-0.321010853043664	0.735508048708068	0.743714328113403	0.432159167348826	0.436447777298325	0.431631933000376	0.710840624259113	NA	NA	0.128853849687479	0.540309574981098	82.5656845990677
a8168	PTEN_mut	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.57404670006168	4.87983924846079	-0.305792548399105	0.972388949176592	0.899512080662672	0.33799444309658	0.314475548758598	0.339953798256747	0.711112292086229	NA	NA	0.666635329885757	0.646634344344586	82.5656845990677
a8169	loss_cnaOV70	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.66689498527672	3.34491549425123	0.321979491025488	0.975898968358255	1.71906222218533	0.191679752304765	0.3299311726573	0.187299497871681	0.711126893080633	NA	NA	0.631106367325814	0.648916363969237	82.5656845990677
a8170	MLL2_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.62264298521579	1.17540101122939	0.447241973986395	1.02936183598277	1.25503448150256	0.360181362256504	0.434484705331431	0.356358315710135	0.711215208532077	NA	NA	0.268732405149564	0.539499688935143	82.5656845990677
a8171	loss_cnaOV52, loss_cnaOV53	1194	SB-505124	TGFR1 (ALK5)	8	24	2.30258509299405	NA	4.69023445793327	4.55450477132828	0.135729686604984	0.651601348227704	1.02407920391574	0.142825703101093	0.208301727696169	0.132538270561494	0.711385523758259	NA	NA	0.943364523654122	0.667449633383029	82.5656845990677
a8172	PTEN_mut	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-5.45578929837497	-4.52898767986247	-0.926801618512506	0.797133712136114	1.44991392117401	0.663609730530101	1.16266769853318	0.639211476611014	0.711448050399256	NA	NA	0.136974679253603	0.101833711017078	82.5656845990677
a8173	loss_cnaOV59	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.0576331200495	2.33414797287651	-0.276514852827009	0.933281761708954	1.29642366742735	0.218812682637568	0.296282284913268	0.213290500454786	0.711574019443716	NA	NA	0.845142918085826	0.623972390208138	82.5656845990677
a8174	TP53_mut	223	ZSTK474	PI3K	22	10	1.63315443905142	2.32630161961136	0.803944414559789	0.657768355143885	0.146176059415904	1.01929253770609	1.13164915747564	0.138653079276376	0.143409329518757	0.12917082865327	0.711588272872409	NA	NA	0.772801499995137	0.731555563537007	82.5656845990677
a8175	loss_cnaOV57_(ZNRF3)	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	1.71752331129954	1.72438027993548	-0.00685696863593832	1.51927157707086	1.62294523591595	0.00425230584704097	0.00451332647791548	0.00422501541283889	0.711594846544547	NA	NA	0.0419984204410844	0.993730638924891	82.5656845990677
a8176	TP53_mut	272	AR-42	HDAC	20	10	1.63315443905142	NA	0.216847791158568	0.45159774245573	-0.234749951297162	1.91609121938476	1.72267999748449	0.126473305681735	0.122515018555608	0.136270202034012	0.711722578901481	NA	NA	0.487890170603673	0.738361709794118	82.5656845990677
a8177	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.719577195716878	-1.24607518236302	0.526497986646146	1.51873062613029	1.31038389436961	0.395378103577897	0.346669763279652	0.401789116081461	0.711738435699435	NA	NA	0.0504710607738248	0.616642287814364	82.5656845990677
a8178	loss_cnaOV35	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.13585202118524	3.33329103874182	-0.197439017556578	0.611118116385505	1.17200619436026	0.177287784707235	0.323078325225151	0.168462435187341	0.711758681464263	NA	NA	0.951119112167918	0.589028469733177	82.5656845990677
a8179	gain_cnaOV50	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	5.04351922603519	4.83385597785685	0.20966324817833	0.730311543575444	0.608091621449909	0.337406651858898	0.287087408137992	0.344788911378877	0.711840713601177	NA	NA	0.0505027778974579	0.615904401981023	82.5656845990677
a8180	gain_cnaOV94	306	TG101348	JAK2	7	25	2.32630161961136	NA	3.0442361344599	2.76240891370331	0.281827220756588	1.25924783828968	1.43701986669323	0.200836306364745	0.223805999253783	0.19611922374122	0.711947631302739	NA	NA	0.628803668541002	0.622409274160047	82.5656845990677
a8181	loss_cnaOV87, loss_cnaOV88	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.69300410330245	3.46781873051831	0.225185372784134	0.655519822086134	1.14829726825765	0.200827597345554	0.343521835949219	0.196103725933108	0.711961486135325	NA	NA	0.72786758978197	0.636582298018692	82.5656845990677
a8182	NF1_mut	230	GSK429286A	ROCK2	4	28	2.99573227355399	2.32630161961136	5.64013675409472	5.52426137658255	0.115875377512167	0.600715283121406	1.02174826020582	0.117311951334608	0.19289567082439	0.113408930580244	0.712022225904419	NA	NA	0.306063433147081	0.756779233960023	82.5656845990677
a8183	gain_cnaOV18_(CCNE1)	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	0.990958020001022	1.22680888349615	-0.235850863495125	2.2565533943044	1.41878418137952	0.147512955510321	0.104518184276259	0.166234489072046	0.712138134503876	NA	NA	0.537396086861546	0.852960771422762	82.5656845990677
a8184	RB1_mut	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	0.894969793509785	1.35281452271057	-0.457844729200782	1.26345139593289	1.21699922735648	0.375236103618198	0.362376210651716	0.376207904581251	0.712224091842599	NA	NA	0.0987760284380284	0.600576567102273	82.5656845990677
a8185	loss_cnaOV40	229	LY317615	PRKCB (PKCbeta)	7	25	2.99573227355399	2.32630161961136	3.06837794171667	2.65959819411249	0.408779747604172	1.83095803472615	1.64624086970728	0.242627302029856	0.223260031006288	0.2483110188346	0.712388397661111	NA	NA	0.323191972713536	0.606805263666567	82.5656845990677
a8186	gain_cnaOV18_(CCNE1)	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.98863293277639	2.84079825222924	0.147834680547157	1.0791192425605	1.1338018805966	0.131006518007894	0.136995685663412	0.130388459462924	0.712455625016714	NA	NA	0.392626302063143	0.811522708055309	82.5656845990677
a8187	loss_cnaOV1	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-4.19758238872691	-4.69689562084306	0.499313232116152	0.758492075655016	1.46225480717494	0.350414287612254	0.658297229651288	0.341468005210951	0.712618020933328	NA	NA	0.136982628981812	0.391294384248559	82.5656845990677
a8188	loss_cnaOV35	1006	Cytarabine	DNA synthesis	5	26	0.693147180559945	NA	-0.273668209074124	-0.0800864324510005	-0.193581776623123	1.34511551337678	1.25550101514049	0.152638347106863	0.14391461156905	0.154186873836547	0.712637312855568	NA	NA	0.768060350687667	0.776905849689712	82.5656845990677
a8189	loss_cnaOV83	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.21632999723775	-3.52054995792672	0.304219960688978	2.52691448381403	1.58513118398674	0.170169167028753	0.120391870258229	0.191920999196949	0.712656499552395	NA	NA	0.683504971792915	0.83105973241401	82.5656845990677
a8190	loss_cnaOV81_(RB1)	263	FR-180204	ERK	4	28	2.99573227355399	NA	4.92785201234854	4.79518141119498	0.132670601153561	0.83793182223108	0.741893914420443	0.176411990014619	0.158331021252196	0.17882691659117	0.712681378544143	NA	NA	0.766109604818451	0.780042366679782	82.5656845990677
a8191	loss_cnaOV38	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	8	24	0.246860077931526	2.32630161961136	0.800200153065535	1.072170279981	-0.271970126915462	1.72938617778005	1.50102342570273	0.174641396838824	0.157263964758051	0.181189795081402	0.712857540944773	NA	NA	0.791813583965714	0.698653613084751	82.5667504300252
a8192	loss_cnaOV56	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.24235434749496	3.42725127960277	-0.184896932107806	1.52049483255559	1.20676712533304	0.150301446846127	0.121603130868283	0.153216745987159	0.712866806706295	NA	NA	0.328636655664976	0.855164259751715	82.5667504300252
a8193	loss_cnaOV54	1013	Nilotinib	ABL	5	16	0.693147180559945	NA	3.47089236820275	3.180078663654	0.290813704548744	1.09181762017722	1.01874456943131	0.281099638583124	0.266357401798974	0.285462826772253	0.712951637286311	NA	NA	0.567966485865673	0.615395417298715	82.5667504300252
a8194	loss_cnaOV21, loss_cnaOV22	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.17611711888832	2.99500221071669	0.181114908171625	1.55116721577981	1.04872968549355	0.166243064537632	0.116760402314572	0.172699324408262	0.713050791600379	NA	NA	0.436336029135774	0.86016672073947	82.5681555759443
a8195	loss_cnaOV58	1009	ATRA	Retinoic acid and retinoid X receptor agonist	5	26	2.30258509299405	NA	4.60455810057338	4.49380070016123	0.110757400412148	1.25283936544253	0.865730970787136	0.119251982393971	0.0884051088010207	0.127935125517626	0.71327707174205	NA	NA	0.530108416076905	0.857745460331415	82.5683052764083
a8196	loss_cnaOV55	225	Genentech Cpd 10	AURKA, AURKB	7	25	2.32630161961136	NA	3.18970168913798	2.7473987370294	0.442302952108584	1.91371595167133	1.84470899920683	0.237961638504839	0.231122571624227	0.23976841458396	0.713441090822359	NA	NA	0.34821606152428	0.598667261693417	82.5683052764083
a8197	gain_cnaOV18_(CCNE1)	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.42923617032008	2.53595104763819	-0.106714877318106	0.926634217367509	1.05588711918379	0.10190652251507	0.115163972275138	0.101066558516783	0.713476021541707	NA	NA	0.197537563075101	0.865583277705829	82.5683052764083
a8198	gain_cnaOV19	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.42923617032008	2.53595104763819	-0.106714877318106	0.926634217367509	1.05588711918379	0.10190652251507	0.115163972275138	0.101066558516783	0.713476021541707	NA	NA	0.197537563075101	0.865583277705829	82.5683052764083
a8199	loss_cnaOV43_(NF1)	281	CH5424802	ALK	5	27	1.63315443905142	NA	4.04252563558083	3.90632417764592	0.136201457934912	0.618728844209209	0.750005278356266	0.185596012826133	0.220131094920893	0.181600665842532	0.713572612747893	NA	NA	0.955964068188397	0.676871917528521	82.5683052764083
a8200	gain_cnaOV49	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.63457412037088	3.95042361034741	-0.315849489976536	1.10976581462738	1.23622540042094	0.257222712961993	0.284609136282133	0.25549506576146	0.713574211871546	NA	NA	0.699930979189685	0.679695484778422	82.5683052764083
a8201	loss_cnaOV39	1052	RO-3306	CDK1	10	23	1.6094379124341	NA	3.41282925167229	3.51177192488391	-0.0989426732116132	0.890578433841481	0.919600800665947	0.108576661055778	0.111099336624206	0.107593069884195	0.713768777038904	NA	NA	0.794986437393437	0.774878114791212	82.5717878339187
a8202	loss_cnaOV83	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	3.4619932208348	3.18668206356748	0.275311157267321	0.860524673109519	1.28499714705221	0.222591227301497	0.319934065658432	0.214250403511701	0.713778358762905	NA	NA	0.602366555156365	0.564396685149661	82.5717878339187
a8203	loss_cnaOV38	306	TG101348	JAK2	8	24	2.32630161961136	NA	3.02797841830657	2.75608535155623	0.271893066750335	1.4991157161114	1.37262412309066	0.193772082857022	0.181368965603007	0.198082681322931	0.713900542843097	NA	NA	0.628815222263997	0.65884168572444	82.5758546441819
a8204	loss_cnaOV16, loss_cnaOV17	269	NSC-207895	MDM4	6	25	2.99573227355399	NA	4.14268857411149	3.82311680566486	0.319571768446626	1.69128035045773	1.57888797761264	0.199878548366104	0.188952569785451	0.202403066574637	0.714017630084217	NA	NA	0.716719284344959	0.686029690355769	82.5793309907994
a8205	NF1_mut	1192	GSK269962A	ROCK1, ROCK2	4	28	1.6094379124341	NA	2.10946459613792	2.48682167493746	-0.377357078799542	2.12672503635324	1.37144751967738	0.257650516199747	0.177435762662863	0.275152401667043	0.714184232695058	NA	NA	0.241954176104429	0.750700581649775	82.5885324659654
a8206	loss_cnaOV58	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.83929383249529	1.71966249458627	0.119631337909014	1.55894497166789	1.7360010794626	0.0697891260369103	0.0767386534375375	0.0689120181572973	0.714424256831379	NA	NA	0.231023840393213	0.881769652493347	82.6062211565785
a8207	gain_cnaOV95_(MECOM)	292	Masitinib	KIT	9	23	2.99573227355399	NA	4.13326910082609	3.96666224107331	0.166606859752777	1.14743880674139	1.02068331090862	0.157775600206253	0.145198906271894	0.16323070826392	0.714723467821686	NA	NA	0.106020374607644	0.709501361327435	82.6220120993047
a8208	PTEN_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	0.623902209707474	0.904302713518818	-0.280400503811344	0.503234184111129	1.31003573325863	0.223791182614721	0.557196853203882	0.214040347673469	0.714734981328898	NA	NA	0.845504022007845	0.444533264083692	82.6220120993047
a8209	loss_cnaOV33_(ZFHX3)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.850976934088946	0.523443816623974	0.327533117464972	1.60858630393777	1.16384201218409	0.269041375012406	0.203615508016686	0.281424036970719	0.714925971638642	NA	NA	0.432806801185587	0.717646859107504	82.6221056790875
a8210	loss_cnaOV40	1170	CCT018159	HSP90	8	25	2.30258509299405	NA	3.94648053425119	3.61447227454722	0.332008259703972	1.49367557014086	1.13535039463948	0.270926460576678	0.222276019197839	0.292428012771684	0.714986062852405	NA	NA	0.199857502055534	0.576677683096429	82.6221056790875
a8211	gain_cnaOV95_(MECOM)	221	TAK-715	p38a	9	23	2.99573227355399	2.32630161961136	4.18750863182659	4.31332653196347	-0.125817900136874	0.838117053448746	0.923258396654942	0.139589715174921	0.1501197232763	0.136275933793535	0.714997024697521	NA	NA	0.523201909984765	0.715596519019835	82.6221056790875
a8212	loss_cnaOV35	1022	AZD7762	CHEK1, CHEK2	5	26	0.693147180559945	NA	-0.8191722209069	-0.814716397666898	-0.0044558232400016	0.78304007036531	0.818190382633467	0.00547780416047134	0.0056904153550186	0.0054459491758628	0.715665337668166	NA	NA	0.0799391681907258	0.991157199661501	82.6892626209793
a8213	gain_cnaOV18_(CCNE1)	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	3.57872595251508	3.2504388452124	0.328287107302679	0.330163534895942	1.07026524571648	0.334610247342127	0.994316672209564	0.306734343300953	0.715898848209225	NA	NA	0.192966915865505	0.322816187083613	82.7061714697721
a8214	loss_cnaOV54	140	Vinorelbine	Microtubules	6	13	-2.74887219562247	NA	-3.73868721621903	-3.32626508157982	-0.412422134639205	0.362924583606813	2.10689901139782	0.231560185915035	1.13638522510786	0.195748411484414	0.716202713754093	NA	NA	0.683538356159217	0.50550125459213	82.7312031661025
a8215	gain_cnaOV51_(MYC)	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-3.00820288822107	-2.65407305896991	-0.354129829251153	0.582878397020499	1.37180620660869	0.287331372900476	0.607553532711727	0.258148583630202	0.716653271510394	NA	NA	0.382294355586644	0.442594660588067	82.7355105282448
a8216	loss_cnaOV43_(NF1)	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.724024949772258	-1.24540801925472	0.521383069482459	1.52535908830294	1.30985414910147	0.391463526979669	0.341810052125189	0.398046660263754	0.71669042128982	NA	NA	0.0504971476686308	0.621236200485285	82.7355105282448
a8217	loss_cnaOV44	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.724024949772258	-1.24540801925472	0.521383069482459	1.52535908830294	1.30985414910147	0.391463526979669	0.341810052125189	0.398046660263754	0.71669042128982	NA	NA	0.0504971476686308	0.621236200485285	82.7355105282448
a8218	gain_cnaOV51_(MYC)	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	3.07196756562074	2.94137943417329	0.130588131447448	0.597587797967516	0.610077974432826	0.215079472912342	0.218525431562688	0.214051542458736	0.716769835978659	NA	NA	0.850619013303546	0.688699163699396	82.7355105282448
a8219	loss_cnaOV70	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	4.10479244914099	3.59886446082958	0.505927988311411	1.42638013942365	2.07508185387352	0.248214616096201	0.354693657271363	0.243811099483619	0.716819458399661	NA	NA	0.748387455431518	0.617183558697548	82.7355105282448
a8220	SMARCA4_mut	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-1.742928161419	-1.09257253750771	-0.650355623911291	0.411848401126759	1.38637373980881	0.490902850948397	1.57911411609711	0.46910555590946	0.7168338729514	NA	NA	0.0504978955204582	0.123740708044398	82.7355105282448
a8221	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.69440824915519	4.86694336820077	-0.172535119045579	1.43256334010768	0.856470263157493	0.19001412824836	0.120438038734546	0.201449047874125	0.716850384796161	NA	NA	0.666667325899364	0.8555087666084	82.7355105282448
a8222	loss_cnaOV85	200	LAQ824	HDAC	6	13	0.0237165266173161	NA	-2.98615722450857	-2.63700722458713	-0.34914999992144	1.27722139708835	1.21202894884293	0.283501883973579	0.273366857709548	0.288070677069849	0.717127617493998	NA	NA	0.382301250587105	0.586820269650302	82.7446397135983
a8223	gain_cnaOV51_(MYC)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.6094379124341	NA	1.30786482823917	1.1230767795489	0.184788048690263	1.02100537796659	1.61635711913916	0.122972015097476	0.180986361754805	0.114323775669499	0.71714010665077	NA	NA	0.813791231981426	0.707149752278618	82.7446397135983
a8224	loss_cnaOV82	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.59831846859421	4.43679087669818	0.161527591896025	0.917622137598844	0.524001752196274	0.288991880363459	0.176028438370827	0.308257732381631	0.717196319627068	NA	NA	0.36676456510756	0.790949869362753	82.7446397135983
a8225	loss_cnaOV42	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-1.80981684227548	-2.01462841676627	0.204811574490788	1.80657292443532	2.07287596112152	0.099975474312983	0.113370222547095	0.0988055138523463	0.71729782367569	NA	NA	0.280155998907993	0.844554612353611	82.7446397135983
a8226	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.28002757505033	3.96416724358775	0.315860331462585	0.730536724290607	1.09327193356392	0.30020249592546	0.432367492228818	0.288912869493431	0.717365518807517	NA	NA	0.106035444441245	0.440419070115629	82.7446397135983
a8227	loss_cnaOV52, loss_cnaOV53	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	1.6094379124341	NA	1.29411134368558	1.12053483422774	0.173576509457844	2.00338732221808	1.2836948770122	0.115502967078302	0.0866415133673034	0.135216329492444	0.71757339883867	NA	NA	0.813792531110602	0.813439889047249	82.7557591016504
a8228	gain_cnaOV51_(MYC)	203	BMS-345541	IKBKB	8	24	2.77258872223978	NA	3.28316290265107	3.27386690065579	0.00929600199527947	0.811737206975118	1.1122533568157	0.00885455417579424	0.0114519846021601	0.00835780979065167	0.717636357419532	NA	NA	0.0931853587506495	0.98003746753134	82.7557591016504
a8229	gain_cnaOV50	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.13909854541101	2.99382218877875	0.145276356632257	1.00841424146746	1.09835240469996	0.133318649886118	0.144064165953119	0.132267527262293	0.718032157521624	NA	NA	0.436374746827267	0.802799612534962	82.784893155099
a8230	loss_cnaOV41	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.07336085860656	2.35852710794731	-0.285166249340747	0.889396890248909	1.52044064247575	0.196364102234118	0.320628790663907	0.187555003052541	0.718063901493745	NA	NA	0.821655163919214	0.577615823871854	82.784893155099
a8231	SMARCA4_mut	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	3.94078942247007	4.34460070752569	-0.403811285055621	1.19376132382302	1.32313537530303	0.307040485627995	0.33826802476932	0.305192720709428	0.718231962943035	NA	NA	0.372941649880116	0.625532479736248	82.784893155099
a8232	loss_cnaOV52, loss_cnaOV53	1023	GW 441756	NTRK1	8	23	0.693147180559945	NA	2.41637333427037	2.25745830755221	0.158915026718158	1.53913018063981	1.1647404856655	0.125595333947919	0.103249893165046	0.136438141091454	0.718237998387471	NA	NA	0.845161033927442	0.795165701578662	82.784893155099
a8233	KRAS_mut	330	XMD13-2	RIPK	7	25	2.32630161961136	NA	3.92682145684012	4.12803840491378	-0.201216948073655	1.172442412451	1.11441384257248	0.178659606318664	0.171622031015586	0.180558550501465	0.718339782261298	NA	NA	0.820350862336741	0.694201831165893	82.7865681977591
a8234	loss_cnaOV54	329	QL-XI-92	DDR1	10	22	2.32630161961136	NA	4.53040001582977	4.53516279475411	-0.00476277892434496	0.970293334707666	1.04835119791209	0.00464408605411918	0.00490859697163632	0.00454311392387454	0.718573617389559	NA	NA	0.193106524367582	0.99012166808253	82.7940578879683
a8235	loss_cnaOV40	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	4	15	2.07944154167984	NA	3.67573166144366	3.40795982441131	0.267771837032355	0.867496545086562	1.16777063645513	0.238944851393716	0.308671934832473	0.229301738434869	0.718579288715059	NA	NA	0.774646102346429	0.629513824774891	82.7940578879683
a8236	loss_cnaOV40	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	2.38806671876899	2.07291835629843	0.315148362470561	0.969724132243195	1.65648860017238	0.202347965079292	0.324987645446701	0.190250848957105	0.71876640833377	NA	NA	0.948099445672532	0.638423849774608	82.805562321501
a8237	PTEN_mut	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	3.74805356788245	3.85424821646266	-0.106194648580205	0.686259625645668	0.888474310832634	0.121928348929113	0.154744129789498	0.119524726022394	0.719159590559821	NA	NA	0.924043619641239	0.792606024458597	82.8336089835336
a8238	gain_cnaOV18_(CCNE1)	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.882742851081104	0.778847597684417	0.103895253396688	0.341065047491533	1.20249507100846	0.0956408777721329	0.304620054622475	0.0863997332725508	0.719184459859203	NA	NA	0.359270239525546	0.785288550839916	82.8336089835336
a8239	loss_cnaOV39	271	VNLG/124	HDAC, RAR 	9	22	1.63315443905142	NA	4.43451523153739	4.28633451272478	0.148180718812615	0.756990287255352	0.509518997391856	0.251888721640205	0.195749828376107	0.290824718157964	0.719293082830601	NA	NA	0.255986898050935	0.600275659215219	82.8348567969131
a8240	PTEN_mut	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.3649852634389	4.38952243661702	-0.0245371731781221	1.80083355197722	0.908834209864977	0.0246968055181251	0.0136254531415086	0.0269985140433562	0.719442539014917	NA	NA	0.513188204366631	0.983434616302855	82.8348567969131
a8241	loss_cnaOV84	224	AS605240	PI3Kgamma	6	26	2.99573227355399	2.32630161961136	3.09675618248397	3.4393345074697	-0.342578324985726	1.685112561409	1.67524755361091	0.204293155744598	0.203296997975779	0.204494150280844	0.719457200238729	NA	NA	0.631154919019449	0.665933345555298	82.8348567969131
a8242	loss_cnaOV54	156	AZD6482	PI3Kbeta	6	13	1.63315443905142	NA	1.93848998140331	2.23193094854866	-0.293440967145348	0.77590152792142	1.78387416650323	0.188501372435342	0.378193567850619	0.164496449724677	0.719761049122952	NA	NA	0.948101042757297	0.623831346065515	82.8497666502188
a8243	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	310	YM201636	FYV1	7	25	1.63315443905142	NA	2.25378900520968	2.38579229015805	-0.132003284948365	0.893759924880701	0.867734321050758	0.151206249861778	0.147694343048537	0.152124079624417	0.719880839011359	NA	NA	0.651889289866884	0.735797288013606	82.8497666502188
a8244	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	5.0281126703918	4.82894373822865	0.199168932163148	0.46492312218676	0.641689238257447	0.320705231828457	0.428391109537335	0.310382222871628	0.72001220911192	NA	NA	0.050532927616859	0.436660003419144	82.8497666502188
a8245	loss_cnaOV36	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-2.74836622198849	-3.37591895354374	0.627552731555253	2.25771806304553	1.79233061847913	0.343256314627251	0.277958856700079	0.350132238486089	0.720122009647243	NA	NA	0.141074588747224	0.682046135291986	82.8497666502188
a8246	loss_cnaOV85	262	VX-11e	ERK	7	25	1.63315443905142	NA	2.65965931900254	2.91517070242026	-0.255511383417721	1.15032157464719	1.11770220642414	0.227262275040479	0.222121699748253	0.228604168399361	0.720182952599495	NA	NA	0.39268793590365	0.613281556702411	82.8497666502188
a8247	loss_cnaOV21, loss_cnaOV22	152	CP466722	ATM	3	29	2.77258872223978	NA	2.51639737830212	2.6604186822592	-0.144021303957082	0.86852290129492	0.815841657938194	0.17575166542903	0.165823265848666	0.176530951264556	0.720198989064952	NA	NA	0.557523179350895	0.805434727259156	82.8497666502188
a8248	loss_cnaOV55	238	CAL-101	PI3Kdelta	7	25	2.99573227355399	2.32630161961136	4.54994398077467	4.3416599434715	0.208284037303168	1.10232992922494	0.959319093914818	0.210478050509617	0.188948908834958	0.217116534659179	0.720268293096425	NA	NA	0.513194011326452	0.660866761508775	82.8497666502188
a8249	loss_cnaOV54	1133	JNJ-26854165	MDM2	11	22	2.30258509299405	NA	3.22662173388902	2.98847398083724	0.238147753051781	0.618282479245791	1.03170832769943	0.259166609655163	0.385176292464707	0.230828565262061	0.720285241967258	NA	NA	0.240689981313532	0.415404218816567	82.8497666502188
a8250	loss_cnaOV41	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.54912258158609	4.38322929073184	0.165893290854252	0.741476780149787	0.61600707806997	0.261590263508457	0.223733629016326	0.269304195942062	0.720579645600641	NA	NA	0.273064171884591	0.657136586816664	82.8735835011094
a8251	gain_cnaOV96	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.59726877794394	2.49481033594614	0.102458441997797	0.615071091627452	0.636218558400439	0.161749324744445	0.166579836692854	0.161042837630192	0.720729059542628	NA	NA	0.858679346837807	0.745807878111188	82.8798714531926
a8252	ARID1A_mut	170	Shikonin	unknown	5	13	2.77258872223978	NA	0.179933053265146	-0.0848249141198147	0.264757967384961	0.527675077300045	0.863550469685466	0.33385532489025	0.501744309660498	0.306592349467883	0.720809018105216	NA	NA	0.587148589090183	0.446086616112557	82.8798714531926
a8253	loss_cnaOV40	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.916471576017831	0.779041103297739	0.137430472720093	0.164606133889964	1.16464170069871	0.126560545794073	0.834904930164767	0.118002362990818	0.721059743820327	NA	NA	0.359301208630656	0.678929366762875	82.8986544445226
a8254	gain_cnaOV49	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.69734239532037	4.86662899539735	-0.16928660007698	1.12684975015384	0.889725696551912	0.186424782131828	0.150229966376501	0.190268304864119	0.721196769500129	NA	NA	0.666691055247791	0.822060246102429	82.9043626250654
a8255	gain_cnaOV51_(MYC)	260	NG-25	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	2.83635966802754	3.0705224218012	-0.234162753773663	0.874645528369285	1.14232306165686	0.215662457429303	0.267723033135769	0.204988204855136	0.721373833722981	NA	NA	0.436400270950386	0.554085345030084	82.9146714507298
a8256	KRAS_mut	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.45535267566109	4.49944593646541	-0.0440932608043205	0.589085171090464	0.704219684401036	0.0646533174861547	0.0748504001937425	0.0626129342604551	0.721490404140744	NA	NA	0.0543731498908292	0.870746247392086	82.9180254664409
a8257	ARID1A_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	6	17	2.30258509299405	NA	1.47847526577037	1.5930205512689	-0.114545285498526	0.666268383530769	1.18390967632981	0.105734091654236	0.171920637883962	0.0967517098547775	0.721735530477377	NA	NA	0.456768204456581	0.775811935245938	82.9227837720986
a8258	gain_cnaOV51_(MYC)	151	QS11	ARFGAP	5	14	2.32630161961136	NA	3.79241677873545	3.75762329688684	0.0347934818486073	1.20925222587985	1.55180280596035	0.023535176794687	0.0287727250808172	0.0224213293821666	0.721784598094604	NA	NA	0.0664498007152868	0.960384188333675	82.9227837720986
a8259	MLL2_mut	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	0.237554332811766	0.904502766846811	-0.666948434035045	0.810516281676484	1.37110480460969	0.496972437512745	0.822868644483635	0.486431403195984	0.721989798158197	NA	NA	0.164936392035127	0.290675346673112	82.9227837720986
a8260	gain_cnaOV18_(CCNE1)	1248	FK866	NAMPT	4	28	0	NA	-0.853597577595206	-1.83046634518616	0.976868767590957	2.19949405343849	2.81583984526306	0.353886023938335	0.444133397889305	0.346919150687597	0.722006624393018	NA	NA	0.0454003480252909	0.463699394845724	82.9227837720986
a8261	BRCA1_mut	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.01879997964775	1.35147609359088	-0.33267611394313	1.16613457767319	1.22876030589281	0.272096074602138	0.285281064735191	0.270741260396924	0.722136536455561	NA	NA	0.0988302553530366	0.624016818356101	82.9227837720986
a8262	PIK3CA_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	0	NA	-1.7276395655356	-2.06038517294517	0.332745607409572	1.17901599389193	2.20270992312827	0.16271431598709	0.282223149756585	0.151061927817081	0.722230805460379	NA	NA	0.280193809414632	0.598212020007899	82.9227837720986
a8263	KRAS_mut	1072	BMS-708163	g-secretase	7	26	1.6094379124341	NA	3.74252112693144	3.86799094847795	-0.125469821546515	0.939190037324824	0.852667163163155	0.144204051581008	0.133593646184644	0.147149822307051	0.722258452169149	NA	NA	0.924047417935574	0.756571417537962	82.9227837720986
a8264	ARID1A_mut	167	OSU-03012	PDPK1 (PDK1)	5	14	2.77258872223978	NA	2.21323912748152	2.34868802201726	-0.135448894535738	0.814185084278632	1.3490962905857	0.108872917445621	0.166361306723944	0.100399723489665	0.722365274198219	NA	NA	0.39264842980536	0.795973404475551	82.9227837720986
a8265	NF1_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	2.12093874820876	1.68494013855369	0.435998609655067	0.985047065884239	1.76850099828141	0.25520015369752	0.442617032987848	0.246535687612708	0.722368315153463	NA	NA	0.231082970036109	0.48862759478655	82.9227837720986
a8266	loss_cnaOV42	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.270661480936158	-0.0337542580769721	-0.236907222859185	1.4260290769838	0.904060474779301	0.244487899360441	0.16613070987323	0.262047981820043	0.722576657834044	NA	NA	0.550580198965317	0.765727421717223	82.9227837720986
a8267	loss_cnaOV54	205	BMS-708163	g-secretase	10	22	2.32630161961136	0.940007258491471	5.1831335993088	5.00694594095271	0.176187658356087	0.632294028112206	0.610218147250125	0.285590603618452	0.278648303673083	0.288728972007888	0.722809296863359	NA	NA	0.111990291744321	0.470274735032608	82.9227837720986
a8268	loss_cnaOV38	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.2373045011885	5.24424313123319	-0.00693863004469719	0.863671168197624	0.72831105093451	0.00921999022394903	0.00803387944416075	0.00952701463995926	0.722954343796378	NA	NA	0.128981061019265	0.988874248473646	82.9227837720986
a8269	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.74031187736702	3.04008551156372	-0.299773634196703	1.70185364968146	1.02921332959903	0.275759771177269	0.176145366114656	0.291264819037557	0.722962641677937	NA	NA	0.436412280736544	0.791025775061212	82.9227837720986
a8270	loss_cnaOV39	341	EX-527	SIRT1	9	22	2.99573227355399	NA	5.88975596768787	5.72567758801788	0.164078379669987	0.663204229050849	0.52147793600122	0.290845679338695	0.247402493052267	0.314641077488661	0.723039961573577	NA	NA	0.112128257330921	0.519555878307815	82.9227837720986
a8271	loss_cnaOV55	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	1.51396265849977	1.08734097989648	0.426621678603291	0.398084536494228	1.74402796159072	0.268064328086646	1.07168613571474	0.244618600159467	0.723051415550738	NA	NA	0.537532954730554	0.398280213968151	82.9227837720986
a8272	gain_cnaOV50	283	GSK2126458	PI3K, MTOR	4	28	-2.05572501506252	0.0237165266173161	-2.98382369027474	-2.69623429112421	-0.287589399150523	1.35236950645052	1.82196290193908	0.161513962694493	0.212655932996701	0.157845913791355	0.723057294682274	NA	NA	0.697458634166841	0.721123774444815	82.9227837720986
a8273	loss_cnaOV1	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-3.86613488057591	-3.67242144437743	-0.193713436198476	1.70983811082297	1.74498318428872	0.111164593884097	0.11329343694722	0.111011634921534	0.7231016308761	NA	NA	0.247159690854686	0.866557457617689	82.9227837720986
a8274	loss_cnaOV42	219	AT-7519	CDK9	4	28	2.32630161961136	NA	1.33016316360437	1.52164264069766	-0.191479477093289	1.14685725421636	1.7695950981819	0.111486528535086	0.166960165608513	0.1082052483588	0.723104914482226	NA	NA	0.318086263062192	0.783906888375151	82.9227837720986
a8275	loss_cnaOV52, loss_cnaOV53	173	FH535	unknown 	4	14	3.46573590279973	NA	2.52513683766632	2.48873768791802	0.0363991497483021	0.47594433821526	1.60402029463358	0.0249230979995366	0.076477745033789	0.0226924496342591	0.723222946676456	NA	NA	0.123931154270995	0.941756331171415	82.9262967168355
a8276	loss_cnaOV70	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.09423223060746	2.11742014699359	-0.0231879163861337	0.378052756334826	0.574169436014668	0.0411439690557482	0.0613351337811624	0.040385145797871	0.723420570373948	NA	NA	0.0431009852641668	0.929713242634771	82.9375311078844
a8277	loss_cnaOV70	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.15387088535909	2.2971853841989	-0.143314498839812	2.27392432504906	1.76775236775567	0.0794119059777848	0.0630251839347028	0.0810715920701967	0.723637358840042	NA	NA	0.111919261860551	0.924290882672951	82.9375311078844
a8278	loss_cnaOV33_(ZFHX3)	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	-0.292591699381972	-0.0844526478358795	-0.208139051546092	1.18341486609993	1.2777567717349	0.164105749112118	0.175880037938037	0.162894109544406	0.723748499361473	NA	NA	0.768104212623061	0.761170822344033	82.9375311078844
a8279	PIK3CA_mut	186	Bexarotene	Retinioic acid X family agonist	5	13	2.07944154167984	NA	3.61077376934592	3.84466499036985	-0.233891221023929	1.09141383717153	0.950502149768825	0.236823876448876	0.214301132217706	0.246071217283217	0.723831586378835	NA	NA	0.809423975108437	0.686909801922561	82.9375311078844
a8280	NF1_mut	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.52987467033082	2.33220827175342	0.197666398577405	0.598885678210958	0.897455194885006	0.226627166617892	0.330056980437219	0.220252108076251	0.724014945369715	NA	NA	0.65191161523116	0.589779969463204	82.9375311078844
a8281	loss_cnaOV35	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.79592227095366	3.0519927449141	-0.25607047396044	1.75105706298527	0.943710692569409	0.235664950214983	0.146237652314929	0.27134425409894	0.724015007429368	NA	NA	0.436420191114294	0.764503532008975	82.9375311078844
a8282	loss_cnaOV20	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.9062402074614	2.20536310869854	-0.299122901237137	1.84623957122654	1.23203080564762	0.228511954253082	0.162017381654546	0.242788491867216	0.724103428725865	NA	NA	0.687802422748626	0.771890019980656	82.9375311078844
a8283	TP53_mut	193	GW-2580	CSF1R (cFMS)	22	10	2.99573227355399	NA	5.74709524870634	5.68110839011314	0.0659868585932033	0.635144129308938	0.541514872032363	0.108429407698333	0.103892731662339	0.121856041267246	0.724176353654713	NA	NA	0.194146485180447	0.765521100345849	82.9375311078844
a8284	loss_cnaOV55	1016	Temsirolimus	MTOR	7	24	-1.6094379124341	NA	-1.60625628022112	-2.15276260237818	0.546506322157058	1.582663267945	1.54902232465221	0.351215619185617	0.345308021754157	0.352807260075971	0.724294436668321	NA	NA	0.0386135275445626	0.438765507517547	82.9375311078844
a8285	PIK3R1_mut	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	0.564875490361238	0.326313657836533	0.238561832524705	1.69314551136432	1.68714446217307	0.141347673319901	0.140898600222774	0.141399766216482	0.724495484503448	NA	NA	0.83790195046886	0.805658616636679	82.9375311078844
a8286	loss_cnaOV39	230	GSK429286A	ROCK2	9	23	2.99573227355399	2.32630161961136	5.70355392457826	5.47425566258635	0.229298261991915	0.95686261616666	0.992058182616216	0.233312177229168	0.239635511010473	0.231133885098573	0.724546775175288	NA	NA	0.306164131298769	0.555313102387889	82.9375311078844
a8287	loss_cnaOV56	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.432180634259155	-0.77121359796662	0.339032963707465	1.67859148908728	0.849513778357752	0.366249516342149	0.201974670973586	0.39909060022884	0.724567070607926	NA	NA	0.0427152042764003	0.76127180153007	82.9375311078844
a8288	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	1.90663055498357	2.20530527943599	-0.298674724452425	1.8463268605129	1.2320302816662	0.228167431143744	0.161766982239242	0.242424824208458	0.72457837121244	NA	NA	0.687804817797906	0.772227679610932	82.9375311078844
a8289	loss_cnaOV16, loss_cnaOV17	310	YM201636	FYV1	6	26	1.63315443905142	NA	2.4438467524349	2.33685576060806	0.106990991826845	1.19434805676774	0.794256901205207	0.122449639485135	0.089581082516594	0.134705775504747	0.724643853293984	NA	NA	0.651914977274095	0.841281059573403	82.9375311078844
a8290	loss_cnaOV44	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.53463693821934	2.77119619414383	-0.236559255924485	0.644898134659725	1.74322119427637	0.139783720505794	0.366816467920633	0.135702374834126	0.724719306624864	NA	NA	0.323291164436265	0.648788386027645	82.9375311078844
a8291	gain_cnaOV51_(MYC)	1030	KU-55933	ATM	8	25	2.30258509299405	NA	4.31081123405357	4.09985346819538	0.21095776585819	0.788583173985944	1.0953035885895	0.204015612538905	0.267514921465912	0.192602095031803	0.72484830097125	NA	NA	0.531330710925104	0.559947950627605	82.9375311078844
a8292	loss_cnaOV43_(NF1)	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.83991163779347	3.89930234480343	-0.0593907070099613	1.91728889014952	1.47313468816272	0.039046291611945	0.0309763997043397	0.0403158702915569	0.724894311783904	NA	NA	0.0712125838553614	0.96300505241471	82.9375311078844
a8293	loss_cnaOV44	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.83991163779347	3.89930234480343	-0.0593907070099613	1.91728889014952	1.47313468816272	0.039046291611945	0.0309763997043397	0.0403158702915569	0.724894311783904	NA	NA	0.0712125838553614	0.96300505241471	82.9375311078844
a8294	loss_cnaOV33_(ZFHX3)	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	2.22635728014939	1.6489974697355	0.577359810413894	1.63841508649404	1.59558180485006	0.360834995228435	0.352389217587929	0.361849081419018	0.725441124684609	NA	NA	0.0420446916346005	0.546285069453103	82.987842173216
a8295	gain_cnaOV18_(CCNE1)	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.34793026692056	3.50025261108174	-0.152322344161182	0.306457905026661	0.95333505058359	0.16719716563482	0.497041654539571	0.159778394875901	0.725508969619102	NA	NA	0.795024659767819	0.526055093380924	82.987842173216
a8296	loss_cnaOV43_(NF1)	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.85304805534521	3.6496747500532	0.203373305292013	0.648485668754847	1.1086583822866	0.192057300391035	0.313612644181496	0.183440912495116	0.725602792928266	NA	NA	0.831677553880726	0.585833270797999	82.9885695671879
a8297	KRAS_mut	279	BIX02189	MAP2K5 (MEK5)	7	25	2.99573227355399	NA	4.55818733275976	4.39562181419026	0.162565518569501	0.795025109794907	0.726456282781013	0.219482026196953	0.204478470637787	0.223778804620106	0.725935624458212	NA	NA	0.526078461430696	0.637849647478991	83.0113264097358
a8298	gain_cnaOV72_(ASXL1)	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.09299576981155	-3.55343908524038	0.460443315428827	2.18448057162116	1.68267983311512	0.258453409242278	0.21077931358626	0.273636913194838	0.726039680737384	NA	NA	0.6836283918836	0.71523306330106	83.0113264097358
a8299	loss_cnaOV55	203	BMS-345541	IKBKB	7	25	2.77258872223978	NA	3.51126742951195	3.21036947321455	0.300897956297404	1.26834831821581	0.977220327933044	0.288776926424217	0.237236058877485	0.307912092796765	0.726112813985369	NA	NA	0.0932294169163778	0.576895233540662	83.0113264097358
a8300	gain_cnaOV95_(MECOM)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.6094379124341	NA	1.32899713511586	1.11631444134836	0.212682693767495	1.61758281055696	1.46652362633489	0.141603214254838	0.131481796405999	0.145025071501253	0.726151717886895	NA	NA	0.813817767566839	0.746963405042401	83.0113264097358
a8301	loss_cnaOV82	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.433308258023168	-0.771100835590218	0.337792577567051	1.67948199485686	0.849438860925041	0.364893830446749	0.201129025855285	0.397665556764373	0.726313718601027	NA	NA	0.0427205731576979	0.762214447245562	83.019458517569
a8302	loss_cnaOV40	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-1.92673377391568	-2.23789945411142	0.311165680195742	3.66798991755715	2.43273047469258	0.115579536605965	0.0848327523220063	0.127907996151963	0.726397847952445	NA	NA	0.420327905620688	0.880782426969532	83.019458517569
a8303	gain_cnaOV72_(ASXL1)	1268	XAV 939	TNKS1 (tankyrase-1)	5	27	1.6094379124341	NA	2.72349317696696	2.88037553381856	-0.156882356851595	0.214301615277472	1.1566924114096	0.145306978705404	0.732063342819271	0.135630142727755	0.726506112616727	NA	NA	0.308806243801298	0.522375501027946	83.0218317832051
a8304	PIK3R1_mut	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.42525337037223	4.38017924445737	0.0450741259148559	1.43193976882073	0.907335322954662	0.0453726787427784	0.0314776688910432	0.0496774728973141	0.726854820798462	NA	NA	0.513239609305137	0.948703563402823	83.0317766735959
a8305	loss_cnaOV38	1043	JNK Inhibitor VIII	JNK	8	25	2.30258509299405	NA	4.61663700974427	4.38616388655784	0.23047312318643	0.913259433128319	1.03995243991482	0.227575930236775	0.25236325498107	0.221618907115894	0.726861332587994	NA	NA	0.376843730910212	0.558512981111518	83.0317766735959
a8306	loss_cnaOV40	346	THZ-2-102-1	CDK7	7	25	0.916290731874155	2.99573227355399	-0.932139238860367	-1.09505633312301	0.162917094262639	2.17033294910159	1.9401799549018	0.081936114429479	0.0750654844594596	0.0839700945528448	0.727066357361706	NA	NA	0.445483322136393	0.861552567717216	83.0317766735959
a8307	PTEN_mut	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.86875791405574	5.81575980499315	0.0529981090625897	0.828165203077665	1.33909063801458	0.0408593515052766	0.0639946098503484	0.039577686198425	0.727084317896078	NA	NA	0.572567670606312	0.916861529193759	83.0317766735959
a8308	loss_cnaOV84	1373	Dabrafenib	BRAF	6	26	2.30258509299405	NA	3.42712681088953	3.69687253254399	-0.269745721654452	3.56869337919654	1.56587932317738	0.132159869171688	0.0755866904192207	0.172264693493175	0.727189094721099	NA	NA	0.748429389052528	0.862780659092283	83.0317766735959
a8309	loss_cnaOV20	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.247807608185727	-0.0292121151470821	-0.218595493038645	1.22352016144521	0.923523844716357	0.225610850974577	0.178661128706242	0.236697183607405	0.727345405888717	NA	NA	0.550611282283257	0.719949490495087	83.0317766735959
a8310	gain_cnaOV19	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	0.983314484010481	1.32160787306865	-0.338293389058167	1.11148660021405	2.4082806338518	0.144307551881438	0.304361194271724	0.140470917011487	0.727400809238453	NA	NA	0.36546697282709	0.686002152500738	83.0317766735959
a8311	loss_cnaOV20	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	0.433629630265623	0.938988197174143	-0.50535856690852	1.64628916670516	2.14979762412634	0.242340496442807	0.306968287910156	0.235072623226055	0.727596885859376	NA	NA	0.418048217920694	0.571859077722848	83.0317766735959
a8312	loss_cnaOV43_(NF1)	1008	Methotrexate	Dihydrofolate reductase (DHFR)	5	26	-1.6094379124341	NA	0.816247651586185	0.517525097202775	0.29872255438341	1.42363544104056	1.18106668243952	0.245377219661144	0.209830793594931	0.252926069988184	0.727651202551818	NA	NA	0.432907110062978	0.677284640655452	83.0317766735959
a8313	loss_cnaOV39	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	2.34460501890182	2.06592979464595	0.278675224255871	0.76543191462728	1.73028311061941	0.178869900692172	0.364075783790083	0.161057587943576	0.727705148732023	NA	NA	0.948113558600353	0.634791047273431	83.0317766735959
a8314	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	4.13326266848267	4.01406531222245	0.119197356260221	1.16881746192553	1.55507018370587	0.0789756808178421	0.101981156290952	0.0766507888255972	0.727915843778247	NA	NA	0.331746829746428	0.848799662490822	83.0317766735959
a8315	TP53_mut	156	AZD6482	PI3Kbeta	12	7	1.63315443905142	NA	2.03841490433478	2.31215190964786	-0.273737005313078	1.66210372607295	1.34352396866492	0.175796495239407	0.16469309407051	0.203745531674508	0.727976582039673	NA	NA	0.948113978749226	0.700707480111028	83.0317766735959
a8316	loss_cnaOV57_(ZNRF3)	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	2.91713419771938	2.34430212675246	0.572832070966924	1.85262677567501	1.53200102729359	0.361582300938012	0.309199930870163	0.373911022748386	0.728154640327808	NA	NA	0.2303730946963	0.595625259962028	83.0317766735959
a8317	loss_cnaOV58	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	2.91713419771938	2.34430212675246	0.572832070966924	1.85262677567501	1.53200102729359	0.361582300938012	0.309199930870163	0.373911022748386	0.728154640327808	NA	NA	0.2303730946963	0.595625259962028	83.0317766735959
a8318	TP53_mut	286	KIN001-236	TIE2	22	10	2.32630161961136	NA	4.7654707398538	4.86019060751524	-0.0947198676614311	0.700355055512637	0.586254014927922	0.141759334653836	0.135245497145872	0.161567964141067	0.728191739631846	NA	NA	0.76306558936883	0.694765444939143	83.0317766735959
a8319	gain_cnaOV49	262	VX-11e	ERK	3	29	1.63315443905142	NA	3.01033713118016	2.84365073793047	0.166686393249689	1.64200988906898	1.08250267568932	0.147710477742478	0.101513635428956	0.153982430707199	0.728214752209035	NA	NA	0.392749905952449	0.878073740073264	83.0317766735959
a8320	loss_cnaOV42	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.47161885663445	4.30827855323126	0.163340303403197	0.69211872556652	0.576671020857123	0.277006194586933	0.236000410579122	0.283246942356181	0.728289816876844	NA	NA	0.256058532297588	0.678523330559474	83.0317766735959
a8321	loss_cnaOV85	1248	FK866	NAMPT	7	25	0	NA	-1.5900797431526	-1.74147559094101	0.15139584778841	3.404053915092	2.60035405701179	0.0544639080348529	0.0444751615469986	0.0582212439033733	0.728299561257488	NA	NA	0.0454211767345033	0.915792339444569	83.0317766735959
a8322	PIK3R1_mut	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.85601106706364	4.78378544505992	0.0722256220037147	0.348380540120221	0.705687973600036	0.107934330150647	0.207318187114558	0.102347814764731	0.728341963521172	NA	NA	0.76306614874679	0.733133633418074	83.0317766735959
a8323	loss_cnaOV21, loss_cnaOV22	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	4.50306208359654	4.16537267569998	0.337689407896562	0.715507877955085	0.99258913702511	0.34579272684719	0.47195763778545	0.340210662498938	0.728343332442607	NA	NA	0.0490260490955426	0.511815465138262	83.0317766735959
a8324	ARID1A_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	8	24	2.99573227355399	NA	5.66863524773038	5.73055280580694	-0.0619175580765603	0.333753203885522	0.517706614344073	0.128695478052579	0.185518992344409	0.119599704467769	0.728635746183222	NA	NA	0.383709927140685	0.700226979748591	83.0551331057569
a8325	loss_cnaOV84	261	TL-1-85	MAP3K7 (TAK1)	6	26	2.32630161961136	NA	3.65690481504005	3.5322203375239	0.124684477516147	1.40708937839371	0.85142686169472	0.129008422937362	0.0886116258360812	0.146441794504779	0.728831761212897	NA	NA	0.729570510814495	0.841936872395176	83.0674970295657
a8326	gain_cnaOV94	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.24747017110811	3.06995284618738	0.177517324920736	0.454130185830398	1.01676452866045	0.183442033586204	0.390895233260342	0.174590399170012	0.729011375251359	NA	NA	0.673281087051021	0.64231078674563	83.0708842098314
a8327	gain_cnaOV51_(MYC)	1010	Gefitinib	EGFR	8	22	-0.693147180559945	NA	0.796429610663879	0.972333784990964	-0.175904174327085	1.51802320855456	1.18761790376187	0.137613162829523	0.115877131084562	0.148115125049812	0.729036582089444	NA	NA	0.957666200206823	0.772805143177552	83.0708842098314
a8328	PTEN_mut	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	1.99682725334254	2.87079467245244	-0.873967419109906	0.350122987489513	1.24962452412536	0.721910078622901	2.49617263172726	0.699384016748241	0.729439067031627	NA	NA	0.0961225315890814	0.0183150048905729	83.1021181993706
a8329	loss_cnaOV52, loss_cnaOV53	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.02903462549062	2.36384132084103	-0.334806695350409	1.42721091814551	1.40133357032535	0.238089527796762	0.234588098432886	0.238920056180969	0.72957344556746	NA	NA	0.748907709931218	0.695750447658722	83.1021181993706
a8330	loss_cnaOV55	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.02903462549062	2.36384132084103	-0.334806695350409	1.42721091814551	1.40133357032535	0.238089527796762	0.234588098432886	0.238920056180969	0.72957344556746	NA	NA	0.748907709931218	0.695750447658722	83.1021181993706
a8331	gain_cnaOV4_(KRAS)	192	LFM-A13	BTK	6	13	2.77258872223978	NA	4.80780478807867	4.6869070210539	0.120897767024769	0.550380952593336	0.750191399857086	0.173357012322578	0.219661974955914	0.161155895745807	0.729773839973208	NA	NA	0.957242091678434	0.699299190929708	83.1149663521548
a8332	loss_cnaOV52, loss_cnaOV53	155	AP-24534	ABL	5	14	-0.669430653942629	NA	0.903174836767233	0.747613699286304	0.15556113748093	1.08828296421867	1.32505546478383	0.12217053170693	0.142941810719801	0.117399717683749	0.729993093694782	NA	NA	0.587060251584705	0.802128702284784	83.1192711436738
a8333	gain_cnaOV51_(MYC)	1495	AZD-2281	PARP1, PARP2	8	25	2.30258509299405	NA	3.7551518401534	3.49918339420492	0.255968445948475	0.838474950092138	0.939485716683345	0.278939312161285	0.305278584554431	0.272455920726626	0.730032078135722	NA	NA	0.144493415611027	0.478620621879144	83.1192711436738
a8334	loss_cnaOV43_(NF1)	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.66507011647135	3.3626666506892	0.302403465782143	1.32627985440759	1.2100686414347	0.246618389851303	0.228008790736867	0.249906042870099	0.730074443083381	NA	NA	0.328773391889189	0.653973539499352	83.1192711436738
a8335	gain_cnaOV48_(SOX17)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-2.41582766545169	-2.28649728544602	-0.129330380005665	2.27147834302605	1.57428714420001	0.0794265997732772	0.0569366555497824	0.0821517094147303	0.730256133356613	NA	NA	0.12582368526477	0.931337439253728	83.1217583392709
a8336	loss_cnaOV36	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.64987076633121	3.94878468399452	-0.298913917663305	1.08296036066437	1.23840702626725	0.243352165759386	0.276015566700824	0.241369688093807	0.730317058278525	NA	NA	0.700013333123431	0.689020691892994	83.1217583392709
a8337	NF1_mut	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.06309873833505	2.97594594192324	0.0871527964118024	0.693772367720252	1.04240919441701	0.0859560320167846	0.125621602224067	0.0836070871962565	0.730359102894981	NA	NA	0.0889594708925483	0.8348431025607	83.1217583392709
a8338	loss_cnaOV83	1248	FK866	NAMPT	5	27	0	NA	-0.921118545091888	-1.854142787042	0.93302424195011	3.39241988199793	2.64741105993035	0.338248827579707	0.275032063955661	0.352428928046654	0.731046866609118	NA	NA	0.0454300973285538	0.58547761309696	83.1460639655924
a8339	loss_cnaOV55	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-2.76335432531255	-2.01480064040559	-0.748553684906959	0.587024970343673	2.93646324997984	0.279709474177689	1.27516498057777	0.254916755696533	0.731117346829787	NA	NA	0.420391836259055	0.370271478300113	83.1460639655924
a8340	loss_cnaOV20	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.20556224335891	2.38494515087498	-0.179382907516073	1.09543966729617	0.832594123875188	0.205660393718489	0.163754255822082	0.215450604769058	0.731161842879756	NA	NA	0.651949292541117	0.742293789051228	83.1460639655924
a8341	KRAS_mut	346	THZ-2-102-1	CDK7	7	25	0.916290731874155	2.99573227355399	-0.702812126899093	-1.15926792447216	0.456455797573069	2.28557349883633	1.89591533028159	0.230534254420602	0.199711712533186	0.240757480190464	0.731268216374861	NA	NA	0.44551391410517	0.640787924005483	83.1460639655924
a8342	gain_cnaOV96	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	5.18552787683722	4.64738498649808	0.538142890339138	1.03798020726871	1.66690952374834	0.341832856799812	0.518451976801349	0.322838692005927	0.731341707507305	NA	NA	0.124311175314726	0.448517317026339	83.1460639655924
a8343	loss_cnaOV85	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.4771520586225	2.37012013400363	0.10703192461887	1.20234728008149	0.874634848655208	0.112751627096438	0.0890191431311059	0.122373267865369	0.731357310585617	NA	NA	0.735890541463987	0.831622355229204	83.1460639655924
a8344	gain_cnaOV48_(SOX17)	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	3.18205431131905	2.70422198313351	0.477832328185535	1.52510850565047	1.69872037833012	0.283126012669543	0.313310381795908	0.28128957201023	0.731406238190223	NA	NA	0.323342827030238	0.650416357773147	83.1460639655924
a8345	loss_cnaOV81_(RB1)	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	3.80850632340925	3.9139374647336	-0.105431141324351	0.717560893968709	1.11491216249376	0.097364481348749	0.146929887359425	0.0945645270283263	0.73144303455669	NA	NA	0.318380798771323	0.808730474021643	83.1460639655924
a8346	loss_cnaOV33_(ZFHX3)	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	0.72296274529276	0.956574198997739	-0.233611453704979	1.23918363956707	1.28273975590683	0.18277396658892	0.188520447047376	0.182119134165159	0.731568815418607	NA	NA	0.95766805270033	0.744210127732855	83.1460639655924
a8347	KRAS_mut	1042	BIRB 0796	p38, JNK2	7	26	2.30258509299405	NA	4.50719287431615	4.36796548126048	0.139227393055662	1.02931251004775	0.821427395466081	0.160850787963955	0.135262509390082	0.169494460282352	0.731602036492149	NA	NA	0.870054308693732	0.749226541641029	83.1460639655924
a8348	loss_cnaOV21, loss_cnaOV22	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.38148310746203	2.52419909096136	-0.142715983499328	0.925616285024985	0.606887739472411	0.225407027983104	0.154184823461134	0.235160432839516	0.731640806959311	NA	NA	0.85870431233328	0.816481774405104	83.1460639655924
a8349	gain_cnaOV4_(KRAS)	165	DMOG	Prolyl-4-Hydroxylase	6	13	8.29404964010203	NA	6.58803818114314	6.74822803609299	-0.16018985494985	1.79398678535658	1.4105253005892	0.104474214637853	0.0892926616056484	0.113567516217495	0.731877213647583	NA	NA	0.34063748902966	0.851832760327132	83.1460639655924
a8350	loss_cnaOV35	341	EX-527	SIRT1	5	26	2.99573227355399	NA	5.91308463111245	5.74643413423161	0.166650496880836	0.724748009941948	0.536055624719534	0.294521026753615	0.229942676067761	0.310882843488542	0.731980569112227	NA	NA	0.112179990309501	0.64597974404908	83.1460639655924
a8351	loss_cnaOV56	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	1.02576006240296	1.47684348881563	-0.451083426412661	0.703088646204625	1.85582160628204	0.250577022019452	0.641574044535742	0.243064001887748	0.732137307224124	NA	NA	0.616201782160962	0.433395348426139	83.1460639655924
a8352	loss_cnaOV52, loss_cnaOV53	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-3.75589685934173	-3.34957750436737	-0.406319354974362	0.403015543260606	2.02612158301334	0.227943508127833	1.00819772777751	0.200540460345951	0.732170872673189	NA	NA	0.683682620903972	0.487123255973527	83.1460639655924
a8353	gain_cnaOV94	1017	Olaparib	PARP1, PARP2	7	24	1.6094379124341	NA	4.25583587270726	3.88616180450808	0.369674068199178	0.837300525848524	1.23792832106837	0.316940013066941	0.441507029778285	0.298623160895243	0.732323297931808	NA	NA	0.0841570595792363	0.376213516681001	83.1460639655924
a8354	gain_cnaOV19	152	CP466722	ATM	3	29	2.77258872223978	NA	2.52375859495538	2.65965717708818	-0.135898582132796	0.175826099567411	0.847048429664444	0.165813930575163	0.772914729196347	0.160437794786576	0.732338850148859	NA	NA	0.557600994094179	0.478122427506101	83.1460639655924
a8355	loss_cnaOV1	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.54407557824194	2.77021978310701	-0.22614420486507	0.637717742443768	1.74354406049874	0.133619241632495	0.354614886514642	0.129703751105884	0.732351819901654	NA	NA	0.323350013147553	0.660789673349856	83.1460639655924
a8356	gain_cnaOV48_(SOX17)	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.41400332477243	4.53970366160198	-0.125700336829556	0.913223258935438	1.00094114411179	0.126266618238168	0.137644694875694	0.125582145932366	0.732606280843836	NA	NA	0.327484481631698	0.83885267845571	83.1460639655924
a8357	loss_cnaOV85	299	OSI-027	MTORC1/2	7	25	2.99573227355399	NA	1.71614602480282	1.47922647970408	0.236919545098743	1.12524598687635	2.0855064329214	0.122627827487207	0.2105491135822	0.113602883864934	0.732624983051491	NA	NA	0.783507352079301	0.695328947445347	83.1460639655924
a8358	loss_cnaOV21, loss_cnaOV22	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	2.61184686333204	2.86818412619671	-0.25633726286467	1.08125621143808	1.91047553594573	0.137321848049421	0.237073563280381	0.1341745853541	0.732756181877954	NA	NA	0.348368174439613	0.741695397283225	83.1460639655924
a8359	PIK3R1_mut	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.47561323994443	2.25905708534618	0.21655615459825	0.354064231394575	0.963862188036053	0.239412184399974	0.611629572818712	0.224675433154505	0.732767158251006	NA	NA	0.596030193953832	0.391553630778499	83.1460639655924
a8360	gain_cnaOV49	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.24829359240583	3.51546628525724	-0.267172692851412	0.842355210016484	1.13832414030308	0.238456491785738	0.317173431913817	0.234707042916859	0.732805188538703	NA	NA	0.727961306812615	0.651604718459662	83.1460639655924
a8361	loss_cnaOV34	1019	Bosutinib	SRC, ABL, TEC	5	26	0.693147180559945	NA	2.18903607422872	1.63396847816586	0.55506759606286	1.42136109373914	1.62523047648865	0.347208685661194	0.390518354911951	0.341531619110477	0.732830119845764	NA	NA	0.0420683073894688	0.46378848024808	83.1460639655924
a8362	loss_cnaOV52, loss_cnaOV53	1494	SN-38	TOP1	9	23	-2.99573227355399	NA	-3.94519834291505	-4.27667151473812	0.331473171823068	0.740859485169258	1.50162261723045	0.247069786399084	0.447417058779154	0.220743326598549	0.732871031598946	NA	NA	0.219658672727801	0.412869738366576	83.1460639655924
a8363	gain_cnaOV94	1007	Docetaxel	Microtubules	7	24	-4.38202663467388	NA	-4.63561410038792	-4.65235524362796	0.0167411432400408	1.70188008670988	1.35417859915615	0.0116821343915242	0.00983685241444084	0.0123625814574776	0.73312116080941	NA	NA	0.137115819224513	0.981485011086201	83.1460639655924
a8364	gain_cnaOV95_(MECOM)	208	SB-715992	KIF11	9	23	-2.05572501506252	NA	-1.46881419995884	-1.25814965051424	-0.210664549444592	1.58876942507871	1.98146193287829	0.111772555412838	0.132596049570979	0.106317737398356	0.733203006571452	NA	NA	0.0753116411188381	0.757357401722241	83.1460639655924
a8365	loss_cnaOV59	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	1.22827683955506	0.972163592351713	0.256113247203351	1.25981273651907	1.58942010680128	0.164217559092471	0.203294695933147	0.161136282413579	0.733222032346611	NA	NA	0.791882225164899	0.730259315444549	83.1460639655924
a8366	gain_cnaOV96	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	3.22343381987945	2.77391522778902	0.449518592090428	1.6952345089723	1.88482599948321	0.24159046399713	0.26516602258347	0.238493416481775	0.733359021683443	NA	NA	0.348372722726415	0.611999949865607	83.1460639655924
a8367	NF1_mut	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.0212018079030708	0.316975421418196	-0.295773613515125	0.78038408816842	1.17602743705807	0.258602919426736	0.379010307872003	0.251502306999764	0.733494934565603	NA	NA	0.14843677127848	0.536916630261946	83.1460639655924
a8368	gain_cnaOV96	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.68788311281715	4.46239626014143	0.22548685267572	0.700367777408528	0.70189584856845	0.321321635912662	0.321954921327274	0.321254005328015	0.733517861309477	NA	NA	0.0826684434700754	0.579690389501538	83.1460639655924
a8369	loss_cnaOV21, loss_cnaOV22	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.18857696027284	2.35944178463976	-0.170864824366926	0.657328400193132	1.6087324746462	0.109185437366898	0.259938296164784	0.106210838072691	0.733532406453368	NA	NA	0.244075507329587	0.736361497730983	83.1460639655924
a8370	loss_cnaOV33_(ZFHX3)	1378	Bleomycin (50 uM)	DNA damage	4	28	3.91202300542815	NA	2.55454173055201	1.96866883555888	0.585872894993139	3.57025316627171	1.73264881808023	0.293799447068955	0.164098417593435	0.338137127893166	0.733570706200536	NA	NA	0.134051289635229	0.76676402795098	83.1460639655924
a8371	loss_cnaOV1	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.754224005968562	-1.37565854288109	0.621434536912524	1.54029315606829	1.89982952091509	0.330901765384715	0.40345211849073	0.32710015823588	0.733649172433891	NA	NA	0.0753135970252432	0.567408616675799	83.1460639655924
a8372	gain_cnaOV95_(MECOM)	1025	SB 216763	GSK3A, GSK3B	6	17	2.30258509299405	NA	5.04727321013707	4.92913826514489	0.118134944992185	0.618982757454738	0.889625808611382	0.141784733805848	0.190853369612357	0.132791724170618	0.733714345753131	NA	NA	0.456870167535105	0.727977601532117	83.1460639655924
a8373	loss_cnaOV43_(NF1)	156	AZD6482	PI3Kbeta	3	16	1.63315443905142	NA	1.83979311837596	2.19541642902653	-0.355623310650575	1.55865223463082	1.55717272093985	0.228352026822005	0.228160780672673	0.228377562661086	0.733747534701821	NA	NA	0.948122795402269	0.742413386052509	83.1460639655924
a8374	gain_cnaOV72_(ASXL1)	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.10427793264431	2.32723763026987	-0.222959697625561	1.67279259504212	1.20910175482351	0.176255984963346	0.133285918580927	0.184401103328236	0.733907893290013	NA	NA	0.845201669565484	0.811772250158324	83.1460639655924
a8375	PIK3R1_mut	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-3.95261459077867	-4.78562506134832	0.833010470569644	2.54731757396572	1.98934457827954	0.403817907946488	0.327014770000898	0.418736140367429	0.734103069899445	NA	NA	0.353434828201967	0.635904958861553	83.1460639655924
a8376	loss_cnaOV85	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.6094379124341	NA	0.9700543219025	1.22113299466609	-0.251078672763595	2.09905378623377	1.31792143145709	0.16725504635828	0.119615168706131	0.190511108455079	0.73412961777789	NA	NA	0.813840419656404	0.771852469937891	83.1460639655924
a8377	SMARCA4_mut	326	GSK690693	AKT	3	29	2.32630161961136	NA	4.14099853794216	4.15306210845389	-0.0120635705117333	0.707268410371824	1.5097813869001	0.00820665153869756	0.017056566269362	0.00799027635153352	0.734145295222522	NA	NA	0.0949152814971823	0.98166746648969	83.1460639655924
a8378	loss_cnaOV38	281	CH5424802	ALK	8	24	1.63315443905142	NA	4.00688012422869	3.90118083252144	0.105699291707251	0.703117578398321	0.743292159379053	0.143981972032757	0.150329468291819	0.142204233387248	0.734169316952786	NA	NA	0.955979047844563	0.72264340216153	83.1460639655924
a8379	gain_cnaOV94	1042	BIRB 0796	p38, JNK2	7	26	2.30258509299405	NA	4.28818009739932	4.42693045966117	-0.138750362261849	1.04392762724605	0.81700677098555	0.160297145834533	0.132911859635214	0.169827677308568	0.734339862839164	NA	NA	0.870059722610889	0.752835011085953	83.1460639655924
a8380	loss_cnaOV52, loss_cnaOV53	1009	ATRA	Retinoic acid and retinoid X receptor agonist	8	23	2.30258509299405	NA	4.37021394299008	4.56086509404949	-0.190651151059406	1.05828873983109	0.879347751770093	0.205950655285728	0.180150410642973	0.216809732754343	0.734346432804543	NA	NA	0.530255903134614	0.656531655418173	83.1460639655924
a8381	KRAS_mut	166	FTI-277	Farnesyl transferase (FNTA)	3	16	0.0237165266173161	NA	2.21860943391288	2.48796770782971	-0.269358273916831	0.480329678999865	0.893809065320854	0.314818247963637	0.560777910866728	0.30135997090177	0.734428394300989	NA	NA	0.624591861945377	0.482595367273139	83.1460639655924
a8382	gain_cnaOV4_(KRAS)	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	3.73309437858786	3.48290530933906	0.250189069248798	1.85451463566082	1.68319144522523	0.145455526081447	0.134908112579898	0.148639698685802	0.734591648358941	NA	NA	0.699812128485321	0.755831656325814	83.1546244721239
a8383	PIK3CA_mut	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	2.33656744552055	2.06880035656783	0.267767088952723	1.7573884620086	1.49183116560471	0.171822712383669	0.152366477157065	0.179488869200681	0.734849145776549	NA	NA	0.948124453294947	0.771193821850547	83.1649389878269
a8384	SMARCA4_mut	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.20244969248673	3.88957979904928	0.312869893437446	1.81908917932768	1.17241288169827	0.254781389495248	0.171992608714807	0.26685982244092	0.734866547132311	NA	NA	0.700034708241445	0.796087706630386	83.1649389878269
a8385	gain_cnaOV4_(KRAS)	1046	681640	WEE1, CHEK1	4	7	0.693147180559945	NA	2.09348259690165	2.47085024342444	-0.37736764652279	1.69554921665207	1.7535425989764	0.217574829844547	0.22256366421962	0.215203010604403	0.734945717416319	NA	NA	0.648728541864575	0.73681412432672	83.1649389878269
a8386	loss_cnaOV52, loss_cnaOV53	328	SNX-2112	HSP90	8	24	0.940007258491471	NA	0.94809319145415	0.612167692827256	0.335925498626894	2.56286264741829	2.24745708835722	0.144491408689066	0.131074327750373	0.149469149096163	0.735324115081916	NA	NA	0.946073073781417	0.747137270971765	83.1978354634215
a8387	loss_cnaOV70	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.07312135563713	4.30642724774929	-0.233305892112159	0.486809278710175	0.842509124518314	0.283506720128889	0.479255228516421	0.276917941091197	0.735647444511418	NA	NA	0.319008413667364	0.515867758820925	83.1986824371547
a8388	gain_cnaOV49	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.22326186792648	4.41492223430687	-0.191660366380397	1.3232929534484	0.824830086814355	0.221395074633204	0.144835930608521	0.232363452114876	0.735652402545966	NA	NA	0.870062295202943	0.827034832072411	83.1986824371547
a8389	gain_cnaOV50	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.39772968120171	4.45967757518654	-0.0619478939848284	0.519086158954923	0.565075964210315	0.110493624315833	0.119340292389125	0.109627550822126	0.735667952798982	NA	NA	0.366907300332615	0.83589051426447	83.1986824371547
a8390	loss_cnaOV38	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	1.6094379124341	NA	1.43128797465977	1.3132422742367	0.118045700423077	1.62429661471495	1.28545581198995	0.086639546258114	0.0726749654919356	0.0918317839648922	0.735682343332086	NA	NA	0.582537592313335	0.863887865539957	83.1986824371547
a8391	loss_cnaOV70	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.38201734016277	4.45916685550143	-0.0771495153386663	0.550508383921566	0.561276429519079	0.137628135929645	0.140142307713988	0.137453688202746	0.735916933160688	NA	NA	0.366909147676971	0.835452250926556	83.2011218770988
a8392	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.243256400810231	-0.0300549313277294	-0.213201469482502	1.22688768580168	0.923041009608975	0.220005341854191	0.173774235367918	0.230977245066088	0.735927540320211	NA	NA	0.550665637944034	0.727137432047075	83.2011218770988
a8393	ARID1A_mut	150	Bicalutamide	ANDR (androgen receptor)	5	14	0.0237165266173161	NA	2.88184090271572	3.00928181378222	-0.127440911066499	0.451279346746297	0.647798705440002	0.209845897007519	0.282399165805707	0.196729184538795	0.735967087211174	NA	NA	0.850704112906022	0.64172703799634	83.2011218770988
a8394	loss_cnaOV54	221	TAK-715	p38a	10	22	2.99573227355399	2.32630161961136	4.39578039352922	4.22437654483213	0.171403848697095	0.567214795310293	1.00894287247772	0.190555109495688	0.302185080703561	0.169884592450876	0.736083776437961	NA	NA	0.52334472283492	0.545424162652852	83.2011218770988
a8395	loss_cnaOV40	225	Genentech Cpd 10	AURKA, AURKB	7	25	2.32630161961136	NA	3.17101382446302	2.75263133913838	0.41838248532464	1.51132376630752	1.93705830358219	0.224970123179062	0.276831804443092	0.215988586688861	0.73619909077065	NA	NA	0.348393990250819	0.555562213311013	83.2011218770988
a8396	gain_cnaOV95_(MECOM)	1194	SB-505124	TGFR1 (ALK5)	8	24	2.30258509299405	NA	4.68781837005759	4.55531013395351	0.132508236104088	0.630286735879881	1.0282408846894	0.13942249382128	0.210234847984079	0.128868865338023	0.73645733388157	NA	NA	0.94338795438128	0.669722812985411	83.2011218770988
a8397	loss_cnaOV87, loss_cnaOV88	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.212440096601	1.91109290722858	0.301347189372415	0.779288748939179	1.38172511632904	0.223227934043	0.386695162457599	0.218094891531705	0.736484147341412	NA	NA	0.839739052066955	0.596210429199858	83.2011218770988
a8398	gain_cnaOV49	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.57743090426021	4.39827354964735	0.179157354612862	0.127514735004996	0.989731432724178	0.187258517439288	1.40499334924581	0.181016130931339	0.736532657315216	NA	NA	0.787360229492696	0.373316528406156	83.2011218770988
a8399	loss_cnaOV56	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.67243769736449	3.47002227401167	0.202415423352829	0.548616469487258	1.15286557128947	0.180455344983222	0.368956155366623	0.175575911358364	0.736655831035742	NA	NA	0.72797771995426	0.624703190619228	83.2011218770988
a8400	loss_cnaOV1	272	AR-42	HDAC	3	27	1.63315443905142	NA	0.546280104599073	0.267188627182646	0.279091477416427	1.72276592204419	1.86760411339317	0.150240368239856	0.162001972435852	0.149438243048929	0.736707865128014	NA	NA	0.4880814788785	0.811690762180934	83.2011218770988
a8401	gain_cnaOV26	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	2.45236691702767	2.75708573301542	-0.304718815987752	2.02253504026564	1.22697015942058	0.226520991768262	0.150661822871425	0.248350633182189	0.736775112516458	NA	NA	0.94159183195472	0.821670479134262	83.2011218770988
a8402	loss_cnaOV34	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-1.87436490833306	-2.0104166754878	0.136051767154741	1.98623572260513	2.05831939712919	0.0663938961327452	0.0684972914374417	0.0660984720566191	0.736812599518122	NA	NA	0.280301040069454	0.893288356516693	83.2011218770988
a8403	loss_cnaOV55	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.790081825906	-3.36754947028185	-0.422532355624149	0.45691497154232	1.95365995224964	0.236941454084335	0.924750515829866	0.21627732868128	0.736843860490849	NA	NA	0.683722990655549	0.455906794847768	83.2011218770988
a8404	loss_cnaOV21, loss_cnaOV22	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-2.53158626334423	-1.93562442217637	-0.595961841167862	3.70607928932123	1.87368978356317	0.291831650874394	0.160806554486052	0.318068575916836	0.737148499527697	NA	NA	0.280303431222464	0.807968639176069	83.2256160840344
a8405	loss_cnaOV52, loss_cnaOV53	165	DMOG	Prolyl-4-Hydroxylase	5	14	8.29404964010203	NA	6.775560721458	6.66981356776983	0.105747153688167	1.23664100575296	1.61516715640046	0.0689119529588176	0.0855116021514915	0.0654713372972702	0.737503241665075	NA	NA	0.34071403530781	0.8834086958069	83.2272335497457
a8406	gain_cnaOV94	330	XMD13-2	RIPK	7	25	2.32630161961136	NA	3.97472440376456	4.11462557977493	-0.139901176010373	0.999632592105505	1.15780964886376	0.124031343226553	0.139952595698888	0.120832622312025	0.737612921669334	NA	NA	0.82040610306965	0.758153483786576	83.2272335497457
a8407	ARID1A_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	9	23	2.99573227355399	NA	4.21750688162533	3.96037021033876	0.257136671286567	1.5635400485122	1.48345164736202	0.170829361362611	0.164458001271696	0.173336739181102	0.737904908517292	NA	NA	0.331822396002258	0.677813031607868	83.2272335497457
a8408	loss_cnaOV55	173	FH535	unknown 	3	15	3.46573590279973	NA	2.55448499951476	2.48529466553155	0.0691903339832081	0.578460570821771	1.54573015103394	0.0473812096856783	0.119611149788334	0.044762233522408	0.737965874222969	NA	NA	0.124092676809989	0.897113755259006	83.2272335497457
a8409	loss_cnaOV39	288	KIN001-055	JAK3, MNK1	9	23	2.32630161961136	NA	3.92423380995175	3.7527610319225	0.171472778029253	1.31349241722784	0.915420852722297	0.165413820417478	0.130547215789148	0.187315787617601	0.738063452997396	NA	NA	0.718372133416618	0.726275798992731	83.2272335497457
a8410	loss_cnaOV55	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	-0.0690843839400932	0.168787565000735	-0.237871948940829	0.538757804112907	1.46053642168912	0.176909145765415	0.441519263618831	0.162866153427197	0.738213194389861	NA	NA	0.870902605574573	0.61553441189738	83.2272335497457
a8411	gain_cnaOV4_(KRAS)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.36482082599686	3.52600795760175	-0.161187131604895	1.61356905131726	0.951799721449688	0.143758595834538	0.0998947838478356	0.169349841119296	0.738253284395033	NA	NA	0.727984447907095	0.808155219664384	83.2272335497457
a8412	loss_cnaOV87, loss_cnaOV88	308	XL-880	MET	3	29	1.63315443905142	NA	0.0131329560922876	0.277922412220443	-0.264789456128156	0.728721682230681	0.991208577209644	0.271326142378613	0.36336157216787	0.267137979045304	0.738284783196307	NA	NA	0.370360590759147	0.606838471132626	83.2272335497457
a8413	loss_cnaOV55	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	0.693147180559945	2.97587431132703	2.76977527569025	0.206099035636782	2.08489442142445	1.38460240090705	0.131250458435993	0.0988534640022538	0.148850699306723	0.738392755871919	NA	NA	0.96894341691468	0.799374342804086	83.2272335497457
a8414	loss_cnaOV81_(RB1)	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	3.11354087230377	2.74247727756905	0.37106359473472	0.17632311115569	1.29772375794193	0.301092458321635	2.10445240163144	0.285934192437991	0.738427055627006	NA	NA	0.0961676453818114	0.164841304410075	83.2272335497457
a8415	SMAD4_mut	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.754463044170249	-0.824467972858995	0.0700049286887454	0.591859269127437	0.834833292159621	0.0860992798835896	0.118279686304401	0.083854979606348	0.738442071222739	NA	NA	0.0800491325190553	0.843545680804831	83.2272335497457
a8416	loss_cnaOV83	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.97423320766742	2.89256176867388	0.081671438993534	1.01914928905248	1.2904170289192	0.0649405862706676	0.0801368748139591	0.0632907325021421	0.738535195287858	NA	NA	0.233599275919395	0.879647919803909	83.2272335497457
a8417	loss_cnaOV40	219	AT-7519	CDK9	7	25	2.32630161961136	NA	1.80307796656666	1.41220403311942	0.390873933447241	1.56752142315595	1.7445809497368	0.228496289991604	0.249357953054497	0.224050327676804	0.738705139948357	NA	NA	0.318205303853363	0.581588733415762	83.2272335497457
a8418	loss_cnaOV42	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.68557061954423	3.53703125670303	0.148539362841198	1.26074882200143	0.928016529965232	0.153694512180179	0.117818363379783	0.160061117496219	0.738716646398472	NA	NA	0.729611118924832	0.833110232064055	83.2272335497457
a8419	gain_cnaOV50	1061	SB590885	BRAF	4	29	1.6094379124341	NA	3.66959848034844	3.96311794065729	-0.293519460308842	1.68954282269835	1.23977205559126	0.227504615644953	0.17372715054364	0.236752763530276	0.73880121453656	NA	NA	0.574758425736545	0.756769970364624	83.2272335497457
a8420	gain_cnaOV18_(CCNE1)	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.56213805177372	5.85956264246201	-0.297424590688288	1.49705586712681	1.26856116862149	0.229986083612085	0.198673006946035	0.234458217739307	0.738856860608617	NA	NA	0.572639142233606	0.726131044676797	83.2272335497457
a8421	ARID1A_mut	330	XMD13-2	RIPK	8	24	2.32630161961136	NA	3.94217795238175	4.13130361256963	-0.189125660187882	1.04391805800119	1.15027820947851	0.167908785647026	0.181169066612378	0.164417319766167	0.738866519484387	NA	NA	0.820409538351496	0.672489696111968	83.2272335497457
a8422	TP53_mut	1164	XMD8-92	MAP2K5 (ERK5)	17	6	2.30258509299405	NA	2.96518239074518	2.80153380214003	0.163648588605148	0.872372605489092	0.815380394695237	0.190478202674914	0.187590242489789	0.20070213813065	0.739026478806357	NA	NA	0.332942086999495	0.687546537200804	83.2272335497457
a8423	loss_cnaOV16, loss_cnaOV17	1043	JNK Inhibitor VIII	JNK	6	27	2.30258509299405	NA	4.63323009510039	4.39954861745547	0.233681477644918	1.0599133076355	1.00443439575565	0.230548776133951	0.220472255571754	0.232649816287023	0.739153207884547	NA	NA	0.376932638952269	0.636758322515376	83.2272335497457
a8424	gain_cnaOV72_(ASXL1)	1046	681640	WEE1, CHEK1	3	8	0.693147180559945	NA	2.60500493288081	2.23185841161691	0.373146521263899	1.65601935915638	1.75857195458254	0.214908268569756	0.225327390770352	0.212187235382404	0.739316548919447	NA	NA	0.6488121670035	0.760532233388243	83.2272335497457
a8425	loss_cnaOV70	272	AR-42	HDAC	3	27	1.63315443905142	NA	0.542563888594711	0.267601540072019	0.274962348522692	1.72427545489407	1.86756055756144	0.148012846817006	0.159465442567344	0.147230753728127	0.739442457873926	NA	NA	0.48810119219651	0.814537414463681	83.2272335497457
a8426	gain_cnaOV48_(SOX17)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.29375670377904	4.53501209270435	-0.241255388925311	0.529577049786848	0.949629628433063	0.260312081296108	0.455562394598511	0.254052086941932	0.739495200834955	NA	NA	0.530289952412358	0.537591689845818	83.2272335497457
a8427	loss_cnaOV54	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	10	22	1.63315443905142	NA	2.80436208679036	2.89076971147946	-0.0864076246891026	0.693543495047784	0.853543879452652	0.106824609104303	0.124588616728572	0.10123395735028	0.739534157099648	NA	NA	0.0199793444371905	0.764673774891092	83.2272335497457
a8428	loss_cnaOV1	281	CH5424802	ALK	3	29	1.63315443905142	NA	4.06711719731812	3.91317342697896	0.153943770339165	0.511569400288213	0.747541958462578	0.209682988761148	0.300924508487871	0.205933283873151	0.739551154230043	NA	NA	0.955982747227277	0.669610110727773	83.2272335497457
a8429	loss_cnaOV58	1019	Bosutinib	SRC, ABL, TEC	5	26	0.693147180559945	NA	2.18354500719616	1.6350244525952	0.548520554600964	1.6783982539622	1.58590842818637	0.343043234043085	0.326811919224814	0.345871517454666	0.739554373485339	NA	NA	0.0420891571925411	0.527111962717416	83.2272335497457
a8430	NF1_mut	341	EX-527	SIRT1	4	27	2.99573227355399	NA	5.80031608885377	5.76931282556182	0.0310032632919457	0.685744474521692	0.554260048205069	0.0544612533317203	0.0452111018664358	0.0559363125528306	0.739556888842206	NA	NA	0.112222297122855	0.935774908018857	83.2272335497457
a8431	loss_cnaOV21, loss_cnaOV22	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.33700334045176	5.12231179471249	0.214691545739269	0.409330530089011	0.598797087717524	0.365079342864064	0.524494338823403	0.358538059290875	0.739745669551825	NA	NA	0.0122257808001925	0.471811842852165	83.2272335497457
a8432	gain_cnaOV19	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.0213981397825	2.3442359237332	-0.322837783950695	0.442803693150759	1.49924860640544	0.222199717174931	0.729076538755923	0.21533305588639	0.739830882420631	NA	NA	0.821716858991116	0.415977686430603	83.2272335497457
a8433	loss_cnaOV52, loss_cnaOV53	185	OSI-906	IGF1R	5	13	0.940007258491471	NA	2.33187837076524	2.16048903227262	0.171389338492625	1.48439550507377	1.26425182863445	0.129572711301008	0.115460696227389	0.135565822101873	0.740006049116241	NA	NA	0.688413930615665	0.826566285456628	83.2272335497457
a8434	SMAD4_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-2.16983481336994	-2.31596766573297	0.146132852363031	1.80977716970664	1.60731497256636	0.0897617048879393	0.0807463232541044	0.0909173714282671	0.740080347839717	NA	NA	0.125878079575568	0.886139988004715	83.2272335497457
a8435	gain_cnaOV94	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-3.19238893277628	-3.50602515997019	0.313636227193906	3.11666074647285	1.52642215307848	0.175365673800955	0.100632135707696	0.205471485434987	0.740085438934047	NA	NA	0.683750509829671	0.879119774224202	83.2272335497457
a8436	loss_cnaOV40	345	KIN001-270	CDK9	7	25	2.99573227355399	NA	5.15646753834306	5.20041226045033	-0.0439447221072689	0.764282224460926	0.780747638405543	0.0565218185665449	0.057498029786398	0.056285437118982	0.740150324185454	NA	NA	0.335708423946277	0.896246505509979	83.2272335497457
a8437	loss_cnaOV81_(RB1)	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	2.73212119875269	2.33042294898113	0.401698249771563	1.25653786128393	1.31636144437148	0.306478128862653	0.319686546779505	0.305158018330871	0.740152140231063	NA	NA	0.111494217579061	0.583596601132464	83.2272335497457
a8438	loss_cnaOV52, loss_cnaOV53	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.47864113855403	3.19536211207421	0.283279026479821	1.26056362976761	0.988405984989013	0.273397949895301	0.224724099434826	0.286601893130958	0.740202861236772	NA	NA	0.56824460093998	0.696446467801299	83.2272335497457
a8439	loss_cnaOV55	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-0.769752749326989	-0.498206312257431	-0.271546437069558	0.424962005207517	1.64503259159542	0.180612071303154	0.638989918491553	0.165070551463179	0.740232875640644	NA	NA	0.909919774817385	0.574994161186186	83.2272335497457
a8440	gain_cnaOV51_(MYC)	266	Zibotentan, ZD4054	Endothelin A Receptor	8	24	2.99573227355399	NA	5.79185896260078	5.68947823418347	0.10238072841731	0.487622221657574	0.477306090804895	0.213411880998735	0.209959111521388	0.214497008082721	0.740369803172977	NA	NA	0.38379691112769	0.614690480747885	83.2327659689286
a8441	PIK3R1_mut	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	1.7238361079959	1.93193545281617	-0.208099344820273	1.76401458151838	1.32416499702133	0.149844362920369	0.117969174971984	0.157155147046167	0.74065686854574	NA	NA	0.0349830305925396	0.811802697488841	83.2551736533277
a8442	gain_cnaOV96	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.2448829951407	5.24234850774514	0.00253448739555662	0.359527186823394	0.808566326980696	0.00336778237852205	0.00704950136858941	0.00313454482456716	0.740835049912118	NA	NA	0.12915733990634	0.992682966394014	83.2653381313323
a8443	loss_cnaOV20	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.901311686509538	0.782289651049516	0.119022035460022	0.1560354883886	1.16520824713546	0.109571984473152	0.762788239324141	0.102146578307032	0.741065076184619	NA	NA	0.35961654832547	0.718777926009507	83.2772368732041
a8444	gain_cnaOV51_(MYC)	292	Masitinib	KIT	8	24	2.99573227355399	NA	4.23023045392164	3.94128374253116	0.288946711390481	1.18864753370379	1.0052220266123	0.274954589039884	0.243088639144468	0.287445662491361	0.741262005960742	NA	NA	0.106164364947483	0.549777613499171	83.2772368732041
a8445	gain_cnaOV4_(KRAS)	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	4.90153692223895	4.7139140558337	0.187622866405245	0.833176289882943	1.32077320433751	0.15182572514396	0.225189877200664	0.142055324706073	0.741348715797316	NA	NA	0.426970488755346	0.656994346213954	83.2772368732041
a8446	loss_cnaOV20	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.41617629357552	2.52834598119956	-0.112169687624038	0.665931878937419	0.628022566929182	0.177145008979098	0.168440183105545	0.178607734069988	0.741491199620353	NA	NA	0.858725855449544	0.740282457435413	83.2772368732041
a8447	loss_cnaOV35	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.15465118544085	4.40589775246581	-0.25124656702496	0.597932464010351	1.12194224553731	0.235459602669811	0.420192215923253	0.223938948750998	0.741576391994414	NA	NA	0.353921862210656	0.481150028218312	83.2772368732041
a8448	loss_cnaOV52, loss_cnaOV53	299	OSI-027	MTORC1/2	8	24	2.99573227355399	NA	1.29965852898747	1.60818399726341	-0.30852546827595	1.22097322772272	2.09846289191218	0.159879218570012	0.252688151771673	0.147024505158065	0.741667980050764	NA	NA	0.783537115389781	0.617138120599257	83.2772368732041
a8449	gain_cnaOV18_(CCNE1)	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.04596339232747	2.32552277038862	-0.279559378061155	2.12289511530517	1.17619690691821	0.221091576519632	0.131687795617245	0.237680762818563	0.741679317956889	NA	NA	0.845220819421678	0.842101280842586	83.2772368732041
a8450	gain_cnaOV19	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.04596339232747	2.32552277038862	-0.279559378061155	2.12289511530517	1.17619690691821	0.221091576519632	0.131687795617245	0.237680762818563	0.741679317956889	NA	NA	0.845220819421678	0.842101280842586	83.2772368732041
a8451	loss_cnaOV43_(NF1)	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-2.44159480613926	-2.7859955882178	0.344400782078542	2.20783292608978	1.70300081114876	0.193634789747195	0.155990418481754	0.202231719341476	0.742005100553485	NA	NA	0.697545216541828	0.754241893640034	83.2772368732041
a8452	MLL2_mut	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.539125082089151	0.365476562798459	0.173648519290692	1.45567814979151	0.864295367138666	0.189282884588641	0.119290462191497	0.200913398235111	0.74201560753288	NA	NA	0.910066622874457	0.856838641044866	83.2772368732041
a8453	loss_cnaOV16, loss_cnaOV17	274	PXD101, Belinostat	HDAC	6	24	2.99573227355399	NA	0.48063775239433	0.948292773596487	-0.467655021202158	1.32962726420224	2.21590095904497	0.22424686290505	0.351718886783467	0.211045091746208	0.742051139662149	NA	NA	0.418160953629136	0.519624983296588	83.2772368732041
a8454	loss_cnaOV56	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.30331037047676	1.51781777525937	-0.214507404782611	0.743546203411397	1.76668528448703	0.124891974529853	0.288492367788913	0.121418006175839	0.742132525299497	NA	NA	0.31823038850022	0.708056044374043	83.2772368732041
a8455	loss_cnaOV36	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.16531070310725	0.898772149844093	0.266538553263154	1.06270120173084	1.29319175817675	0.20854159993807	0.250812319426231	0.206109072052039	0.742195932880743	NA	NA	0.957675606973911	0.716924760140319	83.2772368732041
a8456	gain_cnaOV4_(KRAS)	293	MP470	PDGFR	8	24	2.99573227355399	NA	3.86614706593255	4.11027461474536	-0.244127548812811	2.11991788061626	1.66009061854121	0.137300556647959	0.115158964903793	0.147056760688965	0.742230470881632	NA	NA	0.623749279000408	0.772680777606319	83.2772368732041
a8457	gain_cnaOV51_(MYC)	288	KIN001-055	JAK3, MNK1	8	24	2.32630161961136	NA	3.7221336976851	3.82727243509593	-0.105138737410833	1.13692772445758	1.00679514531246	0.101229378830803	0.0924761839729028	0.104429126322618	0.742257442501841	NA	NA	0.718389515073141	0.820158454888609	83.2772368732041
a8458	MLL2_mut	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	3.85429485446041	4.45838522644953	-0.604090371989113	0.932761796443391	0.741440303785385	0.798860000226775	0.647636271438756	0.814752541647603	0.742460658473598	NA	NA	0.0439849534385422	0.379018538953481	83.2901879286081
a8459	gain_cnaOV51_(MYC)	1001	AICAR	AAPK1 (AMPK) agonist	8	23	7.60090245954208	NA	8.68967955342073	8.77041743417242	-0.0807378807516965	1.11355207385337	1.28411623780184	0.0648451869749153	0.0725048092922216	0.0628742775575397	0.74266320586024	NA	NA	0.531806124606537	0.867768255536351	83.2959793905838
a8460	gain_cnaOV51_(MYC)	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.60565353294661	3.62696786772975	-0.0213143347831379	0.860660670477534	0.925781697678016	0.0232610869956533	0.0247650851424543	0.0230230677886559	0.742702985341686	NA	NA	0.0614097009546863	0.966584409617236	83.2959793905838
a8461	gain_cnaOV96	277	ABT-869	VEGFR and PDGFR family	5	27	0.0237165266173161	NA	2.84860896824077	2.69148529198197	0.157123676258791	0.70072179500533	0.548445880243461	0.275124590631418	0.224231181873821	0.28648893522373	0.742775648884334	NA	NA	0.137282160232786	0.654896381281777	83.2959793905838
a8462	loss_cnaOV56	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	0.352583003722028	0.910559409982059	-0.557976406260031	1.06076374562121	2.14595550162644	0.267327703812602	0.526013835374123	0.260013036541129	0.742879341782828	NA	NA	0.418167198297012	0.490483302195356	83.2972371863429
a8463	loss_cnaOV38	309	Y-39983	ROCK	8	24	2.99573227355399	NA	4.91601642291704	4.98038065396821	-0.0643642310511741	1.54899875115834	1.13954760516248	0.0516082973257788	0.0415521516741331	0.056482266084879	0.743069674379238	NA	NA	0.374692758218043	0.916071822955068	83.2972371863429
a8464	RB1_mut	1026	17-AAG	HSP90	3	30	0	NA	-1.30768530096007	-0.453146844023047	-0.854538456937024	0.632642393098082	2.37390975851597	0.371268633925005	1.35074485405935	0.359970910381712	0.743134824722821	NA	NA	0.0623420385164363	0.161965932571097	83.2972371863429
a8465	gain_cnaOV51_(MYC)	254	AC220	FLT3	8	24	0.0237165266173161	NA	2.56674756623302	2.49217676793339	0.0745707982996326	0.432744740608098	0.683260139118128	0.117670222619279	0.172320519008145	0.109139687844047	0.743138022988016	NA	NA	0.858729366270956	0.722592702579037	83.2972371863429
a8466	loss_cnaOV58	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.64103005697276	3.52647315709404	0.114556899878725	1.06552792772495	0.884344101872193	0.125805513042592	0.107511869842135	0.129538829553115	0.743231499877485	NA	NA	0.664676131484903	0.829732629704925	83.297874603332
a8467	gain_cnaOV95_(MECOM)	1219	PFI-1	BRD2, BRD3, BRD4	8	24	2.30258509299405	NA	2.4442702012076	2.33402424289273	0.110245958314863	0.71950617715466	0.918939426633276	0.125783581901249	0.15322447786458	0.11997086545603	0.743421158442496	NA	NA	0.609512449413855	0.73198516691867	83.3009781822585
a8468	loss_cnaOV42	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	4.58458426048491	4.35902747893824	0.225556781546679	0.71906463222939	1.0162720889335	0.227703504650197	0.313680817324254	0.22194526840089	0.743514552548398	NA	NA	0.513349308365519	0.604258162692958	83.3009781822585
a8469	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	3.41393973207283	3.68932400189321	-0.275384269820378	4.00987257607768	1.52789176578302	0.134903661423059	0.0686765638048652	0.180238074441908	0.743676789761654	NA	NA	0.748492313527823	0.886523253944348	83.3009781822585
a8470	TP53_mut	154	CHIR-99021	GSK3B	12	7	0.940007258491471	NA	3.28505623905197	3.37868737423181	-0.0936311351798382	1.00868758915311	0.955090744709492	0.0945671221687736	0.0928247122168424	0.0980337582564658	0.743738652180078	NA	NA	0.193314987526123	0.843068166503955	83.3009781822585
a8471	loss_cnaOV84	1133	JNJ-26854165	MDM2	6	27	2.30258509299405	NA	3.03904744686692	3.07425859148137	-0.0352111446144536	1.21340770358515	0.859866343505852	0.0380223776393375	0.0290183954745122	0.040949555568009	0.743741885531394	NA	NA	0.240856308426245	0.948382932760308	83.3009781822585
a8472	loss_cnaOV36	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.7590255977371	2.30239692089334	0.456628676843762	2.68170622899956	1.45085716552262	0.29273764903958	0.170275428347016	0.314730276484023	0.743801815002235	NA	NA	0.244146434173953	0.797285773584994	83.3009781822585
a8473	gain_cnaOV19	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.93686599787306	-2.14224683473014	0.205380836857078	1.37697764202124	1.29707024139596	0.157697338314403	0.149153356299674	0.158342108470579	0.744047639571324	NA	NA	0.609087964210584	0.824296083324606	83.3009781822585
a8474	loss_cnaOV1	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.7585402802091	4.41981017556833	0.338730104640764	0.898667568089299	0.993097681049672	0.343162588365552	0.376924812543258	0.341084377805351	0.744244201409913	NA	NA	0.0320029634248547	0.589213366292918	83.3009781822585
a8475	loss_cnaOV38	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.0414288113812	2.36030012487229	-0.318871313491094	2.20296473996216	1.14732479420803	0.22664143258625	0.144746444510306	0.277925932657284	0.744246839957751	NA	NA	0.749016626803618	0.796109855739726	83.3009781822585
a8476	loss_cnaOV39	158	PF-562271	FAK	4	14	0.940007258491471	NA	2.0414288113812	2.36030012487229	-0.318871313491094	2.20296473996216	1.14732479420803	0.22664143258625	0.144746444510306	0.277925932657284	0.744246839957751	NA	NA	0.749016626803618	0.796109855739726	83.3009781822585
a8477	PIK3R1_mut	207	AS601245	JNK 	3	15	2.07944154167984	NA	1.94656963034237	2.00285073686763	-0.0562811065252606	1.60187156369402	0.884523765014846	0.0561316147039338	0.0351345936845727	0.0636287104443327	0.744387955978072	NA	NA	0.483142908034941	0.957723575993181	83.3009781822585
a8478	PTEN_mut	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.127500568018485	0.692848491722821	-0.565347923704336	0.980901188917339	0.561427966782941	0.944436480066604	0.576355631017569	1.00698211908441	0.744407286279816	NA	NA	0.0155120825581317	0.423964633521175	83.3009781822585
a8479	loss_cnaOV40	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	4.55384737313996	4.81532350765424	-0.261476134514287	1.21282645511101	1.2385444642845	0.212018993956065	0.215592373840784	0.211115662016495	0.74454044341761	NA	NA	0.42699349412466	0.628286452142429	83.3009781822585
a8480	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.113789786598336	-0.144657312425555	0.258447099023891	1.25464132032885	1.26865286262635	0.203949606860371	0.205992816302392	0.203717743945225	0.744668745439267	NA	NA	0.768181322377342	0.720717571535048	83.3009781822585
a8481	loss_cnaOV38	283	GSK2126458	PI3K, MTOR	8	24	-2.05572501506252	0.0237165266173161	-2.50751004914823	-2.80707393830796	0.299563889159732	1.57592677010455	1.83540964818046	0.168459601590737	0.190087442413239	0.163213639776115	0.744780772895962	NA	NA	0.697557304293055	0.662352181850518	83.3009781822585
a8482	gain_cnaOV72_(ASXL1)	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.92351664177401	4.79107053162902	0.132446110144988	1.02723187901735	0.699839145380398	0.176177872877547	0.128934968676873	0.189252217483486	0.744897451938158	NA	NA	0.766227868922384	0.793761764980087	83.3009781822585
a8483	gain_cnaOV51_(MYC)	255	CP724714	ERBB2	8	24	2.32630161961136	NA	4.30205744871023	4.45274025261966	-0.150682803909425	0.913666184483949	0.968368512215012	0.157637011476642	0.164921069060395	0.155604815737718	0.744969472082228	NA	NA	0.787387098541549	0.697331124167582	83.3009781822585
a8484	loss_cnaOV85	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.866508810072315	0.783842687225583	0.0826661228467318	0.123708749119404	1.21336693631678	0.0760723530753489	0.66823182220477	0.0681295330971092	0.745031730669599	NA	NA	0.35967585610343	0.812929338993887	83.3009781822585
a8485	loss_cnaOV59	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	2.74446163215279	2.7952028833049	-0.0507412511521159	1.63768183649108	1.18619386861824	0.0409610028855661	0.0309835830266242	0.0427765245585216	0.745110863954969	NA	NA	0.0962000623521002	0.955625380167803	83.3009781822585
a8486	gain_cnaOV51_(MYC)	221	TAK-715	p38a	8	24	2.99573227355399	2.32630161961136	4.22795137481072	4.29460320512972	-0.0666518303189978	0.835765193806068	0.922159027757833	0.0738327848150198	0.0797494688854724	0.0722780218082961	0.745133156411964	NA	NA	0.523402108886179	0.852018657678227	83.3009781822585
a8487	loss_cnaOV38	333	T0901317	LXR	8	24	2.32630161961136	NA	4.85682183892519	4.71886172223722	0.137960116687972	1.05908399202884	1.14703607584644	0.122399693955824	0.130263621890543	0.120275307458108	0.74515099753244	NA	NA	0.00528830876230783	0.759716162292929	83.3009781822585
a8488	loss_cnaOV43_(NF1)	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.63840427516989	2.95475231172898	-0.31634803655909	0.466603688574098	1.33278638068708	0.252593419872889	0.677980145261653	0.237358395271121	0.745224331361486	NA	NA	0.233645925064354	0.35093410998148	83.3009781822585
a8489	loss_cnaOV42	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.18549693169057	0.796750285416461	0.388746646274106	1.09247432159208	1.37494439452634	0.287919154809138	0.355840534272311	0.282736267605954	0.745365090121305	NA	NA	0.165082851293067	0.550975384630117	83.3009781822585
a8490	loss_cnaOV70	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.14087609478184	2.75244479230355	0.388431302478293	0.117461294503745	1.27626309469604	0.314937430303631	3.30688763578975	0.30435049332113	0.745366234149994	NA	NA	0.0962012819391843	0.125588663880764	83.3009781822585
a8491	loss_cnaOV70	1262	UNC1215	LMBL3	3	30	0	NA	2.75236981264659	2.78321699372882	-0.0308471810822333	0.410264527852027	0.504248277145166	0.0618527588357002	0.0751885161598937	0.0611745889482787	0.745706851083427	NA	NA	0.111191290716712	0.912005902468931	83.329230018364
a8492	gain_cnaOV50	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.46388997644329	2.34163465659449	0.122255319848799	0.922240497179299	0.868275144856138	0.139908775771375	0.132563382569644	0.140802510094948	0.746098485077323	NA	NA	0.652024337943684	0.815668611914129	83.3442109598166
a8493	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.21968322709365	4.99651548311042	0.223167743983226	1.93079535069161	1.06354230807161	0.186190869345952	0.115583323682279	0.20983438297614	0.746153702591456	NA	NA	0.802358824221944	0.86190406294923	83.3442109598166
a8494	loss_cnaOV58	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.44760155192765	4.52596242737781	-0.0783608754501541	0.601501107103529	0.603728136547549	0.129842786940056	0.130275529878064	0.129794970130537	0.746205968579138	NA	NA	0.616636063595508	0.819758857062404	83.3442109598166
a8495	ARID1A_mut	287	KIN001-244	PDPK1 (PDK1)	8	24	2.99573227355399	NA	3.69508905342598	3.49413387912479	0.200955174301193	0.939140582339532	0.897199666054727	0.221521365157679	0.213977734622633	0.223980438139101	0.746266868487111	NA	NA	0.664690508834086	0.606156028309112	83.3442109598166
a8496	loss_cnaOV20	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	1.12842244985996	1.49179944710564	-0.363376997245678	1.38412007339005	1.85809724480487	0.201858614433776	0.262532856962097	0.195564036415025	0.746280109352406	NA	NA	0.616281400045201	0.628226363526307	83.3442109598166
a8497	loss_cnaOV38	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	NA	1.23428029382722	1.21022867767645	0.0240516161507689	1.33401672153039	1.22273975256945	0.0192608023174757	0.0180294712671793	0.0196702659746091	0.746397169968401	NA	NA	0.268990567572342	0.96469966621615	83.3474740325053
a8498	loss_cnaOV20	292	Masitinib	KIT	5	27	2.99573227355399	NA	4.26374936486482	3.96718172695544	0.296567637909381	0.701868844298361	1.0970315509538	0.281654892970629	0.422539966431836	0.270336470862242	0.746571812814315	NA	NA	0.10619123786034	0.455147803243339	83.3508112620481
a8499	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	274	PXD101, Belinostat	HDAC	5	25	2.99573227355399	NA	0.455120091771434	0.93469010487298	-0.479570013101546	1.68230116437875	2.14617364834506	0.229873929545829	0.285067872064776	0.223453499893332	0.746621799621268	NA	NA	0.41819512922478	0.59727231742043	83.3508112620481
a8500	gain_cnaOV26	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	3.59575585568863	3.70487945235413	-0.109123596665503	1.3030943866191	1.2288687070619	0.0884456837582543	0.0837418975832027	0.0888000451459177	0.746729569768097	NA	NA	0.200072886520544	0.900387838956247	83.3508112620481
a8501	loss_cnaOV21, loss_cnaOV22	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-2.39671369822443	-2.28840868216875	-0.10830501605568	2.11422632746816	1.58946931745809	0.066508628322135	0.0512267843080823	0.0681391045842168	0.746778439490101	NA	NA	0.125913840541962	0.93834094440722	83.3508112620481
a8502	gain_cnaOV4_(KRAS)	166	FTI-277	Farnesyl transferase (FNTA)	6	13	0.0237165266173161	NA	2.52181705652492	2.41018532983573	0.111631726689197	0.639908674319212	0.936730707165178	0.129784781386533	0.174449466258541	0.119171631542887	0.746970272444117	NA	NA	0.624713637031865	0.766337105245237	83.3624162857753
a8503	gain_cnaOV4_(KRAS)	206	Ruxolitinib	JAK1, JAK2, TYK2	8	24	1.65632149833295	0.0237165266173161	4.50789202810052	4.4332814418844	0.0746105862161199	0.470883738215212	0.584497355174878	0.133220622218768	0.158447999285166	0.127649142559074	0.747176690733607	NA	NA	0.366990597870249	0.7207902627426	83.3687354856721
a8504	MLL2_mut	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.09157390648314	2.5734690769534	-0.481895170470258	1.34211844670025	1.00968048471935	0.464716245832913	0.359055619610215	0.4772749179204	0.747312901147394	NA	NA	0.197791933400719	0.601408214090948	83.3687354856721
a8505	gain_cnaOV4_(KRAS)	193	GW-2580	CSF1R (cFMS)	8	24	2.99573227355399	NA	5.78628247663824	5.70653831498187	0.0797441616563681	0.572280809616205	0.618903591799167	0.131083860715802	0.139344462222747	0.128847469481555	0.747394900499604	NA	NA	0.194304449366756	0.743508433911184	83.3687354856721
a8506	loss_cnaOV16, loss_cnaOV17	306	TG101348	JAK2	6	26	2.32630161961136	NA	3.03780673630651	2.77473212946012	0.263074606846391	1.16902869394182	1.44690967951933	0.187319096109674	0.225036911591396	0.181818264519307	0.747803469552969	NA	NA	0.629001181815631	0.6470017225953	83.3687354856721
a8507	loss_cnaOV33_(ZFHX3)	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-4.27116846044466	-4.70448706325955	0.433318602814889	2.21406476811993	1.30379459472654	0.304044477437397	0.195711800781168	0.332351893900722	0.747843095182175	NA	NA	0.137204453065894	0.725827006127386	83.3687354856721
a8508	gain_cnaOV94	211	TL-2-105	CRAF	7	25	2.32630161961136	1.63315443905142	4.38914956473553	4.41475027218165	-0.0256007074461273	0.614524451865454	0.642647857236473	0.0401817666152366	0.0416593796526951	0.0398362916142224	0.747957774967085	NA	NA	0.273267541640825	0.925076463283734	83.3687354856721
a8509	gain_cnaOV49	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	2.0471519620388	1.64600026260676	0.401151699432047	1.01425238331452	1.51984529029861	0.268962030639107	0.395514672710068	0.263942456507025	0.748021471264785	NA	NA	0.328591855175185	0.580494241773271	83.3687354856721
a8510	gain_cnaOV26	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.29308276844344	3.49644223166337	-0.203359463219923	0.508176476952851	1.18194050514307	0.180950719544139	0.400174884991363	0.172055583453676	0.748023329836661	NA	NA	0.774833984865258	0.639937309896766	83.3687354856721
a8511	gain_cnaOV51_(MYC)	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	3.89767502543896	3.90401678776572	-0.00634176232675143	2.14404894500928	1.60386063622957	0.00366677134653661	0.00295784400888479	0.00395406071044922	0.748212828477615	NA	NA	0.149117512678357	0.994386963273722	83.3687354856721
a8512	PIK3CA_mut	271	VNLG/124	HDAC, RAR 	6	25	1.63315443905142	NA	4.13525105805955	4.37593960061698	-0.240688542557422	0.490194333315111	0.601891372864609	0.412025748872214	0.491006374818087	0.399887011857142	0.748318816843309	NA	NA	0.256208330292094	0.329539416666659	83.3687354856721
a8513	loss_cnaOV20	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	2.36005807997227	2.08038732664422	0.27967075332805	1.08831631641885	1.64207622309345	0.179423862033146	0.256975613715247	0.17031532969961	0.748402874131186	NA	NA	0.948144200372371	0.69697753756444	83.3687354856721
a8514	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.145217992561127	-0.138794366670715	0.284012359231842	0.985664681447115	1.28581896500298	0.224090039987776	0.288142980648212	0.220880518146024	0.74872858446069	NA	NA	0.768195475455797	0.679630616851025	83.3687354856721
a8515	gain_cnaOV95_(MECOM)	257	NPK76-II-72-1	PLK3	9	23	2.32630161961136	NA	3.12003562328206	3.27261135699815	-0.152575733716094	1.02090216071509	1.30949187715027	0.123131935126752	0.149451866777539	0.116515219665303	0.748740429215077	NA	NA	0.602568890937578	0.730452400206458	83.3687354856721
a8516	gain_cnaOV51_(MYC)	173	FH535	unknown 	5	13	3.46573590279973	NA	2.14098335339721	2.6336890934255	-0.492705740028291	1.19145912563427	1.51592151283248	0.341760840346716	0.413531383014085	0.325020613440386	0.748778117577765	NA	NA	0.124204725886913	0.485708235522835	83.3687354856721
a8517	loss_cnaOV41	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.61059194238966	3.46634527124892	0.144246671140748	0.635800696946738	1.18143013279989	0.128555470150307	0.226874037467171	0.122094965361088	0.748834756306007	NA	NA	0.728027823658555	0.702101405247184	83.3687354856721
a8518	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	333	T0901317	LXR	5	27	2.32630161961136	NA	5.08596371416156	4.69175694349211	0.394206770669451	0.998300716844469	1.13653850349517	0.352255327765765	0.394877779829209	0.346848584062181	0.748854289139278	NA	NA	0.00529051540145332	0.457559615283983	83.3687354856721
a8519	loss_cnaOV35	333	T0901317	LXR	5	27	2.32630161961136	NA	5.08595790461592	4.6917580193339	0.394199885282026	1.13869136136165	1.11604869859931	0.352249067764134	0.346186770759936	0.353210290712908	0.748865066488846	NA	NA	0.00529052177049111	0.504694418444304	83.3687354856721
a8520	gain_cnaOV26	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.38418367270983	4.12767585197279	0.256507820737039	1.88315308073779	0.949470698615603	0.247729600101274	0.1362118796187	0.270158753830999	0.748905190701889	NA	NA	0.531478901840704	0.836502309643852	83.3687354856721
a8521	loss_cnaOV1	308	XL-880	MET	3	29	1.63315443905142	NA	0.366249965330641	0.241393066437165	0.124856898893476	0.581554128522347	1.00078080746935	0.127608557412093	0.214695232601513	0.124759485755126	0.749005212465478	NA	NA	0.370437326112865	0.763978538017376	83.3687354856721
a8522	ARID1A_mut	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	1.29133666688994	2.29209170761404	-1.0007550407241	1.49561678728927	2.07291308128491	0.512280394727799	0.669125306180817	0.482777136079328	0.749120379289352	NA	NA	0.134140486582526	0.158048972879967	83.3687354856721
a8523	loss_cnaOV52, loss_cnaOV53	1192	GSK269962A	ROCK1, ROCK2	8	24	1.6094379124341	NA	2.71147625837147	2.3490439673262	0.362432291045272	1.93372745027242	1.28346441050998	0.248019210783971	0.187426770506988	0.282385929892096	0.74929467309461	NA	NA	0.242212325723691	0.632258086477407	83.3687354856721
a8524	loss_cnaOV56	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.1106884299168	4.39311827427693	-0.282429844360121	0.762688615165386	1.0863398895414	0.264492139260275	0.370308194909763	0.259982945557995	0.749349466725545	NA	NA	0.353977314516517	0.601808926715553	83.3687354856721
a8525	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.61472362456549	3.45311964135257	0.161603983212914	0.553568185360813	1.22684638496177	0.144131816327735	0.291931486466444	0.131723078939463	0.749358139127183	NA	NA	0.728029915832605	0.625120714248881	83.3687354856721
a8526	loss_cnaOV38	152	CP466722	ATM	8	24	2.77258872223978	NA	2.5999333163729	2.66257780789334	-0.0626444915204423	0.846922896770046	0.811796052244776	0.0763839007030191	0.0739671719342491	0.0771677705837789	0.749396282248225	NA	NA	0.557703584768153	0.857915666952302	83.3687354856721
a8527	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.89757128378159	4.77608910863067	0.12148217515092	0.783313850118117	0.648631232787069	0.181816177058664	0.155087485217581	0.187290048659744	0.749486690582213	NA	NA	0.763141315911273	0.75698138257583	83.3687354856721
a8528	gain_cnaOV72_(ASXL1)	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	3.64925793939201	3.54551820997822	0.103739729413794	0.790392310550665	0.941964787664393	0.112296067811964	0.131250934540998	0.110131218037372	0.749543941675265	NA	NA	0.144606135298071	0.801684126887986	83.3687354856721
a8529	loss_cnaOV39	1005	Cisplatin	DNA crosslinker	10	21	1.79175946922805	2.30258509299405	3.27668182352822	2.90303814897024	0.37364367455798	1.2077708735899	1.18045147828252	0.314251126645925	0.309366356424367	0.316526076193837	0.749655618095215	NA	NA	0.0899917430722961	0.42826442664554	83.3687354856721
a8530	gain_cnaOV50	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	3.24152152005141	2.7873855060534	0.454136013998013	1.88266968711439	1.85950383322131	0.243918718269078	0.241219167178539	0.244224295688216	0.74975398578825	NA	NA	0.348491889487662	0.675364307764631	83.3687354856721
a8531	loss_cnaOV40	222	BX-912	PDPK1 (PDK1)	7	25	2.32630161961136	NA	3.36190677360943	3.42336010942797	-0.0614533358185438	0.921155448480005	1.29712776820508	0.049915269166545	0.0667133174101589	0.0473764707879014	0.749774132150931	NA	NA	0.328917932083182	0.889540896365407	83.3687354856721
a8532	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	253	XMD14-99	EPHB3, CAMK1	7	25	2.32630161961136	NA	4.9123738498521	4.84541709340672	0.066956756445375	0.545606182389936	0.643144047781734	0.107155551979556	0.122719937212006	0.104108491210197	0.749778650929263	NA	NA	0.0506343302698424	0.787977285684497	83.3687354856721
a8533	loss_cnaOV1	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.49202497085155	4.20305441248622	0.288970558365327	0.558617095476288	1.00524284411577	0.294095531877243	0.517296303148304	0.287463432400268	0.749813963749325	NA	NA	0.211540777997613	0.485671095067414	83.3687354856721
a8534	gain_cnaOV50	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.52613926020389	3.56607732881154	-0.0399380686076505	1.0306845744298	0.91239548586724	0.0431994304368676	0.0387490698885692	0.0437727599777513	0.749838570714541	NA	NA	0.144607763431663	0.945138171489871	83.3687354856721
a8535	loss_cnaOV55	1053	MK-2206	AKT1, AKT2	7	25	1.38629436111989	0.693147180559945	1.33963106619124	1.30156452303188	0.0380665431593541	0.5964913814892	1.33993518337103	0.0310037748025119	0.0638174235884468	0.0284092422019891	0.74997984513858	NA	NA	0.0989708604876588	0.914373509030576	83.3734489206549
a8536	PIK3R1_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	3.97087184872124	3.8210130438052	0.149858804916043	0.823070310983489	0.906441812334195	0.168160924145453	0.182072907886784	0.165326447739805	0.750213249403338	NA	NA	0.940259867869443	0.735170022922345	83.3734489206549
a8537	loss_cnaOV70	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.69893485670143	4.46880731417552	0.230127542525902	0.274033328868925	0.722783583635203	0.327566969220441	0.839779392805085	0.318390660408316	0.750234022513551	NA	NA	0.0827405798983239	0.309885526702275	83.3734489206549
a8538	TP53_mut	287	KIN001-244	PDPK1 (PDK1)	22	10	2.99573227355399	NA	3.51155559376768	3.61657024635139	-0.105014652583712	0.901879524780305	0.929366654783394	0.115373734184144	0.116439779037331	0.112995933352255	0.750350345536237	NA	NA	0.664709541718216	0.76855078460087	83.3734489206549
a8539	loss_cnaOV55	1133	JNJ-26854165	MDM2	8	25	2.30258509299405	NA	3.23678388050118	3.01379982428756	0.222984056213621	0.658673135440794	0.98431880325482	0.242135281231841	0.338535222124092	0.226536418359871	0.75035675396133	NA	NA	0.240900191184653	0.474087366933478	83.3734489206549
a8540	gain_cnaOV51_(MYC)	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	4.55705926974672	4.81438670447727	-0.257327434730556	1.12642443106339	1.25985136186971	0.208627419410719	0.228446247821195	0.204252217776439	0.750507189598202	NA	NA	0.42703562428835	0.615336304631925	83.3734489206549
a8541	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	1.87075076214331	1.52647463547489	0.344276126668419	0.978820115994673	1.06852914816832	0.324578327737589	0.351725634815512	0.322196289412019	0.750967071488832	NA	NA	0.28996918145025	0.616221848986173	83.3734489206549
a8542	loss_cnaOV41	1239	YK 4-279	RNA helicase A	3	21	2.30258509299405	NA	1.87075076214331	1.52647463547489	0.344276126668419	0.978820115994673	1.06852914816832	0.324578327737589	0.351725634815512	0.322196289412019	0.750967071488832	NA	NA	0.28996918145025	0.616221848986173	83.3734489206549
a8543	loss_cnaOV38	1021	Axitinib	PDGFR, KIT, VEGFR	8	22	0.693147180559945	NA	2.73297736953403	2.44975308367814	0.283224285855888	0.856264216600682	1.09397632450784	0.272421070368101	0.330767396750821	0.25889434671569	0.751136338790939	NA	NA	0.197818372886291	0.469426173851482	83.3734489206549
a8544	gain_cnaOV4_(KRAS)	1061	SB590885	BRAF	7	26	1.6094379124341	NA	4.06462269477611	3.89063289757778	0.173989797198328	1.45429528132191	1.24974677951936	0.134680898757715	0.119638562699713	0.139220040451109	0.751213152595793	NA	NA	0.574827203533721	0.779400443796133	83.3734489206549
a8545	loss_cnaOV87, loss_cnaOV88	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.32990290103035	1.20467501964793	0.12522788138242	0.912653049921081	1.26810053397428	0.100324635443636	0.137213020208773	0.0987523291942403	0.751220565414563	NA	NA	0.269022958383702	0.842443131307173	83.3734489206549
a8546	SMAD4_mut	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.69225253488586	4.46776477143356	0.224487763452295	0.398354898848662	0.695089149993049	0.330711678275153	0.563537097450331	0.32296254869543	0.751498896482695	NA	NA	0.0544831702930903	0.450866101784577	83.3734489206549
a8547	loss_cnaOV1	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.08265228309233	4.30540607695052	-0.222753793858184	0.488746653199804	0.842712636167099	0.270594289062604	0.455765359005169	0.264329481128149	0.751590398807956	NA	NA	0.319127568688023	0.535168017649233	83.3734489206549
a8548	gain_cnaOV51_(MYC)	205	BMS-708163	g-secretase	8	24	2.32630161961136	0.940007258491471	5.18597562510674	5.02068090388307	0.165294721223669	0.464696286419404	0.657919428450057	0.267355067888153	0.355704846486517	0.251238546964746	0.751634008900781	NA	NA	0.112144806061326	0.446619948027099	83.3734489206549
a8549	loss_cnaOV35	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-0.489048491492942	-0.785275263725405	0.296226772232463	1.24696303161704	0.866782375972776	0.320361686268181	0.237558584113213	0.341754493912053	0.751635895904718	NA	NA	0.0427940293470458	0.63323293846838	83.3734489206549
a8550	loss_cnaOV85	135	Gemcitabine	DNA replication	6	13	0.0237165266173161	NA	-2.06215464421441	-2.22326915708058	0.161114512866177	2.89656701007068	2.60553305585653	0.0597961409912497	0.0556225740008844	0.0618355282440325	0.751770611572298	NA	NA	0.420656516013318	0.910025689990209	83.3734489206549
a8551	TP53_mut	258	STF-62247	stimulates autophagy	21	10	2.32630161961136	NA	4.50546821735225	4.45593386404	0.049534353312251	0.675406942353227	0.695927480794695	0.0726479025096584	0.0733400120817019	0.0711774641456702	0.751779121186493	NA	NA	0.0544841306218051	0.853821364002552	83.3734489206549
a8552	loss_cnaOV20	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.89870010368707	1.51002340929164	0.388676694395431	1.34531555667971	1.24834617095109	0.307824944429525	0.288911172152576	0.311353295616156	0.751830287922759	NA	NA	0.166581828294921	0.622080012663652	83.3734489206549
a8553	loss_cnaOV16, loss_cnaOV17	258	STF-62247	stimulates autophagy	6	25	2.32630161961136	NA	4.65394363137617	4.45002037666162	0.203923254714551	0.764145572677872	0.657588373507122	0.301145912346306	0.266864406476796	0.310107755748426	0.751850732605252	NA	NA	0.0544843758377966	0.566233683266862	83.3734489206549
a8554	loss_cnaOV16, loss_cnaOV17	257	NPK76-II-72-1	PLK3	6	26	2.32630161961136	NA	3.1290338046575	3.25292996125196	-0.123896156594456	0.891869701836283	1.29863690455035	0.0999047738250789	0.138917328775005	0.0954047710798382	0.752013970360898	NA	NA	0.60258628319645	0.785745625209395	83.3734489206549
a8555	loss_cnaOV43_(NF1)	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.89517435904441	4.79631910250487	0.0988552565395375	0.771028497799459	0.749610287560503	0.131368889578584	0.12821219555655	0.131875533433843	0.752088049703718	NA	NA	0.766252051678898	0.801045973281468	83.3734489206549
a8556	ARID1A_mut	208	SB-715992	KIF11	8	24	-2.05572501506252	NA	-2.12149483664424	-1.04936712784597	-1.07212770879827	1.87587951657346	1.80972712885635	0.587345864144992	0.57153335239603	0.592425063261221	0.752095926318034	NA	NA	0.0753911981394726	0.183972492161397	83.3734489206549
a8557	loss_cnaOV56	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.48073091430607	2.34926036883338	0.13147054547269	0.512311703050306	0.897360665632362	0.149915154751961	0.256622178821827	0.14650803239748	0.752122472998026	NA	NA	0.60955858072134	0.721268486649845	83.3734489206549
a8558	loss_cnaOV84	1259	BMN-673	PARP1	6	27	2.30258509299405	NA	2.26412854700171	1.81957784951193	0.444550697489782	1.55199010705699	1.34392266852541	0.322230174981881	0.286439130938003	0.330785920872633	0.752156081116753	NA	NA	0.0350111934110591	0.537365745023306	83.3734489206549
a8559	gain_cnaOV18_(CCNE1)	170	Shikonin	unknown	4	14	2.77258872223978	NA	-0.1630159346524	0.0320717943841243	-0.195087729036524	0.59095684642899	0.838929158437341	0.244371879056443	0.330121785059928	0.232543745886614	0.752180955769268	NA	NA	0.587505727794191	0.615343629000449	83.3734489206549
a8560	loss_cnaOV39	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	5.1557838872792	4.98745556961798	0.16832831766122	1.11110613388614	1.2249325846416	0.140376264971776	0.151496164522541	0.137418434101392	0.752229140296964	NA	NA	0.802390732185314	0.784653309485972	83.3734489206549
a8561	loss_cnaOV56	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.56876325534632	2.76766588547552	-0.198902630129199	0.614442917457738	1.74446320890952	0.117501802901396	0.323712137414099	0.114019389525294	0.75243264776307	NA	NA	0.323495746998154	0.692351692636948	83.3734489206549
a8562	loss_cnaOV38	271	VNLG/124	HDAC, RAR 	8	23	1.63315443905142	NA	4.32095391570469	4.33227674078888	-0.0113228250841901	0.839401252183508	0.488196997336705	0.0191150147398831	0.0134891686839118	0.0231931477374099	0.752594901738185	NA	NA	0.256238613137027	0.972025223195696	83.3734489206549
a8563	gain_cnaOV94	206	Ruxolitinib	JAK1, JAK2, TYK2	7	25	1.65632149833295	0.0237165266173161	4.54481424023901	4.42592764593427	0.118886594304733	0.460861009357547	0.58064342494809	0.212774322590506	0.257966267249348	0.204749746912852	0.752608670592925	NA	NA	0.3670284405096	0.58064575276516	83.3734489206549
a8564	loss_cnaOV82	333	T0901317	LXR	3	29	2.32630161961136	NA	4.78132994127778	4.75045745590557	0.0308724853722069	1.55677725874069	1.09180418518891	0.0273503834295254	0.0198310228382834	0.0282765772388619	0.752735892506175	NA	NA	0.00529278956462582	0.976056541033162	83.3734489206549
a8565	loss_cnaOV58	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.14148368414185	5.19993188366483	-0.0584481995229824	0.489126555715476	0.812724255746968	0.0751842135865256	0.119495044462443	0.0719163961327365	0.75280622134741	NA	NA	0.335798560089024	0.832899243482844	83.3734489206549
a8566	loss_cnaOV54	1502	Bicalutamide	ANDR (androgen receptor)	11	21	2.30258509299405	NA	4.5847161425985	4.48026079074789	0.104455351850605	0.588057148645771	0.608736142685445	0.173536333484981	0.177627892273998	0.171593806455782	0.752933709171684	NA	NA	0.616670923606218	0.642144833259667	83.3734489206549
a8567	loss_cnaOV34	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-0.48972506575135	-0.785154446893547	0.295429381142196	1.24752402272076	0.866705544287229	0.319487265572013	0.236812578965723	0.340864764382181	0.753062442354022	NA	NA	0.0427979273347588	0.634262386901959	83.3734489206549
a8568	loss_cnaOV35	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.17796391760353	3.26610969347433	-0.0881457758707969	1.3823785268998	0.965012356520757	0.0845859526643847	0.0637638491596635	0.091341603322673	0.753098077697113	NA	NA	0.568365038728272	0.910099487334314	83.3734489206549
a8569	loss_cnaOV54	152	CP466722	ATM	10	22	2.77258872223978	NA	2.61305394469024	2.66230883970549	-0.049254895015252	0.723465600109374	0.858417384256673	0.0600474343998326	0.0680818756383243	0.0573787249869167	0.75309984179936	NA	NA	0.557724837531351	0.868129761296715	83.3734489206549
a8570	KRAS_mut	1023	GW 441756	NTRK1	7	24	0.693147180559945	NA	2.18024927997467	2.33294928283505	-0.152700002860378	1.32198892632509	1.25049038018272	0.120652843520641	0.115507777576366	0.12211209720627	0.753115101821813	NA	NA	0.845247813287566	0.791406911085563	83.3734489206549
a8571	loss_cnaOV36	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.05674389646706	3.24759138383086	-0.190847487363797	0.967570159000164	1.25700930733576	0.153931939016195	0.197244081567179	0.151826630280328	0.753329435709489	NA	NA	0.602593199006658	0.774951420597078	83.3734489206549
a8572	loss_cnaOV52, loss_cnaOV53	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	2.45332656961775	2.3796020500683	0.0737245195494558	0.763297620199969	1.05988231802247	0.0738679410955308	0.0965868589111301	0.0695591560457498	0.7534077512867	NA	NA	0.413972951929242	0.871324747100533	83.3734489206549
a8573	gain_cnaOV95_(MECOM)	225	Genentech Cpd 10	AURKA, AURKB	9	23	2.32630161961136	NA	2.69000790531235	2.90446996095172	-0.214462055639372	1.63564234975696	1.94251962362652	0.114954358057514	0.131117940099337	0.110404061318562	0.753409036841792	NA	NA	0.348517278628405	0.755956100560986	83.3734489206549
a8574	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1091	BMS-536924	IGF1R	7	25	1.38629436111989	NA	2.28943351631398	2.42268132585001	-0.133247809536035	1.14401066134183	0.89317994457982	0.140457988895698	0.11647427252098	0.149183611146485	0.753527988004839	NA	NA	0.735976335211026	0.782879155260994	83.3734489206549
a8575	gain_cnaOV72_(ASXL1)	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.80463939640393	2.92396803001898	-0.11932863361505	0.844862928042449	1.30917082258841	0.0949154364100197	0.141240229218643	0.0911482531967225	0.753584002691878	NA	NA	0.23370228622656	0.799293379984462	83.3734489206549
a8576	loss_cnaOV54	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.32405490084265	2.06884066644617	0.255214234396484	0.996977014621548	1.478531608379	0.185737737535222	0.255988082627324	0.172613309685202	0.753656705501979	NA	NA	0.893201236594203	0.681640756235856	83.3734489206549
a8577	gain_cnaOV72_(ASXL1)	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.9046950682586	3.03184963430208	-0.127154566043479	0.867957602080131	1.12001306150172	0.116679198845017	0.146498591335271	0.113529538551086	0.753659366348752	NA	NA	0.436628739631152	0.783172392988523	83.3734489206549
a8578	loss_cnaOV54	293	MP470	PDGFR	10	22	2.99573227355399	NA	4.13412299000095	4.01066079006088	0.123462199940072	1.95483467376174	1.70020264436599	0.0693444185572636	0.0631573613857022	0.0726161674605037	0.753884569054932	NA	NA	0.623809165883921	0.865446509216801	83.3881607066276
a8579	ARID1A_mut	152	CP466722	ATM	8	24	2.77258872223978	NA	2.48788282731571	2.6999279709124	-0.212045143596688	0.637312730975492	0.861970401200786	0.26014375146583	0.33271757065346	0.246000492941862	0.754256427418842	NA	NA	0.557731400740729	0.468812948847056	83.3881607066276
a8580	loss_cnaOV85	1016	Temsirolimus	MTOR	7	24	-1.6094379124341	NA	-1.92760701496901	-2.05903530474338	0.131428289774366	1.51294754184881	1.58810351436403	0.0835606706256856	0.0868690328904348	0.0827580120474689	0.754346728106492	NA	NA	0.0387003357697293	0.84545596790205	83.3881607066276
a8581	loss_cnaOV39	306	TG101348	JAK2	9	23	2.32630161961136	NA	2.99401220270113	2.75755504171704	0.236457160984093	1.50375071725027	1.36610612409607	0.168401033768471	0.157244919833837	0.173088427621648	0.754432720577569	NA	NA	0.629034392422097	0.68814621561545	83.3881607066276
a8582	loss_cnaOV52, loss_cnaOV53	306	TG101348	JAK2	8	24	2.32630161961136	NA	2.7361464795009	2.85336266449145	-0.117216184990547	1.32047958305371	1.43286151910194	0.0832831413620114	0.0887678889509794	0.0818056619065421	0.754448960499972	NA	NA	0.629034472542272	0.834817036807676	83.3881607066276
a8583	gain_cnaOV94	225	Genentech Cpd 10	AURKA, AURKB	7	25	2.32630161961136	NA	3.15613313491394	2.75679793221213	0.399335202701809	1.48911867601489	1.94226676966329	0.214640048378519	0.26816882303195	0.205602654042749	0.754479933028956	NA	NA	0.348524637012494	0.569755292405673	83.3881607066276
a8584	loss_cnaOV81_(RB1)	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	2.07571389233016	2.34800645136748	-0.272292559037324	0.74141137707245	1.51172987475426	0.187375638648178	0.367262450318072	0.180119850500134	0.75456009168717	NA	NA	0.821755366371283	0.578139854153531	83.3881607066276
a8585	gain_cnaOV95_(MECOM)	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	2.2307329891902	1.97895960018062	0.251773389009581	1.94410644200175	2.01796541604115	0.125825322090616	0.129505969205237	0.124765958330203	0.754874778673061	NA	NA	0.134171949872741	0.758577108884914	83.3881607066276
a8586	gain_cnaOV18_(CCNE1)	177	GSK-650394	SGK3	4	15	2.77258872223978	NA	4.13506942315342	3.90486574526253	0.230203677890885	0.881441810927802	1.68118657465654	0.146631873878413	0.261167186576473	0.136929286351168	0.7549413719407	NA	NA	0.745149409015526	0.717798539012858	83.3881607066276
a8587	loss_cnaOV33_(ZFHX3)	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-3.78087728150578	-3.67787762808417	-0.102999653421613	2.85022760948274	1.56591716967428	0.0590857797485962	0.0361373432349516	0.065775926987912	0.755005924559941	NA	NA	0.24739596285919	0.947729425875694	83.3881607066276
a8588	PIK3CA_mut	1059	AZD8055	MTORC1/2	7	26	0.693147180559945	NA	-0.153260323952999	0.398073720015806	-0.551334043968805	0.82767256254227	1.18444852838399	0.49039457383316	0.666125795296793	0.465477419032317	0.755010045543065	NA	NA	0.148560031618583	0.179796093244399	83.3881607066276
a8589	gain_cnaOV48_(SOX17)	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.48931873567777	3.2028422625332	0.28647647314457	0.424013619503893	1.27658495340226	0.231374991073462	0.675630357062008	0.224408467592441	0.755056048803143	NA	NA	0.602602212846695	0.428060841685482	83.3881607066276
a8590	loss_cnaOV35	1003	Camptothecin	TOP1	5	26	-2.30258509299405	NA	-3.7490589147852	-3.68003501962961	-0.0690238951555964	2.36285663241428	1.62247364698768	0.0395917623478907	0.0292120538371684	0.0425423829125038	0.75523512745187	NA	NA	0.247397540991508	0.952672876821367	83.3881607066276
a8591	loss_cnaOV56	152	CP466722	ATM	3	29	2.77258872223978	NA	2.53754351806412	2.65823115055969	-0.120687632495561	0.903310175827862	0.81350764620834	0.147215841252932	0.133605970269242	0.148354638162372	0.755241878636987	NA	NA	0.557736965188669	0.841968880121988	83.3881607066276
a8592	loss_cnaOV21, loss_cnaOV22	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.69645464069998	4.46905533577567	0.227399304924311	0.0964224999219419	0.725996708083822	0.323647551536878	2.35836350549301	0.313223603347325	0.755266485808886	NA	NA	0.0827612594878415	0.125076717906609	83.3881607066276
a8593	loss_cnaOV58	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.4970624927233	4.48803302850696	0.00902946421634798	0.788972605312805	0.663587064492844	0.0132347737473106	0.0114445852182258	0.0136070527885424	0.755288756167218	NA	NA	0.0544960548297954	0.981747954472021	83.3881607066276
a8594	loss_cnaOV70	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.26058049575912	1.31499272592615	-0.0544122301670347	0.64438777508871	1.25917272832428	0.0443167863075112	0.0844401962149949	0.0432126815829684	0.755468507928079	NA	NA	0.0989965863828652	0.907645891441916	83.3881607066276
a8595	loss_cnaOV58	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	4.13225414516229	3.83741464847996	0.294839496682328	1.47160796015929	1.61985841538983	0.18424856376361	0.200351931128732	0.182015597092399	0.755808977730984	NA	NA	0.716903981916833	0.700532766272964	83.3881607066276
a8596	loss_cnaOV35	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.30197234223351	4.33462056356208	-0.0326482213285759	0.867439704770887	0.535239927025494	0.0551262599654405	0.0376374532420085	0.0609973577831028	0.755966350799646	NA	NA	0.256262074376116	0.938664720199312	83.3881607066276
a8597	gain_cnaOV72_(ASXL1)	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	-0.0414099482153643	0.141701291062142	-0.183111239277506	1.96511867479357	1.59334611774044	0.111944764236729	0.0931807537255946	0.114922449829784	0.756089492263345	NA	NA	0.464010264205437	0.868333574823896	83.3881607066276
a8598	loss_cnaOV41	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.232622567700323	-0.032024159681416	-0.200598408018907	1.2379030619977	0.921234985177386	0.206919300916948	0.162046943882009	0.217749446391554	0.756100028002833	NA	NA	0.550785537040196	0.744477655763178	83.3881607066276
a8599	loss_cnaOV52, loss_cnaOV53	151	QS11	ARFGAP	5	14	2.32630161961136	NA	3.81613819768288	3.74915136154847	0.066986836134403	0.970268630213569	1.60232049007493	0.0453189255255434	0.0690394742739012	0.0418061408746453	0.756254822799757	NA	NA	0.0666899444943078	0.914312908837247	83.3881607066276
a8600	gain_cnaOV4_(KRAS)	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	4.05343205111101	3.8808982955443	0.172533755566713	1.23073112967185	1.22911775015435	0.140333899937008	0.140188016218226	0.140372031520208	0.756408318022523	NA	NA	0.700130244727315	0.750962393744319	83.3881607066276
a8601	gain_cnaOV51_(MYC)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	NA	1.22934491171427	1.2118079999526	0.0175369117616733	0.74845372401763	1.36045007192517	0.0140435159030074	0.0234308564429832	0.0128905221320301	0.756418449147621	NA	NA	0.269057073408781	0.96355748289666	83.3881607066276
a8602	loss_cnaOV34	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.1304863368416	2.11260247919365	0.0178838576479472	0.813947934625884	0.516267158887464	0.0317324239363503	0.0219717464559538	0.0346407036358583	0.756424829373959	NA	NA	0.0431969202861519	0.964144247168534	83.3881607066276
a8603	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	229	LY317615	PRKCB (PKCbeta)	7	25	2.99573227355399	2.32630161961136	2.90960383771048	2.70405494323423	0.205548894476252	1.1845228246553	1.79607523971302	0.121515403187657	0.173528859214737	0.114443365139366	0.756434915248817	NA	NA	0.323523245125767	0.725363425627397	83.3881607066276
a8604	loss_cnaOV40	1052	RO-3306	CDK1	8	25	1.6094379124341	NA	3.41312132787029	3.50376304664362	-0.0906417187733295	0.979689131038682	0.890756123895857	0.0994318467036469	0.0925208986214124	0.101758176387151	0.756491812751473	NA	NA	0.795116635785332	0.820270097115781	83.3881607066276
a8605	gain_cnaOV19	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	3.08748374352436	2.79296417174331	0.294519571781052	1.70452012921147	1.56081934324619	0.187533888730869	0.172787382638479	0.188695490644362	0.756635281193647	NA	NA	0.968951571775822	0.797183080718035	83.3881607066276
a8606	loss_cnaOV33_(ZFHX3)	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.10706133310836	4.31004006190585	-0.20297872879749	0.579295529299691	0.846630332548715	0.246629174219078	0.350388909513716	0.239748944721173	0.756704439337677	NA	NA	0.31916400233023	0.567349784027297	83.3881607066276
a8607	gain_cnaOV26	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.17030350934037	4.32164929883866	-0.151345789498287	1.80824229337455	1.27931595866148	0.114668734190685	0.0836977378821534	0.11830211956133	0.756746550386299	NA	NA	0.373215340871866	0.89938155065951	83.3881607066276
a8608	loss_cnaOV40	1053	MK-2206	AKT1, AKT2	7	25	1.38629436111989	0.693147180559945	1.58483887490673	1.23290633659155	0.351932538315179	1.12188212255569	1.24170430896665	0.288781101536948	0.313698321097643	0.283427008969679	0.757002357620202	NA	NA	0.0990036605656242	0.489483362684601	83.3881607066276
a8609	loss_cnaOV36	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.79454936767611	2.2331175359672	0.561431831708902	1.5746099372577	1.81186262520461	0.312340163829141	0.356552958561075	0.309864458761326	0.75706101841969	NA	NA	0.112090201282792	0.608732781111145	83.3881607066276
a8610	gain_cnaOV19	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.34215247666935	3.49575297863483	-0.153600501965473	0.375065826447669	0.937078194672159	0.168543768372746	0.409529450924007	0.163914284676329	0.757170522462886	NA	NA	0.795118509770287	0.601189687208199	83.3881607066276
a8611	loss_cnaOV58	1003	Camptothecin	TOP1	5	26	-2.30258509299405	NA	-3.31338995674437	-3.76381751156054	0.450427554816167	2.44223872522418	1.59315957269433	0.25958933331692	0.184432238406514	0.282725950705874	0.75724235799107	NA	NA	0.24741129001855	0.709178227900576	83.3881607066276
a8612	loss_cnaOV38	1018	ABT-888	PARP1, PARP2	8	23	1.6094379124341	NA	4.45070318096385	4.24702196526193	0.203681215701918	1.00294804773776	0.727700270290677	0.253705139106006	0.203082518741963	0.279897128003757	0.757387553353998	NA	NA	0.227290896543366	0.609313145201602	83.3881607066276
a8613	gain_cnaOV19	192	LFM-A13	BTK	3	16	2.77258872223978	NA	4.84655967448502	4.70230881116985	0.144250863315174	0.935661866183833	0.659522585674778	0.206750404113156	0.154169864700708	0.218720126419304	0.757422626392863	NA	NA	0.957275019311448	0.818779845233674	83.3881607066276
a8614	KRAS_mut	288	KIN001-055	JAK3, MNK1	7	25	2.32630161961136	NA	3.87404143114048	3.780532720232	0.0935087109084805	0.605309407165784	1.12141988134629	0.0900060576569786	0.154480848639562	0.0833842100215144	0.757492487300273	NA	NA	0.718449955145332	0.77359585991043	83.3881607066276
a8615	gain_cnaOV4_(KRAS)	1248	FK866	NAMPT	7	25	0	NA	-1.94656610198762	-1.6416594104672	-0.30490669152042	2.68324084369813	2.80050536704939	0.109779419612876	0.113633739675857	0.108875596207719	0.757502668710355	NA	NA	0.0455107309195599	0.797763776879527	83.3881607066276
a8616	loss_cnaOV33_(ZFHX3)	1026	17-AAG	HSP90	4	29	0	NA	-0.534818634006756	-0.530282299570503	-0.00453633443625256	1.00951909005434	2.41396639699319	0.00195904477412401	0.00449355983551377	0.00187920363841973	0.757597099582365	NA	NA	0.0623928448538256	0.994785047441715	83.3881607066276
a8617	loss_cnaOV84	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.888760408616687	0.784979210597984	0.103781198018703	0.141368242849488	1.16577300048243	0.0955185957786114	0.734119600886577	0.0890235045551365	0.757747114416182	NA	NA	0.359858938525864	0.75191307023931	83.3881607066276
a8618	MLL2_mut	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	-0.278065279663631	0.337043009724362	-0.615108289387992	0.356027426607704	1.16817346971661	0.542674592596048	1.72769916983323	0.526555606109777	0.757751167331512	NA	NA	0.148574890876927	0.0715521130854976	83.3881607066276
a8619	loss_cnaOV59	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-2.34321712440707	-2.2920528642106	-0.0511642601964675	2.21191568419083	1.55323338457712	0.031414917970496	0.02313119824691	0.032940484478704	0.757756248702656	NA	NA	0.125970161687926	0.966782838635392	83.3881607066276
a8620	loss_cnaOV58	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.45011100429652	3.27509493075825	0.175016073538266	0.624291011807088	1.17151609377013	0.157079040937918	0.280343734297343	0.149392803452691	0.757794014886093	NA	NA	0.951154574565744	0.636026326437795	83.3881607066276
a8621	loss_cnaOV38	230	GSK429286A	ROCK2	8	24	2.99573227355399	2.32630161961136	5.6989687510975	5.48533814799626	0.21363060310124	0.997838616182327	0.979643825586656	0.217122062270603	0.214093340983915	0.218069667282707	0.75784112835753	NA	NA	0.306406714121621	0.608051298472485	83.3881607066276
a8622	loss_cnaOV54	1009	ATRA	Retinoic acid and retinoid X receptor agonist	10	21	2.30258509299405	NA	4.53717284066269	4.49951810954438	0.037654731118316	1.00009029868271	0.895988041663493	0.0405088145385235	0.0376513312527017	0.0420259304447927	0.7578460592072	NA	NA	0.530405104006621	0.920581829215421	83.3881607066276
a8623	gain_cnaOV18_(CCNE1)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.34905962202084	2.14723521066584	0.201824411354994	0.125283794287695	1.35893682937247	0.153870325275913	1.61093789106942	0.148516404142341	0.757922964280616	NA	NA	0.687961072694226	0.455486745226325	83.3881607066276
a8624	gain_cnaOV19	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.34905962202084	2.14723521066584	0.201824411354994	0.125283794287695	1.35893682937247	0.153870325275913	1.61093789106942	0.148516404142341	0.757922964280616	NA	NA	0.687961072694226	0.455486745226325	83.3881607066276
a8625	loss_cnaOV83	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.21839710447986	2.38256832474147	-0.16417122026161	1.07446020127229	0.837295969699667	0.188129529149865	0.152794137993395	0.196073104616158	0.758027442110371	NA	NA	0.652080747586965	0.759254381162478	83.3899404540437
a8626	NF1_mut	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-3.79228671322814	-4.20636854489819	0.41408183167005	2.49265083709739	2.34637349878609	0.175274266991165	0.16612107299883	0.176477373224799	0.758114914958269	NA	NA	0.928403474304435	0.77137108970418	83.3899404540437
a8627	gain_cnaOV51_(MYC)	333	T0901317	LXR	8	24	2.32630161961136	NA	4.86205373076171	4.71711775829171	0.14493597247	0.726532936081046	1.2230704657178	0.128608727348951	0.199489885829253	0.118501735208641	0.758331399271759	NA	NA	0.00529599853691273	0.689885616407787	83.4040840397763
a8628	loss_cnaOV85	295	NVP-BHG712	EPHB4	7	25	2.32630161961136	NA	3.00967563525933	3.31873691267396	-0.309061277414629	0.987090439899496	1.11169096665235	0.284086359836626	0.31310330332659	0.278010064564354	0.758612774834855	NA	NA	0.0635421187070486	0.491953988377658	83.4086898087385
a8629	loss_cnaOV44	272	AR-42	HDAC	3	27	1.63315443905142	NA	0.51662314003646	0.27048384546738	0.24613929456908	1.73544112211607	1.86718253971743	0.132469537810543	0.141830968179983	0.131823905447578	0.758616004551682	NA	NA	0.488232803174049	0.834444163999627	83.4086898087385
a8630	gain_cnaOV50	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.29230627073265	4.33484338077226	-0.0425371100396088	0.737418875837507	0.573070590737379	0.0718300444126511	0.0576837824924107	0.0742266497830148	0.758740305415308	NA	NA	0.256281104835342	0.917939031222766	83.4086898087385
a8631	loss_cnaOV21, loss_cnaOV22	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.74625499166685	4.57211121380498	0.174143777861875	0.748546808043093	0.963633578494846	0.18315319314922	0.232642469369598	0.180715763489562	0.75886926394834	NA	NA	0.943406821885596	0.736588881607117	83.4086898087385
a8632	gain_cnaOV95_(MECOM)	299	OSI-027	MTORC1/2	9	23	2.99573227355399	NA	1.35541919152307	1.59977875837018	-0.244359566847109	1.09759959562002	2.15600713093972	0.126523531944497	0.222630882721009	0.11333894185248	0.759073661188145	NA	NA	0.783591102952139	0.676599174042654	83.4086898087385
a8633	gain_cnaOV51_(MYC)	308	XL-880	MET	8	24	1.63315443905142	NA	0.102857563137758	0.303178679898652	-0.200321116760893	0.454998124172524	1.08492840092431	0.205446697262943	0.440268005775198	0.184639941760423	0.759196934356836	NA	NA	0.370506890158054	0.470336215956823	83.4086898087385
a8634	loss_cnaOV55	1502	Bicalutamide	ANDR (androgen receptor)	8	24	2.30258509299405	NA	4.48363057918893	4.52701289753241	-0.0433823183434834	0.661778479776873	0.584998018919091	0.0718503199057368	0.0655541388382866	0.0741580602676937	0.759225096897231	NA	NA	0.616702559303077	0.871849955866071	83.4086898087385
a8635	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.68854994852238	4.46816147711537	0.220388471407008	0.649512703105888	0.681055888818595	0.324612651373461	0.339313565928947	0.32359821715852	0.759411315933095	NA	NA	0.0545098180843135	0.624154302782612	83.4086898087385
a8636	gain_cnaOV26	164	JQ12	HDAC	3	16	1.63315443905142	NA	2.08792314380006	1.73876241627776	0.349160727522307	2.62705864846665	2.18324620210928	0.155873375020052	0.132909376700099	0.15992732619206	0.759446069359272	NA	NA	0.663079537869377	0.844678492033046	83.4086898087385
a8637	gain_cnaOV95_(MECOM)	1129	PF-4708671	RPS6KB1 (p70S6KA)	7	25	2.30258509299405	NA	4.41910851392109	4.13484936994565	0.28425914397544	1.05661090797581	0.952628169736575	0.291753437887873	0.269029159011814	0.298394644422539	0.759558245572912	NA	NA	0.049126226270494	0.53674830385331	83.4086898087385
a8638	gain_cnaOV4_(KRAS)	136	Mitomycin C	DNA crosslinker	6	13	2.77258872223978	NA	-0.724797216876057	-0.477178644608698	-0.247618572267359	0.817923838373142	1.70938033118215	0.164737501020343	0.302740378321623	0.14485867641645	0.759711425752982	NA	NA	0.909967087814238	0.674765124535701	83.4086898087385
a8639	gain_cnaOV96	333	T0901317	LXR	5	27	2.32630161961136	NA	5.08010787392786	4.69284135835021	0.387266515577652	0.983669847066036	1.13888587164691	0.345948328219917	0.393695625349035	0.34003979258926	0.759740780971307	NA	NA	0.00529679395813019	0.459902419245922	83.4086898087385
a8640	loss_cnaOV82	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.74109635474051	2.304189845193	0.436906509547515	2.7032827421874	1.44866515948713	0.280004876810543	0.16162072236439	0.301592474069159	0.759743665929478	NA	NA	0.244250250232629	0.807181994074458	83.4086898087385
a8641	loss_cnaOV35	1008	Methotrexate	Dihydrofolate reductase (DHFR)	5	26	-1.6094379124341	NA	0.795129840846932	0.521586214652631	0.273543626194301	1.44588937387368	1.17775982107917	0.22453691733249	0.189187105968869	0.23225756329814	0.759750217598756	NA	NA	0.433136696086139	0.706564662278801	83.4086898087385
a8642	gain_cnaOV18_(CCNE1)	211	TL-2-105	CRAF	4	28	2.32630161961136	1.63315443905142	4.3658837424564	4.41533102813802	-0.0494472856816195	0.666098250314339	0.633675877984252	0.0776261806231942	0.0742342224413362	0.0780324569698207	0.759775984978526	NA	NA	0.273347936796446	0.895944392430081	83.4086898087385
a8643	loss_cnaOV59	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.592596518062785	-0.848448198948989	0.255851680886204	0.723230981204478	0.817861521694508	0.316418679132658	0.353762058782528	0.312830074651404	0.759779787342866	NA	NA	0.0801426689879355	0.550078258774307	83.4086898087385
a8644	gain_cnaOV26	158	PF-562271	FAK	3	15	0.940007258491471	NA	2.01566665812192	2.34419446795807	-0.328527809836155	2.34034681707443	1.21783845306565	0.233333642378128	0.140375694507891	0.269763045344114	0.760449957890922	NA	NA	0.749128801975787	0.832877105373402	83.454639790619
a8645	gain_cnaOV96	152	CP466722	ATM	5	27	2.77258872223978	NA	2.78304824700308	2.62170713649659	0.161341110506497	0.630689606918462	0.843547778901098	0.19714891427256	0.255816979916328	0.191264934295338	0.760484333086088	NA	NA	0.55776614145593	0.635301623189745	83.454639790619
a8646	loss_cnaOV40	277	ABT-869	VEGFR and PDGFR family	7	25	0.0237165266173161	NA	2.8297535630528	2.6841949113339	0.145558651718903	0.858954639855435	0.471969471643587	0.255026888823606	0.169460231035484	0.308406921346013	0.760675212571349	NA	NA	0.137381201892037	0.679681258136594	83.454639790619
a8647	RB1_mut	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	3.70115404449077	3.85539834718248	-0.154244302691714	1.40119866749247	0.821347133365167	0.177192127992286	0.110080252194175	0.187794291141864	0.760700540382689	NA	NA	0.924090492461404	0.867579369482742	83.454639790619
a8648	loss_cnaOV1	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	4.79318853588737	4.50682813914573	0.286360396741641	0.285425391227479	1.05504475651087	0.280215043955533	1.00327583159347	0.271420141159379	0.760719480350196	NA	NA	0.193388070605068	0.288988933945576	83.454639790619
a8649	loss_cnaOV81_(RB1)	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.26161572014558	4.41624102594494	-0.154625305799363	1.01212919190317	0.848846414072646	0.178552286286153	0.152772301240133	0.182159343829342	0.76072608353572	NA	NA	0.870108637782225	0.786497048401029	83.454639790619
a8650	loss_cnaOV55	1023	GW 441756	NTRK1	7	24	0.693147180559945	NA	2.15083024538072	2.34152983459162	-0.190699589210893	1.45107526771812	1.21130897096965	0.150792280135552	0.131419502112235	0.157432656556847	0.761036851031701	NA	NA	0.845265697070733	0.758822927226897	83.4790803291876
a8651	PIK3R1_mut	177	GSK-650394	SGK3	3	16	2.77258872223978	NA	4.29375268669124	3.88950036321737	0.40425232347387	1.01741632405062	1.62448928349213	0.258252599294712	0.397332256145083	0.248848870584642	0.761451632548357	NA	NA	0.745191042724158	0.599966754399518	83.5069256734499
a8652	loss_cnaOV87, loss_cnaOV88	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.34560492304702	2.14760535698447	0.197999566062553	0.971164240392874	1.33347731413042	0.150948006361412	0.203878559184237	0.148483640452235	0.761535456353905	NA	NA	0.68797662212494	0.769331398710356	83.5069256734499
a8653	loss_cnaOV35	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	1.14874666377251	0.789429024463467	0.359317639309048	0.94634210162573	1.39993324107793	0.266161905321253	0.37969106382541	0.256667695834108	0.761554734508735	NA	NA	0.165175709934412	0.49320798563818	83.5069256734499
a8654	gain_cnaOV4_(KRAS)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	8	24	1.63315443905142	NA	2.79364317637546	2.887142046227	-0.0934988698515418	0.87059099806663	0.78910188569106	0.115594724787885	0.107397009685581	0.118487702978507	0.761718217162016	NA	NA	0.0200161837707909	0.79275698029902	83.5152004830153
a8655	loss_cnaOV87, loss_cnaOV88	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.982668576208	2.84651300223794	0.136155573970065	1.52875032053373	1.09469683777678	0.12061567262928	0.0890633167112136	0.12437742512035	0.761852117165506	NA	NA	0.392986922283599	0.893085488278359	83.5185966828242
a8656	gain_cnaOV94	1030	KU-55933	ATM	7	26	2.30258509299405	NA	4.30449133240513	4.10966874040297	0.19482259200216	1.16167744254501	1.00217802641936	0.188240023569244	0.167707992655294	0.194399185440368	0.761925238500155	NA	NA	0.531552652491363	0.695414879476064	83.5185966828242
a8657	PIK3R1_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	0.686360226386742	0.903121617978632	-0.21676139159189	0.535121872736951	1.33053640903068	0.172858819030545	0.405069205045265	0.162912784739055	0.762241077630664	NA	NA	0.845616464302687	0.545359564194686	83.5395500842612
a8658	loss_cnaOV40	309	Y-39983	ROCK	7	25	2.99573227355399	NA	5.16441465677169	4.90825457924686	0.256160077524831	1.51335781907892	1.1652495776367	0.206132382694533	0.169266034969006	0.219832800149443	0.76229248237805	NA	NA	0.374824625793765	0.689101654235758	83.5395500842612
a8659	KRAS_mut	290	KIN001-260	IKK	6	25	2.99573227355399	NA	4.70806769089712	4.88436931646817	-0.176301625571051	0.755566792252022	0.935101367038584	0.19444597249746	0.233336916575662	0.18853744822274	0.762534835136627	NA	NA	0.666895579324615	0.636593192821135	83.5526266697299
a8660	loss_cnaOV21, loss_cnaOV22	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.02757774535881	5.06556598130935	-0.0379882359505403	0.3682035857696	0.636850362087033	0.0610196231796248	0.103171825095455	0.0596501756331714	0.762592818713172	NA	NA	0.112198509627426	0.884712211992167	83.5526266697299
a8661	loss_cnaOV82	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.83295825777916	-0.813557595376299	-0.0194006624028606	1.06089199952533	0.792010434604623	0.0238509512792989	0.0182871229225416	0.024495463134328	0.762911413815241	NA	NA	0.0801556438214778	0.977973837652325	83.5526266697299
a8662	BRCA1_mut	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-3.82719630941535	-4.09422872493177	0.267032415516423	2.59474297154671	1.36022612316307	0.173996685854914	0.102912858207781	0.196314723683931	0.762930004587361	NA	NA	0.864745771866726	0.852086773207203	83.5526266697299
a8663	loss_cnaOV83	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.83142588287486	3.65367885606622	0.177747026808634	0.919820535381205	1.07946331488637	0.167754201961236	0.193240985574398	0.16466240617667	0.762937178133118	NA	NA	0.831771130227175	0.712527405638872	83.5526266697299
a8664	NF1_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.2005091375163	4.1965341891437	0.00397494837259948	1.04809639365619	0.974202225584856	0.00404846058634189	0.00379254083561269	0.00408020867557878	0.762947454477759	NA	NA	0.0491362762053685	0.994651759817402	83.5526266697299
a8665	loss_cnaOV57_(ZNRF3)	341	EX-527	SIRT1	4	27	2.99573227355399	NA	5.91359400324678	5.75253091231841	0.161063090928363	0.591882090485624	0.563643536722561	0.284247360811754	0.272120230561825	0.285753460183191	0.763028215856006	NA	NA	0.112344630553981	0.637240762080098	83.5526266697299
a8666	gain_cnaOV51_(MYC)	1230	IOX2	EGLN1	8	24	-2.30258509299405	NA	-0.196869682423512	-0.0188669871046563	-0.178002695318856	1.04477154221577	0.944870726111075	0.183677885270755	0.170374754792177	0.188388411662921	0.76337394158782	NA	NA	0.550826117318893	0.677435383826774	83.5580484534133
a8667	loss_cnaOV39	151	QS11	ARFGAP	5	14	2.32630161961136	NA	4.13478492853135	3.63534895767402	0.499435970857334	1.9150913893645	1.28809768053769	0.342066956068339	0.260789627915911	0.387731441802499	0.763627763529459	NA	NA	0.066736689095079	0.610209441398954	83.5580484534133
a8668	loss_cnaOV41	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	3.72687089551299	3.91537296572021	-0.188502070207224	1.50251934558095	1.61797814105738	0.117626515982567	0.125457333219453	0.116504707587727	0.763692849104413	NA	NA	0.71693509305619	0.808308673178739	83.5580484534133
a8669	loss_cnaOV81_(RB1)	219	AT-7519	CDK9	4	28	2.32630161961136	NA	1.37310806900599	1.51550765421171	-0.142399585205724	1.1657156271322	1.7688259701718	0.0828835219583269	0.122156366348149	0.0805051416063805	0.76370208248253	NA	NA	0.318379613463292	0.840165553415036	83.5580484534133
a8670	gain_cnaOV50	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.594515028060014	-0.848163975245696	0.253648947185682	0.873922975012056	0.8007978994856	0.313662159793284	0.290241765508205	0.316745270371733	0.763812726696184	NA	NA	0.0801593428307971	0.614742813617579	83.5580484534133
a8671	loss_cnaOV55	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	1.91621430941811	2.19874566545866	-0.282531356040548	0.945047545169562	1.6608662648786	0.181270237722062	0.298959938560398	0.170110840357877	0.763815935647834	NA	NA	0.948165218180652	0.668724996402807	83.5580484534133
a8672	gain_cnaOV4_(KRAS)	257	NPK76-II-72-1	PLK3	8	24	2.32630161961136	NA	3.34619078249235	3.19086898168988	0.155321800802464	1.42415244713453	1.17715971835824	0.125340126868731	0.109062622554895	0.131946241771752	0.763828428526164	NA	NA	0.602646902797541	0.786169482737803	83.5580484534133
a8673	loss_cnaOV102	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.66375893216851	5.72038181119669	-0.0566228790281853	0.665563519547573	0.465699856569568	0.117569628754548	0.0850750940596557	0.121586636176528	0.764023237250221	NA	NA	0.383958921777058	0.897758482930862	83.5580484534133
a8674	loss_cnaOV20	170	Shikonin	unknown	3	15	2.77258872223978	NA	0.0811087567529711	-0.0297589924993848	0.110867749252356	0.337644468845671	0.84755056569255	0.138282557057194	0.328356479913287	0.130809598553879	0.764067172324723	NA	NA	0.587628339493139	0.714672333148835	83.5580484534133
a8675	loss_cnaOV43_(NF1)	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.65872234197302	4.45694459595893	0.201777746014082	0.837510735171963	0.648768484331534	0.297636605200155	0.240925563745344	0.311016565827772	0.764123436632351	NA	NA	0.0545252294647697	0.631838912334654	83.5580484534133
a8676	gain_cnaOV51_(MYC)	1039	SL 0101-1	RSK, AURKB, PIM3	8	25	2.30258509299405	NA	4.8576982373447	4.96325178876932	-0.105553551424624	0.991436437940348	0.768610648351276	0.128066534065517	0.106465273400587	0.137330326675858	0.764231932244489	NA	NA	0.94622511847504	0.788422148061109	83.5580484534133
a8677	SMARCA4_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.95604119143685	2.78204873834172	0.173992453095131	0.562093420890118	0.990543126907821	0.179626046367447	0.309543657030536	0.175653586773434	0.764285677682389	NA	NA	0.966348991357012	0.667864177894274	83.5580484534133
a8678	loss_cnaOV57_(ZNRF3)	1199	Tamoxifen	ER	4	28	1.6094379124341	NA	3.90945466155147	3.98990111487863	-0.0804464533271543	1.319124263267	0.678867896609064	0.104840425841147	0.060984742353171	0.118500894988529	0.764497500521743	NA	NA	0.527536505240403	0.911762514564588	83.5580484534133
a8679	gain_cnaOV51_(MYC)	1023	GW 441756	NTRK1	8	23	0.693147180559945	NA	2.16402597937644	2.3452313005588	-0.181205321182352	1.4236247822668	1.2097360521277	0.143281477972767	0.12728446669341	0.149789138600644	0.764561672139628	NA	NA	0.845273442648814	0.753736764731814	83.5580484534133
a8680	loss_cnaOV16, loss_cnaOV17	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	25	2.30258509299405	NA	2.26827347193407	2.14240495732407	0.125868514610008	1.29075512423599	1.31649809791949	0.0959293714159265	0.0975154095820544	0.0956085806800045	0.764606324389506	NA	NA	0.687989632792714	0.836344428743078	83.5580484534133
a8681	loss_cnaOV36	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.12032811629338	3.32128047596811	-0.200952359674738	0.702904497801163	1.13819941303074	0.180310130567769	0.285888567086085	0.176552858290141	0.764724719376953	NA	NA	0.951159304238066	0.688386615710903	83.5580484534133
a8682	gain_cnaOV94	1129	PF-4708671	RPS6KB1 (p70S6KA)	7	25	2.30258509299405	NA	4.41701574976213	4.13543534391016	0.281580405851973	1.05803380633868	0.952414605723935	0.288962026061675	0.266135547054382	0.295648979089251	0.764747243581529	NA	NA	0.0491415483897943	0.540944104154456	83.5580484534133
a8683	gain_cnaOV50	309	Y-39983	ROCK	4	28	2.99573227355399	NA	4.86489605531108	4.97848867347604	-0.113592618164955	1.67563348592247	1.18976053204306	0.0911002493732762	0.0677908499199157	0.0954751944661447	0.764857320828194	NA	NA	0.374841344883546	0.903096689904314	83.5580484534133
a8684	loss_cnaOV43_(NF1)	1218	JQ1	BRD2, BRD3, BRD4	5	26	0	NA	2.36666663607692	2.2800083553207	0.0866582807562168	1.79427328871289	0.663768279883164	0.0954727447742049	0.0482971469849949	0.130555019549097	0.764895325258675	NA	NA	0.596210633916243	0.919989800599269	83.5580484534133
a8685	loss_cnaOV34	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	5.865448622905	5.96182490643296	-0.0963762835279587	0.954742754879025	0.662935035771678	0.136243161760384	0.100944765525003	0.145378171808002	0.765043859362713	NA	NA	0.909116619266131	0.837589072221715	83.5580484534133
a8686	TP53_mut	208	SB-715992	KIF11	22	10	-2.05572501506252	NA	-1.27259288469648	-1.41597262981347	0.143379745116992	2.04980885025736	1.43292318996869	0.0760212061328983	0.0699478612842317	0.100061012426022	0.765059022243964	NA	NA	0.0754419771493587	0.821729732524387	83.5580484534133
a8687	loss_cnaOV81_(RB1)	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	0.130050026799868	-0.137169227482008	0.267219254281877	1.72605656752257	1.2270037498389	0.210783284814134	0.154814888057475	0.217781937762587	0.765082739724268	NA	NA	0.768249878835165	0.816206503485652	83.5580484534133
a8688	loss_cnaOV54	306	TG101348	JAK2	10	22	2.32630161961136	NA	2.97943536082793	2.75343282616013	0.226002534667797	1.3777083056081	1.41548147978006	0.160941095891494	0.164042369308387	0.159664776894794	0.765133968985243	NA	NA	0.629085888708763	0.67486441967877	83.5580484534133
a8689	loss_cnaOV1	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	2.01464565837137	1.51880366573917	0.495841992632197	0.0191983919920057	1.68496160119586	0.304602100706567	25.8272668272774	0.29427495100202	0.765243421174324	NA	NA	0.0801852157370651	0.124459524864391	83.5580484534133
a8690	loss_cnaOV81_(RB1)	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.29465323395763	4.33449568251671	-0.0398424485590834	0.50506790061251	0.601456880639558	0.0672771619578721	0.0788853310827421	0.066243233457928	0.765279338391511	NA	NA	0.256324996554225	0.892329411682454	83.5580484534133
a8691	loss_cnaOV34	1373	Dabrafenib	BRAF	5	27	2.30258509299405	NA	3.94375321040187	3.59121039479524	0.352542815606633	1.27126283168246	2.13346289304193	0.172843005149103	0.277317016450532	0.165244409338646	0.765668391825575	NA	NA	0.748569274801297	0.627387498763405	83.5882963283227
a8692	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	258	STF-62247	stimulates autophagy	7	24	2.32630161961136	NA	4.41499983847815	4.5112155139771	-0.0962156754989509	0.825596477541545	0.637901488047908	0.141287393770463	0.116540801852088	0.150831558323195	0.765732560732152	NA	NA	0.0545304144050717	0.783032029671326	83.5882963283227
a8693	gain_cnaOV96	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.62982340158353	3.5285484636476	0.101274937935929	0.4043830642872	0.965422723810259	0.111192337354727	0.250443074599192	0.104902169213735	0.765826179843816	NA	NA	0.664778495906509	0.701797299666998	83.5888991418129
a8694	loss_cnaOV59	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	1.16862333258646	0.799077678396337	0.369545654190127	0.893108020923562	1.39093973327812	0.273574388322377	0.41377486880924	0.26568056497976	0.766002284236356	NA	NA	0.165200018579066	0.50420620089899	83.5985039387121
a8695	SMAD4_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.86323134658424	2.86382277519652	-0.000591428612271461	1.08011853028942	0.787090507626396	0.000730221236582196	0.000547558990690574	0.000751411186567366	0.766196304912494	NA	NA	0.0200231768333965	0.999339456161122	83.6032226090482
a8696	loss_cnaOV21, loss_cnaOV22	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.36876428004288	5.17238918757004	0.196375092472844	0.483887153980326	0.792189385503334	0.253237329998372	0.405828282188348	0.247889073075718	0.766362449861892	NA	NA	0.335889458829579	0.574949602513951	83.6032226090482
a8697	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.74102455098378	4.57265229387564	0.168372257108135	2.09492475255423	0.809521697411147	0.177065536446744	0.0803715058991252	0.207989801442741	0.766386025553403	NA	NA	0.943412724139131	0.902440176618469	83.6032226090482
a8698	loss_cnaOV36	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.84379115780728	4.86174726933486	-0.0179561115275719	0.821490096616996	0.609076819677872	0.0287074581006026	0.0218579768660846	0.0294808650525701	0.766397968707302	NA	NA	0.050685357483699	0.973654588368953	83.6032226090482
a8699	loss_cnaOV82	308	XL-880	MET	3	29	1.63315443905142	NA	0.0331781893537458	0.275848767400292	-0.242670578046547	0.334539335218136	1.0067379842468	0.248528543804273	0.725387278863078	0.241046411125635	0.766517541295177	NA	NA	0.370554850249862	0.396395237095104	83.6066541241015
a8700	loss_cnaOV43_(NF1)	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.89130880245849	4.77724882739421	0.114059975064285	0.835144039018218	0.638827647965039	0.170660764904882	0.136575213059501	0.178545771191368	0.7666681751106	NA	NA	0.763197287611979	0.783617568219128	83.6134724137565
a8701	ARID1A_mut	333	T0901317	LXR	8	24	2.32630161961136	NA	4.07938474095644	4.97800742156014	-0.898622680603702	1.68248917721447	0.768006895039423	0.85189198073493	0.534103097228515	1.17007111056936	0.766924398679683	NA	NA	0.00530076839067132	0.182229491541644	83.6238506494773
a8702	gain_cnaOV51_(MYC)	1021	Axitinib	PDGFR, KIT, VEGFR	7	23	0.693147180559945	NA	2.53742126463929	2.52158425846592	0.0158370061733653	0.979639164491479	1.06548930645448	0.0151161873121683	0.0161661627540035	0.0148635993598701	0.766939602603844	NA	NA	0.197922833151288	0.971417430302693	83.6238506494773
a8703	gain_cnaOV4_(KRAS)	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	0.0307476491608399	-0.0897199477610292	0.120467596921869	0.923462668774249	0.982531465001408	0.12406483023433	0.130452048572544	0.122609403579453	0.767140293666742	NA	NA	0.550846585723475	0.76967105466011	83.6269626735754
a8704	loss_cnaOV34	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.40635642882556	1.51462460925275	-0.10826818042719	1.28076609879629	1.77604654498503	0.0630097196901546	0.084533921165578	0.060960215672784	0.767266383815	NA	NA	0.318402858294208	0.875507125676705	83.6269626735754
a8705	loss_cnaOV34	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	4.53694578409392	4.79846026443123	-0.261514480337314	1.40057071198275	1.20573369794115	0.211849118254884	0.186719940735513	0.216892404005846	0.767337775079138	NA	NA	0.427148389453071	0.711564879110687	83.6269626735754
a8706	gain_cnaOV48_(SOX17)	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.44677881612827	5.54825962456226	-0.101480808433989	0.609655909395967	1.00969211720642	0.10270560168219	0.16645587596212	0.100506685854657	0.76743515295719	NA	NA	0.306470049658167	0.814283505512813	83.6269626735754
a8707	loss_cnaOV70	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	4.08909392938202	3.90172505938193	0.187368870000094	1.24141067203232	1.22955860600701	0.152285409794071	0.15093222107826	0.152387099797197	0.767524342321912	NA	NA	0.700175953020745	0.823016645956903	83.6269626735754
a8708	loss_cnaOV58	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	2.28331733415412	2.28430669683121	-0.00098936267708849	2.16760788866065	1.74511894787031	0.000548063124022064	0.000456430649779472	0.000566931370664376	0.767587306837962	NA	NA	0.112138891485746	0.99926665018805	83.6269626735754
a8709	loss_cnaOV39	207	AS601245	JNK 	5	13	2.07944154167984	NA	2.04596557944769	1.97328015744639	0.0726854220012934	1.18335465496587	0.934204872209368	0.0725175165270879	0.0614231935424209	0.0778045845868845	0.767614443249728	NA	NA	0.483424422587603	0.905833464021229	83.6269626735754
a8710	loss_cnaOV102	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.39835441624387	2.52245378315634	-0.124099366912471	0.492076249928691	0.642414916774055	0.195893804858029	0.252195400469855	0.193176347049423	0.767774361229961	NA	NA	0.858778843142364	0.716261668849014	83.6269626735754
a8711	loss_cnaOV43_(NF1)	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	3.07134109027697	2.73654895591717	0.334792134359796	0.247659298324514	1.3203630550009	0.271633709829643	1.35182541751818	0.253560665069933	0.767795709844682	NA	NA	0.0963030320865783	0.236617889397501	83.6269626735754
a8712	loss_cnaOV33_(ZFHX3)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	4	28	2.30258509299405	NA	1.06367394555377	0.84147817982649	0.222195765727278	2.59583553294202	0.999708524000838	0.177144797370001	0.085597012178753	0.222260549342972	0.767849513882626	NA	NA	0.845628204021953	0.875841682457355	83.6269626735754
a8713	loss_cnaOV39	1058	GDC0941	PI3K (class 1)	10	23	1.38629436111989	0.693147180559945	1.08377783959247	0.739563809039778	0.344214030552697	1.19155245209586	1.40520096574383	0.255603783958685	0.288878622126326	0.244957154844033	0.768342986528666	NA	NA	0.165212606436002	0.479101712440584	83.6711029617771
a8714	loss_cnaOV35	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	3.73103570958315	3.91457203993749	-0.183536330354345	1.4911246042877	1.61975956451129	0.11452190570646	0.12308584395066	0.113310848335519	0.768497006448673	NA	NA	0.716953487355781	0.812089439181933	83.6782715991795
a8715	gain_cnaOV18_(CCNE1)	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	2.49457321430488	2.2881694053711	0.206403808933789	1.01306235989812	1.49547977818429	0.141911310339318	0.203742451703117	0.138018455310971	0.768684484112608	NA	NA	0.821789904472291	0.736194970959494	83.6810011329763
a8716	loss_cnaOV81_(RB1)	290	KIN001-260	IKK	4	27	2.99573227355399	NA	4.75172111782882	4.86484276243599	-0.113121644607169	0.931620954790802	0.906014504619062	0.124487761928411	0.12142453862319	0.124856328491928	0.768698462247394	NA	NA	0.666922887768492	0.831532760607562	83.6810011329763
a8717	loss_cnaOV70	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	3	29	2.32630161961136	NA	5.15141954937003	5.14151011792784	0.00990943144219258	0.487268740633862	0.598358196599476	0.0167501777267707	0.0203366861360775	0.0165610356781419	0.768883898052974	NA	NA	0.0122585720172686	0.976158396779668	83.683746580738
a8718	loss_cnaOV84	1022	AZD7762	CHEK1, CHEK2	6	25	0.693147180559945	NA	-0.786691374813729	-0.822333567799659	0.0356421929859305	0.67070388756225	0.839970544310686	0.0438239576479656	0.0531414736769697	0.042432670082711	0.768900075773205	NA	NA	0.0801799270527097	0.914037435297561	83.683746580738
a8719	loss_cnaOV16, loss_cnaOV17	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	1.6094379124341	NA	1.11539256246768	1.38307183046003	-0.267679267992344	1.70845891350387	1.29514281797394	0.196874749958046	0.156678785703638	0.206679343990101	0.7690557466272	NA	NA	0.582726751672964	0.753232761568673	83.6863684792233
a8720	gain_cnaOV48_(SOX17)	290	KIN001-260	IKK	3	28	2.99573227355399	NA	5.02652478887115	4.8313594532312	0.195165335639951	0.682445537237438	0.922076550042591	0.215038359659132	0.285979356579848	0.211658495849326	0.769153471625542	NA	NA	0.666924871777727	0.68278613853851	83.6863684792233
a8721	gain_cnaOV18_(CCNE1)	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-2.99799299868401	-2.68040435146321	-0.317588647220802	0.679400712560361	1.32508297136906	0.256969759017393	0.467454097926908	0.239674536676501	0.76933228825331	NA	NA	0.38297900464166	0.524992596770844	83.6863684792233
a8722	gain_cnaOV95_(MECOM)	326	GSK690693	AKT	9	23	2.32630161961136	NA	4.28904078072652	4.09827955358481	0.190761227141706	1.36075207983091	1.50418509627784	0.130007635875493	0.140188084199298	0.126820314610051	0.769339456679122	NA	NA	0.0950774265699844	0.733872453248488	83.6863684792233
a8723	gain_cnaOV94	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	7	25	0.246860077931526	2.32630161961136	0.822532647245667	1.05503837653394	-0.232505729288275	1.13033735449774	1.64871506697855	0.14914814925007	0.205695873327647	0.141022384003785	0.769407228079804	NA	NA	0.791989910758975	0.673141750003512	83.6863684792233
a8724	loss_cnaOV16, loss_cnaOV17	211	TL-2-105	CRAF	6	26	2.32630161961136	1.63315443905142	4.52422529656884	4.38259430685681	0.141630989712035	0.563061502834364	0.64802332990834	0.223162745754671	0.251537334730019	0.218558473399512	0.769580747162067	NA	NA	0.273411339100123	0.603786544369912	83.6863684792233
a8725	loss_cnaOV36	1262	UNC1215	LMBL3	3	30	0	NA	2.91715606587955	2.76673836840552	0.150417697474031	0.984624936959265	0.44381862269188	0.30277058635126	0.152766491917779	0.338917048053792	0.769648172008719	NA	NA	0.111304052650396	0.817010936160728	83.6863684792233
a8726	gain_cnaOV50	1010	Gefitinib	EGFR	4	26	-0.693147180559945	NA	0.753336952593505	0.951901244028393	-0.198564291434889	0.976883111923898	1.31044826608175	0.155264522868076	0.203263101809418	0.15152394533559	0.769731988365732	NA	NA	0.957693564027071	0.734166155650654	83.6863684792233
a8727	loss_cnaOV33_(ZFHX3)	225	Genentech Cpd 10	AURKA, AURKB	4	28	2.32630161961136	NA	3.21860195092736	2.79065973021398	0.427942220713378	1.79367498043762	1.87005411601174	0.229760584726677	0.238584038569222	0.2288394849375	0.769776895427458	NA	NA	0.348625809710406	0.680078281951828	83.6863684792233
a8728	loss_cnaOV57_(ZNRF3)	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.55692304936254	1.58197647335996	-0.0250534239974134	1.57926480322157	1.21324013313112	0.0196961758330278	0.0158639792049481	0.0206500125682091	0.769906231919347	NA	NA	0.166731412626383	0.977639960649547	83.6863684792233
a8729	SMARCA4_mut	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.74949211875909	3.53554073481326	0.21395138394583	1.45587334271608	0.920692620511344	0.221563489639854	0.146957415640761	0.232380904527076	0.770003994224835	NA	NA	0.729728320117385	0.82468794152448	83.6863684792233
a8730	loss_cnaOV16, loss_cnaOV17	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	2.9189503037778	2.37416442953096	0.544785874246838	2.35761330753936	1.4791964741105	0.342839221108665	0.231075160843672	0.368298521380968	0.77021621024373	NA	NA	0.230803356548311	0.731398105439377	83.6863684792233
a8731	KRAS_mut	306	TG101348	JAK2	7	25	2.32630161961136	NA	2.89989894817209	2.8028233258639	0.0970756223081932	1.13668252406656	1.46778464690455	0.0689551664501748	0.0854025818580356	0.066137510371783	0.770246540453744	NA	NA	0.629109580538834	0.855059842146116	83.6863684792233
a8732	gain_cnaOV49	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.96182787252061	-2.13975064726538	0.177922774744771	0.521234792213507	1.3399281052313	0.136576971976316	0.341348615638633	0.132785314413611	0.770267347718708	NA	NA	0.609216739855003	0.66442145447309	83.6863684792233
a8733	loss_cnaOV102	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.48447013807761	2.27853990477254	0.205930233305078	1.79718393828479	1.21721213311221	0.162691583990265	0.114584950888007	0.169181876932617	0.770368180143177	NA	NA	0.845285920072051	0.862792406060576	83.6863684792233
a8734	MLL2_mut	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	3.1985128087653	2.82041609902207	0.378096709743235	0.031171978100692	1.11296411757465	0.351634258392039	12.1293781396196	0.33972048493996	0.770483936570213	NA	NA	0.309116540317873	0.0789152145271044	83.6863684792233
a8735	loss_cnaOV36	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.39961326799277	2.52232355711336	-0.122710289120584	0.322450776828751	0.650076233525761	0.193693615006278	0.38055510465014	0.188762921626978	0.770490785035268	NA	NA	0.858783954496282	0.609786808649584	83.6863684792233
a8736	gain_cnaOV51_(MYC)	184	BMS-754807	IGF1R	5	12	0.940007258491471	NA	0.830268529112932	0.792053960721431	0.0382145683915006	0.326425199045157	1.25417697187666	0.0351508035502171	0.117069909134724	0.0304698373901086	0.770511759119512	NA	NA	0.360032113224739	0.923419186013557	83.6863684792233
a8737	loss_cnaOV43_(NF1)	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.4462455846604	4.30687570924922	0.139369875411183	0.549934049436908	0.596159569995478	0.236220529624688	0.253430162314713	0.233779481913274	0.770936428114769	NA	NA	0.256361879138377	0.627185340322043	83.7131344540426
a8738	gain_cnaOV4_(KRAS)	208	SB-715992	KIF11	8	24	-2.05572501506252	NA	-1.48049911354606	-1.26303236887869	-0.217466744667367	1.88129674347941	1.88585241204614	0.115379802331451	0.115594068517425	0.115314827013116	0.771074450433932	NA	NA	0.0754645076341327	0.781993426233054	83.7131344540426
a8739	gain_cnaOV96	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.53791720734298	3.56445278437856	-0.0265355770355864	0.783676310737204	0.938400095943591	0.028700788882142	0.0338603791795421	0.028277466243121	0.771083682956059	NA	NA	0.144719489517338	0.953439473630988	83.7131344540426
a8740	loss_cnaOV102	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.35788083987967	4.27591730300902	0.0819635368706582	0.461662100510864	0.846390487389154	0.0992735384551106	0.177540102988656	0.0968389154791775	0.771111108346869	NA	NA	0.319262056028565	0.806184575762101	83.7131344540426
a8741	PIK3CA_mut	1219	PFI-1	BRD2, BRD3, BRD4	7	25	2.30258509299405	NA	2.52334648056487	2.31629272300529	0.207053757559573	0.88797144751895	0.869714499656295	0.23706733018263	0.233176143374987	0.23807095045719	0.771611781454339	NA	NA	0.609655378660263	0.596526683429057	83.7398338063975
a8742	gain_cnaOV95_(MECOM)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	8	23	2.30258509299405	NA	4.58468059707032	4.4862679969781	0.0984126000922236	0.542046128289363	1.02142810935546	0.105973191972845	0.181557610978244	0.0963480436761468	0.77163638631505	NA	NA	0.530485388405032	0.734280832967503	83.7398338063975
a8743	loss_cnaOV35	208	SB-715992	KIF11	5	27	-2.05572501506252	NA	-0.879087525949989	-1.3985678567299	0.519480330779908	2.05652531829774	1.8480877903314	0.276728951025169	0.252600989716918	0.28109072171661	0.772126342232026	NA	NA	0.0754683808037215	0.619750050773762	83.7398338063975
a8744	KRAS_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.63033715031079	3.44856569634353	0.181771453967261	1.0363673278684	1.14160929659347	0.162202344390128	0.175392883468383	0.159223873272285	0.772185686938634	NA	NA	0.728116368608787	0.697912572170281	83.7398338063975
a8745	loss_cnaOV85	151	QS11	ARFGAP	6	13	2.32630161961136	NA	4.10988556206514	3.6084228213617	0.501462740703438	1.59678563913253	1.3957634641577	0.343993509693147	0.314045121908701	0.3592748725559	0.772271942699687	NA	NA	0.0667894686441262	0.52547649474022	83.7398338063975
a8746	loss_cnaOV35	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.32779177752252	3.52072991833875	-0.192938140816232	0.861866801072151	1.15708758117474	0.1721126190227	0.223860741098531	0.166744630186378	0.772599421370877	NA	NA	0.728117850019261	0.67897174327431	83.7398338063975
a8747	loss_cnaOV55	281	CH5424802	ALK	7	25	1.63315443905142	NA	3.85907094480906	3.94679537442723	-0.0877244296181621	0.94513378747714	0.671844981352959	0.119404794669647	0.0928169437813944	0.130572426754611	0.772652338914504	NA	NA	0.956003608630818	0.824138022500325	83.7398338063975
a8748	loss_cnaOV84	306	TG101348	JAK2	6	26	2.32630161961136	NA	2.72030206030302	2.84800243930708	-0.127700379004055	0.644112419101131	1.51466588544623	0.0907300106422375	0.19825790532383	0.0843092725802259	0.772822858890361	NA	NA	0.629121298218571	0.750953195791977	83.7398338063975
a8749	gain_cnaOV50	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	2.97472320658622	3.29061640847569	-0.31589320188947	1.31973838848515	1.06204954443429	0.289660956017742	0.239360470715765	0.297437349834496	0.772846794840341	NA	NA	0.0635907620496155	0.673369994326962	83.7398338063975
a8750	loss_cnaOV35	1007	Docetaxel	Microtubules	5	26	-4.38202663467388	NA	-4.31623339663268	-4.7124868294855	0.396253432852824	1.89202684625072	1.33536162317077	0.27804731558489	0.209433303569687	0.296738670617127	0.772998760051891	NA	NA	0.137342791461032	0.67408623994584	83.7398338063975
a8751	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1016	Temsirolimus	MTOR	8	23	-1.6094379124341	NA	-2.1034680889945	-2.00358050898557	-0.0998875800089358	2.11440879146138	1.35648363570433	0.0634922163929838	0.0472413756565485	0.0736371434050296	0.773114585955799	NA	NA	0.0387488604480183	0.903265988657304	83.7398338063975
a8752	loss_cnaOV57_(ZNRF3)	222	BX-912	PDPK1 (PDK1)	4	28	2.32630161961136	NA	3.6571878877757	3.37459280713794	0.282595080637759	1.49319026085746	1.19450014804639	0.230193061267276	0.189255909341037	0.23658019724815	0.773122250102739	NA	NA	0.329073198909675	0.737529829669434	83.7398338063975
a8753	loss_cnaOV20	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.46570268578311	2.28587121402573	0.179831471757377	0.965695544623477	1.51588645554876	0.123629362308102	0.186219634913499	0.118631228017851	0.773259817383735	NA	NA	0.821800599851432	0.738719238325245	83.7398338063975
a8754	loss_cnaOV21, loss_cnaOV22	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	2.55371780546806	1.9889565828087	0.564761222659361	2.25079392558107	1.97753565583914	0.282816638080742	0.250916450520259	0.285588389262045	0.773366988469408	NA	NA	0.134267521198784	0.711222041249196	83.7398338063975
a8755	loss_cnaOV39	262	VX-11e	ERK	9	23	1.63315443905142	NA	2.7032575250645	2.92032891599755	-0.217071390933056	1.12833889489617	1.12388676521398	0.192939360973151	0.192381377540859	0.193143471078892	0.773367047241063	NA	NA	0.393059946403543	0.63151722104597	83.7398338063975
a8756	gain_cnaOV95_(MECOM)	295	NVP-BHG712	EPHB4	9	23	2.32630161961136	NA	3.32216570756176	3.22333308241776	0.0988326251439982	1.0653966096605	1.10546723716816	0.0902642767322723	0.0927660405973062	0.0894034864363544	0.773403843688235	NA	NA	0.0635925990123324	0.818541089866345	83.7398338063975
a8757	gain_cnaOV19	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.29072110184792	3.984844487813	0.305876614034914	0.844984817692389	1.06820269695781	0.289987570026955	0.361990662589948	0.286346977877922	0.773554821834567	NA	NA	0.106318124607509	0.606097695752707	83.7398338063975
a8758	loss_cnaOV35	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.11963709197656	1.90595663479811	0.213680457178452	0.766405311930043	1.41931644604271	0.158208849752016	0.278808684976803	0.150551667159377	0.773638755671887	NA	NA	0.839823592822175	0.636309751733653	83.7398338063975
a8759	loss_cnaOV36	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.61408342447858	8.76409954071057	-0.150016116231988	0.783566584830207	1.27230825324194	0.12051636047625	0.191452927085317	0.117908624619652	0.773709977864305	NA	NA	0.531992206263338	0.787272176369495	83.7398338063975
a8760	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.91328371519224	1.52726970228563	0.386014012906607	1.60976759846411	1.22276688616628	0.305213015841904	0.239794870560761	0.315688965144346	0.773772235811174	NA	NA	0.166761768212116	0.723524335036808	83.7398338063975
a8761	SMAD4_mut	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.11862164869277	5.19826601150281	-0.0796443628100345	0.523094907870184	0.792384007195171	0.102457677297988	0.152256046869796	0.100512329990044	0.773823107905481	NA	NA	0.335937034862137	0.827633410807857	83.7398338063975
a8762	TP53_mut	229	LY317615	PRKCB (PKCbeta)	22	10	2.99573227355399	2.32630161961136	2.79707938658224	2.64328539400198	0.153793992580253	1.77869798474901	1.47079662517163	0.0908829642444313	0.0864643654509759	0.104565097545221	0.773888681195803	NA	NA	0.323637280062299	0.800234617544228	83.7398338063975
a8763	gain_cnaOV4_(KRAS)	238	CAL-101	PI3Kdelta	8	24	2.99573227355399	2.32630161961136	4.4761388490443	4.357583152494	0.118555696550303	0.816904434351926	1.03963636065053	0.119493949185092	0.145127987515891	0.11403573502962	0.773923393034216	NA	NA	0.513529332042527	0.745305526347937	83.7398338063975
a8764	gain_cnaOV26	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.55433548566933	3.24741732344619	0.306918162223141	1.01006448522955	1.04829537358196	0.293479689213323	0.303859968062721	0.292778323703195	0.77399215154302	NA	NA	0.0934496714209467	0.658645597880401	83.7398338063975
a8765	loss_cnaOV21, loss_cnaOV22	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.57514663376521	4.4391879630598	0.135958670705405	0.311178497327363	0.573188325589581	0.242978151127876	0.436915377743391	0.237197208379216	0.773999921438189	NA	NA	0.367168467389702	0.554011285037472	83.7398338063975
a8766	loss_cnaOV55	1010	Gefitinib	EGFR	7	23	-0.693147180559945	NA	1.05244686665928	0.886767482108577	0.165679384550704	1.62518175968591	1.1665185884613	0.12956567647909	0.101945141559258	0.142028927948112	0.774008398014656	NA	NA	0.957696148205666	0.808326805981654	83.7398338063975
a8767	gain_cnaOV4_(KRAS)	302	PI-103	PI3Ka, PRKDC (DNAPK)	8	24	2.32630161961136	NA	1.49817957451192	1.22046396562195	0.27771560888997	2.26168462655466	2.36741929901173	0.118521086777124	0.122791482786452	0.117307318144235	0.774212220406397	NA	NA	0.365792093160438	0.771148962333464	83.7398338063975
a8768	SMAD4_mut	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-0.807577347583392	-1.37013923167955	0.56256188409616	2.82102048556574	1.79364020509165	0.299285321690092	0.199417865617995	0.313642547986604	0.774299692003438	NA	NA	0.0754763207270086	0.765023990447413	83.7398338063975
a8769	loss_cnaOV39	1030	KU-55933	ATM	10	23	2.30258509299405	NA	4.27654057680011	4.09640960040487	0.180130976395239	1.22392617937241	0.946457857066875	0.174088883721896	0.147174706637621	0.190321180230333	0.77431723118763	NA	NA	0.531618746447738	0.684747209805218	83.7398338063975
a8770	loss_cnaOV55	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-1.07999793542435	-0.433213192767304	-0.646784742657046	0.389573595854361	2.05144268994917	0.346090126837989	1.66023762785721	0.315282871817916	0.774317377423779	NA	NA	0.0442910460876296	0.268005106201815	83.7398338063975
a8771	loss_cnaOV70	1028	VX-702	p38	3	28	0.693147180559945	NA	3.52326937075874	3.30593706279972	0.217332307959016	0.520218808729798	0.954623248539288	0.233391198771513	0.417770953898553	0.227662911301989	0.774359679988731	NA	NA	0.520189806442807	0.571502436230945	83.7398338063975
a8772	loss_cnaOV57_(ZNRF3)	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	-0.25258716633801	-0.0903792453238738	-0.162207921014136	1.31769019532219	1.26340464427786	0.127810521453283	0.123100195774375	0.128389524091746	0.774509047456739	NA	NA	0.768279366633399	0.829045407700124	83.7398338063975
a8773	loss_cnaOV102	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.52945839073642	3.69717528813631	-0.167716897399893	0.669411775775007	1.08300398822244	0.158154630371132	0.250543691445703	0.154862677537478	0.774546312144942	NA	NA	0.831797077702568	0.724353541989732	83.7398338063975
a8774	gain_cnaOV96	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	4.48259336874476	4.44582033660686	0.0367730321379085	0.860472127129157	1.01098963550074	0.0370605951410665	0.0427358783376244	0.0363733027981982	0.774706907742425	NA	NA	0.0320711894021173	0.934708258716621	83.7398338063975
a8775	loss_cnaOV83	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	3.12077016122373	3.42219938825916	-0.301429227035428	1.8828649438983	1.64512654398536	0.17955347429831	0.160090731951993	0.183225556804407	0.774830286123515	NA	NA	0.631436214292266	0.750679856454459	83.7398338063975
a8776	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	290	KIN001-260	IKK	7	24	2.99573227355399	NA	4.75890390733468	4.87688798773935	-0.117984080404665	0.984248125243147	0.887175502586034	0.129922497347729	0.119872293762834	0.13298843358586	0.775051125036954	NA	NA	0.666950192784669	0.781941743670404	83.7398338063975
a8777	gain_cnaOV48_(SOX17)	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.91572999787411	4.78258870201082	0.133141295863289	0.530991334791764	0.677265217609976	0.199161233996932	0.250740995454289	0.196586643461679	0.775063877442898	NA	NA	0.763223014008869	0.717247423753248	83.7398338063975
a8778	PIK3CA_mut	1149	TW 37	BCL2, BCL2L1	7	26	1.6094379124341	NA	-1.18838712430438	-0.619778460447901	-0.568608663856474	0.647285500632064	0.950375714307028	0.631986002992405	0.878451105889498	0.598298815191294	0.775118128554337	NA	NA	0.0428550106548566	0.0859256364069826	83.7398338063975
a8779	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.40177537032995	2.52209989135434	-0.120324521024386	0.497617763368142	0.642179703141966	0.189915337379078	0.241801096910139	0.187368925607084	0.775162508237265	NA	NA	0.858792587852899	0.726928848357735	83.7398338063975
a8780	gain_cnaOV96	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.80002293991335	5.69934202302381	0.100680916889536	0.570539382861459	0.465021900593084	0.209563407327705	0.176466200079975	0.216507903737712	0.775232214041459	NA	NA	0.384029624900019	0.724796303302941	83.7398338063975
a8781	loss_cnaOV85	1009	ATRA	Retinoic acid and retinoid X receptor agonist	7	24	2.30258509299405	NA	4.55211575436134	4.4998666011054	0.0522491532559384	1.08098541526557	0.885662374207867	0.0562152593264215	0.048334743945738	0.0589944371326261	0.775253164569401	NA	NA	0.53050557309784	0.909621686142029	83.7398338063975
a8782	loss_cnaOV35	265	Tubastatin A	HDAC6	5	26	2.99573227355399	NA	4.83176788470837	4.74176370662076	0.0900041780876162	1.50691798204626	1.18929987732783	0.0727034125148605	0.0597273236897726	0.0756782875399273	0.775263296962158	NA	NA	0.427198434228365	0.904480459660833	83.7398338063975
a8783	gain_cnaOV18_(CCNE1)	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	0.636191569490575	0.775703371206854	-0.139511801716279	1.57224397632175	0.981433127393126	0.132175750331285	0.0887341938130143	0.14215110313919	0.775301836125965	NA	NA	0.77301509806935	0.872806981660614	83.7398338063975
a8784	gain_cnaOV18_(CCNE1)	255	CP724714	ERBB2	4	28	2.32630161961136	NA	4.52700737389067	4.39907843417825	0.127928939712421	0.643968579862828	0.985944375509755	0.133640706802685	0.198657114202172	0.129752694868084	0.775357076602427	NA	NA	0.787475665418669	0.74420686018512	83.7398338063975
a8785	loss_cnaOV81_(RB1)	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	9.00885668808185	8.7218024053245	0.287054282757344	1.46347123738603	1.22457708363948	0.231024395208441	0.196146173169802	0.234410954273463	0.775389308290803	NA	NA	0.532001507266706	0.770520213095416	83.7398338063975
a8786	loss_cnaOV82	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.86474482954761	-2.34160556903643	0.476860739488819	1.46602973164282	1.63284401443447	0.293886918140091	0.32527358019844	0.292043045920695	0.775472849503463	NA	NA	0.126055164982974	0.638284897123998	83.7398338063975
a8787	ARID1A_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	1.6094379124341	NA	1.14862531943877	1.17509209332029	-0.026466773881519	0.857888729189876	1.67220749156404	0.0175875994640036	0.0308510567641006	0.0158274460645815	0.775577364286962	NA	NA	0.813945830511196	0.95303303802893	83.7398338063975
a8788	loss_cnaOV38	291	KIN001-266	MAP3K8 (COT)	8	24	2.99573227355399	NA	3.20966234970701	3.33336747309581	-0.123705123388795	0.801846945809835	1.19381288158156	0.110971129369131	0.154275231744953	0.103621870141752	0.775593331300009	NA	NA	0.951166411126312	0.744503469595916	83.7398338063975
a8789	loss_cnaOV20	286	KIN001-236	TIE2	5	27	2.32630161961136	NA	4.88802041434908	4.77785778815521	0.110162626193866	0.771065471473942	0.651211915526932	0.164806738254247	0.142870651415999	0.169165556660197	0.7757343402398	NA	NA	0.763225023101922	0.775810114561177	83.7455288316032
a8790	gain_cnaOV94	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	2.4750696452502	2.44253869396783	0.032530951282375	1.84535165776266	1.55394392606752	0.0203186382453568	0.0176285918976637	0.0209344434742246	0.77590973569505	NA	NA	0.230855376175148	0.97542732930775	83.7470361113208
a8791	loss_cnaOV16, loss_cnaOV17	1026	17-AAG	HSP90	6	27	0	NA	-0.445676231753063	-0.54975569752049	0.104079465767427	1.56714151436281	2.43284546624225	0.044954558701936	0.0664135719802848	0.0427809604891129	0.775924829254119	NA	NA	0.0624525096791441	0.897887400581675	83.7470361113208
a8792	PTEN_mut	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.21194077709194	4.34193478687521	-0.129994009783268	0.176497983574061	0.610653219705679	0.219941012583549	0.736518384804784	0.212876974342201	0.776155265933074	NA	NA	0.256395015939154	0.419676932053272	83.7623793814856
a8793	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.28462856236042	4.33414680988216	-0.0495182475217391	0.607298847483897	0.591045931637255	0.083620101811245	0.0815385172010425	0.0837807095373598	0.776327390916082	NA	NA	0.256396094391312	0.903319691465322	83.7714269015282
a8794	gain_cnaOV4_(KRAS)	1003	Camptothecin	TOP1	5	26	-2.30258509299405	NA	-3.52709265531472	-3.72272083875855	0.195628183443829	1.38954489577363	1.79197136996784	0.112300896959985	0.14078579543478	0.109169257233914	0.776637642914745	NA	NA	0.24753761451602	0.792140016578184	83.7839666844896
a8795	loss_cnaOV33_(ZFHX3)	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	2.48736620226112	2.28919897852021	0.198167223740912	1.09250726677751	1.48939767035427	0.13623579335676	0.181387556647958	0.133051922723752	0.776684736542879	NA	NA	0.821808450002025	0.760747420991354	83.7839666844896
a8796	loss_cnaOV35	151	QS11	ARFGAP	3	16	2.32630161961136	NA	4.18422046906354	3.6885092901814	0.495711178882144	2.09564229369043	1.36025966697046	0.338127596512482	0.236543793935938	0.364423933840647	0.776716232687672	NA	NA	0.0668157615845307	0.726543764333955	83.7839666844896
a8797	loss_cnaOV38	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	2.52593003591616	2.75778348904434	-0.231853453128188	2.29681799154287	1.03516166588678	0.172173249951264	0.100945505469696	0.223978013066749	0.776880701339233	NA	NA	0.941653206551145	0.855506988452373	83.7839666844896
a8798	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.34782120442054	6.76323312142538	-0.415411917004834	0.655131128883444	1.60785393667424	0.272055064806152	0.6340897244691	0.258364213023037	0.776948935010775	NA	NA	0.341199098864585	0.473904979816739	83.7839666844896
a8799	loss_cnaOV70	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.55216335641117	3.24764202647289	0.304521329938281	0.300974577937005	1.07956874392377	0.29117012387102	1.01178422452018	0.28207683081994	0.776973414523056	NA	NA	0.0934618264830373	0.278704436799383	83.7839666844896
a8800	gain_cnaOV50	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.94338233103337	2.84726262390681	0.0961197071265545	1.34736635636007	1.10218880004657	0.0851291248575413	0.0713389544520197	0.0872080238181455	0.777267152266103	NA	NA	0.393083765059664	0.898857140375424	83.7957599125747
a8801	gain_cnaOV50	1218	JQ1	BRD2, BRD3, BRD4	4	27	0	NA	2.1345896087183	2.31759970310554	-0.183010094387235	1.01311729920181	0.892876998013157	0.201985429402678	0.180640577879207	0.20496674770934	0.777272213465257	NA	NA	0.596273208289946	0.750676593601749	83.7957599125747
a8802	loss_cnaOV82	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.69227478683912	3.94424139608296	-0.251966609243841	1.15137466856961	1.23487832166053	0.204967288773373	0.218839806122247	0.204041649144041	0.777347724108994	NA	NA	0.700214356519365	0.748407715849382	83.7957599125747
a8803	gain_cnaOV51_(MYC)	1175	AG-014699	PARP1, PARP2	8	25	1.6094379124341	NA	3.88976806907835	3.90480268873139	-0.015034619653036	1.15352231237825	1.06209117619358	0.0138771081620165	0.013033661760767	0.0141556770172204	0.777696690086019	NA	NA	0.318687945381822	0.97449906086184	83.8163759050878
a8804	MLL2_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.5102036643612	1.3216506932577	0.188552971103503	0.371059203055689	1.40816366391811	0.138415064915709	0.508147943915043	0.133899898097688	0.777795102146313	NA	NA	0.582771551195417	0.5920472473687	83.8163759050878
a8805	loss_cnaOV1	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.36226360032828	5.17306167167845	0.189201928649838	0.473175021930907	0.792820834585749	0.24393627583063	0.399856120633233	0.2386439916765	0.778001935607446	NA	NA	0.335962932361637	0.581398962960749	83.8163759050878
a8806	loss_cnaOV85	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	7	26	-1.38629436111989	0.693147180559945	-2.26224120442132	-2.30795050495333	0.0457093005320037	1.65051178880117	1.62334478627622	0.0280659622259643	0.0276940163906397	0.0281574813424917	0.778045893568684	NA	NA	0.12606691447675	0.949333735448636	83.8163759050878
a8807	gain_cnaOV94	1377	Afatinib (rescreen)	ERBB2, EGFR	7	26	2.30258509299405	NA	2.7566432338874	2.62777402023	0.128869213657401	1.15570670026839	1.82509192116108	0.0750971183278312	0.111506849988386	0.0706097113045228	0.778143617956917	NA	NA	0.6416303427532	0.822550617642037	83.8163759050878
a8808	loss_cnaOV102	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.85679002817819	2.8644891184799	-0.00769909030170535	0.859323396541032	0.806283350475756	0.00950590148628554	0.0089594794377715	0.00954886430082231	0.778173939955617	NA	NA	0.0200411622396968	0.98930087060906	83.8163759050878
a8809	loss_cnaOV81_(RB1)	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.496018589152357	0.36543128325981	0.130587305892547	0.297219133378989	0.964054969773923	0.142279701489949	0.439363726042607	0.135456286194106	0.778214422068322	NA	NA	0.910113871495919	0.590673244605052	83.8163759050878
a8810	loss_cnaOV21, loss_cnaOV22	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.34803255751514	1.51319134211747	-0.165158784602328	0.820908765026291	1.76475242155812	0.096132219793229	0.201190182927378	0.0935875098312696	0.778245665387086	NA	NA	0.318471985489509	0.787685527006919	83.8163759050878
a8811	loss_cnaOV16, loss_cnaOV17	1001	AICAR	AAPK1 (AMPK) agonist	6	25	7.60090245954208	NA	8.93999694656926	8.70388222935664	0.236114717212621	0.999107765269714	1.28670829093776	0.190126397823574	0.236325575098378	0.183502911169197	0.778570243015597	NA	NA	0.53201891381154	0.63558326712696	83.8209585883212
a8812	KRAS_mut	192	LFM-A13	BTK	3	16	2.77258872223978	NA	4.82155634100076	4.70699693619815	0.114559404802609	0.357574331823921	0.732082482769005	0.164002280731238	0.320379273921208	0.15648428626417	0.77873330373132	NA	NA	0.957297655350102	0.692663172329821	83.8209585883212
a8813	gain_cnaOV48_(SOX17)	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.34701251751257	2.44923543897458	-0.102222921462011	0.765444891643501	1.50772410185681	0.0695419196443556	0.133547068610683	0.067799487542927	0.778807259905947	NA	NA	0.242399749573579	0.854878391304927	83.8209585883212
a8814	ARID1A_mut	1262	UNC1215	LMBL3	9	24	0	NA	2.59600592378663	2.84956524732186	-0.253559323535227	0.451200906867531	0.496223649135915	0.522797172759917	0.561965456354168	0.510977910820564	0.778812467582731	NA	NA	0.111343931682926	0.18136267584828	83.8209585883212
a8815	gain_cnaOV51_(MYC)	261	TL-1-85	MAP3K7 (TAK1)	8	24	2.32630161961136	NA	3.61578883819142	3.53553529001377	0.0802535481776525	0.897754666469881	0.98726885135042	0.0829816911534353	0.089393629657446	0.0812884434345103	0.778924386012412	NA	NA	0.729758664474669	0.834251233666878	83.8209585883212
a8816	loss_cnaOV55	304	SB52334	ALK5	7	25	2.99573227355399	NA	4.19985191455845	4.41334127367489	-0.213489359116439	1.09271687462771	1.06086798588907	0.200024922189788	0.195374816728418	0.201240269247566	0.779026564639278	NA	NA	0.354171499556106	0.656094973478174	83.8209585883212
a8817	BRCA1_mut	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-3.86512915304744	-4.21637387814034	0.351244725092903	0.683126214837464	1.38151237657957	0.260901718617164	0.514172516679769	0.254246527969973	0.77903823872631	NA	NA	0.219956305728193	0.496836749283942	83.8209585883212
a8818	loss_cnaOV35	1023	GW 441756	NTRK1	5	26	0.693147180559945	NA	2.13196872677933	2.3304878505372	-0.198519123757866	1.48357080926523	1.22652026361736	0.156921625881194	0.133811694405195	0.161855559705452	0.779044476643094	NA	NA	0.845303916155876	0.789526792904823	83.8209585883212
a8819	gain_cnaOV50	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	1.97865598847177	1.64145855527947	0.3371974331923	0.839387906921287	1.54753427019766	0.2260153539286	0.401718240651184	0.217893354406446	0.779142952760099	NA	NA	0.328796761197981	0.532590654879871	83.8209585883212
a8820	gain_cnaOV26	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.68709946173616	4.06844063404175	-0.38134117230559	2.363988495478	1.42461217102997	0.25328465993732	0.161312617652347	0.267680692373902	0.779195189385754	NA	NA	0.332100808514914	0.807958787033485	83.8209585883212
a8821	PIK3R1_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-1.89478825262234	-2.16443077758613	0.269642524963781	1.27767940755552	1.3032467554619	0.207421156391189	0.211040831815288	0.206900591797915	0.779441082983497	NA	NA	0.609258116307158	0.680957177274082	83.8209585883212
a8822	PIK3CA_mut	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	6	26	2.32630161961136	NA	4.90111176049339	5.19813005788681	-0.297018297393417	0.457711327499431	0.600748511314865	0.512660426000921	0.648920574057207	0.494413705234707	0.779477552987491	NA	NA	0.0122694291499579	0.210092088402682	83.8209585883212
a8823	gain_cnaOV94	1495	AZD-2281	PARP1, PARP2	7	26	2.30258509299405	NA	3.57723939321923	3.55692783937752	0.0203115538417067	0.666331057709576	0.976428507412645	0.0219688239665022	0.0304826761512887	0.020801885327507	0.779497571690222	NA	NA	0.144760687750178	0.949729974725665	83.8209585883212
a8824	loss_cnaOV16, loss_cnaOV17	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	6	25	3.68887945411394	NA	3.57786872668374	3.46842897617271	0.109439750511034	0.559322754412985	1.20720909940497	0.0974957433895668	0.195664756435472	0.0906551736273161	0.779561487475966	NA	NA	0.728142328648531	0.745755509421157	83.8209585883212
a8825	loss_cnaOV57_(ZNRF3)	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-4.2834719455666	-4.02663233439084	-0.256839611175754	1.54443880711719	1.53380365871956	0.167332331566624	0.166299635823813	0.16745273080791	0.780006966229569	NA	NA	0.864777333963616	0.771821187973648	83.8209585883212
a8826	loss_cnaOV36	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.09951790200027	4.30359904635324	-0.204081144352974	0.709248577920758	0.83150287522899	0.247775235659072	0.287742761432474	0.245436486670923	0.780045805123523	NA	NA	0.3193195163699	0.677513359256015	83.8209585883212
a8827	ARID1A_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	1.38629436111989	NA	1.56225719754208	1.08623518811043	0.476022009431649	0.663475608797538	1.37268621398755	0.387175524614899	0.717467233338655	0.34678137259705	0.780144502239776	NA	NA	0.269202555701176	0.192868214922406	83.8209585883212
a8828	loss_cnaOV38	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	8	24	2.30258509299405	NA	0.994886036048884	0.827374855373571	0.167511180675312	1.82058076210215	1.02155438113102	0.133541424507997	0.0920097499447891	0.163976763028367	0.780156028103762	NA	NA	0.845652867434721	0.810327002051853	83.8209585883212
a8829	loss_cnaOV38	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	2.41299210658087	2.51328387301783	-0.100291766436965	1.53593309480533	0.485688209083283	0.128349976654739	0.0652969629837138	0.206494134634772	0.780226700304438	NA	NA	0.751440183746014	0.905213206389736	83.8209585883212
a8830	loss_cnaOV102	303	PIK-93	PI4K, PI3K	3	29	2.99573227355399	NA	2.61264327080535	2.93560013724538	-0.322956866440033	0.607278412098598	1.28808048030814	0.257491338328485	0.531810220824378	0.250727242107399	0.780325097001056	NA	NA	0.23386842456752	0.486927401897905	83.8209585883212
a8831	gain_cnaOV18_(CCNE1)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.60818959366536	4.50132285450224	0.106866739163112	0.635388862932951	0.947291225233632	0.115015814444867	0.168191080136054	0.112812972733655	0.780326265104365	NA	NA	0.530533281854498	0.810143744602894	83.8209585883212
a8832	gain_cnaOV19	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.60818959366536	4.50132285450224	0.106866739163112	0.635388862932951	0.947291225233632	0.115015814444867	0.168191080136054	0.112812972733655	0.780326265104365	NA	NA	0.530533281854498	0.810143744602894	83.8209585883212
a8833	loss_cnaOV70	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.79408358566313	2.4954124459334	0.298671139729731	1.06534332824701	1.04190326423896	0.286194486890574	0.280352006541576	0.286659184188169	0.780359252287956	NA	NA	0.198005541783695	0.682203996110963	83.8209585883212
a8834	loss_cnaOV85	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.32261746323322	4.33131975504788	-0.0087022918146582	0.725708154386499	0.552307279920485	0.0146908187459216	0.0119914483006119	0.015756250426232	0.780455001237088	NA	NA	0.256421680902189	0.977296831261163	83.8209585883212
a8835	TP53_mut	221	TAK-715	p38a	22	10	2.99573227355399	2.32630161961136	4.30485945222614	4.21871799726241	0.0861414549637223	1.03183414329342	0.479064561577723	0.0954697631071641	0.0834838191036932	0.179811787121195	0.78053697804185	NA	NA	0.523604904499006	0.7493152301236	83.8209585883212
a8836	gain_cnaOV4_(KRAS)	1050	ZM-447439	AURKB	6	16	1.38629436111989	0.693147180559945	2.35415809185193	2.48381415758188	-0.129656065729955	1.6814725332343	1.57183408363839	0.0810376644035586	0.0771086432679115	0.0824871193973827	0.780650355904932	NA	NA	0.230897586770983	0.873621694726569	83.8209585883212
a8837	loss_cnaOV20	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	2.69547157103245	2.21070772596008	0.484763845072366	1.08933989321219	1.87850793382456	0.269872661276975	0.445006969902589	0.258057917320269	0.780745607295066	NA	NA	0.112196388281951	0.442007620356014	83.8209585883212
a8838	SMAD4_mut	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.51398780794822	4.42261700897346	0.0913707989747561	1.44133853540479	0.666146524438675	0.122906961422135	0.0633930174836373	0.137163215032532	0.780838662286606	NA	NA	0.52640605987852	0.923051619938187	83.8209585883212
a8839	loss_cnaOV85	261	TL-1-85	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	3.62290340074593	3.53675335442561	0.0861500463203155	1.28763728285893	0.868663632707657	0.0890817215497793	0.0669055233699333	0.0991753805230485	0.780850118368495	NA	NA	0.729765040160173	0.871948899646465	83.8209585883212
a8840	loss_cnaOV55	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	3.51732235006434	3.68928616295692	-0.171963812892576	3.08256332589176	1.59672526352792	0.0841926696109831	0.0557859789767103	0.107697809272854	0.78099330831503	NA	NA	0.748618330097598	0.883455670900907	83.8268456759685
a8841	loss_cnaOV85	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	-1.38629436111989	0.693147180559945	-2.29451689296056	-2.07755326095382	-0.21696363200674	1.93538213349628	1.09476353444879	0.16682044241983	0.112103769199726	0.198183100897657	0.781237447816506	NA	NA	0.609265999299839	0.784115966715974	83.8331112030973
a8842	loss_cnaOV38	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	1.94125562929853	1.83926212250734	0.10199350679119	2.42107838566602	1.48370388811249	0.0604443508731484	0.0421273046734225	0.0687424947850895	0.781309179359638	NA	NA	0.350144695344877	0.940214209674811	83.8331112030973
a8843	ARID1A_mut	196	Phenformin	AAPK1 (AMPK) agonist	8	23	8.29404964010203	NA	8.67855203096941	8.78497175872315	-0.106419727753744	1.4259978565929	1.80705171449306	0.0617711170286998	0.0746282522527838	0.0588913570653393	0.781316745419037	NA	NA	0.922195776236979	0.867926494327852	83.8331112030973
a8844	PIK3CA_mut	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.36411030251037	2.53790535778851	-0.173795055278136	0.634651288544498	0.817553942277891	0.223273843816698	0.273843382051134	0.212579312863324	0.781535149404638	NA	NA	0.751447508951469	0.638928173501376	83.8377502017292
a8845	loss_cnaOV21, loss_cnaOV22	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.35361044447497	4.45087873028251	-0.0972682858075382	0.902929557490552	1.02486139017391	0.0956013915569562	0.107725220644974	0.0949087230137851	0.781547559764475	NA	NA	0.377203758212754	0.873610006127173	83.8377502017292
a8846	SMARCA4_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.36215699739546	3.50326663472263	-0.141109637327172	0.662651365231455	1.14933936083176	0.125702372766723	0.212947025737861	0.122774562619218	0.78187396267194	NA	NA	0.728150272404074	0.766767361043457	83.8377502017292
a8847	loss_cnaOV55	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	7	25	1.63315443905142	NA	2.8091381551699	2.8790634973705	-0.0699253422005945	0.779907164816902	0.816582391520969	0.0863936788790397	0.0896585457283379	0.0856317046836527	0.781957165135672	NA	NA	0.0200466274327966	0.839781476992465	83.8377502017292
a8848	KRAS_mut	134	Etoposide	TOP2	3	16	2.77258872223978	NA	2.28711604134975	2.28259730941468	0.00451873193506724	1.86247714871751	1.85224589474892	0.0024380079487474	0.00242619456468436	0.00243959613994975	0.781964412819219	NA	NA	0.413234256251464	0.997178975689543	83.8377502017292
a8849	loss_cnaOV52, loss_cnaOV53	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.87649715586797	1.51469771409566	0.361799441772316	0.229435452922766	1.3619630035649	0.286253854583747	1.57691166366563	0.265645572475402	0.782091053942726	NA	NA	0.166825158928127	0.289424228363313	83.8377502017292
a8850	loss_cnaOV55	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.87649715586797	1.51469771409566	0.361799441772316	0.229435452922766	1.3619630035649	0.286253854583747	1.57691166366563	0.265645572475402	0.782091053942726	NA	NA	0.166825158928127	0.289424228363313	83.8377502017292
a8851	PIK3R1_mut	1007	Docetaxel	Microtubules	4	27	-4.38202663467388	NA	-5.17297753863452	-4.57088571834253	-0.602091820291983	1.13817530123191	1.4465875420979	0.424667044079943	0.52899743970925	0.416215267151275	0.782183119175019	NA	NA	0.137389276097225	0.389357836703558	83.8377502017292
a8852	gain_cnaOV96	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	1.6044314327398	1.40782119048471	0.196610242255088	0.310492438508905	1.90248954404289	0.108975745520329	0.633220709654896	0.10334366507859	0.782271154591833	NA	NA	0.616462023350826	0.624855641405334	83.8377502017292
a8853	gain_cnaOV26	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	3.11984237948198	2.71065770022011	0.409184679261879	2.5464034383366	1.61076009072469	0.242216273994722	0.160691221627148	0.254032044634148	0.782292652551087	NA	NA	0.323688824039123	0.808854983868328	83.8377502017292
a8854	loss_cnaOV42	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	2.81270209820408	3.04045025266546	-0.227748154461371	1.63418037983197	1.00928271983494	0.209318771961937	0.139365370721676	0.225653476459616	0.782331931122992	NA	NA	0.43680504891212	0.802008153183224	83.8377502017292
a8855	gain_cnaOV18_(CCNE1)	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.56053073262964	3.69872627134442	-0.138195538714786	0.918114381593607	1.07528099093588	0.130297812485326	0.150521047796805	0.128520395952044	0.782601660212077	NA	NA	0.83181422972514	0.795907855135542	83.8497312281073
a8856	loss_cnaOV56	308	XL-880	MET	3	29	1.63315443905142	NA	0.342466540047012	0.243853420776851	0.0986131192701612	0.576687682631575	1.0012663406624	0.100758439012363	0.170999177267259	0.09848839940522	0.782674407734538	NA	NA	0.37065486155116	0.810756964024653	83.8497312281073
a8857	gain_cnaOV51_(MYC)	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-4.18263482508719	-4.18371463852145	0.001079813434262	1.04807357575697	1.42980188311585	0.000799614123360556	0.00103028399841309	0.00075521892019673	0.782757722418308	NA	NA	0.21997755095457	0.998200963812431	83.8497312281073
a8858	PIK3CA_mut	1004	Vinblastine	Microtubules	7	24	-2.30258509299405	NA	-3.99236255946803	-3.11767881037141	-0.874683749096619	1.44985341109497	1.87939853240915	0.486215855422993	0.603291161991358	0.465406210557899	0.782797219182015	NA	NA	0.141438866182593	0.214486235507997	83.8497312281073
a8859	loss_cnaOV21, loss_cnaOV22	1026	17-AAG	HSP90	3	30	0	NA	-0.55150729742519	-0.528764644376535	-0.0227426530486554	3.36311168818177	2.22522802459098	0.00982159838305274	0.00676238411247978	0.0102203696867586	0.782916428397624	NA	NA	0.062473905682444	0.99181719991814	83.8518481859368
a8860	gain_cnaOV48_(SOX17)	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	2.36745499328133	2.60997098469359	-0.242515991412256	2.13689279468178	2.36715408353704	0.10308842339911	0.113490013170442	0.102450445916848	0.782993730518058	NA	NA	0.388320937892013	0.866882231603504	83.8518481859368
a8861	loss_cnaOV33_(ZFHX3)	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	2.26991846909893	2.28612070019478	-0.0162022310958561	1.65948223510871	1.82011005546376	0.00897535956242437	0.00976342545468389	0.00890178648660217	0.783258250719414	NA	NA	0.11220694723282	0.986424431761012	83.8573075986925
a8862	PIK3CA_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	1.6094379124341	NA	1.59485794598232	1.26553436593429	0.32932358004803	0.63684615785102	1.48747653756432	0.242864947812834	0.517116380444694	0.221397495510944	0.783358108191252	NA	NA	0.582799069075117	0.403667702596965	83.8573075986925
a8863	loss_cnaOV52, loss_cnaOV53	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.59674618736587	2.45482111319726	0.141925074168612	0.283781722579478	0.877724291087528	0.182003380903147	0.500120560544077	0.161696646213087	0.78343954362977	NA	NA	0.751458083827083	0.601525160994791	83.8573075986925
a8864	gain_cnaOV51_(MYC)	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	3.86273210625376	3.57414957756045	0.288582528693317	1.82780120971795	2.10016926728798	0.141470889468757	0.157885073693462	0.137409176102254	0.783613914137394	NA	NA	0.748626349954388	0.715486427820638	83.8573075986925
a8865	gain_cnaOV96	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.11218449259787	1.90733674579417	0.204847746803708	1.07006780582033	1.38897945534677	0.151647510979614	0.191434361158701	0.14748076079539	0.783827371424506	NA	NA	0.839844266394125	0.720024107162999	83.8573075986925
a8866	loss_cnaOV1	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.08440230444052	3.24473016921291	-0.160327864772388	1.16113608699712	1.24566499764475	0.129274877282175	0.138078444523261	0.128708653671355	0.783965881529654	NA	NA	0.602742605026195	0.838311196150658	83.8573075986925
a8867	loss_cnaOV44	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.03062496257475	4.84241963435891	0.188205328215843	0.655440180626378	0.620551350290103	0.30212526449558	0.28714340954194	0.303287275304225	0.784190130125584	NA	NA	0.0507356844110021	0.674294735057739	83.8573075986925
a8868	gain_cnaOV4_(KRAS)	291	KIN001-266	MAP3K8 (COT)	8	24	2.99573227355399	NA	3.39830765919958	3.27048570326495	0.127821955934636	1.05632723980931	1.13181381078806	0.114673738174649	0.121006020783589	0.112935497620086	0.784361614736601	NA	NA	0.951171872268741	0.775659457265093	83.8573075986925
a8869	PTEN_mut	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.54029281069835	2.73421618250421	-0.193923371805858	0.19096513825677	0.588995317355118	0.339527966010601	1.01549096120942	0.329244335382274	0.784378131909001	NA	NA	0.137500104405308	0.250011685162263	83.8573075986925
a8870	loss_cnaOV58	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-2.29209390055261	-2.29935471632045	0.00726081576783821	1.91898310715946	1.58122850827261	0.00445790634534774	0.00378367883528995	0.0045918826594963	0.784435689410653	NA	NA	0.126095447146211	0.993932870346424	83.8573075986925
a8871	loss_cnaOV70	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.6053549898167	4.50162656205746	0.103728427759243	0.464402620627779	0.954649969859493	0.111634199932795	0.223358833804649	0.10865597971423	0.784564747877563	NA	NA	0.530555895109297	0.763720625681311	83.8573075986925
a8872	gain_cnaOV26	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.75082278287886	4.50602171579134	0.244801067087521	0.860321239673548	1.00209975904866	0.246386945172168	0.284546115797875	0.244288120895191	0.784601573366884	NA	NA	0.327823454744388	0.679949093568076	83.8573075986925
a8873	MLL2_mut	1030	KU-55933	ATM	3	30	2.30258509299405	NA	3.77264057830627	4.18883016141314	-0.416189583106877	0.672856341079659	1.05106590430599	0.403729999632247	0.618541518742415	0.395969064738795	0.784685158534912	NA	NA	0.531671027917615	0.405918756570207	83.8573075986925
a8874	gain_cnaOV94	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	1.51277796905197	1.57712839560743	-0.0643504265554558	0.720018743175189	1.15336125311692	0.0593498549740249	0.0893732658564953	0.0557938168822223	0.784686063401287	NA	NA	0.457361774555578	0.881533039392118	83.8573075986925
a8875	loss_cnaOV82	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	2.32326468225915	2.14999895421174	0.173265728047417	1.35835627239454	1.30853757901063	0.132058862113864	0.127555437088666	0.132411732629353	0.785011730658077	NA	NA	0.688071310867876	0.849592829318297	83.8573075986925
a8876	SMARCA4_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	3	30	2.30258509299405	NA	2.98682117523618	2.62193878791611	0.364882387320065	1.71945272863651	1.71306752841502	0.212948120682566	0.212208443560649	0.212999418451218	0.785094702623788	NA	NA	0.641658583165863	0.754188271092902	83.8573075986925
a8877	gain_cnaOV94	1072	BMS-708163	g-secretase	7	26	1.6094379124341	NA	3.75544174545428	3.86451232041411	-0.109070574959831	0.903800074310992	0.862289632053445	0.125299574750116	0.120679980075218	0.126489489036406	0.785116726345862	NA	NA	0.924114103327257	0.781126353064391	83.8573075986925
a8878	loss_cnaOV16, loss_cnaOV17	273	CUDC-101	HDAC, EGFR	6	25	1.63315443905142	NA	-0.129754425881018	0.177552864844099	-0.307307290725118	1.32763429941531	1.68868062970887	0.188284969134785	0.231469833869504	0.181980704532684	0.785118386512826	NA	NA	0.464188393764014	0.641439982961992	83.8573075986925
a8879	loss_cnaOV44	1241	CHIR-99021	GSK3B	3	29	2.30258509299405	NA	3.5376208421093	3.69633089661498	-0.158710054505681	0.683449921788064	1.08250938416311	0.149643580272473	0.232218995783127	0.1466130980734	0.785140659397481	NA	NA	0.831819492751215	0.742682995861109	83.8573075986925
a8880	BRCA1_mut	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	0.122574667358233	0.39183970568883	-0.269265038330597	1.29951130976656	1.72635212742863	0.159591775050251	0.207204844087864	0.155973415882229	0.7854087321508	NA	NA	0.838047333268241	0.728063423982937	83.8573075986925
a8881	gain_cnaOV96	330	XMD13-2	RIPK	5	27	2.32630161961136	NA	4.22922968634424	4.05713192181496	0.172097764529279	1.09067840322842	1.13327160160731	0.152611495093279	0.157789650936397	0.151859240349086	0.785428840263627	NA	NA	0.82052398298889	0.758816527688215	83.8573075986925
a8882	loss_cnaOV54	276	CAY10603	HDAC6	10	21	2.99573227355399	NA	1.24331241767607	1.52360827129932	-0.280295853623254	1.37500871350504	1.96191176502104	0.155688608356388	0.203850238089583	0.14286873580181	0.785538721666017	NA	NA	0.616476901162401	0.650031588463146	83.8573075986925
a8883	loss_cnaOV52, loss_cnaOV53	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	-0.702479681648453	-0.502836233780511	-0.199643447867942	0.397583774287759	1.70702957451198	0.132639303665206	0.502141839730728	0.116953713543608	0.785614603649304	NA	NA	0.91002358495775	0.688860513589461	83.8573075986925
a8884	loss_cnaOV81_(RB1)	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.1631420252207	3.32234107325259	-0.159199048031897	1.13304692539576	1.1127508081088	0.14280540866941	0.140505255752131	0.143068013855202	0.785755008867541	NA	NA	0.951172717945321	0.805617669617621	83.8573075986925
a8885	loss_cnaOV85	1502	Bicalutamide	ANDR (androgen receptor)	6	26	2.30258509299405	NA	4.59998795476862	4.49682409406452	0.103163860704095	0.317047026979673	0.644781869687787	0.171179190460181	0.32538977478161	0.159998079279196	0.785880595035982	NA	NA	0.616826475275328	0.576439383544962	83.8573075986925
a8886	loss_cnaOV42	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-2.00643050389905	-2.13973382827335	0.133303324374296	0.548074571672068	1.35926581007078	0.102303008695612	0.243221144100179	0.0980700929771447	0.785883203686974	NA	NA	0.609286055880191	0.728304515944703	83.8573075986925
a8887	loss_cnaOV57_(ZNRF3)	152	CP466722	ATM	4	28	2.77258872223978	NA	2.78467079959616	2.62723752578709	0.157433273809063	0.88784406792283	0.810812127249249	0.192263430632558	0.177320860156658	0.194167389112899	0.786340030347709	NA	NA	0.557899722716303	0.755348705645601	83.8573075986925
a8888	gain_cnaOV96	150	Bicalutamide	ANDR (androgen receptor)	4	15	0.0237165266173161	NA	2.9097057536062	2.99335512614033	-0.0836493725341336	0.834715961504228	0.548859894519922	0.137325501403689	0.100212978296702	0.152405692908753	0.786568837734356	NA	NA	0.850895887541735	0.859376358717603	83.8573075986925
a8889	ARID1A_mut	298	OSI-930	KIT, VEGFR, PDGFR	8	24	2.32630161961136	NA	3.97293594435038	4.61110951572108	-0.638173571370694	0.812173101840557	0.988652706453723	0.671472022143553	0.785760535438144	0.645498229261729	0.786598444440649	NA	NA	0.0320952358891669	0.0896685490991224	83.8573075986925
a8890	loss_cnaOV57_(ZNRF3)	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	3.40075713482074	3.56488917811142	-0.164132043290678	1.0625092182593	0.891303134628263	0.180389746703137	0.154475876980695	0.184148396784369	0.786811956087998	NA	NA	0.664864133160575	0.784438172555276	83.8573075986925
a8891	gain_cnaOV72_(ASXL1)	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.16254017198564	2.34201242028452	-0.179472248298878	0.719293131870119	1.53681727826168	0.12338187651605	0.249511972722806	0.116781774149418	0.786852334100827	NA	NA	0.82183097491374	0.68836492372831	83.8573075986925
a8892	KRAS_mut	254	AC220	FLT3	7	25	0.0237165266173161	NA	2.46401061676475	2.52392594571649	-0.0599153289517385	0.328400320415115	0.689654198015696	0.094490547133586	0.182446012464307	0.086877349727051	0.786938998742221	NA	NA	0.858813476954013	0.749867087042624	83.8573075986925
a8893	gain_cnaOV4_(KRAS)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	0.693147180559945	2.67359321728732	2.85908553314851	-0.185492315861188	2.17657460517421	1.38681326474126	0.118075183987964	0.0852221262805467	0.133754356536095	0.787242685324039	NA	NA	0.968963768488453	0.83629339350991	83.8573075986925
a8894	loss_cnaOV41	152	CP466722	ATM	5	27	2.77258872223978	NA	2.7711974465874	2.62390172916616	0.147295717421238	0.960267815127924	0.794737562362437	0.17990445070658	0.15339024707562	0.185338814216088	0.787291847673173	NA	NA	0.557904317976154	0.759521772366127	83.8573075986925
a8895	loss_cnaOV34	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	5	18	2.30258509299405	NA	3.94477159749977	3.82826311358894	0.116508483910837	1.2857866130819	0.770766473409883	0.130601522777495	0.0906126123304222	0.151159252419739	0.787298848761305	NA	NA	0.940303480376767	0.854665069200812	83.8573075986925
a8896	loss_cnaOV16, loss_cnaOV17	256	JW-7-24-1	LCK	6	26	2.32630161961136	NA	2.09333715923272	1.90380737092444	0.189529788308283	0.763281586594497	1.43986056062659	0.140305271180397	0.24830913209095	0.131630654725208	0.787396744700086	NA	NA	0.8398512599457	0.658819592732186	83.8573075986925
a8897	loss_cnaOV38	330	XMD13-2	RIPK	8	24	2.32630161961136	NA	4.00835083711973	4.10924598432364	-0.100895147203905	1.33869851971424	1.0564359579604	0.0893961995417497	0.0753680875253693	0.0955052186965483	0.787468465293288	NA	NA	0.820528425517829	0.850041009091249	83.8573075986925
a8898	gain_cnaOV4_(KRAS)	172	Embelin	XIAP	6	13	3.46573590279973	NA	3.02658834002614	3.13093277016658	-0.104344430140438	0.568175598797224	1.09317639824108	0.107708922454661	0.183648207281914	0.0954506796051657	0.787618994815758	NA	NA	0.673748944628364	0.787977245217111	83.8573075986925
a8899	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.18100149307955	0.810158050820032	0.370843442259522	1.09340916056792	1.36809441488671	0.274280747497171	0.339162552897311	0.271065679549779	0.787650856040853	NA	NA	0.165311100078553	0.627182851673084	83.8573075986925
a8900	loss_cnaOV87, loss_cnaOV88	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.10435486155056	2.75622285091368	0.348132010636881	0.34934462215363	1.27436176204473	0.28201379779931	0.996528895995954	0.273181463070816	0.787664751383992	NA	NA	0.0963844821068577	0.289171386606738	83.8573075986925
a8901	loss_cnaOV1	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	1.07703260941977	0.847758172037844	0.229274437381925	1.84730538925391	1.20125168328113	0.182730408381179	0.124112904512516	0.190862947850928	0.787708019357578	NA	NA	0.84566726546959	0.851403307928728	83.8573075986925
a8902	loss_cnaOV54	328	SNX-2112	HSP90	10	22	0.940007258491471	NA	0.869992793292643	0.617129192116405	0.252863601176238	2.32426257927856	2.32757825626963	0.108684490143238	0.10879304405216	0.108638066408774	0.787714860706095	NA	NA	0.946112505509501	0.778888188690658	83.8573075986925
a8903	loss_cnaOV44	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.12636491273995	5.19746498418758	-0.0711000714476304	0.685752655295515	0.78355126860037	0.0914571278657697	0.103681802612913	0.0907408031827119	0.787729259545389	NA	NA	0.33602114938399	0.878497405643616	83.8573075986925
a8904	loss_cnaOV87, loss_cnaOV88	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.51107205715358	2.3813741927237	0.129697864429874	1.41900834082871	0.906784880131956	0.136586091055019	0.0914003538232407	0.143030466510425	0.787796427379392	NA	NA	0.736092604604279	0.88999283915288	83.8573075986925
a8905	ARID1A_mut	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	4.34971651084861	4.90745026789836	-0.557733757049754	1.2201825949965	1.66284123584285	0.355254541593355	0.457090405433423	0.335410107127308	0.787850916730238	NA	NA	0.124823725751205	0.44692380758944	83.8573075986925
a8906	loss_cnaOV43_(NF1)	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.90095849182038	1.52911848579141	0.371840006028973	1.62840362792885	1.22077083395389	0.293883375440725	0.228346338494659	0.304594437945934	0.787954476584298	NA	NA	0.166868270330065	0.73571759274879	83.8573075986925
a8907	loss_cnaOV44	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.90095849182038	1.52911848579141	0.371840006028973	1.62840362792885	1.22077083395389	0.293883375440725	0.228346338494659	0.304594437945934	0.787954476584298	NA	NA	0.166868270330065	0.73571759274879	83.8573075986925
a8908	gain_cnaOV4_(KRAS)	279	BIX02189	MAP2K5 (MEK5)	8	24	2.99573227355399	NA	4.49349626643043	4.41041193969298	0.0830843267374561	0.688880701677855	0.758698266263313	0.111823602964717	0.120607714129738	0.109509050477546	0.788151489645869	NA	NA	0.52644354548219	0.777937917561965	83.8573075986925
a8909	SMAD4_mut	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-3.81224470924374	-4.18881462564941	0.376569916405673	0.131697411555969	2.45304744178907	0.159288299594538	2.85935700600795	0.153511061380464	0.788241099193232	NA	NA	0.928434032071643	0.43780552459292	83.8573075986925
a8910	loss_cnaOV33_(ZFHX3)	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.77457789824496	3.53180993046105	0.242767967783918	1.74250276809866	0.78343237203467	0.26359706334269	0.139321424463971	0.309877376082149	0.78824636395737	NA	NA	0.144801723850524	0.800391799003098	83.8573075986925
a8911	loss_cnaOV36	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.07304421838742	2.33889322594648	-0.265849007559056	0.871998826843431	1.48684103234328	0.182844400509147	0.304873125255695	0.178801231453826	0.788315873669547	NA	NA	0.821834121806132	0.671710294303834	83.8573075986925
a8912	loss_cnaOV81_(RB1)	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	4.89394110625708	4.78094635453242	0.112994751724656	0.90721910153067	0.636586378241228	0.169002648343719	0.124550675282311	0.177501051839721	0.788638987991178	NA	NA	0.763262399422619	0.823399201962853	83.8573075986925
a8913	TP53_mut	196	Phenformin	AAPK1 (AMPK) agonist	21	10	8.29404964010203	NA	8.8174040427552	8.63172818005285	0.185675862702345	1.91332558320162	1.18749314134784	0.107879461266469	0.0970435269002407	0.156359524309839	0.788740461747575	NA	NA	0.922203202370345	0.743493719615124	83.8573075986925
a8914	loss_cnaOV44	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	1.63820215875929	1.41122469277745	0.226977465981846	1.69274570130953	1.812095580119	0.125810761401425	0.134088342865826	0.125256895095423	0.788756208434402	NA	NA	0.616491308678468	0.843035307167032	83.8573075986925
a8915	gain_cnaOV95_(MECOM)	229	LY317615	PRKCB (PKCbeta)	9	23	2.99573227355399	2.32630161961136	2.89078596645543	2.69354464116218	0.197241325293244	2.24057874222002	1.44060730510713	0.116618171604309	0.088031418658294	0.136915399910857	0.788852250978651	NA	NA	0.323727559977098	0.81107895576446	83.8573075986925
a8916	loss_cnaOV16, loss_cnaOV17	345	KIN001-270	CDK9	6	26	2.99573227355399	NA	5.16568277247028	5.19659548633993	-0.0309127138696494	0.88046813131165	0.755358210171044	0.0397535459001566	0.0351094068829024	0.0409245751928076	0.789136392753346	NA	NA	0.336029333299613	0.938913152233242	83.8573075986925
a8917	NF1_mut	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	2.7288490226379	2.71420541550591	0.0146436071319926	0.498353750327569	0.581918635950995	0.0255066333749862	0.0293839609361169	0.0251643549927929	0.789245175389505	NA	NA	0.137522829750739	0.959548184556892	83.8573075986925
a8918	loss_cnaOV55	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	5.1343772194364	4.66102516180497	0.473352057631436	1.84863931114171	1.51391131074482	0.299941425120182	0.256054306958936	0.312668287945186	0.789265129616589	NA	NA	0.124834846939914	0.660949924663294	83.8573075986925
a8919	loss_cnaOV70	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.35793845280024	2.4481051698069	-0.0901667170066593	0.947827830362054	1.50037921120255	0.0613371396662104	0.0951298475507067	0.0600959519656307	0.789301855317828	NA	NA	0.242460134188837	0.89214520964421	83.8573075986925
a8920	loss_cnaOV54	207	AS601245	JNK 	5	13	2.07944154167984	NA	1.83019235239561	2.05626986015873	-0.226077507763124	0.722361924523485	1.07321407269953	0.226725391876128	0.312969856367026	0.210654624752036	0.789346073917034	NA	NA	0.483660728061811	0.616947772852331	83.8573075986925
a8921	gain_cnaOV94	294	MPS-1-IN-1	MPS1	7	24	2.99573227355399	NA	4.29839009331127	4.27960818127969	0.0187819120315806	0.821213576280826	0.827210620458084	0.022739123875474	0.0228709224665301	0.0227051147157417	0.789410634824123	NA	NA	0.319377032720093	0.958671212023944	83.8573075986925
a8922	loss_cnaOV55	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-5.05895866696706	-4.54613400573606	-0.512824661230995	0.922474452392769	2.247374482001	0.247031479276917	0.55592288751282	0.228188343926727	0.789420822492584	NA	NA	0.354099970012869	0.501189901322773	83.8573075986925
a8923	loss_cnaOV16, loss_cnaOV17	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.87113430297761	1.51582673575678	0.355307567220827	1.33092330580256	1.25273505925598	0.281053085707957	0.266963216942522	0.283625467807895	0.789447843631934	NA	NA	0.166879044633582	0.648529473700302	83.8573075986925
a8924	loss_cnaOV41	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.87113430297761	1.51582673575678	0.355307567220827	1.33092330580256	1.25273505925598	0.281053085707957	0.266963216942522	0.283625467807895	0.789447843631934	NA	NA	0.166879044633582	0.648529473700302	83.8573075986925
a8925	loss_cnaOV42	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.87113430297761	1.51582673575678	0.355307567220827	1.33092330580256	1.25273505925598	0.281053085707957	0.266963216942522	0.283625467807895	0.789447843631934	NA	NA	0.166879044633582	0.648529473700302	83.8573075986925
a8926	loss_cnaOV87, loss_cnaOV88	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.07998741592768	2.79758322537997	0.282404190547716	0.418527875491591	1.45088721509874	0.200877949859734	0.674755988991205	0.194642414385392	0.789478977058936	NA	NA	0.629193521312906	0.455097506162684	83.8573075986925
a8927	loss_cnaOV58	1371	PLX4720 (rescreen)	BRAF	5	28	2.30258509299405	NA	4.49258183489407	4.53465038028237	-0.0420685453883012	1.32330290224649	0.937957347116418	0.042233613200484	0.031790563836053	0.0448512349923303	0.789764660711155	NA	NA	0.327852683537998	0.948484605534019	83.8573075986925
a8928	loss_cnaOV59	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.60347536171904	3.47274204879793	0.130733312921113	0.631004429208416	1.16593658886032	0.11646790850762	0.20718287680661	0.112127292487581	0.789782791663046	NA	NA	0.728176741852854	0.746080275313476	83.8573075986925
a8929	PIK3CA_mut	310	YM201636	FYV1	6	26	1.63315443905142	NA	2.51124589515528	2.32130211228797	0.189943782867308	0.986016772955491	0.846692689304202	0.217960021422883	0.192637476437616	0.224336155569502	0.789871441665504	NA	NA	0.652216471307461	0.676185144730139	83.8573075986925
a8930	loss_cnaOV59	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	1.79662929681865	1.72967247667646	0.0669568201421902	1.79674079438896	1.70557128450963	0.0390508486461009	0.0372657093061446	0.0392577083997055	0.789873956635276	NA	NA	0.231509209846664	0.94751687321921	83.8573075986925
a8931	loss_cnaOV52, loss_cnaOV53	1129	PF-4708671	RPS6KB1 (p70S6KA)	9	23	2.30258509299405	NA	4.39370027093874	4.12007353946262	0.273626731476113	0.826267050116434	1.02190551337983	0.281050168120208	0.331160163578536	0.267761283106424	0.789918308072181	NA	NA	0.0492106454283351	0.442173630544135	83.8573075986925
a8932	loss_cnaOV54	1004	Vinblastine	Microtubules	10	21	-2.30258509299405	NA	-3.22093035794017	-3.36007265646612	0.139142298525945	1.37234076677246	2.01142751249749	0.0757426912979827	0.101390486892834	0.0691758950603092	0.789978614544747	NA	NA	0.141474085252762	0.823478466179229	83.8573075986925
a8933	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.18206159082057	5.00356953991162	0.178492050908953	1.90495627131372	1.07114865116133	0.148779516660203	0.0936987654765739	0.16663611601941	0.790019621039835	NA	NA	0.802569729298028	0.887776982489421	83.8573075986925
a8934	SMAD4_mut	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.11492824246142	3.00133209448499	0.113596147976424	2.11561284644649	0.97669365419952	0.104189337462526	0.0536942041012972	0.116306835298859	0.790086645591429	NA	NA	0.436848584551734	0.934770170631876	83.8573075986925
a8935	gain_cnaOV26	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	2.92858036755663	2.84834014466434	0.0802402228922863	0.471938677186911	1.11180269851648	0.0742282295928647	0.170022561767081	0.0721712791301494	0.790225156068984	NA	NA	0.309236124368549	0.824028975687592	83.8573075986925
a8936	RB1_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	0.977311765539668	1.1869300939339	-0.209618328394231	0.654207802361964	1.54508061999861	0.139409251830028	0.320415512681782	0.135668214124917	0.7902969411321	NA	NA	0.813978478114359	0.676090390340885	83.8573075986925
a8937	gain_cnaOV4_(KRAS)	204	Tipifarnib	Farnesyl-transferase (FNTA)	6	13	2.77258872223978	NA	2.08798245652223	1.75585073966698	0.332131716855244	1.30496527911736	1.81359366651477	0.197690578656858	0.254513834329667	0.183134581349476	0.790329695944101	NA	NA	0.350241012012762	0.657561854157591	83.8573075986925
a8938	loss_cnaOV20	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	2.10740314555213	1.90822218043227	0.199180965119865	0.763363148852739	1.41991072806206	0.14743942059452	0.260925570508891	0.140277104175214	0.790382708279437	NA	NA	0.839857011933886	0.658361505912744	83.8573075986925
a8939	loss_cnaOV55	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.43585751967855	5.19460487661068	0.241252643067866	0.856785941362151	0.721387413153245	0.323541058603157	0.281578666760467	0.33442868376831	0.790422525395396	NA	NA	0.129577411902058	0.630300918504129	83.8573075986925
a8940	loss_cnaOV70	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.13052016318986	3.96425825424958	0.166261908940283	0.809491327900744	0.76299396315275	0.217000660075575	0.205390599268618	0.217907240384022	0.790566253715045	NA	NA	0.52767470884731	0.76124507359522	83.8573075986925
a8941	loss_cnaOV21, loss_cnaOV22	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.69944677626354	4.06716332564237	-0.36771654937883	1.23666165757221	1.52330140902277	0.244185451269365	0.297346123029903	0.241394478598118	0.790660992179184	NA	NA	0.332168731236585	0.668481298191041	83.8573075986925
a8942	loss_cnaOV35	1031	Elesclomol	HSP70	5	26	-1.6094379124341	NA	-3.91270477640996	-4.08805526649113	0.175350490081171	1.37915362282599	1.55967800248984	0.114157504062233	0.127143551797997	0.112427366290507	0.790698253480204	NA	NA	0.864795763790488	0.807258100781488	83.8573075986925
a8943	ARID1A_mut	1502	Bicalutamide	ANDR (androgen receptor)	9	23	2.30258509299405	NA	4.42253156814018	4.55280739395772	-0.130275825817542	0.341098319963115	0.671074388025405	0.216742571432339	0.381930423555381	0.194130230779438	0.790736063828877	NA	NA	0.616847317084793	0.476035813009726	83.8573075986925
a8944	loss_cnaOV1	290	KIN001-260	IKK	3	28	2.99573227355399	NA	5.01227855249802	4.83288583569975	0.179392716798265	1.12956309274802	0.889271983161741	0.197593471459097	0.1588160218318	0.201729864647762	0.790774644396744	NA	NA	0.667014154734925	0.812198431764197	83.8573075986925
a8945	loss_cnaOV20	308	XL-880	MET	5	27	1.63315443905142	NA	0.087066625470628	0.283845025752466	-0.196778400281838	0.638981711688637	1.01840728045239	0.201540008656308	0.307956232052106	0.193221714002698	0.790786145130352	NA	NA	0.370702089002569	0.585036478656196	83.8573075986925
a8946	gain_cnaOV72_(ASXL1)	192	LFM-A13	BTK	4	15	2.77258872223978	NA	4.80450740659065	4.703906025054	0.10060138153665	0.629388013078213	0.712525564181158	0.144009718147854	0.159840002424941	0.14118985562611	0.790804697838323	NA	NA	0.95730945144038	0.79306308140616	83.8573075986925
a8947	loss_cnaOV20	1052	RO-3306	CDK1	5	28	1.6094379124341	NA	3.39927898919919	3.49652328010917	-0.0972442909099867	1.13356296584533	0.874135892443933	0.106654687673186	0.0857864043198239	0.111246193813308	0.790910532454471	NA	NA	0.795204316949066	0.862605036040441	83.8573075986925
a8948	gain_cnaOV50	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.90679030207726	3.88927054516087	0.0175197569163994	0.768725019345549	1.5796553299173	0.0115173305169131	0.0227906682825476	0.0110908731699823	0.790918225162364	NA	NA	0.0715708271434373	0.976527888005655	83.8573075986925
a8949	gain_cnaOV49	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.817270242482938	-0.815238454158037	-0.00203178832490059	0.920810912220999	0.804910419794651	0.00249779154998358	0.0022065206851208	0.00252424154903962	0.790995794745044	NA	NA	0.0802636007091904	0.997358119001895	83.8573075986925
a8950	PIK3CA_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	6	26	2.30258509299405	NA	3.7366050659545	4.30328320962931	-0.566678143674805	0.687588561551262	0.999821835834925	0.593442803189564	0.824152953324773	0.566779123404108	0.791158688455634	NA	NA	0.0492138293765537	0.127292311572411	83.8573075986925
a8951	gain_cnaOV72_(ASXL1)	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.52422298009636	4.33745853123331	0.186764448863042	1.05197928101541	1.07148745669715	0.174724704524997	0.177536242617601	0.174303905935345	0.791163892505901	NA	NA	0.354243109760922	0.729372672992289	83.8573075986925
a8952	gain_cnaOV19	154	CHIR-99021	GSK3B	3	16	0.940007258491471	NA	3.55885090224967	3.27468336134358	0.284167540906092	0.4014247549967	1.03851236300214	0.288441828241303	0.707897401365862	0.273629425156401	0.791175647842247	NA	NA	0.193815370116515	0.436734849221906	83.8573075986925
a8953	PIK3CA_mut	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.21724141473294	2.10992277648836	0.107318638244579	1.41458830784759	1.36619599470661	0.0778543852291101	0.0758656335905062	0.0785528860137126	0.791273931217642	NA	NA	0.893305168469677	0.88834660881611	83.8583571727327
a8954	loss_cnaOV56	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-2.34537585080058	-2.29354246691113	-0.0518333838894423	2.18564742466198	1.58306151124273	0.0318253979778158	0.0237153455331244	0.0327424951723779	0.791686560610232	NA	NA	0.126126717987215	0.971382570062748	83.8927168433728
a8955	loss_cnaOV81_(RB1)	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-3.2800289723555	-3.73521850597247	0.45518953361697	1.83796019100069	1.73039526430335	0.261900109957753	0.247660170141738	0.263055235417688	0.791849870076708	NA	NA	0.247628559964654	0.71566071423969	83.8959974528412
a8956	loss_cnaOV81_(RB1)	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.60039035823287	4.50215848687001	0.0982318713628603	0.463943515276445	0.95472485170531	0.105712367889124	0.211732394415143	0.102890242343017	0.792002690795244	NA	NA	0.530594405943517	0.775603938052355	83.8959974528412
a8957	loss_cnaOV83	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-2.28562492578681	-2.30050989038578	0.0148849645989708	1.83088595905471	1.59662087448398	0.0091389272561277	0.00812992449112227	0.00932279217743633	0.79210391271002	NA	NA	0.126128482308316	0.98703224022103	83.8959974528412
a8958	TP53_mut	298	OSI-930	KIT, VEGFR, PDGFR	22	10	2.32630161961136	NA	4.46829059712633	4.41477227953296	0.0535183175933795	1.05575581214757	0.824300147442412	0.0539496029475443	0.0506919469233278	0.0649257649163753	0.792167164866153	NA	NA	0.0321060077840986	0.877916988007417	83.8959974528412
a8959	loss_cnaOV39	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	4.80139169067656	4.74613770367409	0.0552539870024704	1.99977424980656	1.44220224084034	0.0347275088215563	0.0276301122528282	0.038312232111271	0.792290403643465	NA	NA	0.12485836517047	0.956735956584851	83.8959974528412
a8960	loss_cnaOV16, loss_cnaOV17	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	5.16678679171616	4.68453287060448	0.48225392111168	2.3421132805939	1.44887127263625	0.305149917761017	0.205905463714118	0.332848010875536	0.792458706750205	NA	NA	0.124859662675018	0.759520915454774	83.8959974528412
a8961	gain_cnaOV51_(MYC)	344	THZ-2-49	CDK9	8	24	2.99573227355399	NA	2.91248688774689	2.47881785141596	0.433669036330928	1.64707798858914	2.5200911358163	0.18488358376205	0.263295994078825	0.172084663989921	0.792576967814682	NA	NA	0.388376018190892	0.583368249090749	83.8959974528412
a8962	loss_cnaOV84	1061	SB590885	BRAF	6	27	1.6094379124341	NA	3.74760668461661	3.96752496639835	-0.219918281781734	1.94883398944935	1.12106213282347	0.17034897274664	0.112846082823028	0.196169574676343	0.792629687539924	NA	NA	0.575029579022835	0.798936458107324	83.8959974528412
a8963	loss_cnaOV21, loss_cnaOV22	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	3.96309838407823	3.82920391322374	0.133894470854492	0.57628884864031	0.887503503603441	0.153762403421649	0.232339166670327	0.150866413834823	0.792757330077703	NA	NA	0.924120915152122	0.741123094065677	83.8959974528412
a8964	gain_cnaOV50	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	3.72655700602452	3.85721325947754	-0.130656253453024	0.938664837353741	0.862969141534062	0.150079165056514	0.139193723098616	0.15140315819493	0.792801015293324	NA	NA	0.924120953320239	0.806090584232026	83.8959974528412
a8965	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	2.57442211934385	2.26403509922611	0.310387020117739	1.0278975794062	1.26552859692594	0.250324628431298	0.301962983799459	0.24526274702262	0.792964968342125	NA	NA	0.393503219933457	0.673465774697031	83.8959974528412
a8966	loss_cnaOV16, loss_cnaOV17	155	AP-24534	ABL	3	16	-0.669430653942629	NA	0.913618172328483	0.765100716053685	0.148517456274797	1.91816284553828	1.16152798183535	0.116568077242156	0.0774269278649904	0.127863864321307	0.79301836013718	NA	NA	0.587660207759339	0.907331287527162	83.8959974528412
a8967	loss_cnaOV55	1248	FK866	NAMPT	7	25	0	NA	-1.0629850766004	-1.88906209757562	0.826077020975225	2.42721933029172	2.8347161854549	0.299516228570851	0.340338843987347	0.291414366353103	0.793076213919574	NA	NA	0.0456045737561214	0.459727633450076	83.8959974528412
a8968	loss_cnaOV39	1527	GDC0941 (rescreen)	PI3K	8	23	1.38629436111989	NA	0.446632916481739	0.359898072729147	0.0867348437525914	0.749724460558879	0.965533772162846	0.0944722894067635	0.115688960832271	0.0898309787324175	0.793139482463387	NA	NA	0.910131043206413	0.797797147655487	83.8959974528412
a8969	loss_cnaOV21, loss_cnaOV22	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	4.81250188235722	4.9501791656973	-0.137677283340076	0.781797275776714	0.827383378872503	0.166979030742386	0.176103559843303	0.166400832861415	0.793154184169458	NA	NA	0.946244403106923	0.794907389191733	83.8959974528412
a8970	gain_cnaOV26	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.2156029629033	5.04611509673579	0.169487866167509	0.0763992546943495	0.642025062720256	0.273116990489285	2.21844920929634	0.263989485783297	0.793164660810256	NA	NA	0.112334151952152	0.192931586047411	83.8959974528412
a8971	loss_cnaOV33_(ZFHX3)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	2.9215123988084	2.7808115906665	0.140700808141901	1.59247121834291	0.876092674298623	0.145224083297384	0.088353752658909	0.160600370565297	0.793239843891444	NA	NA	0.966361080030547	0.872762509280679	83.8959974528412
a8972	loss_cnaOV39	1170	CCT018159	HSP90	10	23	2.30258509299405	NA	3.89406428945228	3.6083916627464	0.285672626705888	1.41650703375114	1.14007173514798	0.23286736340619	0.201673990950388	0.250574255898737	0.793309089097982	NA	NA	0.200337303550575	0.581922135412484	83.8959974528412
a8973	gain_cnaOV18_(CCNE1)	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	2.86245866653444	2.66804252087947	0.194416145654972	1.33512734702383	1.35041406102735	0.144254627550768	0.145616181174291	0.143967803110008	0.793501385770658	NA	NA	0.941675330114551	0.807032892059086	83.9069443848949
a8974	RB1_mut	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	3.72886507374011	3.69156853054899	0.037296543191125	1.31959238035553	1.22805670802659	0.0302200103006581	0.0282636848668952	0.0303703753640645	0.793647264601448	NA	NA	0.20033900740134	0.966222011323459	83.9069443848949
a8975	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1001	AICAR	AAPK1 (AMPK) agonist	4	27	7.60090245954208	NA	8.65959843746232	8.76291272827712	-0.103314290814795	0.878476269081556	1.28067485119935	0.0829761980968278	0.117606239862131	0.0806717573301619	0.793742152538898	NA	NA	0.532098170174445	0.845368456263154	83.9069443848949
a8976	loss_cnaOV41	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	4.87748313191885	4.85683809720513	0.0206450347137217	0.592046591888684	0.630444952550039	0.0330076885451017	0.0348706250429753	0.0327467681836712	0.793910990655555	NA	NA	0.0507613387940617	0.945863245791058	83.9069443848949
a8977	loss_cnaOV35	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.487162793376215	0.366743253004424	0.120419540371791	1.01304017580486	0.906379304010912	0.131177674906733	0.118869461693479	0.132857778017338	0.793942023899458	NA	NA	0.910131929310994	0.833866492676311	83.9069443848949
a8978	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1194	SB-505124	TGFR1 (ALK5)	7	25	2.30258509299405	NA	4.50287028423488	4.61239592742803	-0.109525643193152	1.26713782833163	0.854014354402796	0.115156247367328	0.0864354616714098	0.12824801202521	0.794071244923595	NA	NA	0.943432672533733	0.835129370654875	83.9069443848949
a8979	gain_cnaOV50	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.493733642021472	0.576368748782118	-0.0826351067606458	0.528115612443249	1.27842478254162	0.0676032478849369	0.156471622526641	0.064638223452114	0.794132275421764	NA	NA	0.433346933028326	0.823687268118025	83.9069443848949
a8980	loss_cnaOV39	179	5-Fluorouracil	DNA antimetabolite	9	22	3.46573590279973	NA	4.19746068134784	3.78195372510543	0.415506956242407	1.91875235627913	1.63577252921031	0.241785169199363	0.216550590743332	0.254012675248311	0.794158109800345	NA	NA	0.149366514831604	0.578133356534223	83.9069443848949
a8981	BRCA1_mut	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.15194912805978	2.32017523094906	-0.16822610288928	1.46012714287058	1.24164109685608	0.132880764582047	0.115213324887962	0.135486899809647	0.794219080168611	NA	NA	0.845333550669486	0.83827954773942	83.9069443848949
a8982	loss_cnaOV21, loss_cnaOV22	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.242378257456286	0.28499865601237	-0.0426203985560836	0.572534271453571	1.17735970556881	0.0371259338369868	0.0744416547290303	0.0361999806469447	0.794384778974418	NA	NA	0.14875569908635	0.919128077733571	83.9069443848949
a8983	loss_cnaOV1	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.05636873341631	5.9363078098133	0.12006092360301	0.514690676160858	0.718774144667769	0.169724649863663	0.233268114547089	0.167035673853438	0.794546813355976	NA	NA	0.909149584915915	0.737436107911232	83.9069443848949
a8984	gain_cnaOV94	1066	AZD6482	PI3Kbeta	7	26	1.6094379124341	NA	2.64386961582769	2.3078331924873	0.336036423340389	1.2379196522302	1.32672584931249	0.25651488938632	0.271452531458722	0.253282487496962	0.794557021152614	NA	NA	0.11173955979011	0.544210825569977	83.9069443848949
a8985	loss_cnaOV20	1026	17-AAG	HSP90	5	28	0	NA	0.0207699624610915	-0.62933253699561	0.650102499456701	2.50881334986409	2.27099616642198	0.28227739241483	0.259127487300687	0.286263142610653	0.79460274008165	NA	NA	0.0625080133941059	0.610591450253723	83.9069443848949
a8986	BRCA1_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	2.04504633445506	1.69540805769213	0.349638276762932	1.54229847839173	1.72777806074196	0.204382260220523	0.226699488887213	0.202362956624641	0.794713808888443	NA	NA	0.231534742673219	0.696426297946187	83.9069443848949
a8987	loss_cnaOV1	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.31541437437677	3.41969334578741	-0.104278971410644	1.64651348061808	1.19584414954106	0.08470855088009	0.0633332023321783	0.0872011385853789	0.794912115228057	NA	NA	0.329202913005794	0.923800512687077	83.9069443848949
a8988	loss_cnaOV56	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.86582098118332	5.71205918721106	0.153761793972253	1.23503128095527	0.535382608801117	0.2530523100577	0.124500323468181	0.287199829513648	0.794948517938891	NA	NA	0.194579485042088	0.850008043802305	83.9069443848949
a8989	gain_cnaOV94	304	SB52334	ALK5	7	25	2.99573227355399	NA	4.39116164270908	4.35977454979271	0.0313870929163764	1.22347172557859	1.02950897231309	0.029303192948066	0.02565412200395	0.0304874398965715	0.795136523087023	NA	NA	0.354265584840721	0.9519866292889	83.9069443848949
a8990	loss_cnaOV54	281	CH5424802	ALK	10	22	1.63315443905142	NA	3.8807487168233	3.94890426391414	-0.0681555470908353	0.801879208254503	0.704263909776811	0.0927398429264649	0.0849947802477551	0.096775578223843	0.795201579234244	NA	NA	0.956016014760015	0.82010894662318	83.9069443848949
a8991	loss_cnaOV82	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.48996737013021	2.52920313654817	-0.0392357664179643	0.638463203105161	1.07266670777499	0.0374516690700218	0.0614534498263039	0.0365777795969358	0.795278006260164	NA	NA	0.198091159560911	0.931179047374879	83.9069443848949
a8992	loss_cnaOV83	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	1.1582251489873	1.37259211533788	-0.214366966350584	1.47433741226334	1.48945525664536	0.144117243472738	0.145398851421329	0.143923065425539	0.795280713679663	NA	NA	0.858044867163544	0.834450254113762	83.9069443848949
a8993	loss_cnaOV84	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	1.1582251489873	1.37259211533788	-0.214366966350584	1.47433741226334	1.48945525664536	0.144117243472738	0.145398851421329	0.143923065425539	0.795280713679663	NA	NA	0.858044867163544	0.834450254113762	83.9069443848949
a8994	KRAS_mut	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.5597736248253	-4.06171314990655	0.50193952508125	3.05000913689646	1.60172115147269	0.273907744874062	0.164569843089716	0.313375099417115	0.795358107502825	NA	NA	0.593852809121487	0.804914699370892	83.9069443848949
a8995	loss_cnaOV38	1022	AZD7762	CHEK1, CHEK2	8	23	0.693147180559945	NA	-0.763786225131134	-0.833399897514121	0.0696136723829864	0.792183314334868	0.819282759148662	0.0856441884818095	0.0878757114966949	0.0849690434781317	0.79566741789194	NA	NA	0.0802801155083554	0.835344420706105	83.9302435297944
a8996	gain_cnaOV50	312	AV-951	VEGFR	4	28	-2.05572501506252	NA	0.668973377733568	0.635686230467249	0.0332871472663184	0.602299747467924	0.624403760794737	0.0534966444177638	0.0552667461778924	0.0533102927246158	0.796179475854723	NA	NA	0.0155769948598411	0.923005515157996	83.9650388368081
a8997	gain_cnaOV51_(MYC)	192	LFM-A13	BTK	5	14	2.77258872223978	NA	4.65716342604143	4.74934306228325	-0.0921796362418137	0.730531164147099	0.688478649383961	0.131948879184171	0.126181661735724	0.133888881411638	0.796277372842431	NA	NA	0.957314559423127	0.813131877142422	83.9650388368081
a8998	loss_cnaOV54	167	OSU-03012	PDPK1 (PDK1)	6	13	2.77258872223978	NA	2.2915202223901	2.32297743163913	-0.0314572092490324	0.973339264809125	1.34285029022876	0.0252546253603073	0.0323188536478093	0.0234257008975092	0.796305970577711	NA	NA	0.393536822942755	0.954795334022554	83.9650388368081
a8999	loss_cnaOV1	1264	SGC0946	Q8TEK3 (DOT1L)	3	30	-0.693147180559945	NA	2.12234965786443	2.1146084042679	0.007741253596528	0.351337984406918	0.575377527402997	0.0137349480329862	0.0220336369538743	0.0134542161065425	0.79635125423418	NA	NA	0.0432949254555782	0.974969848220964	83.9650388368081
a9000	loss_cnaOV42	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	3.52484902773369	3.35370850636361	0.171140521370074	1.10327896458145	1.73394567422029	0.101775046113473	0.155119898832657	0.0987000480548682	0.796721225468527	NA	NA	0.631528453620894	0.799538787068767	83.9757914237263
a9001	loss_cnaOV57_(ZNRF3)	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.48145316638279	4.5347347295464	-0.0532815631636101	1.52774838014633	0.921055942392777	0.0534927773147482	0.0348758760644254	0.0578483463503769	0.796886582242477	NA	NA	0.327891727735705	0.949642358965969	83.9757914237263
a9002	loss_cnaOV84	299	OSI-027	MTORC1/2	6	26	2.99573227355399	NA	1.67920443045027	1.49686375321231	0.182340677237954	1.22798652821348	2.04534874955915	0.0943172097742661	0.148487522500129	0.0891489420947189	0.796906661396942	NA	NA	0.783693969238024	0.781086496455913	83.9757914237263
a9003	loss_cnaOV81_(RB1)	1069	EHT 1864	Rac GTPases	4	29	2.30258509299405	NA	4.43806062016846	4.20053326918853	0.237527350979928	0.5330707504495	1.0195571673344	0.241621254295977	0.44558316279713	0.232971096266173	0.796992734611014	NA	NA	0.21180860140133	0.492429189038351	83.9757914237263
a9004	loss_cnaOV81_(RB1)	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	3.24201810843754	3.25243142249693	-0.0104133140593974	0.985909561528597	1.10742585847797	0.00950223293849467	0.0105621392323776	0.00940317040610675	0.797050242916662	NA	NA	0.0636660233509486	0.985382840533702	83.9757914237263
a9005	loss_cnaOV54	1373	Dabrafenib	BRAF	11	21	2.30258509299405	NA	3.81740242018251	3.55666762330825	0.260734796874265	2.63816685078263	1.66195726483692	0.127814613632333	0.0988318069408374	0.156884176501283	0.797172521734873	NA	NA	0.748666148902329	0.769807139317178	83.9757914237263
a9006	PIK3R1_mut	155	AP-24534	ABL	3	16	-0.669430653942629	NA	0.740817599695819	0.79750082342231	-0.0566832237264908	1.48261951226114	1.24491477567595	0.0444510868445116	0.038231807458168	0.0455318105576452	0.797206043870662	NA	NA	0.587693837576855	0.954911698356715	83.9757914237263
a9007	ARID1A_mut	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-4.43906467846068	-4.09823802073029	-0.34082665773039	1.01847075363999	1.42571000947417	0.254009190072082	0.334645503086156	0.239057490980296	0.797439827227544	NA	NA	0.220057554015604	0.471714052274958	83.9757914237263
a9008	loss_cnaOV54	288	KIN001-055	JAK3, MNK1	10	22	2.32630161961136	NA	3.75742161372814	3.82079054029554	-0.0633689265674042	1.09424236270687	1.01475522821593	0.060976223993115	0.0579112349577166	0.0624474994613379	0.79751150842071	NA	NA	0.718589163032419	0.878502909173579	83.9757914237263
a9009	NF1_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	4	28	1.65632149833295	0.0237165266173161	4.48488863704792	4.44722629577994	0.0376623412679873	0.519138218363811	0.565348056984877	0.067146456934432	0.0725478108444591	0.0666179724201206	0.797558116179639	NA	NA	0.367306482104487	0.899609824581033	83.9757914237263
a9010	ARID1A_mut	308	XL-880	MET	8	24	1.63315443905142	NA	0.490626545833077	0.173922352333546	0.316704193499531	0.618147340342205	1.0526567577218	0.326883133572331	0.512344182091286	0.300861787260032	0.79759158247816	NA	NA	0.370740193909619	0.313155142807591	83.9757914237263
a9011	gain_cnaOV26	197	Bryostatin 1	PRKC	3	16	-4.8283137373023	NA	-2.19300900275747	-2.35116421543799	0.158155212680519	0.93828817362225	0.737200371683978	0.207114840355535	0.168557184377549	0.214534906323022	0.797636602964597	NA	NA	0.677156145478647	0.803589582147808	83.9757914237263
a9012	loss_cnaOV55	235	QL-XII-47	BTK, BMX	7	25	2.32630161961136	NA	1.62258989313335	1.54924456118467	0.0733453319486894	1.40217450958809	1.68742733583939	0.0448769718799668	0.0523082764999313	0.0434657720607593	0.797671498277642	NA	NA	0.0803030732312353	0.909103741641509	83.9757914237263
a9013	loss_cnaOV58	1021	Axitinib	PDGFR, KIT, VEGFR	5	25	0.693147180559945	NA	2.5296335520322	2.52440876148121	0.00522479055098835	0.912359752612579	1.0685986252425	0.00498688505251743	0.00572667803026925	0.00488938543206778	0.797760252438232	NA	NA	0.198104767154934	0.991294105107525	83.9757914237263
a9014	loss_cnaOV70	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	2.30258509299405	NA	1.93731348535912	2.19135086816531	-0.254037382806191	1.03661827580893	1.32886602951785	0.193802641585599	0.245063577147481	0.191168543076056	0.797780804770248	NA	NA	0.688118272837684	0.723738390890463	83.9757914237263
a9015	gain_cnaOV48_(SOX17)	1028	VX-702	p38	3	28	0.693147180559945	NA	3.24316416661029	3.33594833467277	-0.0927841680624821	0.672671155609621	0.949584543791071	0.0994333724537822	0.137933918064905	0.0977102762141173	0.798073145951031	NA	NA	0.52031573672036	0.842501761929155	83.9828391437011
a9016	gain_cnaOV18_(CCNE1)	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.76190940094466	1.59341206313725	0.16849733780741	0.304885878466504	0.716921155760399	0.245290128256044	0.552657075017404	0.23502910529777	0.798106618801791	NA	NA	0.211364813670652	0.430089297201036	83.9828391437011
a9017	loss_cnaOV36	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.17105274922276	0.811152925205712	0.359899824017046	1.33753445135597	1.35333162097667	0.26613549429203	0.269077049680616	0.265936167040354	0.79811329521195	NA	NA	0.165360549652274	0.693610879512568	83.9828391437011
a9018	loss_cnaOV58	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.06888792861975	3.00144354905001	0.067444379569741	1.62190337403218	0.983621644252501	0.0618455823582861	0.0415834757172179	0.0685674008536027	0.798235273559675	NA	NA	0.436892468018464	0.932127112805391	83.9839234134904
a9019	loss_cnaOV82	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.271220815971533	-0.203741484469686	0.474962300441218	2.39221900101463	1.54261422143775	0.293982230131322	0.198544656755827	0.307894413159593	0.798365987846137	NA	NA	0.102325942452463	0.766150369643705	83.9839234134904
a9020	gain_cnaOV26	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.25946416383466	-4.17558060116236	-0.0838835626723027	1.15481960411332	1.36306556179838	0.0621275909700516	0.072637806263004	0.0615403726887722	0.798389138967385	NA	NA	0.220062516666494	0.914808514598566	83.9839234134904
a9021	loss_cnaOV36	1061	SB590885	BRAF	3	30	1.6094379124341	NA	4.05654938659904	3.91463886802193	0.141910518577104	1.97403928135716	1.23253167337286	0.10973043336579	0.0718883965062437	0.115137421327893	0.798648658861944	NA	NA	0.575055617964343	0.913208591300884	83.9946712239228
a9022	PIK3CA_mut	157	JNK-9L	JNK	5	14	1.63315443905142	NA	0.184186191487126	-0.108530164991924	0.29271635647905	0.737614255071118	1.08207574256295	0.289350182039904	0.39684205459238	0.270513740365104	0.798668361583166	NA	NA	0.19451087637106	0.518891036421019	83.9946712239228
a9023	loss_cnaOV20	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.79395206459283	5.70046625919428	0.0934858053985499	0.618873369316715	0.455661697180358	0.194504303404659	0.151058051668576	0.205164941396307	0.79889397834585	NA	NA	0.384166422711698	0.760904317496313	83.9996245054131
a9024	loss_cnaOV57_(ZNRF3)	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.41598288679567	3.57554378995282	-0.159560903157151	1.04883993447841	0.956637212492735	0.165133585826423	0.152130842764394	0.166793535807978	0.798946148315764	NA	NA	0.729821956966432	0.788806772449958	83.9996245054131
a9025	loss_cnaOV34	333	T0901317	LXR	5	27	2.32630161961136	NA	4.85076803736065	4.73531169845524	0.11545633890541	1.24581873977272	1.10874542360726	0.102356299256763	0.0926750699917019	0.104132415293114	0.799248372071802	NA	NA	0.00531702812704507	0.85382773629968	83.9996245054131
a9026	loss_cnaOV82	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.55121812028077	1.58157954152235	-0.0303614212415846	1.72759941719359	1.21412370286458	0.0238692643938043	0.0175743409840374	0.0250068598199265	0.799329763697475	NA	NA	0.166948250042367	0.978916932742814	83.9996245054131
a9027	KRAS_mut	1494	SN-38	TOP1	7	25	-2.99573227355399	NA	-4.43792863567122	-4.11218917902055	-0.325739456650671	0.66853606719216	1.46411196387555	0.2425032354528	0.487242906757104	0.22248261382171	0.799484971265533	NA	NA	0.220068213759265	0.408463043645804	83.9996245054131
a9028	loss_cnaOV16, loss_cnaOV17	226	GSK1070916	AURKB	6	26	0.940007258491471	2.32630161961136	2.42861048716309	2.28751435710122	0.14109613006187	0.768533515957356	1.55643358619112	0.0969697686472154	0.183591381679832	0.0906534858369116	0.799542080394523	NA	NA	0.821857470491852	0.751358305830966	83.9996245054131
a9029	PIK3CA_mut	281	CH5424802	ALK	6	26	1.63315443905142	NA	3.86019390165986	3.9431622140148	-0.0829683123549394	0.369846175178605	0.787839565604691	0.112901354248876	0.224331946423057	0.105311177525412	0.799634503005757	NA	NA	0.956018286584658	0.705649475560028	83.9996245054131
a9030	TP53_mut	228	KIN001-102	AKT1	22	10	2.32630161961136	NA	2.81290587026067	2.73595981154137	0.0769460587193018	1.21129797430584	1.29926144285092	0.0621362921109584	0.0635236418713547	0.0592229217165576	0.799654127100336	NA	NA	0.0964297805076504	0.875950544281258	83.9996245054131
a9031	loss_cnaOV35	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	5	28	1.6094379124341	NA	2.31844695892944	2.34845534376301	-0.0300083848335695	1.99057140497048	1.49248798104135	0.0191662859763694	0.0150752616854829	0.0201062824054581	0.799787057570343	NA	NA	0.244478398255017	0.975648295063405	83.9996245054131
a9032	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	294	MPS-1-IN-1	MPS1	7	24	2.99573227355399	NA	4.3602242508515	4.26157321866379	0.0986510321877123	0.540142923615687	0.884243106282112	0.119589804719891	0.182638757029987	0.111565508949796	0.799851870392523	NA	NA	0.319437932141798	0.721953129847273	83.9996245054131
a9033	loss_cnaOV55	1058	GDC0941	PI3K (class 1)	8	25	1.38629436111989	0.693147180559945	1.08523044937787	0.766636096352667	0.318594353025205	0.971638783473808	1.44079265201852	0.236137387979885	0.327893820670851	0.221124359968702	0.799886439511783	NA	NA	0.165368660826833	0.486597519782609	83.9996245054131
a9034	PIK3R1_mut	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	3.7625065375121	3.85545999504951	-0.0929534575374094	0.720793107725034	0.891118653049083	0.106718581355566	0.128959969984714	0.104310977241197	0.799949536695562	NA	NA	0.924127080592489	0.806275247348065	83.9996245054131
a9035	KRAS_mut	341	EX-527	SIRT1	7	24	2.99573227355399	NA	5.65176464041131	5.80876492344605	-0.157000283034741	0.512771161039576	0.578235947187117	0.277722343490348	0.306180017449585	0.271515950882134	0.80004846950319	NA	NA	0.112511632458789	0.503509646774987	83.9996245054131
a9036	MLL2_mut	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	5.98021594364236	5.94392308879069	0.0362928548516681	0.700191451898194	0.70874948239689	0.051246583807949	0.0518327591022134	0.0512068872755023	0.800096696932147	NA	NA	0.909155243846884	0.938402778040063	83.9996245054131
a9037	loss_cnaOV43_(NF1)	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.69357235469796	5.71905509436	-0.0254827396620367	0.561925674156523	0.468279293516946	0.0528886975230378	0.0453489506424271	0.0544178228993475	0.800177369949327	NA	NA	0.384173367253719	0.927606250448295	83.9996245054131
a9038	gain_cnaOV51_(MYC)	1020	Lenalidomide	TNFA	8	23	1.6094379124341	NA	4.57723881622865	4.33825045104951	0.238988365179144	0.703632728185044	0.791058793437883	0.310026504334755	0.339649302265391	0.302112013875123	0.80018589377305	NA	NA	0.0441420577140854	0.437023917555437	83.9996245054131
a9039	gain_cnaOV26	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.25105410768454	2.28746706196636	-0.0364129542818241	2.72807197134344	1.72339494910094	0.0201715252845451	0.0133475050014508	0.0211286184288866	0.800346896884907	NA	NA	0.112275235109366	0.983833074601788	83.9996245054131
a9040	loss_cnaOV21, loss_cnaOV22	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.62030529404967	3.47560788865254	0.144697405397129	0.637684593218698	1.15034033524101	0.128903305485169	0.226910618408973	0.125786605028341	0.800362460876183	NA	NA	0.728210475473797	0.753818387073233	83.9996245054131
a9041	loss_cnaOV70	308	XL-880	MET	3	29	1.63315443905142	NA	0.0569616146373744	0.273388413060607	-0.216426798423232	0.373658797634999	1.00633611244452	0.221524437052081	0.57920969556468	0.215064127925912	0.800397525524069	NA	NA	0.370755505014061	0.477508743879425	83.9996245054131
a9042	loss_cnaOV54	196	Phenformin	AAPK1 (AMPK) agonist	10	21	8.29404964010203	NA	8.63353816849931	8.81654214349498	-0.183003974995669	1.82667260522984	1.67158058728262	0.106322939465631	0.10018433214125	0.109479600557678	0.800658492139673	NA	NA	0.922214536311975	0.79213086064007	84.0177193008788
a9043	loss_cnaOV1	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.37570453630938	1.51032872362151	-0.134624187312126	0.86878586152136	1.76336652945669	0.0783482619514223	0.154956696781853	0.0763449827720193	0.800825492653152	NA	NA	0.318602610528844	0.833152282693098	84.0259507790496
a9044	loss_cnaOV55	254	AC220	FLT3	7	25	0.0237165266173161	NA	2.44943791037763	2.52800630350489	-0.0785683931272598	0.691004722330928	0.618566177907223	0.123980319196563	0.113701673213215	0.127016956201967	0.800991961360257	NA	NA	0.858836789823272	0.791936185503859	84.0298066934647
a9045	loss_cnaOV41	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.87521959253409	4.80001442963641	0.0752051628976753	0.675982046017063	0.764030424039281	0.0998892012178305	0.111253195762801	0.098432157321799	0.801074334296436	NA	NA	0.766396300070743	0.830328119177759	84.0298066934647
a9046	gain_cnaOV19	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	1.16427984346534	1.37129468080687	-0.207014837341537	1.97897680037817	1.39676818658973	0.13915841827947	0.104607005651596	0.148209874286279	0.801127926885744	NA	NA	0.85806496830154	0.876492034706263	84.0298066934647
a9047	loss_cnaOV39	333	T0901317	LXR	9	23	2.32630161961136	NA	4.88510293997735	4.70179693849125	0.183306001486097	1.09991204421537	1.13479897397849	0.162851593270635	0.166655145245601	0.161531694766559	0.801323365254184	NA	NA	0.0053179826014708	0.680346021575429	84.0352476221115
a9048	gain_cnaOV96	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-3.328205264307	-3.74494014915066	0.416734884843661	1.04540560529761	1.80041884163115	0.239834341336315	0.398634637820812	0.231465520804095	0.801356934507174	NA	NA	0.247681839310635	0.53073402520972	84.0352476221115
a9049	loss_cnaOV84	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.20732916053139	3.25920022455013	-0.0518710640187363	1.39101795830079	0.963215525590858	0.0497563916136549	0.0372900031298659	0.0538519808294384	0.801560125233483	NA	NA	0.568756538959896	0.94728605304214	84.0458210823222
a9050	loss_cnaOV82	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.35233025125503	1.14942824536236	0.202902005892671	2.387478416065	1.42265384726301	0.134935205160255	0.0849859016640203	0.142622189004744	0.801634919511062	NA	NA	0.814001970352583	0.897447223346406	84.0458210823222
a9051	PIK3CA_mut	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.3823974697614	-4.75113267179301	0.368735202031613	2.14700329629458	2.05975427072582	0.177224340221323	0.171744124784529	0.179019025362514	0.801963105009586	NA	NA	0.354227060618647	0.749000039460612	84.0652686683887
a9052	gain_cnaOV26	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.93689223953984	2.78396363353142	0.152928606008412	1.16832378410079	0.95366466648931	0.157829239795165	0.130895739767992	0.160358888592761	0.80199760982819	NA	NA	0.966364394193183	0.844398094463233	84.0652686683887
a9053	loss_cnaOV1	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.23789900702286	4.02972656069932	0.208172446323539	0.532111332397631	1.83728806423387	0.11693122169057	0.39121971972583	0.113304195665335	0.802394047578122	NA	NA	0.624025311245853	0.66097908051518	84.087031760104
a9054	loss_cnaOV40	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	2.53862833684779	2.25288763988387	0.285740696963923	0.912607412906732	1.29899906456079	0.230511294831212	0.313103633526069	0.219969902026478	0.802465618405971	NA	NA	0.39359721405609	0.63003288087227	84.087031760104
a9055	gain_cnaOV48_(SOX17)	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.39760187878098	3.57194317343168	-0.174341294650704	1.2349504036557	0.944261650965601	0.180409339653672	0.141172709555476	0.18463239979345	0.802471099224604	NA	NA	0.72983242052865	0.832223718977745	84.087031760104
a9056	gain_cnaOV26	1129	PF-4708671	RPS6KB1 (p70S6KA)	3	29	2.30258509299405	NA	4.45316892258869	4.17053403718355	0.282634885405145	1.36290933122883	0.944688887457244	0.288948611220558	0.207376146695184	0.299183031744869	0.802629160824149	NA	NA	0.0492423050041735	0.7566203606688	84.0875449981252
a9057	gain_cnaOV94	1009	ATRA	Retinoic acid and retinoid X receptor agonist	7	24	2.30258509299405	NA	4.38825629578786	4.54765894318933	-0.159402647401464	0.580092038524304	0.998049831452052	0.171924764686038	0.274788545291827	0.159714116848806	0.802685747735271	NA	NA	0.530647132052416	0.601033516719851	84.0875449981252
a9058	loss_cnaOV40	330	XMD13-2	RIPK	7	25	2.32630161961136	NA	4.00694733096651	4.10560316015839	-0.0986558291918813	1.19498684948771	1.11156788515966	0.0874031161726118	0.0825580877598569	0.088753759899883	0.802747590565549	NA	NA	0.82056022828477	0.848924495863321	84.0875449981252
a9059	loss_cnaOV85	164	JQ12	HDAC	6	13	1.63315443905142	NA	1.52254311697765	1.9191314915368	-0.39658837455915	2.75710439614145	1.97812024827842	0.177397659357727	0.143842349645582	0.200487495593003	0.80283048690232	NA	NA	0.663397721797463	0.760111010120962	84.0875449981252
a9060	loss_cnaOV38	1017	Olaparib	PARP1, PARP2	8	23	1.6094379124341	NA	4.21339868811476	3.88484977879247	0.328548909322292	1.09742022792466	1.18939912396153	0.281325410871924	0.299382953732877	0.276230999925404	0.803006043288026	NA	NA	0.0844499751976203	0.487983115778311	84.0966493572265
a9061	loss_cnaOV52, loss_cnaOV53	291	KIN001-266	MAP3K8 (COT)	8	24	2.99573227355399	NA	3.39225742218288	3.27250244893718	0.119754973245695	0.767937986434587	1.20068332268089	0.107419288052187	0.155943546694048	0.0997390160948566	0.803369555128716	NA	NA	0.951182890988947	0.74690508548182	84.1254336004103
a9062	loss_cnaOV52, loss_cnaOV53	1032	Afatinib	ERBB2, EGFR	8	23	-0.693147180559945	NA	0.511697521213879	0.303321328405231	0.208376192808647	2.20780459426089	1.48366614899176	0.123507157926608	0.0943816284060257	0.140446820162508	0.803681640998843	NA	NA	0.838083130312486	0.809395942241596	84.1488269767948
a9063	loss_cnaOV55	301	PHA-793887	CDK-pan	7	25	2.32630161961136	NA	2.92238888850489	3.03432567732484	-0.111936788819952	1.03605782033075	1.75351407365932	0.0684461316792325	0.108041063561701	0.0638356945640913	0.803949761352653	NA	NA	0.66510745568917	0.833940139869562	84.1493002516321
a9064	loss_cnaOV102	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	1.98710928117076	1.65221157442069	0.334897706750071	1.58223752571592	1.48637958449557	0.224317695374833	0.211660829241512	0.225311024346263	0.803986325359796	NA	NA	0.328938991240097	0.754317093528666	84.1493002516321
a9065	loss_cnaOV85	283	GSK2126458	PI3K, MTOR	7	25	-2.05572501506252	0.0237165266173161	-2.83292333016657	-2.70397566405644	-0.128947666110129	0.75800246168272	1.95646009694437	0.0723432269936748	0.170115102032615	0.0659086614194287	0.804065207042586	NA	NA	0.697780672675485	0.792393036291925	84.1493002516321
a9066	gain_cnaOV26	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	1.9560056425726	1.8428710891929	0.113134553379703	0.993617230409163	1.75935798125182	0.0670465058608237	0.113861303847473	0.0643044534343174	0.804123078668221	NA	NA	0.350379725400583	0.881976487981624	84.1493002516321
a9067	gain_cnaOV19	294	MPS-1-IN-1	MPS1	3	28	2.99573227355399	NA	4.11370945965749	4.30207852231854	-0.188369062661049	0.509764994280573	0.842632002668686	0.228602120433919	0.369521377055112	0.223548431657554	0.804208981283292	NA	NA	0.319462349539991	0.60927827997885	84.1493002516321
a9068	loss_cnaOV39	326	GSK690693	AKT	9	23	2.32630161961136	NA	4.41349157189894	4.04958141790865	0.363910153990286	0.717557017905458	1.64937182595461	0.249213572495498	0.507151550203685	0.220635607001268	0.804377344119803	NA	NA	0.0952136699541473	0.392032218058536	84.1493002516321
a9069	loss_cnaOV39	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	1.34316445657962	1.7822775225645	-0.439113065984887	3.85040908532233	1.61978222982148	0.187327989981743	0.114043224045667	0.271093890215899	0.804460201982148	NA	NA	0.616710175558623	0.815510417057168	84.1493002516321
a9070	gain_cnaOV49	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	3.97022761836604	3.78348017823052	0.186747440135516	0.195482353245711	1.07332850330964	0.179882836013289	0.955316104164064	0.173989081217608	0.804512620932415	NA	NA	0.718610692784485	0.424483992726955	84.1493002516321
a9071	PIK3CA_mut	1371	PLX4720 (rescreen)	BRAF	7	26	2.30258509299405	NA	4.39259775074231	4.56480521412233	-0.172207463380018	0.875888107652073	1.01978476196534	0.1733233897099	0.196608975365177	0.168866480264068	0.804776400165232	NA	NA	0.327933272562962	0.664913708303341	84.1493002516321
a9072	loss_cnaOV34	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.61582181377108	3.37178670674481	0.244035107026274	0.956538770915427	1.26463254362909	0.198721203288375	0.255123069180696	0.192969181645422	0.804904937349254	NA	NA	0.329257619508168	0.635413548084773	84.1493002516321
a9073	PTEN_mut	1008	Methotrexate	Dihydrofolate reductase (DHFR)	4	27	-1.6094379124341	NA	0.397479715077997	0.590628589810781	-0.193148874732783	0.713197073691322	1.26640321956679	0.158207812045497	0.270821182331968	0.152517675056808	0.804937926399924	NA	NA	0.433405669663002	0.669714541920273	84.1493002516321
a9074	gain_cnaOV49	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	0.754003786709966	0.944472918332679	-0.190469131622714	1.1964314662933	1.2855798276954	0.148871686820958	0.159197694969367	0.14815815208003	0.804951507489847	NA	NA	0.957713258091939	0.814739974092136	84.1493002516321
a9075	SMAD4_mut	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.337375791885937	-0.596248644094475	0.258872852208538	1.59326013561115	1.49251973301729	0.172040358849029	0.1624799657146	0.173446853989126	0.804955060965217	NA	NA	0.91006114241639	0.812845380939925	84.1493002516321
a9076	MLL2_mut	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.53734563916879	4.38351385718264	0.153831781986146	0.475489258145848	0.886987694521049	0.177561501462711	0.323523148737381	0.173431698022836	0.805089123972293	NA	NA	0.870178059839751	0.657182876728005	84.1493002516321
a9077	loss_cnaOV16, loss_cnaOV17	1371	PLX4720 (rescreen)	BRAF	6	27	2.30258509299405	NA	4.69073947066881	4.49217344438385	0.198566026284957	1.56251859786212	0.840438946480476	0.199950804429353	0.12708074422707	0.236264665168715	0.805159814693925	NA	NA	0.327935246004272	0.773633034039122	84.1493002516321
a9078	ARID1A_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	9	24	-2.30258509299405	NA	-0.219256018273747	-0.375058140694068	0.155802122420321	1.11063748188609	1.50892732381199	0.109959708085532	0.140281707543074	0.103253562952734	0.805171256930904	NA	NA	0.889533084408001	0.749723444471122	84.1493002516321
a9079	gain_cnaOV94	301	PHA-793887	CDK-pan	7	25	2.32630161961136	NA	3.19323854003629	2.95848777489605	0.234750765140247	1.53521284373997	1.65657595769344	0.143752090612976	0.15291089186589	0.141708422152345	0.805193848680673	NA	NA	0.66511183028774	0.732438903329239	84.1493002516321
a9080	gain_cnaOV96	308	XL-880	MET	5	27	1.63315443905142	NA	0.0946865123431509	0.282433935590887	-0.187747423247737	0.398103455453877	1.03737619082817	0.192241269206606	0.471604605977826	0.180982969252313	0.805467203529919	NA	NA	0.370782580260221	0.492605774395363	84.1565826898274
a9081	loss_cnaOV1	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	4.14619320469642	3.85698114186433	0.289212062832087	1.92518908129175	1.5751101716083	0.180564344140242	0.150225276905287	0.183613862728586	0.805564762631765	NA	NA	0.717081405475432	0.822290783406279	84.1565826898274
a9082	KRAS_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	7	25	2.99573227355399	NA	5.71713757589606	5.71449545159749	0.00264212429856414	0.302446189403781	0.517136504253704	0.0054825902522483	0.00873584918947936	0.00510914289908246	0.805622793149959	NA	NA	0.384202296174796	0.986525313504724	84.1565826898274
a9083	loss_cnaOV57_(ZNRF3)	273	CUDC-101	HDAC, EGFR	4	27	1.63315443905142	NA	0.222372987110204	0.102622337680576	0.119750649429628	2.45565155843109	1.51364057290019	0.0731778504212241	0.0487653262607568	0.0791143231580942	0.805726086225698	NA	NA	0.464299810498867	0.929799973996589	84.1565826898274
a9084	gain_cnaOV51_(MYC)	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.39154108150499	-1.63681759061479	0.2452765091098	0.879807147985222	1.43457862966676	0.185099389835381	0.278784401412842	0.170974601208702	0.805798814218547	NA	NA	0.62530316087467	0.663276968750489	84.1565826898274
a9085	SMARCA4_mut	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.60039567322189	5.79184012949709	-0.191444456275208	0.888713926666151	0.534805508624788	0.338027248849029	0.215417414457965	0.357970239999009	0.805897223325899	NA	NA	0.112535198097923	0.74710976199069	84.1565826898274
a9086	gain_cnaOV50	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	3.70565321438782	3.81460697022257	-0.10895375583475	0.552697048947586	1.0796128568551	0.104862409588693	0.197131061296987	0.100919283373608	0.805941748835336	NA	NA	0.718614986524824	0.760443375599237	84.1565826898274
a9087	gain_cnaOV19	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.25657603193913	3.27822002555621	-0.0216439936170749	0.599044513881389	1.07483271852775	0.0206164007458114	0.0361308602541688	0.0201370810954859	0.806069074909003	NA	NA	0.0935712080482595	0.959702920507676	84.1565826898274
a9088	loss_cnaOV35	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	3.07444546092833	2.88028200838147	0.194163452546857	1.09437843400129	0.792663434255228	0.226205763083349	0.177418931618519	0.244950686705121	0.806069412095538	NA	NA	0.333555719993395	0.725465400728892	84.1565826898274
a9089	loss_cnaOV38	219	AT-7519	CDK9	8	24	2.32630161961136	NA	1.4871726829723	1.5012193804239	-0.0140466974516047	1.72570315703155	1.71662244714973	0.0081726450331982	0.00813969505379301	0.00818275298387699	0.806309804130014	NA	NA	0.318632034123134	0.984400433577945	84.1565826898274
a9090	loss_cnaOV34	206	Ruxolitinib	JAK1, JAK2, TYK2	5	27	1.65632149833295	0.0237165266173161	4.5426560628713	4.43513372280272	0.107522340068587	0.849360373852974	0.50033643169793	0.192143083879339	0.126592131418647	0.214900081738405	0.806400783341586	NA	NA	0.367354012318501	0.795857860212877	84.1565826898274
a9091	TP53_mut	133	Doxorubicin	DNA intercalating	12	7	0.0237165266173161	NA	-1.62019682339556	-1.49011282791219	-0.130083995483362	1.59645109171371	0.571848362773226	0.0979281134217517	0.0814832325014876	0.22747987744952	0.80644332384793	NA	NA	0.625307682570612	0.801755872759202	84.1565826898274
a9092	gain_cnaOV95_(MECOM)	298	OSI-930	KIT, VEGFR, PDGFR	9	23	2.32630161961136	NA	4.53209276422402	4.42005569800403	0.112037066219983	0.586782980696101	1.10178044395161	0.11305776653959	0.190934416821486	0.10168728881968	0.806477315798397	NA	NA	0.0321322767301916	0.713317873303721	84.1565826898274
a9093	loss_cnaOV58	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.24129033025814	2.37832883848623	-0.137038508228086	1.09117607996038	0.834758240471783	0.156918842061317	0.125587896165266	0.164165505153487	0.806621982966492	NA	NA	0.652279439194724	0.800518536357411	84.1565826898274
a9094	loss_cnaOV52, loss_cnaOV53	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	1.6094379124341	NA	1.37975653364013	1.32603383196427	0.0537227016758599	2.07535731755207	1.03887593973217	0.0394083689963322	0.0258860010377524	0.0517123360174361	0.806677691115538	NA	NA	0.582906110660029	0.945689905345907	84.1565826898274
a9095	loss_cnaOV36	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	0.923527647683335	0.741168197541524	0.182359450141811	1.0051754232594	1.05862959103872	0.172827948652952	0.181420522151735	0.172259921397891	0.806682654532491	NA	NA	0.773098597072853	0.789106655994963	84.1565826898274
a9096	gain_cnaOV96	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	5.14100371880892	5.0026188357208	0.138384883088117	1.38338313554954	1.15717863944895	0.115301613934258	0.100033663510828	0.11958817625083	0.807098516397759	NA	NA	0.802639945317302	0.862819332210288	84.188411799773
a9097	gain_cnaOV72_(ASXL1)	163	JQ1	BRD4	4	15	0.940007258491471	NA	0.410349334862012	0.00268758042243067	0.407661754439581	2.02427383137144	1.84928500358125	0.216685938197284	0.201386664255494	0.220442902878746	0.807165209813863	NA	NA	0.585530944881944	0.732360631350811	84.188411799773
a9098	loss_cnaOV70	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.23150325166192	4.03038819056425	0.201115061097668	0.535948893467828	1.83728471705781	0.112962397926893	0.375250445609402	0.109463198180699	0.807387598692071	NA	NA	0.624044622690828	0.67279379241415	84.2023512003708
a9099	ARID1A_mut	253	XMD14-99	EPHB3, CAMK1	8	24	2.32630161961136	NA	4.58344297245963	4.95227085435232	-0.368827881892688	0.685472081525384	0.576064183668793	0.611280010626594	0.538064046418833	0.64025484025708	0.807666891506457	NA	NA	0.0507954559663337	0.199488039045121	84.2175284009556
a9100	gain_cnaOV95_(MECOM)	1004	Vinblastine	Microtubules	8	23	-2.30258509299405	NA	-3.13279000719118	-3.37863083946351	0.24584083227233	1.86970015603037	1.82369081182832	0.133980350336445	0.131486768870087	0.134804008814337	0.80771064651034	NA	NA	0.14155553515845	0.752729559486451	84.2175284009556
a9101	PTEN_mut	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.19010363310878	1.52952881705606	-0.33942518394728	1.97657607706809	1.69554923967878	0.197832846070354	0.171723814673888	0.200185978681211	0.808027448997831	NA	NA	0.318641066590959	0.797991919997123	84.2340765734982
a9102	loss_cnaOV36	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.71800387430268	4.80304312858717	-0.0850392542844887	0.948700283559686	0.644638357348168	0.12707199000046	0.0896376397879917	0.131917769575972	0.808055631479076	NA	NA	0.763314073180262	0.892250477782232	84.2340765734982
a9103	ARID1A_mut	1129	PF-4708671	RPS6KB1 (p70S6KA)	8	24	2.30258509299405	NA	3.76068808931192	4.3424787138164	-0.581790624504484	0.70416411645121	1.00906006862428	0.614519020440476	0.826214529982792	0.576566888924341	0.808431529208816	NA	NA	0.0492560488986193	0.0891506528377946	84.2340765734982
a9104	SMAD4_mut	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	5.02034584020354	4.84348299184559	0.176862848357957	0.731347128849749	0.614790195052066	0.283780047856497	0.24183160277955	0.287680008206667	0.808456559634254	NA	NA	0.0507973374825059	0.720482953740941	84.2340765734982
a9105	SMAD4_mut	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	0.253078140223469	0.103609308755213	0.149468831468256	1.45120663238298	1.64920741326526	0.0913444126331758	0.102996243355654	0.0906307055534776	0.808462170260959	NA	NA	0.464313686420408	0.879400127655128	84.2340765734982
a9106	loss_cnaOV38	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	2.10042904786413	2.02239424728931	0.0780348005748217	2.89144468234225	1.64101938985398	0.0389426868880543	0.0269881699800006	0.0475526377429125	0.808720953854001	NA	NA	0.134427371948924	0.943840559561403	84.2340765734982
a9107	loss_cnaOV42	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.0967399820854	1.36595037350153	-0.269210391416138	0.302565037047023	1.40806150351365	0.197808922028548	0.889760410005004	0.191192210527988	0.808823213816082	NA	NA	0.582915294123512	0.410353084951113	84.2340765734982
a9108	loss_cnaOV38	1170	CCT018159	HSP90	8	25	2.30258509299405	NA	3.90124836703504	3.62894656805638	0.272301798978661	1.62523851372261	1.08556498062892	0.221684559962962	0.167545745857913	0.250838783341098	0.808890970158083	NA	NA	0.200412668259657	0.667913398930148	84.2340765734982
a9109	loss_cnaOV57_(ZNRF3)	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	2.72142057143005	2.51161342809303	0.20980714333702	0.955139657611594	1.05010344183062	0.201487334354338	0.219661220916803	0.199796643815649	0.808910484436829	NA	NA	0.397529197735117	0.704684996589751	84.2340765734982
a9110	gain_cnaOV19	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.26810080650125	4.43027321493275	-0.1621724084315	0.468879125096867	0.982644014570508	0.169456917684667	0.34587252822995	0.165036784457881	0.80915457641236	NA	NA	0.787559621637876	0.644422085895523	84.2340765734982
a9111	loss_cnaOV38	1003	Camptothecin	TOP1	8	23	-2.30258509299405	NA	-3.40623250387013	-3.79027587188412	0.384043368013993	2.23076625383172	1.54409750912014	0.221362159346694	0.172157601610807	0.248717043933858	0.809188424846743	NA	NA	0.247723701243455	0.66229385822035	84.2340765734982
a9112	SMARCA4_mut	1378	Bleomycin (50 uM)	DNA damage	3	29	3.91202300542815	NA	1.44940962019317	2.10319536059576	-0.653785740402587	0.664352815953534	2.05680585682767	0.327801952810741	0.984094181138105	0.317864585144152	0.809240688356443	NA	NA	0.134429503244461	0.264239562479812	84.2340765734982
a9113	loss_cnaOV58	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.29990188554384	4.41492654304523	-0.115024657501388	1.1944565539085	0.806670129018261	0.132744099904457	0.0962987369653619	0.142591938592514	0.809266155938043	NA	NA	0.870183797872205	0.844676859918491	84.2340765734982
a9114	loss_cnaOV59	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	2.67181363343706	2.76004806825288	-0.0882344348158242	0.975179712356422	1.75531697998646	0.0521001936297179	0.0904801788817106	0.0502669522495617	0.809377460931421	NA	NA	0.323840427034085	0.885763187328756	84.2340765734982
a9115	loss_cnaOV21, loss_cnaOV22	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.86207836135562	4.85985548965744	0.00222287169817204	0.285783412054305	0.64294242174097	0.00355370090732089	0.00777816907634107	0.00345734178210377	0.809447977260901	NA	NA	0.0507996879327529	0.991753474029693	84.2340765734982
a9116	gain_cnaOV4_(KRAS)	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	-0.00603339920507422	0.154272035843829	-0.160305435048903	2.09713922665119	1.49174849687043	0.0980166543987646	0.0764400536748751	0.10746143561412	0.809763594435068	NA	NA	0.464320211887529	0.855042653704595	84.2340765734982
a9117	SMAD4_mut	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	2.71540265125291	2.85747145848076	-0.142068807227851	1.73196729994121	1.87712022936196	0.0760623393255049	0.0820274188968078	0.0756844473814766	0.809815400121021	NA	NA	0.34885672768955	0.90327884055719	84.2340765734982
a9118	loss_cnaOV43_(NF1)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	1.13193062126963	0.980519808804448	0.15141081246518	1.15957546307593	1.61393815982013	0.0969950164955884	0.130574350084593	0.0938145067974936	0.809956724719054	NA	NA	0.792089959839216	0.809174325116381	84.2340765734982
a9119	loss_cnaOV56	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.45418048555873	4.31598053239663	0.138199953162106	0.460586907639729	0.599391285028355	0.233893761817192	0.300051848782045	0.230567171418864	0.810009169193539	NA	NA	0.256589686261698	0.667557327016073	84.2340765734982
a9120	loss_cnaOV42	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	0.496112747076823	0.909938542014399	-0.413825794937577	1.49029940419524	2.15004792259566	0.198064458479302	0.277679635228092	0.192472823786171	0.810113915483004	NA	NA	0.418599739080746	0.648648881378332	84.2340765734982
a9121	loss_cnaOV1	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-0.15703235690364	-0.350120082347015	0.193087725443374	0.466927690425039	1.46048062651211	0.136212000225974	0.413528110246811	0.132208344252058	0.810205858483454	NA	NA	0.889538967806192	0.625534084288183	84.2340765734982
a9122	PIK3CA_mut	134	Etoposide	TOP2	5	14	2.77258872223978	NA	2.77180025717163	2.10885027063043	0.662949986541201	0.862986778368667	2.03435326194806	0.362747869196703	0.768204105970659	0.325877515445067	0.810244396015731	NA	NA	0.413513482202778	0.334782034520237	84.2340765734982
a9123	loss_cnaOV84	203	BMS-345541	IKBKB	6	26	2.77258872223978	NA	3.30480066779974	3.26958864731342	0.0352120204863207	1.07058561184188	1.04555440839552	0.0335426777302078	0.0328904294031568	0.0336778461298404	0.810284227277963	NA	NA	0.0935856845297784	0.943796182086757	84.2340765734982
a9124	gain_cnaOV50	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	2.71040075566587	2.7168408822162	-0.00644012655033288	0.543974612814133	0.577380440490532	0.0112172443080468	0.0118390204223251	0.0111540435018226	0.810421639875076	NA	NA	0.137615151707042	0.983512074987703	84.2340765734982
a9125	loss_cnaOV85	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	3.80066588276913	4.09765662372142	-0.296990740952288	1.19393317042859	1.57273091675414	0.197385880194163	0.248749886767678	0.188837605841201	0.810460044556352	NA	NA	0.332276733880658	0.598738143274496	84.2340765734982
a9126	PIK3CA_mut	261	TL-1-85	MAP3K7 (TAK1)	6	26	2.32630161961136	NA	3.55090847107833	3.5566810322843	-0.00577256120596692	0.963159048868064	0.968709321056362	0.00596470532337051	0.00599336237639155	0.00595902308410952	0.810517268958714	NA	NA	0.729855553340623	0.989797035638817	84.2340765734982
a9127	loss_cnaOV34	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	3.15299240231285	3.41623230657599	-0.26323990426314	0.669667454806373	1.78503774040058	0.156720803925415	0.393090484499135	0.147470217746806	0.810534128962442	NA	NA	0.631581366531848	0.571131013056638	84.2340765734982
a9128	loss_cnaOV38	253	XMD14-99	EPHB3, CAMK1	8	24	2.32630161961136	NA	4.98397415064735	4.81876046162308	0.165213689024278	0.77099807316592	0.567719196734377	0.265988803698594	0.214285475897323	0.291013039500191	0.810562798030758	NA	NA	0.0508023153156115	0.589683060465125	84.2340765734982
a9129	gain_cnaOV95_(MECOM)	203	BMS-345541	IKBKB	9	23	2.77258872223978	NA	3.21992676468146	3.29820730238323	-0.0782805377017626	0.975142012063994	1.0749113641934	0.0746073054530588	0.0802760384983037	0.0728251094084425	0.810724774061584	NA	NA	0.0935871778000577	0.845322128130403	84.2340765734982
a9130	loss_cnaOV40	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	8	25	-2.30258509299405	NA	-0.243515005077184	-0.361063180020156	0.117548174942972	1.8141228742106	1.27922167341475	0.0829113668067851	0.0647961483833458	0.091890387245542	0.810885797592259	NA	NA	0.889539749616721	0.86846286412769	84.2340765734982
a9131	gain_cnaOV49	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.64211337408421	2.88669704821376	-0.24458367412955	0.389782814578977	0.828361851799464	0.303236596358802	0.627487064543202	0.295261875710761	0.810953313684558	NA	NA	0.0200851400541987	0.41761972748375	84.2340765734982
a9132	KRAS_mut	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	0.051698316181591	-0.0955861345268395	0.14728445070843	0.922072060849578	0.982025231273594	0.151787846564682	0.159732039351377	0.149980312132527	0.811009842132793	NA	NA	0.551058394954985	0.720300317772494	84.2340765734982
a9133	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.46892888465996	4.52939407926678	-0.0604651946068184	0.473399526954262	0.631909556304948	0.100183049119405	0.127725507027514	0.095686469690987	0.811027763781725	NA	NA	0.616928783678799	0.786976372185121	84.2340765734982
a9134	loss_cnaOV38	328	SNX-2112	HSP90	8	24	0.940007258491471	NA	0.536394374043841	0.749400631964026	-0.213006257920185	2.756444787971	2.1806584823541	0.0915060780003573	0.0772757208305912	0.0976797878456589	0.811163374248036	NA	NA	0.946127061410708	0.846357923097709	84.2340765734982
a9135	loss_cnaOV85	1013	Nilotinib	ABL	5	16	0.693147180559945	NA	3.41960805929181	3.19610501018867	0.223503049103134	1.29480109458216	0.95783480577609	0.215340232345636	0.17261574000697	0.233341958086436	0.811202426723787	NA	NA	0.568823310215853	0.73474361698501	84.2340765734982
a9136	gain_cnaOV19	170	Shikonin	unknown	3	15	2.77258872223978	NA	0.0545813768404816	-0.0244535165168869	0.0790348933573685	0.489646251592276	0.837530425443448	0.0985058884643264	0.161412229952452	0.0943665936858614	0.811223221992704	NA	NA	0.58804917786673	0.833423639456544	84.2340765734982
a9137	loss_cnaOV57_(ZNRF3)	304	SB52334	ALK5	4	28	2.99573227355399	NA	4.4188149897575	4.3591869744554	0.0596280153020974	0.876107217555196	1.09051261262076	0.0556748084247484	0.0680601804291616	0.054678886435616	0.81126788527807	NA	NA	0.35435203408576	0.907337519082838	84.2340765734982
a9138	loss_cnaOV41	1495	AZD-2281	PARP1, PARP2	5	28	2.30258509299405	NA	3.74939758164859	3.52763613100383	0.221761450644762	1.62589608084424	0.763005430524238	0.240794927370634	0.136393373019026	0.29064203447726	0.811315594175888	NA	NA	0.144901274757053	0.778665389378926	84.2340765734982
a9139	KRAS_mut	228	KIN001-102	AKT1	7	25	2.32630161961136	NA	2.70513384001153	2.81230361524271	-0.107169775231184	0.938717771783046	1.30217076762657	0.0865636659907059	0.1141661300687	0.0823008609128268	0.811331653409214	NA	NA	0.0964711657145606	0.811349915374112	84.2340765734982
a9140	gain_cnaOV95_(MECOM)	1039	SL 0101-1	RSK, AURKB, PIM3	8	25	2.30258509299405	NA	4.99896568208047	4.91804620645387	0.0809194756265939	0.94416892990873	0.786515907066372	0.0981135491877118	0.0857044465913701	0.10288345715526	0.811433012751288	NA	NA	0.946255169350658	0.830712778162552	84.2353827698489
a9141	MLL2_mut	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	0.802462495308491	0.939088617377288	-0.136626122068797	0.227715475161885	1.32690128466485	0.106732351467344	0.599986109734827	0.102966304764191	0.811635005934527	NA	NA	0.957716594085066	0.639041298545618	84.2419783125842
a9142	loss_cnaOV1	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.45587258401622	3.28656897930713	0.169303604709089	0.737463324610264	1.13713683616767	0.151847499003907	0.22957562641988	0.14888586784302	0.811674117471454	NA	NA	0.951187358451379	0.744596588339692	84.2419783125842
a9143	loss_cnaOV35	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	5.88332560945536	5.95863258740611	-0.0753069779507527	0.94617858018397	0.665178963694041	0.106405737222485	0.07959066029175	0.113213108142415	0.811890447716442	NA	NA	0.909166711019001	0.871590450774788	84.2552145032821
a9144	loss_cnaOV87, loss_cnaOV88	302	PI-103	PI3Ka, PRKDC (DNAPK)	3	29	2.32630161961136	NA	1.12647090622499	1.30679858801197	-0.180327681786982	1.43830359155956	2.39755038239691	0.0768713985005372	0.125375256548898	0.0752133023401586	0.812073832126664	NA	NA	0.36600570011036	0.859417946853565	84.2615288734416
a9145	gain_cnaOV4_(KRAS)	164	JQ12	HDAC	6	13	1.63315443905142	NA	1.65506840044231	1.85796597609157	-0.202897575649266	2.2278023635208	2.2476803834595	0.0905044388499314	0.0910752133903876	0.0902697630598964	0.812128905097227	NA	NA	0.663456943478113	0.857721785343937	84.2615288734416
a9146	loss_cnaOV16, loss_cnaOV17	1006	Cytarabine	DNA synthesis	6	25	0.693147180559945	NA	0.0295693141921585	-0.145120166969983	0.174689481162142	1.35973453247314	1.24849094773304	0.137727850572618	0.128473225464392	0.139920502811283	0.81230270980016	NA	NA	0.768384284929465	0.78223620017019	84.2703468771245
a9147	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	279	BIX02189	MAP2K5 (MEK5)	7	25	2.99573227355399	NA	4.49579220122527	4.41309245101992	0.0826997502053484	0.935999780829462	0.686436118140287	0.111292506819141	0.088354454668848	0.120476979605037	0.812450748901458	NA	NA	0.52655814766424	0.83300860349404	84.2732830872675
a9148	gain_cnaOV48_(SOX17)	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.49705187142809	4.42436900240657	0.07268286902152	0.840897418371769	0.736159561386141	0.0977444219789147	0.0864348818697243	0.0987324933804606	0.812508649002245	NA	NA	0.526558402708276	0.896944351028045	84.2732830872675
a9149	gain_cnaOV72_(ASXL1)	185	OSI-906	IGF1R	4	14	0.940007258491471	NA	2.40621938946203	2.15149083682301	0.254728552639025	0.977906239155423	1.38755498314703	0.19290866391961	0.260483615340284	0.183580871196391	0.812714485630507	NA	NA	0.688959782991503	0.69065225809942	84.2854188983954
a9150	gain_cnaOV94	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	1.519977123858	1.92462643645188	-0.404649312593882	1.19606190708076	1.73516960894277	0.240756002712641	0.338318033705725	0.233204472063358	0.812875663466515	NA	NA	0.350462447096355	0.647000973808395	84.2929210656794
a9151	loss_cnaOV44	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.21460585327462	2.37163837002052	-0.157032516745898	1.54003386876743	0.805090736773549	0.179765546591431	0.101966924189518	0.195049464083036	0.81297965265643	NA	NA	0.652301855284255	0.876993874900746	84.2944919395487
a9152	loss_cnaOV59	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.31170744952236	4.33196913206268	-0.0202616825403199	0.498806232876617	0.602190480822863	0.0342065778960724	0.0406203475515346	0.0336466337239893	0.813244711806802	NA	NA	0.256606485120562	0.944490433567978	84.3078675451377
a9153	loss_cnaOV20	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-3.86562222959934	-4.01361615697223	0.147993927372888	2.44171348227775	1.68542492398137	0.080361773281261	0.0606106852614139	0.0878080804829271	0.813286363156417	NA	NA	0.593988187112641	0.914871682327379	84.3078675451377
a9154	PIK3R1_mut	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	3.28137155820408	3.58902039550893	-0.307648837304849	1.99180582737416	1.67177231184028	0.178921786294543	0.154457243309921	0.184025560852955	0.813574556085932	NA	NA	0.700119183251561	0.758618244150403	84.3169655284737
a9155	loss_cnaOV39	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	3.76614315171431	4.02018200807	-0.254038856355691	2.77975046969438	0.916590247487937	0.161950206099875	0.0913890865835958	0.277156403367726	0.813630817774667	NA	NA	0.74548000930968	0.850192557809635	84.3169655284737
a9156	loss_cnaOV57_(ZNRF3)	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	2.83345095936524	3.03748612964243	-0.204035170277192	1.77140912731013	0.983896169104265	0.18743010488464	0.115182408813156	0.207374697335131	0.813640720622342	NA	NA	0.436970284700615	0.834996401644331	84.3169655284737
a9157	loss_cnaOV20	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.61003277462903	3.37285875103037	0.237174023598656	1.65467536492753	1.14863923423259	0.193104403405418	0.143335683014199	0.206482607010297	0.813827577773617	NA	NA	0.329303971172716	0.771798843197249	84.3271193528864
a9158	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	272	AR-42	HDAC	5	25	1.63315443905142	NA	0.0217190477518053	0.349773520358785	-0.32805447260698	1.51269665390088	1.90647259774114	0.176816099175593	0.216867322183206	0.172074056031894	0.81391823948801	NA	NA	0.488550117051097	0.685677156186826	84.3273044773166
a9159	gain_cnaOV50	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.24065130790431	3.98107315073227	0.259578157172041	1.67341686224938	0.962157250149786	0.246025829167124	0.155118645585488	0.269787664263436	0.814415716591412	NA	NA	0.10648053591021	0.779944455457781	84.3477422168287
a9160	loss_cnaOV1	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.76465878582205	5.77424051028993	-0.00958172446788463	0.362224345684664	0.581783103840083	0.0168287666079178	0.0264524584888782	0.0164695818847953	0.814534065915099	NA	NA	0.112568620860996	0.9700227560911	84.3477422168287
a9161	loss_cnaOV52, loss_cnaOV53	1004	Vinblastine	Microtubules	8	23	-2.30258509299405	NA	-2.97596293531369	-3.43317938620351	0.457216450889812	1.42068291010039	1.93800112315208	0.250310779548479	0.321828641450684	0.235921664558258	0.814624788391462	NA	NA	0.141585196122543	0.48792940833011	84.3477422168287
a9162	PIK3R1_mut	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	3.82852139863336	3.62026289703384	0.208258501599524	1.29644113348008	2.10939654807633	0.101951939432057	0.160638609977214	0.0987289477597021	0.814661554338853	NA	NA	0.74871335297081	0.794135107059301	84.3477422168287
a9163	SMAD4_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	2.04597452773718	2.32038169222395	-0.274407164486768	1.0211416578374	1.44579773213862	0.193163898061535	0.268725854420546	0.189796372194378	0.814670884849021	NA	NA	0.532197676022212	0.701770078015928	84.3477422168287
a9164	loss_cnaOV39	206	Ruxolitinib	JAK1, JAK2, TYK2	9	23	1.65632149833295	0.0237165266173161	4.52281120653398	4.42419956396626	0.0986116425677128	0.767147389967953	0.460836729903025	0.176352292593995	0.128543281066018	0.21398390399234	0.814740175001073	NA	NA	0.367396736945437	0.725374805231891	84.3477422168287
a9165	gain_cnaOV18_(CCNE1)	1072	BMS-708163	g-secretase	4	29	1.6094379124341	NA	3.93197350775876	3.82887994889351	0.103093558865249	0.479009047644443	0.902963653267091	0.118362063249875	0.215222571206573	0.114172434839694	0.814753511996444	NA	NA	0.924139028048816	0.735538861760704	84.3477422168287
a9166	loss_cnaOV43_(NF1)	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.202080593249881	-0.0376800808759423	-0.164400512373939	1.21865763768482	0.926332107257778	0.169413428953598	0.134902951649541	0.177474699501256	0.814877180086239	NA	NA	0.551074771455014	0.786081494570271	84.3477422168287
a9167	loss_cnaOV102	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.56062867972059	4.36928346251891	0.191345217201677	1.00750701410828	0.990767864167846	0.192909210084802	0.189919488918925	0.193128203004838	0.814915572223959	NA	NA	0.513732489881914	0.778837203250344	84.3477422168287
a9168	gain_cnaOV19	308	XL-880	MET	3	29	1.63315443905142	NA	0.0672940086252854	0.27231954471703	-0.205025536091744	0.261320168409435	1.00909569774564	0.20980678034485	0.784576013935943	0.203177495008431	0.81523175514529	NA	NA	0.370832610316401	0.412171808322197	84.3646607274385
a9169	PIK3CA_mut	279	BIX02189	MAP2K5 (MEK5)	6	26	2.99573227355399	NA	4.58217223735534	4.39633935615165	0.185832881203689	0.83955280057797	0.718611095138696	0.251077436487039	0.221347461500643	0.258600072362955	0.815495656704532	NA	NA	0.526571445211661	0.631887126323844	84.3646607274385
a9170	gain_cnaOV49	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.177571710190479	0.149750364156707	-0.327322074347186	1.08916179259163	1.66718408218106	0.20033192971083	0.300526585282003	0.196332293383568	0.815676069416636	NA	NA	0.464349254154318	0.672267508404139	84.3646607274385
a9171	ARID1A_mut	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	-0.0348982039779847	0.173569068510042	-0.208467272488026	1.30197445488157	1.35797178094718	0.154993598001588	0.160116253975957	0.153513699925797	0.815726841334524	NA	NA	0.871138977956777	0.76965050738501	84.3646607274385
a9172	loss_cnaOV57_(ZNRF3)	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	2.79597678739245	2.78784357541352	0.00813321197892325	1.65450724735869	1.18373407414096	0.00656492988530061	0.0049157910863838	0.00687081005488969	0.81575821141121	NA	NA	0.0964861558563999	0.992950026485556	84.3646607274385
a9173	loss_cnaOV35	1264	SGC0946	Q8TEK3 (DOT1L)	5	28	-0.693147180559945	NA	2.14735679319578	2.10958989770183	0.0377668954939443	0.807141007049933	0.517680092635714	0.067028095450867	0.0467909512267017	0.0729541197956021	0.815887152600439	NA	NA	0.0433359711809136	0.923809829918473	84.3646607274385
a9174	MLL2_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	2.70875656509371	2.83083688958638	-0.12208032449267	0.719221069472434	1.61480964803531	0.0776346428283837	0.169739638720845	0.0756004428393167	0.816177370698459	NA	NA	0.968973651008603	0.821198183296507	84.3646607274385
a9175	TP53_mut	175	PAC-1	CASP3 agonist	11	7	0.940007258491471	NA	2.07968649258323	2.23409310708541	-0.154406614502172	1.46718477129044	1.21212133160699	0.112125824336097	0.105240060777325	0.127385444407174	0.816259952558309	NA	NA	0.893363787724713	0.811774936998022	84.3646607274385
a9176	KRAS_mut	1203	QL-XII-61	BTK	6	17	2.30258509299405	NA	3.43868651069074	4.05139192619439	-0.612705415503656	1.40813713171656	1.52098820350576	0.409866056171314	0.435117718085276	0.402833772209027	0.816261103997499	NA	NA	0.071680050414528	0.391958169894976	84.3646607274385
a9177	loss_cnaOV16, loss_cnaOV17	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	6	26	0.246860077931526	2.32630161961136	0.841606069119902	1.04169428959034	-0.200088220470436	1.40875758587429	1.58848004180002	0.128264569183521	0.142031689821397	0.125962061344946	0.816426582992217	NA	NA	0.792103984969016	0.767275212127803	84.3646607274385
a9178	loss_cnaOV39	1054	PD-0332991	CDK4, CDK6	10	23	1.38629436111989	0.693147180559945	2.59982189525961	2.14691109693254	0.452910798327071	1.93938542303826	1.72864056050993	0.252686951550385	0.233533155888909	0.262004032922534	0.816517720594985	NA	NA	0.112334280486146	0.533606515971875	84.3646607274385
a9179	loss_cnaOV44	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.40744801493477	3.57092460762267	-0.163476592687902	1.38568332929948	0.929392829007263	0.169136367173632	0.117975434380484	0.175896120118035	0.816610854031979	NA	NA	0.729872381941408	0.858711260664784	84.3646607274385
a9180	loss_cnaOV16, loss_cnaOV17	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	6	27	-2.30258509299405	NA	-0.225481969113066	-0.356363249127517	0.130881280014451	1.61391950184142	1.37682824702743	0.0923159908368624	0.0810952961812041	0.0950599904505331	0.816638910153968	NA	NA	0.88954624370355	0.859222287190338	84.3646607274385
a9181	gain_cnaOV19	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	1.78272863418221	1.95554581713397	-0.17281718295176	0.356285109508435	1.39620655092454	0.127823646090581	0.485053060988697	0.123776229840294	0.816685897038648	NA	NA	0.839903861314937	0.611585612652229	84.3646607274385
a9182	loss_cnaOV58	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.09064386545186	3.95932705687215	0.131316808579706	1.21211148600492	0.671868100690957	0.171379530436599	0.108337236381219	0.195450280262835	0.816765246969964	NA	NA	0.527795803664595	0.824131345822577	84.3646607274385
a9183	PIK3CA_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	NA	1.57843971341887	1.11849543456142	0.459944278857448	0.765404969493462	1.32153151061107	0.372841767501051	0.600916243282082	0.348038828559428	0.816779786412472	NA	NA	0.269395209156579	0.252747859485157	84.3646607274385
a9184	gain_cnaOV51_(MYC)	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	4.89787107879128	5.07956728693509	-0.181696208143811	1.62409273373747	1.03315266803011	0.151577784975813	0.111875513244666	0.175865788054584	0.816784193759507	NA	NA	0.8026768985414	0.824032262965161	84.3646607274385
a9185	loss_cnaOV85	308	XL-880	MET	7	25	1.63315443905142	NA	0.26858455823687	0.248762276600465	0.0198222816364055	0.435979405210856	1.07276742801282	0.0202449591907249	0.0454660963327356	0.0184777064616178	0.816804457112491	NA	NA	0.370840409199578	0.942164727923163	84.3646607274385
a9186	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	4.04352204642463	3.9620158215134	0.0815062249112279	1.01062821130038	0.69286946530582	0.106262710437533	0.0806490695587784	0.117635758238029	0.816949710295111	NA	NA	0.527796594452256	0.846251827444948	84.3646607274385
a9187	loss_cnaOV34	1170	CCT018159	HSP90	5	28	2.30258509299405	NA	3.92775478067326	3.65338847265441	0.274366308018851	1.54481507517552	1.17625970302686	0.223055474756614	0.177604628817904	0.233253173013431	0.816956622447375	NA	NA	0.200449179910861	0.721331295244057	84.3646607274385
a9188	gain_cnaOV95_(MECOM)	228	KIN001-102	AKT1	9	23	2.32630161961136	NA	2.88325096025048	2.75192472256061	0.131326237689871	0.911714343676636	1.33628007603919	0.106131713540935	0.144043184798735	0.0982774794331512	0.817072419984672	NA	NA	0.0964905329653902	0.75315694537869	84.3646607274385
a9189	gain_cnaOV50	223	ZSTK474	PI3K	4	28	1.63315443905142	2.32630161961136	0.663299325428942	0.77183083464423	-0.108531509215288	0.921468098478184	1.06982406202464	0.102783170065461	0.117781081509527	0.101447997916491	0.817122206910614	NA	NA	0.773123358808317	0.839178411897612	84.3646607274385
a9190	loss_cnaOV70	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.11953530322641	3.87932019537441	0.240215107852003	0.419131087134457	1.11231128804605	0.222197834179588	0.573126439974476	0.215960325525401	0.817124061395953	NA	NA	0.318899496741573	0.477709122901671	84.3646607274385
a9191	gain_cnaOV51_(MYC)	1036	PLX4720	BRAF	8	25	2.30258509299405	NA	4.30364447353508	4.30924934819601	-0.00560487466092496	1.21780745795934	1.34912324887443	0.00424414580183211	0.00460243088863732	0.00415445710064007	0.817252680058125	NA	NA	0.373555381820899	0.991366612411156	84.3687595732074
a9192	PTEN_mut	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	1.34701647572405	1.61400768642533	-0.266991210701282	0.821287859956144	1.09547499266485	0.251342284045525	0.325088466199341	0.243721867216521	0.817370530724	NA	NA	0.290511714515018	0.598923965457671	84.3717460182115
a9193	loss_cnaOV39	1006	Cytarabine	DNA synthesis	10	21	0.693147180559945	NA	-0.155634532172118	-0.0902020460654976	-0.0654324861066206	1.3556656820505	1.22947333253808	0.0515224916152741	0.0482659456331826	0.0532199311485221	0.817483108764419	NA	NA	0.768397044649561	0.898638070672226	84.3741876144952
a9194	gain_cnaOV51_(MYC)	1377	Afatinib (rescreen)	ERBB2, EGFR	8	25	2.30258509299405	NA	2.47426720249969	2.71297958172777	-0.238712379228089	2.13770291911452	1.56851549998786	0.13930076600374	0.111667705130406	0.152190003369388	0.817604092405736	NA	NA	0.641777664279039	0.77675160350612	84.3774961454132
a9195	loss_cnaOV54	312	AV-951	VEGFR	10	22	-2.05572501506252	NA	0.771464405229408	0.580021086896508	0.1914433183329	0.483496470121834	0.664151538282182	0.311013065974025	0.395955979336641	0.288252465435923	0.817941073784378	NA	NA	0.0155995586267544	0.367555046794795	84.4030926980599
a9196	loss_cnaOV84	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	1.78111228434776	1.62586758407588	0.155244700271885	3.66055855360753	1.76359489956529	0.0660089591329122	0.0424101125547873	0.0880274150884374	0.818238907480204	NA	NA	0.61680575320331	0.931159462558137	84.4218523364376
a9197	loss_cnaOV85	1018	ABT-888	PARP1, PARP2	7	24	1.6094379124341	NA	4.43724827537305	4.25943303004683	0.177815245326224	1.01264057743524	0.740552849716437	0.221044133226862	0.175595615353066	0.240111486161063	0.818408811070916	NA	NA	0.227642488455163	0.677123611351942	84.4218523364376
a9198	gain_cnaOV4_(KRAS)	272	AR-42	HDAC	7	23	1.63315443905142	NA	0.445646163316083	0.249278700196351	0.196367463119732	2.14229334369024	1.77212330735001	0.105706580263324	0.0916622663736032	0.110809141951513	0.818436887662833	NA	NA	0.488572104851796	0.830497537056926	84.4218523364376
a9199	gain_cnaOV51_(MYC)	1053	MK-2206	AKT1, AKT2	8	24	1.38629436111989	0.693147180559945	1.54574606144363	1.23127341864945	0.314472642794184	0.980624188309545	1.28381636590377	0.257800233189197	0.320686198181884	0.2449514207375	0.818508341635197	NA	NA	0.0992471914677713	0.479945912468632	84.4218523364376
a9200	gain_cnaOV49	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.43861058215764	2.35361764457288	0.0849929375847673	1.07349526869829	0.861781119004185	0.0968595911507885	0.0791740215938066	0.0986247385913715	0.818591045287017	NA	NA	0.609852962729314	0.90520085932637	84.4218523364376
a9201	loss_cnaOV84	1018	ABT-888	PARP1, PARP2	6	25	1.6094379124341	NA	4.31103828532251	4.29683603747201	0.0142022478505037	1.04724679495244	0.748693779547668	0.0175753730958562	0.0135615099697189	0.0189693680360002	0.81871796939991	NA	NA	0.227643990982851	0.975961670132022	84.4218523364376
a9202	gain_cnaOV51_(MYC)	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	1.6094379124341	NA	1.3733398052391	1.32826573749506	0.045074067744044	0.788149974346874	1.50076277136093	0.0330625948763076	0.057189709079666	0.0300341057255636	0.818849877458264	NA	NA	0.582956747965989	0.915238582934139	84.4218523364376
a9203	loss_cnaOV83	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	2.90312767448295	3.02960095482372	-0.126473280340774	0.991565034130672	1.71311917659097	0.0773342768047397	0.127549153093782	0.0738263175551217	0.818967977455133	NA	NA	0.665158257382666	0.823962303625828	84.4218523364376
a9204	gain_cnaOV95_(MECOM)	224	AS605240	PI3Kgamma	9	23	2.99573227355399	2.32630161961136	3.4798200310856	3.33412408736285	0.145695943722752	1.57743346358391	1.71739530076827	0.0866612650066323	0.0923626555960927	0.0848354153860651	0.819387856233451	NA	NA	0.631613171219935	0.821773500626937	84.4218523364376
a9205	loss_cnaOV21, loss_cnaOV22	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	3.5471460660155	3.56264537927679	-0.0154993132612926	1.28074796842845	0.894818179626956	0.0167634282780956	0.0121017668138964	0.0173211872693	0.819407795739613	NA	NA	0.144933270382159	0.985377752579195	84.4218523364376
a9206	SMARCA4_mut	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	3.97299334400072	3.83568070000488	0.137312643995835	1.13367240893263	0.862855390109959	0.153904089346876	0.121121977490055	0.159137493454537	0.819440900983772	NA	NA	0.940335079902156	0.856559058094688	84.4218523364376
a9207	PTEN_mut	1170	CCT018159	HSP90	4	29	2.30258509299405	NA	3.12799340718109	3.77316129341261	-0.645167886231518	0.346100369900347	1.2733463813943	0.5310262242784	1.86410631811021	0.506671158498965	0.819519410497158	NA	NA	0.200460427913427	0.0409939238336583	84.4218523364376
a9208	loss_cnaOV34	1010	Gefitinib	EGFR	5	25	-0.693147180559945	NA	0.809818228627119	0.948547560479066	-0.138729331851947	1.09059682942609	1.30852420899711	0.108410580896693	0.127204965307804	0.106019690654614	0.819597567403964	NA	NA	0.957720404979269	0.809779852100011	84.4218523364376
a9209	MLL2_mut	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	3.82806387829028	4.35010496478087	-0.522041086490591	1.1394408254774	0.760178134121134	0.658988726622819	0.458155504715981	0.686735204629557	0.819614637326291	NA	NA	0.227648333348693	0.51296633144163	84.4218523364376
a9210	loss_cnaOV57_(ZNRF3)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.74301677966021	1.52527020250277	0.217746577157433	2.09550702712024	0.79491120449963	0.201399601443964	0.103911165335805	0.273925661035936	0.819848675851291	NA	NA	0.457620793710924	0.850168625083879	84.4218523364376
a9211	loss_cnaOV54	291	KIN001-266	MAP3K8 (COT)	10	22	2.99573227355399	NA	3.24105666232571	3.33034325130447	-0.0892865889787653	0.748522347489813	1.23971001668757	0.0800558524142714	0.119283798644342	0.0720221566147649	0.819900568410968	NA	NA	0.951191579188288	0.803198956931287	84.4218523364376
a9212	gain_cnaOV26	207	AS601245	JNK 	3	15	2.07944154167984	NA	1.81006859731336	2.03015094347343	-0.220082346160073	1.42845058291531	0.921614393310394	0.220274030832633	0.154070675452356	0.238800899549266	0.819906170450837	NA	NA	0.483950290826845	0.8184285398647	84.4218523364376
a9213	gain_cnaOV51_(MYC)	1042	BIRB 0796	p38, JNK2	8	25	2.30258509299405	NA	4.44725354640527	4.38157697046974	0.0656765759355356	1.09312144806598	0.789035365275443	0.075745213990919	0.0600816826453592	0.0832365427785466	0.819933326872476	NA	NA	0.870197843888833	0.878297079491833	84.4218523364376
a9214	loss_cnaOV16, loss_cnaOV17	1495	AZD-2281	PARP1, PARP2	6	27	2.30258509299405	NA	3.58574041115377	3.55579100405288	0.0299494071008906	1.52154697345503	0.757568080083351	0.0323943543137695	0.0196835244809323	0.0395336180183243	0.820047911821361	NA	NA	0.144935737298322	0.964201101628669	84.4218523364376
a9215	gain_cnaOV49	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.257467628674702	0.395654147092864	-0.138186518418162	1.47230071193933	0.862850538410047	0.150535701481444	0.0938575369131902	0.160151164386818	0.820110810671294	NA	NA	0.910158778582391	0.886906647050873	84.4218523364376
a9216	loss_cnaOV81_(RB1)	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.67336480304811	2.88583655647614	-0.212471753428026	1.59649541566483	1.06239197561467	0.188487086257674	0.133086353611323	0.199993748357423	0.820240100246109	NA	NA	0.393316381437616	0.811197555877393	84.4218523364376
a9217	loss_cnaOV41	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.44321483087813	2.52333884466204	-0.0801240137839105	0.45532070051582	0.65707132762447	0.126400067385698	0.175972701643348	0.121941120264044	0.820310996058884	NA	NA	0.858866028382626	0.747316908335666	84.4218523364376
a9218	PIK3R1_mut	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	4.509450606131	4.60306433869222	-0.093613732561213	0.494598248641582	1.00361124129986	0.0983744412380155	0.189272268590364	0.0932768872137842	0.820349298714547	NA	NA	0.94344907572202	0.755645613687459	84.4218523364376
a9219	loss_cnaOV33_(ZFHX3)	1036	PLX4720	BRAF	4	29	2.30258509299405	NA	4.25558053785657	4.31510577040533	-0.0595252325487605	1.84699957485206	1.25097252224016	0.0450790501610095	0.0322280705200098	0.0475831654896517	0.820478546061798	NA	NA	0.373570572041824	0.953664376535898	84.4218523364376
a9220	loss_cnaOV87, loss_cnaOV88	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.37729112267176	4.41244587550603	-0.0351547528342646	0.651657651523029	0.636077855655557	0.0551768763801357	0.0539466585746401	0.0552680029994651	0.820669896357015	NA	NA	0.273694982006741	0.935830479652331	84.4218523364376
a9221	SMARCA4_mut	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-0.135877783094477	-0.352235539727931	0.216357756633454	0.662691768179125	1.45494215307488	0.152659478023465	0.326483241564837	0.148705401225886	0.820769187715792	NA	NA	0.889550773066381	0.664719703769355	84.4218523364376
a9222	NF1_mut	308	XL-880	MET	4	28	1.63315443905142	NA	0.416467992383848	0.22975988761194	0.186708104771908	0.333884074882877	1.02390122722827	0.191087949912331	0.559200389648423	0.182349722616636	0.820860046297584	NA	NA	0.370860190827194	0.477323632098622	84.4218523364376
a9223	loss_cnaOV41	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	4.00150544985874	3.90415600775179	0.0973494421069541	0.909808391838589	1.27507757484239	0.0790716022585222	0.106999938646669	0.0763478583795086	0.820904922926602	NA	NA	0.700362828479938	0.843955496753211	84.4218523364376
a9224	gain_cnaOV51_(MYC)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	2.30258509299405	NA	2.03485163459164	2.21265007339013	-0.17779843879849	0.905109449660973	1.41551020115816	0.135658072691955	0.196438606253738	0.125607317173	0.821080939123093	NA	NA	0.688195939989781	0.687421729530587	84.4218523364376
a9225	gain_cnaOV50	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	1.40576229563173	1.78358516649535	-0.377822870863621	1.05570127066063	1.76581166269633	0.220945441507396	0.357888051633384	0.213965554110509	0.821248019367622	NA	NA	0.231663306068059	0.566710541964026	84.4218523364376
a9226	loss_cnaOV81_(RB1)	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.65150524393834	4.46741389722816	0.184091346710177	0.275143302751749	0.734323055379532	0.261821934222505	0.669074423651426	0.250695310955516	0.821254290232496	NA	NA	0.0829898122315196	0.362915936417233	84.4218523364376
a9227	loss_cnaOV54	1032	Afatinib	ERBB2, EGFR	10	21	-0.693147180559945	NA	0.482092249412304	0.29757372518611	0.184518524226194	2.01353613865268	1.51800484374725	0.109348486411157	0.0916390427189759	0.121553317162482	0.821285321751811	NA	NA	0.838114358124489	0.800839443214847	84.4218523364376
a9228	ARID1A_mut	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-2.59086295881831	-2.80312303375661	0.212260074938296	1.34688905749521	1.20456399474503	0.171243305997535	0.157592842377851	0.176213199019969	0.821296973241622	NA	NA	0.38350253292591	0.765765235122764	84.4218523364376
a9229	loss_cnaOV38	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	2.29724579976014	2.09472999778377	0.202515801976371	1.67845915962969	1.29687370020329	0.147123484243786	0.120655781711752	0.156156919478455	0.82142367135124	NA	NA	0.893374897263117	0.834220464709368	84.4218523364376
a9230	loss_cnaOV85	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	3.45688863992762	3.5634653164483	-0.10657667652068	2.04189286757703	1.62933866853256	0.0618617852035241	0.052195038345546	0.0654110029909662	0.821435565170145	NA	NA	0.700143339950867	0.902080105043263	84.4218523364376
a9231	PIK3CA_mut	292	Masitinib	KIT	6	26	2.99573227355399	NA	3.59802747086054	4.10940340872914	-0.511375937868596	0.79086721594385	1.08129124670814	0.492397638342218	0.646601512313671	0.472930803264538	0.821473559129708	NA	NA	0.106505076505279	0.215377618965187	84.4218523364376
a9232	gain_cnaOV51_(MYC)	1066	AZD6482	PI3Kbeta	8	25	1.6094379124341	NA	2.44641827107608	2.3575761658742	0.0888421052018833	1.46463342044444	1.27080334904608	0.0674544975631309	0.0606582534317185	0.0699101912727659	0.821484474043584	NA	NA	0.111837894714771	0.880490418294867	84.4218523364376
a9233	loss_cnaOV81_(RB1)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.58170399863025	3.47596743592219	0.105736562708062	0.747328999053072	1.15831778416568	0.0941722290915334	0.141485962463706	0.0912845888697312	0.821561697147302	NA	NA	0.728272401186875	0.816901999018364	84.4218523364376
a9234	gain_cnaOV96	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.58877616643407	1.27005092404998	0.318725242384084	1.51329080617013	1.18645550615069	0.26059324873347	0.210617312339801	0.268636489722358	0.821876690731814	NA	NA	0.0992583300306408	0.709449918096336	84.4218523364376
a9235	RB1_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	1.50273830869952	1.39898425186963	0.103754056829888	0.536213347676169	1.52587734796159	0.0701496089526999	0.193493983839706	0.067996328124598	0.821963367148062	NA	NA	0.478910995509985	0.813714798099922	84.4218523364376
a9236	loss_cnaOV39	329	QL-XI-92	DDR1	9	23	2.32630161961136	NA	4.68665345878394	4.47381306581882	0.212840392965123	1.12424743690289	0.980461946257206	0.208506177666949	0.189318103807702	0.217081747820622	0.822116582595882	NA	NA	0.193708274703899	0.626368223755579	84.4218523364376
a9237	RB1_mut	1030	KU-55933	ATM	3	30	2.30258509299405	NA	3.96341421089334	4.16975279815444	-0.206338587261099	1.11741026368724	1.03060063368932	0.199087675309001	0.184657859307845	0.20021197398497	0.82211756634169	NA	NA	0.53183753439554	0.783896108998347	84.4218523364376
a9238	NF1_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	4	27	2.30258509299405	NA	1.20553572429413	1.43917152152859	-0.233635797234451	0.826309842939797	1.53459880698916	0.158165348867215	0.282745993201818	0.152245522523791	0.822134518153596	NA	NA	0.47891177935186	0.660150026042545	84.4218523364376
a9239	loss_cnaOV41	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	1.65002184473532	1.22320231656836	0.426819528166966	2.24370804981866	2.35560974234406	0.18232370150602	0.190229530175043	0.181192801377294	0.82231025733212	NA	NA	0.366056198113983	0.712194073024712	84.4218523364376
a9240	loss_cnaOV81_(RB1)	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.10214405622525	1.91608708480467	0.186056971420577	0.746675847473289	1.40270027436922	0.137666582637499	0.249180380013876	0.132642001160401	0.822361003963834	NA	NA	0.83991308291337	0.697336512712721	84.4218523364376
a9241	gain_cnaOV19	178	BAY 61-3606	SYK	3	16	2.07944154167984	NA	2.86692828389462	2.67935547672787	0.187572807166756	1.63515371885344	1.30540848830017	0.139108314820577	0.114712644446836	0.143688974637359	0.82242585651689	NA	NA	0.941709392122563	0.865211832867	84.4218523364376
a9242	SMAD4_mut	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.32161243176214	3.5076106953262	-0.185998263564069	0.489715586328996	1.15510573030691	0.165780037423233	0.379808747682197	0.161022717387654	0.822669395034823	NA	NA	0.728275431817198	0.624950575125905	84.4218523364376
a9243	loss_cnaOV52, loss_cnaOV53	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.63519610910745	-1.54979793789963	-0.0853981712078262	0.447880879683685	1.49981627403714	0.0642370082618187	0.190671616230053	0.0569390882644279	0.822884263068119	NA	NA	0.62541755297082	0.851129215661496	84.4218523364376
a9244	SMARCA4_mut	1133	JNJ-26854165	MDM2	3	30	2.30258509299405	NA	2.85816790142032	3.08882543156458	-0.230657530144268	0.738847698496476	0.935038453622612	0.249726818782024	0.312185489125359	0.246682400334054	0.82297572591159	NA	NA	0.241298951275768	0.653868824342829	84.4218523364376
a9245	gain_cnaOV19	282	EKB-569	EGFR	3	29	0.916290731874155	2.99573227355399	1.96693860535901	1.65429819605639	0.312640409302625	1.62867291323854	1.48326454196868	0.209348215357771	0.191960219121563	0.210778590370446	0.823017905589532	NA	NA	0.32903555726874	0.775779593567326	84.4218523364376
a9246	loss_cnaOV20	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	3.67946144459957	3.7997419591826	-0.120280514583031	0.258819328575748	1.05673322446249	0.121163813691979	0.464727712744334	0.113822970451424	0.823073651692652	NA	NA	0.809904598014304	0.704626599070757	84.4218523364376
a9247	loss_cnaOV70	276	CAY10603	HDAC6	3	28	2.99573227355399	NA	1.59372621483575	1.41598997248354	0.177736242352205	1.71658988871659	1.8109855611144	0.0984888006601096	0.103540305998825	0.0981433790354648	0.82308559997448	NA	NA	0.616630332861352	0.87813813576689	84.4218523364376
a9248	loss_cnaOV52, loss_cnaOV53	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.98936304983497	-4.53435925033816	-0.455003799496802	0.813902381190758	2.33173051370909	0.219077455698844	0.559039769402223	0.195135671477329	0.823153282273803	NA	NA	0.354422653327787	0.536790137424118	84.4218523364376
a9249	gain_cnaOV94	1004	Vinblastine	Microtubules	7	24	-2.30258509299405	NA	-3.23208874226782	-3.33942534038814	0.107336598120322	1.84273936088781	1.83636302186192	0.0584086238274354	0.0582483884582619	0.058450642298107	0.82315883904175	NA	NA	0.141620203984225	0.894810789771212	84.4218523364376
a9250	gain_cnaOV19	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.83922761566453	-4.0093155266242	0.170087910959668	1.84878016791723	1.8405650799818	0.0923621071099587	0.0920000732976724	0.0924107019140828	0.823178594912148	NA	NA	0.594057162292842	0.893554332259887	84.4218523364376
a9251	loss_cnaOV35	1259	BMN-673	PARP1	5	28	2.30258509299405	NA	1.99351056919243	1.88377929903107	0.109731270161355	1.69421840553141	1.33943426286402	0.0789257859034844	0.0647680781905662	0.0819235950607412	0.82338550081801	NA	NA	0.0351545529046599	0.896173510224656	84.4218523364376
a9252	gain_cnaOV18_(CCNE1)	238	CAL-101	PI3Kdelta	4	28	2.99573227355399	2.32630161961136	4.32707134706353	4.39581503799843	-0.0687436909349	1.1514869530639	0.974123779041998	0.0692083359942726	0.0596999303830456	0.0705697698936227	0.823494341985762	NA	NA	0.51376946991179	0.915445089652744	84.4218523364376
a9253	gain_cnaOV19	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	3.01503544027534	2.54297990397007	0.472055536305268	0.717921902836779	2.424219894385	0.200930855384266	0.657530484081903	0.194724718412982	0.823604305987058	NA	NA	0.388535880032044	0.461025864808916	84.4218523364376
a9254	loss_cnaOV83	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	5.12920439183822	5.00576532291298	0.12343906892524	1.63259642845928	1.08576386674299	0.102822893633813	0.0756090524109089	0.11368868748186	0.823829866685844	NA	NA	0.802702494083947	0.893649195064098	84.4218523364376
a9255	KRAS_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	7	25	1.65632149833295	0.0237165266173161	4.44846442729745	4.45290559355791	-0.0044411662604622	0.468440558753591	0.581895191475787	0.00791591474384801	0.00948074665498455	0.00763224430364966	0.823938390656443	NA	NA	0.367441521810431	0.983628335816398	84.4218523364376
a9256	gain_cnaOV51_(MYC)	1013	Nilotinib	ABL	6	15	0.693147180559945	NA	3.2471512077336	3.25018754753841	-0.00303633980481566	1.20167263272089	0.979720317623898	0.00291194326258725	0.00252676121777077	0.00309919040178696	0.823998527381059	NA	NA	0.568906396306665	0.995748670999288	84.4218523364376
a9257	gain_cnaOV96	151	QS11	ARFGAP	4	15	2.32630161961136	NA	4.11296311176032	3.67446384020345	0.438499271556868	0.309573608786975	1.60943882465404	0.299047418030423	1.41646205978304	0.272454761771467	0.824072629460385	NA	NA	0.0670612446009864	0.336886900517232	84.4218523364376
a9258	loss_cnaOV84	1009	ATRA	Retinoic acid and retinoid X receptor agonist	6	25	2.30258509299405	NA	4.54012803651115	4.50483361951968	0.0352944169914702	1.18365038606613	0.867370381963244	0.0379668875609152	0.0298182786124638	0.040691286819805	0.824137898333701	NA	NA	0.530743952343241	0.947307424789702	84.4218523364376
a9259	loss_cnaOV36	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.59632152652853	-2.07575470853709	0.479433182008561	0.55674731971896	1.61695386638941	0.305948931730844	0.861132447392066	0.296503933707839	0.824338023746967	NA	NA	0.0388600271695294	0.316355106199223	84.4218523364376
a9260	SMAD4_mut	306	TG101348	JAK2	3	29	2.32630161961136	NA	3.04466036896682	2.80123774747937	0.243422621487451	0.192713627901956	1.45496496904381	0.173068515773789	1.26313133190193	0.167304798855347	0.82437924321889	NA	NA	0.629325492413077	0.412022752464013	84.4218523364376
a9261	gain_cnaOV50	1527	GDC0941 (rescreen)	PI3K	4	27	1.38629436111989	NA	0.470079082125197	0.36927417318976	0.100804908935437	1.27511860028967	0.867704657939258	0.109776748095852	0.0790553199620306	0.116174216668194	0.82450188098063	NA	NA	0.910162900219428	0.887016127378301	84.4218523364376
a9262	loss_cnaOV39	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	10	23	1.6094379124341	NA	2.56776379006116	2.24658028345217	0.321183506608989	1.7883795516388	1.45372045893869	0.206111311696045	0.179594709811276	0.220938973950654	0.824504519243733	NA	NA	0.244596781252095	0.624230411096551	84.4218523364376
a9263	loss_cnaOV59	279	BIX02189	MAP2K5 (MEK5)	4	28	2.99573227355399	NA	4.47678634181379	4.42466826131499	0.0521180804987988	1.25369240310286	0.663266434022424	0.0700784973433214	0.0415716649233958	0.0785778954359642	0.824529446196257	NA	NA	0.52660952437147	0.939794092350192	84.4218523364376
a9264	loss_cnaOV87, loss_cnaOV88	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.63001605005322	3.5355130129739	0.0945030370793227	0.911863515460288	0.911105467559644	0.103717732880509	0.103637260924536	0.103723488052865	0.82463588835914	NA	NA	0.664996400125211	0.87749503555071	84.4218523364376
a9265	loss_cnaOV1	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.61128954241387	4.37727865274023	0.234010889673649	0.343157608919148	0.797863582637555	0.301904306041551	0.681934142188246	0.293296867742807	0.824649404460666	NA	NA	0.0441957007752932	0.391534960342763	84.4218523364376
a9266	gain_cnaOV94	179	5-Fluorouracil	DNA antimetabolite	6	25	3.46573590279973	NA	3.93976919475306	3.89366051663726	0.0461086781157922	1.61752948413163	1.75183336763342	0.0266613260494732	0.0285056183322343	0.02632024196347	0.824712779661067	NA	NA	0.149502048615978	0.952316406083987	84.4218523364376
a9267	KRAS_mut	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	1.64224970119825	1.37221458190244	0.27003511929581	1.96908713305541	1.75537704684938	0.149880126010521	0.137137211839275	0.153833115102239	0.824814083927222	NA	NA	0.616636633623109	0.751224615485267	84.4218523364376
a9268	loss_cnaOV81_(RB1)	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	4.01503955376469	3.90575649021413	0.109283063550563	0.912085787974009	1.26276572370108	0.0887665105394693	0.119816649915476	0.0865426274243979	0.824868237538947	NA	NA	0.700374615323985	0.841025936946251	84.4218523364376
a9269	loss_cnaOV70	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	1.49954345370277	1.57267853025426	-0.0731350765514889	1.02682505989197	1.09017951707214	0.0674487891662221	0.0712244757244074	0.06708535191333	0.824975275144553	NA	NA	0.457654417169126	0.917039788428495	84.4218523364376
a9270	loss_cnaOV56	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.62977257560723	3.53553819998555	0.0942343756216806	1.17418070398776	0.889399801493561	0.103422588856703	0.0802554285738482	0.105952773391037	0.825009140638973	NA	NA	0.664997567397779	0.903725713325898	84.4218523364376
a9271	loss_cnaOV40	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-2.37708288361118	-2.3126215280557	-0.0644613555554887	0.98692164452336	0.70916254632753	0.0842040724671473	0.0653155758749427	0.0908978567597913	0.825028562808639	NA	NA	0.677320846259091	0.908624682286812	84.4218523364376
a9272	loss_cnaOV36	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	1.76053820493476	1.53352931756946	0.227008887365305	2.60014698128923	0.762546502365777	0.209871520986931	0.0873061749965948	0.297698417946993	0.825079826159211	NA	NA	0.45765509209247	0.894040127862731	84.4218523364376
a9273	loss_cnaOV55	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-3.9824758586786	-4.25043429399098	0.267958435312376	0.782936784991881	1.47422998188318	0.199212162662157	0.342247855061701	0.181761623766521	0.825120803237327	NA	NA	0.220191962837102	0.518636943028721	84.4218523364376
a9274	loss_cnaOV36	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.60031565220287	3.47774963599327	0.122566016209598	0.519776492718538	1.15498298082933	0.109163677970485	0.235805231530484	0.106119326642882	0.825151877011083	NA	NA	0.728282150562054	0.755739074999026	84.4218523364376
a9275	RB1_mut	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	3.93523857074113	3.89774986862294	0.0374887021181962	0.875922100016022	1.09623584871244	0.0346036277529034	0.0427991280474719	0.0341976611713875	0.8253462337527	NA	NA	0.318938026705972	0.949875592143611	84.4326328770542
a9276	SMARCA4_mut	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	1.8182154183895	2.33075093089586	-0.512535512506364	1.80609348869504	1.79828080681189	0.284934143462225	0.283781274731624	0.285014170514905	0.825556117948337	NA	NA	0.112364960255203	0.678182632427521	84.4436032053668
a9277	gain_cnaOV49	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	0.783732486305395	1.02698243052248	-0.24324994421709	1.11375197277404	1.5874297062035	0.155896343476808	0.218405848127231	0.153235096500019	0.825647615501173	NA	NA	0.792123073872876	0.754206818219217	84.4436032053668
a9278	loss_cnaOV52, loss_cnaOV53	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	2.8176833795929	2.67014682724038	0.147536552352525	0.498458113475825	1.51717535283241	0.109401127219366	0.295985857916385	0.0972442322353115	0.825757724711505	NA	NA	0.941712961245378	0.753726436397792	84.4436032053668
a9279	loss_cnaOV83	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.46601020087817	4.38526434387838	0.0807458569997914	1.00332962072334	0.844986200079966	0.093127745373099	0.0804778961290694	0.0955587878147003	0.825957398723544	NA	NA	0.870205393489816	0.871936994089976	84.4436032053668
a9280	loss_cnaOV1	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-2.88460914277229	-3.36132149774547	0.476712354973183	2.36244484142953	1.78698752912035	0.260145278698524	0.201787718643506	0.266768708345629	0.826074004180698	NA	NA	0.141631759507458	0.76347784977057	84.4436032053668
a9281	loss_cnaOV83	1061	SB590885	BRAF	5	28	1.6094379124341	NA	3.75559938030892	3.95824347496109	-0.202644094652165	2.17875268769957	1.10120160609005	0.15687243395741	0.0930092230275693	0.18402088548679	0.826087820707568	NA	NA	0.575163840320499	0.847952713209343	84.4436032053668
a9282	RB1_mut	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	3.93560338054297	3.97328300983985	-0.037679629296882	1.41800167480661	1.15739909175758	0.0320071535666576	0.026572344706166	0.0325554336142283	0.826107094002639	NA	NA	0.0845247565898041	0.968106341226103	84.4436032053668
a9283	loss_cnaOV87, loss_cnaOV88	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.88878790349661	4.80379737421944	0.0849905292771673	0.475534649885913	0.768975828483924	0.112872335920115	0.178726259584991	0.110524318358264	0.826329352337354	NA	NA	0.766457232108007	0.8003242255975	84.4436032053668
a9284	loss_cnaOV70	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.90255195492924	5.7594662421713	0.14308571275794	0.322692743127286	0.581748849140203	0.252048601985423	0.443411622372617	0.245957878506187	0.826509626456312	NA	NA	0.112612275084698	0.548216394816225	84.4436032053668
a9285	gain_cnaOV96	179	5-Fluorouracil	DNA antimetabolite	4	27	3.46573590279973	NA	4.24892019755382	3.85127582571239	0.397644371841429	1.60925981516141	1.73677811872759	0.230648974665429	0.247097683105661	0.22895519442216	0.826586519884538	NA	NA	0.149509603883402	0.67119022321083	84.4436032053668
a9286	loss_cnaOV39	256	JW-7-24-1	LCK	9	23	2.32630161961136	NA	2.04145591430394	1.89938745089984	0.142068463404101	1.27579688406445	1.37784827420095	0.105127788072166	0.111356647111017	0.103108931559602	0.826594949762793	NA	NA	0.839919760775299	0.785513707508015	84.4436032053668
a9287	loss_cnaOV57_(ZNRF3)	1059	AZD8055	MTORC1/2	4	29	0.693147180559945	NA	0.518962812764888	0.248318731092428	0.27064408167246	1.38860306148895	1.11511548902427	0.236485640565535	0.194903849183695	0.24270497929257	0.826602525961881	NA	NA	0.148888233711363	0.729935094332314	84.4436032053668
a9288	loss_cnaOV38	302	PI-103	PI3Ka, PRKDC (DNAPK)	8	24	2.32630161961136	NA	1.27885183049112	1.29357321362889	-0.0147213831377608	2.12476699678594	2.40988037332545	0.0062738835239269	0.00692846940865955	0.00610876095789206	0.826610440777423	NA	NA	0.366076510173769	0.987158930664154	84.4436032053668
a9289	loss_cnaOV70	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	-0.137351234143115	-0.159965907671688	0.0226146735285727	1.68779268112241	1.61713975367437	0.0139415065649115	0.0133989640916878	0.013984365591897	0.826721665943048	NA	NA	0.102429090467739	0.984033087189638	84.4458736424684
a9290	loss_cnaOV39	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	-0.719955773186858	-0.515600769090905	-0.204355004095953	2.43211573187575	1.6843072546943	0.10828974880654	0.0840235525874198	0.121328815467843	0.827107411084424	NA	NA	0.044499474559183	0.868457094797555	84.4761815444931
a9291	loss_cnaOV85	153	Midostaurin	KIT	6	13	-0.669430653942629	NA	0.237642018092603	0.0638172177457723	0.173824800346831	1.64682107942886	1.19825070783827	0.129161500064257	0.105551721749345	0.14506546852822	0.827366948626703	NA	NA	0.871166753791217	0.822865908592052	84.4875628013681
a9292	loss_cnaOV70	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.25321514347162	2.40804904586322	-0.154833902391593	0.664860330998296	0.966342390650464	0.163115735106217	0.232881847769603	0.160226751811406	0.827488932880898	NA	NA	0.736203614918372	0.739358296480717	84.4875628013681
a9293	loss_cnaOV85	303	PIK-93	PI4K, PI3K	7	25	2.99573227355399	NA	2.89382386757178	2.90854266878118	-0.0147188012093977	0.912436109393469	1.33042845907296	0.0117002492598505	0.0161313225746643	0.0110632038190567	0.827511057521795	NA	NA	0.23411098049977	0.973520147261463	84.4875628013681
a9294	loss_cnaOV83	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.60165381213362	4.5039549616341	0.0976988504995253	0.388744868483095	0.622459092493921	0.161973865776215	0.251318688477489	0.156956258937577	0.827621786201988	NA	NA	0.616988764791906	0.683464331656703	84.4875628013681
a9295	loss_cnaOV82	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.33160607869705	-2.10277282664774	-0.228833252049314	1.04207714832262	1.31806882747226	0.175751200879026	0.219593388471914	0.17361252104578	0.827664065166869	NA	NA	0.609445470752681	0.749843064494956	84.4875628013681
a9296	gain_cnaOV96	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	0.943664735659319	0.841084389924785	0.102580345734534	0.604214879252217	2.20628734209182	0.0489852721047297	0.169774610419208	0.0464945538949047	0.827755012863924	NA	NA	0.418689844222847	0.847987025546165	84.4877571080383
a9297	loss_cnaOV35	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-1.07457457119875	-1.20596457657874	0.131390005379987	1.15302847837892	1.38427679998633	0.0978112035367049	0.113952090380901	0.09491599178812	0.827872557131552	NA	NA	0.0509515747879918	0.835212697054735	84.4906657544098
a9298	loss_cnaOV84	328	SNX-2112	HSP90	6	26	0.940007258491471	NA	0.519598549133545	0.736891494795619	-0.217292945662074	2.62284090405516	2.26453294548421	0.0933355392552485	0.0828464072396152	0.0959548617278391	0.828444063145595	NA	NA	0.94613661567408	0.856757719144824	84.5183958989394
a9299	gain_cnaOV94	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	3.55144089802443	3.64416654475292	-0.0927256467284927	0.731606334572007	0.955893100560077	0.101290526466483	0.126742542193457	0.0970042012795813	0.828495476171281	NA	NA	0.06179927175162	0.822606063812503	84.5183958989394
a9300	gain_cnaOV51_(MYC)	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-2.22390494607862	-2.66049400123477	0.436589055156152	2.20327126259209	1.95739478006925	0.216353283769413	0.198154926526168	0.223045989292311	0.828537165446836	NA	NA	0.349829916818104	0.70820676261006	84.5183958989394
a9301	loss_cnaOV38	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	1.33931807169368	1.75402902080176	-0.414710949108078	4.44605835183619	1.56469082946753	0.176759716420519	0.0932760922799866	0.265043381924342	0.828748928556557	NA	NA	0.616873624235907	0.86538859894083	84.5183958989394
a9302	MLL2_mut	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.33601659916562	4.97254261577494	-0.636526016609317	1.00214132609849	0.832523003278364	0.753005223635144	0.635165919249555	0.764574689351241	0.828835710861768	NA	NA	0.156511543410537	0.386818373489965	84.5183958989394
a9303	gain_cnaOV95_(MECOM)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-3.75467525475348	-4.06381107137238	0.309135816618904	1.49499283839597	1.93016865995578	0.168276363169123	0.206780801004095	0.160160002093282	0.829282924281267	NA	NA	0.594097723052342	0.722603907072392	84.5183958989394
a9304	KRAS_mut	1161	ZG-10	IRAK1	6	17	2.30258509299405	NA	1.26557341785488	1.6877532167153	-0.422179798860418	0.527566063784122	1.40972888514836	0.335822680676645	0.800240629263015	0.299475880297359	0.829321991013789	NA	NA	0.167136422354882	0.30814691583962	84.5183958989394
a9305	loss_cnaOV39	292	Masitinib	KIT	9	23	2.99573227355399	NA	4.18931413829135	3.94473157423907	0.244582564052279	1.20095797662303	0.993309371255621	0.232339455720499	0.203656221793888	0.246229997551627	0.829402790402334	NA	NA	0.106531439225089	0.596897117064303	84.5183958989394
a9306	gain_cnaOV51_(MYC)	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	4.04415344136594	3.92089261890871	0.123260822457233	0.929670148497058	1.72212932628206	0.0784087918924719	0.132585544084105	0.0715746608434706	0.829456378077878	NA	NA	0.745552467336792	0.845423733835826	84.5183958989394
a9307	gain_cnaOV19	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.65191576731153	2.88568300753507	-0.233767240223543	0.531849613451411	0.823002651969791	0.289721913594096	0.439536354471562	0.284041903952605	0.829460417972223	NA	NA	0.0201066596426531	0.542969743696054	84.5183958989394
a9308	loss_cnaOV21, loss_cnaOV22	298	OSI-930	KIT, VEGFR, PDGFR	3	29	2.32630161961136	NA	4.70177661278346	4.42568227909512	0.27609433368834	0.812572741465235	1.00025284411222	0.27920759100824	0.339777991063896	0.276024542507938	0.829563074108383	NA	NA	0.0321704390020413	0.62660634625621	84.5183958989394
a9309	gain_cnaOV94	1373	Dabrafenib	BRAF	7	25	2.30258509299405	NA	3.83848333848664	3.59248253368297	0.246000804803669	1.92008757874026	2.07043337924399	0.120514767581742	0.128119575131602	0.11881609293485	0.829599984608024	NA	NA	0.748750057024119	0.774303605756011	84.5183958989394
a9310	loss_cnaOV55	163	JQ1	BRD4	4	15	0.940007258491471	NA	0.188371543821813	0.0618816580331506	0.126489885788662	0.962887347907067	2.03301055872016	0.0669702122504142	0.131365196628246	0.0622180171402016	0.829661376390234	NA	NA	0.585690121465319	0.862266392032237	84.5183958989394
a9311	loss_cnaOV35	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	1.22236485722195	1.21493339308641	0.0074314641355453	1.48959838036791	1.20902597252276	0.0059509979380165	0.0049889045486944	0.00614665383907245	0.829894696885476	NA	NA	0.269455033394348	0.991989952517206	84.5183958989394
a9312	gain_cnaOV96	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	2.43586691846328	2.50718392318252	-0.071317004719246	0.692927406332265	0.79977813117324	0.0912001106802624	0.102921322013707	0.0891709862266763	0.829941584923837	NA	NA	0.751685131412325	0.866134772226266	84.5183958989394
a9313	loss_cnaOV38	151	QS11	ARFGAP	4	15	2.32630161961136	NA	4.10839359292717	3.67568237855895	0.432711214368217	2.210306921868	1.25103294653272	0.295035822396341	0.195769741336429	0.345883148455436	0.829944452022405	NA	NA	0.0670873587260676	0.728534603611855	84.5183958989394
a9314	gain_cnaOV4_(KRAS)	224	AS605240	PI3Kgamma	8	24	2.99573227355399	2.32630161961136	3.26209305748576	3.41277040955124	-0.150677352065488	1.46000593786375	1.74298553298515	0.0896236745595194	0.103203246067585	0.0864478500905443	0.829948344887356	NA	NA	0.631648978719657	0.81348686346484	84.5183958989394
a9315	loss_cnaOV33_(ZFHX3)	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.90712840892817	2.85244175563613	0.0546866532920425	1.30812241773263	1.10779475434226	0.0484197950356241	0.041805455323387	0.0493653297036166	0.830298115312866	NA	NA	0.393363117189283	0.94071113673944	84.5183958989394
a9316	loss_cnaOV39	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	10	23	-2.30258509299405	NA	-0.268522100050017	-0.360412110461791	0.0918900104117746	1.60836762915228	1.332365654516	0.0648007086156514	0.0571324669473777	0.0689675616451965	0.830469210112604	NA	NA	0.889560976990721	0.876184828205823	84.5183958989394
a9317	gain_cnaOV95_(MECOM)	223	ZSTK474	PI3K	9	23	1.63315443905142	2.32630161961136	0.695174561920957	0.782951722368069	-0.087777160447112	0.884869513341607	1.11144621706232	0.0831387747382752	0.0991978581289707	0.0789756257204395	0.83055241257353	NA	NA	0.773153050013971	0.81756948992308	84.5183958989394
a9318	KRAS_mut	202	GSK-1904529A	IGF1R	3	16	0.0237165266173161	NA	2.53559741879882	2.48402714157466	0.0515702772241675	0.342695645616817	0.823405047496035	0.0659184016392428	0.150484191683692	0.0626305089833881	0.830771200897859	NA	NA	0.751688649561031	0.86145034990254	84.5183958989394
a9319	gain_cnaOV51_(MYC)	206	Ruxolitinib	JAK1, JAK2, TYK2	8	24	1.65632149833295	0.0237165266173161	4.52250684613507	4.42840983587289	0.0940970102621828	0.407988804476711	0.597999054983971	0.168190901540316	0.230636255773911	0.157353108634436	0.830931100266719	NA	NA	0.367473941648134	0.624593679980916	84.5183958989394
a9320	TP53_mut	299	OSI-027	MTORC1/2	22	10	2.99573227355399	NA	1.58470197625254	1.41302406886659	0.171677907385945	1.92258928645315	1.95681592365777	0.0888178642350194	0.0892951545062756	0.0877332943330899	0.830954798038632	NA	NA	0.783770287431165	0.819812873221553	84.5183958989394
a9321	gain_cnaOV95_(MECOM)	153	Midostaurin	KIT	5	14	-0.669430653942629	NA	0.216051280667103	0.0839442525653674	0.132107028101736	1.5185974381377	1.28975089067913	0.0980677768010786	0.0869927900469409	0.102428328645831	0.830973270011571	NA	NA	0.871174966597634	0.867816760296618	84.5183958989394
a9322	loss_cnaOV36	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.11985345282946	3.40150599760784	-0.281652544778385	0.917446574128359	1.72204633843826	0.16760694254692	0.306996126772805	0.163556890712836	0.830979897368546	NA	NA	0.631652353246017	0.674451357635776	84.5183958989394
a9323	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	4.13150266913886	4.00502232353789	0.126480345600966	1.43452995191234	1.52703498172827	0.0838180091687084	0.0881684940996582	0.0828274054716276	0.831096474138067	NA	NA	0.33237705548188	0.842956576113236	84.5183958989394
a9324	gain_cnaOV51_(MYC)	1038	NU-7441	PRKDC (DNAPK)	8	25	0.693147180559945	NA	2.53582337430929	2.53743538823775	-0.00161201392845678	0.97768618444946	1.06216335619813	0.00154453961599176	0.00164880506045456	0.00151767044028591	0.831101647069519	NA	NA	0.397631846771781	0.996891331829754	84.5183958989394
a9325	SMAD4_mut	1143	HG-5-88-01	EGFR, ADCK4	3	19	2.30258509299405	NA	3.38146623730109	3.66124405468519	-0.279777817384095	1.03901640223584	0.895420501766971	0.307178297597948	0.269271800504831	0.312454111595611	0.831139845317391	NA	NA	0.0618086273765987	0.694438686144729	84.5183958989394
a9326	SMARCA4_mut	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.1633359417071	3.31683139058049	-0.153495448873391	0.32677784128842	1.15099732136972	0.137643649026651	0.469724165715119	0.13335864994953	0.831198821895131	NA	NA	0.95119704756959	0.602901822756742	84.5183958989394
a9327	RB1_mut	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.30996976731451	4.29847219095685	0.0114975763576606	0.945032115453606	0.797010447548729	0.0142280926366517	0.0121663340003444	0.0144258790998566	0.831307832081333	NA	NA	0.227702861509565	0.985411483569845	84.5183958989394
a9328	loss_cnaOV42	152	CP466722	ATM	4	28	2.77258872223978	NA	2.59728212472635	2.65400733648278	-0.0567252117564361	1.01382548194476	0.795985329249063	0.0691453402445303	0.05595165318554	0.071264142280048	0.831374716535025	NA	NA	0.558092860020949	0.920353399044199	84.5183958989394
a9329	loss_cnaOV20	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	2.80028594605853	2.85227594516327	-0.051989999104737	1.17723646243446	1.95290315997995	0.0278291908680688	0.0441627495951191	0.0266219033130505	0.83141428872813	NA	NA	0.348961614899632	0.937745917261463	84.5183958989394
a9330	loss_cnaOV16, loss_cnaOV17	277	ABT-869	VEGFR and PDGFR family	6	26	0.0237165266173161	NA	2.81692676979154	2.69275335022953	0.124173419562011	0.862303224105175	0.493793840048176	0.217107155481157	0.144002035584254	0.251468142149963	0.831460128092886	NA	NA	0.137696512761581	0.74580293685178	84.5183958989394
a9331	loss_cnaOV70	295	NVP-BHG712	EPHB4	3	29	2.32630161961136	NA	3.23890711899158	3.25239416919619	-0.0134870502046147	0.509502715431522	1.12613968952419	0.012307061567642	0.0264710075061953	0.0119763563348995	0.831495456249889	NA	NA	0.0637574367058887	0.971807947619736	84.5183958989394
a9332	TP53_mut	293	MP470	PDGFR	22	10	2.99573227355399	NA	4.00859528403686	4.13866710325381	-0.130071819216949	1.72052316390869	1.91256538317641	0.0730612373225134	0.0756001557813682	0.0680090836951804	0.831505648954458	NA	NA	0.624130428611185	0.856425342189659	84.5183958989394
a9333	loss_cnaOV38	1054	PD-0332991	CDK4, CDK6	8	25	1.38629436111989	0.693147180559945	2.60816487854046	2.18047420614883	0.427690672391629	1.9507892951983	1.74729946181511	0.238232478612458	0.219239808955459	0.244772394050497	0.831624214876878	NA	NA	0.112384634017918	0.591377139680001	84.5183958989394
a9334	loss_cnaOV59	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.00281093867116	3.91715760157829	0.0856533370928667	2.33656801469941	1.12597643197265	0.0662117110236382	0.0366577546872248	0.0760702752390711	0.831671790039408	NA	NA	0.575183791230915	0.946750604492845	84.5183958989394
a9335	gain_cnaOV94	305	TPCA-1	IKK	7	25	2.99573227355399	NA	3.23601352843751	3.35016582667277	-0.114152298235254	1.45996372896951	1.17825576403469	0.0920784243990322	0.0781884480896155	0.096882444134509	0.831704526795082	NA	NA	0.993646923239322	0.853677411344819	84.5183958989394
a9336	loss_cnaOV84	272	AR-42	HDAC	6	24	1.63315443905142	NA	0.0567598557363162	0.354682254721281	-0.297922398984965	1.7037898885194	1.88693666481113	0.160556756958381	0.174858649527414	0.157886803802599	0.831721183860215	NA	NA	0.48863340382884	0.717203787671127	84.5183958989394
a9337	gain_cnaOV94	312	AV-951	VEGFR	7	25	-2.05572501506252	NA	0.777858531789053	0.601203929659755	0.176654602129298	0.568288933158102	0.629502392124808	0.285966796866188	0.310853496913252	0.280625783697218	0.831948678256335	NA	NA	0.0156126529359295	0.493417017634013	84.5183958989394
a9338	gain_cnaOV94	1248	FK866	NAMPT	7	25	0	NA	-1.4732473454162	-1.7741886623072	0.300941316890994	2.89946151500924	2.74619806697886	0.10834864008062	0.103792140483036	0.109584709314891	0.832046910453617	NA	NA	0.0456890116182478	0.811430769906154	84.5183958989394
a9339	SMAD4_mut	223	ZSTK474	PI3K	3	29	1.63315443905142	2.32630161961136	0.904275928755676	0.743159754671972	0.161116174083704	1.49074235414077	1.01727002187504	0.152649683847504	0.108077813470704	0.158380931924774	0.832060771646996	NA	NA	0.773156234033384	0.870422672778077	84.5183958989394
a9340	loss_cnaOV70	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.65501821528807	4.47175416281904	0.183264052469028	1.11196104232046	0.636396877966714	0.269522628832438	0.164811576569796	0.287971325463688	0.832063220435909	NA	NA	0.0547107292835153	0.803825616318018	84.5183958989394
a9341	PIK3R1_mut	1375	Temozolomide	DNA akylating agent	5	28	3.40119738166216	NA	5.99779399469268	5.93819180432802	0.0596021903646653	0.188305544573399	0.755097998773913	0.0841911381204111	0.316518509848939	0.0789330530096015	0.83220052721856	NA	NA	0.909184706373047	0.721864859853499	84.5183958989394
a9342	ARID1A_mut	1371	PLX4720 (rescreen)	BRAF	9	24	2.30258509299405	NA	4.37782892054134	4.58469414739603	-0.206865226854692	0.754589243903954	1.06179334468715	0.208603348004064	0.274142824756488	0.194826260580532	0.832368522775085	NA	NA	0.328064679176919	0.540170447854597	84.5183958989394
a9343	gain_cnaOV95_(MECOM)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	8	25	1.6094379124341	NA	2.4696377790466	2.30367528750554	0.165962491541058	1.67313111565784	1.53071148716681	0.106113801854606	0.0991927590061017	0.108421797923681	0.832465283334241	NA	NA	0.244631369061515	0.807813234643534	84.5183958989394
a9344	loss_cnaOV83	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	3.78942530840222	4.07773889742253	-0.28831358902031	1.07643664890658	1.56172065349289	0.191433383195007	0.267840740384652	0.184612778460398	0.832480282747018	NA	NA	0.332383342642161	0.625940315932193	84.5183958989394
a9345	loss_cnaOV39	225	Genentech Cpd 10	AURKA, AURKB	9	23	2.32630161961136	NA	3.07265650003259	2.75473790214815	0.317918597884436	1.93701469839931	1.8345736050463	0.170699841738373	0.164128128788674	0.173292909594878	0.832495945088435	NA	NA	0.34896651393354	0.678291161771792	84.5183958989394
a9346	loss_cnaOV85	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	2.13123409828286	2.34124884489592	-0.210014746613055	0.616204963037939	1.56331807285579	0.147880248377575	0.340819628549672	0.134339102361562	0.832509016672934	NA	NA	0.532273317688422	0.599539502075256	84.5183958989394
a9347	ARID1A_mut	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-3.16523278074229	-3.56052896101003	0.395296180267739	1.28069505437484	1.91127654660594	0.221692756896185	0.308657536325615	0.206823120897763	0.832718422092333	NA	NA	0.684377746337347	0.616878461738053	84.524074764619
a9348	KRAS_mut	224	AS605240	PI3Kgamma	7	25	2.99573227355399	2.32630161961136	3.56314015949008	3.32245012690741	0.240690032582669	1.60869351294305	1.69665513553229	0.143316380896715	0.149618327323478	0.141861494149285	0.832769841950141	NA	NA	0.631658156946195	0.736702568995779	84.524074764619
a9349	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.60519141075461	-2.07480436379858	0.469612953043966	1.1105352382898	1.5959577024464	0.299629056961506	0.422870825573404	0.294251503234771	0.832860678445684	NA	NA	0.0388755948586902	0.555258156400573	84.524074764619
a9350	loss_cnaOV39	1024	CEP-701	FLT3, JAK2, NTRK1, RET	10	21	0.693147180559945	NA	0.134222764296157	-0.296825083818961	0.431047848115118	1.30520698213858	1.72795736085694	0.267949249880206	0.330252484099378	0.249455141590617	0.83292128365008	NA	NA	0.102449429552938	0.448514834711756	84.524074764619
a9351	gain_cnaOV72_(ASXL1)	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.65467167323259	3.53725182591477	0.117419847317823	0.76123392889517	0.994647383850182	0.121453679692013	0.154249361281417	0.118051732930019	0.833038315400595	NA	NA	0.729914820454093	0.772637481994475	84.5269107261652
a9352	gain_cnaOV94	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.38629436111989	0.693147180559945	2.70403932184183	2.85088850499922	-0.146849183157387	1.73386019206977	1.53022011994636	0.093433646862548	0.0846949389743402	0.0959660517093018	0.833211547372092	NA	NA	0.968978744851114	0.843251626452044	84.5354480075464
a9353	PIK3CA_mut	293	MP470	PDGFR	6	26	2.99573227355399	NA	4.11024382230487	4.03516555182768	0.0750782704771913	1.00865199811592	1.89828658235199	0.0421517185168744	0.0744342653535922	0.0395505458317937	0.833550728633144	NA	NA	0.624137142470898	0.894267827721242	84.5498310130739
a9354	loss_cnaOV55	1025	SB 216763	GSK3A, GSK3B	6	17	2.30258509299405	NA	5.07275750076302	4.92014380962985	0.152613691133172	0.747745717320247	0.856651410626692	0.18342650708612	0.204098382107898	0.178151450216519	0.833590383754376	NA	NA	0.457684214906766	0.688087215259783	84.5498310130739
a9355	loss_cnaOV34	1023	GW 441756	NTRK1	5	26	0.693147180559945	NA	2.16875804119427	2.32341298238048	-0.154654941186211	1.50432316129792	1.22353162239704	0.122163232382791	0.102806993314372	0.126400444708755	0.833620640314622	NA	NA	0.845399868949931	0.837024327941267	84.5498310130739
a9356	PIK3R1_mut	1219	PFI-1	BRD2, BRD3, BRD4	5	27	2.30258509299405	NA	2.4899300117562	2.33781827334464	0.152111738411553	0.876221623205299	0.87597024706901	0.173642790086735	0.173599617246507	0.173649434921469	0.83373427425305	NA	NA	0.609906266601254	0.734478427446128	84.5523181204473
a9357	loss_cnaOV20	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.46696266891282	1.50340123145881	-0.0364385625459918	0.704445569907155	1.82538929664833	0.0212012012701193	0.0517265834332585	0.0199620774663783	0.834045570598869	NA	NA	0.318767363302998	0.939388833391546	84.5651807302742
a9358	loss_cnaOV36	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	4.74028410059591	4.51230101176209	0.22798308883382	1.87982125222425	0.932440286349049	0.222800453065801	0.121279131494053	0.244501543070906	0.834112191484784	NA	NA	0.19375901497191	0.854033569532824	84.5651807302742
a9359	loss_cnaOV85	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	1.49487310909995	1.41519942126445	0.0796736878354971	1.60929253423192	1.8528084390115	0.0441375367586827	0.0495085176502877	0.0430015786618525	0.834161806712718	NA	NA	0.616669567659667	0.913413412605355	84.5651807302742
a9360	gain_cnaOV96	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	2.92737643775171	2.5242459758222	0.403130461929505	1.6739888984189	2.43605668887519	0.171634184456519	0.240820272052143	0.165484844326691	0.834263402093682	NA	NA	0.388584420471763	0.660915104779608	84.5651807302742
a9361	PIK3R1_mut	163	JQ1	BRD4	3	16	0.940007258491471	NA	0.0657865825487231	0.0927719561336462	-0.0269853735849231	3.20057749618508	1.63720485815523	0.014281704906291	0.00843140764974079	0.0164825882665226	0.834339633746505	NA	NA	0.585720580569829	0.989812887864997	84.5651807302742
a9362	ARID1A_mut	276	CAY10603	HDAC6	8	23	2.99573227355399	NA	1.52814981490735	1.40016084151251	0.127988973394841	1.59236732086849	1.86697798875565	0.0709267653496905	0.0803765385771891	0.0685540880319356	0.834532485482608	NA	NA	0.616670834115917	0.854303896714112	84.5651807302742
a9363	gain_cnaOV19	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.69418140524589	4.57749813653818	0.116683268707708	0.768334118842716	0.963363047094741	0.12261727492537	0.151865270389735	0.121120764450738	0.834559520192727	NA	NA	0.943456948407736	0.824622042917044	84.5651807302742
a9364	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	266	Zibotentan, ZD4054	Endothelin A Receptor	7	25	2.99573227355399	NA	5.67698657571222	5.72573773164897	-0.0487511559367517	0.476737503264374	0.482637500847946	0.10125622745405	0.102259955642124	0.101009879777474	0.834574113455967	NA	NA	0.384341722058224	0.81644505880353	84.5651807302742
a9365	gain_cnaOV51_(MYC)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	5	14	-0.669430653942629	NA	-3.91338810743918	-4.00712790969892	0.0937398022597438	1.32633421892284	1.97396975907022	0.0508851578751466	0.0706758529806107	0.0474879626848475	0.835033228664117	NA	NA	0.594134544957688	0.908174855673931	84.6026667708621
a9366	gain_cnaOV26	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	2.84854444895005	2.38528114345114	0.46326330549891	1.91106264481706	1.55294840734837	0.290923613274979	0.242411365611334	0.298312103162476	0.835258317472258	NA	NA	0.231313580460415	0.721863349324175	84.610037587639
a9367	loss_cnaOV82	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	1.96319536425501	1.89412623753557	0.0690691267194417	1.52215301133643	1.38122819652083	0.0496631828713736	0.0453759419749791	0.0500055869793416	0.835349777636161	NA	NA	0.0351735837105623	0.945751504728633	84.610037587639
a9368	PIK3CA_mut	277	ABT-869	VEGFR and PDGFR family	6	26	0.0237165266173161	NA	2.50794825505337	2.76405608439988	-0.256107829346512	0.412054634160926	0.590596602350982	0.453470442827147	0.621538524540633	0.433642571472688	0.835506348815758	NA	NA	0.137710997049427	0.237317252411538	84.610037587639
a9369	PIK3CA_mut	200	LAQ824	HDAC	5	14	0.0237165266173161	NA	-2.58358655072498	-2.8057217509328	0.222135200207816	1.34328434511495	1.20529767933927	0.17926442216852	0.165367221776717	0.184299035844479	0.835527946340459	NA	NA	0.383621007499995	0.754806627246106	84.610037587639
a9370	gain_cnaOV19	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.41726165197732	3.21029644360566	0.206965208371665	1.09801298975271	1.24908129045257	0.166963576877483	0.188490673883809	0.165693946385728	0.835568415410783	NA	NA	0.602945662069502	0.782286809302061	84.610037587639
a9371	gain_cnaOV95_(MECOM)	283	GSK2126458	PI3K, MTOR	9	23	-2.05572501506252	0.0237165266173161	-2.62001731813767	-2.77607387171035	0.156056553572681	1.61200953987659	1.83968709029891	0.0875826741198234	0.096808703492306	0.0848277701113429	0.835641017587636	NA	NA	0.697873674648761	0.816024926756288	84.610037587639
a9372	loss_cnaOV84	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.41155339920932	-1.62967033429182	0.218116935082491	1.831734791076	1.1257751844301	0.164475560640925	0.119076700483679	0.193748217316504	0.835845519606582	NA	NA	0.625496830744723	0.812348713763494	84.6217135869045
a9373	MLL2_mut	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	3	28	2.30258509299405	NA	1.08467629674112	1.44377661029375	-0.359100313552625	0.988372139408184	1.50511700313794	0.243408042579469	0.36332500607276	0.238586311100038	0.835963410533536	NA	NA	0.478972462908566	0.611433361989053	84.6246194494198
a9374	loss_cnaOV21, loss_cnaOV22	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	2.45676424272316	2.6007320968203	-0.143967854097138	2.29648160697751	2.35723985522577	0.0611786174387422	0.0626906192759017	0.0610747581659861	0.836301573835489	NA	NA	0.388593336738518	0.925693443787355	84.630557664662
a9375	PIK3CA_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	7	26	1.6094379124341	NA	2.05412106631654	2.42192834445368	-0.367807278137135	1.35493098253824	1.6029377888673	0.236073448426547	0.271458312546746	0.229458236427904	0.836366078597984	NA	NA	0.244647696054713	0.552921384163787	84.630557664662
a9376	gain_cnaOV4_(KRAS)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	8	24	2.32630161961136	NA	5.17682084019178	5.13097855610347	0.0458422840883062	0.63638531209541	0.576817601939757	0.0775340249079794	0.0720354213351695	0.0794744888750707	0.836367468482199	NA	NA	0.0123183981907599	0.859994447580502	84.630557664662
a9377	PTEN_mut	1243	piperlongumine	Increases ROS levels	4	28	2.30258509299405	NA	1.31055202918689	1.65789168767408	-0.347339658487185	0.739782543861819	0.671964914134407	0.511507068848841	0.469515888647493	0.516901479796175	0.836593960180474	NA	NA	0.211543293797188	0.427841661908466	84.630557664662
a9378	loss_cnaOV43_(NF1)	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.44951930975053	2.38316560043317	0.0663537093173665	1.08234286530563	0.928019212628417	0.0698426880749821	0.0613056282295812	0.0715003616459984	0.836713489188221	NA	NA	0.736225905026851	0.902541025333159	84.630557664662
a9379	loss_cnaOV54	230	GSK429286A	ROCK2	10	22	2.99573227355399	2.32630161961136	5.55532201062004	5.53121115702227	0.0241108535977759	1.31330482918682	0.810344584989933	0.0243918601099563	0.0183589164236188	0.0297538282409519	0.836804904210857	NA	NA	0.306845203191655	0.958117431130251	84.630557664662
a9380	PIK3CA_mut	1502	Bicalutamide	ANDR (androgen receptor)	7	25	2.30258509299405	NA	4.41994052390424	4.54311082027838	-0.123170296374143	0.36009490101156	0.648302049297054	0.204667877981526	0.342049543129156	0.189989059124053	0.836945294436244	NA	NA	0.617019891803795	0.520554898513135	84.630557664662
a9381	loss_cnaOV84	179	5-Fluorouracil	DNA antimetabolite	6	25	3.46573590279973	NA	4.20270413485686	3.83055613101235	0.372148003844514	2.24363288664278	1.59304220606397	0.216009590652683	0.16586849214952	0.233608376744772	0.837020827912325	NA	NA	0.149550103670375	0.713859276601912	84.630557664662
a9382	loss_cnaOV54	302	PI-103	PI3Ka, PRKDC (DNAPK)	10	22	2.32630161961136	NA	1.55769251668453	1.16816575473532	0.389526761949212	2.64655626382926	2.19409695651095	0.16653255277157	0.14718249797781	0.177533978520547	0.837204247865249	NA	NA	0.366124296131098	0.690322880330016	84.630557664662
a9383	RB1_mut	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	1.28056168753502	1.77095270503039	-0.490391017495374	2.39656086555291	1.53078065438668	0.305435135739694	0.204622809520107	0.320353550386259	0.837337679137126	NA	NA	0.0423268294390673	0.759334501096882	84.630557664662
a9384	loss_cnaOV55	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	2.53052976033463	2.43021422394907	0.100315536385565	1.90591846715363	1.54042643479556	0.0626745029094141	0.0526336976709083	0.0651219260586622	0.837376605823257	NA	NA	0.231327176385751	0.926463526628456	84.630557664662
a9385	gain_cnaOV51_(MYC)	1129	PF-4708671	RPS6KB1 (p70S6KA)	8	24	2.30258509299405	NA	4.26721213078684	4.17363736665809	0.0935747641287463	1.07445852187015	0.950667902228679	0.0953919180625828	0.0870901595771928	0.0984305496266112	0.837501472487619	NA	NA	0.0493183390281067	0.830418855339087	84.630557664662
a9386	SMARCA4_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.21169376913696	-2.11476405760375	-0.0969297115332117	1.53656671516262	1.28584899604793	0.0743622314479715	0.0630820065127816	0.0753818775230419	0.837518525967656	NA	NA	0.609477698476563	0.92442244276539	84.630557664662
a9387	loss_cnaOV35	164	JQ12	HDAC	3	16	1.63315443905142	NA	1.96440097353389	1.76192282320266	0.20247815033123	2.93962874371231	2.13264965966133	0.0902827871565957	0.0688788170153522	0.0949420592425778	0.837628024561329	NA	NA	0.663603635532795	0.918172569713647	84.630557664662
a9388	loss_cnaOV85	274	PXD101, Belinostat	HDAC	7	23	2.99573227355399	NA	0.871683189182566	0.849611772017553	0.0220714171650128	1.657318187932	2.19856839506945	0.0105383278511856	0.0133175495965283	0.0100389950180811	0.837654259518665	NA	NA	0.418736314808886	0.977744087821292	84.630557664662
a9389	MLL2_mut	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-4.29277566000213	-3.21044651375656	-1.08232914624557	1.41560544161112	1.83399730856243	0.598549511130355	0.764569783663556	0.590147619733392	0.837668784672417	NA	NA	0.141675706272213	0.316124444304602	84.630557664662
a9390	gain_cnaOV94	308	XL-880	MET	7	25	1.63315443905142	NA	0.127121642536134	0.288371892996671	-0.161250250460537	0.227367867432387	1.08608936457957	0.165091089979746	0.709204217295517	0.148468676445383	0.837700827768922	NA	NA	0.370937294082402	0.49545895927214	84.630557664662
a9391	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	1.21697394231954	1.47477031394034	-0.257796371620799	1.54631872054594	1.84050982710155	0.142998698883806	0.166716193883873	0.140067913696923	0.837997709051142	NA	NA	0.616682528204316	0.751590108491884	84.630557664662
a9392	PIK3R1_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	5	27	2.99573227355399	NA	5.69054843311146	5.71961507983898	-0.0290666467275216	0.139416493525198	0.51462802728907	0.0603305665836867	0.208487862465627	0.0564808855837824	0.838080737472705	NA	NA	0.384356989846832	0.80587323542274	84.630557664662
a9393	PIK3CA_mut	1030	KU-55933	ATM	7	26	2.30258509299405	NA	4.07344475049814	4.17187358937793	-0.0984288388797872	0.885338251564752	1.07068097977284	0.0948807056156293	0.111176534737795	0.0919310613892387	0.838107212468965	NA	NA	0.531898317373776	0.807736715840478	84.630557664662
a9394	gain_cnaOV48_(SOX17)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.82492674106948	2.86778532059459	-0.0428585795251126	0.169515089185346	0.837026399635689	0.0529230666205925	0.252830469140429	0.0512033784642474	0.838110266741851	NA	NA	0.0201159153883865	0.81827751558403	84.630557664662
a9395	PIK3CA_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	6	26	2.99573227355399	NA	5.59875535754498	5.74191604522845	-0.143160687683473	0.393566262165901	0.493672735515375	0.299220724130958	0.363752438777707	0.289991075836948	0.838147359854212	NA	NA	0.384357276571894	0.464789826515508	84.630557664662
a9396	ARID1A_mut	1259	BMN-673	PARP1	9	24	2.30258509299405	NA	1.38863344621124	2.09231967512213	-0.703686228910894	1.56274193662405	1.27167159652249	0.520171952981251	0.450289463934811	0.553355308741026	0.838498396395027	NA	NA	0.035178358178235	0.249538981946098	84.630557664662
a9397	loss_cnaOV85	294	MPS-1-IN-1	MPS1	7	24	2.99573227355399	NA	4.17085219260479	4.31680673565242	-0.145954543047623	0.759738733829864	0.839460952717988	0.177215309923985	0.192111493791902	0.173866982823984	0.838506781787172	NA	NA	0.319634483089884	0.671184878061811	84.630557664662
a9398	gain_cnaOV95_(MECOM)	1052	RO-3306	CDK1	8	25	1.6094379124341	NA	3.42644658977403	3.49949896283442	-0.0730523730603938	0.779239779498808	0.94710520763736	0.0801096179177393	0.0937482594989949	0.0771322683808587	0.838666639427679	NA	NA	0.795302049168936	0.830138444024218	84.630557664662
a9399	KRAS_mut	299	OSI-027	MTORC1/2	7	25	2.99573227355399	NA	1.70800623089538	1.48150562199816	0.226500608897215	2.01227191611666	1.91171973814936	0.117221242653944	0.112559643198878	0.118480028414876	0.838674644683761	NA	NA	0.783785520084561	0.796005816897757	84.630557664662
a9400	loss_cnaOV85	275	I-BET	BRD2, BRD3, BRD4	7	24	2.99573227355399	NA	3.96976293001412	3.90530178919756	0.0644611408165612	0.733347900391718	1.33101798426623	0.0523479878439858	0.08789980960214	0.048429954800421	0.838730958839144	NA	NA	0.700413637312816	0.86988604437391	84.630557664662
a9401	loss_cnaOV1	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.50446019210726	-0.763985642181809	0.259525450074549	1.5535733317615	0.868341370215515	0.279676961501761	0.167050659771747	0.298874911384375	0.838912100633231	NA	NA	0.0429877049066428	0.801072391882285	84.630557664662
a9402	PIK3CA_mut	257	NPK76-II-72-1	PLK3	6	26	2.32630161961136	NA	3.01792359273165	3.2785707793887	-0.260647186657048	1.64858925965672	1.1365387838928	0.210761533124958	0.158103169197718	0.229334177021478	0.839000747762755	NA	NA	0.602957082956057	0.725481436005199	84.630557664662
a9403	ARID1A_mut	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.35049418761092	-4.76252670113247	0.412032513521549	2.12548442730281	2.06429072706134	0.19820201285623	0.193853461464504	0.199600040885765	0.839166046131019	NA	NA	0.354554827256562	0.7189809191874	84.630557664662
a9404	loss_cnaOV84	151	QS11	ARFGAP	5	14	2.32630161961136	NA	4.08379262028856	3.65356049633216	0.430232123956397	1.7838299133033	1.35159951795716	0.293709838715714	0.24118449900848	0.318313315623744	0.839317570899222	NA	NA	0.067127109882299	0.641457330486825	84.630557664662
a9405	NF1_mut	298	OSI-930	KIT, VEGFR, PDGFR	4	28	2.32630161961136	NA	4.39976908726194	4.45896569939504	-0.0591966121331042	0.931744565175489	0.998614715230819	0.0596661525459254	0.0635330908766341	0.0592787300549858	0.839332202236704	NA	NA	0.0321850465271998	0.911855706299868	84.630557664662
a9406	loss_cnaOV39	1007	Docetaxel	Microtubules	10	21	-4.38202663467388	NA	-4.40894385948587	-4.76268504547275	0.353741185986883	1.68385634112338	1.28824032804471	0.248616540930087	0.210078008050785	0.274592541691185	0.839346090096157	NA	NA	0.137632127114217	0.566094348929568	84.630557664662
a9407	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.30602022672278	5.16946215355726	0.136558073165522	0.590430208078028	0.800764701771741	0.17597213458712	0.231285715563313	0.170534581336289	0.839521828464046	NA	NA	0.336283819940655	0.668492694761765	84.630557664662
a9408	loss_cnaOV82	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.88163012505994	4.80453783405772	0.0770922910022191	0.814874267927949	0.748445384360163	0.102372545691938	0.094606363259265	0.103003228576424	0.839611458350613	NA	NA	0.766485743559379	0.887554754305013	84.630557664662
a9409	gain_cnaOV96	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.11253803599132	2.32868926098175	-0.216151224990427	0.651457611878295	1.50777876695233	0.152145156857211	0.331796299635237	0.143357387521335	0.839647046153674	NA	NA	0.532301310621739	0.610655534748132	84.630557664662
a9410	loss_cnaOV81_(RB1)	272	AR-42	HDAC	4	26	1.63315443905142	NA	0.376874671608667	0.282516713895922	0.0943579577127445	1.8938674504815	1.85517287233731	0.0507476217127106	0.0498228942520526	0.0508620835932472	0.839792002533884	NA	NA	0.488668233171169	0.930427066829502	84.630557664662
a9411	loss_cnaOV55	329	QL-XI-92	DDR1	7	25	2.32630161961136	NA	4.55606384147333	4.527405390103	0.0286584513703367	1.09256387988455	1.00802109677928	0.0279461762165311	0.0262304583722509	0.0284304083137773	0.839811138250737	NA	NA	0.193781808014696	0.951625328875483	84.630557664662
a9412	loss_cnaOV1	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.49036053119245	4.53206794095998	-0.0417074097675281	0.371316134077599	1.02528654543678	0.0418691793927786	0.11232318216157	0.0406787838513578	0.839846350509841	NA	NA	0.32809663412277	0.88831152645833	84.630557664662
a9413	TP53_mut	226	GSK1070916	AURKB	22	10	0.940007258491471	2.32630161961136	2.28012682086039	2.38842461486816	-0.108297794007776	1.6803813253085	0.685927304623502	0.0744191560178674	0.0644483441803861	0.157885235472904	0.839875415643026	NA	NA	0.821930084078551	0.797728469530758	84.630557664662
a9414	loss_cnaOV21, loss_cnaOV22	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.21242984109924	4.23101392546145	-0.0185840843622129	0.697231851021581	1.00315914658846	0.0188424208702129	0.0266540955278844	0.0185255594044212	0.839969181003084	NA	NA	0.21200017844111	0.969202001027673	84.630557664662
a9415	loss_cnaOV38	286	KIN001-236	TIE2	8	24	2.32630161961136	NA	4.76751290749213	4.80425662883329	-0.0367437213411632	0.944202382948262	0.559760784121777	0.0548816003287098	0.0389150906677775	0.0656418284085609	0.840043357600092	NA	NA	0.763387568593592	0.919421389700835	84.630557664662
a9416	KRAS_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	2.27593247495448	2.29904515170003	-0.0231126767455421	1.66236694427577	1.353654609493	0.0162418587365572	0.0139034746962028	0.0170742792019884	0.840103495890715	NA	NA	0.532303056822675	0.973918783458009	84.630557664662
a9417	gain_cnaOV4_(KRAS)	1006	Cytarabine	DNA synthesis	5	26	0.693147180559945	NA	-0.0111612012666045	-0.130568549337062	0.119407348070457	1.71129190110415	1.18368390385465	0.0940540448647524	0.0697761428038163	0.100877732375687	0.840208448704244	NA	NA	0.768448522684917	0.887425562762804	84.630557664662
a9418	loss_cnaOV16, loss_cnaOV17	329	QL-XI-92	DDR1	6	26	2.32630161961136	NA	4.69811493649527	4.49572661630449	0.202388320190782	1.19939518080895	0.983072616611944	0.197971554937817	0.168741982149935	0.205873215030943	0.840232117329928	NA	NA	0.193783458392277	0.712560844233259	84.630557664662
a9419	loss_cnaOV41	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.34885499747604	4.39432709129	-0.0454720938139666	0.815862663801902	1.01798856227877	0.0457734001372197	0.0557349855943494	0.0446685704524786	0.840242617967592	NA	NA	0.513836288614274	0.915853105423718	84.630557664662
a9420	loss_cnaOV34	1008	Methotrexate	Dihydrofolate reductase (DHFR)	5	26	-1.6094379124341	NA	0.743182166776232	0.53157615197392	0.211606014802312	1.41377543556682	1.18610804361012	0.173442025689942	0.149674417505687	0.178403658876011	0.840289496409138	NA	NA	0.433574144937677	0.765793306822524	84.630557664662
a9421	loss_cnaOV56	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-2.90264601139889	-3.35938897610691	0.456742964708019	2.3317437229493	1.79049448064278	0.249183227811971	0.195880430689145	0.25509319891567	0.840372628165428	NA	NA	0.141685494308658	0.770156607956192	84.630557664662
a9422	loss_cnaOV34	1054	PD-0332991	CDK4, CDK6	5	28	1.38629436111989	0.693147180559945	2.35093395225173	2.27223230074235	0.0787016515093826	1.4485263232104	1.8519438479294	0.0436029012338605	0.0543322204424661	0.0424967806650166	0.840464303678896	NA	NA	0.112411978111993	0.91805700131646	84.630557664662
a9423	loss_cnaOV70	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.505587815871273	-0.763872879805408	0.258285063934135	1.55445680819101	0.868267106232308	0.278331130290521	0.166157761716591	0.297471897852859	0.84072846763485	NA	NA	0.0429908014281632	0.802093277260335	84.630557664662
a9424	gain_cnaOV4_(KRAS)	306	TG101348	JAK2	8	24	2.32630161961136	NA	2.9125244704955	2.79457000082659	0.117954469668919	1.59194256258659	1.34626332727961	0.0838084337627063	0.0740946768062198	0.0876161946023364	0.840813071665092	NA	NA	0.629378811327909	0.854195810366972	84.630557664662
a9425	gain_cnaOV72_(ASXL1)	298	OSI-930	KIT, VEGFR, PDGFR	5	27	2.32630161961136	NA	4.2904951078089	4.48139408863202	-0.190898980823116	1.59259469163853	0.860294721541674	0.192875756812302	0.119866643927282	0.221899514251371	0.840819393007301	NA	NA	0.0321871907926576	0.805703456953669	84.630557664662
a9426	gain_cnaOV19	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	0.800718812987418	1.025225224314	-0.224506411326581	0.235524862997751	1.61413295387703	0.143860336811918	0.95321745852677	0.139087930016752	0.840846566393603	NA	NA	0.792152255992465	0.501311135344812	84.630557664662
a9427	loss_cnaOV54	154	CHIR-99021	GSK3B	6	13	0.940007258491471	NA	3.48736945683701	3.24209767286341	0.2452717839736	0.915610870296206	1.01099059634795	0.249285779913037	0.267877754546812	0.24260540588568	0.840941226398887	NA	NA	0.194221845196408	0.610272876904169	84.630557664662
a9428	loss_cnaOV38	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	5.8518916300888	5.81412259141638	0.0377690386724181	0.687151037422546	1.40892932222384	0.0291177822631246	0.0549646826032411	0.0268069079666849	0.840969186388541	NA	NA	0.573113567659769	0.922419147806602	84.630557664662
a9429	loss_cnaOV54	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.807449964298383	0.802014639771408	0.00543532452697515	0.474439419537783	1.19228624290774	0.00499884607240012	0.0114563088629323	0.00455874129162096	0.841046837543761	NA	NA	0.360805717685053	0.989541317132553	84.630557664662
a9430	ARID1A_mut	272	AR-42	HDAC	8	22	1.63315443905142	NA	0.467095646574268	0.232553094324296	0.234542552249973	1.71753320885861	1.90063345076008	0.126332329531327	0.136557797567034	0.123402306823642	0.841158491011336	NA	NA	0.488673951151533	0.752842426305768	84.630557664662
a9431	gain_cnaOV50	308	XL-880	MET	4	28	1.63315443905142	NA	0.285167982585073	0.248517031868908	0.0366509507161645	0.512599313771697	1.01779646269606	0.0374341332942828	0.0715001946578653	0.0360100983442986	0.841507208379725	NA	NA	0.37095360561622	0.912116475764485	84.630557664662
a9432	loss_cnaOV33_(ZFHX3)	1161	ZG-10	IRAK1	4	19	2.30258509299405	NA	1.6088290243229	1.57104889968409	0.0377801246388085	1.41527708567968	1.24645477416361	0.029702643212921	0.026694507401471	0.0303100645301468	0.841526174936019	NA	NA	0.167203757717199	0.962870438591331	84.630557664662
a9433	loss_cnaOV70	1495	AZD-2281	PARP1, PARP2	3	30	2.30258509299405	NA	3.56130378667388	3.56122960721095	7.41794629237624e-05	0.697289160884997	0.938251293205173	8.02285052800485e-05	0.000106382641642692	7.90614022714075e-05	0.841567297948651	NA	NA	0.145013267300947	0.999876128619243	84.630557664662
a9434	loss_cnaOV34	238	CAL-101	PI3Kdelta	5	27	2.99573227355399	2.32630161961136	4.51341800731095	4.36385245983909	0.149565547471857	0.813544737379836	1.01665507844768	0.150774845816435	0.183844281205185	0.147115330108051	0.841587098161676	NA	NA	0.513841347155742	0.728684011627197	84.630557664662
a9435	gain_cnaOV94	1262	UNC1215	LMBL3	7	26	0	NA	2.87098960510829	2.75602661592486	0.114962989183427	0.536650057455068	0.486296283331497	0.231574355875793	0.214223379996662	0.236405239200769	0.84160366901638	NA	NA	0.111570286500922	0.620578541083921	84.630557664662
a9436	gain_cnaOV72_(ASXL1)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-2.1060730524873	-1.96904022117454	-0.137032831312759	2.38825687659924	1.99401544573955	0.0668729519672113	0.0573777605983017	0.0687220510781626	0.841805465276488	NA	NA	0.280885449770559	0.908368549180831	84.630557664662
a9437	loss_cnaOV102	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	2.38851859243704	2.28368054243467	0.104838050002363	0.822938992359155	1.45734661606436	0.073689203158325	0.127394680499728	0.0719376220088832	0.841870540295991	NA	NA	0.532309767325271	0.859041252404617	84.630557664662
a9438	PIK3CA_mut	341	EX-527	SIRT1	6	25	2.99573227355399	NA	5.55898692955469	5.82475156273025	-0.265764633175558	0.560993646944527	0.558497347616611	0.475489466738991	0.4737391138439	0.475856571762981	0.842101418945534	NA	NA	0.112664490438664	0.329105577159891	84.630557664662
a9439	gain_cnaOV4_(KRAS)	1043	JNK Inhibitor VIII	JNK	7	26	2.30258509299405	NA	4.51466210681816	4.42248301900666	0.0921790878115001	0.985946089995198	1.02443841235774	0.0906291497572008	0.0934930304474852	0.0899801166176014	0.842106571060454	NA	NA	0.377500706548529	0.832106253128946	84.630557664662
a9440	loss_cnaOV70	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.64030192547269	3.54683627204978	0.0934656534229092	1.06502377047873	0.960025690409151	0.0966172920681993	0.0877592181636441	0.097357450281435	0.842206994162704	NA	NA	0.729936670731697	0.895517091659966	84.630557664662
a9441	gain_cnaOV4_(KRAS)	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.28501036484922	4.34228849207655	-0.0572781272273284	0.794871480622355	0.526168150774941	0.0967769953774401	0.0720596079035088	0.108858978147896	0.842281296460189	NA	NA	0.256743502691869	0.862219657288057	84.630557664662
a9442	loss_cnaOV52, loss_cnaOV53	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.7287682785547	1.52826988694604	0.200498391608658	1.25548035264736	1.04993392979385	0.185356319717801	0.159698549790826	0.190962865299557	0.842281789235958	NA	NA	0.457760314577785	0.780635842855056	84.630557664662
a9443	loss_cnaOV55	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.7287682785547	1.52826988694604	0.200498391608658	1.25548035264736	1.04993392979385	0.185356319717801	0.159698549790826	0.190962865299557	0.842281789235958	NA	NA	0.457760314577785	0.780635842855056	84.630557664662
a9444	gain_cnaOV51_(MYC)	1069	EHT 1864	Rac GTPases	8	25	2.30258509299405	NA	4.37932835873351	4.18132321669093	0.198005142042585	0.788995653128589	1.03201895621909	0.20155006905564	0.250958470122667	0.191861923513496	0.842459932145009	NA	NA	0.212009806548465	0.57649345244446	84.630557664662
a9445	gain_cnaOV95_(MECOM)	282	EKB-569	EGFR	9	23	0.916290731874155	2.99573227355399	1.60992908891106	1.7124392044136	-0.102510115502538	1.18412331443853	1.59384891803024	0.0685409269057483	0.0865704730686302	0.0643160806164901	0.84252362736333	NA	NA	0.329123652209526	0.8445534392731	84.630557664662
a9446	loss_cnaOV52, loss_cnaOV53	1241	CHIR-99021	GSK3B	8	24	2.30258509299405	NA	3.76311595998587	3.65423045201147	0.108885507974395	1.32682178766398	0.965029961605315	0.102669349456129	0.082064908028154	0.112831220072448	0.842533285383072	NA	NA	0.831920690271829	0.835016959314796	84.630557664662
a9447	NF1_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	1.04276475918745	1.18513031303056	-0.142365553843101	1.35226807774884	1.5195115451109	0.0946491612693511	0.105279090873831	0.0936916565729096	0.842825141152561	NA	NA	0.814075538419186	0.855129940484933	84.6509123530263
a9448	gain_cnaOV94	152	CP466722	ATM	7	25	2.77258872223978	NA	2.73397885426736	2.62253927762207	0.111439576645293	0.6549216032572	0.855383461965133	0.136030533311787	0.170157124289467	0.130280256283275	0.84296670139185	NA	NA	0.558134722788094	0.717372290748207	84.6557103574244
a9449	PIK3CA_mut	135	Gemcitabine	DNA replication	5	14	0.0237165266173161	NA	-1.50645599098707	-2.41022478231419	0.903768791327118	2.0782000439087	2.8180432197905	0.339440812823443	0.434880556362274	0.320707924200789	0.843051354838787	NA	NA	0.421548989964534	0.467911808128601	84.6557103574244
a9450	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	268	YM155	BIRC5 (Survivin)	5	25	1.63315443905142	NA	-4.35989554044993	-4.10941005272063	-0.250485487729295	0.771671129409811	2.5349861339665	0.105913756043201	0.324601346587725	0.0988113837677527	0.843356965538135	NA	NA	0.928478574395019	0.686832897237246	84.6736499336271
a9451	gain_cnaOV94	1175	AG-014699	PARP1, PARP2	7	26	1.6094379124341	NA	4.05232146948407	3.86046005709704	0.191861412387032	1.08389243825499	1.07956687531799	0.177582791233481	0.177011487132357	0.177720729279063	0.843619432922962	NA	NA	0.319016927990958	0.68664216759149	84.6736499336271
a9452	loss_cnaOV38	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	8	25	-1.38629436111989	0.693147180559945	-2.0197594976256	-2.38737302314924	0.367613525523636	1.18645070456431	1.72681281514398	0.22683490392225	0.309843067317856	0.212885567155688	0.84368688791877	NA	NA	0.126317414827924	0.507589025349496	84.6736499336271
a9453	loss_cnaOV38	1495	AZD-2281	PARP1, PARP2	8	25	2.30258509299405	NA	3.71481668963352	3.51209064237128	0.202726047262232	1.31020317840449	0.770175009561525	0.220295234160234	0.154728709717452	0.263220754692686	0.843704357512246	NA	NA	0.145020398721742	0.688101343370497	84.6736499336271
a9454	loss_cnaOV55	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	2.50909290034732	2.260763756284	0.248329144063324	0.779501379283982	1.31915464243158	0.200089331255733	0.318574348503949	0.188248698125022	0.843819280770707	NA	NA	0.393951315813835	0.643790378593958	84.6736499336271
a9455	gain_cnaOV51_(MYC)	287	KIN001-244	PDPK1 (PDK1)	8	24	2.99573227355399	NA	3.57220034450058	3.53509678209992	0.0371035624006635	0.562196703668977	0.99366960834377	0.0407083243112697	0.0659974741198592	0.0373399388379272	0.84392256581138	NA	NA	0.665053263213465	0.897241599635568	84.6736499336271
a9456	loss_cnaOV85	256	JW-7-24-1	LCK	7	25	2.32630161961136	NA	1.86870840138267	1.95912223159012	-0.0904138302074542	0.555422596513479	1.48636022893871	0.0668520439692891	0.162783852826665	0.060829016040083	0.843938140220959	NA	NA	0.839945331578341	0.805671598924896	84.6736499336271
a9457	loss_cnaOV43_(NF1)	223	ZSTK474	PI3K	5	27	1.63315443905142	2.32630161961136	0.865359040778674	0.738432054365216	0.126926986413457	1.11512163830061	1.04603135052602	0.120252410247189	0.113823444953403	0.121341474468838	0.844087359633399	NA	NA	0.773180543661964	0.822134621918498	84.6736499336271
a9458	loss_cnaOV55	222	BX-912	PDPK1 (PDK1)	7	25	2.32630161961136	NA	3.41154584747832	3.40946116874468	0.00208467873364349	1.02703035966322	1.27743257762098	0.00169288946274229	0.00202981218035958	0.00163192858093996	0.844091942643729	NA	NA	0.32944398516907	0.996495864250172	84.6736499336271
a9459	gain_cnaOV95_(MECOM)	238	CAL-101	PI3Kdelta	9	23	2.99573227355399	2.32630161961136	4.33596301921734	4.40727996866323	-0.0713169494458894	0.878334756595946	1.03155647896396	0.0718188393637132	0.0811956362996311	0.069135283331763	0.8441224090104	NA	NA	0.513850763537686	0.846678995346776	84.6736499336271
a9460	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	228	KIN001-102	AKT1	7	25	2.32630161961136	NA	2.69014416177957	2.81650072514766	-0.126356563368084	1.25390227368788	1.23363599539732	0.102088511375156	0.100770662929299	0.102426132051528	0.844968272886763	NA	NA	0.0965756168146005	0.81806626904336	84.7228532539538
a9461	gain_cnaOV96	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	1.99342910719518	1.88757437207074	0.105854735124439	1.46357548960597	1.38238033640467	0.0761301039346614	0.072326119066764	0.0765742482996743	0.844969967476698	NA	NA	0.035187867622552	0.898390223142102	84.7228532539538
a9462	loss_cnaOV55	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	7	24	2.30258509299405	NA	1.58829138943814	1.35673892718256	0.23155246225558	1.59424753072432	1.44354705211376	0.156879487752375	0.145242478218158	0.160405205993474	0.845064396224079	NA	NA	0.479009566488593	0.737800797792979	84.7228532539538
a9463	loss_cnaOV70	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.71433109809029	4.82184462995113	-0.107513531860837	0.857607494776254	0.744661102142774	0.142833687488173	0.125364496597464	0.14437914314507	0.845300439047027	NA	NA	0.766497222595153	0.851280530115247	84.7228532539538
a9464	loss_cnaOV57_(ZNRF3)	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	4.99519064578337	4.84076006074997	0.154430585033399	0.549699732723517	0.630927487698765	0.247770301751777	0.28093625635993	0.244767565281815	0.845330727855546	NA	NA	0.050876058772868	0.632073681473451	84.7228532539538
a9465	gain_cnaOV51_(MYC)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	-0.735162765891587	-0.510169700267788	-0.224993065623799	1.04317254223955	2.07836563976834	0.11925822127743	0.215681545011498	0.10825480431291	0.84533637057489	NA	NA	0.0445578820581689	0.760861044496074	84.7228532539538
a9466	loss_cnaOV55	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.21528029996089	3.25499330886639	-0.0397130089054989	1.40263231433346	0.991708016375525	0.0380896995339421	0.0283131997599605	0.04004506190304	0.845518962203593	NA	NA	0.569032161213017	0.96613293224176	84.7228532539538
a9467	loss_cnaOV20	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-1.9921230869028	-1.98938842931463	-0.00273465758816793	3.06252390139023	1.85325679990651	0.00133412344938104	0.000892942447543524	0.00147559560461663	0.84555408405662	NA	NA	0.28090055274401	0.9985386694035	84.7228532539538
a9468	loss_cnaOV39	254	AC220	FLT3	9	23	0.0237165266173161	NA	2.46831846387602	2.52745029501659	-0.0591318311405704	0.914510314613043	0.493982476727286	0.0932664646394829	0.0646595562627316	0.119704309214222	0.845626244833569	NA	NA	0.858899531955563	0.857908074150402	84.7228532539538
a9469	gain_cnaOV51_(MYC)	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	8	24	2.32630161961136	NA	5.2069136798978	5.12094760953479	0.0859660703630079	0.571666607350717	0.595931114448136	0.145616697173846	0.150377981252748	0.144255046059505	0.845667730343046	NA	NA	0.0123249471086357	0.721638167010044	84.7228532539538
a9470	gain_cnaOV95_(MECOM)	310	YM201636	FYV1	9	23	1.63315443905142	NA	2.30481604612295	2.37730373370923	-0.0724876875862841	0.315718992119057	1.0029008795752	0.0829216273918686	0.229595587835112	0.0722780177608258	0.845830350605323	NA	NA	0.652404965122367	0.759025014382759	84.7228532539538
a9471	gain_cnaOV19	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.29269489525621	4.4079789315739	-0.115284036317688	1.15494339311554	0.84339935579495	0.132986646533202	0.0998179105615744	0.136689737223035	0.846044586537204	NA	NA	0.870228599245834	0.880349898649734	84.7228532539538
a9472	gain_cnaOV96	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-4.63053830060111	-4.66037943676698	0.0298411361658717	1.24543529351354	2.22705633585301	0.0142941816328223	0.023960406711846	0.0133993629552446	0.846048483953521	NA	NA	0.35460756889592	0.972691223629659	84.7228532539538
a9473	loss_cnaOV81_(RB1)	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.41551892237955	2.2859275350259	0.129591387353647	1.90189717375345	1.20643434759883	0.102305031942207	0.0681379567423697	0.10741685829119	0.846104353176415	NA	NA	0.845417765042865	0.917798699193422	84.7228532539538
a9474	loss_cnaOV38	203	BMS-345541	IKBKB	8	24	2.77258872223978	NA	3.33447280304411	3.25676360052477	0.0777092025193427	1.36943155548038	0.930235615629702	0.0740589595798542	0.0567455906856794	0.0835371181383322	0.846337060771113	NA	NA	0.0936957124822009	0.884428329499147	84.7228532539538
a9475	gain_cnaOV94	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	1.6094379124341	NA	1.36669868501408	1.33208081705002	0.0346178679640512	1.4428092637343	1.34186747501725	0.0253914839427721	0.0239933779427314	0.0257982763637714	0.846392282611695	NA	NA	0.583058401524972	0.955968534344825	84.7228532539538
a9476	ARID1A_mut	184	BMS-754807	IGF1R	5	12	0.940007258491471	NA	1.08863474200741	0.6844013720154	0.404233369992007	1.65214081055326	0.75311035435063	0.377967562994739	0.244672468236311	0.536751842086354	0.846654700426732	NA	NA	0.360854385977224	0.623436264482052	84.7228532539538
a9477	TP53_mut	268	YM155	BIRC5 (Survivin)	20	10	1.63315443905142	NA	-4.08864503553792	-4.27618283095071	0.18753779541279	2.42853639608686	2.22557323905852	0.0792905132669526	0.077222559116253	0.0842649399810917	0.846660533561003	NA	NA	0.928480794335773	0.83508806113916	84.7228532539538
a9478	loss_cnaOV36	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.85037421108088	1.53670612790234	0.313668083178549	1.62924810277602	1.22289288041928	0.247524587884977	0.19252321524518	0.256496777600836	0.846796685578257	NA	NA	0.16723121285267	0.775086635533606	84.7228532539538
a9479	gain_cnaOV51_(MYC)	312	AV-951	VEGFR	8	24	-2.05572501506252	NA	0.771102255589497	0.59609541330422	0.175006842285277	0.457701590107745	0.65834889039601	0.283461668400441	0.382360136096707	0.265826896404438	0.846805868998248	NA	NA	0.0156253380922408	0.416649134893225	84.7228532539538
a9480	loss_cnaOV16, loss_cnaOV17	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	6	26	1.63315443905142	NA	2.68788238213161	2.90435616260239	-0.216473780470773	0.742345207368712	0.817210014645974	0.268839371768651	0.29160797203511	0.264893695122609	0.846830214865855	NA	NA	0.0201247348467467	0.545241243641766	84.7228532539538
a9481	loss_cnaOV84	1042	BIRB 0796	p38, JNK2	6	27	2.30258509299405	NA	4.32474557611675	4.41366589541797	-0.0889203193012182	0.96180581590599	0.84735378426968	0.102580265720584	0.0924514260890159	0.104938835409648	0.846923825448231	NA	NA	0.87022954647333	0.840435882812765	84.7228532539538
a9482	gain_cnaOV48_(SOX17)	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.06116431862739	3.01954022884911	0.0416240897782707	1.03836453052416	1.21384534576028	0.0346127397411861	0.0400862014780677	0.034291098057636	0.84696095248076	NA	NA	0.0903504113283658	0.95291245381283	84.7228532539538
a9483	PIK3R1_mut	230	GSK429286A	ROCK2	5	27	2.99573227355399	2.32630161961136	5.46156931075251	5.55303774099733	-0.0914684302448174	0.494805136548924	1.04333274352796	0.0925839165383463	0.184857479214494	0.0876694715202009	0.847033412074998	NA	NA	0.306888664293805	0.764743329128982	84.7228532539538
a9484	loss_cnaOV54	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	11	22	1.6094379124341	NA	1.07141266068602	1.21610449304953	-0.144691832363512	1.93122758943313	1.24893921654675	0.0962522240738102	0.0749222065567028	0.115851780812502	0.847070130108815	NA	NA	0.814082093227622	0.824409076011489	84.7228532539538
a9485	PTEN_mut	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	2.49873581953144	2.87988526865884	-0.381149449127401	2.39432119144715	1.82104788660102	0.204396290792593	0.159188938597261	0.209302265982042	0.847106514588012	NA	NA	0.349029427111669	0.811458116934891	84.7228532539538
a9486	loss_cnaOV84	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	1.37765336406207	1.105549893724	0.272103470338071	2.30508445326385	1.30403521366551	0.170377643149787	0.11804490284631	0.208662670675293	0.847158928386968	NA	NA	0.538677810104125	0.812598760501699	84.7228532539538
a9487	loss_cnaOV82	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.5899657596855	1.2809183882786	0.309047371406903	1.21482906950876	1.22506092496704	0.252411018250443	0.254395765761411	0.252271021880171	0.847223647676423	NA	NA	0.0993350753926081	0.709193732579032	84.7228532539538
a9488	loss_cnaOV44	1026	17-AAG	HSP90	3	30	0	NA	0.0198300437246982	-0.585898378491524	0.605728422216222	0.913092141533745	2.37480942538468	0.262378561069614	0.663381486559246	0.255064013028373	0.847270296481458	NA	NA	0.0626367441869748	0.412304260239873	84.7228532539538
a9489	loss_cnaOV33_(ZFHX3)	292	Masitinib	KIT	4	28	2.99573227355399	NA	4.2203903148016	3.98396757831837	0.23642273648323	0.360957265170802	1.10630276687564	0.223944593867256	0.654988164239766	0.213705274507197	0.847344793753081	NA	NA	0.1065864280635	0.406709027115043	84.7228532539538
a9490	gain_cnaOV51_(MYC)	163	JQ1	BRD4	5	14	0.940007258491471	NA	-0.137432156879123	0.169205130727152	-0.306637287606275	1.78315205971547	1.91413548069323	0.162746962517277	0.171963622471548	0.160196229942523	0.847380974838859	NA	NA	0.585800756927142	0.754957049221037	84.7228532539538
a9491	loss_cnaOV16, loss_cnaOV17	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	6	26	2.99573227355399	NA	4.02492942956313	4.03448077673233	-0.00955134716919481	1.17187947972135	1.56884479727254	0.00632561013790132	0.0081504517610172	0.00608814025823331	0.84754116568201	NA	NA	0.332448240324864	0.986944486391879	84.7299411170425
a9492	loss_cnaOV43_(NF1)	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.822203591770674	0.799241385636415	0.0229622061342591	0.107552097372509	1.16716253294322	0.0211189703410861	0.213498450473997	0.0196735291668038	0.847730659171053	NA	NA	0.360863513682533	0.943474541038499	84.7313532927136
a9493	loss_cnaOV38	228	KIN001-102	AKT1	8	24	2.32630161961136	NA	2.99595465801779	2.71982874987525	0.276125908142533	1.13804333139429	1.26012515628389	0.223997031713871	0.242632156900592	0.219125780296958	0.8478000260809	NA	NA	0.0965834271442074	0.572840990977306	84.7313532927136
a9494	gain_cnaOV94	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-1.38033779637685	-1.60825864293759	0.227920846560745	0.486395974824664	1.40161082858633	0.171741956106789	0.468591144577021	0.162613502915518	0.84795929377335	NA	NA	0.625565165779719	0.622892309392407	84.7313532927136
a9495	loss_cnaOV34	1243	piperlongumine	Increases ROS levels	5	27	2.30258509299405	NA	1.73393723272324	1.59235145214835	0.141585780574886	0.828360774779856	0.662927331069072	0.206005960599666	0.170922845317626	0.213576622865371	0.848043633552196	NA	NA	0.211588703179285	0.73261006347186	84.7313532927136
a9496	gain_cnaOV19	293	MP470	PDGFR	3	29	2.99573227355399	NA	3.79946223947291	4.0750820883769	-0.275619848903995	0.837000086558058	1.82828960325305	0.154888946895107	0.329294886978338	0.150752839382551	0.848089191074583	NA	NA	0.624182376236144	0.662972710526336	84.7313532927136
a9497	loss_cnaOV102	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.42932429369449	3.5686615443027	-0.139337250608213	1.38491808652834	0.929856028461214	0.144110203595328	0.100610463509433	0.149848198369802	0.848223714463401	NA	NA	0.729950302665816	0.879197269635549	84.7313532927136
a9498	gain_cnaOV51_(MYC)	231	FMK	RSK	5	15	2.99573227355399	2.32630161961136	5.29806144939212	5.22445339050163	0.0736080588904917	0.619795408531186	0.785474792002951	0.0979066130866088	0.11876186541125	0.0937115482761605	0.848265471425272	NA	NA	0.129946633272441	0.835229783645263	84.7313532927136
a9499	gain_cnaOV51_(MYC)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	2.40619741929147	2.39643388947054	0.00976352982093687	0.992360857148583	1.00056150442147	0.00977684589623521	0.00983868897146052	0.00975805063236187	0.848365480943017	NA	NA	0.414888180040269	0.985481535583252	84.7313532927136
a9500	loss_cnaOV83	1022	AZD7762	CHEK1, CHEK2	5	26	0.693147180559945	NA	-0.764290885404432	-0.825270500648142	0.0609796152437104	0.747356184523533	0.823135930230042	0.0749961248160179	0.0815937788520305	0.0740820719934659	0.848466937705291	NA	NA	0.0804391206673334	0.874870567318921	84.7313532927136
a9501	loss_cnaOV40	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.39046781690848	3.51852758525253	-0.128059768344055	0.848784652631681	1.1829801845807	0.114131913032374	0.150874274112995	0.10825182874001	0.848519644191585	NA	NA	0.72834047847135	0.7546323796479	84.7313532927136
a9502	loss_cnaOV34	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.07779991990888	3.96170556530604	0.116094354602843	0.975901820863962	0.729061134995101	0.151444649826113	0.118961100513231	0.159238161287562	0.848537601889037	NA	NA	0.527919546506502	0.810441257604839	84.7313532927136
a9503	loss_cnaOV33_(ZFHX3)	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.30654826825132	4.29855324354555	0.00799502470576385	1.07018221087861	0.772148094177609	0.00989369773273443	0.00747071351447714	0.010354263341515	0.848929182423783	NA	NA	0.227777745991424	0.989300592137871	84.7534746095053
a9504	gain_cnaOV26	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.49851197945401	3.36233442588806	0.136177553565948	2.49421837666124	1.60844692636041	0.0809581682712495	0.0545972858031123	0.084664001860534	0.848974287763923	NA	NA	0.63170772961079	0.934056165496807	84.7534746095053
a9505	loss_cnaOV35	1036	PLX4720	BRAF	5	28	2.30258509299405	NA	4.49885254570648	4.27379024159459	0.225062304111892	1.41419078738855	1.30313221493811	0.170761988153889	0.159145644363512	0.172708725585901	0.849027107416983	NA	NA	0.373692510834779	0.752930001894153	84.7534746095053
a9506	MLL2_mut	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.54906322192842	4.59251036239861	-0.0434471404701826	1.01684582755607	0.947374596642572	0.0456299054670215	0.0427273626864412	0.0458605715459927	0.849166513517441	NA	NA	0.943464326225451	0.949016072197994	84.7584734644227
a9507	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.86913423592182	3.0384349736237	-0.169300737701889	1.63184570899446	0.97909239062191	0.155468291928491	0.103748005567396	0.172915997839949	0.849585611442793	NA	NA	0.437126280900607	0.832011996642106	84.7913854143419
a9508	loss_cnaOV33_(ZFHX3)	309	Y-39983	ROCK	4	28	2.99573227355399	NA	4.92946220918903	4.96926493720776	-0.0398027280187225	1.72724005712748	1.18215274472276	0.0319078789679589	0.0230441205057028	0.0336696997882935	0.850534270726563	NA	NA	0.37528717164825	0.966895601213035	84.867915026164
a9509	loss_cnaOV44	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.87926545067887	4.78636089654826	0.0929045541306186	1.10718679131052	0.626218107023628	0.13884456947562	0.0839104610529649	0.14835814085956	0.850742758891169	NA	NA	0.763408996698357	0.898666402584422	84.867915026164
a9510	PIK3CA_mut	1262	UNC1215	LMBL3	7	26	0	NA	2.59361457249247	2.83070450932143	-0.237089936828961	0.509850729695346	0.483456315400656	0.485167774066685	0.465018333837888	0.490406122076359	0.850784700176013	NA	NA	0.11159673811296	0.297869648378806	84.867915026164
a9511	loss_cnaOV20	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.48612564353712	4.52045898571931	-0.0343333421821983	0.297647101284219	0.628877954993832	0.0568446752708371	0.115349156884326	0.0545946028312203	0.850786153246303	NA	NA	0.617062733930106	0.861594879524253	84.867915026164
a9512	gain_cnaOV96	326	GSK690693	AKT	5	27	2.32630161961136	NA	4.20642925479615	4.14183890685217	0.0645903479439793	1.31032718677836	1.49279988197464	0.0439455990751901	0.0492932975791983	0.0432679213897985	0.850857854324365	NA	NA	0.0953575178864443	0.924335257800568	84.867915026164
a9513	gain_cnaOV51_(MYC)	222	BX-912	PDPK1 (PDK1)	8	24	2.32630161961136	NA	3.42173067477405	3.40597936469887	0.0157513100751889	1.11699308295848	1.26418188425737	0.0127912544689232	0.014101528752058	0.012459686593628	0.850889085671742	NA	NA	0.329471837278196	0.97385283050155	84.867915026164
a9514	loss_cnaOV20	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-2.27482957224692	-2.09656625622459	-0.178263316022331	1.67810778720294	1.2367448600562	0.136901468287486	0.106228763957683	0.144139120185412	0.851133424158333	NA	NA	0.609518932644274	0.829913782017061	84.8701985010518
a9515	gain_cnaOV94	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.6094379124341	NA	1.04659913268694	1.20052477637798	-0.153925643691037	1.5629979845289	1.48886955675643	0.102378059622628	0.0984810250650656	0.103384237385021	0.851172028187363	NA	NA	0.814088247966675	0.820447065486553	84.8701985010518
a9516	gain_cnaOV4_(KRAS)	295	NVP-BHG712	EPHB4	8	24	2.32630161961136	NA	3.31191135421064	3.23086922624913	0.0810421279615059	1.35001479326001	1.00502716450297	0.0739916803976838	0.0600305480844443	0.0806367537354921	0.851205173808468	NA	NA	0.0638016893498672	0.879228978851052	84.8701985010518
a9517	loss_cnaOV44	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.79125660643496	1.46734057843611	0.32391602799885	0.835032552775566	1.76214114534229	0.188763495153271	0.387908264081663	0.183819570217192	0.851269769003835	NA	NA	0.31884029040613	0.606533722422541	84.8701985010518
a9518	gain_cnaOV51_(MYC)	1262	UNC1215	LMBL3	8	25	0	NA	2.86636393203902	2.75290831173969	0.113455620299333	0.41373133113	0.517877238673679	0.22861465486027	0.274225352934859	0.219078213574131	0.851428930966493	NA	NA	0.111598532143549	0.536453426656255	84.8727030951058
a9519	loss_cnaOV70	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.783871644519233	-0.818816875368434	0.0349452308492008	1.11518483397088	0.786412256906098	0.0429638278733632	0.0313358196638758	0.0444362744124592	0.851604985119912	NA	NA	0.0804470057255187	0.962206467511843	84.8727030951058
a9520	gain_cnaOV95_(MECOM)	303	PIK-93	PI4K, PI3K	9	23	2.99573227355399	NA	2.82757384120419	2.93574648789975	-0.108172646695559	0.779020253603703	1.39066214697787	0.0860560056442558	0.138857296963922	0.0777849939545961	0.851638806184934	NA	NA	0.234211037208804	0.783303110682394	84.8727030951058
a9521	loss_cnaOV59	1241	CHIR-99021	GSK3B	4	28	2.30258509299405	NA	3.79286004285802	3.66553636988322	0.127323672974801	1.04379483442668	1.06264120894939	0.120029295901339	0.121981512817828	0.11981812102006	0.851731693510652	NA	NA	0.831933831103758	0.831202319109781	84.8727030951058
a9522	loss_cnaOV35	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	1.09708354620775	0.986972970852943	0.110110575354807	1.23904928133357	1.60537271955467	0.0705157702987726	0.0888669861753169	0.0685887918821438	0.851894411428538	NA	NA	0.792171707726246	0.867285510244456	84.8727030951058
a9523	SMAD4_mut	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.43191080447307	3.56839397422216	-0.136483169749086	1.28216195477493	0.940363919606798	0.141152971343016	0.106447683337356	0.145138671213752	0.851977746656893	NA	NA	0.729958526147583	0.872600126616035	84.8727030951058
a9524	TP53_mut	165	DMOG	Prolyl-4-Hydroxylase	12	7	8.29404964010203	NA	6.62220451170731	6.82696277365428	-0.204758261946973	1.53620857204327	1.5235706607333	0.133675155848768	0.133288061057119	0.134393676134734	0.852033625686953	NA	NA	0.341886632148555	0.78267197469022	84.8727030951058
a9525	gain_cnaOV49	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	2.77116654344664	2.85170277997796	-0.0805362365313189	1.99731442243525	1.85855532966967	0.0431106949212152	0.0403222625474882	0.0433327086074069	0.852097718902908	NA	NA	0.349049537377574	0.95187669961343	84.8727030951058
a9526	gain_cnaOV50	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	0.913123497934609	0.665152720276747	0.247970777657862	2.97033088996261	2.24553530368061	0.106507927040784	0.0834825434754792	0.110428358552822	0.852099940003904	NA	NA	0.946148121000372	0.881268647037328	84.8727030951058
a9527	MLL2_mut	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-3.43730046102578	-2.18435000588861	-1.25295045513717	1.88754448244736	1.56283024572708	0.790112559504447	0.663799167006974	0.801718842185739	0.852676439328066	NA	NA	0.126344558461804	0.369356043788777	84.9212101522721
a9528	loss_cnaOV70	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	6.02657375583238	5.93928730757169	0.0872864482606897	0.558928385843719	0.716937853661837	0.123319221795444	0.156167499220724	0.121748974217032	0.853172338131525	NA	NA	0.909201007791177	0.819880224902516	84.9531343331602
a9529	gain_cnaOV4_(KRAS)	276	CAY10603	HDAC6	7	24	2.99573227355399	NA	1.55356218699463	1.39808177354517	0.155480413449465	2.35672002060239	1.6295402386836	0.0861769207014737	0.0659732221435973	0.0954136693028623	0.853176052853562	NA	NA	0.616730680607761	0.874292382764226	84.9531343331602
a9530	SMARCA4_mut	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.34684055366172	4.42212772384719	-0.0752871701854705	1.31237860314301	0.92750841074096	0.0785887636538363	0.0573669595078473	0.0811714150660107	0.853304417961328	NA	NA	0.787647296019005	0.93088984695083	84.9570003812202
a9531	loss_cnaOV57_(ZNRF3)	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	4	29	1.6094379124341	NA	2.61359865931281	2.30670999250897	0.306888666803837	2.1324008120661	1.48833451426253	0.196432476434362	0.143916971456454	0.206196029093567	0.853553194499467	NA	NA	0.244714816218712	0.796569534260618	84.9636969766107
a9532	loss_cnaOV20	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.68419785309937	2.8970209353687	-0.212823082269329	0.914169039818694	0.788028975733773	0.26405206967864	0.232804955100578	0.270070122829125	0.853634831901923	NA	NA	0.0201312630681894	0.645529134120039	84.9636969766107
a9533	PIK3CA_mut	158	PF-562271	FAK	5	13	0.940007258491471	NA	2.30663120054087	2.28282776854096	0.0238034319999127	1.00135959952946	1.52684777301861	0.0168352371768849	0.0237711128061268	0.0155899182751224	0.853640315738572	NA	NA	0.749618952088985	0.969864779736256	84.9636969766107
a9534	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-1.90316803597934	-2.04805275091506	0.144884714935726	1.55215246536696	1.57546918802951	0.0921029742423879	0.0933443834729676	0.0919628997104905	0.853890773713646	NA	NA	0.0389105337159724	0.870448652815849	84.9797110485991
a9535	ARID1A_mut	1052	RO-3306	CDK1	9	24	1.6094379124341	NA	3.39890564857435	3.51287066466182	-0.113965016087466	1.03389638216377	0.864128059935301	0.125102503814321	0.110228663194427	0.131884406225623	0.854062604340642	NA	NA	0.795327862965353	0.773328530989633	84.9807100947413
a9536	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	291	KIN001-266	MAP3K8 (COT)	5	27	2.99573227355399	NA	3.22186357128618	3.31736297390832	-0.0954994026221372	0.965436725237099	1.13688391727057	0.0856076333572107	0.0989183445436922	0.0840010146782729	0.854196533951137	NA	NA	0.951207022623868	0.849848368876862	84.9807100947413
a9537	gain_cnaOV51_(MYC)	345	KIN001-270	CDK9	8	24	2.99573227355399	NA	5.28467455647247	5.15950761782833	0.125166938644134	0.785149595097427	0.772790258992569	0.161361705580565	0.159417949682063	0.161967541888151	0.854288682517917	NA	NA	0.336344550037507	0.701984006047695	84.9807100947413
a9538	gain_cnaOV51_(MYC)	1003	Camptothecin	TOP1	8	23	-2.30258509299405	NA	-3.62467409088483	-3.71429618944422	0.0896220985593907	1.51340175599971	1.81010415204888	0.0514148673074645	0.0592189735502117	0.0495121225250748	0.85429573226484	NA	NA	0.247930018816078	0.893008386611328	84.9807100947413
a9539	loss_cnaOV55	223	ZSTK474	PI3K	7	25	1.63315443905142	2.32630161961136	0.714106215363105	0.770628686568499	-0.0565224712053943	1.21168146476834	1.01374242660506	0.0535097777507076	0.0466479622317248	0.0557562450993431	0.854383212242355	NA	NA	0.773199846043354	0.912766030537544	84.9807100947413
a9540	gain_cnaOV4_(KRAS)	274	PXD101, Belinostat	HDAC	7	23	2.99573227355399	NA	0.992435214258638	0.812861155690053	0.179574058568585	2.62023042145591	1.92421883467656	0.0857998712481879	0.0685336896702414	0.0933230957583727	0.854674547597569	NA	NA	0.418809446154564	0.870674430727487	84.9807100947413
a9541	gain_cnaOV51_(MYC)	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	5.06029458324342	4.65367238490022	0.406622198343206	1.31339226546389	1.65338349528314	0.257358860711877	0.309596918632368	0.245933384180524	0.854706358809727	NA	NA	0.125262906439933	0.593699071159205	84.9807100947413
a9542	loss_cnaOV55	346	THZ-2-102-1	CDK7	7	25	0.916290731874155	2.99573227355399	-1.04182597593194	-1.06434404674297	0.0225180708110284	1.59534384380133	2.07642396326232	0.0113182523869978	0.0141148699062724	0.0108446402129022	0.854910670773558	NA	NA	0.446181444152502	0.975955776298019	84.9807100947413
a9543	loss_cnaOV57_(ZNRF3)	1264	SGC0946	Q8TEK3 (DOT1L)	4	29	-0.693147180559945	NA	2.24384071657632	2.09758407708017	0.146256639496154	0.631949055044916	0.553382082590536	0.260490628550956	0.231437389341074	0.264295943250431	0.854926692987545	NA	NA	0.0434048978513006	0.684513944721764	84.9807100947413
a9544	gain_cnaOV48_(SOX17)	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.68619243521188	8.75637357527486	-0.0701811400629779	1.25155792211894	1.24498307595316	0.0563505859205697	0.0560750236346698	0.0563711599125533	0.85495105759599	NA	NA	0.532356788523786	0.933447029935658	84.9807100947413
a9545	loss_cnaOV58	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	1.63222135522359	1.56245213417619	0.0697692210474057	1.37800840467269	1.24533857510336	0.0548639665726717	0.0506304757001666	0.0560242992887417	0.854969225431117	NA	NA	0.167271863352851	0.921947245412031	84.9807100947413
a9546	loss_cnaOV52, loss_cnaOV53	1371	PLX4720 (rescreen)	BRAF	9	24	2.30258509299405	NA	4.55070008627941	4.51986746024425	0.0308326260351519	1.1557653930214	0.934207089312162	0.0309529596608723	0.0266772359004014	0.0330040591512245	0.85501994089373	NA	NA	0.32815676545897	0.94398750167597	84.9807100947413
a9547	KRAS_mut	255	CP724714	ERBB2	7	25	2.32630161961136	NA	4.49563826033353	4.39251031320876	0.103127947124777	1.26903932019329	0.861848071986891	0.107734128302074	0.0812645798154387	0.119659079687941	0.855147519057258	NA	NA	0.787650430595735	0.844951625442281	84.9807100947413
a9548	loss_cnaOV55	1005	Cisplatin	DNA crosslinker	7	24	1.79175946922805	2.30258509299405	3.25309523081632	2.9566230311643	0.296472199652025	0.953652539095605	1.25126706718325	0.247931140509497	0.310880732235227	0.236937587048798	0.855154704830437	NA	NA	0.0903722392765785	0.514172155036175	84.9807100947413
a9549	TP53_mut	173	FH535	unknown 	11	7	3.46573590279973	NA	2.41428825027473	2.62652917549937	-0.212240925224639	1.35923422344714	1.6053696821258	0.145728043665504	0.156147425928091	0.132206885172762	0.855271897596943	NA	NA	0.125035650991893	0.777165267370927	84.9834554311927
a9550	loss_cnaOV82	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	0.849639543106468	0.843294245817341	0.00634529728912692	1.88202021292654	1.31254993367235	0.00467761707322337	0.00337153514374852	0.00483432829970404	0.855483146511696	NA	NA	0.165584415934815	0.995925683099019	84.9955450332389
a9551	gain_cnaOV18_(CCNE1)	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	1.77685138875883	1.52804070381837	0.248810684940453	1.24326064230704	1.03157907580076	0.234080031513773	0.200127532774423	0.241194001290995	0.855868703083619	NA	NA	0.290744552757714	0.727121834149481	85.0106027055409
a9552	gain_cnaOV96	135	Gemcitabine	DNA replication	4	15	0.0237165266173161	NA	-2.12940930097231	-2.18385264689632	0.0544433459240152	1.11956928010861	2.92468594004123	0.0201981848550594	0.0486288315438001	0.0186151084390441	0.855870404263056	NA	NA	0.421640045706404	0.954635192654576	85.0106027055409
a9553	loss_cnaOV84	197	Bryostatin 1	PRKC	5	14	-4.8283137373023	NA	-2.35443514976783	-2.31610562188865	-0.0383295278791791	0.958666116047314	0.695831023616235	0.0500494337676945	0.0399821452303081	0.0550845342881961	0.85590348828279	NA	NA	0.677476054683855	0.937490718244742	85.0106027055409
a9554	loss_cnaOV20	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.37769522879661	3.51113310078604	-0.133437871989433	0.56062634341285	1.1877167701675	0.118901962850675	0.238015700755553	0.112348225891106	0.856045529060686	NA	NA	0.728357393463128	0.70321138219284	85.0158111884629
a9555	gain_cnaOV95_(MECOM)	1072	BMS-708163	g-secretase	8	25	1.6094379124341	NA	3.7905022281718	3.8576557889429	-0.0671535607710991	0.910947049737575	0.85924435005099	0.0770827959913571	0.0737184019537082	0.0781542069693144	0.856147636862195	NA	NA	0.92416725852903	0.857309806480639	85.0170531623253
a9556	gain_cnaOV19	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	3.74685383841011	3.85082836779055	-0.103974529380435	0.372234804537867	0.895365882552089	0.119353524094487	0.279325114451672	0.116125185699586	0.856240285278365	NA	NA	0.924167313335352	0.716424878269686	85.0173556399867
a9557	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.72310700863209	2.49484456779473	0.228262440837361	0.927534672231531	1.05780526622436	0.218511362692105	0.246095857838059	0.21578871662466	0.856369483841222	NA	NA	0.198374764086703	0.674945973126019	85.0212867923667
a9558	gain_cnaOV19	1268	XAV 939	TNKS1 (tankyrase-1)	3	29	1.6094379124341	NA	2.66376276368337	2.87573506920296	-0.211972305519583	1.17636299978891	1.07211546926226	0.196383648909507	0.180192938368191	0.197714063080765	0.856536684810348	NA	NA	0.309553544414149	0.788950388628805	85.0289896473358
a9559	gain_cnaOV72_(ASXL1)	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	2.00764060113816	2.1774743402472	-0.169833739109033	1.3984726420223	1.3724435246063	0.123303682363383	0.121442303557287	0.123745521082736	0.856747262008738	NA	NA	0.89344189867407	0.838547352008647	85.0409964285027
a9560	MLL2_mut	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	2.93845737514291	3.30113046300272	-0.362673087859817	1.12549317965477	1.02286671434998	0.350697060533365	0.322234816181704	0.354565343433129	0.857049484092347	NA	NA	0.569092454490531	0.642305119213638	85.0538640577734
a9561	loss_cnaOV41	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.54319307520356	4.50699394097203	0.0361991342315324	1.72297428546924	0.788295032145654	0.0389389733340655	0.0210096775888178	0.0459207945697721	0.857145819757418	NA	NA	0.530869900850509	0.969447263812026	85.0538640577734
a9562	loss_cnaOV42	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.54319307520356	4.50699394097203	0.0361991342315324	1.72297428546924	0.788295032145654	0.0389389733340655	0.0210096775888178	0.0459207945697721	0.857145819757418	NA	NA	0.530869900850509	0.969447263812026	85.0538640577734
a9563	loss_cnaOV52, loss_cnaOV53	207	AS601245	JNK 	4	14	2.07944154167984	NA	1.85214044604966	2.03385058284592	-0.181710136796263	0.832184399377957	1.03451731283484	0.181763926764845	0.218353212259312	0.175647265194944	0.857422267575139	NA	NA	0.484239948999357	0.728603450586537	85.0723988187118
a9564	gain_cnaOV94	299	OSI-027	MTORC1/2	7	25	2.99573227355399	NA	1.3784873249306	1.5737709156683	-0.195283590737696	1.14860978402573	2.08330412373999	0.101032976261435	0.170017349193433	0.093737437809665	0.8577885198567	NA	NA	0.783820013146834	0.749217924889244	85.0730312630104
a9565	gain_cnaOV19	1067	CCT007093	PPM1D	3	30	1.88706964903238	NA	4.5124329299473	4.48745750685094	0.0249754230963619	1.36449702807042	0.635698990513796	0.0353857206220712	0.0183037577822214	0.0392881276658562	0.857828406520106	NA	NA	0.0830838607358966	0.977720842924606	85.0730312630104
a9566	gain_cnaOV26	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.72572318878662	6.69237649935673	0.0333466894298864	2.5396440294751	1.34585471844286	0.0217205318163293	0.0131304580653292	0.0247773321837205	0.857864036169183	NA	NA	0.341927713251376	0.984152304356984	85.0730312630104
a9567	loss_cnaOV81_(RB1)	277	ABT-869	VEGFR and PDGFR family	4	28	0.0237165266173161	NA	2.72633405377742	2.7145646967717	0.0117693570057242	0.462430310327545	0.585212869982269	0.0204999108587035	0.0254510933709944	0.0201112408995394	0.857879222230902	NA	NA	0.137784418487409	0.96533982840369	85.0730312630104
a9568	gain_cnaOV18_(CCNE1)	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	1.86724134368986	1.85899926533631	0.00824207835354152	0.894695420338699	1.81335008009695	0.00488285212979372	0.00921216110664942	0.00454522182120556	0.858050452444264	NA	NA	0.350825683145995	0.990083998721007	85.0730312630104
a9569	PIK3CA_mut	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-1.94229258358472	-1.06266787418285	-0.879624709401876	1.77045162172639	1.24971112805793	0.672359038310835	0.496836343115742	0.703862428406818	0.858322402329901	NA	NA	0.0510348285947043	0.483511849388284	85.0730312630104
a9570	loss_cnaOV39	302	PI-103	PI3Ka, PRKDC (DNAPK)	9	23	2.32630161961136	NA	1.55034764812095	1.18797577991016	0.362371868210795	2.13319529508601	2.41136675372655	0.154831805385814	0.169872804916432	0.150276546548044	0.858381118075142	NA	NA	0.366210326787408	0.682698627044187	85.0730312630104
a9571	gain_cnaOV48_(SOX17)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.04416431458286	-2.13151700305916	0.0873526884762965	0.561870192567681	1.33963856670286	0.0670118991468658	0.155467739046816	0.0652061613090839	0.858384287235303	NA	NA	0.609539350125546	0.838569900190637	85.0730312630104
a9572	PIK3CA_mut	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	-0.506256756526257	-0.572915849895581	0.0666590933693245	1.55981086110576	1.49131006483331	0.0442122061542239	0.0427353694165646	0.0446983460657964	0.858626957317097	NA	NA	0.910145529274594	0.936259248810055	85.0730312630104
a9573	loss_cnaOV81_(RB1)	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.40246968674358	4.16768268211124	0.234787004632342	0.69728297223758	1.00496756722027	0.239930562907909	0.336716962811972	0.233626449539819	0.858639709634764	NA	NA	0.0493568877073279	0.580008282543919	85.0730312630104
a9574	loss_cnaOV81_(RB1)	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.28867349506875	2.4085133492919	-0.119839854223147	0.520460516557729	0.985698601782171	0.126215097431998	0.230257340202778	0.121578598170346	0.858702535340467	NA	NA	0.736273841424625	0.719683503195356	85.0730312630104
a9575	loss_cnaOV33_(ZFHX3)	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.56260522224734	1.27378963036237	0.288815591884968	0.993412053539699	1.24692829065335	0.235971642214512	0.290730911564711	0.231621653025163	0.858826409415688	NA	NA	0.0993660951180195	0.624301944312248	85.0730312630104
a9576	loss_cnaOV43_(NF1)	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	0.153009476330057	0.111355680160234	0.0416537961698224	1.5423232393759	1.65150980273173	0.0254470264781409	0.0270071766452002	0.0252216463389582	0.858858308731449	NA	NA	0.464531935855205	0.958206961266194	85.0730312630104
a9577	loss_cnaOV57_(ZNRF3)	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.40699116220706	3.21222093003821	0.194770232168853	1.35800634455619	0.968331988182746	0.187348307977195	0.143423654057012	0.201139933974892	0.859193708347911	NA	NA	0.569103127456737	0.800581230404399	85.0730312630104
a9578	loss_cnaOV58	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.40699116220706	3.21222093003821	0.194770232168853	1.35800634455619	0.968331988182746	0.187348307977195	0.143423654057012	0.201139933974892	0.859193708347911	NA	NA	0.569103127456737	0.800581230404399	85.0730312630104
a9579	PIK3R1_mut	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	2.89857421440512	2.99021420395715	-0.091639989552033	0.186869459602762	0.644916178161574	0.150433035216933	0.49039575405653	0.142095969453373	0.859204991307307	NA	NA	0.851094357088752	0.64476081277737	85.0730312630104
a9580	loss_cnaOV70	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.56601647785764	2.50510943195492	0.0609070459027157	0.538657570335772	0.640626726841171	0.0960165642670152	0.113071920375591	0.09507415683863	0.859265611810399	NA	NA	0.85891536883626	0.868059602073262	85.0730312630104
a9581	loss_cnaOV87, loss_cnaOV88	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.37357221942847	4.52646043031334	-0.152888210884865	2.06889660792876	0.780387304627543	0.164653183142981	0.0738984298678542	0.195913247150829	0.859373813028849	NA	NA	0.530877416501992	0.910227759382699	85.0730312630104
a9582	gain_cnaOV49	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.5162971916411	4.48661712963836	0.0296800620027424	0.400744048539752	0.698553246750426	0.0435063094613923	0.0740623899740792	0.0424879021618037	0.859465103687121	NA	NA	0.054766857537814	0.917396333704468	85.0730312630104
a9583	loss_cnaOV84	152	CP466722	ATM	6	26	2.77258872223978	NA	2.73331568723249	2.62697845373186	0.106337233500628	0.601555017080918	0.856442013622171	0.1297610644428	0.176770587030652	0.12416162660084	0.859519942596592	NA	NA	0.558189077363485	0.727991371748387	85.0730312630104
a9584	loss_cnaOV70	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.06924006682619	5.06125608598514	0.00798398084105045	0.572438613645661	0.62609106801242	0.0128224158018353	0.0139473135646865	0.0127521078784853	0.859555162527845	NA	NA	0.112560056854613	0.983497796635345	85.0730312630104
a9585	gain_cnaOV95_(MECOM)	293	MP470	PDGFR	9	23	2.99573227355399	NA	3.95168701583113	4.08741670168995	-0.135729685858821	1.93648018163534	1.71997433013664	0.0762404010813706	0.0700909243203295	0.0789137857935577	0.859578735178295	NA	NA	0.624215058231627	0.856949060694672	85.0730312630104
a9586	loss_cnaOV44	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-2.04559198751375	-2.13137423576607	0.0857822482523134	0.664362004766116	1.33640920344547	0.0658066856042605	0.129119738390988	0.0641886093205235	0.859930319199951	NA	NA	0.609543565873064	0.859734746657499	85.0730312630104
a9587	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1052	RO-3306	CDK1	8	25	1.6094379124341	NA	3.53556322523011	3.46458163948848	0.0709815857416283	1.20121461859013	0.808292767737507	0.0778360526438907	0.0590915100791396	0.0878166780340159	0.859986741480804	NA	NA	0.795337074039097	0.879276683329885	85.0730312630104
a9588	loss_cnaOV38	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	4.83513316181382	4.74082357717099	0.0943095846428337	2.30749636787489	1.38989324700052	0.0592858191631836	0.0408709569192905	0.0678538332683896	0.860156540839067	NA	NA	0.125291103372821	0.941926508383188	85.0730312630104
a9589	gain_cnaOV50	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	0.8456172312308	1.02682925068375	-0.181212019452951	0.917758787040455	1.61655906820659	0.116100382057464	0.19745059596467	0.112097369664313	0.860275820882507	NA	NA	0.792185487610733	0.753336111713845	85.0730312630104
a9590	gain_cnaOV18_(CCNE1)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-4.2098916037014	-3.92181099054501	-0.288080613156395	1.68173300723756	1.87039924470804	0.156692217835774	0.171299850759069	0.154020920384494	0.860318490973293	NA	NA	0.594280705842638	0.777935799619939	85.0730312630104
a9591	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	2.87168313437709	2.78468464473846	0.0869984896386362	1.52048825180946	0.85826933496226	0.0897375617432828	0.0572174691485473	0.101365021555223	0.86063127383412	NA	NA	0.96638265062034	0.906362558306158	85.0730312630104
a9592	loss_cnaOV54	298	OSI-930	KIT, VEGFR, PDGFR	10	22	2.32630161961136	NA	4.54970323224294	4.40695834589452	0.142744886348422	1.21929454844824	0.873464819474205	0.144189526162884	0.117071700624012	0.163423738616455	0.860666223030851	NA	NA	0.0322138146184584	0.744024434307311	85.0730312630104
a9593	loss_cnaOV40	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-2.9327735756825	-2.69779619759694	-0.234977378085562	1.64945029008412	1.13227576429827	0.189601144033241	0.142457993125442	0.207526633965525	0.860667876644914	NA	NA	0.383805035924767	0.802265227133515	85.0730312630104
a9594	ARID1A_mut	1006	Cytarabine	DNA synthesis	9	22	0.693147180559945	NA	-0.23184504805643	-0.0619992207540345	-0.169845827302396	1.32995771830087	1.24340180224882	0.133961585823188	0.127707689474059	0.136597700755469	0.860687331375149	NA	NA	0.768488747694962	0.747139536424775	85.0730312630104
a9595	loss_cnaOV33_(ZFHX3)	1259	BMN-673	PARP1	4	29	2.30258509299405	NA	2.00573161436158	1.88587747453055	0.119854139831033	1.24574095363879	1.40492440030204	0.0862063820440017	0.0962111259816419	0.0853100279312295	0.860742727481626	NA	NA	0.0352093450695955	0.867493084520379	85.0730312630104
a9596	PIK3R1_mut	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	0.0752798577779322	-0.0890431273625745	0.164322985140507	0.492288335573555	1.02434955987986	0.169333215534997	0.333794187808771	0.160416904127707	0.860777193690135	NA	NA	0.55124178094426	0.588552999620107	85.0730312630104
a9597	loss_cnaOV38	1058	GDC0941	PI3K (class 1)	8	25	1.38629436111989	0.693147180559945	1.05384184380516	0.776680450135934	0.277161393669228	0.69196333052155	1.48923475101598	0.205156133689286	0.400543470215863	0.186109942358076	0.860799776271595	NA	NA	0.165601217993111	0.478437979459995	85.0730312630104
a9598	loss_cnaOV38	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	4	15	2.77258872223978	NA	4.91086620759251	5.06398883871184	-0.153122631119328	1.11632342484537	1.21702270046731	0.127616389891701	0.137166906750648	0.12581739934722	0.860813911902256	NA	NA	0.802819452365782	0.820385919363632	85.0730312630104
a9599	loss_cnaOV34	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.33445794464506	4.32837333232909	0.00608461231596813	0.874709320294997	0.533505394419576	0.0102716408434134	0.0069561535184238	0.0114049686837522	0.860974095132775	NA	NA	0.256818861099991	0.988642346054803	85.0730312630104
a9600	loss_cnaOV85	190	Bleomycin	DNA damage	6	13	4.15888308335967	NA	1.71068523631036	1.64643047545684	0.0642547608535189	3.27864468249961	1.83386011579607	0.0273102432904407	0.0195979641211172	0.0350379837044584	0.861043554192243	NA	NA	0.617055491937328	0.965556269455195	85.0730312630104
a9601	loss_cnaOV84	1264	SGC0946	Q8TEK3 (DOT1L)	6	27	-0.693147180559945	NA	2.23235006398828	2.0893037302852	0.143046333703079	0.714631244509008	0.52600891067465	0.25510279420985	0.20016803743497	0.27194659786202	0.861101080723483	NA	NA	0.0434142339144167	0.658879820413605	85.0730312630104
a9602	gain_cnaOV19	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.96647586126755	4.83779326690301	0.12868259436454	0.613753250388447	0.926812484776484	0.141613082166555	0.209665031155593	0.138844260816765	0.861249462453596	NA	NA	0.667239959423405	0.765611840113871	85.0730312630104
a9603	loss_cnaOV16, loss_cnaOV17	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-0.869289039608885	-1.24226731978819	0.372978280179304	1.27888761118006	1.34566983793399	0.279105611135939	0.291642734606794	0.277169235473047	0.861397906023453	NA	NA	0.0510423016138243	0.624116980359646	85.0730312630104
a9604	loss_cnaOV41	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-0.869289039608885	-1.24226731978819	0.372978280179304	1.27888761118006	1.34566983793399	0.279105611135939	0.291642734606794	0.277169235473047	0.861397906023453	NA	NA	0.0510423016138243	0.624116980359646	85.0730312630104
a9605	loss_cnaOV42	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-0.869289039608885	-1.24226731978819	0.372978280179304	1.27888761118006	1.34566983793399	0.279105611135939	0.291642734606794	0.277169235473047	0.861397906023453	NA	NA	0.0510423016138243	0.624116980359646	85.0730312630104
a9606	loss_cnaOV82	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.04181166076009	2.76269283720235	0.279118823557741	0.253336812603582	1.27762833139531	0.225817305812608	1.10176969817056	0.218466369834577	0.861434588696209	NA	NA	0.0966189297803439	0.330142107640151	85.0730312630104
a9607	gain_cnaOV95_(MECOM)	281	CH5424802	ALK	9	23	1.63315443905142	NA	3.89071303840365	3.94204189690049	-0.051328858496841	0.559198712011622	0.789594263819364	0.0698115461108596	0.0917900155960555	0.0650066253629516	0.861435687264917	NA	NA	0.956044449058666	0.838498296795367	85.0730312630104
a9608	loss_cnaOV42	1026	17-AAG	HSP90	4	29	0	NA	-0.396032003969231	-0.549425283023955	0.153393279054723	1.11695559899929	2.40827831935333	0.0662603325935843	0.137331581660141	0.063694166003169	0.861482024174636	NA	NA	0.062664666941616	0.835778245537437	85.0730312630104
a9609	loss_cnaOV84	134	Etoposide	TOP2	5	14	2.77258872223978	NA	2.03567959587368	2.37175050680826	-0.336070910934577	2.89328368435246	1.37279743980842	0.181970930300252	0.116155533849697	0.244807355542182	0.861632180011648	NA	NA	0.413915427039143	0.813318202629183	85.0730312630104
a9610	loss_cnaOV59	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.71984671521666	2.4953461513971	0.224500563819563	0.932019371003334	1.05744381360089	0.214889426054182	0.240875426846424	0.21230495741904	0.861727511070157	NA	NA	0.198394651930202	0.68113330400466	85.0730312630104
a9611	gain_cnaOV94	1378	Bleomycin (50 uM)	DNA damage	7	25	3.91202300542815	NA	2.13068294734616	2.01704454745734	0.113638399888824	1.98260936001709	2.00875550966467	0.0567184233229028	0.0573175947720957	0.0565715435960614	0.861735687921658	NA	NA	0.134613218618069	0.896398055068722	85.0730312630104
a9612	loss_cnaOV70	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.30244527678366	4.40700389342115	-0.104558616637497	1.25173873843905	0.833953424659051	0.120597625525415	0.0835307028748545	0.125377045702816	0.861831545092252	NA	NA	0.870244742682972	0.89942663353875	85.0730312630104
a9613	loss_cnaOV52, loss_cnaOV53	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	1.36576378071187	1.10979617349193	0.255967607219939	0.478192440900985	1.8076116824794	0.160216181610083	0.535281583995052	0.141605417635298	0.862165885941286	NA	NA	0.538768442770414	0.634393485860173	85.0730312630104
a9614	loss_cnaOV39	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.24893090823539	2.09773450975665	0.151196398478745	1.45759751187488	1.34977822853877	0.109759503603612	0.103729868668796	0.112015733608643	0.862312370572845	NA	NA	0.893451046455334	0.84645293805773	85.0730312630104
a9615	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.16736273455259	5.19322383020697	-0.0258610956543759	0.673986375814235	0.784551652300878	0.0332545949839777	0.03837035373769	0.0329628974440781	0.862332209933997	NA	NA	0.336375054064377	0.95484514313773	85.0730312630104
a9616	loss_cnaOV39	228	KIN001-102	AKT1	9	23	2.32630161961136	NA	2.98408574197472	2.71246763405982	0.27161810791489	1.06525405377344	1.28788330979874	0.220388031528594	0.254979651992631	0.21090273151947	0.862541155367248	NA	NA	0.096621659112947	0.549558313380038	85.0730312630104
a9617	gain_cnaOV19	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-0.519116127321789	-0.762520048660356	0.243403921338567	0.687098239030603	0.942695515925272	0.262195058718373	0.354249083336286	0.258199935426299	0.862579950847539	NA	NA	0.0430251810856222	0.615184215548052	85.0730312630104
a9618	gain_cnaOV51_(MYC)	1006	Cytarabine	DNA synthesis	8	23	0.693147180559945	NA	-0.147367507408102	-0.0987673143405137	-0.0486001930675884	1.56916168219826	1.15898983057815	0.0382623709683246	0.0309720748466811	0.0419332351202295	0.86266015380273	NA	NA	0.768492318788293	0.937605128468898	85.0730312630104
a9619	loss_cnaOV102	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-2.51283296250168	-2.75487434569214	0.242041383190459	0.747202619345401	1.83349885907442	0.135840658264827	0.323930051801081	0.132010653834083	0.86278384132716	NA	NA	0.69793987388461	0.677588221302975	85.0730312630104
a9620	loss_cnaOV21, loss_cnaOV22	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.50648302924532	4.53045569115469	-0.0239726619093741	0.375387770695037	1.02523771295546	0.0240644015801695	0.0638610625620229	0.0233825400747969	0.862926093997942	NA	NA	0.328185620694428	0.936066852499833	85.0730312630104
a9621	loss_cnaOV87, loss_cnaOV88	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	0.189849762562865	0.110383777790278	0.0794659847725869	1.31662178715904	1.65803697556421	0.0485502210092041	0.060355969761108	0.0479277518799274	0.863007409155873	NA	NA	0.464546812437184	0.929651467347477	85.0730312630104
a9622	loss_cnaOV70	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.50671163897164	4.53043283018206	-0.0237211912104209	0.345580252393775	1.02596080987934	0.023811955882735	0.0686416282357232	0.023120952556863	0.863254200320331	NA	NA	0.328186781791033	0.933453507107882	85.0730312630104
a9623	gain_cnaOV4_(KRAS)	176	IPA-3	PAK1, PAK2, PAK3	6	13	3.46573590279973	NA	4.73682272917754	4.77168845613499	-0.0348657269574542	1.58614028433541	1.59328684403854	0.0219117549610526	0.0219814901000783	0.0218828938981755	0.863276638600179	NA	NA	0.125306741428039	0.965414904708468	85.0730312630104
a9624	loss_cnaOV52, loss_cnaOV53	223	ZSTK474	PI3K	8	24	1.63315443905142	2.32630161961136	0.723480682743093	0.769858967075394	-0.0463782843323015	1.12211236693146	1.03553837077775	0.043903290085375	0.0413312300078538	0.0447866401101765	0.863401921825648	NA	NA	0.773215622122431	0.919640943651236	85.0730312630104
a9625	loss_cnaOV35	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	2.55918225585383	2.59243008358107	-0.033247827727243	2.19908130640594	2.37648529349887	0.0141263464650491	0.0151189624641853	0.0139903359882748	0.863413453689898	NA	NA	0.388700934058612	0.976559961201639	85.0730312630104
a9626	loss_cnaOV44	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	3.04003564543137	2.76287656292601	0.277159082505362	0.252998468157826	1.27767454489558	0.224224554129034	1.09549707760469	0.216924633595181	0.863549309403557	NA	NA	0.0966241259314006	0.333268257026346	85.0730312630104
a9627	KRAS_mut	294	MPS-1-IN-1	MPS1	6	25	2.99573227355399	NA	4.42540310357531	4.24987633529758	0.175526768277729	1.03809669137399	0.770533904901461	0.213303780493818	0.169085182272768	0.22779889004388	0.863616169950889	NA	NA	0.319738438265224	0.709750416985212	85.0730312630104
a9628	gain_cnaOV50	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.58855294180494	4.5058265145382	0.0827264272667394	0.882429927013699	0.563982814030427	0.137091881893996	0.0937484379600547	0.146682532177791	0.863674949537446	NA	NA	0.617099055116564	0.865837765145753	85.0730312630104
a9629	loss_cnaOV56	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	0.996909065144357	1.18497036397343	-0.188061298829073	2.92603819616072	1.35171546860005	0.125051627446305	0.0642716486325534	0.139127873578191	0.86368537992466	NA	NA	0.814105943310995	0.921975447084941	85.0730312630104
a9630	loss_cnaOV52, loss_cnaOV53	208	SB-715992	KIF11	8	24	-2.05572501506252	NA	-1.18789048107639	-1.36056857970192	0.172678098625535	1.31971103935194	2.02684623495721	0.0915715731460569	0.130845384691433	0.0851954606360062	0.863754975236971	NA	NA	0.0757326807279147	0.784874459954983	85.0730312630104
a9631	gain_cnaOV95_(MECOM)	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	0.693147180559945	2.90394191176371	2.79279364355051	0.111148268213196	1.69968455301771	1.53295105469195	0.070698396123827	0.0653934684620495	0.072506077655253	0.86380180053335	NA	NA	0.968986583767339	0.872150396811002	85.0730312630104
a9632	loss_cnaOV16, loss_cnaOV17	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.22299846483334	3.82177831316399	0.401220151669353	1.74289601728457	1.47098983486321	0.26521189884674	0.230203149063622	0.272755217038371	0.863829291301767	NA	NA	0.0718449444844123	0.690044202925031	85.0730312630104
a9633	loss_cnaOV41	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.22299846483334	3.82177831316399	0.401220151669353	1.74289601728457	1.47098983486321	0.26521189884674	0.230203149063622	0.272755217038371	0.863829291301767	NA	NA	0.0718449444844123	0.690044202925031	85.0730312630104
a9634	loss_cnaOV42	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.22299846483334	3.82177831316399	0.401220151669353	1.74289601728457	1.47098983486321	0.26521189884674	0.230203149063622	0.272755217038371	0.863829291301767	NA	NA	0.0718449444844123	0.690044202925031	85.0730312630104
a9635	loss_cnaOV35	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	4.69457494807022	4.5038780334273	0.190696914642918	1.35268917758112	0.96238356056725	0.186397809271154	0.1409761516566	0.198150636042159	0.863896522675071	NA	NA	0.193868926059653	0.775766157605419	85.0730312630104
a9636	SMARCA4_mut	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.02357827665575	1.33951019686788	-0.315931920212132	1.94686896045412	1.15543750878416	0.258067462286273	0.162276931128656	0.273430555794038	0.864044543101431	NA	NA	0.0993792148271136	0.806797500246619	85.0730312630104
a9637	gain_cnaOV19	151	QS11	ARFGAP	3	16	2.32630161961136	NA	4.10258531602784	3.70381588137559	0.398769434652247	1.55949313496856	1.45815075076388	0.271191299084812	0.255704514313418	0.273476137116374	0.864063559674305	NA	NA	0.0672207636532693	0.711797614478583	85.0730312630104
a9638	loss_cnaOV87, loss_cnaOV88	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	3	28	2.32630161961136	NA	2.09610536919039	2.31501053063967	-0.218905161449281	0.741810627998706	1.4592999877168	0.153996700748476	0.295095747063984	0.150006964497942	0.864334691017928	NA	NA	0.53238827039627	0.689780097437328	85.0788854409126
a9639	gain_cnaOV94	1059	AZD8055	MTORC1/2	7	26	0.693147180559945	NA	0.467302120726842	0.230999215678926	0.236302905047917	1.48898161304242	1.04401699462507	0.206607202604964	0.158701022885758	0.226340094332255	0.864389464929392	NA	NA	0.149013389398408	0.703908119514043	85.0788854409126
a9640	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	167	OSU-03012	PDPK1 (PDK1)	3	16	2.77258872223978	NA	2.51333870860222	2.27548823874016	0.237850469862057	0.98351319887958	1.27285648666483	0.191456874550216	0.241837598247808	0.186863540669285	0.864422444058839	NA	NA	0.394095209053897	0.736326220025366	85.0788854409126
a9641	gain_cnaOV4_(KRAS)	133	Doxorubicin	DNA intercalating	6	13	0.0237165266173161	NA	-1.68217482481008	-1.52154636363627	-0.160628461173812	0.926282181640345	1.46276499832681	0.12098494602551	0.173412016724058	0.109811529095615	0.864481687849712	NA	NA	0.62564952674154	0.776092938224288	85.0788854409126
a9642	gain_cnaOV19	163	JQ1	BRD4	3	16	0.940007258491471	NA	0.179069225029725	0.0715314606684583	0.107537764361267	2.41011731644972	1.8083009025145	0.0569259895489337	0.0446193069637281	0.059468954647831	0.864679227793458	NA	NA	0.585896482033616	0.947000938096119	85.0895007485757
a9643	gain_cnaOV19	172	Embelin	XIAP	3	16	3.46573590279973	NA	3.15430425454703	3.08742145554258	0.0668827990044507	0.511663947455782	1.01535968493612	0.0689672311225337	0.130716262767821	0.0658710405748076	0.865182649994063	NA	NA	0.674179908577109	0.869658203753828	85.1248512446562
a9644	loss_cnaOV54	1023	GW 441756	NTRK1	10	21	0.693147180559945	NA	2.3332286685162	2.28191624108104	0.0513124274351582	1.54632736579551	1.11892815400835	0.0404962054427556	0.0331834180589312	0.0458585542345514	0.865264771086056	NA	NA	0.845442389339838	0.926565600716727	85.1248512446562
a9645	gain_cnaOV48_(SOX17)	263	FR-180204	ERK	3	29	2.99573227355399	NA	4.72512689929562	4.82072782292989	-0.0956009236342696	0.931732390274716	0.738431578296547	0.126983000290662	0.102605559957063	0.129464836613308	0.865440075109828	NA	NA	0.766534373089458	0.877438353218334	85.1248512446562
a9646	loss_cnaOV21, loss_cnaOV22	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.43124796628479	4.31843758803312	0.112810378251671	0.424423179576035	0.601897218535449	0.190761064964685	0.265796930234489	0.187424654538468	0.865455514211691	NA	NA	0.25683545697488	0.704830516571144	85.1248512446562
a9647	loss_cnaOV36	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	2.78874340983686	2.84988448345483	-0.0611410736179709	1.92801315116914	1.86384695003032	0.0327273814801342	0.0317119588011602	0.0328036986175159	0.865514890020866	NA	NA	0.349100144974726	0.962212574204064	85.1248512446562
a9648	loss_cnaOV83	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-2.55967192502835	-2.76412945509019	0.204457530061847	0.715991372102265	1.89307517640347	0.11475779807731	0.285558650604305	0.108002858317694	0.865582260438472	NA	NA	0.697945991379866	0.678729560020516	85.1248512446562
a9649	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.6033856476899	3.5382678821839	0.0651177655059971	0.948917663626034	0.908649347344838	0.0714489062376509	0.0686231988317796	0.0716643507160133	0.865666469086491	NA	NA	0.665109045066323	0.918383338470845	85.1248512446562
a9650	loss_cnaOV16, loss_cnaOV17	275	I-BET	BRD2, BRD3, BRD4	6	25	2.99573227355399	NA	3.96292660810926	3.90952095208738	0.0534056560218734	0.811857241820416	1.30203296142847	0.0433656853226518	0.0657820775264905	0.041017130598047	0.865953678791124	NA	NA	0.700480439807364	0.901253590937816	85.140638245516
a9651	gain_cnaOV96	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.57254463819807	3.46927131849174	0.103273319706327	0.716530170797784	0.930309231838346	0.113261375242172	0.144129757427161	0.111009668798248	0.866056085574869	NA	NA	0.795346098508809	0.806512969497116	85.140638245516
a9652	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1166	QL-VIII-58	MTOR, ATR	6	17	2.30258509299405	NA	-1.3102681174818	-1.13050744291296	-0.179760674568842	1.1738387570479	1.39033352574752	0.133953940384073	0.153139154325526	0.129293202846557	0.866096209921939	NA	NA	0.0510533898079117	0.765078641863019	85.140638245516
a9653	gain_cnaOV4_(KRAS)	1133	JNJ-26854165	MDM2	7	26	2.30258509299405	NA	3.12487985211835	3.05250414178346	0.0723757103348892	0.98539897098959	0.910747924189565	0.078187675577221	0.0734481285912098	0.0794684329358128	0.86622357125551	NA	NA	0.241467848072943	0.864802130596782	85.1443369426834
a9654	loss_cnaOV70	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	3	30	-1.38629436111989	0.693147180559945	-1.96698816424301	-2.33138123556689	0.36439307132388	1.30409521685083	1.64499662668644	0.2242194898315	0.279422136217805	0.221515999128756	0.866361741718727	NA	NA	0.126382665327273	0.686853244666455	85.1490972331042
a9655	loss_cnaOV85	1061	SB590885	BRAF	7	26	1.6094379124341	NA	3.94542339858676	3.92272501578261	0.0226983828041498	1.85442221863734	1.11834429355448	0.0175424161014158	0.0122401374271869	0.0202964176014227	0.866867859241071	NA	NA	0.57529380432305	0.976181598379322	85.1536390279198
a9656	gain_cnaOV49	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.38767241066874	-4.12487821437997	-0.26279419628877	1.21900136094417	2.43146564242112	0.111091710131085	0.215581544622086	0.108080571530138	0.86715394694342	NA	NA	0.928493460278606	0.771022830675538	85.1536390279198
a9657	loss_cnaOV40	1005	Cisplatin	DNA crosslinker	7	24	1.79175946922805	2.30258509299405	3.12068718769872	2.99524204374026	0.12544514395846	1.32732068472189	1.16632995236024	0.104414963133968	0.0945100497584307	0.107555450929304	0.867260781644724	NA	NA	0.0904022035179012	0.826385081576741	85.1536390279198
a9658	gain_cnaOV49	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.56240545976529	2.50548298555068	0.0569224742146139	0.194765472788279	0.654571455200614	0.0897303650739966	0.292261628304581	0.0869614367726565	0.867268929105051	NA	NA	0.858923950820673	0.739309885507895	85.1536390279198
a9659	SMAD4_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.11692620623474	5.01578242452147	0.101143781713275	1.8647632252377	1.08222200663307	0.0842129838223492	0.0542394768109942	0.0934593651703187	0.86733389173929	NA	NA	0.80283709348395	0.93484969539348	85.1536390279198
a9660	loss_cnaOV55	279	BIX02189	MAP2K5 (MEK5)	7	25	2.99573227355399	NA	4.44045157587854	4.42858782611701	0.0118637497615381	0.903611217435648	0.69829541355139	0.0159479195036933	0.0131292634848051	0.0169895856843761	0.867372850142274	NA	NA	0.526762709477296	0.975126994708816	85.1536390279198
a9661	PIK3CA_mut	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	0.0123360743599176	-0.0845647068167709	0.0969007811766885	0.964645815529154	0.973188468375709	0.099744912875604	0.100452186301699	0.0995704165488313	0.867397923834133	NA	NA	0.551261786952506	0.819501182155388	85.1536390279198
a9662	gain_cnaOV72_(ASXL1)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.29437582722719	2.1478615353999	0.146514291827293	0.791870527848598	1.35939683699066	0.111662240207081	0.185023039341231	0.10777889711119	0.867445507058756	NA	NA	0.688320625494144	0.767863463943757	85.1536390279198
a9663	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1371	PLX4720 (rescreen)	BRAF	3	30	2.30258509299405	NA	4.5096413632774	4.53013985775149	-0.0204984944740891	1.83437518144901	0.910374068292439	0.0205767981273485	0.0111746466488371	0.0225165623539097	0.867460976138721	NA	NA	0.328201412557806	0.986407203013734	85.1536390279198
a9664	loss_cnaOV39	1264	SGC0946	Q8TEK3 (DOT1L)	10	23	-0.693147180559945	NA	2.22102100435494	2.06935178513395	0.151669219220998	0.61833152333822	0.532849425523478	0.271315098514415	0.245287864998655	0.28463804586445	0.867500728261352	NA	NA	0.0434234662111599	0.510248343604997	85.1536390279198
a9665	gain_cnaOV72_(ASXL1)	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	1.43524673717955	1.30384447022877	0.131402266950778	1.74129235163278	1.41868369237105	0.0882600233601103	0.0754624959028646	0.0926226668124762	0.867613908148131	NA	NA	0.858249980729046	0.896804744528306	85.1536390279198
a9666	gain_cnaOV26	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-3.89601517336731	-3.99866785955493	0.102652686187615	1.3446843928777	1.89879410868392	0.0557205969966245	0.0763396130209648	0.0540620416495628	0.867638564190407	NA	NA	0.594318288706583	0.916026234114822	85.1536390279198
a9667	KRAS_mut	1259	BMN-673	PARP1	7	26	2.30258509299405	NA	1.78452505695559	1.93160376231319	-0.1470787053576	1.49099351502923	1.36404082370878	0.105848735222384	0.0986447653024944	0.107825735711999	0.867656844458348	NA	NA	0.035218006416996	0.818943980018764	85.1536390279198
a9668	loss_cnaOV52, loss_cnaOV53	1527	GDC0941 (rescreen)	PI3K	8	23	1.38629436111989	NA	0.327674587449885	0.401274882827183	-0.0736002953772986	0.80285034873083	0.952144625560787	0.0801455448294088	0.0916737415555067	0.077299491486338	0.867664396963452	NA	NA	0.910197706869933	0.834708223250335	85.1536390279198
a9669	ARID1A_mut	177	GSK-650394	SGK3	5	14	2.77258872223978	NA	4.15642134439601	3.88079693925511	0.275624405140897	1.23027662940102	1.65792725956454	0.175799566111697	0.224034496432798	0.166246379960777	0.868021101079492	NA	NA	0.74570068425643	0.704911548151201	85.1704147023554
a9670	loss_cnaOV82	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-3.68773220223946	-3.69153601705633	0.00380381481687486	3.4833374949949	1.5383437960499	0.00218160247399192	0.00109200294899373	0.00247266887066608	0.868197976051192	NA	NA	0.247981927934909	0.998670208182325	85.1704147023554
a9671	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	288	KIN001-055	JAK3, MNK1	3	29	2.32630161961136	NA	3.92291627491484	3.78837445513927	0.134541819775573	1.50106902711758	0.997721802417885	0.129504937004501	0.0896306681072	0.1348490325154	0.868215325016746	NA	NA	0.718769698771552	0.892199038165974	85.1704147023554
a9672	loss_cnaOV21, loss_cnaOV22	341	EX-527	SIRT1	3	28	2.99573227355399	NA	5.78554637922543	5.77200255385386	0.0135438253715758	0.398398560531957	0.580020897087147	0.0237878772912395	0.033995668441903	0.0233505817455762	0.868312051154553	NA	NA	0.112740693664904	0.960949883706391	85.1704147023554
a9673	gain_cnaOV94	1031	Elesclomol	HSP70	7	24	-1.6094379124341	NA	-4.16537340271954	-4.02897279132426	-0.136400611395278	1.48661684365641	1.5490681966102	0.088781932061646	0.0917523650948247	0.0880533288939514	0.868387034554161	NA	NA	0.864900290859627	0.836646429255078	85.1704147023554
a9674	gain_cnaOV49	1114	Cetuximab	EGFR	3	29	4.18661983833127	NA	5.88485450862966	5.81592216103938	0.0689323475902723	0.813316429654481	1.32485765643748	0.0531456164738375	0.0847546478552717	0.0520300028122497	0.868417767497416	NA	NA	0.57319931735165	0.9042182045533	85.1704147023554
a9675	loss_cnaOV36	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.44998560157101	4.28347049442936	0.166515107141651	1.26273090370924	0.761905787640849	0.206468178245878	0.131869036112538	0.21855078389317	0.868463676814997	NA	NA	0.227850683251323	0.84213825441495	85.1704147023554
a9676	loss_cnaOV1	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.37972422603294	4.52580128674857	-0.146077060715639	0.587934368320532	0.949033967618168	0.15730054978098	0.248458107888668	0.153921846530167	0.868779035389663	NA	NA	0.530907788467939	0.727075008635648	85.1925365536963
a9677	gain_cnaOV4_(KRAS)	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	3.97783850165751	3.88063577386864	0.0972027277888734	1.99865198666066	1.65144885273038	0.0562185950916077	0.0486341436316181	0.0588590604112055	0.868882039097942	NA	NA	0.149657499160678	0.909177008854371	85.193832450923
a9678	loss_cnaOV42	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	1.87719755636807	1.52073046628849	0.356467090079578	1.35008172532788	1.65832290405839	0.218674864666774	0.264033712472485	0.214956381056548	0.869039253511606	NA	NA	0.0804970355651833	0.65475571771823	85.1939365662324
a9679	gain_cnaOV51_(MYC)	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.00197817693034	3.13226894054791	-0.130290763617564	0.418533288085628	1.08258976833553	0.134567148692386	0.311303228026412	0.120351002224863	0.869062677913801	NA	NA	0.67419615356913	0.71013228842046	85.1939365662324
a9680	gain_cnaOV4_(KRAS)	282	EKB-569	EGFR	8	24	0.916290731874155	2.99573227355399	1.75962604472072	1.65826896433111	0.101357080389607	1.35524250298567	1.53586883621365	0.0677667784130742	0.0747888884582002	0.0659933179186586	0.869346339666677	NA	NA	0.329227217924295	0.862123234605336	85.2129399380527
a9681	gain_cnaOV4_(KRAS)	177	GSK-650394	SGK3	6	13	2.77258872223978	NA	3.8876152913575	3.9836593941082	-0.0960441027507031	0.842893223745525	1.79065607167385	0.061082504945876	0.113945752611364	0.0536362645345536	0.869519859096652	NA	NA	0.74570564811958	0.875581786579749	85.2186503716801
a9682	loss_cnaOV38	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	7	24	2.32630161961136	NA	2.30844573570706	2.28956211731386	0.0188836183932062	1.37124504437512	1.43624852910147	0.0132698844170533	0.0137711479583224	0.0131478765760825	0.869653215352206	NA	NA	0.532405025793698	0.975314031384375	85.2186503716801
a9683	loss_cnaOV20	167	OSU-03012	PDPK1 (PDK1)	4	15	2.77258872223978	NA	2.30804551282271	2.31437639295723	-0.00633088013451566	0.994086653754566	1.29325780325377	0.00508220793215696	0.00636853951373812	0.00489529629636681	0.869674041347358	NA	NA	0.394128502746884	0.991904101179936	85.2186503716801
a9684	loss_cnaOV82	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	NA	1.22524633469597	1.21514067628137	0.0101056584145922	1.22537003954481	1.25037357598187	0.00809245376138902	0.00824702586848474	0.00808211130554051	0.869885747900375	NA	NA	0.269608665029055	0.990187527891978	85.2217501261129
a9685	PTEN_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.73996251275575	4.47784291318652	0.262119599569232	0.746332805963812	0.943738854358835	0.283289028451059	0.351210073407843	0.277745902225582	0.869963570910943	NA	NA	0.53091145893555	0.557948957112056	85.2217501261129
a9686	gain_cnaOV18_(CCNE1)	1042	BIRB 0796	p38, JNK2	4	29	2.30258509299405	NA	4.45415902892989	4.38968332818159	0.0644757007483037	0.996767522236819	0.852247813710256	0.0743418517456848	0.0646847929029785	0.0756537003804199	0.869975128360154	NA	NA	0.870252359584184	0.908385684048026	85.2217501261129
a9687	gain_cnaOV96	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.39346976148795	4.5291751726336	-0.13570541114565	0.48487007366382	0.966708651966191	0.146150540143226	0.279879948292581	0.140378810999196	0.870111323128538	NA	NA	0.530911914348323	0.669886737838684	85.2262926917617
a9688	PIK3R1_mut	1262	UNC1215	LMBL3	5	28	0	NA	2.71591576511251	2.79193001515149	-0.0760142500389849	0.189016364856345	0.528643629387951	0.152635928512272	0.40215697776622	0.143791102007589	0.870214598311622	NA	NA	0.11164729661747	0.568613761043652	85.2276102211348
a9689	loss_cnaOV36	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.773402683004087	-0.819938549816485	0.0465358668123986	1.10377974060271	0.787543069952328	0.0572178887009113	0.0421604647200609	0.0590899324594598	0.870792303829865	NA	NA	0.0804914886558566	0.949196599779381	85.2652500951246
a9690	gain_cnaOV51_(MYC)	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.56235443135067	2.46710388320269	0.0952505481479786	0.669839241654815	0.812563529419823	0.121908158738008	0.14219911618296	0.117222278258031	0.870910378281525	NA	NA	0.751837291842361	0.802909831974194	85.2652500951246
a9691	PIK3R1_mut	1143	HG-5-88-01	EGFR, ADCK4	5	17	2.30258509299405	NA	3.95128696576047	3.52656476012468	0.424722205635791	0.916210999176862	0.892300021621152	0.473421566337741	0.463563748980713	0.475985873971117	0.8709196482164	NA	NA	0.0619310670388457	0.392506194180861	85.2652500951246
a9692	loss_cnaOV38	1052	RO-3306	CDK1	8	25	1.6094379124341	NA	3.54492949892798	3.46158443190516	0.0833450670228175	1.12588861678934	0.839036369721852	0.0914139400962485	0.0740260322202121	0.099334272065521	0.871026705602576	NA	NA	0.79535317997227	0.851022326949854	85.2652500951246
a9693	loss_cnaOV56	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.40845910137784	3.29147382233869	0.116985279039152	0.68072427618331	1.14029915006234	0.104866235145447	0.171854131154344	0.102591744484557	0.871086739985235	NA	NA	0.951213378152546	0.808761786767642	85.2652500951246
a9694	loss_cnaOV20	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.62231575376644	4.46394586292174	0.158369890844705	0.910965111660705	0.634802003070263	0.233034493188572	0.173848469955116	0.249479192061049	0.871138101223445	NA	NA	0.0547876190646363	0.725989569308724	85.2652500951246
a9695	loss_cnaOV34	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.81960623434488	5.70922771114616	0.110378523198717	0.928840958622436	0.542014378463635	0.181549096849186	0.118834685501401	0.203645009402869	0.871464726540392	NA	NA	0.194893996437737	0.807944166182172	85.2884214631607
a9696	loss_cnaOV34	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	5	27	2.30258509299405	NA	0.972325387682326	0.850165106627598	0.122160281054728	2.25732017682234	1.01767481565348	0.0972787301858689	0.0541173920780234	0.120038620564945	0.871635952066845	NA	NA	0.845791189318354	0.910776096840103	85.2890276324035
a9697	gain_cnaOV96	204	Tipifarnib	Farnesyl-transferase (FNTA)	4	15	2.77258872223978	NA	1.85426490059203	1.8624596501624	-0.00819474957037469	1.67405873235872	1.69092881082366	0.00485481302915784	0.0048951386304281	0.00484630075371592	0.871650697684433	NA	NA	0.350914614337401	0.993424771457113	85.2890276324035
a9698	gain_cnaOV48_(SOX17)	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.56034120213593	2.50569652944337	0.0546446726925622	0.194621579985709	0.654593360387297	0.0861372630076622	0.280773965027799	0.0834788068431234	0.871849915780561	NA	NA	0.858928628318663	0.74923162050459	85.299724161008
a9699	RB1_mut	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.31834037497409	2.34646544316964	-0.028125068195552	1.68663281448311	1.55701693840503	0.0179632194473538	0.0166752762984582	0.0180634311045856	0.87201980131151	NA	NA	0.244778290440262	0.980056812961283	85.3033053691784
a9700	NF1_mut	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.80517419935164	3.58262994186196	0.222544257489681	1.10395994806316	0.873655246821096	0.24404018463112	0.201587256747968	0.254727775400464	0.872153298574408	NA	NA	0.0619343222896807	0.725372803440093	85.3033053691784
a9701	SMAD4_mut	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.40760354372578	3.29156232830269	0.116041215423083	0.682177719612115	1.14024647314615	0.10401913823589	0.170104082978646	0.101768537027704	0.872166183327791	NA	NA	0.951213756741741	0.810590753562407	85.3033053691784
a9702	loss_cnaOV39	1194	SB-505124	TGFR1 (ALK5)	9	23	2.30258509299405	NA	4.62591261869093	4.57377289596202	0.0521397227289091	1.21149434774063	0.837861737616573	0.0547717399951624	0.0430375286736968	0.0622295068363291	0.872246134349671	NA	NA	0.94347453228215	0.90778359703868	85.3033053691784
a9703	NF1_mut	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	4.8322304475045	4.78976216292565	0.0424682845788507	1.06354604153757	0.610272061693107	0.0634277744857209	0.0399308378953244	0.0695891017213354	0.872476111227895	NA	NA	0.763447759171429	0.942301302070233	85.317002729751
a9704	NF1_mut	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	4.95045251532264	5.07794059402704	-0.127488078704396	1.16947110327002	0.526040124128543	0.205249137405592	0.109013449197608	0.242354286026371	0.872680697464962	NA	NA	0.112594023056498	0.842882652071162	85.3282146432499
a9705	gain_cnaOV18_(CCNE1)	163	JQ1	BRD4	4	15	0.940007258491471	NA	0.140927075034163	0.0745335163765238	0.0663935586576388	1.96933058350437	1.87172798980147	0.035141540307613	0.0337137701581281	0.0354717987973674	0.873144703896122	NA	NA	0.585938967731085	0.954294068220353	85.3647869947989
a9706	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	164	JQ12	HDAC	3	16	1.63315443905142	NA	1.90876973288033	1.77235368082521	0.136416052055129	3.00896742730338	2.12060592319216	0.0608063144851521	0.0453365000954443	0.0643288083670826	0.873363727947312	NA	NA	0.663771461526234	0.945963821125817	85.3753195786514
a9707	PIK3CA_mut	1239	YK 4-279	RNA helicase A	7	17	2.30258509299405	NA	1.31475046867659	1.67440978533333	-0.359659316656742	0.978512060584428	1.08039633588089	0.341366421915284	0.367557367092574	0.332895720498255	0.873432394603156	NA	NA	0.29083174418596	0.442449971253606	85.3753195786514
a9708	loss_cnaOV82	224	AS605240	PI3Kgamma	3	29	2.99573227355399	2.32630161961136	3.46917470604283	3.36536931624095	0.10380538980188	0.658203827583114	1.73241934276319	0.0617050945704447	0.157710097467904	0.0599193204783272	0.873572279556827	NA	NA	0.631772904482739	0.842116059592327	85.3801971661898
a9709	gain_cnaOV95_(MECOM)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.55139217467932	1.56561222460401	-0.0142200499246972	0.825406329143349	1.12198915259662	0.0131109073642471	0.0172279390436168	0.0126739638184449	0.873966146332447	NA	NA	0.457924321749266	0.977682523107905	85.4098945738148
a9710	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.55172975652084	1.2753432683233	0.276386488197541	1.18599539408782	1.22845655975019	0.225754917024798	0.233041788842796	0.224986781993939	0.874272278444657	NA	NA	0.0994034458226904	0.686774111901805	85.4202166380223
a9711	gain_cnaOV95_(MECOM)	179	5-Fluorouracil	DNA antimetabolite	8	23	3.46573590279973	NA	3.99029610352736	3.87207648940135	0.118219614126008	1.89045141129547	1.67395529828461	0.0683865368740834	0.0625351243727527	0.070622921799139	0.874426711456492	NA	NA	0.149673720643556	0.878236135732994	85.4202166380223
a9712	gain_cnaOV49	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.49915945172728	4.59767282138493	-0.0985133696576508	0.664284707888194	0.969069343161003	0.10350308444947	0.14829992093425	0.101657709381571	0.874430274921857	NA	NA	0.943475407192997	0.831234511250664	85.4202166380223
a9713	gain_cnaOV72_(ASXL1)	221	TAK-715	p38a	5	27	2.99573227355399	2.32630161961136	4.31377615051337	4.27130396922342	0.0424721812899547	0.866221437896872	0.908631426871439	0.0470297476032531	0.0490315517855045	0.0467430247665911	0.874468872296672	NA	NA	0.523985711770907	0.923788043626843	85.4202166380223
a9714	gain_cnaOV18_(CCNE1)	306	TG101348	JAK2	4	28	2.32630161961136	NA	2.76535062093161	2.8324454750027	-0.0670948540710947	1.9287330876597	1.33795630745601	0.0476447670204957	0.0347870083737232	0.0501472684101835	0.874521902797359	NA	NA	0.629471034409424	0.950084209933591	85.4202166380223
a9715	TP53_mut	1023	GW 441756	NTRK1	21	10	0.693147180559945	NA	2.27683494598597	2.34389938821585	-0.0670644422298881	1.2761609771257	1.24614029537446	0.0529350109486925	0.0525517105067241	0.0538177302177164	0.874678265957588	NA	NA	0.845453242025339	0.890989717352978	85.426695457124
a9716	loss_cnaOV36	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.34462182956521	4.39162899874188	-0.047007169176676	0.655811793479968	1.01328467777623	0.0473164772137279	0.0716778344702212	0.0463908812672847	0.874913772020997	NA	NA	0.513952476174657	0.918292396642353	85.4384613552399
a9717	gain_cnaOV51_(MYC)	1004	Vinblastine	Microtubules	8	23	-2.30258509299405	NA	-3.01719690588549	-3.41883713556984	0.401640229684353	1.89710497504512	1.80714874438313	0.219563434450877	0.211712179856995	0.222250786457233	0.875122598370392	NA	NA	0.141796039399869	0.611330230869404	85.4384613552399
a9718	loss_cnaOV33_(ZFHX3)	1262	UNC1215	LMBL3	4	29	0	NA	2.80334107878622	2.77725017016067	0.0260909086255467	0.835547474894704	0.447857633882608	0.0523151049062206	0.0312261234812956	0.0582571483695769	0.875163111497328	NA	NA	0.111659007858044	0.954742954681286	85.4384613552399
a9719	gain_cnaOV4_(KRAS)	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.00969420249772	3.8666844736557	0.143009728842018	0.871168846328077	1.60293480865657	0.0940779746254329	0.164158451538752	0.0892174329671434	0.875300411763233	NA	NA	0.0718770821182501	0.808151907781568	85.4384613552399
a9720	MLL2_mut	1149	TW 37	BCL2, BCL2L1	3	30	1.6094379124341	NA	-1.45775929972704	-0.668655731419831	-0.789103568307213	0.920833764532422	0.899870811217224	0.875577362306117	0.856944650273442	0.876907616594231	0.875386719741108	NA	NA	0.0430428904874347	0.27215604701685	85.4384613552399
a9721	loss_cnaOV33_(ZFHX3)	333	T0901317	LXR	4	28	2.32630161961136	NA	5.02821278739752	4.71408588912517	0.314126898272353	1.36363784820391	1.09380124167458	0.279545815982552	0.230359474611312	0.287188280927012	0.875491557902363	NA	NA	0.00534527916270225	0.684626044549769	85.4384613552399
a9722	loss_cnaOV87, loss_cnaOV88	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.11271477375598	0.992949780096562	0.119764993659418	0.370255124478446	1.61341151760194	0.0766921733065065	0.323466133866811	0.0742309028743193	0.875555246944	NA	NA	0.792208462366493	0.749762113109343	85.4384613552399
a9723	gain_cnaOV95_(MECOM)	1230	IOX2	EGLN1	8	24	-2.30258509299405	NA	-0.0249492007558858	-0.0761738143271985	0.0512246135713127	0.854334748738421	1.00520254993499	0.0526949819394088	0.0599584807324705	0.0509594942577745	0.875653884851973	NA	NA	0.551285318814101	0.890429490979644	85.4384613552399
a9724	loss_cnaOV52, loss_cnaOV53	346	THZ-2-102-1	CDK7	8	24	0.916290731874155	2.99573227355399	-1.06829275811279	-1.05646003896647	-0.0118327191463203	1.47889724124012	2.12070108237273	0.00594742830619453	0.00800104213893733	0.00557962611735991	0.875682586845678	NA	NA	0.446252204175545	0.986290683076522	85.4384613552399
a9725	loss_cnaOV54	254	AC220	FLT3	10	22	0.0237165266173161	NA	2.47733509585535	2.52603963644146	-0.0487045405861042	0.618431722453883	0.640804328550957	0.0767997917544824	0.0787549196099592	0.0760053239594045	0.875901178273911	NA	NA	0.858932623219682	0.840508149808009	85.4384613552399
a9726	loss_cnaOV1	1024	CEP-701	FLT3, JAK2, NTRK1, RET	3	28	0.693147180559945	NA	0.185742629029061	-0.194583107297278	0.380325736326339	1.42732839959173	1.63118906148213	0.235065770684921	0.266459867564553	0.233158586767843	0.875912454939491	NA	NA	0.102569187016708	0.698898802529758	85.4384613552399
a9727	TP53_mut	263	FR-180204	ERK	22	10	2.99573227355399	NA	4.82748722044012	4.77717687131709	0.0503103491230368	0.806807758493785	0.609358189020745	0.0668106586027341	0.0623572946509095	0.0825628506016911	0.876006847033763	NA	NA	0.766551714562445	0.847292322331507	85.4384613552399
a9728	gain_cnaOV94	272	AR-42	HDAC	6	24	1.63315443905142	NA	0.306544813283327	0.292236015334529	0.0143087979487988	1.02107445815814	1.9958519877873	0.0076943739646728	0.0140134716273381	0.00716926808017573	0.8760971018518	NA	NA	0.488802790552686	0.980719431197528	85.4384613552399
a9729	KRAS_mut	150	Bicalutamide	ANDR (androgen receptor)	3	16	0.0237165266173161	NA	2.90544502193237	2.98892592754579	-0.0834809056134214	0.104801448377465	0.647571695974659	0.13700017647005	0.796562518036455	0.128913765274707	0.8761167195132	NA	NA	0.851128301548901	0.635243739637535	85.4384613552399
a9730	gain_cnaOV49	308	XL-880	MET	3	29	1.63315443905142	NA	0.27767657565478	0.250555830886392	0.027120744768388	0.627535144555307	0.999516588646603	0.0276989782651306	0.0432178898722982	0.0271338615851398	0.876200844919145	NA	NA	0.371083663560411	0.950861675817556	85.4384613552399
a9731	loss_cnaOV39	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	9	23	2.30258509299405	NA	0.942844042708445	0.840456018825252	0.102388023883193	1.79481294830529	0.989341039554832	0.081537863008967	0.0570466264910061	0.103491131763081	0.876379482576327	NA	NA	0.845796285729254	0.874703529301863	85.4384613552399
a9732	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	5	27	1.63315443905142	NA	2.69308335943024	2.89537547123335	-0.202292111803109	0.921189965303431	0.787220773443623	0.250867499044492	0.219598692367949	0.256969986854135	0.876459172439021	NA	NA	0.020150917579874	0.663740306029893	85.4384613552399
a9733	loss_cnaOV42	309	Y-39983	ROCK	4	28	2.99573227355399	NA	5.13031821045478	4.94057122274122	0.189746987713563	1.83946754995479	1.16126975915521	0.15230742836183	0.10315321285131	0.163396132739733	0.876513971488994	NA	NA	0.375381044728677	0.852530880706974	85.4384613552399
a9734	loss_cnaOV52, loss_cnaOV53	1502	Bicalutamide	ANDR (androgen receptor)	9	23	2.30258509299405	NA	4.51361485491682	4.51716610782773	-0.00355125291091074	0.625538506310485	0.59610859953038	0.00587861586688113	0.00567711319940404	0.00595739251825666	0.87665555885574	NA	NA	0.617132193636806	0.988533639703941	85.4384613552399
a9735	TP53_mut	152	CP466722	ATM	22	10	2.77258872223978	NA	2.62849443555531	2.68744563382065	-0.0589511982653455	0.903815422355595	0.579594577953203	0.0718811982714673	0.0652248200320616	0.101711093422453	0.876795317105933	NA	NA	0.558239094979954	0.82628973796388	85.4384613552399
a9736	gain_cnaOV95_(MECOM)	302	PI-103	PI3Ka, PRKDC (DNAPK)	9	23	2.32630161961136	NA	1.4097274260711	1.24300108419054	0.166726341880557	1.75961099042169	2.52467027069898	0.0710930046402807	0.0947518188895839	0.0660388581493445	0.876912242181672	NA	NA	0.366275391669024	0.834491245020599	85.4384613552399
a9737	TP53_mut	135	Gemcitabine	DNA replication	12	7	0.0237165266173161	NA	-2.1346845705757	-2.23703029434652	0.102345723770821	2.92171929942455	2.22019169434394	0.0379753867218247	0.0350292801197495	0.0460976968932693	0.877235539450449	NA	NA	0.421773879701942	0.932545382701402	85.4384613552399
a9738	loss_cnaOV33_(ZFHX3)	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	3.19706893069477	3.40053423451203	-0.203465303817262	0.764844906505743	1.75363805735716	0.121028412025839	0.266021649731329	0.116024685346928	0.87725067003177	NA	NA	0.63178162068663	0.697377485839403	85.4384613552399
a9739	PTEN_mut	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	2.6925296502314	3.33656965125011	-0.64404000101871	0.316324282160757	1.06466941632377	0.624187101008194	2.03601189456396	0.604920166902636	0.877358223932177	NA	NA	0.09377108002177	0.0416124064677647	85.4384613552399
a9740	KRAS_mut	272	AR-42	HDAC	6	24	1.63315443905142	NA	0.334591801916839	0.285224268176151	0.0493675337406881	2.16748090200023	1.78558431529075	0.0265482318632278	0.0227764561593737	0.0276478311989706	0.877439583143255	NA	NA	0.488807082054438	0.960341597110551	85.4384613552399
a9741	loss_cnaOV58	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.85086407107401	2.77737803354735	0.0734860375266577	1.43809204963435	1.20496263640301	0.0593306633532055	0.0510996758137578	0.0609861545134911	0.877460218089549	NA	NA	0.0966562467738617	0.918506672922468	85.4384613552399
a9742	loss_cnaOV36	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.54945044529974	2.52259390597378	0.0268565393259639	0.677462429363951	1.07086466529328	0.025634418950987	0.0396428468382796	0.025079302918832	0.877519599515701	NA	NA	0.198448711724633	0.955110855858019	85.4384613552399
a9743	RB1_mut	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	5.01352979580094	4.93007637435293	0.083453421448012	0.859239036490635	0.822755388712538	0.101136311365037	0.0971248021841029	0.101431631555281	0.877525819078835	NA	NA	0.946285324443209	0.884735517847734	85.4384613552399
a9744	loss_cnaOV33_(ZFHX3)	1049	PD-173074	FGFR1, FGFR3	4	29	0.693147180559945	NA	3.0426334967711	2.9787687338631	0.063864762908004	1.20935896422624	0.990922179189024	0.0629755717405348	0.0528087729095931	0.0644498268877898	0.877556434786701	NA	NA	0.0894503927474231	0.924920577152819	85.4384613552399
a9745	NF1_mut	1262	UNC1215	LMBL3	4	29	0	NA	2.77751293494732	2.78081267275914	-0.00329973781182469	0.521043203847968	0.496360187064883	0.00661532261761787	0.00633294472983376	0.00664786962737072	0.877652723072095	NA	NA	0.111664722221033	0.991074613290834	85.4384613552399
a9746	PIK3CA_mut	1043	JNK Inhibitor VIII	JNK	7	26	2.30258509299405	NA	4.21345826566155	4.50357636085651	-0.290118095194956	1.02640360353855	1.00659870062703	0.287114247777454	0.282654985031978	0.288216242494886	0.877660768629212	NA	NA	0.377628235116158	0.521178967795922	85.4384613552399
a9747	gain_cnaOV72_(ASXL1)	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.46192951494451	2.38086741428613	0.0810621006583783	0.63804369298479	0.989172714319751	0.0853388846981366	0.127047883318409	0.0819493901164917	0.877705999892138	NA	NA	0.736309464831217	0.819044756267431	85.4384613552399
a9748	loss_cnaOV34	1021	Axitinib	PDGFR, KIT, VEGFR	5	25	0.693147180559945	NA	2.57240583636298	2.51585430461505	0.0565515317479295	0.486469192208366	1.11384194580534	0.0539881201972098	0.116248947834105	0.0507715946242633	0.877862462203453	NA	NA	0.198449810381037	0.858452774202068	85.4384613552399
a9749	gain_cnaOV18_(CCNE1)	173	FH535	unknown 	4	14	3.46573590279973	NA	2.40272742434659	2.52371180600937	-0.120984381662786	1.15880527655314	1.52055451147149	0.0828903135496157	0.104404410396416	0.0795659614634308	0.877916633637225	NA	NA	0.125151856814235	0.869601032722053	85.4384613552399
a9750	loss_cnaOV55	152	CP466722	ATM	7	25	2.77258872223978	NA	2.72174353638614	2.62596516662881	0.0957783697573249	0.742821597110551	0.837678307831436	0.116861931699616	0.128938590544333	0.114337889452186	0.878086929474038	NA	NA	0.558242562122996	0.77516795783117	85.4384613552399
a9751	gain_cnaOV4_(KRAS)	1259	BMN-673	PARP1	7	26	2.30258509299405	NA	1.84453705492689	1.91544668593631	-0.0709096310094115	0.546359893402082	1.5251763543964	0.0509928314998888	0.129785571499164	0.0464927421704453	0.878128447398534	NA	NA	0.0352302573965842	0.846731374408908	85.4384613552399
a9752	PIK3R1_mut	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	1.21183991271714	1.67922475709465	-0.467384844377507	0.588456681810475	1.36639308947315	0.372142022433515	0.794255310245655	0.342057383031497	0.878130445238986	NA	NA	0.167374508305054	0.277357566743209	85.4384613552399
a9753	gain_cnaOV51_(MYC)	1049	PD-173074	FGFR1, FGFR3	8	25	0.693147180559945	NA	3.15844671915299	2.93149014063561	0.22695657851738	0.841823004380109	1.05323103500066	0.22484939901985	0.269601302573697	0.215486033904458	0.878536812951412	NA	NA	0.0894523665277018	0.54319850752148	85.4478575370479
a9754	loss_cnaOV34	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.49619366602151	4.51902069679297	-0.0228270307714622	0.546467188749182	0.610111289627523	0.037790049598284	0.0417720061541323	0.0374145359372029	0.878610613494235	NA	NA	0.617136887852251	0.942216063983756	85.4478575370479
a9755	PTEN_mut	1058	GDC0941	PI3K (class 1)	4	29	1.38629436111989	0.693147180559945	0.368538235456941	0.909434243517651	-0.540896008060709	1.18128979784633	1.36054326280085	0.402380161864071	0.457885955712854	0.397558844947867	0.878678349325343	NA	NA	0.165652933969153	0.445248629805561	85.4478575370479
a9756	PIK3CA_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	1.6094379124341	NA	1.30438187715584	1.13112172979019	0.173260147365647	0.896592202516145	1.61515245036663	0.115266400909051	0.193242978111365	0.107271698920011	0.878742048975265	NA	NA	0.814125098470519	0.713179150989794	85.4478575370479
a9757	loss_cnaOV41	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.0102001988174631	-0.129310706828388	0.139510905645851	1.19460877934023	1.27780586547246	0.109898514710157	0.116783760557077	0.109180047936522	0.878822493792814	NA	NA	0.768519586740217	0.839350192123534	85.4478575370479
a9758	loss_cnaOV42	1006	Cytarabine	DNA synthesis	4	27	0.693147180559945	NA	0.0102001988174631	-0.129310706828388	0.139510905645851	1.19460877934023	1.27780586547246	0.109898514710157	0.116783760557077	0.109180047936522	0.878822493792814	NA	NA	0.768519586740217	0.839350192123534	85.4478575370479
a9759	loss_cnaOV41	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	3.07962382551325	2.80054670822721	0.279077117286041	2.06664658295586	1.83242021284062	0.149611089507641	0.135038627111021	0.152299737434906	0.878900189940017	NA	NA	0.34914566465617	0.788674483908925	85.4478575370479
a9760	NF1_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	4.20861544053296	4.00755767893884	0.201057761594121	2.09533043756407	1.42836462497598	0.133292852575872	0.0959551572342263	0.14076081000501	0.878947467272758	NA	NA	0.332563090567435	0.863087056430234	85.4478575370479
a9761	loss_cnaOV38	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	0.0428652658266486	0.138934325062938	-0.0960690592362891	2.1501808370358	1.10242648868526	0.0712749051830731	0.0446795253597033	0.0871432791413239	0.879049632344183	NA	NA	0.871267103276107	0.935961358305677	85.4490346042828
a9762	gain_cnaOV95_(MECOM)	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	8	24	2.30258509299405	NA	0.813196987645526	0.887937871508024	-0.0747408838624979	1.33391809768684	1.23152905398423	0.0594991845656565	0.0560310891591519	0.0606895010886646	0.879195684904233	NA	NA	0.845799217648491	0.891245472124331	85.4544771273617
a9763	gain_cnaOV4_(KRAS)	305	TPCA-1	IKK	8	24	2.99573227355399	NA	3.38425324763438	3.30550893270028	0.0787443149340996	1.55676934367597	1.1263096029882	0.0634939126979334	0.0505818766627059	0.0699135608230488	0.879525302386577	NA	NA	0.993649395473853	0.897708799522762	85.4618108108424
a9764	RB1_mut	1230	IOX2	EGLN1	3	29	-2.30258509299405	NA	-0.0938418432418818	-0.0602151593163519	-0.0336266839255299	1.44446449309188	0.929455851808986	0.0345841883085206	0.0232796888302542	0.0361788931234149	0.879541213708582	NA	NA	0.551295857653198	0.971832890752017	85.4618108108424
a9765	PTEN_mut	179	5-Fluorouracil	DNA antimetabolite	3	28	3.46573590279973	NA	3.30049639263852	3.96709424666194	-0.666597854023424	1.53912980975925	1.72995916500648	0.388125682890377	0.433100476513863	0.385325773872198	0.879710805918629	NA	NA	0.149688506843799	0.539720388950185	85.4618108108424
a9766	SMARCA4_mut	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.47981708950416	-4.15278547092068	-0.327031618583474	0.616608103272913	1.38432168490268	0.242816742556886	0.530371911831215	0.236239612620433	0.879751454586281	NA	NA	0.220396474607708	0.493125352556507	85.4618108108424
a9767	SMARCA4_mut	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.68695035416534	5.73056304517844	-0.0436126910131023	0.438519546913287	0.619645063142388	0.0715845109245346	0.0994543830944126	0.0703833429930524	0.879885021045021	NA	NA	0.194919421588325	0.885653255385005	85.4618108108424
a9768	KRAS_mut	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.65274400963599	-2.76498782736101	0.112243817725024	2.10950400590866	1.0755852700891	0.0903223426071123	0.0532086298061691	0.104356038378739	0.879907192499822	NA	NA	0.383924481907636	0.935828575048643	85.4618108108424
a9769	loss_cnaOV35	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	-1.38629436111989	0.693147180559945	-2.25506649446547	-2.100095377257	-0.154971117208474	1.74706840078664	1.22301451497291	0.118976419191929	0.0887035202163215	0.126712410450752	0.879975870078153	NA	NA	0.609593882126857	0.857051482294413	85.4618108108424
a9770	gain_cnaOV4_(KRAS)	221	TAK-715	p38a	8	24	2.99573227355399	2.32630161961136	4.3204639419065	4.26376568276446	0.0566982591420393	0.991928808954916	0.873974151202249	0.0627973726337623	0.0571596052359603	0.0648740687170719	0.879991703664651	NA	NA	0.524001355478266	0.888059120757463	85.4618108108424
a9771	NF1_mut	1495	AZD-2281	PARP1, PARP2	4	29	2.30258509299405	NA	3.56060588926442	3.56132331101009	-0.000717421745663582	0.857258421471699	0.931528999181242	0.000775924683056057	0.000836879204326681	0.000770155031452755	0.880276701985058	NA	NA	0.1451268349664	0.998835111693994	85.4801232125736
a9772	loss_cnaOV84	1006	Cytarabine	DNA synthesis	6	25	0.693147180559945	NA	-0.0109333147168164	-0.135399536031829	0.124466221315013	1.25016779048521	1.27331593919673	0.0980546984198237	0.099559612927402	0.0977496766384091	0.88036044482806	NA	NA	0.768521997817092	0.832933859016372	85.4801232125736
a9773	loss_cnaOV83	1230	IOX2	EGLN1	5	27	-2.30258509299405	NA	-0.0482939379568214	-0.0661590911153979	0.0178651531585765	1.29091881839941	0.9135237477228	0.0183732955608254	0.0138390988681435	0.0195563095136936	0.880544994846034	NA	NA	0.551298522890593	0.977582067204418	85.4820587590768
a9774	loss_cnaOV38	269	NSC-207895	MDM4	8	23	2.99573227355399	NA	3.85294879059842	3.8961070113697	-0.0431582207712831	1.05523551018037	1.74277585719868	0.0269061023244073	0.0408991361216662	0.0247640685364182	0.880605851084507	NA	NA	0.717268086709786	0.934754640623715	85.4820587590768
a9775	loss_cnaOV84	1005	Cisplatin	DNA crosslinker	6	25	1.79175946922805	2.30258509299405	3.24698338478823	2.96994876219712	0.277034622591113	1.35537762250969	1.16165912153116	0.231383361606184	0.204396633078641	0.238481855353539	0.880650655452343	NA	NA	0.0904321989458648	0.658601751850536	85.4820587590768
a9776	loss_cnaOV59	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.01431685835337	3.86571128294924	0.148605575404124	1.82299012396568	1.46345736691281	0.0977645960065604	0.0815174879175165	0.101544178029326	0.880916200959456	NA	NA	0.0718917536827854	0.886075842337047	85.4990877374591
a9777	loss_cnaOV54	1008	Methotrexate	Dihydrofolate reductase (DHFR)	10	21	-1.6094379124341	NA	0.688734098843413	0.507121418893759	0.181612679949654	1.1226185960205	1.2607188268816	0.148919631842336	0.161775941173113	0.14405486463534	0.881052032821429	NA	NA	0.43372476311731	0.690267662981693	85.4998474631115
a9778	loss_cnaOV52, loss_cnaOV53	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	5.04078693677463	4.66063940149621	0.380147535278415	1.61458854884687	1.57105924935773	0.240385301179132	0.235445454849729	0.241968936202645	0.881189040618012	NA	NA	0.125389467852584	0.66296110427189	85.4998474631115
a9779	gain_cnaOV26	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	2.05430836017727	2.23885494618923	-0.184546586011957	0.419449223368336	1.40567135126742	0.139467643792252	0.439973602835591	0.131287150332516	0.881218873597007	NA	NA	0.689301166931975	0.679653593885494	85.4998474631115
a9780	gain_cnaOV4_(KRAS)	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	7	26	0.693147180559945	NA	2.74826928693748	2.81121925830769	-0.0629499713702009	1.14488157495383	0.922652239297094	0.0649204729529927	0.0549838278013511	0.0682271918812641	0.881352879970893	NA	NA	0.966387517150031	0.89646240132483	85.4998474631115
a9781	loss_cnaOV34	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.9997303053171	2.74981021239122	0.249920092925881	0.421141756432128	1.31664756434805	0.20230858550168	0.593434607489838	0.189815482664589	0.881422993341451	NA	NA	0.0966647458225204	0.437448849816051	85.4998474631115
a9782	PIK3R1_mut	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.57443693204838	5.75462943379366	-0.180192501745278	0.406346892357662	0.630726045122237	0.29752849195118	0.443445010000655	0.285690599173459	0.881487465430594	NA	NA	0.194924059153677	0.433188516594454	85.4998474631115
a9783	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-2.03042108175966	-1.98254950166162	-0.0478715800980347	3.0820057422659	1.84836888163937	0.0233553823421064	0.0155326057448677	0.0258993648797939	0.881636549639579	NA	NA	0.281026665323179	0.974575276313823	85.4998474631115
a9784	PIK3CA_mut	300	CX-5461	RNA Pol I	6	25	2.32630161961136	NA	3.32355744185723	3.59120173692437	-0.267644295067139	1.4219803326445	1.77576139362634	0.155610390469567	0.188219407064086	0.150720866005863	0.881995937100812	NA	NA	0.70029283293635	0.70309406555337	85.4998474631115
a9785	gain_cnaOV96	283	GSK2126458	PI3K, MTOR	5	27	-2.05572501506252	0.0237165266173161	-2.79457176231756	-2.72062948522182	-0.0739422770957407	1.50024699625162	1.82269849241416	0.041468913006908	0.0492867356378557	0.0405674758625627	0.882015837299931	NA	NA	0.697979283527227	0.92517983251087	85.4998474631115
a9786	loss_cnaOV40	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	2.33095046376269	1.94555377532313	0.385396688439566	2.8340480110467	1.6600608836648	0.193015273264748	0.135988059107449	0.232158164939561	0.882100503910477	NA	NA	0.134668063275862	0.724328170632252	85.4998474631115
a9787	loss_cnaOV39	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	9	22	3.68887945411394	NA	3.41561080253386	3.51988361552797	-0.104272812994109	0.843002985481524	1.21192441700025	0.0929073248256794	0.123692104049368	0.0860390396722962	0.882350369335139	NA	NA	0.728409485703515	0.787352312910673	85.4998474631115
a9788	NF1_mut	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	3.0384984010069	2.83880574701515	0.199692653991751	0.92265286941699	0.79316989709778	0.247434198674111	0.216433136026482	0.251765296089059	0.882591549740365	NA	NA	0.0201556147196679	0.703513725122058	85.4998474631115
a9789	gain_cnaOV96	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.27108406623763	5.11861599025294	0.152468075984696	0.546336962212226	0.595109297240565	0.258929650357107	0.279073331167861	0.256201804763709	0.882598049952344	NA	NA	0.012347037155897	0.592846070690347	85.4998474631115
a9790	loss_cnaOV38	292	Masitinib	KIT	8	24	2.99573227355399	NA	4.1736723344027	3.96013644903747	0.213535885365229	1.27674071410187	0.976860742790982	0.202501871708485	0.16725078397413	0.218593987875014	0.882731775007214	NA	NA	0.106676280639471	0.674509535410019	85.4998474631115
a9791	loss_cnaOV59	345	KIN001-270	CDK9	4	28	2.99573227355399	NA	5.18803299399366	5.19119454656018	-0.00316155256652539	0.551858189837071	0.798870787632614	0.00406521768968145	0.00572892207590287	0.0039575268184413	0.882772796976746	NA	NA	0.336444502442493	0.992367677602248	85.4998474631115
a9792	loss_cnaOV34	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	2.86034989261599	2.78670843791008	0.0736414547059066	1.38588516723306	0.891582840322464	0.0759481291398494	0.0531367651859156	0.0825963122835251	0.882793017250639	NA	NA	0.966387825362027	0.913542673858726	85.4998474631115
a9793	gain_cnaOV4_(KRAS)	153	Midostaurin	KIT	6	13	-0.669430653942629	NA	0.177754523351702	0.0914575999338807	0.086296923417821	0.433024050327292	1.57970657965464	0.0640263081010661	0.199288984878774	0.05462845095998	0.882827262205109	NA	NA	0.871272999231606	0.857472128426708	85.4998474631115
a9794	gain_cnaOV26	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.29843796989885	0.391264467675991	-0.0928264977771414	1.51445461383816	0.85804225179651	0.101063338239535	0.0612936808597297	0.10818406387656	0.882858645213134	NA	NA	0.910207544132709	0.925833903639717	85.4998474631115
a9795	gain_cnaOV94	1067	CCT007093	PPM1D	7	26	1.88706964903238	NA	4.6127549809886	4.45660535109422	0.156149629894373	0.567004615583893	0.731607783912849	0.222193409704324	0.275393930847587	0.213433527264076	0.882936634464954	NA	NA	0.0831355341860029	0.556148128424963	85.4998474631115
a9796	loss_cnaOV85	224	AS605240	PI3Kgamma	7	25	2.99573227355399	2.32630161961136	3.40278535178586	3.36734947306459	0.0354358787212705	1.73836530139494	1.6682470812838	0.0210613869987501	0.0203845985034533	0.0212413851154476	0.882974673625932	NA	NA	0.63179465613177	0.962659204480611	85.4998474631115
a9797	NF1_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-2.02394481187604	-1.98509352440757	-0.0388512874684765	1.4504834696369	2.1038431693102	0.0189542790726803	0.026785060486213	0.0184668173156723	0.882998480921813	NA	NA	0.281030750008555	0.964227534684805	85.4998474631115
a9798	gain_cnaOV72_(ASXL1)	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.08138261548943	2.99659078056326	0.0847918349261669	1.14974573254598	1.69826272805336	0.0518354369290443	0.0737483362851065	0.0499285731974817	0.883053925482807	NA	NA	0.665327248114266	0.892889400956089	85.4998474631115
a9799	loss_cnaOV57_(ZNRF3)	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.16959550957684	4.30077573946608	-0.131180229889242	0.681902291047589	0.839682152963397	0.159052413177732	0.192373939216003	0.15622605461636	0.883206040794098	NA	NA	0.319806915701491	0.743837906744315	85.4998474631115
a9800	gain_cnaOV18_(CCNE1)	1067	CCT007093	PPM1D	4	29	1.88706964903238	NA	4.53296061474499	4.48376488056517	0.0491957341798122	1.11486335625252	0.646623651702122	0.0697169471799916	0.0441271424914152	0.0760809383484708	0.883448311933797	NA	NA	0.0831364799893997	0.936242720083287	85.4998474631115
a9801	ARID1A_mut	133	Doxorubicin	DNA intercalating	5	14	0.0237165266173161	NA	-1.7848944134358	-1.49633425778236	-0.288560155653438	1.04687985897388	1.39729105668537	0.218074833261806	0.275638272319305	0.206513993110323	0.883463753441365	NA	NA	0.6257340337593	0.640802175826279	85.4998474631115
a9802	loss_cnaOV54	193	GW-2580	CSF1R (cFMS)	10	22	2.99573227355399	NA	5.75727615836982	5.71247353586239	0.0448026225074267	0.508570923158923	0.647303957433928	0.0735661357257186	0.0880951318041169	0.0692141952677616	0.88359771495248	NA	NA	0.194930068567897	0.834509539737957	85.4998474631115
a9803	loss_cnaOV33_(ZFHX3)	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	3.97147763368471	3.91221010800375	0.0592675256809607	1.09343160296499	1.24649203287878	0.0481247003977261	0.0542032309293498	0.047547456475981	0.883620755343054	NA	NA	0.700516954031779	0.925433113846641	85.4998474631115
a9804	loss_cnaOV35	1049	PD-173074	FGFR1, FGFR3	5	28	0.693147180559945	NA	3.17187420401549	2.95340915175131	0.218465052264178	1.11521194252383	0.994776453863077	0.216061815415212	0.195895545890381	0.219612206758412	0.883823480819088	NA	NA	0.0894627287765154	0.698227922448657	85.4998474631115
a9805	PIK3R1_mut	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-1.58777964552337	-2.28200549817275	0.694225852649378	3.68027625083005	2.51947445514119	0.258823013578949	0.188634169104236	0.275543914022528	0.883935072505187	NA	NA	0.421811285698533	0.779613603702043	85.4998474631115
a9806	gain_cnaOV72_(ASXL1)	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-4.33109208820384	-4.15610257348863	-0.174989514715208	0.928689656293286	1.40233104924566	0.129734978353078	0.188426255778115	0.124784739530183	0.883963988137116	NA	NA	0.220408986780035	0.733136941276626	85.4998474631115
a9807	loss_cnaOV42	257	NPK76-II-72-1	PLK3	4	28	2.32630161961136	NA	3.3594113709002	3.21116915488911	0.148242216011081	0.995268008483479	1.26439628706971	0.119539134502306	0.148947032103405	0.117243476216335	0.883969806271513	NA	NA	0.603083521448018	0.800111928030541	85.4998474631115
a9808	loss_cnaOV20	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	5	28	-1.38629436111989	0.693147180559945	-2.01938174615575	-2.34805331531989	0.328671569164143	1.77961551854366	1.59990106105965	0.202358081749274	0.184686841477484	0.205432434019674	0.883982988732996	NA	NA	0.126426080047591	0.714688958473264	85.4998474631115
a9809	gain_cnaOV26	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	2.68728127617062	2.52202092906354	0.165260347107078	1.67001712823334	0.984628280068887	0.158517907935343	0.0989572767327853	0.167840341834906	0.883985700152079	NA	NA	0.397823056171227	0.880778876411696	85.4998474631115
a9810	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.71652710099317	1.45718559588838	0.259341505104793	0.772945378714077	1.8181801020513	0.151131114522569	0.335523715189618	0.142637962439584	0.883987798731078	NA	NA	0.318955959729463	0.606195220281119	85.4998474631115
a9811	gain_cnaOV95_(MECOM)	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.20571595254937	2.11435564655897	0.0913603059904031	1.27363204094281	1.4120031074285	0.0662649249421445	0.0717321039778283	0.0647026238892534	0.884146919237532	NA	NA	0.89348330872883	0.898083116076476	85.5065214359553
a9812	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.48417169226951	1.78307716248373	-0.298905470214226	1.86000245925298	1.68802287625431	0.17467744080927	0.160701653230219	0.177074300602781	0.884552789418328	NA	NA	0.231894700329928	0.750241682629072	85.5210037250962
a9813	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1006	Cytarabine	DNA synthesis	8	23	0.693147180559945	NA	-0.0470493257915488	-0.133660594902793	0.0866112691112444	1.3352521897445	1.24821231456014	0.0682102926253243	0.0648651017212095	0.0693882507814908	0.884586905929257	NA	NA	0.76852846032451	0.875129221981399	85.5210037250962
a9814	loss_cnaOV81_(RB1)	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.4368631323754	3.48798600895004	-0.051122876574647	1.15973395455677	0.881697000010509	0.0560364539470899	0.0440815554065461	0.057982364206794	0.884609776373187	NA	NA	0.795371120446698	0.937016630908334	85.5210037250962
a9815	loss_cnaOV82	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.25921445798718	2.36702368677439	-0.107809228787215	1.53375111527809	0.806731876443506	0.123320952744493	0.0702912146001391	0.133637001258081	0.884663478581394	NA	NA	0.65250010807069	0.914884877449452	85.5210037250962
a9816	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.68093859336725	2.88268064621896	-0.20174205285171	0.733542034764396	0.812685441358301	0.249788795097991	0.275024529325722	0.248241253730993	0.884747333633907	NA	NA	0.0201572076683181	0.689127679554471	85.5210037250962
a9817	loss_cnaOV44	333	T0901317	LXR	3	29	2.32630161961136	NA	5.03435184527801	4.72428277618141	0.310069069096601	1.40765677811097	1.10198420424309	0.275629355299635	0.220273204319524	0.281373424321971	0.885434826148544	NA	NA	0.00534795435677002	0.743227260120768	85.5705827168854
a9818	gain_cnaOV50	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.02962981485028	1.24177379424579	-0.212143979395515	0.691693433384234	1.2921384717387	0.170159750510216	0.306702318045094	0.164180530210554	0.885470972531603	NA	NA	0.269657046367233	0.631088455559002	85.5705827168854
a9819	loss_cnaOV1	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-3.96557318492287	-4.2059831162222	0.240409931299322	1.23126317839589	1.35646244044334	0.178282492230916	0.195254707131364	0.177233017392466	0.885530803484458	NA	NA	0.220413523524498	0.7743486274297	85.5705827168854
a9820	loss_cnaOV20	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	2.58649329222008	2.58737248425399	-0.000879192033907739	1.6678526679226	2.44210900034065	0.000373546122905632	0.000527140107047236	0.00036001342846904	0.885705376840494	NA	NA	0.388774304236335	0.999229906180616	85.5787364570492
a9821	gain_cnaOV18_(CCNE1)	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.39909601440172	-3.47181235334966	0.0727163389479482	2.77822341451815	1.49887698851255	0.0405720200857953	0.0261736829975425	0.0485138803952886	0.885797698440155	NA	NA	0.684607371644383	0.962541144338341	85.5789420063991
a9822	TP53_mut	274	PXD101, Belinostat	HDAC	20	10	2.99573227355399	NA	0.830969401631087	0.902346504805995	-0.071377103174908	2.16481796303502	1.93643537034345	0.034084414518847	0.0329714111734546	0.0368600492781995	0.885962714138999	NA	NA	0.418921961740522	0.928049072215869	85.5822460757996
a9823	loss_cnaOV38	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	8	25	-2.30258509299405	NA	-0.409667152638837	-0.307894492800427	-0.10177265983841	1.72916462783879	1.31342401898121	0.0717721979597668	0.0588565473754867	0.0774865225301365	0.886012293165202	NA	NA	0.889607978550852	0.881564000911472	85.5822460757996
a9824	PTEN_mut	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.30296515648746	2.29780248599682	0.00516267049064689	0.379229970045169	1.33224010924519	0.00407364746217401	0.0136135614229856	0.00387518019823913	0.886241606518042	NA	NA	0.845465463097628	0.987268178991564	85.5859507002203
a9825	KRAS_mut	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.472594352135226	-0.570895164047734	0.0983008119125081	0.83629254356646	1.57559093909047	0.0652056275728028	0.11754357092949	0.0623898052937862	0.886344083710328	NA	NA	0.910178101882073	0.880551719836845	85.5859507002203
a9826	gain_cnaOV95_(MECOM)	1007	Docetaxel	Microtubules	8	23	-4.38202663467388	NA	-4.54929568522433	-4.68310691599965	0.133811230775322	1.60530132309225	1.37199361568637	0.0934570244362102	0.083355834104444	0.0975305054232194	0.886472661912463	NA	NA	0.13777458114293	0.837175647060909	85.5859507002203
a9827	loss_cnaOV34	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.37776252750879	2.30215642852097	0.0756060989878167	0.977365808470568	1.51616060325436	0.0519312617321016	0.0773570124231468	0.0498668141261103	0.88663408926476	NA	NA	0.821992978532511	0.889117132442311	85.5859507002203
a9828	loss_cnaOV36	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.88252694558041	2.85687248126838	0.0256544643120304	1.60098251010712	1.08809449298927	0.0227119966488635	0.0160242002333392	0.023577423171724	0.886768803209343	NA	NA	0.393573338515842	0.980634343145825	85.5859507002203
a9829	MLL2_mut	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	3.735844173235	4.00508680493457	-0.269242631699565	0.401759874273736	0.782994992440824	0.35263124707052	0.670158094275285	0.34386252057661	0.886936820336972	NA	NA	0.52803641449089	0.383221130042449	85.5859507002203
a9830	loss_cnaOV35	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.37751577623941	2.30220212320049	0.0753136530389167	0.976939024360106	1.51620528102711	0.0517303148036978	0.0770914572567587	0.0496724645279546	0.886956419638913	NA	NA	0.82199333494373	0.889508839718944	85.5859507002203
a9831	gain_cnaOV4_(KRAS)	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	6	13	2.77258872223978	NA	-0.480995258038109	-0.610170621921409	0.1291753638833	0.948322562923569	2.16273565250305	0.0684031067314451	0.136214584502838	0.0597277636468419	0.887012674263428	NA	NA	0.0446661394592914	0.858556582588223	85.5859507002203
a9832	loss_cnaOV33_(ZFHX3)	1016	Temsirolimus	MTOR	4	27	-1.6094379124341	NA	-1.87400926425945	-2.05237256894764	0.178363304688186	0.717695597557887	1.64292482010343	0.11341505513405	0.248522222088452	0.108564495773432	0.887286539349364	NA	NA	0.0389560369702704	0.717971876652681	85.5859507002203
a9833	loss_cnaOV38	256	JW-7-24-1	LCK	8	24	2.32630161961136	NA	2.01674477071792	1.91354401807035	0.103200752647566	1.277811493755	1.3740538942183	0.0763200538907339	0.0807636753558211	0.0751067720719036	0.887372569703054	NA	NA	0.839997061972375	0.849151046270885	85.5859507002203
a9834	loss_cnaOV33_(ZFHX3)	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.47362026641565	4.38900703104835	0.084613235367299	0.983678080997062	0.750484947722052	0.108777356682722	0.0860172011574503	0.112744746745589	0.887408973139618	NA	NA	0.0442999100532597	0.877889492109642	85.5859507002203
a9835	loss_cnaOV81_(RB1)	274	PXD101, Belinostat	HDAC	4	26	2.99573227355399	NA	0.592539054733855	0.895103725451779	-0.302564670717924	1.88596939069722	2.11505368821424	0.144649480389904	0.160429258401733	0.143052950572324	0.887414444466002	NA	NA	0.41892650267895	0.78276363017419	85.5859507002203
a9836	PIK3CA_mut	1378	Bleomycin (50 uM)	DNA damage	6	26	3.91202300542815	NA	1.3512400317969	2.2012866971952	-0.850046665398295	1.72798197705206	2.02034894900756	0.430484121241014	0.491930284393636	0.420742498871721	0.887495792024935	NA	NA	0.134681088885562	0.322445092089217	85.5859507002203
a9837	loss_cnaOV83	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.35562808550326	4.44517467616884	-0.0895465906655781	1.09636992451432	0.672558497951098	0.120493589246978	0.0816755263559843	0.133143200090959	0.887602858273494	NA	NA	0.526819669231515	0.867385641097769	85.5859507002203
a9838	PIK3R1_mut	194	AUY922	HSP90	3	16	-1.36257783450257	NA	-3.02516758831252	-2.4556836239214	-0.569483964391124	0.999962534197497	2.11516470598707	0.282448760711062	0.569505301364269	0.269238590630401	0.887625788385548	NA	NA	0.350236879505434	0.493589782536616	85.5859507002203
a9839	loss_cnaOV57_(ZNRF3)	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-3.21894637780581	-3.32944606866544	0.110499690859633	2.00620775265979	1.81744421515235	0.0601237547589297	0.0550788873750161	0.0607994952133208	0.887705283833266	NA	NA	0.141829186691692	0.922456435217722	85.5859507002203
a9840	loss_cnaOV40	136	Mitomycin C	DNA crosslinker	4	15	2.77258872223978	NA	-0.444007747872917	-0.585071645978517	0.1410638981056	1.408014431905	1.52713858290095	0.0936181242579435	0.100186400727971	0.0923713798374706	0.887763018664584	NA	NA	0.91017957281277	0.867987832762262	85.5859507002203
a9841	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	258	STF-62247	stimulates autophagy	5	26	2.32630161961136	NA	4.54216270222105	4.47935991129585	0.0628027909251978	0.786592082940787	0.663551029634756	0.0921073348292529	0.0798416260311197	0.0946465126574618	0.887946496161072	NA	NA	0.0548142589620627	0.873394965127958	85.5859507002203
a9842	gain_cnaOV94	277	ABT-869	VEGFR and PDGFR family	7	25	0.0237165266173161	NA	2.79942916424287	2.69268574300068	0.106743421242192	0.588326124433656	0.568247796612545	0.186510091306305	0.181435800330892	0.187846608255262	0.887953126893224	NA	NA	0.137865619896012	0.678698772539525	85.5859507002203
a9843	loss_cnaOV39	238	CAL-101	PI3Kdelta	9	23	2.99573227355399	2.32630161961136	4.47061374058485	4.3545905559542	0.116023184630654	0.838647835993222	1.04231711711122	0.116946831515161	0.138345536292056	0.111312749954843	0.887978276971722	NA	NA	0.513988665038934	0.74691168259023	85.5859507002203
a9844	loss_cnaOV1	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.31507223700999	3.27216869399715	0.0429035430128355	0.457029097456209	1.079742976979	0.0408689152738098	0.0938748610353992	0.0397349590852397	0.888013511827903	NA	NA	0.093792939708994	0.902178804523079	85.5859507002203
a9845	loss_cnaOV1	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.75627543362894	4.79908400176032	-0.0428085681313766	1.05632754809477	0.632984106500224	0.0639328376666275	0.0405258465601769	0.0676297677805302	0.888213831758921	NA	NA	0.763471899013147	0.950927015119438	85.5859507002203
a9846	loss_cnaOV16, loss_cnaOV17	1230	IOX2	EGLN1	6	26	-2.30258509299405	NA	-0.0582611437242982	-0.0645460879828485	0.00628494425855022	1.1526351605456	0.93213447531876	0.00646357680621575	0.00545267442264667	0.0067425295651692	0.8882160169016	NA	NA	0.55131813317576	0.990435040639458	85.5859507002203
a9847	loss_cnaOV84	260	NG-25	MAP3K7 (TAK1)	6	26	2.32630161961136	NA	2.89791178109426	3.03830556849552	-0.140393787401265	1.52500381896882	0.97923440981077	0.12887816580491	0.0920612693915723	0.143370970213756	0.888220275563059	NA	NA	0.437255257765729	0.83654427701531	85.5859507002203
a9848	loss_cnaOV52, loss_cnaOV53	163	JQ1	BRD4	5	14	0.940007258491471	NA	0.107559446444855	0.0817081295400166	0.0258513169048386	0.853239127667	2.10824933501966	0.0136815883410201	0.0302978567983907	0.0122619827149608	0.888305687084218	NA	NA	0.586007977882166	0.970154585124081	85.5859507002203
a9849	loss_cnaOV20	1149	TW 37	BCL2, BCL2L1	5	28	1.6094379124341	NA	-0.552565482659304	-0.773932943874269	0.221367461214965	1.21421736406174	0.877120028082426	0.238664319471565	0.182312877221964	0.252379895712702	0.888448834736755	NA	NA	0.0430591183913363	0.713393272594568	85.5872163532304
a9850	loss_cnaOV33_(ZFHX3)	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.54531646513943	2.50589132498957	0.0394251401498571	0.392726396218373	0.655843258204566	0.0621395814354593	0.100388312396336	0.0601136623067335	0.888499229366348	NA	NA	0.858944200866181	0.870980423673178	85.5872163532304
a9851	loss_cnaOV81_(RB1)	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.62176181419749	4.46989347955583	0.151868334641662	0.894721812486465	0.65094648435448	0.223260911519399	0.169738048768046	0.233303871042893	0.888614550295222	NA	NA	0.0548152389342438	0.762407924708762	85.5896356667183
a9852	loss_cnaOV82	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.39484632369702	2.35814498165501	0.0367013420420106	0.542767224865065	0.896943953512605	0.0418110997572604	0.0676189356332906	0.0409182111081535	0.888981547347246	NA	NA	0.610059629257728	0.923650168139923	85.6134487645222
a9853	gain_cnaOV19	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	1.64551073842603	1.51921213623943	0.126298602186595	0.905185732178819	1.98751493014418	0.0652944300307774	0.139527831357426	0.0635459891500954	0.889075549927827	NA	NA	0.783866747001204	0.852272595624207	85.6134487645222
a9854	loss_cnaOV55	1268	XAV 939	TNKS1 (tankyrase-1)	7	25	1.6094379124341	NA	2.82032217714872	2.86581400231579	-0.0454918251670735	0.934267506089615	1.11477672216032	0.0420796401114516	0.0486925049523342	0.0408080149708501	0.889141758870163	NA	NA	0.3096640156202	0.915168430654672	85.6134487645222
a9855	loss_cnaOV41	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.17922744513527	4.30396883762366	-0.12474139248839	0.538486575611237	0.861661606017113	0.151265829820278	0.231651814804845	0.144768423726091	0.889222706720979	NA	NA	0.319825756688328	0.681993513498149	85.6134487645222
a9856	loss_cnaOV54	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	21	2.30258509299405	NA	2.07796013953416	2.20905539854116	-0.131095259007002	1.87352754811509	0.956439923372742	0.0999526897424332	0.0699724213497119	0.137065858297418	0.889587347527282	NA	NA	0.688366572871594	0.83839813282361	85.6311431117866
a9857	PIK3CA_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	1.22275217195766	1.61419722251603	-0.391445050558365	0.783833574326061	1.10204380191925	0.363863833809174	0.499398167391501	0.355199176182153	0.889734197049018	NA	NA	0.457991825696938	0.497629540787594	85.6311431117866
a9858	gain_cnaOV18_(CCNE1)	172	Embelin	XIAP	4	15	3.46573590279973	NA	3.00331219695869	3.12322715096584	-0.119914954007157	0.515487862032726	1.04048882292909	0.1237842664478	0.232624204834418	0.115248670975228	0.889749654695422	NA	NA	0.674274498662006	0.753749248064276	85.6311431117866
a9859	loss_cnaOV36	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.20639500701655	3.99356787693349	0.212827130083057	0.440749372182634	1.08759721239582	0.201376170529772	0.482875628453231	0.195685615646467	0.889767485826634	NA	NA	0.106691252221725	0.540439977292995	85.6311431117866
a9860	loss_cnaOV84	308	XL-880	MET	6	26	1.63315443905142	NA	0.243105150187508	0.255404535444026	-0.0122993852565175	0.471847823086457	1.05163865756599	0.0125613412166519	0.0260664236534242	0.0116954480210764	0.889937493876948	NA	NA	0.371126028206445	0.965710985093362	85.6319763826143
a9861	loss_cnaOV39	1248	FK866	NAMPT	9	23	0	NA	-1.38993504818011	-1.8329579366075	0.443022888427392	3.61352146700286	2.39511927217711	0.159770114681613	0.122601427021505	0.184969029965967	0.889988188050682	NA	NA	0.0457806885947305	0.740513083309344	85.6319763826143
a9862	gain_cnaOV4_(KRAS)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.56149569905701	1.56348516684029	-0.00198946778327369	0.808378948011102	1.12406964495179	0.00183426796014056	0.00246105837883147	0.00176987946628432	0.890046894517713	NA	NA	0.457993070723138	0.99682868499375	85.6319763826143
a9863	NF1_mut	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	5.07426674443638	4.94280947674882	0.131457267687566	0.373778339497978	0.868029631129757	0.1576832078349	0.351698463490758	0.151443295220777	0.890165453289704	NA	NA	0.457969170503565	0.666217958680054	85.6346996977804
a9864	loss_cnaOV34	1009	ATRA	Retinoic acid and retinoid X receptor agonist	5	26	2.30258509299405	NA	4.41222141100075	4.53078852507904	-0.11856711407829	1.58275112149376	0.774280668083257	0.127679833228447	0.0749120392133344	0.153131957138752	0.890337341085491	NA	NA	0.530969218603855	0.877194240783484	85.6398287762066
a9865	PIK3CA_mut	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	2.6704961972226	2.72271367808691	-0.0522174808643072	0.615324197875073	1.50571140568011	0.0386763921774942	0.0848617379986553	0.0346796077039219	0.890399286460261	NA	NA	0.941768218341797	0.916002986638501	85.6398287762066
a9866	ARID1A_mut	1042	BIRB 0796	p38, JNK2	9	24	2.30258509299405	NA	4.45112928504495	4.37738704448254	0.0737422405624049	0.539955675044807	0.954722269802563	0.0850646470136582	0.136570914929796	0.0772394683719432	0.890568560683142	NA	NA	0.870269490701501	0.783266557090154	85.6474278548272
a9867	ARID1A_mut	309	Y-39983	ROCK	8	24	2.99573227355399	NA	4.69846340497797	5.05289832661456	-0.354434921636596	0.892283688061231	1.32469490536788	0.286437667040278	0.397222235908759	0.267559662379895	0.890865531738683	NA	NA	0.375424993295998	0.404791564076028	85.6673049607309
a9868	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	300	CX-5461	RNA Pol I	7	24	2.32630161961136	NA	3.61472008867286	3.5174311438976	0.0972889447752605	1.77020343906285	1.71037273208129	0.0564674119418311	0.0549591886606917	0.0568817211303838	0.891058970196832	NA	NA	0.700309766480722	0.900106795626535	85.677223157666
a9869	loss_cnaOV54	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	10	22	2.30258509299405	NA	0.932534516394328	0.84048816606425	0.0920463503300778	1.18666424246814	1.28434438378083	0.0732947441254606	0.0775673076140148	0.07166796654579	0.891169995545497	NA	NA	0.845810907731598	0.845052830707364	85.6792159510699
a9870	PIK3CA_mut	1005	Cisplatin	DNA crosslinker	7	24	1.79175946922805	2.30258509299405	2.57314509011711	3.15494182220157	-0.581796732084455	1.41105465889905	1.10655390615718	0.494708071370282	0.41231339155805	0.525773510759098	0.891286670560648	NA	NA	0.0904536915221143	0.343598571567774	85.6817514580886
a9871	loss_cnaOV52, loss_cnaOV53	301	PHA-793887	CDK-pan	8	24	2.32630161961136	NA	2.99002862259711	3.01644313216159	-0.0264145095644794	0.978095987517352	1.78889821937611	0.0161452423719423	0.0270060504302098	0.0147657978963675	0.891426359812289	NA	NA	0.665343766822182	0.95857127840381	85.6864986468363
a9872	gain_cnaOV51_(MYC)	1259	BMN-673	PARP1	8	25	2.30258509299405	NA	2.0592703791883	1.84956840741303	0.209701971775265	1.03275290341537	1.47535721924812	0.151103011922665	0.203051447332434	0.142136405366379	0.891621220661915	NA	NA	0.0352445147865428	0.660732450501958	85.6965475913608
a9873	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.19255702848206	1.36172601075448	-0.169168982272422	2.34227325583279	1.19859281916907	0.12418933550036	0.0722242726595425	0.141139659413027	0.891897885109075	NA	NA	0.583188199893499	0.895664376044567	85.7138669539434
a9874	loss_cnaOV82	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-2.00224607338921	-1.98855844117187	-0.0136876322173412	2.69229069423491	1.99786104313768	0.00667762749565466	0.00508400977897777	0.00685114325861445	0.892063783999994	NA	NA	0.281056701686712	0.993867272602675	85.7138669539434
a9875	loss_cnaOV44	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.03198630008875	4.03276268524666	-0.000776385157905679	1.48111901606363	1.51199222341325	0.00051417813961191	0.000524188231658166	0.000513484888270804	0.892094466479947	NA	NA	0.332603088499484	0.999376929883166	85.7138669539434
a9876	loss_cnaOV57_(ZNRF3)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.53395902339435	3.48304076558677	0.0509182578075844	0.52664857951632	1.17272768756365	0.0453308197014773	0.0966835567169824	0.0434186540895673	0.892162764043734	NA	NA	0.728426151970946	0.88669856393794	85.7138669539434
a9877	MLL2_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	2.50802496250447	1.66076480411262	0.84726015839185	1.42211147511479	1.71352905453075	0.499493255888651	0.595776191401213	0.494453336610549	0.892459895644611	NA	NA	0.231916372229418	0.415268029501368	85.730879627052
a9878	PIK3CA_mut	1033	Vismodegib	SMO	7	24	2.30258509299405	NA	4.69372870604289	4.97429758737062	-0.280568881327728	0.729000736570699	0.889668641919073	0.326662065455131	0.384867761104817	0.315363347776901	0.892561425751319	NA	NA	0.156718617221902	0.412176320805213	85.730879627052
a9879	loss_cnaOV34	302	PI-103	PI3Ka, PRKDC (DNAPK)	5	27	2.32630161961136	NA	1.56392554058997	1.23914607659527	0.324779463994697	2.37482911012106	2.33841274432348	0.138599125663833	0.13675908831105	0.138888853040638	0.892623650810689	NA	NA	0.366323201943862	0.788497210132638	85.730879627052
a9880	loss_cnaOV59	1054	PD-0332991	CDK4, CDK6	4	29	1.38629436111989	0.693147180559945	2.60625558562192	2.23972937377782	0.366526211844105	2.35996564598681	1.73040498642333	0.203515522997542	0.155309977697088	0.211815277186469	0.892701259946757	NA	NA	0.112542328891834	0.781526768779213	85.730879627052
a9881	MLL2_mut	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.46615753172525	2.28050196973886	0.185655561986384	0.289789748165966	1.30974470325781	0.146639990081173	0.640656072760919	0.141749427598058	0.892965293456447	NA	NA	0.845472010524216	0.543647951936138	85.7475572755063
a9882	ARID1A_mut	1218	JQ1	BRD2, BRD3, BRD4	9	22	0	NA	2.36326942070225	2.26564207420012	0.0976273465021289	0.462982377313459	1.02697357923818	0.107623731852931	0.210866225770038	0.0950631530117357	0.893196552547213	NA	NA	0.596684932239453	0.718206108284107	85.7486719699133
a9883	loss_cnaOV39	1239	YK 4-279	RNA helicase A	6	18	2.30258509299405	NA	1.73867970982726	1.51311896513551	0.225560744691748	0.742672683608606	1.13954677099167	0.212303098091192	0.303714879609899	0.197938996830694	0.89353953017867	NA	NA	0.290917243437017	0.586744257868468	85.7486719699133
a9884	loss_cnaOV54	1371	PLX4720 (rescreen)	BRAF	11	22	2.30258509299405	NA	4.63267595387621	4.47607656044266	0.15659939343355	1.05231899652588	0.96392222595977	0.157656128982089	0.148813614455831	0.162460610634457	0.893557893863907	NA	NA	0.328281646198145	0.683427783149636	85.7486719699133
a9885	loss_cnaOV83	197	Bryostatin 1	PRKC	4	15	-4.8283137373023	NA	-2.25343033435353	-2.34559554119107	0.0921652068375387	1.07581340288662	0.680177403121839	0.12047571964194	0.0856702534010465	0.135501718249569	0.893636690892116	NA	NA	0.677623364443629	0.879194750038692	85.7486719699133
a9886	loss_cnaOV54	299	OSI-027	MTORC1/2	10	22	2.99573227355399	NA	1.56188929229275	1.51703596560428	0.0448533266884712	1.76147152451561	2.00415352270632	0.0231854279979787	0.0254635547973479	0.0223801850408661	0.893654002025017	NA	NA	0.783872588507421	0.949698898653361	85.7486719699133
a9887	loss_cnaOV40	170	Shikonin	unknown	3	15	2.77258872223978	NA	-0.107131985893139	0.00788915602983726	-0.115021141922977	0.684037750133009	0.817078167006783	0.143479340965281	0.168150283958175	0.140771283051578	0.893655584431319	NA	NA	0.5885478142969	0.81260803476864	85.7486719699133
a9888	loss_cnaOV57_(ZNRF3)	1003	Camptothecin	TOP1	4	27	-2.30258509299405	NA	-3.63768696322892	-3.69909100856963	0.061404045340717	2.69287634297367	1.59801534091353	0.0352196872352475	0.022802400675001	0.038425191403741	0.893692836644276	NA	NA	0.24806318164952	0.967079159021519	85.7486719699133
a9889	gain_cnaOV4_(KRAS)	1004	Vinblastine	Microtubules	5	26	-2.30258509299405	NA	-3.46576701099864	-3.28623055039219	-0.179536460606454	2.12987988981121	1.78568879975189	0.0977334292886894	0.0842941714531934	0.100541852886908	0.893715515335931	NA	NA	0.141843746408668	0.866340763420982	85.7486719699133
a9890	loss_cnaOV83	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.83818592651934	4.80687251593544	0.0313134105839037	0.580936012541178	0.77645369568593	0.0415670819779375	0.0539016516585535	0.0403287546416287	0.893842777248827	NA	NA	0.766577673444942	0.919733442181265	85.7486719699133
a9891	gain_cnaOV26	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-4.6624466302737	-4.652531553943	-0.00991507633070299	1.31790006504907	2.16977861691747	0.00474933156577372	0.0075233901216431	0.00456962579195707	0.893930811768894	NA	NA	0.354908299906111	0.991998269131719	85.7486719699133
a9892	SMARCA4_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.30363183414994	1.34378338935176	-0.0401515552018201	0.118949039775267	1.41261526820035	0.0294497472999554	0.337552579471675	0.0284235602613672	0.893971929216306	NA	NA	0.583193007968493	0.885197653656082	85.7486719699133
a9893	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.50291855681126	4.39944993404332	0.103468622767938	0.757565590761993	0.626909053814443	0.162570335598818	0.136580414989367	0.165045666733286	0.894061379322154	NA	NA	0.273972346122271	0.837981468077385	85.7486719699133
a9894	gain_cnaOV26	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.636110379833331	0.839118502480131	-0.2030081226468	0.521119746184317	1.14653244030913	0.187243576388669	0.389561370746825	0.177062694006342	0.894564666628319	NA	NA	0.361196318630995	0.650550928139242	85.7816680815726
a9895	loss_cnaOV20	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.3860371906314	3.2171512762913	0.168885914340097	1.35382864673661	0.9704102635299	0.162329911788987	0.124746890787984	0.174035581328014	0.894674078033202	NA	NA	0.569255534978145	0.825976922160515	85.7816680815726
a9896	TP53_mut	200	LAQ824	HDAC	12	7	0.0237165266173161	NA	-2.73627458642016	-2.76610603280603	0.0298314463858684	1.24111791274169	1.24746762566358	0.0239925539103525	0.0240359486231	0.0239136036656661	0.894676638095543	NA	NA	0.38400380177037	0.960610769763329	85.7816680815726
a9897	loss_cnaOV82	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.17208127362153	5.05061734045459	0.121463933166938	0.746648052293455	0.611677677672962	0.19540902260593	0.162678966072222	0.198575062652326	0.895344152052758	NA	NA	0.112644605691912	0.807933289358347	85.8179927609036
a9898	loss_cnaOV43_(NF1)	1067	CCT007093	PPM1D	5	28	1.88706964903238	NA	4.61625857863763	4.46713325364935	0.149125324988274	1.14333906428677	0.612264982349141	0.211920609964708	0.130429659622713	0.24356337417193	0.895394935800513	NA	NA	0.0831573559112446	0.788901101098432	85.8179927609036
a9899	PIK3R1_mut	1058	GDC0941	PI3K (class 1)	5	28	1.38629436111989	0.693147180559945	0.684824537096066	0.872272261369975	-0.187447724273909	1.64749482419747	1.30581209496316	0.138363206352378	0.113777428323769	0.143548773209363	0.895425662945619	NA	NA	0.165694755533853	0.819062869988762	85.8179927609036
a9900	loss_cnaOV33_(ZFHX3)	1025	SB 216763	GSK3A, GSK3B	3	20	2.30258509299405	NA	4.95179664603219	4.96117999150945	-0.00938334547725361	1.40828000728528	0.749519141358044	0.0112380844284759	0.00666298280790177	0.0125191538941248	0.895523499127367	NA	NA	0.457989917911434	0.99193464650524	85.8179927609036
a9901	ARID1A_mut	273	CUDC-101	HDAC, EGFR	8	23	1.63315443905142	NA	0.411401608153326	0.0160470521995549	0.395354555953771	1.50788154326289	1.66331734794889	0.242972385586333	0.262192051968663	0.237690394103868	0.895772757435352	NA	NA	0.464648204693785	0.544610131152751	85.8179927609036
a9902	gain_cnaOV51_(MYC)	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.4129579184735	3.51196797229607	-0.0990100538225653	0.931326361737465	1.16733282061472	0.088198494193316	0.106310803484456	0.0848173306481923	0.89585552241646	NA	NA	0.728432038855713	0.819714892594567	85.8179927609036
a9903	gain_cnaOV95_(MECOM)	341	EX-527	SIRT1	8	23	2.99573227355399	NA	5.75302287266748	5.78037076801063	-0.0273478953431416	0.67650935370699	0.530578622958942	0.0480429127729185	0.0404250069763065	0.0515435303266222	0.895919602497146	NA	NA	0.112805572669274	0.919366028068902	85.8179927609036
a9904	loss_cnaOV35	301	PHA-793887	CDK-pan	5	27	2.32630161961136	NA	3.14663968053048	2.98450613888899	0.162133541641491	1.23465536121919	1.6881498869172	0.0991661953788164	0.131318865761363	0.0960421482108849	0.896277629827318	NA	NA	0.665352762860716	0.807361161641974	85.8179927609036
a9905	PIK3R1_mut	140	Vinorelbine	Microtubules	3	16	-2.74887219562247	NA	-3.2050546205447	-3.50365034351361	0.298595722968904	1.97330622132184	1.76280090364347	0.166920267269479	0.151317479133516	0.16938709434046	0.896395703695986	NA	NA	0.684642510223647	0.824659542553727	85.8179927609036
a9906	gain_cnaOV94	1024	CEP-701	FLT3, JAK2, NTRK1, RET	7	24	0.693147180559945	NA	0.117788692325226	-0.238150831813049	0.355939524138276	1.83224305356192	1.55309227213425	0.220421692146096	0.194264359985605	0.229181182937151	0.896669615598712	NA	NA	0.102613954682697	0.651771202620376	85.8179927609036
a9907	loss_cnaOV33_(ZFHX3)	1373	Dabrafenib	BRAF	4	28	2.30258509299405	NA	3.81671912177972	3.62194893658436	0.194770185195367	1.43081370269135	2.09989042418582	0.0953415541635842	0.136125468206662	0.0927525469672468	0.896823746394833	NA	NA	0.748875437775045	0.821133430144726	85.8179927609036
a9908	gain_cnaOV96	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-4.02179930416109	-4.17105891552389	0.149259611362802	1.37244514322864	2.45880457365245	0.0630749417537186	0.108754518968731	0.0607041376782065	0.896872670067127	NA	NA	0.928508498842066	0.864166126598527	85.8179927609036
a9909	loss_cnaOV70	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.67130457514862	-2.06772081047065	0.396416235322027	0.953688815785318	1.6054362137404	0.252622681015847	0.415666230703982	0.246921199315943	0.896908600350201	NA	NA	0.0389669116494461	0.568454476518713	85.8179927609036
a9910	loss_cnaOV41	219	AT-7519	CDK9	5	27	2.32630161961136	NA	1.52309937659878	1.4930055448503	0.030093831748482	1.08285875467886	1.7966809246205	0.0175094440768468	0.0277910961318376	0.016749680667333	0.896939825243245	NA	NA	0.318993619545507	0.960798126973578	85.8179927609036
a9911	loss_cnaOV57_(ZNRF3)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-2.2782217106813	-1.95002084871029	-0.328200861971013	3.01254594263636	1.9146469877727	0.160348498392351	0.108944682743592	0.171415861026584	0.896952853867063	NA	NA	0.281069808350414	0.844343725096415	85.8179927609036
a9912	RB1_mut	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.32185659292928	4.40828932589929	-0.086432732970005	0.758079342367831	0.779413779221057	0.11110159541864	0.11401541783217	0.110894540582007	0.897011169139005	NA	NA	0.0443117298442631	0.865781087651258	85.8179927609036
a9913	loss_cnaOV1	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	4.0725748540715	3.97025259657217	0.102322257499335	0.793166480246503	0.765307826148052	0.133371635295416	0.129004767659288	0.133700785492216	0.897088544090393	NA	NA	0.528061472718744	0.847793191116264	85.8179927609036
a9914	ARID1A_mut	1026	17-AAG	HSP90	9	24	0	NA	-1.3128046655272	-0.237592468076117	-1.07521219745108	2.1945832963265	2.28533472005123	0.475281582390937	0.489939114751704	0.470483464858479	0.897200139789883	NA	NA	0.0627224443435979	0.234321992525389	85.8179927609036
a9915	loss_cnaOV33_(ZFHX3)	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.0410893888625	-1.20609882520848	0.165009436345975	1.30191489878979	1.34961539571763	0.122875008737371	0.126743642383509	0.122264044163659	0.897318177452694	NA	NA	0.0511170988563304	0.82902933930907	85.8179927609036
a9916	SMARCA4_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.38629436111989	0.693147180559945	2.71239891200395	2.83047265489535	-0.118073742891406	0.783094713959512	1.6127872979775	0.0750854488349838	0.150778367912098	0.0732109826506421	0.897467479611388	NA	NA	0.968993317136521	0.837472276058865	85.8179927609036
a9917	loss_cnaOV85	179	5-Fluorouracil	DNA antimetabolite	7	24	3.46573590279973	NA	4.14775130896287	3.83107787173791	0.316673437224963	2.05330119560437	1.62730291612676	0.183674835499797	0.154226490445184	0.194600178053326	0.897492304110029	NA	NA	0.149733474024346	0.716940756558877	85.8179927609036
a9918	loss_cnaOV85	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	2.7514782863165	2.35932844946113	0.392149836855365	1.70177649755927	1.56308413469405	0.246357827005764	0.230435569781223	0.250882104265055	0.897731453420778	NA	NA	0.231637904136364	0.660538883922311	85.8179927609036
a9919	loss_cnaOV54	1527	GDC0941 (rescreen)	PI3K	10	21	1.38629436111989	NA	0.403953630130008	0.371961081110677	0.0319925490193311	0.75348898586295	0.984180761828772	0.0348196877698557	0.0424592125692334	0.0325067815386714	0.897813013348581	NA	NA	0.910216023303582	0.921427472875644	85.8179927609036
a9920	loss_cnaOV20	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.20078151489235	5.18895080389622	0.0118307109961311	0.502580598640155	0.811787920156106	0.0152125105689451	0.0235399277810201	0.0145736475037175	0.897890623746391	NA	NA	0.336488501023269	0.966524016088608	85.8179927609036
a9921	gain_cnaOV4_(KRAS)	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.18353721581906	3.26479832918832	-0.0812611133692651	1.53127533612898	0.922030941117492	0.0779721959925434	0.0530676041414542	0.0881327401776534	0.89802435101655	NA	NA	0.569267593597434	0.924373818276561	85.8179927609036
a9922	gain_cnaOV50	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.17681950153498	4.29970551843524	-0.122886016900261	1.13107318286993	0.781912180953656	0.148968191091971	0.108645504783746	0.15716089337601	0.898065458477693	NA	NA	0.319851594874059	0.845522419066697	85.8179927609036
a9923	loss_cnaOV59	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.39602245401022	3.22486961652484	0.171152837485377	1.66299427913184	0.940951525474498	0.164440752965711	0.102918476409147	0.181893363102917	0.898159557193731	NA	NA	0.569268071874185	0.876688830087942	85.8179927609036
a9924	RB1_mut	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.28977484015456	4.45726229071455	-0.167487450559991	1.49924818482381	0.97457782208869	0.164747405889983	0.111714292707097	0.171856414915165	0.898193561815706	NA	NA	0.377686685879583	0.865926564370133	85.8179927609036
a9925	gain_cnaOV94	282	EKB-569	EGFR	7	25	0.916290731874155	2.99573227355399	1.84597806955791	1.63814468059228	0.20783338896563	1.20309358576803	1.55793840751384	0.139137336129727	0.172749145556249	0.133402827713382	0.898263337450886	NA	NA	0.329316579636743	0.712585733544718	85.8179927609036
a9926	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	308	XL-880	MET	5	27	1.63315443905142	NA	0.142218938598332	0.273631634432521	-0.131412695834189	0.661928909276566	1.01786128700327	0.134380140690728	0.198529923670824	0.129106684292009	0.898328617703524	NA	NA	0.371149396136089	0.720796391583459	85.8179927609036
a9927	gain_cnaOV4_(KRAS)	1022	AZD7762	CHEK1, CHEK2	5	26	0.693147180559945	NA	-0.883545119538294	-0.802336994083938	-0.0812081254543566	0.68413014342258	0.831595723102335	0.0999057027075833	0.118702744258698	0.0976533707405362	0.898388607468305	NA	NA	0.080544372883016	0.822000353546883	85.8179927609036
a9928	loss_cnaOV36	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.27328392865906	4.13876582637787	0.134518102281197	1.76833744151071	0.966899311514076	0.129661102419521	0.0760703806431176	0.139123175163455	0.898513627929302	NA	NA	0.532074263992188	0.907973909370672	85.8179927609036
a9929	loss_cnaOV43_(NF1)	1023	GW 441756	NTRK1	5	26	0.693147180559945	NA	2.3451090908523	2.28949931898471	0.0556097718675983	1.7414209028574	1.17362413103749	0.0438854122641547	0.0319335617117902	0.0473829485922713	0.898585714399363	NA	NA	0.845477170163737	0.94820889700913	85.8179927609036
a9930	PIK3CA_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	2.30258509299405	NA	2.2293973407735	2.14849930747048	0.0808980333030149	1.01690554973589	1.37939603297185	0.0616301705547399	0.079553143675955	0.0586474307372942	0.898591605277562	NA	NA	0.688382798398248	0.867752759542663	85.8179927609036
a9931	gain_cnaOV18_(CCNE1)	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.41765038755962	4.31989447146796	0.0977559160916641	0.993740734257137	0.550265438222211	0.165234183589562	0.0983716503930382	0.177652291605834	0.898647626354777	NA	NA	0.256940944286478	0.881414772090916	85.8179927609036
a9932	loss_cnaOV16, loss_cnaOV17	276	CAY10603	HDAC6	6	25	2.99573227355399	NA	1.2846196565981	1.46884719737831	-0.184227540780218	1.30493293949645	1.89133485906776	0.102128337271399	0.14117778408698	0.097406093847931	0.898652334392999	NA	NA	0.616845612648457	0.783328019443751	85.8179927609036
a9933	gain_cnaOV50	303	PIK-93	PI4K, PI3K	4	28	2.99573227355399	NA	2.72991234547998	2.93038158609329	-0.200469240613312	0.625064189240352	1.30759330086909	0.159591325363374	0.320717846365419	0.153311614918851	0.898736866652156	NA	NA	0.23436143669503	0.629119178274802	85.8179927609036
a9934	gain_cnaOV50	258	STF-62247	stimulates autophagy	4	27	2.32630161961136	NA	4.54095560834241	4.48186476931214	0.0590908390302767	0.33090181577554	0.711398812596473	0.0866492822184398	0.1785751428767	0.0830628867858328	0.898745520744351	NA	NA	0.0548293658509987	0.790100646154723	85.8179927609036
a9935	gain_cnaOV26	157	JNK-9L	JNK	3	16	1.63315443905142	NA	-0.0700315754147623	-0.0242747891379387	-0.0457567862768236	1.75334765281626	0.877867508872638	0.0448324467833296	0.026096813260809	0.052122656111951	0.898778829454904	NA	NA	0.195177817407868	0.968464253412242	85.8179927609036
a9936	loss_cnaOV41	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	5	28	0.693147180559945	NA	2.85220262612677	2.78816330692601	0.0640393192007549	1.51012702377194	0.861291533134984	0.0660388717602482	0.042406577852504	0.0743526631077638	0.898779658889955	NA	NA	0.966390987362789	0.930532771452424	85.8179927609036
a9937	gain_cnaOV50	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.541967301817	4.52638795224513	0.0155793495718708	0.882395348426415	1.00763053259793	0.0156387878180085	0.0176557476188577	0.0154613710758677	0.89882573634326	NA	NA	0.328295661684975	0.975566053170124	85.8179927609036
a9938	loss_cnaOV16, loss_cnaOV17	1502	Bicalutamide	ANDR (androgen receptor)	5	27	2.30258509299405	NA	4.50802160890067	4.51767578258466	-0.00965417368399368	0.509977301552203	0.617294610616458	0.0159813980430888	0.0189305948610057	0.0156394912865878	0.898866473978228	NA	NA	0.61718099050785	0.971197752233635	85.8179927609036
a9939	loss_cnaOV41	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.56535625708483	3.54048682373995	0.0248694333448864	0.929845734822621	0.908705293099705	0.0272825070761879	0.0267457626717303	0.0273679855655443	0.898944679581144	NA	NA	0.665177711671719	0.957978704205631	85.8179927609036
a9940	loss_cnaOV36	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	2.6762432759053	2.52312472909007	0.153118546815232	1.23417961671472	1.02817802045968	0.146848506575325	0.124065042674113	0.148922213632593	0.899125224182918	NA	NA	0.397864317616694	0.852456150623222	85.8265931644386
a9941	loss_cnaOV70	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.557448810622291	0.566590869762007	-0.00914205913971577	1.53480669922604	1.19633137503264	0.00747702686544541	0.00595648894699628	0.00764174486309562	0.899416514213701	NA	NA	0.433777781201429	0.992834918492329	85.8376287089362
a9942	PIK3R1_mut	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.485696235763081	-0.568438560867511	0.0827423251044301	1.26106743846676	1.53758699258775	0.0548802023819051	0.0656129264625453	0.0538131016347733	0.899440529992552	NA	NA	0.910190958674713	0.925854504030258	85.8376287089362
a9943	loss_cnaOV83	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	5	26	2.32630161961136	NA	2.15711454408476	2.32011685557916	-0.163002311494405	0.527739677259884	1.51661436585212	0.114651809264671	0.308868782314684	0.107477757803528	0.899587352683563	NA	NA	0.532486465685591	0.672511903378396	85.8376287089362
a9944	loss_cnaOV39	299	OSI-027	MTORC1/2	9	23	2.99573227355399	NA	1.56337275201725	1.51840562600289	0.0449671260143614	2.23599575006014	1.81255257988676	0.023244174997173	0.0201105596972408	0.024808729144382	0.899602700835783	NA	NA	0.783879801824589	0.95794823688203	85.8376287089362
a9945	loss_cnaOV1	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	3	20	2.30258509299405	NA	1.5556642736651	1.56426040725991	-0.00859613359480793	1.02406083170046	1.09078520511403	0.00792557180899215	0.00839416305038637	0.00788068407465182	0.899716676483622	NA	NA	0.4580297848539	0.990197215347079	85.8398716252542
a9946	loss_cnaOV87, loss_cnaOV88	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.49514022251101	1.49797330780755	-0.00283308529653592	1.34522033976971	1.74237642126	0.0016483339774398	0.00210603810601088	0.00162598923055167	0.899879098221873	NA	NA	0.319001531551423	0.997542574798775	85.8467357544305
a9947	loss_cnaOV41	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.4979756905917	1.78061216278334	-0.282636472191648	1.8458278110382	1.69076606144198	0.165133491659108	0.153121797440399	0.167164741851158	0.900254166755242	NA	NA	0.231936195558427	0.761764973477596	85.8578111729697
a9948	loss_cnaOV81_(RB1)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	4	29	0.693147180559945	NA	1.68461518210307	1.74512269939586	-0.0605075172927874	1.60191050925343	1.72627412202779	0.0352888986643762	0.0377720958463447	0.035050932248067	0.900294753151139	NA	NA	0.23193629479675	0.947430662689647	85.8578111729697
a9949	loss_cnaOV38	346	THZ-2-102-1	CDK7	8	24	0.916290731874155	2.99573227355399	-1.08712116979116	-1.05018390174035	-0.0369372680508055	2.42045509420357	1.83838272587546	0.0185661931243719	0.0152604640917577	0.0200922623624064	0.900332780399063	NA	NA	0.446321602267117	0.969258694301324	85.8578111729697
a9950	PIK3R1_mut	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.26950483018033	2.30275957137565	-0.033254741195325	0.372669446113893	1.33239944213804	0.0262409852238006	0.0892338815057081	0.0249585373151783	0.900567664474558	NA	NA	0.845478921775411	0.917619762737089	85.8578111729697
a9951	loss_cnaOV87, loss_cnaOV88	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.02968271647831	3.0101505971729	0.0195321193054108	1.92959444923062	1.0044377524427	0.0179061340370935	0.010122396088566	0.0194458235544319	0.900576347562841	NA	NA	0.437288258370426	0.987698490867002	85.8578111729697
a9952	BRCA1_mut	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	2.97009052959045	2.8395443992705	0.130546130319951	0.808598114900151	1.10642505493615	0.120837625159429	0.161447482889657	0.117989130612633	0.900688116528333	NA	NA	0.30969616167553	0.786269314353777	85.8578111729697
a9953	loss_cnaOV87, loss_cnaOV88	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.72630895359097	8.75207537687709	-0.0257664232861217	0.667393323000558	1.27806351230776	0.020685995141925	0.0386075532944763	0.0201605186581034	0.900842542177117	NA	NA	0.532489190310455	0.95764391452137	85.8578111729697
a9954	loss_cnaOV39	164	JQ12	HDAC	5	14	1.63315443905142	NA	1.82307407586946	1.78347126517836	0.0396028106911002	2.90437269676968	1.99734485193579	0.0176483696012095	0.0136355815268294	0.0198277281225211	0.900895505889655	NA	NA	0.663871534330924	0.978511294594073	85.8578111729697
a9955	loss_cnaOV70	1007	Docetaxel	Microtubules	3	28	-4.38202663467388	NA	-4.57558729912554	-4.65639509472892	0.080807795603385	1.24773557676661	1.44563076556995	0.0563961334461796	0.0647635581673411	0.0558979495511264	0.90091970257299	NA	NA	0.137808166853099	0.923988321084073	85.8578111729697
a9956	loss_cnaOV70	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.25494373433957	4.28031919719243	-0.0253754628528577	0.307903946128434	0.93127209386066	0.0280950660566335	0.0824135681660703	0.0272481727092904	0.901221094020218	NA	NA	0.524054764288483	0.921326374972947	85.8578111729697
a9957	KRAS_mut	283	GSK2126458	PI3K, MTOR	7	25	-2.05572501506252	0.0237165266173161	-2.8661327440649	-2.69467702816491	-0.171455715899997	0.891346676542898	1.94160850548268	0.0962266830840858	0.192355814423396	0.0883060181369433	0.901272965213177	NA	NA	0.69801262839228	0.741827686903	85.8578111729697
a9958	PIK3CA_mut	151	QS11	ARFGAP	5	14	2.32630161961136	NA	3.12128085026383	3.99731469991242	-0.876033849648587	1.40423754305108	1.42623478563967	0.616452228867726	0.623850184025968	0.614228357398873	0.901352325443547	NA	NA	0.0673315255535794	0.270933016345753	85.8578111729697
a9959	loss_cnaOV41	1241	CHIR-99021	GSK3B	5	27	2.30258509299405	NA	3.64457674512518	3.68828054824209	-0.0437038031169052	1.09999332653133	1.05549540960712	0.0411703353744208	0.039730971145724	0.0414059622799999	0.901367172157651	NA	NA	0.831990625379056	0.937483064460208	85.8578111729697
a9960	loss_cnaOV35	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	1.83571548060274	1.5152098473532	0.320505633249539	1.17045427965275	1.68990924468711	0.196600270897113	0.273830117776685	0.189658488618353	0.901399766525694	NA	NA	0.0805566606853133	0.617973061186632	85.8578111729697
a9961	loss_cnaOV52, loss_cnaOV53	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.03814180914953	-1.20671936830595	0.168577559156414	0.54746536196373	1.43310405222032	0.125538546250817	0.30792369868248	0.117631067259377	0.901443005584471	NA	NA	0.0511242302679967	0.699797742483388	85.8578111729697
a9962	loss_cnaOV55	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-1.03814180914953	-1.20671936830595	0.168577559156414	0.54746536196373	1.43310405222032	0.125538546250817	0.30792369868248	0.117631067259377	0.901443005584471	NA	NA	0.0511242302679967	0.699797742483388	85.8578111729697
a9963	loss_cnaOV57_(ZNRF3)	229	LY317615	PRKCB (PKCbeta)	4	28	2.99573227355399	2.32630161961136	2.9598598295391	2.71889861166688	0.240961217872217	0.929257510376226	1.75622824260118	0.142427196347905	0.259305106691749	0.137203816694876	0.901984160957998	NA	NA	0.324199443407336	0.686328758338074	85.8951075690255
a9964	loss_cnaOV87, loss_cnaOV88	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.39176546058685	2.30592206296033	0.0858433976265114	1.00914046856911	1.48270559794654	0.0589610225807369	0.0850658558448572	0.0578964547954761	0.902015644863246	NA	NA	0.822008827810604	0.902505020454048	85.8951075690255
a9965	PTEN_mut	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	0.669828875490911	1.40132910847043	-0.731500232979522	1.75257367425449	1.12456740557776	0.608456789079214	0.417386295209922	0.650472554469694	0.902114253229871	NA	NA	0.09945955758995	0.470711312432224	85.8958770018007
a9966	KRAS_mut	274	PXD101, Belinostat	HDAC	6	24	2.99573227355399	NA	0.949307896079154	0.831125237675281	0.118182658403873	2.56239821342365	1.9773482050189	0.0564428817028829	0.0461218938511384	0.0597682583694171	0.902237122433337	NA	NA	0.418969458502038	0.919203431177702	85.8983696497367
a9967	loss_cnaOV34	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-1.02805754646076	-1.21888597233929	0.190828425878534	1.12786787672583	1.38755794976787	0.142199877632958	0.169193954200117	0.137528256683231	0.90256796891163	NA	NA	0.0511261235358025	0.759295008560528	85.8983696497367
a9968	gain_cnaOV72_(ASXL1)	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	4	15	-0.669430653942629	NA	-3.97259726439048	-3.98508948102792	0.0124922166374413	1.66936289786488	1.87775415283696	0.00677932784183181	0.00748322408112632	0.00665274344810673	0.902674736201588	NA	NA	0.59446933004317	0.990152927452112	85.8983696497367
a9969	loss_cnaOV83	1021	Axitinib	PDGFR, KIT, VEGFR	5	25	0.693147180559945	NA	2.68757117749757	2.49282123638814	0.194749941109433	0.786366298385993	1.08212499865863	0.186361580511472	0.247658046268203	0.17996991230296	0.902739822201939	NA	NA	0.198521102044802	0.650738305517484	85.8983696497367
a9970	gain_cnaOV72_(ASXL1)	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.25166882578945	4.34086374298607	-0.0891949171966244	0.616179724783211	0.588661188786654	0.150777294876936	0.144754709720456	0.151521654384031	0.902810844199369	NA	NA	0.256952029573695	0.799753377338176	85.8983696497367
a9971	loss_cnaOV70	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	0.871699564795226	0.852879792085037	0.0188197727101886	1.63333221365406	2.12573785388268	0.00898572097751561	0.0115223177213198	0.00885328954170626	0.902980219957458	NA	NA	0.418971449155114	0.986611763722904	85.8983696497367
a9972	gain_cnaOV51_(MYC)	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	-0.0324433079829843	0.161974925904053	-0.194418233887037	0.973536492615411	1.76706527222416	0.118924757455662	0.199703077760065	0.110023232838664	0.902993981266483	NA	NA	0.464666753034182	0.710212116771886	85.8983696497367
a9973	loss_cnaOV70	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	1.01737632720586	0.915209302722024	0.102167024483839	1.41842062682276	1.26915226455961	0.0797935810684785	0.0720287216301214	0.0805002105238257	0.903160824336729	NA	NA	0.957750042603136	0.914220550347936	85.8983696497367
a9974	loss_cnaOV55	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	24	3.68887945411394	NA	3.50746280054543	3.48440404835842	0.0230587521870058	0.726231604114381	1.20562628684241	0.020526709564121	0.0317512375616389	0.0191259534058416	0.903263997482707	NA	NA	0.728443216970441	0.950868788188181	85.8983696497367
a9975	gain_cnaOV94	302	PI-103	PI3Ka, PRKDC (DNAPK)	7	25	2.32630161961136	NA	1.52849211069574	1.22308507984608	0.305407030849652	1.23153262903284	2.54596623326861	0.130357726078249	0.24798939439347	0.119957219722258	0.903278199050887	NA	NA	0.366351826434371	0.662448344145552	85.8983696497367
a9976	gain_cnaOV95_(MECOM)	329	QL-XI-92	DDR1	9	23	2.32630161961136	NA	4.57866979876141	4.5160675414798	0.0626022572816103	1.21610213219454	0.946203821844826	0.0610665368470858	0.0514777958399268	0.0661614927316124	0.903445167826221	NA	NA	0.193980297912736	0.89186528411548	85.8983696497367
a9977	RB1_mut	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	-1.38629436111989	0.693147180559945	-1.97581784485905	-2.13835165003154	0.162533805172487	0.295176669900297	1.34485243783794	0.124747161002328	0.550632288206879	0.120856237159956	0.903467921568385	NA	NA	0.609642705931015	0.59479040619076	85.8983696497367
a9978	loss_cnaOV54	253	XMD14-99	EPHB3, CAMK1	10	22	2.32630161961136	NA	4.95942866235187	4.81489807548245	0.14453058686942	0.546860115312627	0.651106757280976	0.232487268139806	0.264291695119867	0.221976788373354	0.903624813970819	NA	NA	0.0509650788493613	0.521744120664104	85.8983696497367
a9979	PTEN_mut	1494	SN-38	TOP1	3	29	-2.99573227355399	NA	-4.74466859000202	-4.1253870398347	-0.619281550167322	0.485577340587414	1.37833550983445	0.463018431906077	1.27535100673801	0.449296666703236	0.903688190625059	NA	NA	0.22046149475121	0.150798805261756	85.8983696497367
a9980	KRAS_mut	190	Bleomycin	DNA damage	3	16	4.15888308335967	NA	2.02379398655802	1.59977035244544	0.424023634112575	2.11989560418416	2.37597534822759	0.180643229330126	0.200020997862185	0.178462977079659	0.903818350314687	NA	NA	0.617236071097094	0.775496823718569	85.8983696497367
a9981	loss_cnaOV35	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.34335546201227	4.40716697581872	-0.0638115138064483	1.32924263081094	0.775733061357055	0.073580230049972	0.0480059188046944	0.0822596289692971	0.903961905460321	NA	NA	0.870279011071146	0.921477358933752	85.8983696497367
a9982	gain_cnaOV19	155	AP-24534	ABL	3	16	-0.669430653942629	NA	0.648450301443892	0.814819691844546	-0.166369390400654	2.00839664415269	1.14059606505333	0.13061327890392	0.0828369191339902	0.145861795860987	0.90405550320911	NA	NA	0.588307799179939	0.900689793009955	85.8983696497367
a9983	SMAD4_mut	1230	IOX2	EGLN1	4	28	-2.30258509299405	NA	-0.0918872326841625	-0.0592934363986857	-0.0325937962854768	1.50385118898273	0.893939992877333	0.0335222702617759	0.0216735515616573	0.0364608324330214	0.904164568559607	NA	NA	0.551354639618982	0.968689707406006	85.8983696497367
a9984	loss_cnaOV70	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.69753804637152	1.74181349572592	-0.0442754493543953	0.279679381271576	1.77132387257617	0.0258210455945758	0.15830787794615	0.0249956826303042	0.904389062633169	NA	NA	0.231946094167722	0.903541024998434	85.8983696497367
a9985	loss_cnaOV57_(ZNRF3)	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	5.81352840819996	5.71403806213825	0.0994903460617085	1.01380778719746	0.545098948219618	0.163516889437156	0.0981353145222295	0.182517956394266	0.90446478898885	NA	NA	0.194983543102003	0.858868476090427	85.8983696497367
a9986	loss_cnaOV36	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.43213924945974	2.38953965558858	0.0425995938711599	1.46790431763602	0.902016191354649	0.0448282552695335	0.0290206884463452	0.0472270833710687	0.904489691044259	NA	NA	0.736350707673568	0.964857426305549	85.8983696497367
a9987	loss_cnaOV56	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	2.88109580111745	2.55683572871054	0.324260072406906	2.00011656661983	2.37472889076813	0.137888420978945	0.162120587279021	0.13654614371665	0.904628002282332	NA	NA	0.388826088482991	0.812302361444835	85.8983696497367
a9988	PIK3R1_mut	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	1.37712404041398	1.61481004245131	-0.237686002037329	0.640868186060148	1.15911007336715	0.220131030160924	0.370881262648637	0.205059042707535	0.904649319297737	NA	NA	0.458047184199134	0.55930420471773	85.8983696497367
a9989	NF1_mut	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	4.90503141387982	4.91181916235836	-0.00678774847854413	1.03665625863202	0.845710117989332	0.00782526432048589	0.00654773308126392	0.00802609349723986	0.904773777064064	NA	NA	0.156747183418353	0.990689770752506	85.8983696497367
a9990	gain_cnaOV96	306	TG101348	JAK2	5	27	2.32630161961136	NA	2.94022383049928	2.80254654190021	0.137677288599066	1.35062127492247	1.41601476654416	0.0978189034878263	0.10193626529907	0.0972287096518583	0.904864199952672	NA	NA	0.629534802120082	0.842562453295144	85.8983696497367
a9991	loss_cnaOV83	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.51747264206866	3.48425282900296	0.0332198130657035	0.590967104920292	1.18654217573499	0.0295727071111109	0.0562126263697607	0.0279971616222794	0.90489169273527	NA	NA	0.72844556012406	0.926463758694268	85.8983696497367
a9992	loss_cnaOV55	328	SNX-2112	HSP90	7	25	0.940007258491471	NA	0.800341933892018	0.666975064889729	0.133366869002289	2.7311581895018	2.2171374768644	0.0572627164507369	0.0488316163871186	0.0601527286394995	0.904936222760735	NA	NA	0.946167448218068	0.908314216067631	85.8983696497367
a9993	SMAD4_mut	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.35443819058713	2.39911839278927	-0.0446802022021413	1.22996871680576	0.913898721323425	0.0470194956527053	0.0363262915484358	0.0488896648607184	0.904981653007454	NA	NA	0.736351368227959	0.948056868870795	85.8983696497367
a9994	loss_cnaOV84	1230	IOX2	EGLN1	6	26	-2.30258509299405	NA	-0.151004441876176	-0.0431437884093383	-0.107860653466837	1.18172492664342	0.923597623635268	0.11103698866416	0.0912739090417643	0.116783164775045	0.905027773914108	NA	NA	0.551356452120452	0.840631134407826	85.8983696497367
a9995	gain_cnaOV96	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.69274104412627	5.84090507212593	-0.148164027999655	1.16352901214595	1.31013981710524	0.114304236499115	0.12734020935704	0.113090241259153	0.905108039134845	NA	NA	0.573287856152814	0.825779864574525	85.8983696497367
a9996	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.32180703264486	2.4068160221194	-0.0850089894745394	1.09378711396551	0.925705176156858	0.0894985804036645	0.0777198674121702	0.0918316021818753	0.905180305386153	NA	NA	0.73635163397162	0.876540149858032	85.8983696497367
a9997	loss_cnaOV81_(RB1)	193	GW-2580	CSF1R (cFMS)	4	28	2.99573227355399	NA	5.81326727924568	5.71407536627457	0.0991919129711087	0.74589156163859	0.591205637602532	0.163024878003584	0.132984361363737	0.167779037719183	0.905201244334095	NA	NA	0.194985233976537	0.812922595067645	85.8983696497367
a9998	loss_cnaOV38	1219	PFI-1	BRD2, BRD3, BRD4	8	24	2.30258509299405	NA	2.29511599459208	2.38374231176457	-0.088626317172495	1.12701433665653	0.785212085911129	0.101060408784764	0.0786381453100404	0.112869272853406	0.905320254503535	NA	NA	0.61009293561261	0.840927549990248	85.8983696497367
a9999	loss_cnaOV84	1502	Bicalutamide	ANDR (androgen receptor)	5	27	2.30258509299405	NA	4.56928773357434	4.50633020394139	0.0629575296329525	0.344354097965281	0.634187199574133	0.104296913408155	0.182827879804411	0.0992727851890254	0.905354672366126	NA	NA	0.617193380597042	0.755265504712898	85.8983696497367
a10000	loss_cnaOV56	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.27201363057572	2.36569963443765	-0.0936860038619307	1.53266298235936	0.807050786642798	0.107147583995209	0.0611262912592252	0.116084396933246	0.905423132435281	NA	NA	0.652539406057367	0.925920435131886	85.8983696497367
a10001	loss_cnaOV21, loss_cnaOV22	256	JW-7-24-1	LCK	3	29	2.32630161961136	NA	2.04793192399095	1.92811099405031	0.119820929940637	0.834568553063611	1.38210540326521	0.0885910939011012	0.143572303917739	0.0866944949766937	0.905442001974445	NA	NA	0.840013517575146	0.839246273090583	85.8983696497367
a10002	NF1_mut	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	0.693147180559945	2.7335526172093	2.8316264108288	-0.0980737936194993	1.39991983002005	1.58995465912051	0.0623653688877526	0.0700567214753252	0.0616833901878366	0.905555431529231	NA	NA	0.968994644885169	0.903298201709987	85.8983696497367
a10003	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1050	ZM-447439	AURKB	7	15	1.38629436111989	0.693147180559945	2.59099413479125	2.3819344085922	0.209059726199046	1.98306941778411	1.40066459719717	0.130839485508988	0.105422293503296	0.149257521477582	0.905580606307719	NA	NA	0.231667636412943	0.807349587632516	85.8983696497367
a10004	gain_cnaOV50	287	KIN001-244	PDPK1 (PDK1)	4	28	2.99573227355399	NA	3.46640544912547	3.55551084749646	-0.089105398370986	0.449649161063979	0.948607114507168	0.0978006761113997	0.198166495318574	0.0939328801231679	0.905946264795909	NA	NA	0.665189627104155	0.764890302953432	85.9180524888295
a10005	gain_cnaOV4_(KRAS)	1053	MK-2206	AKT1, AKT2	6	26	1.38629436111989	0.693147180559945	1.24741303114136	1.32430970585722	-0.0768966747158601	0.852660248783308	1.28948041638095	0.0626439416241211	0.0901844255382925	0.059633844561733	0.905969215252982	NA	NA	0.0994662020328549	0.861389831556456	85.9180524888295
a10006	loss_cnaOV81_(RB1)	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.19932907875456	3.04972242538553	0.149606653369032	0.509021564625772	0.95871036001148	0.16177215000104	0.293910246177923	0.156049897455203	0.906080385932066	NA	NA	0.241580532828549	0.645856409918514	85.9200077099496
a10007	loss_cnaOV70	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-0.25430719313183	-0.340392598724196	0.0860854055923663	0.563658226634286	1.45908801768454	0.0606885030408917	0.152726247084868	0.0589994603128722	0.906540604536639	NA	NA	0.889620550858607	0.845290997572035	85.9245413197943
a10008	loss_cnaOV70	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-2.98547423278338	-3.35051452381572	0.365040291032337	2.42609214804652	1.78330648987525	0.198945041202582	0.150464314113652	0.204698571504595	0.906607701253942	NA	NA	0.141872220013652	0.821383951559696	85.9245413197943
a10009	loss_cnaOV16, loss_cnaOV17	235	QL-XII-47	BTK, BMX	6	26	2.32630161961136	NA	1.82334753177835	1.50573684964923	0.317610682129122	1.31225600548262	1.68596549822563	0.194895887719482	0.242034085423989	0.188385042554778	0.906651507933413	NA	NA	0.0805647175659129	0.625684168979902	85.9245413197943
a10010	gain_cnaOV48_(SOX17)	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	3.08370326409664	2.81937139508313	0.264331869013504	1.68109719406353	1.87913740826591	0.141612285787769	0.157237707579871	0.1406665993933	0.906738054940301	NA	NA	0.349224668832518	0.81699745389598	85.9245413197943
a10011	loss_cnaOV52, loss_cnaOV53	231	FMK	RSK	5	15	2.99573227355399	2.32630161961136	5.38300651142981	5.1961383698224	0.186868141607416	0.751350622114208	0.746679918682681	0.249917145586025	0.248709638492868	0.250265390740781	0.906762427756217	NA	NA	0.130195338228446	0.644562739631696	85.9245413197943
a10012	loss_cnaOV58	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	3.03103449840583	2.89234060908217	0.13869388932366	0.855534957937305	0.861479749455543	0.16120624932447	0.162113643676292	0.160994950155607	0.90682635571419	NA	NA	0.334119220483338	0.758938503598467	85.9245413197943
a10013	loss_cnaOV34	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	1.57981848089768	1.55850603120584	0.0213124496918453	1.85653457369426	0.801299274782886	0.0196505517625755	0.011479694476918	0.0265973655069387	0.906878404833352	NA	NA	0.45805475357737	0.981120579556289	85.9245413197943
a10014	loss_cnaOV57_(ZNRF3)	1053	MK-2206	AKT1, AKT2	4	28	1.38629436111989	0.693147180559945	1.39921240383086	1.29713146156473	0.102080942266136	1.14694866694268	1.23603340945949	0.0831673600798528	0.0890021892071637	0.0825875267487925	0.90689330775026	NA	NA	0.0994677544283987	0.876932140574901	85.9245413197943
a10015	loss_cnaOV81_(RB1)	333	T0901317	LXR	4	28	2.32630161961136	NA	4.90021648843866	4.73237107469072	0.167845413747939	0.863684864023996	1.15293930035987	0.148883791205761	0.194336407571079	0.145580442695942	0.906943222052488	NA	NA	0.0053529645633967	0.743616244060695	85.9245413197943
a10016	loss_cnaOV54	330	XMD13-2	RIPK	10	22	2.32630161961136	NA	4.06733953526892	4.09160522581982	-0.0242656905509042	0.815400746407165	1.23995451103295	0.0214841216787475	0.0297592204297386	0.0195698231951183	0.907191799631336	NA	NA	0.820711032789402	0.948117756045237	85.9334261310158
a10017	PIK3CA_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	4.2862863929966	3.96168288085773	0.324603512138873	1.46172518805549	1.51386275963784	0.21588710748503	0.222068768323469	0.214420699678567	0.907281890519153	NA	NA	0.332643446244231	0.61766932104856	85.9334261310158
a10018	loss_cnaOV59	290	KIN001-260	IKK	4	27	2.99573227355399	NA	4.82793477477534	4.85355185029577	-0.0256170755204286	1.19978156947715	0.869793075631122	0.0281661376492248	0.0213514494405778	0.0294519193566134	0.907308705782091	NA	NA	0.667336236520409	0.969438217316652	85.9334261310158
a10019	PIK3R1_mut	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.3336628508731	4.42312924086387	-0.0894663899907711	0.591863220538049	0.642900886551272	0.140596937583778	0.151160583875172	0.139160470707542	0.907570951896055	NA	NA	0.274007407109131	0.769973762741866	85.9496845764174
a10020	loss_cnaOV58	1053	MK-2206	AKT1, AKT2	5	27	1.38629436111989	0.693147180559945	1.52026622737843	1.27093331119421	0.249332916184221	1.02950889963546	1.25163195838438	0.203645780490499	0.242186265968665	0.199206255891758	0.907672713940793	NA	NA	0.0994690516370554	0.647263563998884	85.9507429718984
a10021	ARID1A_mut	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	2.22222951516368	2.10963533169528	0.112594183468397	1.87230540354058	1.45394101772181	0.0720607269981275	0.0601366546587315	0.077440681634267	0.907775988940443	NA	NA	0.948293317218207	0.907017457889298	85.9519444089047
a10022	gain_cnaOV50	205	BMS-708163	g-secretase	4	28	2.32630161961136	0.940007258491471	5.16092672111277	5.04787285034274	0.113053870770029	0.652603126502116	0.617907439580773	0.181915344967482	0.173235257661094	0.18296246901758	0.907974573220198	NA	NA	0.112668412717765	0.761388251202074	85.9526172073761
a10023	loss_cnaOV54	1192	GSK269962A	ROCK1, ROCK2	10	22	1.6094379124341	NA	2.52948235304549	2.39882007965208	0.130662273393402	1.75803351204037	1.3258816600024	0.0889501782073368	0.0743229708071694	0.0985474626696067	0.908352508144023	NA	NA	0.24292939333911	0.837104522788456	85.9526172073761
a10024	loss_cnaOV52, loss_cnaOV53	279	BIX02189	MAP2K5 (MEK5)	8	24	2.99573227355399	NA	4.4250990143877	4.43321102370722	-0.00811200931952527	0.837707642296668	0.712923291699954	0.0109044959312076	0.00968358041629572	0.0113785163340397	0.908359777328822	NA	NA	0.526868096047575	0.980844860175537	85.9526172073761
a10025	MLL2_mut	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	1.61375452882476	2.5802479729446	-0.966493444119846	1.22516703448743	1.59596330085154	0.618418256635259	0.788866674432025	0.605586258533743	0.908364364115534	NA	NA	0.231677600483558	0.307104264886752	85.9526172073761
a10026	loss_cnaOV33_(ZFHX3)	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	4.90908737383142	4.85306052817168	0.0560268456597379	0.683338644110528	0.61842137535036	0.0896119119339016	0.0819898686289953	0.0905965542151523	0.908545687004985	NA	NA	0.05097065825768	0.884714646450467	85.9526172073761
a10027	gain_cnaOV96	288	KIN001-055	JAK3, MNK1	5	27	2.32630161961136	NA	3.87598201804525	3.78709992346507	0.0888820945801712	0.929198992081362	1.05504693406612	0.0855336098011001	0.0956545318469185	0.0842446830660149	0.908859575064354	NA	NA	0.718837680361176	0.853857782060125	85.9526172073761
a10028	loss_cnaOV84	1059	AZD8055	MTORC1/2	6	27	0.693147180559945	NA	0.450842334824578	0.243408905325648	0.207433429498931	1.20009926978234	1.13420970031426	0.181149771989514	0.172846892521277	0.182888075671947	0.908903904702103	NA	NA	0.14912034462589	0.710235141658529	85.9526172073761
a10029	PTEN_mut	193	GW-2580	CSF1R (cFMS)	3	29	2.99573227355399	NA	5.46293814513684	5.75373672197449	-0.290798576837654	0.385274696824803	0.615683972194047	0.482198389182703	0.754782442849832	0.472317926031704	0.908939415385122	NA	NA	0.194993611281727	0.324702501261663	85.9526172073761
a10030	loss_cnaOV38	1001	AICAR	AAPK1 (AMPK) agonist	8	23	7.60090245954208	NA	8.85492176534812	8.71294188219768	0.141979883150444	1.20427888083413	1.25632970746873	0.114134937356099	0.117896182860986	0.113011642012755	0.90900163459751	NA	NA	0.532507394324358	0.780971724173757	85.9526172073761
a10031	loss_cnaOV21, loss_cnaOV22	1199	Tamoxifen	ER	3	29	1.6094379124341	NA	3.96900913758645	3.98096629138097	-0.0119571537945213	0.656122527653835	0.775168154423183	0.0155731398322735	0.0182239647178062	0.0154252386740769	0.909297181261294	NA	NA	0.528088422137378	0.978564353435003	85.9526172073761
a10032	PIK3CA_mut	287	KIN001-244	PDPK1 (PDK1)	6	26	2.99573227355399	NA	3.59259161868343	3.53324522362701	0.0593463950564255	1.17978702682263	0.847438087341609	0.0651237804894019	0.0503026340408707	0.0700303608521934	0.90934152251013	NA	NA	0.665195091439387	0.910931411998994	85.9526172073761
a10033	loss_cnaOV38	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	24	2.99573227355399	NA	3.97093169255026	4.05327596800072	-0.0823442754504637	1.54156265686915	1.49961170057091	0.0545505317882135	0.0534161067560508	0.0549103980844605	0.909360245912952	NA	NA	0.332648484641553	0.897425955788547	85.9526172073761
a10034	gain_cnaOV96	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	1.69186352181857	1.66001690076846	0.0318466210501187	1.87055936448679	2.44395521628004	0.0135348017702927	0.0170251859709655	0.0130307711196904	0.909384118153388	NA	NA	0.617254623803268	0.978384732619343	85.9526172073761
a10035	ARID1A_mut	328	SNX-2112	HSP90	8	24	0.940007258491471	NA	0.726707824577508	0.68596281511947	0.0407450094580375	1.45321564698727	2.5370007687214	0.0174896830679451	0.0280378273813029	0.0160603063114452	0.909459740938428	NA	NA	0.946168702868141	0.955970596082364	85.9526172073761
a10036	KRAS_mut	1019	Bosutinib	SRC, ABL, TEC	7	24	0.693147180559945	NA	1.58388792010445	1.76421439011354	-0.180326470009091	1.87208959818981	1.53513790626789	0.111959100237919	0.0963236322574814	0.117465974407138	0.909526996126978	NA	NA	0.0424287324709152	0.821260115552844	85.9526172073761
a10037	ARID1A_mut	219	AT-7519	CDK9	8	24	2.32630161961136	NA	1.10311910839255	1.62923723861715	-0.526118130224597	1.45121127592162	1.77201522551705	0.309012969875415	0.362537239720988	0.296903842951508	0.909611047112594	NA	NA	0.319026062732577	0.415502806959652	85.9526172073761
a10038	loss_cnaOV54	310	YM201636	FYV1	10	22	1.63315443905142	NA	2.3556981676295	2.35747039155109	-0.00177222392159404	0.897325750120969	0.864993212184438	0.00202581908272195	0.00197500620187833	0.00204882985973786	0.909659122193082	NA	NA	0.652546450358205	0.995882972779719	85.9526172073761
a10039	loss_cnaOV57_(ZNRF3)	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.556416394888817	-0.7657684228352	0.209352027946383	1.39290500574677	0.864017623165712	0.225482596007212	0.150298855329437	0.242300645650408	0.909659759111194	NA	NA	0.0430815647906214	0.786920086908852	85.9526172073761
a10040	loss_cnaOV41	1043	JNK Inhibitor VIII	JNK	5	28	2.30258509299405	NA	4.55662250346818	4.4215743115914	0.135048191876778	1.09056567887743	1.00520026444898	0.132840642831414	0.123833157867015	0.134349538746696	0.909669617753898	NA	NA	0.377714588302609	0.806136423932313	85.9526172073761
a10041	loss_cnaOV38	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	4	15	1.63315443905142	NA	1.33982096362041	1.13377876519764	0.206042198422761	2.52518042551612	1.31934419372005	0.12880749051573	0.0815950402358469	0.156170163482359	0.909759848235958	NA	NA	0.538992106874422	0.8835900061239	85.9526172073761
a10042	loss_cnaOV20	1061	SB590885	BRAF	5	28	1.6094379124341	NA	3.81246466631438	3.94808895960297	-0.135624293288586	2.01343008138056	1.14842635254971	0.104893073372107	0.0673598226940124	0.118095769038629	0.90979001922837	NA	NA	0.575392118397809	0.889946131151273	85.9526172073761
a10043	loss_cnaOV55	172	Embelin	XIAP	4	15	3.46573590279973	NA	3.01450519513909	3.12024235145107	-0.105737156311975	1.48302187802549	0.817918189203034	0.109114448425012	0.071298446690992	0.129275956578254	0.90982897955613	NA	NA	0.674337376429876	0.898433711517735	85.9526172073761
a10044	BRCA1_mut	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.92622237322185	5.80755059654085	0.118671776681007	1.13715951108608	1.31309838247166	0.091526819457849	0.10435807424032	0.0903753886724231	0.909866620372383	NA	NA	0.573297191285795	0.85712241836922	85.9526172073761
a10045	loss_cnaOV35	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.75201978017701	5.72174372117725	0.030276058999763	0.929357736457683	0.543562319219744	0.0496912692562885	0.0325774002970724	0.0556993336904272	0.910074299391703	NA	NA	0.194996086738814	0.946699881515097	85.9636773682983
a10046	loss_cnaOV102	219	AT-7519	CDK9	3	29	2.32630161961136	NA	1.50767790934146	1.49667630572164	0.0110016036198155	1.32357645964823	1.74355686956265	0.00640091864137192	0.00831202726492991	0.00630986222008069	0.910390091300649	NA	NA	0.319027916161374	0.99031776886084	85.9768195648285
a10047	loss_cnaOV52, loss_cnaOV53	230	GSK429286A	ROCK2	8	24	2.99573227355399	2.32630161961136	5.57382569000871	5.52705250169253	0.0467731883161751	1.45820562471904	0.791780498121444	0.0473256897629312	0.0320758523511986	0.0590734280866324	0.910394659450951	NA	NA	0.307093188247909	0.933037117558076	85.9768195648285
a10048	loss_cnaOV16, loss_cnaOV17	254	AC220	FLT3	6	26	0.0237165266173161	NA	2.47663239034086	2.51870879300848	-0.0420764026676239	0.397085069941327	0.671852630433151	0.0663271077137528	0.105963194924053	0.0626274286378797	0.910512746095015	NA	NA	0.85896139015546	0.843567965253712	85.9794138368728
a10049	loss_cnaOV54	1377	Afatinib (rescreen)	ERBB2, EGFR	11	22	2.30258509299405	NA	2.54889978031997	2.70821498089419	-0.159315200574218	1.90126829622564	1.61901221199604	0.0928872923498622	0.0837941709176381	0.0984027170355941	0.910794113194971	NA	NA	0.642006170797628	0.814584999987773	85.9866807273583
a10050	loss_cnaOV35	281	CH5424802	ALK	5	27	1.63315443905142	NA	3.89613817342169	3.93343296693465	-0.0372947935129688	1.1435759386096	0.650379686613729	0.0507065754370271	0.0326124328554106	0.0573431093876073	0.910846721707257	NA	NA	0.956058256114421	0.946574774358112	85.9866807273583
a10051	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1026	17-AAG	HSP90	5	28	0	NA	-0.113737344569419	-0.605313375025876	0.491576030456457	2.45377823499675	2.28611529299852	0.212947876075894	0.200334334800678	0.215026788877168	0.910870192496513	NA	NA	0.0627399332545546	0.693106562340112	85.9866807273583
a10052	loss_cnaOV16, loss_cnaOV17	295	NVP-BHG712	EPHB4	6	26	2.32630161961136	NA	3.0732323456819	3.29218300729127	-0.218950661609361	1.04437622731266	1.10166608965094	0.200444344848296	0.209647305140939	0.198745031426659	0.91095219758411	NA	NA	0.0639012194198955	0.659399047450807	85.9866807273583
a10053	PTEN_mut	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-4.17099579523902	-3.18840171052719	-0.982594084711828	1.17896914965075	1.86531381551899	0.543937632929393	0.833434941875202	0.526771461475742	0.911257213576497	NA	NA	0.141881570400745	0.208254329387856	85.9949275866788
a10054	gain_cnaOV26	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.49530507711399	4.40023753539131	0.0950675417226821	0.829377769380667	0.620513320399978	0.149342660393972	0.114625138546543	0.153207898359704	0.911332851966275	NA	NA	0.274016304477404	0.863062449344003	85.9949275866788
a10055	gain_cnaOV96	228	KIN001-102	AKT1	5	27	2.32630161961136	NA	2.87189446584264	2.7734835159976	0.0984109498450407	0.907819225395747	1.28164746014776	0.0794699789753111	0.108403685548894	0.0767847266156129	0.911360146486633	NA	NA	0.0967197263055804	0.841510677066215	85.9949275866788
a10056	loss_cnaOV70	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.472735552060086	0.26196292655199	0.210772625508096	0.757176020706607	1.16843330218038	0.183862266408187	0.278366746627026	0.180389094623356	0.911436497218936	NA	NA	0.149125140784411	0.69357761130631	85.9949275866788
a10057	loss_cnaOV1	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.26152251840064	4.27963863332404	-0.0181161149233988	0.297599809577258	0.931527790981019	0.0200573492128662	0.0608740810322858	0.0194477449828096	0.911610622658753	NA	NA	0.524077045768098	0.942698280896517	85.9949275866788
a10058	loss_cnaOV34	1007	Docetaxel	Microtubules	5	26	-4.38202663467388	NA	-4.54303634287186	-4.66887087828566	0.125834535413805	2.01149765735625	1.31615186218706	0.0878564470628204	0.062557634583175	0.0956079150355075	0.911685850735928	NA	NA	0.137830169967323	0.898629188812271	85.9949275866788
a10059	loss_cnaOV41	1192	GSK269962A	ROCK1, ROCK2	5	27	1.6094379124341	NA	2.50617105544227	2.42733370391072	0.0788373515315532	2.72559364567428	1.16204482729666	0.053631887354302	0.0289248368540461	0.0678436405202696	0.911799835631171	NA	NA	0.24293732076256	0.952141893290744	85.9949275866788
a10060	TP53_mut	150	Bicalutamide	ANDR (androgen receptor)	12	7	0.0237165266173161	NA	2.96539894511606	2.99348036644814	-0.0280814213320753	0.683419735730163	0.445090829516712	0.0460328502952464	0.0410895674560425	0.0630914399260182	0.911943850135084	NA	NA	0.851185498771361	0.915044855922135	85.9949275866788
a10061	loss_cnaOV21, loss_cnaOV22	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.54732581120775	5.53785821127818	0.0094675999295708	0.664706882000297	1.00769953600125	0.00957732956972552	0.0142432705090701	0.00939526078094676	0.912070361181818	NA	NA	0.307097114283025	0.983679214580964	85.9949275866788
a10062	loss_cnaOV59	286	KIN001-236	TIE2	4	28	2.32630161961136	NA	4.84391965445064	4.78809227621905	0.0558273782315908	0.995543807608694	0.622751833518684	0.083394269093249	0.0560772693325156	0.0896462687490679	0.912097648096687	NA	NA	0.763502327293911	0.919314077236438	85.9949275866788
a10063	loss_cnaOV52, loss_cnaOV53	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	23	2.30258509299405	NA	2.08059711953015	2.19673860036804	-0.116141480837884	2.08741658152257	0.939576746139784	0.0885190318288342	0.0556388609087171	0.123610424922761	0.912097956137389	NA	NA	0.688404497708953	0.882868218211843	85.9949275866788
a10064	loss_cnaOV59	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	3.841894193958	4.05994642844955	-0.218052234491554	1.34962633027327	1.52470901713686	0.144585879667295	0.161564893630524	0.14301235976227	0.912127157704331	NA	NA	0.332655011985795	0.780527262531545	85.9949275866788
a10065	SMARCA4_mut	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	1.72434548611789	1.91801122534929	-0.1936657392314	0.891990597643471	1.41761424237306	0.13935641126241	0.217116346005261	0.136613849834922	0.912252379137647	NA	NA	0.0352630199268078	0.758173325519832	85.9965033822634
a10066	gain_cnaOV48_(SOX17)	1194	SB-505124	TGFR1 (ALK5)	3	29	2.30258509299405	NA	4.64146483704203	4.58295157462823	0.0585132624137987	0.781154944566401	0.963140138063566	0.0614576613500405	0.0749060897851423	0.0607525946654472	0.91269069272655	NA	NA	0.943488225630064	0.912485171915394	85.9965033822634
a10067	loss_cnaOV52, loss_cnaOV53	196	Phenformin	AAPK1 (AMPK) agonist	8	23	8.29404964010203	NA	8.68805470387765	8.78166648118985	-0.0936117773121943	2.01733407135271	1.61810254152302	0.0543319687416291	0.0464037060799867	0.0578528090216602	0.912706622562114	NA	NA	0.922287414477372	0.907835247174802	85.9965033822634
a10068	SMARCA4_mut	206	Ruxolitinib	JAK1, JAK2, TYK2	3	29	1.65632149833295	0.0237165266173161	4.36116728935104	4.46132375730954	-0.100156467958501	0.946518681415089	0.521813721075027	0.178775763922548	0.105815627229631	0.19193912293483	0.912757813174308	NA	NA	0.367752164242766	0.872529536280633	85.9965033822634
a10069	gain_cnaOV95_(MECOM)	312	AV-951	VEGFR	9	23	-2.05572501506252	NA	0.632914510198078	0.642559885749328	-0.00964537555125011	0.524997247815876	0.654125228199812	0.0154991493524911	0.0183722402191199	0.0147454571929517	0.912830465078189	NA	NA	0.0156671103286535	0.965797799389298	85.9965033822634
a10070	loss_cnaOV85	170	Shikonin	unknown	5	13	2.77258872223978	NA	-0.0829124674771713	0.0162695169349229	-0.0991819844120941	0.525893916147458	0.874344697297795	0.123736035432718	0.188596942019546	0.113435793364586	0.91293736877268	NA	NA	0.588623075277905	0.773933686896518	85.9965033822634
a10071	loss_cnaOV1	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.6183850360838	4.47567914630521	0.142705889778587	1.08918975140807	0.640344139702232	0.209594767225956	0.131020228196328	0.222858117894148	0.912994919541144	NA	NA	0.0548469157355262	0.843050278574678	85.9965033822634
a10072	gain_cnaOV19	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.42344103473177	3.47200005673431	-0.0485590220025385	1.26216941700675	1.10705653951996	0.0431093798962162	0.038472665672487	0.043863181571191	0.913012536218076	NA	NA	0.775476108065019	0.954781874102893	85.9965033822634
a10073	gain_cnaOV50	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	3.94972656106977	3.91543248913189	0.0342940719378841	1.10378335090011	1.24556455076398	0.0278439030188644	0.0310695680542003	0.0275329543674388	0.913204931312563	NA	NA	0.700566281443587	0.957145777900312	85.9965033822634
a10074	gain_cnaOV50	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.63225381467377	4.58217767559464	0.0500761390791338	0.604184756413075	0.983186620749443	0.0525954660433261	0.0828821623644162	0.0509324862872552	0.913285776384425	NA	NA	0.943488387883029	0.892648338205465	85.9965033822634
a10075	loss_cnaOV34	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	26	3.68887945411394	NA	3.41136982262948	3.50465721735664	-0.093287394727164	0.945821373245754	1.14863132235073	0.083081827368529	0.0986310918382313	0.0812161334206409	0.913286371958942	NA	NA	0.728457002006472	0.851594852525817	85.9965033822634
a10076	NF1_mut	1043	JNK Inhibitor VIII	JNK	4	29	2.30258509299405	NA	4.4505848928683	4.44085702311817	0.00972786975013129	0.671198965103719	1.04820245848732	0.00955737035960813	0.0144932728682442	0.00928052560014961	0.913319020511035	NA	NA	0.377722750450313	0.980913682747339	85.9965033822634
a10077	gain_cnaOV72_(ASXL1)	231	FMK	RSK	4	16	2.99573227355399	2.32630161961136	5.13559342375759	5.26967090059092	-0.134077476833324	0.909281707682396	0.714450240468729	0.178664417442112	0.147454277041452	0.187665241382465	0.913322118039839	NA	NA	0.130215663069932	0.797373883177375	85.9965033822634
a10078	loss_cnaOV85	1042	BIRB 0796	p38, JNK2	7	26	2.30258509299405	NA	4.35527681407377	4.40886595901805	-0.0535891449442767	0.881712605310714	0.863760283347889	0.0617910455693052	0.0607784720571075	0.06204168677051	0.913656895146243	NA	NA	0.870285113200793	0.889056577235972	86.0182443470597
a10079	ARID1A_mut	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.04879420649732	2.17471016427129	-0.125915957773979	1.62138708700752	1.28682071393639	0.0913693643992866	0.077659405815531	0.097850428121258	0.913734331491282	NA	NA	0.893517936932822	0.881254446265083	86.0182443470597
a10080	loss_cnaOV82	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.74268085003697	2.80338477248171	-0.0607039224447381	1.9005426948269	0.86968844398222	0.0625914426323138	0.0319403097914971	0.0697996194669216	0.914447459690802	NA	NA	0.966393627992619	0.961133675945339	86.0715513965993
a10081	loss_cnaOV70	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.03375910180953	4.08922182811368	-0.0554627263041514	0.848777712685707	1.14682752066539	0.0491078190261119	0.0653442302680827	0.0483618724740508	0.914508320107293	NA	NA	0.82071741507835	0.924264989555599	86.0715513965993
a10082	loss_cnaOV20	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	0.906414595792737	1.02228203574461	-0.115867439951876	1.23481186006044	1.60580920981635	0.07420530029229	0.0938340841220983	0.0721551721360016	0.914572729321217	NA	NA	0.792254763231168	0.860063972658621	86.0715513965993
a10083	loss_cnaOV58	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.80616769405528	5.71171632971831	0.0944513643369698	0.87813755904201	0.555341618241653	0.155256006459377	0.107558734237504	0.170077950642392	0.91466739281399	NA	NA	0.195005783238655	0.826429604493842	86.0719231056119
a10084	gain_cnaOV51_(MYC)	193	GW-2580	CSF1R (cFMS)	8	24	2.99573227355399	NA	5.76042100995381	5.71515880387668	0.0452622060771235	0.635131092976582	0.600891280382199	0.0743157385009969	0.0712643524740685	0.075325117129898	0.9148822657011	NA	NA	0.195006224221227	0.862669681449991	86.0788553874302
a10085	KRAS_mut	133	Doxorubicin	DNA intercalating	3	16	0.0237165266173161	NA	-1.61350194380912	-1.56454036529404	-0.0489615785150752	0.850985515497754	1.38124783610355	0.0368164391546253	0.0575351490987915	0.0354473521950948	0.914922502889441	NA	NA	0.625845376654771	0.938656484516337	86.0788553874302
a10086	loss_cnaOV39	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	9	23	0.246860077931526	2.32630161961136	0.929305519534853	1.03347557688063	-0.104170057345779	1.83530583578369	1.44886958664725	0.0667200972784803	0.0567589637185988	0.0718974697970115	0.915378446113608	NA	NA	0.79225553443882	0.88116762229407	86.0899140097936
a10087	loss_cnaOV54	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	10	21	1.6094379124341	NA	1.24287850461804	1.38609739800565	-0.143218893387612	1.85762777904852	1.06570865512215	0.105177372775373	0.0770977345423684	0.134388411597536	0.915381851836289	NA	NA	0.583237089860338	0.824511123665158	86.0899140097936
a10088	loss_cnaOV38	1239	YK 4-279	RNA helicase A	6	18	2.30258509299405	NA	1.72864993370672	1.51646222384235	0.21218770986437	0.721419121628948	1.14423273237697	0.199610237627162	0.294125430700055	0.185441041721977	0.915418722454851	NA	NA	0.290993160067605	0.603511293363723	86.0899140097936
a10089	loss_cnaOV16, loss_cnaOV17	152	CP466722	ATM	6	26	2.77258872223978	NA	2.7118501678144	2.63193203513603	0.0799181326783658	0.821791917501216	0.819608294029071	0.0974643899776291	0.0972486233758165	0.097507715893772	0.915533160488602	NA	NA	0.558326829290526	0.83564330810336	86.0899140097936
a10090	PIK3CA_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	1.00676147846547	1.23801128143707	-0.231249802971599	0.636561841712211	1.79347485672731	0.144670777766241	0.363279398509952	0.128939528817024	0.915632523916969	NA	NA	0.53901309895507	0.683490946736794	86.0899140097936
a10091	gain_cnaOV26	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.628932765177398	-0.541581711602326	-0.0873510535750712	1.11646012252007	1.55237971600979	0.0579385016842207	0.0782392956211484	0.0562691284060301	0.915652580395756	NA	NA	0.910204652466525	0.913681058207687	86.0899140097936
a10092	loss_cnaOV43_(NF1)	276	CAY10603	HDAC6	5	26	2.99573227355399	NA	1.44810761941194	1.4303215298841	0.0177860895278399	1.3633566464676	1.8664803652523	0.00985139323636109	0.0130458083539057	0.00952921330379794	0.91567517317713	NA	NA	0.616877549096356	0.980721129408353	86.0899140097936
a10093	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	271	VNLG/124	HDAC, RAR 	7	24	1.63315443905142	NA	4.30346145165357	4.33690692509195	-0.0334454734383831	0.382040414712482	0.635696455560641	0.0564768339794978	0.0875443334013593	0.0526123327349473	0.91595910038105	NA	NA	0.256983932843899	0.865282242293813	86.0996507223848
a10094	loss_cnaOV84	283	GSK2126458	PI3K, MTOR	6	26	-2.05572501506252	0.0237165266173161	-2.75445749453201	-2.72704269020711	-0.0274148043249003	0.79860091689223	1.9205366298458	0.0153734314169125	0.0343285410084245	0.0142745542567972	0.916011058408861	NA	NA	0.698034065272355	0.956655883148855	86.0996507223848
a10095	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1021	Axitinib	PDGFR, KIT, VEGFR	8	22	0.693147180559945	NA	2.51986558767335	2.52724827708202	-0.00738268940866993	1.34866968104225	0.925889493143287	0.0070465498069155	0.00547405307055217	0.00797361830255418	0.916050964549111	NA	NA	0.198552480012453	0.988881813139716	86.0996507223848
a10096	loss_cnaOV70	1049	PD-173074	FGFR1, FGFR3	3	30	0.693147180559945	NA	3.17004400302739	2.96815650866774	0.201887494359654	1.07241485153254	1.00832101958563	0.199379590160542	0.188255034020786	0.200221447771286	0.91624293188516	NA	NA	0.0895159825497394	0.780054315093938	86.1091638541079
a10097	KRAS_mut	326	GSK690693	AKT	7	25	2.32630161961136	NA	3.98986827633975	4.19730875298445	-0.207440476644699	0.54827633965784	1.61743363874434	0.141374807435121	0.378350225315497	0.128252851724873	0.916348676203953	NA	NA	0.0954922063392552	0.593409514531976	86.110572603405
a10098	loss_cnaOV82	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	3	20	2.30258509299405	NA	3.89966300785605	3.84668025042658	0.0529827574294743	1.50395307774424	0.802443927514461	0.0593104277445752	0.0352289963121341	0.0660267410753377	0.916589080456119	NA	NA	0.940397832102839	0.95739448923937	86.1179776478237
a10099	loss_cnaOV20	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.34662285610598	1.33890144369908	0.00772141240690027	2.33449722235989	1.20193494297068	0.00566316467697508	0.00330752691969146	0.00642415169977185	0.916609001949455	NA	NA	0.583239311357102	0.995201839550396	86.1179776478237
a10100	loss_cnaOV59	1194	SB-505124	TGFR1 (ALK5)	4	28	2.30258509299405	NA	4.53604049151375	4.59592243604607	-0.059881944532318	1.75894296035721	0.814439434410513	0.0628989652270358	0.0340442787980783	0.0735253500779468	0.916724457134278	NA	NA	0.943489303385572	0.950515761556908	86.1202973786999
a10101	loss_cnaOV39	1022	AZD7762	CHEK1, CHEK2	10	21	0.693147180559945	NA	-0.683220333815368	-0.87839448122477	0.195174147409402	0.844427287982657	0.790980777886297	0.241568285401025	0.231131975703527	0.246749545457929	0.917073913008716	NA	NA	0.0805728605149132	0.547561256496677	86.1364131199373
a10102	PIK3CA_mut	230	GSK429286A	ROCK2	6	26	2.99573227355399	2.32630161961136	5.30107159576231	5.59359369177371	-0.292522096011406	0.797127330869446	1.01434783907779	0.298039207786007	0.366970350511436	0.288384403004553	0.917086345161259	NA	NA	0.30710841650152	0.462384443959952	86.1364131199373
a10103	loss_cnaOV81_(RB1)	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	4.97413265702095	4.93263275827265	0.0414998987483015	0.741326112807733	0.83391710717076	0.0502778754174918	0.0559806244934808	0.0497650166802534	0.917310701221266	NA	NA	0.946297110633538	0.922546982619099	86.1364131199373
a10104	PTEN_mut	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.38629436111989	NA	1.57441221207326	1.16663139462883	0.407780817444434	0.844796603018833	1.27639795543101	0.328535797301252	0.482697037354615	0.319477805263905	0.917335938521198	NA	NA	0.269736356414345	0.437302807215482	86.1364131199373
a10105	gain_cnaOV50	219	AT-7519	CDK9	4	28	2.32630161961136	NA	1.53109085836063	1.49293868430391	0.0381521740567168	0.996495265538021	1.78096593598604	0.022198175528115	0.0382863575735284	0.0214221806750019	0.917610160944205	NA	NA	0.319044318163497	0.951397073845	86.1364131199373
a10106	loss_cnaOV57_(ZNRF3)	333	T0901317	LXR	4	28	2.32630161961136	NA	5.00327798643195	4.71764800354882	0.285629982883131	1.17632183019981	1.11869593214575	0.253985563907922	0.242816188180927	0.255324056050932	0.917664554053405	NA	NA	0.0053550684009389	0.672452368629877	86.1364131199373
a10107	gain_cnaOV19	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	0	NA	-2.27074512389281	-1.96170853612151	-0.309036587771299	1.59677947389862	2.07521921759343	0.150916797721445	0.193537425062692	0.148917562612821	0.917775994844613	NA	NA	0.281118702304077	0.778680048107366	86.1364131199373
a10108	gain_cnaOV51_(MYC)	1012	Vorinostat	HDAC inhibitor Class I, IIa, IIb, IV	8	23	2.30258509299405	NA	1.44772077790617	1.39556555457387	0.0521552233322968	0.831376097790215	1.63225882658307	0.0352592769229562	0.0627336093386912	0.031952789890239	0.918050743934683	NA	NA	0.479228150432889	0.908620779694921	86.1364131199373
a10109	loss_cnaOV43_(NF1)	287	KIN001-244	PDPK1 (PDK1)	5	27	2.99573227355399	NA	3.55618407398519	3.54218537616581	0.013998697819376	0.744575082127951	0.934633715400352	0.0153564382703921	0.0188009217006948	0.0149777368275011	0.91819360776145	NA	NA	0.665208377958843	0.971589648107832	86.1364131199373
a10110	loss_cnaOV42	1091	BMS-536924	IGF1R	4	28	1.38629436111989	NA	2.32257761866426	2.40366990306397	-0.0810922843997099	1.21840485646599	0.915293977938224	0.0853632410752973	0.0665561073311213	0.0885969823404466	0.918373603662289	NA	NA	0.736368017089995	0.90512039839856	86.1364131199373
a10111	loss_cnaOV21, loss_cnaOV22	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	30	1.6094379124341	NA	1.05511187291177	1.17915008319669	-0.124038210284917	3.01004970568639	1.33963456579235	0.0824473478598162	0.0412080272463914	0.0925910792780661	0.918419882470343	NA	NA	0.81416459344479	0.949865407521807	86.1364131199373
a10112	gain_cnaOV26	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.37671286744998	2.36002085643919	0.0166920110107878	1.20237587069877	0.849935258685533	0.0190147676914059	0.0138825232754273	0.0196391558535915	0.918423925100207	NA	NA	0.610115754213485	0.983240047747839	86.1364131199373
a10113	loss_cnaOV52, loss_cnaOV53	203	BMS-345541	IKBKB	8	24	2.77258872223978	NA	3.36255890043381	3.24740156806154	0.115157332372272	1.24731949330657	0.980155356686749	0.109820098847645	0.0923238456467931	0.117488856829332	0.918703168998664	NA	NA	0.0938445859744718	0.816813315003075	86.1364131199373
a10114	gain_cnaOV26	225	Genentech Cpd 10	AURKA, AURKB	3	29	2.32630161961136	NA	3.06815171827775	2.82098017568509	0.247171542592663	2.12630800987155	1.84687066633145	0.132403755285518	0.116244467614828	0.13383262136251	0.918720156115899	NA	NA	0.349252239258304	0.861903312380672	86.1364131199373
a10115	TP53_mut	253	XMD14-99	EPHB3, CAMK1	22	10	2.32630161961136	NA	4.85999435994147	4.86021683654203	-0.000222476600550969	0.6575071133301	0.543571373204265	0.000355672734923455	0.000338363792635161	0.000409286823254702	0.918738925309172	NA	NA	0.0509812716604839	0.999209179769606	86.1364131199373
a10116	loss_cnaOV39	235	QL-XII-47	BTK, BMX	9	23	2.32630161961136	NA	1.80006052897706	1.4734216748155	0.326638854161554	1.37542060560226	1.71012252495275	0.200685884053889	0.237482885475986	0.191003188014601	0.919408581210443	NA	NA	0.0805824239050383	0.580726370245384	86.1364131199373
a10117	gain_cnaOV26	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.04014083165343	1.88643169079573	0.153709140857694	0.982108706540103	1.41396175895961	0.110569819041059	0.156509294576158	0.108708131520327	0.919441035990127	NA	NA	0.0352685391477339	0.821522293685029	86.1364131199373
a10118	gain_cnaOV96	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	1.82093126915115	1.51794766428868	0.302983604862471	1.67431175511976	1.62389947456286	0.185798449483663	0.180960089383592	0.186577808299391	0.919598609997763	NA	NA	0.0805826677517286	0.722828365637586	86.1364131199373
a10119	loss_cnaOV81_(RB1)	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	4	28	0.246860077931526	2.32630161961136	0.901315824666512	1.01887230876436	-0.117556484097852	1.48267590161042	1.57004990478116	0.0752827638683752	0.0792867031629548	0.0748743614708458	0.919702412870643	NA	NA	0.792259546516369	0.890036169496394	86.1364131199373
a10120	loss_cnaOV42	329	QL-XI-92	DDR1	4	28	2.32630161961136	NA	4.67118355868414	4.51403026457684	0.1571532941073	1.54107695020267	0.949503353941886	0.15344683745037	0.101976279696242	0.165511046859259	0.919874556169689	NA	NA	0.194015212158791	0.854056094240848	86.1364131199373
a10121	loss_cnaOV41	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.49235196940092	3.56731103032804	-0.0749590609271236	1.17421587791577	0.931492736062432	0.0774865984337961	0.0638375466870499	0.0804719758137755	0.919887677828539	NA	NA	0.730070708701586	0.897834538156199	86.1364131199373
a10122	gain_cnaOV96	299	OSI-027	MTORC1/2	5	27	2.99573227355399	NA	1.41393358019418	1.55274134315744	-0.13880776296326	0.8114954124339	2.05288486004587	0.071773597248272	0.171051814756336	0.0676159514178295	0.919901811912587	NA	NA	0.783901234431346	0.799191208034915	86.1364131199373
a10123	loss_cnaOV36	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.152184894364677	-0.10692977164295	-0.0452551227217275	1.40798497598109	1.25949973472894	0.0356256111755233	0.0321417653552684	0.035931029974744	0.91993969491476	NA	NA	0.768573222246973	0.961583998885434	86.1364131199373
a10124	loss_cnaOV54	277	ABT-869	VEGFR and PDGFR family	10	22	0.0237165266173161	NA	2.75885883445602	2.69657088091623	0.0622879535397893	0.530253773913334	0.590867636491706	0.108637350390742	0.11746819467233	0.105417778353247	0.91994704307298	NA	NA	0.137930449558974	0.769631763499606	86.1364131199373
a10125	loss_cnaOV58	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.79306539689373	2.74086198001335	0.0522034168803782	0.886984528754826	1.78576023224579	0.0308219712068599	0.058854935106549	0.0292331612820869	0.920138590253191	NA	NA	0.324242128391231	0.922514398649411	86.1364131199373
a10126	gain_cnaOV94	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	7	26	-1.38629436111989	0.693147180559945	-2.06167374159946	-2.36194943725152	0.300275695652062	2.0062306338684	1.51777232680582	0.184919260155386	0.149671573438729	0.197839748655846	0.920220569072088	NA	NA	0.126495689660225	0.722044733788014	86.1364131199373
a10127	gain_cnaOV51_(MYC)	274	PXD101, Belinostat	HDAC	7	23	2.99573227355399	NA	0.662395358390108	0.913308068345692	-0.250912709955584	1.37321169490448	2.24795026988609	0.119965863939423	0.182719613360879	0.11161844339568	0.92048369085106	NA	NA	0.419013872900498	0.724245741285818	86.1364131199373
a10128	loss_cnaOV20	151	QS11	ARFGAP	4	15	2.32630161961136	NA	3.91734013683528	3.72662996685013	0.19071016998515	1.80542583848268	1.3955356881976	0.129193177301676	0.105631683074519	0.136657322057784	0.92050123260876	NA	NA	0.0673744742106885	0.853987602676993	86.1364131199373
a10129	gain_cnaOV95_(MECOM)	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	1.91108971361989	1.84275041333605	0.0683393002838351	1.34367675013373	1.78018837232909	0.0404933353750912	0.0508599261519065	0.0383888027503652	0.920528273779326	NA	NA	0.351158543276227	0.930814839371612	86.1364131199373
a10130	loss_cnaOV85	263	FR-180204	ERK	7	25	2.99573227355399	NA	4.82163159113434	4.80900265699653	0.0126289341378119	0.669459523900983	0.772955463269467	0.0167627099831586	0.0188643729559963	0.0163385016833876	0.920590886821478	NA	NA	0.76660890808986	0.966795654812331	86.1364131199373
a10131	loss_cnaOV43_(NF1)	1114	Cetuximab	EGFR	4	28	4.18661983833127	NA	5.70470960746493	5.83919527736326	-0.134485669898335	1.3275632061284	1.29289010046268	0.10373785778154	0.101302649303259	0.104019413444505	0.920655542864745	NA	NA	0.573316549763437	0.858782112291039	86.1364131199373
a10132	gain_cnaOV95_(MECOM)	1003	Camptothecin	TOP1	8	23	-2.30258509299405	NA	-3.70780585820048	-3.68538079211704	-0.0224250660834349	1.50844860620841	1.81197981017753	0.0128616663299619	0.0148663109841056	0.0123760021814138	0.920776335316029	NA	NA	0.24813004818208	0.973093530796406	86.1364131199373
a10133	gain_cnaOV18_(CCNE1)	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.36820593343983	4.17257750401177	0.195628429428058	1.09662824082743	0.965684091217491	0.199709186107529	0.178390836698179	0.202580151425523	0.920792414178794	NA	NA	0.0494383504101808	0.753313519560948	86.1364131199373
a10134	loss_cnaOV39	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-3.58593190837398	-3.41027927257014	-0.175652635803848	2.386720784011	1.56219048903693	0.0980923756425828	0.0735958043272473	0.112439959810622	0.920901231808007	NA	NA	0.684710411772358	0.883881774980255	86.1364131199373
a10135	gain_cnaOV96	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	1.8435454823264	1.65399022555853	0.189555256767867	1.27500546322278	1.52566272701297	0.126820600458784	0.148670152588003	0.124244535447877	0.920923053536267	NA	NA	0.329370751909155	0.77702176593217	86.1364131199373
a10136	loss_cnaOV34	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.15280651447023	5.04518941191469	0.107617102555538	0.668856177217604	0.613719191696832	0.17319785787427	0.160897224577065	0.175352350083748	0.920952934600624	NA	NA	0.112689639742188	0.750683193518295	86.1364131199373
a10137	loss_cnaOV16, loss_cnaOV17	309	Y-39983	ROCK	6	26	2.99573227355399	NA	5.08480592045821	4.93647813676246	0.148327783695752	1.73218468329716	1.12388866288595	0.119036798737755	0.085630467193264	0.131977293297782	0.921052679556783	NA	NA	0.375499378050594	0.847892636799682	86.1364131199373
a10138	gain_cnaOV95_(MECOM)	304	SB52334	ALK5	9	23	2.99573227355399	NA	4.32886039690604	4.38142398572291	-0.0525635888168727	1.16929304175668	1.03282870280243	0.0490826095171579	0.0449533067757798	0.0508928428056357	0.921102250990089	NA	NA	0.354744629932767	0.907815737315132	86.1364131199373
a10139	loss_cnaOV82	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-3.00351110140998	-3.34858200217715	0.345070900767174	2.39506751478884	1.786808544969	0.188024833837661	0.144075646567982	0.193121362520213	0.921128641015091	NA	NA	0.141899816277887	0.82883062209981	86.1364131199373
a10140	loss_cnaOV1	1262	UNC1215	LMBL3	3	30	0	NA	2.86540833944542	2.77191314104894	0.0934951983964822	0.328855519519977	0.507625322272304	0.187729294331449	0.284304786895337	0.18418151005148	0.921147969958761	NA	NA	0.111745597209698	0.687574044931591	86.1364131199373
a10141	loss_cnaOV40	292	Masitinib	KIT	7	25	2.99573227355399	NA	4.09442011794142	3.99086850506124	0.103551612880187	1.2262375532672	1.0114216494306	0.0978859458639539	0.084446616892692	0.102382238840234	0.921390468770847	NA	NA	0.106746895533499	0.842610874737502	86.1364131199373
a10142	loss_cnaOV39	1003	Camptothecin	TOP1	10	21	-2.30258509299405	NA	-3.57294084682525	-3.74746650552587	0.174525658700624	2.16174575723824	1.51489644086829	0.100213042670926	0.0807336654258505	0.115206329615899	0.921635768059436	NA	NA	0.248131845610919	0.821695392839338	86.1364131199373
a10143	loss_cnaOV81_(RB1)	261	TL-1-85	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	3.57776649478722	3.55243184595403	0.0253346488331925	0.885818487981329	0.97642987829562	0.0261789028500202	0.0286002710227092	0.0259462040197036	0.921784782661284	NA	NA	0.730072865093337	0.960352877015938	86.1364131199373
a10144	loss_cnaOV1	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.150430562102551	-0.107117735813892	-0.0433128262886583	1.39366886598254	1.26068547506551	0.0340964321921104	0.0310782764441844	0.034356568030109	0.9219097016683	NA	NA	0.768575232439607	0.962873509136972	86.1364131199373
a10145	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	3.93615919110906	3.91672259597288	0.0194365951361823	0.846859510240137	1.28259189641588	0.0157804303242184	0.0229513808384473	0.0151541540146142	0.921970910247374	NA	NA	0.700578090921524	0.966940722453039	86.1364131199373
a10146	NF1_mut	1175	AG-014699	PARP1, PARP2	4	29	1.6094379124341	NA	3.79888217263249	3.91526493380626	-0.116382761173773	0.787211093842883	1.10972734024473	0.107490806352052	0.147841871238925	0.104875095848416	0.922023387597971	NA	NA	0.319253495231731	0.804157147475736	86.1364131199373
a10147	gain_cnaOV72_(ASXL1)	329	QL-XI-92	DDR1	5	27	2.32630161961136	NA	4.52056184471287	4.53610268219718	-0.0155408374843136	1.29701107095573	0.977108243227224	0.0151537526162455	0.0119820391917411	0.0159049292563379	0.922055591987614	NA	NA	0.194019351920286	0.980676601324537	86.1364131199373
a10148	ARID1A_mut	1031	Elesclomol	HSP70	9	22	-1.6094379124341	NA	-4.03965133750506	-4.06800448969425	0.0283531521891929	1.33478621089009	1.60792264066919	0.0184419257583393	0.0212417179304586	0.0176334056577453	0.922063758258009	NA	NA	0.864943769553245	0.960298914139486	86.1364131199373
a10149	loss_cnaOV58	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	3.07414829904485	3.28390410253482	-0.209755803489962	1.34093095021251	1.04974391916251	0.19189779997067	0.156425506814292	0.19981616436255	0.922161237536989	NA	NA	0.0639142171726518	0.75386022387202	86.1364131199373
a10150	gain_cnaOV94	180	Thapsigargin	sarco-endoplasmic reticulum Ca2+-ATPases	3	16	-0.669430653942629	NA	-4.16039746239939	-3.94909618036141	-0.211301282037975	1.67935303202353	1.86137960904885	0.114781563768259	0.125823027087621	0.113518640158494	0.922425781208447	NA	NA	0.594533760195565	0.856770968389625	86.1364131199373
a10151	loss_cnaOV20	1050	ZM-447439	AURKB	5	17	1.38629436111989	0.693147180559945	2.61559436491733	2.39929430869618	0.216300056221148	1.90966120630479	1.51042324946654	0.135333946846709	0.113266193766218	0.143204930338262	0.922449714672736	NA	NA	0.231723377183941	0.824275770019314	86.1364131199373
a10152	loss_cnaOV54	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	6	13	0.940007258491471	NA	2.36533097369746	2.41454428514309	-0.0492133114456341	0.715931529554718	1.09473521085347	0.049294377526129	0.0687402487724531	0.0449545341720274	0.922676522978824	NA	NA	0.415287782645823	0.908635978099113	86.1364131199373
a10153	loss_cnaOV35	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	0	NA	-2.23571548280779	-1.94588978718874	-0.289825695619056	2.65187904875307	1.94139291284637	0.141587469576517	0.109290691728695	0.149287500588496	0.922730225455068	NA	NA	0.281128692202621	0.825036507797033	86.1364131199373
a10154	loss_cnaOV57_(ZNRF3)	1052	RO-3306	CDK1	4	29	1.6094379124341	NA	3.54154118100563	3.47354765741484	0.0679935235907951	1.25277618422077	0.867806118947971	0.0745387950795147	0.0542742785560591	0.0783510534279508	0.922766925959099	NA	NA	0.795410618179109	0.922163865639107	86.1364131199373
a10155	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	4.01265715744873	3.87128857549801	0.141368581950719	0.808329489038593	1.64727218294181	0.0881587897932441	0.174889799107613	0.0858198076885228	0.922936843219987	NA	NA	0.717332869927275	0.813128943389464	86.1364131199373
a10156	loss_cnaOV56	1053	MK-2206	AKT1, AKT2	3	29	1.38629436111989	0.693147180559945	1.40081250150489	1.30048596671107	0.100326534793817	1.4047140296256	1.21389513414139	0.0817297763586883	0.0714213232572023	0.0826484364028527	0.92296083411465	NA	NA	0.0994922597769887	0.914664610647068	86.1364131199373
a10157	KRAS_mut	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	0.92244517122787	1.22491436367267	-0.302469192444798	0.148094955046801	1.70015780567963	0.189300243670851	2.04240037987257	0.177906539871978	0.923163055645605	NA	NA	0.539037920661007	0.495384405053649	86.1364131199373
a10158	PTEN_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.61341744481865	5.72558955126737	-0.112172106448724	0.123278647574258	0.496509248755066	0.233337771944865	0.909907016794256	0.225921484302621	0.923268805418239	NA	NA	0.384624303307915	0.354618606573127	86.1364131199373
a10159	gain_cnaOV4_(KRAS)	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	3.64798603966746	3.6908222500196	-0.0428362103521449	1.05893454408076	1.06214689599062	0.040354216087186	0.0404521795908831	0.0403298362155392	0.923350840856453	NA	NA	0.832008327368262	0.926614490208479	86.1364131199373
a10160	gain_cnaOV94	222	BX-912	PDPK1 (PDK1)	7	25	2.32630161961136	NA	3.53058932891469	3.3761289939425	0.15446033497219	1.15943815001788	1.24660427663353	0.125611672471344	0.133219986740826	0.123904865294792	0.923419831411294	NA	NA	0.329689596998894	0.765469465721927	86.1364131199373
a10161	loss_cnaOV85	272	AR-42	HDAC	7	23	1.63315443905142	NA	0.259574552970523	0.305909190301521	-0.0463346373309989	1.64530238256788	1.91381443660274	0.0249172174466389	0.0281617761099226	0.0242106217012599	0.923513115022668	NA	NA	0.488925424601776	0.95108212792721	86.1364131199373
a10162	gain_cnaOV49	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	2.46587213241378	2.37043779727407	0.0954343351397036	0.780426750781664	1.34650902240737	0.0724442432407456	0.122284807695428	0.070875377403027	0.923532882886764	NA	NA	0.112080777869237	0.863206612657744	86.1364131199373
a10163	loss_cnaOV84	1091	BMS-536924	IGF1R	6	26	1.38629436111989	NA	2.40211305409203	2.39155343984215	0.0105596142498761	1.29902564247804	0.863904349636693	0.0111111559876477	0.00812887282943268	0.0122231289312489	0.923767754849853	NA	NA	0.736373999519363	0.985476378402867	86.1364131199373
a10164	gain_cnaOV96	255	CP724714	ERBB2	5	27	2.32630161961136	NA	4.43540979669127	4.4113028395962	0.0241069570950767	0.645202858412146	0.997691541958866	0.0251582076524559	0.0373633761549108	0.0241627357567301	0.923897919643629	NA	NA	0.787738288350247	0.946237914273692	86.1364131199373
a10165	loss_cnaOV21, loss_cnaOV22	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.25824019289268	3.33212137197254	-0.0738811790798555	1.16331313543746	1.24581687092548	0.0595581883125403	0.0635092795131835	0.059303402292964	0.923951689529685	NA	NA	0.993650939400222	0.924929199688974	86.1364131199373
a10166	loss_cnaOV58	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	5	28	-2.30258509299405	NA	-0.403586935707812	-0.31988445937794	-0.0837024763298723	1.82864715985928	1.34700360242082	0.0590130849865868	0.0457728960333241	0.062139756849531	0.924036411725548	NA	NA	0.88962926775553	0.926093661851446	86.1364131199373
a10167	loss_cnaOV83	273	CUDC-101	HDAC, EGFR	5	26	1.63315443905142	NA	0.0974878145704749	0.122032922806308	-0.0245451082358326	1.06519245708001	1.71077022704154	0.014994574043133	0.0230428858866665	0.0143474020343918	0.924186856709631	NA	NA	0.4647133748449	0.967358608260079	86.1364131199373
a10168	loss_cnaOV42	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.35749470169474	3.29457640518487	0.0629182965098645	0.74456370598929	1.14979705296493	0.0563826699944989	0.0845035770663384	0.0547212191469961	0.924272935797249	NA	NA	0.951228160673075	0.889317925656266	86.1364131199373
a10169	gain_cnaOV49	344	THZ-2-49	CDK9	3	29	2.99573227355399	NA	2.8487321167561	2.56018369605827	0.288548420697837	1.48869885117881	2.40185513698143	0.122680394036359	0.193825917491205	0.120135646923517	0.924379312283831	NA	NA	0.388869998608508	0.783995835025074	86.1364131199373
a10170	loss_cnaOV56	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.0140654439901803	-0.121728284183075	0.107662840192894	1.50436215855149	1.25083589719518	0.0847774669944774	0.071567102097649	0.0860727138022765	0.924470965702731	NA	NA	0.768577770103328	0.914417111424146	86.1364131199373
a10171	gain_cnaOV19	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.766476794829566	0.811182842123796	-0.0447060472942299	0.305583499084761	1.16163764148833	0.0411215921499616	0.146297321118866	0.0384853638497381	0.92450218908665	NA	NA	0.361344293454853	0.902205798840127	86.1364131199373
a10172	PTEN_mut	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	4.98367103349763	4.93131712013793	0.0523539133596911	0.551911820845405	0.84943235576026	0.0634330873779434	0.0948591992095706	0.0616339994640694	0.924599227026607	NA	NA	0.946298766048155	0.8753609348783	86.1364131199373
a10173	loss_cnaOV1	273	CUDC-101	HDAC, EGFR	3	28	1.63315443905142	NA	-0.0521995710075914	0.136317634958541	-0.188517205966132	1.64707709127321	1.63511706658184	0.115234460932249	0.114455605608846	0.115292788399684	0.924601875936785	NA	NA	0.464714172098148	0.864992829916796	86.1364131199373
a10174	gain_cnaOV95_(MECOM)	1019	Bosutinib	SRC, ABL, TEC	8	23	0.693147180559945	NA	1.82503274991368	1.68817820887594	0.136854541037746	1.98438410425363	1.47296586728445	0.0849320152269046	0.0689657515117115	0.0929108705621605	0.924657305597303	NA	NA	0.0424425820441072	0.861810326191279	86.1364131199373
a10175	gain_cnaOV50	228	KIN001-102	AKT1	4	28	2.32630161961136	NA	2.87353252316224	2.77676418458927	0.0967683385729767	1.07810682875062	1.25500196986667	0.0781366540248028	0.0897576529453192	0.0771061248479612	0.92467335975012	NA	NA	0.096738991594458	0.876994824438512	86.1364131199373
a10176	loss_cnaOV43_(NF1)	269	NSC-207895	MDM4	5	26	2.99573227355399	NA	3.98872475634429	3.86501645402189	0.123708302322398	1.49848387352458	1.61962472163655	0.0771508572358025	0.0825556447473964	0.0763808434569935	0.924825856758746	NA	NA	0.71733509975382	0.873042274372305	86.1364131199373
a10177	loss_cnaOV40	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	8.7998779957866	8.74515086366173	0.0547271321248761	1.50349600887434	1.77619361581115	0.0317568490461335	0.036399918457948	0.0308114676450311	0.924833817068954	NA	NA	0.922291802253685	0.936701859920454	86.1364131199373
a10178	KRAS_mut	1166	QL-VIII-58	MTOR, ATR	6	17	2.30258509299405	NA	-1.54213092233854	-1.04867351178705	-0.493457410551488	0.967908489409131	1.41856275245603	0.372353865356244	0.509818248265105	0.347857301129004	0.924891275388759	NA	NA	0.0511591343824513	0.363327245908932	86.1364131199373
a10179	loss_cnaOV33_(ZFHX3)	219	AT-7519	CDK9	4	28	2.32630161961136	NA	1.53846368672727	1.49188542310867	0.0465782636185923	1.43902752434845	1.74699509149573	0.0271011305340361	0.0323678754092501	0.0266619315906109	0.924909903951618	NA	NA	0.319059482151088	0.955672651975721	86.1364131199373
a10180	gain_cnaOV50	256	JW-7-24-1	LCK	4	28	2.32630161961136	NA	2.01852580782813	1.9280325488614	0.0904932589667267	1.32007690664631	1.35621479699622	0.0669009942885638	0.0685515052275455	0.0667248721715419	0.92496092182429	NA	NA	0.840028012798634	0.904525507800166	86.1364131199373
a10181	loss_cnaOV87, loss_cnaOV88	1023	GW 441756	NTRK1	3	28	0.693147180559945	NA	2.3449533792317	2.2934881289346	0.0514652502970971	1.59335020917504	1.23967272514464	0.0406121660771684	0.0323000241884948	0.0415151912704158	0.925026369154908	NA	NA	0.845497644896435	0.961170058310132	86.1364131199373
a10182	gain_cnaOV4_(KRAS)	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.44312830758047	3.66308458447778	-0.219956276897305	0.811298835276686	0.928660088085525	0.241175054551787	0.271116224174402	0.236853375868403	0.925032808990398	NA	NA	0.0620438887789359	0.653636325087843	86.1364131199373
a10183	loss_cnaOV35	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	1.19994624328175	1.16214667493669	0.0377995683450671	2.09262698188849	1.39687944325478	0.0251186889095951	0.0180632136889274	0.0270600075959259	0.925090424109691	NA	NA	0.814169690907569	0.97060179770844	86.1364131199373
a10184	loss_cnaOV33_(ZFHX3)	1021	Axitinib	PDGFR, KIT, VEGFR	4	26	0.693147180559945	NA	2.59160622379205	2.51507545777012	0.0765307660219277	0.55953433088683	1.09134499434808	0.0730700200374386	0.136775818385676	0.0701251816962275	0.925124847773759	NA	NA	0.198571190010563	0.833997739549092	86.1364131199373
a10185	SMAD4_mut	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-2.59134487957683	-2.74675242323609	0.155407543659257	1.15701240990217	1.81915391794901	0.0871763987111293	0.134317957464603	0.0854284742626234	0.925171734173956	NA	NA	0.698045621006944	0.848279088172942	86.1364131199373
a10186	gain_cnaOV26	163	JQ1	BRD4	3	16	0.940007258491471	NA	-0.0921496150905095	0.122384993191002	-0.214534608281512	2.96527323988537	1.69300253621682	0.113647211573392	0.0723490184296828	0.126718421084537	0.925231875520193	NA	NA	0.586138607001636	0.913183273278079	86.1364131199373
a10187	gain_cnaOV51_(MYC)	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.10552771930457	2.15288958242235	-0.0473618631177839	1.13828110042462	1.45065768947704	0.0343397899454048	0.0416082311303562	0.0326485451815016	0.925257327916143	NA	NA	0.893528633437187	0.94335066346355	86.1364131199373
a10188	PTEN_mut	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.08607857586098	4.53271198132909	-0.446633405468112	0.683155721008448	0.667361140404819	0.668150375027697	0.65377979241513	0.669252940315322	0.925296126527827	NA	NA	0.0548598997492284	0.376144924853598	86.1364131199373
a10189	gain_cnaOV50	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.33457933343821	2.29311890422633	0.0414604292118717	1.27903796705485	1.26588662101774	0.0327167621653574	0.0324153232975089	0.0327520873698298	0.925301189485833	NA	NA	0.845497825016394	0.954650224535168	86.1364131199373
a10190	gain_cnaOV49	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-1.18755566154575	-1.33083113023517	0.143275468689417	0.429327947791965	1.94965511636194	0.0759354956491471	0.333720339955233	0.0734875965944016	0.925399095798123	NA	NA	0.0758332482944465	0.748580632058786	86.1364131199373
a10191	loss_cnaOV84	300	CX-5461	RNA Pol I	6	25	2.32630161961136	NA	3.64588493976155	3.51384313742733	0.13204180233422	2.16867404831769	1.61421471899276	0.0766530188137974	0.060885960449727	0.0817994042432049	0.925421445919962	NA	NA	0.700361450404078	0.892879392871172	86.1364131199373
a10192	loss_cnaOV102	271	VNLG/124	HDAC, RAR 	3	28	1.63315443905142	NA	4.40671181960039	4.32106646089216	0.0856453587082244	0.608482238462315	0.590540991278682	0.144721137639924	0.140752438271094	0.145028643181532	0.925473897366023	NA	NA	0.257004091689398	0.834465928136476	86.1364131199373
a10193	KRAS_mut	222	BX-912	PDPK1 (PDK1)	7	25	2.32630161961136	NA	3.26758854463409	3.44976921354106	-0.182180668906974	0.892772811636954	1.29950345062802	0.148238069156837	0.204061622993351	0.140192524166773	0.925632334684473	NA	NA	0.329694000560539	0.675354549501765	86.1364131199373
a10194	gain_cnaOV18_(CCNE1)	1133	JNJ-26854165	MDM2	4	29	2.30258509299405	NA	3.10864733854918	3.06223025162075	0.0464170869284319	1.14275234647223	0.899727710838898	0.050124396464187	0.0406186756664514	0.0515901492965611	0.925720112348974	NA	NA	0.241621284971571	0.942063008993776	86.1364131199373
a10195	loss_cnaOV70	1243	piperlongumine	Increases ROS levels	3	29	2.30258509299405	NA	1.71557638691734	1.60401538658171	0.111561000335628	0.48390377519882	0.700852121852409	0.162030405482583	0.2305437693471	0.15917908622544	0.925865615095111	NA	NA	0.211807529398708	0.741730826873403	86.1364131199373
a10196	NF1_mut	1038	NU-7441	PRKDC (DNAPK)	4	29	0.693147180559945	NA	2.44823224199223	2.549294576981	-0.101062334988772	0.709952592979324	1.072708374249	0.0968836486632282	0.142350821714255	0.0942123110202488	0.925888972156144	NA	NA	0.397922918405089	0.813546074002563	86.1364131199373
a10197	ARID1A_mut	224	AS605240	PI3Kgamma	8	24	2.99573227355399	2.32630161961136	3.57748683411117	3.3076391506761	0.269847683435068	1.3920271687782	1.75611263283156	0.160792147128078	0.193852310851029	0.153661945361651	0.925954113073549	NA	NA	0.631872250785571	0.663904221441071	86.1364131199373
a10198	loss_cnaOV42	262	VX-11e	ERK	4	28	1.63315443905142	NA	2.74447465488249	2.87567800621408	-0.131203351331597	1.33603782567974	1.10325155002118	0.116243639377324	0.0982033209013708	0.118924239289832	0.926000032534871	NA	NA	0.393668783756707	0.861339244636549	86.1364131199373
a10199	loss_cnaOV56	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-1.03062045667374	-1.1994186932195	0.168798236545757	1.62006770267449	1.31063787970458	0.125670405412139	0.104192087939965	0.128790903391107	0.926006936282211	NA	NA	0.0511605573591936	0.87668185406462	86.1364131199373
a10200	loss_cnaOV38	1005	Cisplatin	DNA crosslinker	8	23	1.79175946922805	2.30258509299405	3.15216918314633	2.97883764776029	0.173331535386041	1.26116969575423	1.17997078150387	0.144434081846001	0.137437123623861	0.146894769008713	0.926505514144008	NA	NA	0.0905102985029461	0.739689583623888	86.1364131199373
a10201	loss_cnaOV87, loss_cnaOV88	1058	GDC0941	PI3K (class 1)	3	30	1.38629436111989	0.693147180559945	1.05099756984867	0.823158443143121	0.22783912670555	1.29680752040996	1.35875130880668	0.168166764439479	0.175692323740938	0.167682728420441	0.926575241163085	NA	NA	0.165755755001874	0.795252635364131	86.1364131199373
a10202	gain_cnaOV94	1264	SGC0946	Q8TEK3 (DOT1L)	7	26	-0.693147180559945	NA	2.21447791833004	2.08861367974307	0.125864238586971	0.54138611476069	0.565748932056576	0.224310506639991	0.232485161985742	0.222473665357947	0.926593378818466	NA	NA	0.0434877039207523	0.600719415529915	86.1364131199373
a10203	gain_cnaOV72_(ASXL1)	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	2.59403284203024	2.58597627132618	0.00805657070406296	2.39477967908814	2.34724131268403	0.00342303283496344	0.00336422209291949	0.00343235723592918	0.926686196891333	NA	NA	0.388874456765403	0.994713171259077	86.1364131199373
a10204	gain_cnaOV96	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.41320004530425	3.50093098456308	-0.087730939258833	0.672766324262702	1.16378025795913	0.0781229025760941	0.130403285799091	0.0753844539455266	0.926850435566477	NA	NA	0.728473224556047	0.835205689560451	86.1364131199373
a10205	loss_cnaOV70	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.4528633231616	3.4846818939856	-0.0318185708239964	1.31546999533599	0.877837479726471	0.0348724096600344	0.0241879867551593	0.0362465394322317	0.926906967645745	NA	NA	0.795413948259121	0.970748521315007	86.1364131199373
a10206	loss_cnaOV20	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.44148347772865	-3.46050902979582	0.0190255520671667	2.56502796644139	1.57855894081798	0.0106137792332264	0.00741728835555813	0.012052481269599	0.926968869763238	NA	NA	0.68472436960472	0.989462621044835	86.1364131199373
a10207	loss_cnaOV1	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.24226317784802	3.0001367796469	0.242126398201115	0.86731391839702	1.22141582075015	0.20171260621523	0.279168122481668	0.198234208275122	0.927036727639876	NA	NA	0.0905109825668738	0.690927676241326	86.1364131199373
a10208	loss_cnaOV54	173	FH535	unknown 	5	13	3.46573590279973	NA	2.26068139944268	2.58765138340801	-0.326969983965328	0.72081596391843	1.62446865893781	0.22514516373869	0.453610908099046	0.201278111563644	0.927092201321745	NA	NA	0.125334868827297	0.563636571078527	86.1364131199373
a10209	gain_cnaOV94	1023	GW 441756	NTRK1	7	24	0.693147180559945	NA	2.24008168581997	2.3154981644635	-0.0754164786435267	1.62104356560743	1.1568412497731	0.0595276309524802	0.0465234125988878	0.0651917267458421	0.927131065636914	NA	NA	0.84549900727172	0.911436915264038	86.1364131199373
a10210	KRAS_mut	268	YM155	BIRC5 (Survivin)	7	23	1.63315443905142	NA	-4.06210411463246	-4.17826087903644	0.116156764403986	2.06392742810076	2.44242669419671	0.0490854050074048	0.0562794809655075	0.0475579327232127	0.927266435967187	NA	NA	0.928519884167779	0.902903941259426	86.1364131199373
a10211	PIK3R1_mut	164	JQ12	HDAC	3	16	1.63315443905142	NA	2.0741474343126	1.74134536180666	0.332802072505944	2.60847047814044	2.18664554457155	0.148545957611233	0.127585140523881	0.152197539894905	0.927355225608795	NA	NA	0.663944276396194	0.85086620577181	86.1364131199373
a10212	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1161	ZG-10	IRAK1	6	17	2.30258509299405	NA	1.57781554269264	1.57755011383138	0.000265428861257577	1.23971193641981	1.281966420242	0.000208665050814878	0.000214105271926407	0.000207048216760211	0.927475385057751	NA	NA	0.1675325064755	0.999653119106465	86.1364131199373
a10213	loss_cnaOV39	309	Y-39983	ROCK	9	23	2.99573227355399	NA	5.00799544500272	4.9471873075456	0.0608081374571157	1.49986420711416	1.14151130694395	0.0487564733200228	0.0405424285536586	0.0532698511939499	0.927485225604161	NA	NA	0.375512097540585	0.914397506129455	86.1364131199373
a10214	PIK3CA_mut	1017	Olaparib	PARP1, PARP2	7	24	1.6094379124341	NA	3.59105368657073	4.0800566087979	-0.489002922227169	1.4170509578792	1.08045217569921	0.42222850256761	0.34508492408701	0.452590992202606	0.927497148118178	NA	NA	0.0847391242754513	0.422636550194807	86.1364131199373
a10215	gain_cnaOV94	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	24	2.30258509299405	NA	2.163690124521	2.16766391221079	-0.00397378768979362	1.154570523442	1.351402375153	0.00302626086057475	0.00344178862105969	0.00294049186449278	0.927650444908588	NA	NA	0.688425591395261	0.993992995712726	86.1364131199373
a10216	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1502	Bicalutamide	ANDR (androgen receptor)	4	28	2.30258509299405	NA	4.56552699778762	4.5091159351121	0.0564110626755214	0.413928834094274	0.621316409208172	0.09342802412681	0.136282032149211	0.0907928099748946	0.927654550924688	NA	NA	0.61722960596287	0.821691092989706	86.1364131199373
a10217	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1026	17-AAG	HSP90	8	25	0	NA	-0.53808609754732	-0.528510897727722	-0.00957519981959809	2.55300624683349	2.2416006392411	0.00413511673437251	0.00375055871150894	0.00427159042158367	0.927661723804677	NA	NA	0.062757958472178	0.992594546721867	86.1364131199373
a10218	gain_cnaOV50	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	1.6094379124341	NA	1.22152764547611	1.3574340674961	-0.13590642201999	1.0556200013143	1.39371290974404	0.0997380632301052	0.128745592022489	0.0975139292101049	0.92777149738908	NA	NA	0.583258009026201	0.828066493860243	86.1364131199373
a10219	loss_cnaOV52, loss_cnaOV53	257	NPK76-II-72-1	PLK3	8	24	2.32630161961136	NA	3.23949578615802	3.22643398046799	0.0130618056900227	1.05432522551631	1.29264138315001	0.0105240893910467	0.012388782297821	0.0101047404642057	0.927780883168163	NA	NA	0.603166294029071	0.977569035607177	86.1364131199373
a10220	gain_cnaOV72_(ASXL1)	305	TPCA-1	IKK	5	27	2.99573227355399	NA	3.37275639569513	3.3163873476817	0.0563690480134298	1.59205021287729	1.17714134597722	0.0454403440058393	0.0354065767257144	0.0478863886703719	0.9277898182267	NA	NA	0.993651039520274	0.942877650147307	86.1364131199373
a10221	loss_cnaOV55	1004	Vinblastine	Microtubules	7	24	-2.30258509299405	NA	-3.15404096990503	-3.36218927399396	0.208148304088925	1.43483561652778	1.92704460342835	0.113366444538923	0.145067700920772	0.108014263768786	0.928047526325591	NA	NA	0.14191130793892	0.760948635827328	86.1403563791786
a10222	loss_cnaOV82	1042	BIRB 0796	p38, JNK2	3	30	2.30258509299405	NA	4.43058214483108	4.39419020661641	0.0363919382146705	1.42102404868549	0.815584329542937	0.0419507826430063	0.0256096568163886	0.0446206932826492	0.928088328778268	NA	NA	0.870292977669865	0.96893153013557	86.1403563791786
a10223	gain_cnaOV95_(MECOM)	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	2.76439677478205	2.68917775752996	0.0752190172520888	1.25462505442816	1.37786146900373	0.0557228580742048	0.0599533836715644	0.0545911319419334	0.928104649551938	NA	NA	0.941788540244418	0.913612052001832	86.1403563791786
a10224	gain_cnaOV94	1006	Cytarabine	DNA synthesis	7	24	0.693147180559945	NA	-0.0432384155005178	-0.131163307524709	0.0879248920241909	1.61542558208727	1.16286876974521	0.0692428833013745	0.0544283147420413	0.0756103305134385	0.92828838979825	NA	NA	0.76858139343487	0.896585107311443	86.1489829214923
a10225	loss_cnaOV38	222	BX-912	PDPK1 (PDK1)	8	24	2.32630161961136	NA	3.45813851867824	3.3938434167308	0.0642951019474403	1.2750949487183	1.21739055636766	0.0522258677730348	0.0504237759016051	0.0528138661920281	0.92839458958426	NA	NA	0.329699315045484	0.902744572097786	86.1504124064034
a10226	gain_cnaOV95_(MECOM)	272	AR-42	HDAC	8	22	1.63315443905142	NA	0.340646881336403	0.278534463501701	0.0621124178347017	1.1720258155224	2.03767586694616	0.0334038966697125	0.052995776212503	0.0304819911950907	0.928514391342854	NA	NA	0.488934923828297	0.918537463484993	86.1531036838861
a10227	PIK3CA_mut	166	FTI-277	Farnesyl transferase (FNTA)	5	14	0.0237165266173161	NA	2.3739809763127	2.47095762467503	-0.0969766483623333	0.513098758029807	0.942191287992767	0.112672628943285	0.189001915995087	0.102926708830997	0.928922736043056	NA	NA	0.625777582037649	0.780247103395756	86.1825645524518
a10228	gain_cnaOV4_(KRAS)	1175	AG-014699	PARP1, PARP2	7	26	1.6094379124341	NA	3.93836713683014	3.89114006973463	0.0472270670955064	1.2907703312358	1.02722423554384	0.0435976164198659	0.0365882806202174	0.0459754213942422	0.929088535435045	NA	NA	0.319266899585314	0.930860518135503	86.1884770053159
a10229	loss_cnaOV34	1248	FK866	NAMPT	5	27	0	NA	-1.1943787024716	-1.8035390541939	0.609160351722306	3.83371642912378	2.56889702714191	0.219826331591505	0.158895516396223	0.237129143475261	0.92916813699683	NA	NA	0.0458205638824849	0.74757462646614	86.1884770053159
a10230	gain_cnaOV72_(ASXL1)	282	EKB-569	EGFR	5	27	0.916290731874155	2.99573227355399	1.67877966853499	1.68450241329768	-0.00572274476269685	1.3953139165285	1.51130629005152	0.00382444324259483	0.00410140305698009	0.00378662141510823	0.929390505039716	NA	NA	0.329387462713267	0.993642373053622	86.1909209178
a10231	loss_cnaOV40	165	DMOG	Prolyl-4-Hydroxylase	4	15	8.29404964010203	NA	6.51884086122818	6.74532200741033	-0.226481146182144	0.65003190382614	1.66138200097269	0.147813497033993	0.348415431379688	0.136320934047405	0.929444260640125	NA	NA	0.342294173633097	0.680428129553209	86.1909209178
a10232	gain_cnaOV96	184	BMS-754807	IGF1R	4	13	0.940007258491471	NA	0.754177644777155	0.818406122701017	-0.0642284779238618	0.336766207280267	1.20350437899243	0.0590915489192175	0.190721267559987	0.0533678805370313	0.929536257257766	NA	NA	0.361364301043316	0.865891981528691	86.1909209178
a10233	loss_cnaOV85	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	-0.0799185813974005	-0.0587334032047218	-0.0211851781926787	1.09503450423357	0.939145019008055	0.0217881783433985	0.0193465850717705	0.0225579412805223	0.929562145335066	NA	NA	0.551401009753162	0.963883479149557	86.1909209178
a10234	loss_cnaOV39	1161	ZG-10	IRAK1	7	16	2.30258509299405	NA	1.75493825865991	1.50004233629187	0.254895922368034	1.48369349531021	1.16776058608981	0.201324117245701	0.171798234051529	0.218277552269118	0.929733476031734	NA	NA	0.167537790658415	0.695822205714247	86.1909209178
a10235	loss_cnaOV83	1059	AZD8055	MTORC1/2	5	28	0.693147180559945	NA	0.444384011991237	0.251970514027992	0.192413497963246	1.34163519526043	1.11392928853312	0.167921158195486	0.143417151430569	0.172734032531477	0.929777619844056	NA	NA	0.149155786272251	0.774295365653094	86.1909209178
a10236	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	345	KIN001-270	CDK9	7	25	2.99573227355399	NA	5.2065983280511	5.18637563933208	0.0202226887190182	0.551100732935946	0.824631767103683	0.0260045081775801	0.036695085871658	0.0245232957615075	0.929909067715355	NA	NA	0.336561319807195	0.940370298512944	86.1909209178
a10237	PIK3R1_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	1.6094379124341	NA	1.47722912637716	1.31348787586205	0.163741250515114	0.989024782491823	1.41259425461448	0.120218984328544	0.165558288744365	0.115915274311945	0.92995039281775	NA	NA	0.583261342213768	0.762191356582134	86.1909209178
a10238	gain_cnaOV94	219	AT-7519	CDK9	7	25	2.32630161961136	NA	1.56432757134195	1.47905414378233	0.0852734275596134	1.34604819451024	1.79945516267494	0.0496245618155017	0.0633509467992267	0.0473884703150102	0.930125026169551	NA	NA	0.319069444758592	0.893304407512952	86.1909209178
a10239	loss_cnaOV21, loss_cnaOV22	1262	UNC1215	LMBL3	3	30	0	NA	2.81554394120893	2.77689958087259	0.0386443603363444	0.249613079396006	0.51139654199991	0.077494581474002	0.154817048969761	0.0755663309439258	0.930177896533761	NA	NA	0.111757940766155	0.833016585489222	86.1909209178
a10240	KRAS_mut	208	SB-715992	KIF11	7	25	-2.05572501506252	NA	-1.65646681529311	-1.22246008217621	-0.434006733116899	1.87397767434478	1.87922789275385	0.231078468964139	0.231596533437169	0.230949495157236	0.9301937155017	NA	NA	0.0758385690750013	0.600580056258415	86.1909209178
a10241	loss_cnaOV39	1378	Bleomycin (50 uM)	DNA damage	10	22	3.91202300542815	NA	2.19951910722571	1.97025923843634	0.229259868789367	2.73198075681427	1.58808973909093	0.114564994873429	0.0839170877091771	0.14436203644298	0.930302764152406	NA	NA	0.134762438030996	0.809078332941113	86.1926080217399
a10242	loss_cnaOV40	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	2.22475456287327	2.20476570565003	0.0199888572232436	1.58263103551473	1.28422698543422	0.0150835708954439	0.0126301435866525	0.0155648942515291	0.930445819549264	NA	NA	0.689449602826226	0.985090949606056	86.1974452157152
a10243	TP53_mut	1143	HG-5-88-01	EGFR, ADCK4	16	6	2.30258509299405	NA	3.62092350938991	3.62887660011388	-0.00795309072396266	0.884244064534252	1.00651154584873	0.00867917614871913	0.00899422573806216	0.00790163884037348	0.930858159274133	NA	NA	0.0620524180732935	0.986813809421691	86.2272258032047
a10244	loss_cnaOV33_(ZFHX3)	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	4	19	2.30258509299405	NA	1.67284128860095	1.54004399009419	0.132797298506757	2.13024393268537	0.782870027280518	0.122582313342534	0.0623390103213924	0.169628793898342	0.931323873157192	NA	NA	0.458125848564664	0.909531459231448	86.2457755753936
a10245	loss_cnaOV56	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.28053107115497	-4.13678280765928	-0.143748263495691	0.82821947590459	2.44511570100395	0.060741773442631	0.173563007968011	0.0587899637782656	0.931369205382011	NA	NA	0.928521115608891	0.83625749523125	86.2457755753936
a10246	KRAS_mut	185	OSI-906	IGF1R	3	15	0.940007258491471	NA	2.2409855225289	2.2015195137189	0.0394660088099972	1.57629894305726	1.28525860506277	0.0297825435420102	0.0250371346017984	0.0307066676344638	0.931452957029118	NA	NA	0.689451818170343	0.970464426587545	86.2457755753936
a10247	loss_cnaOV16, loss_cnaOV17	238	CAL-101	PI3Kdelta	6	26	2.99573227355399	2.32630161961136	4.4000062613101	4.38427188016729	0.0157343811428099	0.737682210374329	1.03716897587862	0.0158366298816934	0.0213294843247279	0.0151705088647496	0.931469128724599	NA	NA	0.514079862914709	0.966303141825648	86.2457755753936
a10248	loss_cnaOV43_(NF1)	308	XL-880	MET	5	27	1.63315443905142	NA	0.159035984595194	0.270517366655324	-0.11148138206013	0.371209216861021	1.04068985601073	0.113958200228824	0.30031954217847	0.107122579715989	0.931567358453202	NA	NA	0.371223468641394	0.673284587993724	86.2457755753936
a10249	gain_cnaOV51_(MYC)	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.16737339953224	3.83348885322738	0.333884546304866	0.815826558137284	1.60257607457668	0.220327575665506	0.409259226700341	0.208342400464865	0.93160379390769	NA	NA	0.0719930590481384	0.558416444505232	86.2457755753936
a10250	gain_cnaOV72_(ASXL1)	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	2.43099463029005	2.44928887372359	-0.0182942434335391	0.841410446265461	0.866156344859133	0.0212269343293996	0.0217423535858591	0.0211211792676003	0.931883916513988	NA	NA	0.625784775573577	0.970900903931927	86.2632919416691
a10251	loss_cnaOV1	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	0.817858000195714	0.683558488237938	0.134299511957776	1.42076734727968	2.38105012548236	0.0576546142957809	0.0945260406039859	0.0564034795069965	0.932191393825751	NA	NA	0.946174069005818	0.893737918232496	86.2765450544969
a10252	gain_cnaOV51_(MYC)	190	Bleomycin	DNA damage	5	14	4.15888308335967	NA	1.49217243474606	1.72906038750506	-0.236887952758997	2.03449588662986	2.43938173611319	0.100786329048589	0.116435700025623	0.0971098328941515	0.932208946004743	NA	NA	0.617318979883546	0.837392821291164	86.2765450544969
a10253	TP53_mut	344	THZ-2-49	CDK9	22	10	2.99573227355399	NA	2.55060955076625	2.66781134191005	-0.117201791143797	2.46192206390801	2.07663020156337	0.0498101859176666	0.0476058088361062	0.0564384506473818	0.932373382259434	NA	NA	0.388884851271482	0.890479373556261	86.2783609780156
a10254	loss_cnaOV34	1175	AG-014699	PARP1, PARP2	5	28	1.6094379124341	NA	3.94433453780805	3.89344782435254	0.0508867134555069	1.63772155564874	0.974661515001576	0.0469751657173651	0.0310716515148691	0.0522096262879781	0.932486210372831	NA	NA	0.319272888031487	0.949156818564779	86.2783609780156
a10255	ARID1A_mut	1239	YK 4-279	RNA helicase A	9	15	2.30258509299405	NA	1.35058592550078	1.70086308679305	-0.350277161292269	0.842891961292628	1.15537595030428	0.332793927852298	0.415565905688668	0.303171587741652	0.93250193149018	NA	NA	0.291040179079965	0.402344080429778	86.2783609780156
a10256	gain_cnaOV49	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.22305238323502	2.32337513992776	-0.100322756692749	0.992487042962393	1.48342008623809	0.0689100542888693	0.101082182789312	0.067629363808309	0.932972461938622	NA	NA	0.822033619882077	0.884581576238487	86.2783609780156
a10257	loss_cnaOV57_(ZNRF3)	310	YM201636	FYV1	4	28	1.63315443905142	NA	2.29519003604409	2.36573464808009	-0.070544612036004	1.25227225264511	0.821860270783789	0.0806697123902875	0.0563332868607417	0.0858352867802301	0.933035703962168	NA	NA	0.652579440641089	0.919100185350645	86.2783609780156
a10258	loss_cnaOV35	1038	NU-7441	PRKDC (DNAPK)	5	28	0.693147180559945	NA	2.56721311455432	2.53165736170166	0.0355557528526687	0.91307723738737	1.06157618791772	0.0340701881381036	0.0389405752293267	0.0334933594567633	0.93312711833935	NA	NA	0.397935648629762	0.940203990918403	86.2783609780156
a10259	loss_cnaOV70	345	KIN001-270	CDK9	3	29	2.99573227355399	NA	5.27748133377615	5.18183225097694	0.0956490827992074	0.523451481664884	0.792195271735359	0.123072681033853	0.182727695210618	0.120739275039702	0.933240736156462	NA	NA	0.336567322527214	0.794215363574403	86.2783609780156
a10260	loss_cnaOV83	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-0.920728359152426	-1.23143798935797	0.310709630205543	1.28368980295075	1.34780989897824	0.232074120238262	0.24204416790671	0.23052926858683	0.933336717570632	NA	NA	0.0511693716652324	0.682811755533294	86.2783609780156
a10261	loss_cnaOV87, loss_cnaOV88	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	1.82842764980005	1.53806759766034	0.29036005213971	1.64918463941323	1.63111496566678	0.177881184099149	0.176062792000669	0.178013235272483	0.933344704116168	NA	NA	0.0805987634999403	0.794390212785725	86.2783609780156
a10262	loss_cnaOV33_(ZFHX3)	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.673276760763032	-0.836495570400805	0.163218809637773	0.923212116324565	0.797563702356995	0.201141025979502	0.176794483902106	0.204646737502498	0.933439361578898	NA	NA	0.0805930129489061	0.755404288868915	86.2783609780156
a10263	loss_cnaOV58	1194	SB-505124	TGFR1 (ALK5)	5	27	2.30258509299405	NA	4.616036716495	4.58332617010629	0.0327105463887021	1.53375592367198	0.827169910006074	0.0343535193407582	0.0213270872397933	0.0395451357611181	0.933572186949503	NA	NA	0.943493246946635	0.964963688765213	86.2783609780156
a10264	loss_cnaOV36	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.911949428985574	-1.21721934737272	0.305269918387145	1.56282143257448	1.3145602422476	0.227781582853955	0.195332564568343	0.232222083535102	0.933604188292963	NA	NA	0.0511696757820504	0.773176410360567	86.2783609780156
a10265	loss_cnaOV58	1024	CEP-701	FLT3, JAK2, NTRK1, RET	5	26	0.693147180559945	NA	0.104263368732783	-0.20816984465002	0.312433213382802	2.37900235835425	1.45958241333805	0.193125961210952	0.131329509735727	0.21405657572173	0.933703557709402	NA	NA	0.102673200157268	0.789058869192582	86.2783609780156
a10266	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1022	AZD7762	CHEK1, CHEK2	4	27	0.693147180559945	NA	-0.733857031621775	-0.827520715458769	0.0936636838369941	0.968300658017032	0.79288168989946	0.115237807825687	0.0967299599163822	0.118130718655984	0.933706528026384	NA	NA	0.0805933049726721	0.863475332399256	86.2783609780156
a10267	loss_cnaOV54	155	AP-24534	ABL	6	13	-0.669430653942629	NA	0.768018671825303	0.798027226376354	-0.0300085545510512	1.02814929932268	1.36511533352526	0.0235308816908822	0.0291869620208077	0.0219824316774448	0.933855160904092	NA	NA	0.588398839343762	0.958476435535018	86.2783609780156
a10268	loss_cnaOV54	225	Genentech Cpd 10	AURKA, AURKB	10	22	2.32630161961136	NA	3.00274834651749	2.77206349020572	0.230684856311773	1.73662351864522	1.91741315855952	0.123690462836969	0.132835271338335	0.120310458537313	0.93394311794856	NA	NA	0.349281739592594	0.739804166717449	86.2783609780156
a10269	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.32484087004328	2.40063948794201	-0.0757986178987355	1.65088522565664	0.878913399266869	0.0797798726751763	0.0459139234640533	0.08624128152098	0.934163410616277	NA	NA	0.736384362677837	0.94430154733973	86.2783609780156
a10270	KRAS_mut	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	3	16	2.77258872223978	NA	5.03318198362063	5.03148446626161	0.00169751735902324	0.690909072558948	1.25416312729121	0.00141262024723711	0.00245693308489361	0.0013535060328951	0.934163633111541	NA	NA	0.802968031207724	0.997460370771469	86.2783609780156
a10271	gain_cnaOV18_(CCNE1)	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-4.15164698598718	-4.0499292804592	-0.10171770552798	0.816212112191242	1.57752323375854	0.0661719655468719	0.124621656562905	0.0644793707954663	0.934202783419537	NA	NA	0.864950466597996	0.864401814022244	86.2783609780156
a10272	gain_cnaOV19	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-4.15164698598718	-4.0499292804592	-0.10171770552798	0.816212112191242	1.57752323375854	0.0661719655468719	0.124621656562905	0.0644793707954663	0.934202783419537	NA	NA	0.864950466597996	0.864401814022244	86.2783609780156
a10273	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	271	VNLG/124	HDAC, RAR 	5	26	1.63315443905142	NA	4.39623119321937	4.31649386144942	0.0797373317699472	0.521092427823351	0.602113243572946	0.1347829596618	0.153019555672718	0.132429127944081	0.934300988841092	NA	NA	0.257020606526693	0.77010995796561	86.2783609780156
a10274	loss_cnaOV82	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	2.65064534502881	2.52568452217772	0.124960822851087	1.27084494657694	1.02545214378378	0.119805862584536	0.0983289292589725	0.121859243855104	0.934360450398418	NA	NA	0.397937686157647	0.882483393572754	86.2783609780156
a10275	gain_cnaOV95_(MECOM)	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.15946018319014	3.07602536688369	0.0834348163064522	0.571325137908848	1.06221588156435	0.0860737255397929	0.146037362563528	0.0785478900800993	0.934421925013298	NA	NA	0.674396965938887	0.830321749568156	86.2783609780156
a10276	loss_cnaOV55	208	SB-715992	KIF11	7	25	-2.05572501506252	NA	-1.04470270336934	-1.39375403351487	0.349051330145536	1.35666915454538	1.99109679563957	0.185526985395659	0.257285520921645	0.175306057902331	0.934511076237137	NA	NA	0.0758430550608353	0.599196181487225	86.2783609780156
a10277	loss_cnaOV70	1019	Bosutinib	SRC, ABL, TEC	3	28	0.693147180559945	NA	1.91001901892569	1.70351084809568	0.206508170830009	1.86351656220512	1.5910223890508	0.128162837721471	0.110816386083333	0.12979589240929	0.934616765569106	NA	NA	0.0424503044442363	0.86824796463267	86.2783609780156
a10278	loss_cnaOV36	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	1.82699253015641	1.53821605831313	0.288776471843274	1.64892623535893	1.63116092263925	0.176908287608788	0.175130012277605	0.177037389650083	0.934660840807509	NA	NA	0.0806001452487314	0.79544001585192	86.2783609780156
a10279	gain_cnaOV18_(CCNE1)	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	2.58256637455852	2.35105120059412	0.231515173964396	1.81578751780672	1.24989740168209	0.176011046479286	0.127501247637192	0.185227342382524	0.934890461181735	NA	NA	0.112095576604172	0.81903282008252	86.2783609780156
a10280	gain_cnaOV96	193	GW-2580	CSF1R (cFMS)	5	27	2.99573227355399	NA	5.7998884071148	5.71287916063322	0.087009246481581	0.807675654900279	0.571750072795326	0.142986220949303	0.107727954846335	0.152180560390988	0.934943984472241	NA	NA	0.195042441830174	0.827309334460047	86.2783609780156
a10281	loss_cnaOV16, loss_cnaOV17	253	XMD14-99	EPHB3, CAMK1	6	26	2.32630161961136	NA	4.9587291783885	4.8372949697616	0.121434208626903	0.577038258490205	0.63249040325711	0.194733771131661	0.210443946896399	0.191993756745649	0.934956250356004	NA	NA	0.0509955465286859	0.660385631528373	86.2783609780156
a10282	PIK3CA_mut	164	JQ12	HDAC	5	14	1.63315443905142	NA	1.95819401242057	1.73521414498153	0.222979867439032	1.52627323339839	2.41960114782417	0.0994705928248305	0.146094331316122	0.0921556297158923	0.934997635199142	NA	NA	0.66396106340067	0.816698493156534	86.2783609780156
a10283	loss_cnaOV35	196	Phenformin	AAPK1 (AMPK) agonist	5	26	8.29404964010203	NA	8.68745196132867	8.77098103429786	-0.0835290729691867	2.12681882585216	1.64946545493272	0.0484735944172782	0.0392741835617892	0.0506400862894056	0.935139183734203	NA	NA	0.922295010091688	0.936983918323136	86.2783609780156
a10284	gain_cnaOV94	229	LY317615	PRKCB (PKCbeta)	7	25	2.99573227355399	2.32630161961136	2.9079462640889	2.70451906384827	0.203427200240625	1.96786385708227	1.61515805121436	0.120257786261358	0.103374631079533	0.125948788781183	0.935194556345054	NA	NA	0.324270836999208	0.807944631048433	86.2783609780156
a10285	PIK3CA_mut	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.03077207705721	1.65964644800589	-0.628874370948677	1.36561096500549	1.24007541896266	0.502065899721596	0.460507704656683	0.507125906482962	0.935233120054658	NA	NA	0.167549954663739	0.515769098794139	86.2783609780156
a10286	gain_cnaOV26	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	3.93348557135869	3.89792516856118	0.0355604027975076	1.26081144036858	1.07006010600497	0.0328235541778972	0.0282043782749244	0.0332321545284694	0.93532023398236	NA	NA	0.319277656049275	0.966155546417647	86.2783609780156
a10287	loss_cnaOV85	1023	GW 441756	NTRK1	7	24	0.693147180559945	NA	2.31250422673148	2.29437492336431	0.018129303367171	1.33821114866723	1.24815271734407	0.0143053346721894	0.0135474161795966	0.0145249079822124	0.935505689070821	NA	NA	0.84550403997053	0.97514132765107	86.2821722859604
a10288	loss_cnaOV35	1199	Tamoxifen	ER	5	27	1.6094379124341	NA	4.04303273443786	3.96814393298585	0.0748888014520097	0.967330219289015	0.731689556381835	0.0976003026407594	0.0774180315663588	0.102350512999435	0.935580230035633	NA	NA	0.528134745227568	0.875845243029425	86.2821722859604
a10289	gain_cnaOV96	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.39860227451553	4.31909582465628	0.0795064498592533	0.740547704999303	0.572076708278174	0.134361980952449	0.107361685577472	0.138978652178569	0.935634357542543	NA	NA	0.257022918702662	0.84818457238557	86.2821722859604
a10290	TP53_mut	134	Etoposide	TOP2	12	7	2.77258872223978	NA	2.23109550100852	2.37282272322598	-0.141727222217455	2.13916940530079	1.15286668298223	0.0765247767847657	0.0662533887527842	0.122934615345841	0.936184324939878	NA	NA	0.414268584356428	0.853474197048339	86.3187165354075
a10291	loss_cnaOV20	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	3.870275058305	4.06276672151461	-0.192491663209606	1.32201113706879	1.53487196860792	0.127627756976672	0.145605175185139	0.12541219537952	0.936231276907751	NA	NA	0.332703210291044	0.780375519554722	86.3187165354075
a10292	KRAS_mut	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-4.39948889238223	-4.70183612979765	0.30234723741542	2.93892880687958	1.94229268128994	0.145050619208046	0.102876679662219	0.15566512726322	0.936303561105093	NA	NA	0.355080243884963	0.877681932498948	86.3187165354075
a10293	loss_cnaOV59	224	AS605240	PI3Kgamma	4	28	2.99573227355399	2.32630161961136	3.38339532289823	3.37391617848296	0.0094791444152631	2.27944229978526	1.60258615463158	0.00563373153196619	0.00415853668072936	0.00591490472313624	0.936470985794265	NA	NA	0.631885850909771	0.994030954536557	86.3191559362403
a10294	SMARCA4_mut	1203	QL-XII-61	BTK	3	20	2.30258509299405	NA	3.60980118955693	3.93381891203892	-0.324017722481991	1.75251733296147	1.48991470782221	0.21360739109156	0.184887028725961	0.217474007593095	0.936524760517812	NA	NA	0.0719999431595273	0.784908327389851	86.3191559362403
a10295	loss_cnaOV82	1052	RO-3306	CDK1	3	30	1.6094379124341	NA	3.54004429492427	3.47596379680933	0.0640804981149325	1.45993263663227	0.861775207014009	0.0702422112356408	0.043892777315227	0.0743587162793497	0.936774383241032	NA	NA	0.795421138013092	0.946827021253293	86.3191559362403
a10296	MLL2_mut	1248	FK866	NAMPT	3	29	0	NA	-4.04544038004769	-1.46659058053277	-2.57884979951492	2.27303761377611	2.69603332991769	0.965890523880558	1.13453899041766	0.956534836160077	0.936826437188094	NA	NA	0.0458263166374869	0.17685044209399	86.3191559362403
a10297	gain_cnaOV19	204	Tipifarnib	Farnesyl-transferase (FNTA)	3	16	2.77258872223978	NA	1.80419646243585	1.87133531046854	-0.0671388480326862	1.08483726910932	1.75255740569998	0.0397796369557218	0.0618884047814921	0.0383090721104628	0.936897159598659	NA	NA	0.351214216797703	0.933948277902358	86.3191559362403
a10298	loss_cnaOV87, loss_cnaOV88	329	QL-XI-92	DDR1	3	29	2.32630161961136	NA	4.5795113045803	4.52893268031542	0.0505786242648743	1.87402092748028	0.935841090310525	0.0493234724840134	0.0269893593626406	0.0540461674407688	0.936901499594949	NA	NA	0.194044463537502	0.967195037438187	86.3191559362403
a10299	gain_cnaOV96	211	TL-2-105	CRAF	5	27	2.32630161961136	1.63315443905142	4.47694519665019	4.39659547312737	0.0803497235228159	0.610158387999181	0.640460376437388	0.126236113072804	0.131686665467793	0.12545619757114	0.93694514797422	NA	NA	0.274066933936451	0.797774948696297	86.3191559362403
a10300	loss_cnaOV33_(ZFHX3)	1032	Afatinib	ERBB2, EGFR	4	27	-0.693147180559945	NA	0.322341785229567	0.362244577115299	-0.0399027918857326	1.94011491526885	1.65841306107355	0.0236148378005109	0.0205672311323905	0.0240608282835774	0.937387163162916	NA	NA	0.838244389734386	0.970858186016387	86.3288906828999
a10301	TP53_mut	255	CP724714	ERBB2	22	10	2.32630161961136	NA	4.42585173508647	4.39134874806514	0.0345029870213285	1.01231043527223	0.817808195797877	0.0360113327343966	0.0340834054645007	0.0421895833260345	0.937414626009067	NA	NA	0.787749030465443	0.91936624294105	86.3288906828999
a10302	gain_cnaOV94	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	5.01739412161355	4.71254399624872	0.304850125364836	1.56616736589002	1.5896836372441	0.19209993182661	0.19464722098305	0.19176779468733	0.937628439035409	NA	NA	0.125572937529648	0.778882982640065	86.3288906828999
a10303	TP53_mut	1025	SB 216763	GSK3A, GSK3B	16	7	2.30258509299405	NA	4.92850078457654	5.03185388786584	-0.103353103289296	0.935434883442483	0.493785111407183	0.124001680243406	0.110486689259383	0.209307856599325	0.937644589114675	NA	NA	0.458116329662438	0.733386507473416	86.3288906828999
a10304	PIK3CA_mut	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-3.33497908713167	-3.49990528015668	0.164926193025011	1.36451614904874	1.90297934196181	0.0920908767448549	0.12086789382448	0.0866673585930717	0.937681090471036	NA	NA	0.684746265264833	0.839695817856647	86.3288906828999
a10305	loss_cnaOV54	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	10	21	2.32630161961136	NA	2.20257349716602	2.33727980922961	-0.134706312063584	1.17906105807425	1.51812135018405	0.0947583974996569	0.114248800892126	0.0887322426808983	0.937735993338651	NA	NA	0.532559118761587	0.789559608974611	86.3288906828999
a10306	loss_cnaOV83	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.36808382524267	3.22952605465276	0.138557770589905	1.65751140783838	0.942899053473858	0.13304009590989	0.0835938563889607	0.146948679266806	0.937762095367064	NA	NA	0.569380450101745	0.899612151413376	86.3288906828999
a10307	TP53_mut	271	VNLG/124	HDAC, RAR 	21	10	1.63315443905142	NA	4.33004448898867	4.32790620950196	0.00213827948670797	0.676958825312556	0.335132641399711	0.00360968023088785	0.00315865516003978	0.00638039755774687	0.937800562347098	NA	NA	0.257026573164843	0.990696972116893	86.3288906828999
a10308	loss_cnaOV52, loss_cnaOV53	238	CAL-101	PI3Kdelta	8	24	2.99573227355399	2.32630161961136	4.40795724334039	4.3803103543953	0.0276468889450978	1.09673285711929	0.959862363685143	0.0278281380149075	0.0252084076497133	0.0288029721667123	0.93795258477435	NA	NA	0.514089649664478	0.950419796114822	86.3288906828999
a10309	loss_cnaOV34	1039	SL 0101-1	RSK, AURKB, PIM3	5	28	2.30258509299405	NA	4.96016312844457	4.93364517770599	0.0265179507385849	1.16571855629316	0.76225449314208	0.0321246401461962	0.0227481587175799	0.0347888414921315	0.937960659496067	NA	NA	0.946301400125682	0.962939910689934	86.3288906828999
a10310	gain_cnaOV50	265	Tubastatin A	HDAC6	4	27	2.99573227355399	NA	4.64189503976477	4.77322650506009	-0.131331465295316	0.816402436223995	1.27729287964995	0.106117880075303	0.160866086954306	0.102820165513887	0.938055849390773	NA	NA	0.427825250972081	0.792924906536286	86.3292776924297
a10311	gain_cnaOV49	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.77995239779323	4.79663466063987	-0.0166822628466434	0.429715536329739	0.683616935198201	0.0249103614342537	0.0388216423104665	0.0244029396986877	0.938404754271282	NA	NA	0.763527301160622	0.955844166464602	86.3430539062748
a10312	loss_cnaOV85	185	OSI-906	IGF1R	5	13	0.940007258491471	NA	2.12241402742783	2.24105224124854	-0.118638213820716	1.27005210982596	1.34154234149089	0.0896037553511437	0.093412083569526	0.0884341926091351	0.938675827634645	NA	NA	0.689466750284557	0.865804817033557	86.3430539062748
a10313	loss_cnaOV70	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.7089948184943	2.87977827810237	-0.170783459608071	0.529460237774222	0.824614197029105	0.211287922138852	0.322561445456265	0.207107105629959	0.93870609179793	NA	NA	0.0201873200490704	0.650563679921915	86.3430539062748
a10314	loss_cnaOV70	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.33981545734968	4.30469810403773	0.0351173533119491	1.49213854888235	1.30791308041058	0.0265924842899667	0.0235349145950641	0.0268499136815155	0.938723660329493	NA	NA	0.373934830238237	0.971791984689867	86.3430539062748
a10315	loss_cnaOV33_(ZFHX3)	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	-1.38629436111989	0.693147180559945	-2.22094107228652	-2.11014616366818	-0.110794908618347	0.879168260315494	1.34076948959887	0.0850134353069746	0.126022416435492	0.0826353146292836	0.938792405380748	NA	NA	0.609695875824733	0.834794638089649	86.3430539062748
a10316	loss_cnaOV84	1031	Elesclomol	HSP70	6	25	-1.6094379124341	NA	-4.12423488268985	-4.0443020605872	-0.0799328221026494	2.08976008688118	1.39471750652973	0.0520010069290256	0.0382497601540201	0.0573111197991157	0.938875433650391	NA	NA	0.864952740086371	0.931886359749067	86.3430539062748
a10317	gain_cnaOV51_(MYC)	226	GSK1070916	AURKB	8	24	0.940007258491471	2.32630161961136	2.32567250108523	2.31006900828868	0.0156034927965414	0.79424051434433	1.60427718831618	0.0107156006247113	0.0196458031474541	0.0097261825513573	0.938976936217653	NA	NA	0.822037339682736	0.971433926493831	86.3430539062748
a10318	PIK3CA_mut	1218	JQ1	BRD2, BRD3, BRD4	6	25	0	NA	2.39617810350325	2.26945927190813	0.126718831595125	0.539458310027432	0.965899670822549	0.139743254840833	0.234900138230665	0.131192540408687	0.938988564528862	NA	NA	0.596765703414261	0.671954975292797	86.3430539062748
a10319	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.37760742477659	3.31977303763972	0.0578343871368729	1.97899352991044	1.17012181031696	0.0466194097326228	0.0292241415966075	0.0494259543125746	0.939053686601516	NA	NA	0.99365130312111	0.964583075196715	86.3430539062748
a10320	gain_cnaOV72_(ASXL1)	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	4.83024383741593	4.86558611470567	-0.0353422772897352	0.370847255363019	0.655816469309766	0.056514288618251	0.0953014395512755	0.0538904997718832	0.939115537712559	NA	NA	0.050998693279149	0.86890230691152	86.3430539062748
a10321	loss_cnaOV70	1005	Cisplatin	DNA crosslinker	3	28	1.79175946922805	2.30258509299405	3.23242349779101	3.00119103108158	0.231232466709429	0.858147482613271	1.22210707773932	0.192604800601243	0.269455392452203	0.189208025156983	0.939329179770837	NA	NA	0.0905254136204507	0.701198058376715	86.3457789822807
a10322	loss_cnaOV43_(NF1)	262	VX-11e	ERK	5	27	1.63315443905142	NA	2.75837696448074	2.87796288781928	-0.119585923338542	1.27267883747198	1.10487541413177	0.105950934951377	0.0939639442548482	0.108234758244227	0.939345553196264	NA	NA	0.393692021394468	0.851458261225267	86.3457789822807
a10323	loss_cnaOV84	157	JNK-9L	JNK	5	14	1.63315443905142	NA	-0.166366943433475	0.0166673831940049	-0.18303432662748	1.35281439700687	0.888804804543973	0.179938041469943	0.135298919816678	0.205933097674231	0.939502021938074	NA	NA	0.195320104449726	0.788930602719091	86.3457789822807
a10324	PTEN_mut	1262	UNC1215	LMBL3	4	29	0	NA	2.53548894719478	2.81419529175949	-0.27870634456471	0.199333101768462	0.511325457107869	0.568910564141647	1.39819398831432	0.545066436044694	0.939509186927979	NA	NA	0.111769106525288	0.0703410740781556	86.3457789822807
a10325	loss_cnaOV38	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-2.32366010072438	-2.60478668965216	0.281126588927778	3.4282967516074	1.56795498161923	0.138860028807987	0.0820018246075017	0.179295064095181	0.939835388585657	NA	NA	0.350452477710521	0.88235466734307	86.350780419882
a10326	gain_cnaOV19	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.79216394728231	2.74455546906835	0.0476084782139647	2.03502877421624	1.66671240204023	0.0281081537175044	0.0233944987988194	0.0285643030889354	0.939853748364789	NA	NA	0.324278499255731	0.971901988731599	86.350780419882
a10327	loss_cnaOV56	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.4301108852371	4.43129393201254	-0.00118304677544234	1.45965137304943	0.663902872510246	0.00159028131311389	0.000810499546183266	0.00178195760920448	0.940082813696782	NA	NA	0.526922805282079	0.999013146679086	86.350780419882
a10328	loss_cnaOV38	140	Vinorelbine	Microtubules	4	15	-2.74887219562247	NA	-3.57762563719632	-3.42420445393777	-0.153421183258549	2.75586432421861	1.50633021077414	0.0856464268467531	0.0556708042229363	0.101850963461525	0.940096785366561	NA	NA	0.684750719753611	0.920533104023395	86.350780419882
a10329	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.50897765558937	3.48753584991614	0.0214418056732297	0.737340481554042	1.14681631635354	0.0190868906553552	0.0290799246883045	0.0186968090421026	0.940178540947366	NA	NA	0.728486455288684	0.966889263742813	86.350780419882
a10330	loss_cnaOV1	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.93777947762466	3.91793732207022	0.0198421555544352	1.10689018476819	1.24044255977227	0.0161096071494156	0.0179260380365471	0.0159960293188247	0.940214671897914	NA	NA	0.700598597461439	0.978856338243582	86.350780419882
a10331	KRAS_mut	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-1.89406027052044	-2.22457788098579	0.330517610465353	3.47433466276918	2.57040481926715	0.122752793925221	0.0951311956234859	0.128585819629605	0.940248593894679	NA	NA	0.422041324682989	0.88741667608625	86.350780419882
a10332	SMAD4_mut	203	BMS-345541	IKBKB	3	29	2.77258872223978	NA	3.43569458260483	3.25969052031493	0.176004062289908	1.36158633742837	1.02250319828757	0.16785858421451	0.129263975006041	0.172130573855093	0.940332157950324	NA	NA	0.0938710124588976	0.845960915394389	86.350780419882
a10333	TP53_mut	204	Tipifarnib	Farnesyl-transferase (FNTA)	12	7	2.77258872223978	NA	1.81172087074526	1.94475770083729	-0.133036830092037	1.60574000326905	1.82557459136078	0.0788785345359464	0.0828507914240126	0.0728739492330859	0.94047158431835	NA	NA	0.351224658216981	0.875652545785691	86.350780419882
a10334	gain_cnaOV94	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	7	25	1.63315443905142	NA	2.75915727847514	2.89305814284503	-0.133900864369887	0.419676668185721	0.878559698299008	0.165737244749031	0.319057204082242	0.152409522800937	0.940544714591437	NA	NA	0.0201880186237319	0.577453517975724	86.350780419882
a10335	loss_cnaOV34	235	QL-XII-47	BTK, BMX	5	27	2.32630161961136	NA	1.70786563887235	1.53888574396994	0.168979894902412	1.18386719034948	1.69203126288695	0.103450585097168	0.142735516517296	0.0998680689942444	0.940564691275378	NA	NA	0.080606001731387	0.793123928145321	86.350780419882
a10336	gain_cnaOV72_(ASXL1)	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.83897049418544	1.71972023357018	0.119250260615261	1.8712817437178	1.68967162744831	0.0695666701669293	0.0637265131322972	0.0705759975358933	0.940877421121893	NA	NA	0.232015048180449	0.899056233758188	86.3516390383016
a10337	loss_cnaOV84	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-0.931768722692699	-1.24563286783042	0.313864145137724	1.11198205056795	1.3854227701215	0.234637546906712	0.282256485145076	0.226547557833339	0.940962868134527	NA	NA	0.051177559575404	0.612378880763487	86.3516390383016
a10338	loss_cnaOV85	1166	QL-VIII-58	MTOR, ATR	5	18	2.30258509299405	NA	-0.931768722692699	-1.24563286783042	0.313864145137724	1.11198205056795	1.3854227701215	0.234637546906712	0.282256485145076	0.226547557833339	0.940962868134527	NA	NA	0.051177559575404	0.612378880763487	86.3516390383016
a10339	loss_cnaOV54	255	CP724714	ERBB2	10	22	2.32630161961136	NA	4.37897044306588	4.43147823735886	-0.0525077942929784	1.29036222974652	0.772855877499884	0.0548139646902135	0.0406922901821863	0.0679399559757973	0.940987433945909	NA	NA	0.787751516902401	0.906990614666301	86.3516390383016
a10340	loss_cnaOV52, loss_cnaOV53	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-2.44909647445681	-2.58006845538542	0.130971980928607	1.33629870470733	2.19653601460286	0.0646061213424274	0.0980110064218697	0.059626603004862	0.941107200963803	NA	NA	0.35045608418725	0.878359944429411	86.3516390383016
a10341	gain_cnaOV95_(MECOM)	328	SNX-2112	HSP90	9	23	0.940007258491471	NA	0.747142474926362	0.676195125441308	0.0709473494850541	2.74943209984193	2.15661574174182	0.0304560680824023	0.0258043650138271	0.0328975385423795	0.941201619785886	NA	NA	0.946175765283553	0.94573225613525	86.3516390383016
a10342	gain_cnaOV48_(SOX17)	281	CH5424802	ALK	3	29	1.63315443905142	NA	3.90005302386662	3.93045592768084	-0.0304029038142195	0.460113431511797	0.751399811582775	0.0413319842600153	0.0660769752239672	0.040461686768563	0.941268454116209	NA	NA	0.95606372971396	0.925247041264374	86.3516390383016
a10343	loss_cnaOV33_(ZFHX3)	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.51498374824961	4.51628975619105	-0.00130600794144087	0.667698419519111	0.599297867163607	0.0021619108018149	0.0019559847728582	0.00217923008406825	0.941395079656124	NA	NA	0.61724705775589	0.99765904469251	86.3516390383016
a10344	loss_cnaOV42	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	28	2.99573227355399	NA	3.97108460084015	4.04149065603781	-0.0704060551976688	1.21544714449005	1.53899338714852	0.0466338721496722	0.0579260525781303	0.0457481206778404	0.941504249150267	NA	NA	0.332711692216104	0.921261702342396	86.3516390383016
a10345	gain_cnaOV94	1230	IOX2	EGLN1	7	25	-2.30258509299405	NA	-0.132086037784839	-0.0441265154162392	-0.0879595223685994	0.865246444495015	0.996466238057495	0.0905267701137322	0.101658345929333	0.0882714526686496	0.941505154689078	NA	NA	0.551417865980866	0.822593739335353	86.3516390383016
a10346	SMARCA4_mut	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.76971571456359	4.85887471119272	-0.0891589966291289	0.6440303814579	0.925756210593651	0.0980702494909992	0.138439115911424	0.0963093691501725	0.941575138438435	NA	NA	0.667382605072108	0.842270212798447	86.3516390383016
a10347	loss_cnaOV81_(RB1)	253	XMD14-99	EPHB3, CAMK1	4	28	2.32630161961136	NA	4.96121577708396	4.84561361342131	0.11560216366265	0.394008366602161	0.644789810028618	0.185182190523424	0.293400276394069	0.179286585899239	0.942007733434907	NA	NA	0.0510007579993435	0.636595201259651	86.3664859657851
a10348	loss_cnaOV55	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.6094379124341	NA	1.10772325278775	1.18712208369336	-0.0793988309056137	2.05659804502964	1.3000222022461	0.0527744469795159	0.0386068785281129	0.0610749806952782	0.942013694867245	NA	NA	0.814180653985847	0.920394155775724	86.3664859657851
a10349	gain_cnaOV4_(KRAS)	304	SB52334	ALK5	8	24	2.99573227355399	NA	4.3906649706831	4.35863231159652	0.0320326590865845	0.906803606185259	1.11631788533161	0.029906231797132	0.0353248033731796	0.0286949259771726	0.942217631882584	NA	NA	0.354782516557515	0.936189994148535	86.3664859657851
a10350	gain_cnaOV48_(SOX17)	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.24150296157028	4.14194392308674	0.0995590384835419	0.545662211612115	1.06338418446017	0.0959322159080021	0.182455439216512	0.0936247124402019	0.942266491396931	NA	NA	0.532150360629531	0.801976711253772	86.3664859657851
a10351	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1001	AICAR	AAPK1 (AMPK) agonist	8	23	7.60090245954208	NA	8.73578883371481	8.75437942363535	-0.0185905899205476	1.10904761148888	1.28600368122795	0.014925080097005	0.0167626616999698	0.0144560938603195	0.942418323972516	NA	NA	0.532565447198599	0.969331055978677	86.3664859657851
a10352	gain_cnaOV95_(MECOM)	286	KIN001-236	TIE2	9	23	2.32630161961136	NA	4.81052755702901	4.78902236255109	0.0215051944779256	0.715506038594809	0.652156699880377	0.0321147479516147	0.0300559231060579	0.0329755018722805	0.942717695262201	NA	NA	0.763530549127667	0.938712172659542	86.3664859657851
a10353	loss_cnaOV52, loss_cnaOV53	235	QL-XII-47	BTK, BMX	8	24	2.32630161961136	NA	1.79002443110251	1.49037699303042	0.299647438072098	1.38184567591467	1.69729490637149	0.183927288061298	0.21684580506702	0.176544121441271	0.942727406262534	NA	NA	0.0806080074120389	0.624278517771801	86.3664859657851
a10354	BRCA1_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-1.81367569682213	-2.01409616096673	0.200420464144603	1.19850777040787	2.11962700979421	0.0978296728019556	0.167225001867445	0.0945545906041559	0.942796153764462	NA	NA	0.281162744325635	0.789174664383029	86.3664859657851
a10355	gain_cnaOV94	201	Epothilone B	Microtubules	3	16	-3.44201937618241	NA	-4.73106111962651	-4.63966633718935	-0.0913947824371615	1.60041516242609	2.14397292430778	0.0437843551459339	0.0571069211182771	0.0426287017904715	0.942831323884048	NA	NA	0.355099023281066	0.936458463197147	86.3664859657851
a10356	gain_cnaOV18_(CCNE1)	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.97509382962343	4.90407005536874	0.0710237742546873	0.894989153018765	0.865047954229671	0.0819052036197471	0.0793571341229408	0.0821038578351812	0.942937136068931	NA	NA	0.15681397864177	0.905849159956779	86.3664859657851
a10357	gain_cnaOV19	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.97509382962343	4.90407005536874	0.0710237742546873	0.894989153018765	0.865047954229671	0.0819052036197471	0.0793571341229408	0.0821038578351812	0.942937136068931	NA	NA	0.15681397864177	0.905849159956779	86.3664859657851
a10358	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1061	SB590885	BRAF	5	28	1.6094379124341	NA	3.83478965886315	3.94410235379069	-0.10931269492754	2.02886268138954	1.14483788417438	0.0845211495865847	0.0538788040857815	0.0954831216180216	0.942963684541362	NA	NA	0.575441825769938	0.91179365070877	86.3664859657851
a10359	loss_cnaOV70	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.40870514138269	4.28789340087811	0.120811740504575	0.562558673237082	0.822487840542314	0.149657806821214	0.214754027005572	0.146885746572152	0.942995544849724	NA	NA	0.228034447238935	0.75926135276155	86.3664859657851
a10360	gain_cnaOV51_(MYC)	1248	FK866	NAMPT	8	24	0	NA	-1.23346094479411	-1.86665668405169	0.633195739257579	2.56654905122639	2.8239595695933	0.228917733363891	0.24671094400281	0.22422266454359	0.943043869793343	NA	NA	0.0458304998394681	0.565847483663999	86.3664859657851
a10361	loss_cnaOV84	1239	YK 4-279	RNA helicase A	4	20	2.30258509299405	NA	1.72413650905345	1.53858367975945	0.185552829294007	0.87018433168699	1.09246150950774	0.174246573480298	0.213233935083942	0.169848390702219	0.943175130790733	NA	NA	0.291064144678834	0.724918078314618	86.3664859657851
a10362	loss_cnaOV56	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.71132009631478	2.87953773212094	-0.168217635806164	1.14238486388429	0.779024454454407	0.208101012171972	0.147251282054103	0.215933703806482	0.943193417010806	NA	NA	0.0201889873448831	0.824648589159843	86.3664859657851
a10363	loss_cnaOV1	1059	AZD8055	MTORC1/2	3	30	0.693147180559945	NA	0.447608606215787	0.26447562113642	0.183132985079367	0.797897692014462	1.16700172267901	0.159693325378199	0.229519381885926	0.156926062336018	0.94365616588521	NA	NA	0.14917422595173	0.742616416484843	86.3732888594526
a10364	ARID1A_mut	225	Genentech Cpd 10	AURKA, AURKB	8	24	2.32630161961136	NA	2.51819870144822	2.95280377658813	-0.434605075139901	1.85790380638693	1.85822039831812	0.23389171291249	0.233922269627661	0.233882415419217	0.943707365964282	NA	NA	0.349297424089744	0.577212862024578	86.3732888594526
a10365	loss_cnaOV52, loss_cnaOV53	329	QL-XI-92	DDR1	8	24	2.32630161961136	NA	4.6020744847564	4.51087440686821	0.0912000778881925	1.01985473967818	1.02623399131136	0.0889974748192946	0.0894245762067754	0.0888686972565133	0.943711946626188	NA	NA	0.19405419989325	0.830526848283635	86.3732888594526
a10366	loss_cnaOV81_(RB1)	282	EKB-569	EGFR	4	28	0.916290731874155	2.99573227355399	1.73351078354152	1.67647929884094	0.0570314847005802	1.28150489351397	1.5182202993027	0.0381166635303965	0.0445035247147562	0.0375646964585931	0.943766175073527	NA	NA	0.329411464937245	0.938893930966574	86.3732888594526
a10367	gain_cnaOV72_(ASXL1)	186	Bexarotene	Retinioic acid X family agonist	4	14	2.07944154167984	NA	3.78504651450182	3.77816626168074	0.00688025282107851	1.37961406204381	0.881152337687243	0.00692287585955046	0.00498708516415516	0.00780824441677938	0.943849017812407	NA	NA	0.810193184143253	0.992951897360325	86.3732888594526
a10368	PIK3CA_mut	290	KIN001-260	IKK	6	25	2.99573227355399	NA	4.75042555629618	4.8742034287724	-0.123777872476223	0.89529510181041	0.910788423390315	0.136298825138803	0.138253713469366	0.135901894773182	0.943855559110267	NA	NA	0.667384937757282	0.769850563989181	86.3732888594526
a10369	loss_cnaOV82	1010	Gefitinib	EGFR	3	27	-0.693147180559945	NA	0.980711922844398	0.919283125428854	0.0614287974155443	1.38012909094938	1.27266755282688	0.047967172351031	0.044509457715501	0.0482677485405336	0.94390493026491	NA	NA	0.957757886845968	0.94696445727971	86.3732888594526
a10370	gain_cnaOV26	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	3.8384846934091	3.76793730942069	0.0705473839884023	1.61463039969914	0.869204476764564	0.0710120524909076	0.0436925899583879	0.0811631622641896	0.944218219623862	NA	NA	0.810193601202596	0.947406043045602	86.3936249083406
a10371	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	261	TL-1-85	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	3.50483244866062	3.56499983046514	-0.0601673818045119	1.18811769982614	0.92895135050706	0.0621868219236434	0.0506409270843423	0.0647691418626713	0.944598585648204	NA	NA	0.730094710258049	0.918747946701062	86.414617575454
a10372	loss_cnaOV39	185	OSI-906	IGF1R	4	14	0.940007258491471	NA	2.20346635186083	2.20942027613764	-0.00595392427681007	1.40765787845574	1.30546701876396	0.00449275403496069	0.0042296671428016	0.00456076192751875	0.944692785053684	NA	NA	0.689477911227199	0.994270859805115	86.414617575454
a10373	loss_cnaOV21, loss_cnaOV22	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	3	29	1.63315443905142	NA	2.76915492711241	2.87355481859015	-0.104399891477743	1.08101169341516	0.786330287188888	0.128996931660458	0.0965760982176981	0.132768498401569	0.944993128607344	NA	NA	0.0201896202256616	0.884229545807858	86.414617575454
a10374	gain_cnaOV51_(MYC)	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	3.44808379215164	3.27364768053487	0.174436111616775	0.470175371303353	1.09921451256925	0.176568843246782	0.37100223079152	0.1586916017048	0.945036808257318	NA	NA	0.194706219674675	0.635732795707499	86.414617575454
a10375	gain_cnaOV72_(ASXL1)	190	Bleomycin	DNA damage	4	15	4.15888308335967	NA	1.72679990774422	1.65070053118828	0.0760993765559306	1.53748663508098	2.49300644611908	0.0323447981171985	0.0494959597173489	0.0305251423133688	0.945076208028082	NA	NA	0.617347005953678	0.941397607293257	86.414617575454
a10376	loss_cnaOV54	163	JQ1	BRD4	6	13	0.940007258491471	NA	-0.0401222353804257	0.147880342928236	-0.188002578308661	0.844554842544885	2.17915051701816	0.0996158811976433	0.222605529964349	0.0862733330444355	0.945101804129913	NA	NA	0.586187236532756	0.79030406345248	86.414617575454
a10377	loss_cnaOV1	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.76475821160541	8.74795581351841	0.0168023980870053	1.0446192437545	1.25922454337133	0.0134892735285597	0.0160847104698314	0.0133434486926535	0.945124820374575	NA	NA	0.532568995899385	0.981139919661546	86.414617575454
a10378	PIK3R1_mut	345	KIN001-270	CDK9	5	27	2.99573227355399	NA	5.05835527872687	5.21532603281576	-0.156970754088892	0.851561476827224	0.763099771606573	0.202418080565351	0.184332850135188	0.205701482203851	0.945286473834932	NA	NA	0.336586567384274	0.715611142548498	86.414617575454
a10379	loss_cnaOV21, loss_cnaOV22	1175	AG-014699	PARP1, PARP2	3	30	1.6094379124341	NA	4.02270404015339	3.88900332168171	0.133700718471678	1.04295243816277	1.08539390639319	0.123487561966305	0.128194454108761	0.12318174782828	0.945300373573005	NA	NA	0.319292806756077	0.849210589453524	86.414617575454
a10380	loss_cnaOV83	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.36536662010937	3.25967687912595	0.105689740983426	1.18540296144803	1.02654325123767	0.100741777469951	0.0891593360407334	0.102956929341262	0.945399553600275	NA	NA	0.0938760221889083	0.858912155853501	86.414617575454
a10381	PTEN_mut	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	3.7659450236916	3.89772201840056	-0.131776994708957	1.00807929452483	1.63917432791745	0.0821734736322999	0.1307208623614	0.0803923002359234	0.945449478797751	NA	NA	0.71735581116714	0.853362637317545	86.414617575454
a10382	gain_cnaOV4_(KRAS)	299	OSI-027	MTORC1/2	8	24	2.99573227355399	NA	1.57211882949465	1.51736389709435	0.0547549324002961	2.04216229182741	1.90053940225605	0.0283042561437643	0.0268122335915326	0.0288102063736741	0.946050586863841	NA	NA	0.783921659413826	0.947901388446291	86.4455940713721
a10383	loss_cnaOV43_(NF1)	226	GSK1070916	AURKB	5	27	0.940007258491471	2.32630161961136	2.33227261274886	2.31058048680985	0.021692125939015	0.624605619996535	1.5448412260751	0.0148969925681507	0.0347293159788338	0.0140416539725102	0.946305166535987	NA	NA	0.822041403338292	0.958285611998865	86.4455940713721
a10384	PIK3CA_mut	1494	SN-38	TOP1	6	26	-2.99573227355399	NA	-4.54721751332409	-4.09949710943338	-0.447720403890715	1.04820993481203	1.38907093942698	0.334543299500141	0.427128563679376	0.322316442726395	0.946319983082321	NA	NA	0.220541218425471	0.39911001077599	86.4455940713721
a10385	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1022	AZD7762	CHEK1, CHEK2	8	23	0.693147180559945	NA	-0.77411221990708	-0.82980824715727	0.0556960272501901	0.963057432007421	0.759120554243007	0.0685031093170099	0.0578325086325287	0.0733691466248467	0.946344818570565	NA	NA	0.0806057676312067	0.884973245010291	86.4455940713721
a10386	loss_cnaOV52, loss_cnaOV53	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	5	14	2.77258872223978	NA	-0.906357995033299	-0.449028547002891	-0.457329448030408	0.514373244283965	2.12793350824812	0.243587255169091	0.889100382091287	0.214917170230059	0.94636847737925	NA	NA	0.0447612038496065	0.466669430364861	86.4455940713721
a10387	ARID1A_mut	290	KIN001-260	IKK	8	23	2.99573227355399	NA	4.75618301081774	4.88296412915414	-0.126781118336393	0.928069150636067	0.901164987953055	0.139667989279445	0.136607405008023	0.140685801192043	0.946407485120394	NA	NA	0.667387437341114	0.743221576296552	86.4455940713721
a10388	loss_cnaOV58	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	3.2731430261372	3.39398219105296	-0.120839164915755	1.98938954034728	1.62952594365246	0.0718441610117354	0.060741831835841	0.0741560239568222	0.946426141497203	NA	NA	0.631896793603724	0.903022580289841	86.4455940713721
a10389	MLL2_mut	1003	Camptothecin	TOP1	3	28	-2.30258509299405	NA	-4.48499262830768	-3.60611525712045	-0.878877371187228	2.25921813964454	1.67621383983114	0.510154573350647	0.389018375766719	0.524322941562019	0.946658049051291	NA	NA	0.248175504647795	0.573414446129791	86.4584533535665
a10390	loss_cnaOV38	299	OSI-027	MTORC1/2	8	24	2.99573227355399	NA	1.53414364646737	1.53002229143678	0.00412135503058542	2.38969822239548	1.77315025204786	0.00213026648091872	0.00172463409478293	0.00232431235075852	0.946922035811166	NA	NA	0.783922201847328	0.996513213220471	86.4634300437953
a10391	gain_cnaOV72_(ASXL1)	310	YM201636	FYV1	5	27	1.63315443905142	NA	2.39738821377962	2.34942182301929	0.0479663907603309	0.401482994436798	0.92621605588451	0.0548416764485153	0.119473032295224	0.0517874749153689	0.946995180442156	NA	NA	0.652594422025187	0.852408440193168	86.4634300437953
a10392	loss_cnaOV43_(NF1)	155	AP-24534	ABL	3	16	-0.669430653942629	NA	0.777968953864842	0.790534944515618	-0.012565990650776	1.97887286075977	1.14947395866933	0.00985289728233877	0.0063500747824453	0.0109319489632656	0.947078162864089	NA	NA	0.588428410973764	0.992357782678414	86.4634300437953
a10393	loss_cnaOV1	1043	JNK Inhibitor VIII	JNK	3	30	2.30258509299405	NA	4.4721399881581	4.43902577591419	0.033114212243909	0.83100226170086	1.0294312409568	0.032535169142298	0.0398485224048996	0.0321674832921636	0.947285799711503	NA	NA	0.377782405485019	0.953282935040955	86.4634300437953
a10394	ARID1A_mut	1007	Docetaxel	Microtubules	9	22	-4.38202663467388	NA	-5.07968964168528	-4.47220989884632	-0.607479742838961	0.836988650979449	1.56746452290114	0.432545554000837	0.725792090643146	0.387555656899085	0.947334253997062	NA	NA	0.137884784301666	0.174437904620561	86.4634300437953
a10395	loss_cnaOV54	263	FR-180204	ERK	10	22	2.99573227355399	NA	4.78354952201914	4.8245905610301	-0.041041039010957	0.727449827492028	0.763910453691258	0.0544919653695255	0.0564176902102665	0.0537249343985861	0.947426393084755	NA	NA	0.766631094010757	0.885820823384422	86.4634300437953
a10396	loss_cnaOV59	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	4	29	-2.30258509299405	NA	-0.391709346432503	-0.324409039841081	-0.0673003065914214	2.11131714012097	1.32295567572158	0.0474437495316708	0.0318759817331684	0.050871172652639	0.947509539274436	NA	NA	0.889638106141552	0.954028744906872	86.4634300437953
a10397	loss_cnaOV56	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.766841978482	8.74773255278163	0.0191094257003748	1.04334738724288	1.25929934751036	0.0153414359053025	0.0183154967693673	0.0151746490920957	0.947530475523928	NA	NA	0.532572005851703	0.978527604926188	86.4634300437953
a10398	SMARCA4_mut	1170	CCT018159	HSP90	3	30	2.30258509299405	NA	3.59806940041164	3.70464809788183	-0.106578697470197	1.32686134901252	1.22713453256324	0.0863816491985528	0.080323914438773	0.0868516814106564	0.947532678160687	NA	NA	0.200814692972007	0.904329855730705	86.4634300437953
a10399	loss_cnaOV56	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.8650342009971	4.05003359204924	-0.184999391052143	1.50128430802981	1.509470632227	0.122603334620554	0.12322741939195	0.12255911913914	0.947654204735453	NA	NA	0.33272065432877	0.854796112235517	86.4643532788754
a10400	PIK3CA_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	7	24	2.30258509299405	NA	4.61455663072254	4.48165467883338	0.132901951889164	0.593995578771075	0.996830099488526	0.143221728600985	0.223742325092935	0.133324577535687	0.94793500169588	NA	NA	0.531078554416837	0.666481009093987	86.4643532788754
a10401	loss_cnaOV38	1026	17-AAG	HSP90	8	25	0	NA	-0.171619297742947	-0.645780273665121	0.474160975922174	2.10137464031042	2.36244028797114	0.205613877657716	0.225643236968031	0.200708131475942	0.947944698212374	NA	NA	0.0627746890411649	0.599186518169079	86.4643532788754
a10402	gain_cnaOV95_(MECOM)	1001	AICAR	AAPK1 (AMPK) agonist	8	23	7.60090245954208	NA	8.78888000212626	8.73591293027485	0.0529670718514055	1.22634942167008	1.25139005440493	0.0425304464038055	0.0431908483140745	0.0423265884725229	0.947952480666792	NA	NA	0.532572519872196	0.918303052852759	86.4643532788754
a10403	KRAS_mut	265	Tubastatin A	HDAC6	7	24	2.99573227355399	NA	4.86674765243943	4.7240609261919	0.142686726247531	0.822383505010443	1.32385816146889	0.115358374044754	0.173503876692808	0.107780977147289	0.948132619876285	NA	NA	0.427840261015466	0.733504892852622	86.4643532788754
a10404	ARID1A_mut	255	CP724714	ERBB2	8	24	2.32630161961136	NA	4.45334592961652	4.40231075898423	0.0510351706322867	0.57088972052895	1.04778574630132	0.0532734432103016	0.089395847914376	0.048707639717796	0.948289208880352	NA	NA	0.787756140913075	0.863757523636249	86.4643532788754
a10405	loss_cnaOV52, loss_cnaOV53	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.03997021670796	3.11870035491304	-0.0787301382050791	1.28559626424636	0.848771191918986	0.0812131009643223	0.0612401734468573	0.0927577879111074	0.948442053655575	NA	NA	0.674422438758256	0.903329743761491	86.4643532788754
a10406	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1050	ZM-447439	AURKB	4	18	1.38629436111989	0.693147180559945	2.6289715666763	2.40833826698425	0.220633299692045	2.20481629627232	1.46582807341927	0.138016187293824	0.100068790340977	0.150517856556931	0.948537985783291	NA	NA	0.231787838755159	0.858788573610368	86.4643532788754
a10407	loss_cnaOV33_(ZFHX3)	235	QL-XII-47	BTK, BMX	4	28	2.32630161961136	NA	1.70858636146405	1.54481777984621	0.16376858161784	1.36701081545621	1.66069839816223	0.10024353498603	0.119800501770855	0.0986142828818707	0.948728028127804	NA	NA	0.0806131807584887	0.837408666000865	86.4643532788754
a10408	gain_cnaOV94	1013	Nilotinib	ABL	4	17	0.693147180559945	NA	3.29445082964144	3.23870100828894	0.0557498213525021	1.60740696641323	0.897799953306031	0.0534787706770267	0.0346830780986985	0.0620960394876505	0.94883899781058	NA	NA	0.56940208287777	0.950312297529795	86.4643532788754
a10409	loss_cnaOV59	1009	ATRA	Retinoic acid and retinoid X receptor agonist	4	27	2.30258509299405	NA	4.49268371508452	4.51447680913781	-0.0217930940532858	1.41752229139904	0.855690429400404	0.0234412080773372	0.0153740750219715	0.02546843262996	0.948890311698318	NA	NA	0.531079705486735	0.977812193716271	86.4643532788754
a10410	PIK3CA_mut	1018	ABT-888	PARP1, PARP2	7	24	1.6094379124341	NA	4.11564735490587	4.35323329851642	-0.237585943610547	0.802385999127262	0.801324331500895	0.296410319713226	0.296099313633294	0.296491613034568	0.948901334798096	NA	NA	0.228042732471948	0.506527521266881	86.4643532788754
a10411	loss_cnaOV36	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.685828503183652	0.552835902701861	0.13299260048179	1.92812883917061	1.15262724651111	0.108830703958469	0.0689749552934428	0.115382141871404	0.948940587271793	NA	NA	0.43387593657626	0.916686444435792	86.4643532788754
a10412	loss_cnaOV82	1030	KU-55933	ATM	3	30	2.30258509299405	NA	4.23646387715185	4.14244783152859	0.0940160456232642	1.81763658624595	0.961026877008598	0.0905871782959299	0.0517243360607303	0.0978287370233695	0.949222288522525	NA	NA	0.532158571527593	0.937254867712185	86.4643532788754
a10413	PIK3CA_mut	1199	Tamoxifen	ER	7	25	1.6094379124341	NA	3.89299231464019	4.00416414641304	-0.111171831772855	0.658551945507823	0.791002731538472	0.145067388624618	0.16881254778942	0.140545446103113	0.949291147726611	NA	NA	0.528152625911889	0.713159900665433	86.4643532788754
a10414	loss_cnaOV85	273	CUDC-101	HDAC, EGFR	7	24	1.63315443905142	NA	-0.000882033970106333	0.152769554316963	-0.153651588287069	1.22074929571212	1.7275279900958	0.0939413921292257	0.125866620465619	0.0889430383576877	0.949303643703676	NA	NA	0.464753675425835	0.795231001725706	86.4643532788754
a10415	NF1_mut	288	KIN001-055	JAK3, MNK1	4	28	2.32630161961136	NA	3.74407426997014	3.80911824799652	-0.0650439780263894	0.947284493420102	1.04918566153987	0.0625756693044947	0.0686636152900094	0.0619947263965897	0.949349832095134	NA	NA	0.71888041260202	0.905127011304287	86.4643532788754
a10416	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.45160957617461	3.46671845521377	-0.0151088790391651	1.34910811753827	1.09346394148671	0.0134115795826246	0.011199161018121	0.0138174460683381	0.949350707448472	NA	NA	0.775531597610418	0.98674780409392	86.4643532788754
a10417	gain_cnaOV72_(ASXL1)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	NA	1.28164005967543	1.20434853550543	0.0772915241700014	1.15813518776007	1.26128208854059	0.0619099001681651	0.0667379119353841	0.0612801250982913	0.949481108938582	NA	NA	0.269790094540229	0.896721643405162	86.4643532788754
a10418	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	287	KIN001-244	PDPK1 (PDK1)	7	25	2.99573227355399	NA	3.56791100015145	3.5377819410137	0.030129059137745	0.878950542071126	0.91946884617037	0.0330540342294768	0.034278446505932	0.032767895577141	0.949580866055608	NA	NA	0.665244386731166	0.938321208958142	86.4643532788754
a10419	loss_cnaOV42	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.51844623217057	4.51593156819923	0.00251466397133893	0.671990083655401	0.598954762165182	0.00416267171680364	0.0037421147015444	0.00419842053220945	0.949602203546602	NA	NA	0.617255722014694	0.995519956691105	86.4643532788754
a10420	gain_cnaOV51_(MYC)	155	AP-24534	ABL	5	14	-0.669430653942629	NA	0.700585805314925	0.819966924804985	-0.119381119490059	1.45086712885038	1.21462440267095	0.0936941474033039	0.0822825999129589	0.0982864490681575	0.949646384202498	NA	NA	0.588433387785001	0.874590172246624	86.4643532788754
a10421	gain_cnaOV26	1061	SB590885	BRAF	3	30	1.6094379124341	NA	3.91844484753434	3.9284493219284	-0.0100044743940604	1.24129171894513	1.29749889144974	0.007731753914833	0.0080597286208937	0.0077105841553992	0.949704734233761	NA	NA	0.575449166421663	0.99042418015312	86.4643532788754
a10422	RB1_mut	1011	ABT-263	BCL2, BCL2L1, BCL2L2	3	30	0.693147180559945	NA	1.9797554252867	1.7135917578344	0.266163667452304	2.07678874614503	1.68494894603516	0.155384481613052	0.128161166101444	0.157965419711149	0.949729853488663	NA	NA	0.232026834485779	0.847545295676127	86.4643532788754
a10423	gain_cnaOV49	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	2.52204430957569	2.43112870186461	0.0909156077110778	0.938619850927195	1.50078824310882	0.0618467586544187	0.0968609470823239	0.0605785713797637	0.950291558035246	NA	NA	0.243004985444901	0.890359289957173	86.4983389318322
a10424	loss_cnaOV1	196	Phenformin	AAPK1 (AMPK) agonist	3	28	8.29404964010203	NA	8.68566322948052	8.76520632178379	-0.0795430923032718	2.37141988761749	1.66529599529801	0.0461572033446421	0.0335423906658669	0.047765137565852	0.950396166846366	NA	NA	0.922298885607278	0.959544166819095	86.4983389318322
a10425	loss_cnaOV34	1031	Elesclomol	HSP70	5	26	-1.6094379124341	NA	-4.12030111239198	-4.04813289418689	-0.0721682182050909	1.56446142764634	1.53284165811358	0.0469465663273593	0.0461297523414589	0.047081326256429	0.950474716090661	NA	NA	0.864957655225582	0.927805395437258	86.4983389318322
a10426	gain_cnaOV26	135	Gemcitabine	DNA replication	3	16	0.0237165266173161	NA	-2.43868588455449	-2.12246057835441	-0.316225306200079	2.53427269353894	2.71323905343215	0.117433569985522	0.124779510510565	0.116549002860646	0.950518657973729	NA	NA	0.422067236296717	0.857340622232882	86.4983389318322
a10427	loss_cnaOV56	269	NSC-207895	MDM4	3	28	2.99573227355399	NA	3.98153173803577	3.87462344186369	0.106908296172085	1.98775224242331	1.57165059192677	0.066658667636864	0.0537835117930749	0.0680229414357428	0.950617241469314	NA	NA	0.71735996194	0.935461867778875	86.4983389318322
a10428	gain_cnaOV26	254	AC220	FLT3	3	29	0.0237165266173161	NA	2.48116250009776	2.51388742965422	-0.0327249295564553	0.645093379077534	0.633765955074794	0.0515737053328488	0.0507289806682733	0.0516356697522404	0.950734601692209	NA	NA	0.858982955251049	0.939666450886757	86.4983389318322
a10429	loss_cnaOV70	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	0.787407449549204	0.68670854520137	0.100698904347834	1.4735066115629	2.3789206386267	0.0432270647261562	0.0683396352331435	0.0423296610709828	0.950778478672497	NA	NA	0.946177301743262	0.922565726211465	86.4983389318322
a10430	loss_cnaOV38	265	Tubastatin A	HDAC6	8	23	2.99573227355399	NA	4.70997111228264	4.7723881259748	-0.062417013692162	1.24109557472281	1.23716467515834	0.0504129511814553	0.0502918670917848	0.0504516617273876	0.950832459839823	NA	NA	0.427843828458498	0.904398867393641	86.4983389318322
a10431	loss_cnaOV42	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	1.42160474004727	1.43490662643916	-0.0133018863918941	1.44841859972827	1.84219403137196	0.00736764656366573	0.00918373072148456	0.00722067608805986	0.95096415183448	NA	NA	0.616924901012349	0.987532264458437	86.5020255276615
a10432	TP53_mut	164	JQ12	HDAC	12	7	1.63315443905142	NA	1.80217553846752	1.77969451860486	0.0224810198626673	2.2654569942296	2.20423235102114	0.0100181054920187	0.00992339290479988	0.0101990245503168	0.951139671057173	NA	NA	0.663990347424265	0.983388366602456	86.5096976664243
a10433	gain_cnaOV19	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.8758214196867	-2.7231608129765	-0.152660606710195	0.776416527421404	1.29152560781026	0.122908971619801	0.196622046695997	0.118201765251118	0.951476430732707	NA	NA	0.384210661469275	0.794645900841106	86.5320323488422
a10434	loss_cnaOV85	260	NG-25	MAP3K7 (TAK1)	7	25	2.32630161961136	NA	2.93221600393331	3.03431613759664	-0.102100133663321	1.39508709327532	0.999211264378334	0.0936741003087608	0.073185490823813	0.102180727242745	0.951581973684303	NA	NA	0.437383101731504	0.860930089043253	86.533336758471
a10435	TP53_mut	330	XMD13-2	RIPK	22	10	2.32630161961136	NA	4.07409951805391	4.10585209235392	-0.0317525743000093	1.21350455329229	0.903314493331283	0.0281138452604578	0.026166011667499	0.0351511843709169	0.951805003476895	NA	NA	0.820741726192616	0.935046147520503	86.5433382376222
a10436	gain_cnaOV50	208	SB-715992	KIF11	4	28	-2.05572501506252	NA	-1.04290644291623	-1.35661228534972	0.313705842433489	0.454505493517252	1.98039120391266	0.166488114921767	0.69021353296708	0.158405996660508	0.95198053578441	NA	NA	0.0758582644494492	0.480994335245506	86.5433382376222
a10437	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.45369816389758	3.46632684501572	-0.0126286811181409	1.34821114353403	1.09361673717607	0.0112099566902569	0.00936699060730032	0.011547629703209	0.952049679943424	NA	NA	0.77553454156849	0.988916210167666	86.5433382376222
a10438	gain_cnaOV4_(KRAS)	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	7	25	2.99573227355399	NA	3.99244207177371	4.04395929080014	-0.0515172190264286	2.03097081868159	1.34838226018319	0.0341220310263793	0.0253658095687811	0.03820668704098	0.952143116637047	NA	NA	0.332726564473049	0.951158685283899	86.5433382376222
a10439	loss_cnaOV84	276	CAY10603	HDAC6	6	25	2.99573227355399	NA	1.40910542622411	1.43897061266807	-0.0298651864439545	1.74527813007097	1.81768764841613	0.0165420480532465	0.0171119925984175	0.0164303181957461	0.952148010312687	NA	NA	0.616926052122193	0.971150777245703	86.5433382376222
a10440	gain_cnaOV96	260	NG-25	MAP3K7 (TAK1)	5	27	2.32630161961136	NA	2.92737008473671	3.0276505571765	-0.100280472439791	0.985723707512824	1.10536702673028	0.0919857917004237	0.101732840222356	0.0907214255670575	0.95228819481714	NA	NA	0.437383952153342	0.844411338399751	86.5461391825115
a10441	loss_cnaOV39	1494	SN-38	TOP1	10	22	-2.99573227355399	NA	-4.09197195285672	-4.2250231998475	0.133051246990782	1.84508528382207	1.0678888911198	0.0986357284321652	0.072111163726355	0.124592781231447	0.952361253460901	NA	NA	0.220548822134912	0.835383258932435	86.5461391825115
a10442	SMARCA4_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.11189852750231	4.02449590310043	0.0874026244018786	1.54883561482555	1.50689190070318	0.0578930990740535	0.0564311819571137	0.0580019206162651	0.952674423116405	NA	NA	0.332727228775077	0.93287503157284	86.5553524896483
a10443	KRAS_mut	155	AP-24534	ABL	3	16	-0.669430653942629	NA	0.871800462726501	0.772941536604057	0.0988589261224436	1.04198409794949	1.3027017722976	0.0775485986658242	0.0948756572360245	0.0758876115966926	0.952718283078347	NA	NA	0.588439013821098	0.893463109107551	86.5553524896483
a10444	loss_cnaOV52, loss_cnaOV53	344	THZ-2-49	CDK9	8	24	2.99573227355399	NA	2.68313134166258	2.55526970011073	0.127861641551855	2.39018991076082	2.34148868192079	0.0543411678923738	0.0534943441005303	0.0546069868025015	0.952753366815007	NA	NA	0.388915160301041	0.897435916159044	86.5553524896483
a10445	loss_cnaOV38	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	8	25	0.693147180559945	NA	2.78338031124687	2.80250172938349	-0.0191214181366162	1.16403468303326	0.905573104484992	0.0197133291265272	0.0164268457077149	0.0211152672731935	0.95284791926771	NA	NA	0.966398206520614	0.966927537053032	86.5553524896483
a10446	gain_cnaOV26	1069	EHT 1864	Rac GTPases	3	30	2.30258509299405	NA	4.28921050392773	4.22333585917861	0.065874644749119	1.40062846786395	0.950886541413496	0.0668024315974518	0.0470322046570866	0.0692770818390132	0.953003201888225	NA	NA	0.212281669751286	0.943210903623374	86.5553524896483
a10447	loss_cnaOV21, loss_cnaOV22	275	I-BET	BRD2, BRD3, BRD4	3	28	2.99573227355399	NA	3.84582922059791	3.92778913532309	-0.0819599147251759	1.02442505827522	1.24542454788795	0.066555229977908	0.0800057691513018	0.0658088158485134	0.953009977388291	NA	NA	0.7006097173072	0.906599439347829	86.5553524896483
a10448	ARID1A_mut	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.42017132682361	2.51788356339092	-0.0977122365673102	0.682957956504892	0.809113259457149	0.125069341366879	0.143072111008652	0.120764596828962	0.953247800346145	NA	NA	0.752014401669827	0.800325131470558	86.568665854175
a10449	ARID1A_mut	1192	GSK269962A	ROCK1, ROCK2	9	23	1.6094379124341	NA	2.1187881343882	2.56520748144812	-0.446419347059923	1.13401448478234	1.55612641146504	0.306694769209465	0.39366282622537	0.286878587607567	0.954051303474013	NA	NA	0.24300955630865	0.380767048992934	86.6301534357891
a10450	MLL2_mut	1192	GSK269962A	ROCK1, ROCK2	3	29	1.6094379124341	NA	1.69399724608252	2.51678874291562	-0.822791496833108	0.853056987270153	1.48269480505049	0.567734291601424	0.964521138811726	0.554929776532865	0.954206776828114	NA	NA	0.243009737551939	0.229998686291891	86.6301534357891
a10451	loss_cnaOV34	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	5	27	2.32630161961136	NA	5.25117751485946	5.1223023886563	0.128875126203162	0.796809133271804	0.550885718897587	0.218568804912316	0.161739017315205	0.23394167207867	0.954268512928714	NA	NA	0.0123725168856614	0.743732885202157	86.6301534357891
a10452	PIK3R1_mut	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.43507796404126	4.39078795759926	0.0442900064419938	0.674662133173872	0.892424679776946	0.0510604303132349	0.0656476838764263	0.0496288453755713	0.954290077277109	NA	NA	0.870303559584915	0.90175448222768	86.6301534357891
a10453	KRAS_mut	1218	JQ1	BRD2, BRD3, BRD4	7	24	0	NA	2.30662437613872	2.29029915773966	0.0163252183990603	0.633606149716679	0.967149150866484	0.0179744421351047	0.0257655617868612	0.0168797319259747	0.954627942375614	NA	NA	0.596783103441505	0.958739570858845	86.6497820960001
a10454	SMAD4_mut	152	CP466722	ATM	3	29	2.77258872223978	NA	2.65381500438541	2.64620306576783	0.00761193861757992	0.765974603476469	0.824365516417943	0.00927604130134459	0.00993758615890424	0.00923369362980579	0.954720511384187	NA	NA	0.558381889392913	0.988228343682791	86.6497820960001
a10455	gain_cnaOV4_(KRAS)	1149	TW 37	BCL2, BCL2L1	7	26	1.6094379124341	NA	-0.749426429282321	-0.737960186030762	-0.0114662432515592	0.551826108303761	1.0009906961101	0.0123144374771588	0.0207787255423722	0.0114548949317087	0.954954703668177	NA	NA	0.0431135455418157	0.968509168401635	86.6497820960001
a10456	gain_cnaOV50	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	2.74269581587442	2.87202935837279	-0.129333542498371	1.2961367648542	1.05366111281929	0.119713330076537	0.0997838700400722	0.122746811972886	0.955204783958062	NA	NA	0.309799669883083	0.85900355981458	86.6497820960001
a10457	TP53_mut	276	CAY10603	HDAC6	21	10	2.99573227355399	NA	1.42740869450293	1.44533152894848	-0.0179228344455451	1.82222859460273	1.76753119589938	0.00992717837638984	0.00983566743416873	0.0101400385391361	0.955870066523051	NA	NA	0.61692948712336	0.979437794038775	86.6497820960001
a10458	gain_cnaOV19	279	BIX02189	MAP2K5 (MEK5)	3	29	2.99573227355399	NA	4.42189660276745	4.43214368537147	-0.010247082604022	0.387623076585841	0.763026304716906	0.013774503723172	0.0264356877156995	0.0134295273186208	0.955903072413714	NA	NA	0.526941465534731	0.971048791555517	86.6497820960001
a10459	loss_cnaOV52, loss_cnaOV53	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	23	3.68887945411394	NA	3.44320881736383	3.50575070545694	-0.0625418880931075	0.696488562181807	1.22807617228295	0.055689743648416	0.0897960016704222	0.0509267173361439	0.956189852512548	NA	NA	0.728498819771047	0.861861360778406	86.6497820960001
a10460	gain_cnaOV51_(MYC)	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	8.71398062924433	8.77020426223656	-0.0562236329922321	1.62851484718249	1.74719159159927	0.0326254032275395	0.0345244828989464	0.0321794319882048	0.956220864196219	NA	NA	0.922300091181946	0.938505298466926	86.6497820960001
a10461	SMARCA4_mut	330	XMD13-2	RIPK	3	29	2.32630161961136	NA	4.02060036027017	4.09058307723844	-0.0699827169682656	1.74799539740412	1.0715625010148	0.061968122055429	0.0400359846897733	0.0653090388120058	0.95623232327036	NA	NA	0.820743705607867	0.951541893968058	86.6497820960001
a10462	gain_cnaOV72_(ASXL1)	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	3.30854994576237	3.24049639017972	0.0680535555826465	1.15837097312042	1.08560840616661	0.0621159351957282	0.0587493619589964	0.0626870197357353	0.956483226873019	NA	NA	0.0639430719986437	0.907448845766594	86.6497820960001
a10463	loss_cnaOV85	282	EKB-569	EGFR	7	25	0.916290731874155	2.99573227355399	1.8097482869575	1.64828901972039	0.161459267237111	1.2330298798489	1.55333263576803	0.108015910034964	0.130945137563817	0.103943780951515	0.956517337533481	NA	NA	0.329428174542628	0.778087617287567	86.6497820960001
a10464	loss_cnaOV57_(ZNRF3)	1219	PFI-1	BRD2, BRD3, BRD4	4	28	2.30258509299405	NA	2.30420291991263	2.36978327712271	-0.0655803572100795	0.547379257864075	0.906870208145268	0.0747292208024329	0.119807896020723	0.0723150420215088	0.956560107573541	NA	NA	0.610162679415972	0.846103456338749	86.6497820960001
a10465	loss_cnaOV55	291	KIN001-266	MAP3K8 (COT)	7	25	2.99573227355399	NA	3.28670982689325	3.30684597454811	-0.0201361476548612	0.764225615058005	1.18788005851821	0.0180416989711329	0.0263484333135481	0.0169513306587363	0.956568208787529	NA	NA	0.951233345761093	0.95776715656143	86.6497820960001
a10466	NF1_mut	1020	Lenalidomide	TNFA	4	27	1.6094379124341	NA	4.35157017931631	4.40708852543343	-0.0555183461171254	0.983055618887745	0.750942890955252	0.0713445839935973	0.0564752848673408	0.0739315156795773	0.956612890502317	NA	NA	0.0443612846878792	0.919568731864582	86.6497820960001
a10467	loss_cnaOV34	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	5	27	2.99573227355399	NA	3.88605280144866	4.05984491722874	-0.173792115780078	1.43694210880205	1.51926310461725	0.115205007291105	0.120945802002396	0.114392375653631	0.956652367916742	NA	NA	0.332731965820022	0.814051429214287	86.6497820960001
a10468	gain_cnaOV95_(MECOM)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	5	14	0.940007258491471	NA	2.43773511291819	2.385170427461	0.0525646854571975	1.0703822468659	0.975114290677418	0.0526516401226164	0.049108330795945	0.053906178957423	0.956773925630695	NA	NA	0.415383233957992	0.92605453489406	86.6497820960001
a10469	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.14670265723843	3.83784058844712	0.308862068791309	1.6814123162713	1.48692304089919	0.203703245731662	0.183692046146207	0.207718933862596	0.956931338134773	NA	NA	0.072022976465521	0.750457612689339	86.6497820960001
a10470	TP53_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	22	10	2.99573227355399	NA	5.70934423133441	5.72767762318527	-0.018333391850863	0.531831192265519	0.337500742550091	0.0380492593779554	0.0344722011748984	0.0543210415252405	0.956932200244801	NA	NA	0.384676645090255	0.907168228812053	86.6497820960001
a10471	SMARCA4_mut	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.11939390481741	3.24111034848427	-0.121716443666863	1.57251241491701	1.21343030581709	0.0981104108464998	0.0774025327318553	0.100307733442426	0.956995101826677	NA	NA	0.603199867519716	0.907176516216442	86.6497820960001
a10472	gain_cnaOV94	231	FMK	RSK	3	17	2.99573227355399	2.32630161961136	5.3714516035927	5.22016195845335	0.15128964513935	0.308802570751782	0.788408549375237	0.20160877989553	0.48992352871621	0.191892446193331	0.957014047290271	NA	NA	0.130312898690223	0.578855094460504	86.6497820960001
a10473	loss_cnaOV55	306	TG101348	JAK2	7	25	2.32630161961136	NA	2.84514746251619	2.81815374184755	0.026993720668639	1.38686194362953	1.41369669067599	0.0191666311307366	0.019463884485859	0.0190944216299547	0.957037857728982	NA	NA	0.629602927098045	0.964760263579979	86.6497820960001
a10474	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.77678908148242	2.92912549574518	-0.152336414262761	1.08255621884162	1.28140196848646	0.121218587872124	0.140719171541749	0.118882612957661	0.957368248536459	NA	NA	0.234468229505654	0.788195324765476	86.6497820960001
a10475	SMARCA4_mut	333	T0901317	LXR	3	29	2.32630161961136	NA	4.44646963620378	4.78509817712012	-0.338628540916345	1.22950835392528	1.11630100312635	0.301216574220156	0.27541784473058	0.303348774181847	0.957420939586242	NA	NA	0.00536060777592658	0.685867755040917	86.6497820960001
a10476	PIK3CA_mut	176	IPA-3	PAK1, PAK2, PAK3	5	14	3.46573590279973	NA	4.19347543650071	4.96325065159404	-0.769775215093325	1.19847171091398	1.64360111284915	0.496499370574321	0.642297359281244	0.468346735150925	0.957769213618718	NA	NA	0.125610508237218	0.293117321305978	86.6497820960001
a10477	loss_cnaOV56	292	Masitinib	KIT	3	29	2.99573227355399	NA	4.15787792903841	3.99858688500019	0.159291044038211	0.52401080772864	1.08584731766505	0.15059888048415	0.303984272249401	0.146697460542374	0.957826392590786	NA	NA	0.106787687450038	0.683324619088684	86.6497820960001
a10478	gain_cnaOV48_(SOX17)	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.35570219713121	2.35704219651811	-0.00133999938690144	1.42774087796156	0.821200093024965	0.00153174511856184	0.000938545227348683	0.00163175747090508	0.957939881800497	NA	NA	0.652603716087527	0.998861273532022	86.6497820960001
a10479	gain_cnaOV95_(MECOM)	263	FR-180204	ERK	9	23	2.99573227355399	NA	4.82154294826349	4.8079391751514	0.013603773112087	0.862753004992707	0.709450266930692	0.0180568111667722	0.0157678652329957	0.0191750905541854	0.95800684123658	NA	NA	0.766637346194145	0.967112836448732	86.6497820960001
a10480	loss_cnaOV70	235	QL-XII-47	BTK, BMX	3	29	2.32630161961136	NA	1.80156258882072	1.54084674189958	0.260715846921138	0.388153994359441	1.68690032562047	0.159676114263434	0.67168147361562	0.154553202083972	0.958007351944264	NA	NA	0.0806200494397637	0.509724414558681	86.6497820960001
a10481	loss_cnaOV39	265	Tubastatin A	HDAC6	9	22	2.99573227355399	NA	4.66899603559963	4.79198779433113	-0.122991758731498	1.16242776850182	1.26437466371323	0.0994201548765777	0.105805936561559	0.0972747732624555	0.958082083550802	NA	NA	0.427852460179606	0.797716563882441	86.6497820960001
a10482	gain_cnaOV72_(ASXL1)	156	AZD6482	PI3Kbeta	4	15	1.63315443905142	NA	2.18762318607243	2.12636996501751	0.0612532210549253	2.22546593639946	1.38048000407761	0.0391858536849613	0.0275237738098232	0.0443709585607888	0.958291534691235	NA	NA	0.948311099384906	0.960940646817912	86.6497820960001
a10483	gain_cnaOV18_(CCNE1)	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.77617729803734	8.74673233997213	0.0294449580652127	1.5707001182444	1.21806055413001	0.0236393688697361	0.0187463906847628	0.0241736406005229	0.958313118340614	NA	NA	0.532583831522477	0.977450557246405	86.6497820960001
a10484	gain_cnaOV19	1001	AICAR	AAPK1 (AMPK) agonist	3	28	7.60090245954208	NA	8.77617729803734	8.74673233997213	0.0294449580652127	1.5707001182444	1.21806055413001	0.0236393688697361	0.0187463906847628	0.0241736406005229	0.958313118340614	NA	NA	0.532583831522477	0.977450557246405	86.6497820960001
a10485	SMARCA4_mut	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.6538214739555	5.72140982411528	-0.0675883501597818	0.65397724277341	0.466729199426514	0.140375279042549	0.103349697419364	0.144812774180038	0.958358115805832	NA	NA	0.384678209358579	0.876155831927926	86.6497820960001
a10486	loss_cnaOV55	1192	GSK269962A	ROCK1, ROCK2	7	25	1.6094379124341	NA	2.59691540162034	2.39561829885833	0.20129710276201	2.0591324358082	1.27783934753569	0.137146279533505	0.0977582108180438	0.157529272478744	0.958551446812116	NA	NA	0.243014552934416	0.812616323634244	86.6497820960001
a10487	MLL2_mut	1066	AZD6482	PI3Kbeta	3	30	1.6094379124341	NA	1.53837178524902	2.46318783199055	-0.924816046741526	0.456856019514479	1.32707159306548	0.717588115665021	2.02430526738899	0.696884818855357	0.958558921859076	NA	NA	0.112118738150079	0.0388803117474492	86.6497820960001
a10488	loss_cnaOV85	172	Embelin	XIAP	6	13	3.46573590279973	NA	3.08173934214487	3.1054784614964	-0.0237391193515353	1.23747223009154	0.833678056507061	0.0244720821166969	0.0191835572340715	0.0284751639631698	0.958559879347662	NA	NA	0.67443701292762	0.967082428866209	86.6497820960001
a10489	TP53_mut	331	QL-X-138	MNK2, PRKDC (DNAPK), MTOR, BTK, JAK3	21	10	2.32630161961136	NA	2.29123605130537	2.29926538880693	-0.00802933750156631	1.38903511788019	1.49590658779164	0.00564229913511558	0.00578051440039895	0.00536753936849747	0.958590379595296	NA	NA	0.532584317067524	0.98876736361458	86.6497820960001
a10490	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1261	rTRAIL	TR10A (DR4),  TR10B (DR5)	3	30	-2.30258509299405	NA	-0.388491145282492	-0.32697420350913	-0.0615169417733623	2.58581282353171	1.30002192042674	0.0433647856670308	0.0237901758447242	0.0473199265387533	0.958685038780162	NA	NA	0.889641172329571	0.971076046699952	86.6497820960001
a10491	loss_cnaOV41	1050	ZM-447439	AURKB	3	19	1.38629436111989	0.693147180559945	2.63085261967584	2.41965353754706	0.211199082128773	2.70033352019702	1.4253824259357	0.132058151973459	0.0782122210271875	0.148170117917744	0.958831988366643	NA	NA	0.231806060693582	0.905764958717843	86.6497820960001
a10492	loss_cnaOV36	1033	Vismodegib	SMO	3	28	2.30258509299405	NA	4.98456023277696	4.90305579788801	0.0815044348889593	1.60414995444192	0.785408606536131	0.0940009248967664	0.050808488734655	0.103773289738212	0.959103935286138	NA	NA	0.15683211107462	0.938323564485512	86.6497820960001
a10493	loss_cnaOV84	1021	Axitinib	PDGFR, KIT, VEGFR	6	24	0.693147180559945	NA	2.6555766956891	2.4927052759607	0.162871419728402	0.707700109783082	1.10539900797687	0.155777960545637	0.23014186019884	0.147341745879158	0.95916582358014	NA	NA	0.198622185249176	0.664745079807979	86.6497820960001
a10494	gain_cnaOV18_(CCNE1)	192	LFM-A13	BTK	4	15	2.77258872223978	NA	4.71178579034012	4.72863178938748	-0.0168459990473542	0.810122265223232	0.673914726032487	0.0240698322160184	0.0207943908845811	0.0249972264985675	0.959225419314905	NA	NA	0.957402505336609	0.971274795688492	86.6497820960001
a10495	loss_cnaOV52, loss_cnaOV53	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	24	1.38629436111989	0.693147180559945	2.79251032825404	2.82994930952442	-0.0374389812703764	2.02633605493301	1.38058624594954	0.0238037167370451	0.0184761955842582	0.0271181763401001	0.959249304866503	NA	NA	0.969000665911388	0.960126559868736	86.6497820960001
a10496	loss_cnaOV34	1061	SB590885	BRAF	5	28	1.6094379124341	NA	3.84578876730731	3.94213822728281	-0.0963494599755004	1.43092427825689	1.27183041830716	0.0744897845874426	0.0673337236914244	0.075756530578773	0.959345765033138	NA	NA	0.575458055001089	0.893215817351589	86.6497820960001
a10497	loss_cnaOV39	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	5	14	1.63315443905142	NA	1.22645042480837	1.15955094345746	0.0668994813509134	2.20151459940878	1.36522425136976	0.0417658720748411	0.0303879344560692	0.0490025585787768	0.959948092287174	NA	NA	0.539125576001438	0.951599288359745	86.6497820960001
a10498	loss_cnaOV87, loss_cnaOV88	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.92458047034906	4.85338975424433	0.0711907161047325	0.787529593618329	0.611896113330118	0.11387926261091	0.0903975122733414	0.116344448924985	0.96000203912875	NA	NA	0.0510113361300743	0.89177668830289	86.6497820960001
a10499	loss_cnaOV85	140	Vinorelbine	Microtubules	6	13	-2.74887219562247	NA	-3.54703227608021	-3.41472120779774	-0.132311068282473	2.05731669188637	1.66809516116673	0.0738601682500955	0.0643124458204611	0.0793186572101373	0.960006193453669	NA	NA	0.68478068898176	0.893589259067708	86.6497820960001
a10500	MLL2_mut	1502	Bicalutamide	ANDR (androgen receptor)	3	29	2.30258509299405	NA	4.40049179854553	4.52813375098802	-0.127641952442488	0.366586065438205	0.616296638407805	0.21172183312035	0.348190955621592	0.207111226133327	0.960125133926249	NA	NA	0.617264913113957	0.62922380604357	86.6497820960001
a10501	loss_cnaOV84	303	PIK-93	PI4K, PI3K	6	26	2.99573227355399	NA	2.82681326721303	2.92344054574053	-0.0966272785275071	0.980473381465505	1.30575989542798	0.0768467109627162	0.0985516591823014	0.0740008012696974	0.960179806368836	NA	NA	0.234471150674922	0.843104886949255	86.6497820960001
a10502	loss_cnaOV44	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.2392990062544	3.22870637247354	0.0105926337808544	1.18290985802857	1.24519905263165	0.00853457482855767	0.00895472610103022	0.0085067795052265	0.960181223736213	NA	NA	0.603202494353162	0.989376989782355	86.6497820960001
a10503	gain_cnaOV95_(MECOM)	300	CX-5461	RNA Pol I	8	23	2.32630161961136	NA	3.56767818576963	3.52956359078676	0.0381145949828734	1.66556295868748	1.74133329462047	0.0221165859119892	0.0228839112830109	0.0218881675900997	0.960215913101738	NA	NA	0.70039388249507	0.956917543339757	86.6497820960001
a10504	SMAD4_mut	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.46002417373674	3.46514071817088	-0.00511654443413834	1.34555004156713	1.09406389311486	0.00454170893554342	0.00380256718522281	0.00467664134273844	0.960227365792168	NA	NA	0.775542473295418	0.995501035962938	86.6497820960001
a10505	loss_cnaOV42	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.20693193741238	4.29524441682378	-0.088312479411397	0.617662364782847	0.846143995200074	0.106987592266854	0.142978566360353	0.104370508935084	0.960314112632332	NA	NA	0.319972012550702	0.810664357041936	86.6497820960001
a10506	loss_cnaOV39	1004	Vinblastine	Microtubules	10	21	-2.30258509299405	NA	-3.07871797242066	-3.42779284004684	0.349074867626176	1.87787150744481	1.80879473016135	0.190698009887263	0.185888579832151	0.192987552321671	0.960373145127959	NA	NA	0.141950933920016	0.630635633624252	86.6497820960001
a10507	loss_cnaOV81_(RB1)	260	NG-25	MAP3K7 (TAK1)	4	28	2.32630161961136	NA	2.92882118391353	3.02386181184982	-0.0950406279362896	0.832071114659228	1.1153496496472	0.0871661471190756	0.114221760931111	0.0852115101003098	0.960474284246474	NA	NA	0.437392894168734	0.847045070324819	86.6497820960001
a10508	gain_cnaOV51_(MYC)	272	AR-42	HDAC	7	23	1.63315443905142	NA	0.170521292360948	0.333012356574001	-0.162491064213053	1.22402825028134	1.99660573017296	0.0874410589406286	0.132751073494999	0.0813836511422699	0.960515879142188	NA	NA	0.488980402503827	0.797228992267534	86.6497820960001
a10509	KRAS_mut	308	XL-880	MET	7	25	1.63315443905142	NA	0.345520199837719	0.227220296952227	0.118299902885492	0.835983063544359	1.01021440450648	0.120979004596815	0.141509927705868	0.117103757734761	0.960571696200268	NA	NA	0.371264263720321	0.758120585809125	86.6497820960001
a10510	gain_cnaOV18_(CCNE1)	254	AC220	FLT3	4	28	0.0237165266173161	NA	2.48821854086319	2.51404817131475	-0.0258296304515602	0.52277690995388	0.645767998634313	0.0407059077055756	0.049408514339011	0.0399983128711632	0.960611558884571	NA	NA	0.858986327011749	0.932560680369683	86.6497820960001
a10511	gain_cnaOV4_(KRAS)	219	AT-7519	CDK9	8	24	2.32630161961136	NA	1.52387367718288	1.48898571568704	0.0348879614958426	1.73299414754575	1.71430794673865	0.0202992034510859	0.0201316095298132	0.0203510469412538	0.960666217079923	NA	NA	0.319113303433051	0.961383226984357	86.6497820960001
a10512	PTEN_mut	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	0.820628771648964	1.8572535450689	-1.03662477341993	1.65026212974175	1.56270996110241	0.659433359501242	0.6281576452234	0.663350717166127	0.960800953622945	NA	NA	0.0424653626407478	0.305736056324579	86.6497820960001
a10513	loss_cnaOV57_(ZNRF3)	1061	SB590885	BRAF	4	29	1.6094379124341	NA	3.84309120596508	3.93918790953775	-0.0960967035726688	2.26673258576765	1.14106451362338	0.0742894157002279	0.0423943716060907	0.0842167138013256	0.960879360215977	NA	NA	0.575459294522173	0.938501848682618	86.6497820960001
a10514	loss_cnaOV38	229	LY317615	PRKCB (PKCbeta)	8	24	2.99573227355399	2.32630161961136	2.83747074919797	2.71953476880188	0.117935980396088	1.83404246632133	1.64767896268654	0.0696609576354019	0.0643038438649899	0.0715770384078908	0.960921997309155	NA	NA	0.324305974453602	0.8746561414043	86.6497820960001
a10515	loss_cnaOV84	274	PXD101, Belinostat	HDAC	6	24	2.99573227355399	NA	0.76826255637711	0.876386572600792	-0.108124016223683	1.79058631236398	2.15423938944568	0.0516366745851296	0.0603846994010217	0.05019127249897	0.96093365590004	NA	NA	0.419079452875689	0.901922345634592	86.6497820960001
a10516	loss_cnaOV34	1164	XMD8-92	MAP2K5 (ERK5)	5	18	2.30258509299405	NA	3.00797053733874	2.89874726493414	0.109223272404608	1.12570547036989	0.786055075530069	0.126835466330976	0.097026509401894	0.138951169968534	0.961026883355833	NA	NA	0.334256081751249	0.846484724943505	86.6497820960001
a10517	loss_cnaOV55	207	AS601245	JNK 	3	15	2.07944154167984	NA	1.90638660840618	2.01088734125487	-0.104500732848682	1.01051493559948	1.00084514696091	0.104286010706712	0.103413348152729	0.104412488950964	0.96111748422517	NA	NA	0.484682661254682	0.880844169048483	86.6497820960001
a10518	PTEN_mut	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.45335917201147	2.34693975084085	0.106419421170627	0.738490777211142	0.883129867406468	0.121729029072889	0.144103927164144	0.120502572835809	0.961219403362123	NA	NA	0.652606082651835	0.83271314075758	86.6497820960001
a10519	loss_cnaOV84	275	I-BET	BRD2, BRD3, BRD4	6	25	2.99573227355399	NA	3.90836632284181	3.92261542055157	-0.0142490977097647	0.783386754600596	1.30586595168559	0.011568659742804	0.0181890970533826	0.0109116082637519	0.961223617343522	NA	NA	0.700615444570386	0.973007104549867	86.6497820960001
a10520	loss_cnaOV84	186	Bexarotene	Retinioic acid X family agonist	4	14	2.07944154167984	NA	3.82246847688618	3.76747427242807	0.0549942044581129	0.718938466070512	1.04674250087814	0.0553511144545586	0.0764936180959876	0.0525384269884681	0.961256458329414	NA	NA	0.810209840046976	0.907233671216604	86.6497820960001
a10521	MLL2_mut	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.53387278228324	2.34376293421506	0.190109848068184	1.3962968839711	0.826385007029614	0.217022490830995	0.13615288428311	0.23004997241119	0.961279204388929	NA	NA	0.610166485053051	0.837022575938977	86.6497820960001
a10522	loss_cnaOV44	1006	Cytarabine	DNA synthesis	3	28	0.693147180559945	NA	-0.115429580250624	-0.110867841012313	-0.00456173923831114	1.43036294526352	1.25771145613564	0.00359086885944888	0.00318921799073222	0.00362701573246953	0.961293268267593	NA	NA	0.768604832780269	0.99618257895571	86.6497820960001
a10523	loss_cnaOV1	1018	ABT-888	PARP1, PARP2	3	28	1.6094379124341	NA	4.39861055686979	4.2889749635045	0.109635593365295	0.576977572236069	0.821904873874936	0.135788075117799	0.190017079763436	0.133392071090184	0.961317521760397	NA	NA	0.228057185794094	0.785232948143934	86.6497820960001
a10524	gain_cnaOV72_(ASXL1)	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.18536971455326	3.29300963941412	-0.10763992486086	1.35338004868247	0.994039594034933	0.102603388645665	0.0795341448735321	0.108285349503973	0.961490007442344	NA	NA	0.0938889706911733	0.872214435051174	86.6497820960001
a10525	loss_cnaOV52, loss_cnaOV53	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	3.44043443767167	3.27637959284914	0.164054844822533	1.0155822773539	0.979761326420764	0.165995901890608	0.161537719277632	0.167443682862901	0.96153386625653	NA	NA	0.194739325231752	0.763624695031636	86.6497820960001
a10526	loss_cnaOV44	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.54187868322556	3.54463067161124	-0.00275198838567992	1.03728378363879	0.901952322505384	0.00301885625719344	0.0026530718296067	0.00305114618257828	0.961578736813823	NA	NA	0.665253609017999	0.996820213111065	86.6497820960001
a10527	loss_cnaOV40	186	Bexarotene	Retinioic acid X family agonist	3	15	2.07944154167984	NA	3.82663306474122	3.77030763515427	0.0563254295869555	0.849112804273726	1.012557526017	0.0566883273125985	0.0663344485013773	0.0556268934255194	0.961635370776346	NA	NA	0.810210134373888	0.925164904516284	86.6497820960001
a10528	gain_cnaOV72_(ASXL1)	205	BMS-708163	g-secretase	5	27	2.32630161961136	0.940007258491471	5.0102920595685	5.07158097763723	-0.061288918068735	0.684103230780237	0.612166078654274	0.0984974853991271	0.0895901602435549	0.1001181218722	0.961759864982071	NA	NA	0.112735236824959	0.858704614990187	86.6497820960001
a10529	gain_cnaOV49	287	KIN001-244	PDPK1 (PDK1)	3	29	2.99573227355399	NA	3.49334673630806	3.54965121784409	-0.0563044815360318	0.546737189459418	0.932048005902169	0.0617751356247156	0.102982717513148	0.060409422239504	0.962301377938797	NA	NA	0.665254084664186	0.884644938457239	86.6497820960001
a10530	NF1_mut	1248	FK866	NAMPT	4	28	0	NA	-2.0177930688859	-1.66415270357321	-0.353640365312697	3.15210579758787	2.73313012186543	0.127306176295548	0.112191781628433	0.129390241058603	0.962434160841009	NA	NA	0.0458407521428389	0.84245255894948	86.6497820960001
a10531	loss_cnaOV21, loss_cnaOV22	1259	BMN-673	PARP1	3	30	2.30258509299405	NA	2.14705621804446	1.87574015215663	0.271316065887827	0.958339351040682	1.41342417450289	0.195392148988141	0.283110638828718	0.191956576647099	0.962475314612797	NA	NA	0.0352916500668738	0.6872775858015	86.6497820960001
a10532	loss_cnaOV21, loss_cnaOV22	268	YM155	BIRC5 (Survivin)	3	27	1.63315443905142	NA	-4.2289193789404	-4.14251744012756	-0.0864019388128376	0.864101514064949	2.44444069460313	0.0365055594733962	0.0999904957999453	0.0353463019183068	0.962478749565042	NA	NA	0.928528112545816	0.903410923866173	86.6497820960001
a10533	PIK3R1_mut	312	AV-951	VEGFR	5	27	-2.05572501506252	NA	0.434636199690521	0.677849146872765	-0.243212947182243	0.81136030267117	0.579660466633849	0.395074350095784	0.299759485867789	0.419578289674656	0.962551722687847	NA	NA	0.0156832527557416	0.551138246862125	86.6497820960001
a10534	loss_cnaOV81_(RB1)	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	1.32928139867653	1.44858415849409	-0.119302759817558	1.81515843869296	1.80379971716917	0.0660965147779679	0.0657258106369296	0.0661396931610504	0.962582839773248	NA	NA	0.616934976780144	0.908302220588365	86.6497820960001
a10535	gain_cnaOV95_(MECOM)	163	JQ1	BRD4	5	14	0.940007258491471	NA	0.129931000773411	0.0737182887083895	0.0562127120650218	2.06556033464384	1.83172950879847	0.0297523470347805	0.0272142677811028	0.0306883258663528	0.9628083152339	NA	NA	0.58621794305075	0.958757050036491	86.6497820960001
a10536	gain_cnaOV94	203	BMS-345541	IKBKB	7	25	2.77258872223978	NA	3.37820164893125	3.24762789177714	0.130573757154108	0.933705788562062	1.0751421271669	0.124547827333268	0.139844647804097	0.121447903355979	0.962865594707225	NA	NA	0.0938898692989277	0.757995007297658	86.6497820960001
a10537	loss_cnaOV21, loss_cnaOV22	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	5.93490786480077	5.94845389667485	-0.0135460318740845	0.342307082790489	0.726748278302411	0.0191254958683048	0.0395727478486779	0.0186392349022502	0.962935529467043	NA	NA	0.909250151826199	0.957254271309827	86.6497820960001
a10538	loss_cnaOV34	1022	AZD7762	CHEK1, CHEK2	5	26	0.693147180559945	NA	-0.718360172982468	-0.834103329960058	0.11574315697759	0.805855464139259	0.81325978448698	0.142498275196294	0.143627687753183	0.142320030063459	0.96300041100227	NA	NA	0.0806181620538862	0.779421842464608	86.6497820960001
a10539	loss_cnaOV40	286	KIN001-236	TIE2	7	25	2.32630161961136	NA	4.81927870827545	4.78829245576032	0.0309862525151399	0.817333221156442	0.627226511659194	0.0462771569260648	0.0379114071385689	0.0494020133702135	0.96302217110672	NA	NA	0.763542657665731	0.928217013513034	86.6497820960001
a10540	loss_cnaOV85	157	JNK-9L	JNK	6	13	1.63315443905142	NA	-0.12216983023028	0.0103482791484905	-0.132518109378771	1.2148274540412	0.924769984542333	0.13008669650074	0.109083894126644	0.1432984543117	0.963235874217684	NA	NA	0.195369753909646	0.818508232192989	86.6497820960001
a10541	loss_cnaOV54	1194	SB-505124	TGFR1 (ALK5)	10	22	2.30258509299405	NA	4.59446509134324	4.58569723917784	0.00876785216539488	0.698343271628468	1.04229431062296	0.00920756596392889	0.0125552182166073	0.00841206948558946	0.96324614082854	NA	NA	0.943498019879849	0.977892221150292	86.6497820960001
a10542	SMAD4_mut	1023	GW 441756	NTRK1	4	27	0.693147180559945	NA	2.33728888381031	2.29271748935639	0.0445713944539157	1.20014972161041	1.27475482166759	0.0351720022557463	0.0371381950529537	0.0349646800281241	0.963246832190615	NA	NA	0.845516301560442	0.948429519041109	86.6497820960001
a10543	gain_cnaOV72_(ASXL1)	134	Etoposide	TOP2	4	15	2.77258872223978	NA	2.49053648111924	2.22805061001381	0.262485871105432	1.50556326121568	1.91576503185135	0.141884448030753	0.174343966718134	0.137013603829992	0.963276916064569	NA	NA	0.414331797513986	0.78069095882903	86.6497820960001
a10544	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	229	LY317615	PRKCB (PKCbeta)	3	29	2.99573227355399	2.32630161961136	2.81966263868502	2.74171077685427	0.0779518618307469	1.1381156518432	1.7265133939524	0.0460257261272395	0.0684920391917136	0.0451498737882921	0.96335422346489	NA	NA	0.324308392209657	0.921712753100257	86.6497820960001
a10545	loss_cnaOV58	294	MPS-1-IN-1	MPS1	5	26	2.99573227355399	NA	4.24151121639121	4.29199118930521	-0.0504799729139958	0.61204770674762	0.855044955693515	0.0611292916362242	0.0824771865942328	0.0590377997997218	0.963355463582847	NA	NA	0.31997516851567	0.879246218467046	86.6497820960001
a10546	loss_cnaOV58	253	XMD14-99	EPHB3, CAMK1	5	27	2.32630161961136	NA	4.95213542811818	4.84301359790895	0.109121830209227	0.485691369038214	0.642831389094704	0.174827279554507	0.224673192001156	0.169751869713305	0.96350352554767	NA	NA	0.0510129413851443	0.675768405666503	86.6497820960001
a10547	loss_cnaOV54	344	THZ-2-49	CDK9	10	22	2.99573227355399	NA	2.75295430524622	2.51190820379527	0.241046101450953	2.32825525338331	2.36040580222067	0.102537605704265	0.103530788173108	0.102120618930938	0.963532065229396	NA	NA	0.388926822290726	0.790062054775429	86.6497820960001
a10548	PIK3CA_mut	1001	AICAR	AAPK1 (AMPK) agonist	7	24	7.60090245954208	NA	8.60566967049051	8.79155623832908	-0.185886567838576	1.10720120718479	1.27608524016574	0.149543382540232	0.167888696862261	0.145669397300162	0.963619579383605	NA	NA	0.532588653152969	0.713194958533291	86.6497820960001
a10549	gain_cnaOV26	1072	BMS-708163	g-secretase	3	30	1.6094379124341	NA	3.8130223833961	3.84421151329195	-0.0311891298958566	0.603212035839574	0.887167918883247	0.0357819522318462	0.0517050855134984	0.0351558360396046	0.963829777984284	NA	NA	0.924206712163282	0.940476206219313	86.6497820960001
a10550	gain_cnaOV4_(KRAS)	186	Bexarotene	Retinioic acid X family agonist	6	12	2.07944154167984	NA	3.75365862668621	3.79271349678504	-0.0390548700988291	1.14117812104536	0.91880338442025	0.0393042187450919	0.0342232902809715	0.0425062323028687	0.96386830846102	NA	NA	0.810211809916457	0.943636550506815	86.6497820960001
a10551	SMAD4_mut	205	BMS-708163	g-secretase	3	29	2.32630161961136	0.940007258491471	5.14327913933587	5.05359687158759	0.0896822677482749	1.06062733130998	0.578160216858387	0.144165829331082	0.084555870946215	0.155116635723557	0.963988256384021	NA	NA	0.112736809240843	0.89783033220037	86.6497820960001
a10552	gain_cnaOV72_(ASXL1)	152	CP466722	ATM	5	27	2.77258872223978	NA	2.61179024493819	2.65342158132342	-0.041631336385231	0.871601109090034	0.812302616707675	0.050741659095675	0.047764207676026	0.0512510184369047	0.964013661207723	NA	NA	0.558390042282698	0.924631882558371	86.6497820960001
a10553	loss_cnaOV35	203	BMS-345541	IKBKB	5	27	2.77258872223978	NA	3.41253565943122	3.25094187184412	0.1615937875871	0.885335169532229	1.07096248859203	0.154175863987077	0.182522724893532	0.15088650565114	0.964092877060641	NA	NA	0.0938906433642109	0.729011184992131	86.6497820960001
a10554	loss_cnaOV40	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	7	25	0.246860077931526	2.32630161961136	0.999492518457132	1.00548961259473	-0.00599709413760008	1.61962412603284	1.54731746748554	0.00383925434095617	0.00370276908154583	0.00387580070904623	0.964232715495328	NA	NA	0.792288533047253	0.993208790338	86.6497820960001
a10555	loss_cnaOV85	136	Mitomycin C	DNA crosslinker	6	13	2.77258872223978	NA	-0.51813652934923	-0.572560500390311	0.0544239710410809	1.1588485249488	1.63129997451672	0.0360951915107985	0.0469638351082038	0.0333623318158907	0.964244177304691	NA	NA	0.910231182182616	0.934953453580616	86.6497820960001
a10556	loss_cnaOV87, loss_cnaOV88	283	GSK2126458	PI3K, MTOR	3	29	-2.05572501506252	0.0237165266173161	-2.64026195364113	-2.74169203626392	0.101430082622782	0.95360965625823	1.82793102477303	0.0568863117358581	0.106364361934812	0.0554890098412635	0.964288108601906	NA	NA	0.698079858525465	0.883422253186047	86.6497820960001
a10557	loss_cnaOV70	1038	NU-7441	PRKDC (DNAPK)	3	30	0.693147180559945	NA	2.57741169665742	2.53300788701486	0.0444038096425641	1.15855377385961	1.03520480247565	0.0425485706725196	0.0383269302163135	0.0428937438624455	0.96438387656782	NA	NA	0.397975522672937	0.954129146832821	86.6497820960001
a10558	gain_cnaOV26	176	IPA-3	PAK1, PAK2, PAK3	3	16	3.46573590279973	NA	4.99019248403417	4.71764430329485	0.272548180739318	1.65083002899369	1.57921521444276	0.171650574822986	0.165097663570766	0.172584571277379	0.964397584966086	NA	NA	0.125619696767293	0.810275439876513	86.6497820960001
a10559	gain_cnaOV4_(KRAS)	173	FH535	unknown 	6	12	3.46573590279973	NA	2.61176012540442	2.43935951909092	0.172400606313507	1.01878895744132	1.61871449394397	0.11824452781965	0.169221117930537	0.106504641157228	0.964439541867561	NA	NA	0.125411671972684	0.786664462094997	86.6497820960001
a10560	loss_cnaOV21, loss_cnaOV22	312	AV-951	VEGFR	3	29	-2.05572501506252	NA	0.723837861234578	0.631158426907363	0.0926794343272158	0.0819633809989921	0.643154779433524	0.14907256589754	1.13074196302804	0.14410129146338	0.964470713762949	NA	NA	0.0156836165334662	0.476647937833939	86.6497820960001
a10561	NF1_mut	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.848065972241574	-0.725540894924474	-0.1225250773171	1.06815495978812	0.914207714606806	0.13171623818421	0.114707211902479	0.134023237125927	0.964481943588837	NA	NA	0.0431175350243449	0.838658981078581	86.6497820960001
a10562	gain_cnaOV95_(MECOM)	256	JW-7-24-1	LCK	9	23	2.32630161961136	NA	1.95877118957492	1.93174234318511	0.0270288463898103	1.05942540079416	1.44496443845432	0.0199778699684172	0.0255127415007692	0.0187055443514741	0.964686150324812	NA	NA	0.840047128855915	0.954145815136921	86.6497820960001
a10563	loss_cnaOV34	1143	HG-5-88-01	EGFR, ADCK4	4	18	2.30258509299405	NA	3.49638391164169	3.65125000579751	-0.154866094155815	0.910515143628444	0.91485492239864	0.169399695476387	0.170086236609604	0.169279401973129	0.964779474886832	NA	NA	0.0620883115610199	0.772352362048075	86.6497820960001
a10564	loss_cnaOV70	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.5397589414135	4.38494264570455	0.154816295708954	0.397124653027446	0.797945682762938	0.199256497135451	0.389843074532706	0.194018589301583	0.964823238624383	NA	NA	0.0443649320076891	0.602443364447896	86.6497820960001
a10565	loss_cnaOV33_(ZFHX3)	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-2.11279828650957	-1.97283787273398	-0.139960413775594	2.20933774892218	2.0313349334004	0.0682987971838488	0.0633494873492626	0.068900707349774	0.964929713265367	NA	NA	0.281188454368543	0.910730982390251	86.6497820960001
a10566	loss_cnaOV34	1032	Afatinib	ERBB2, EGFR	5	26	-0.693147180559945	NA	0.41557427630738	0.345849974672863	0.0697243016345165	1.6930729164154	1.68902333022575	0.0412671786288877	0.0411821020574458	0.0412808398716418	0.964980748586567	NA	NA	0.838256684841778	0.935677498457115	86.6497820960001
a10567	ARID1A_mut	222	BX-912	PDPK1 (PDK1)	8	24	2.32630161961136	NA	3.17773163155208	3.48731237910619	-0.309580747554117	0.750094339995689	1.33480589088103	0.253002954767325	0.412722415097675	0.231929413609181	0.965163784897601	NA	NA	0.329750782746426	0.424214915316449	86.6497820960001
a10568	loss_cnaOV85	1373	Dabrafenib	BRAF	7	25	2.30258509299405	NA	3.66122537559524	3.64211476329257	0.0191106123026747	3.31611097445717	1.57255740128616	0.00934991471425932	0.00576295921634621	0.0121525689854276	0.965228641275165	NA	NA	0.74893880443885	0.988626810641773	86.6497820960001
a10569	loss_cnaOV35	1030	KU-55933	ATM	5	28	2.30258509299405	NA	4.21814024510938	4.13900447684879	0.0791357682605884	1.37166662885562	0.978715590736788	0.0762524115812747	0.0576931497754753	0.0808567565588836	0.965740390915511	NA	NA	0.532173834506626	0.906750765469455	86.6497820960001
a10570	loss_cnaOV39	1158	XMD11-85h	BRSK2, FLT4, MARK4, PRKCD, RET, SPRK1	7	16	2.30258509299405	NA	3.86010481813	3.85074126907436	0.00936354905564363	1.22658543848353	0.718237829073096	0.0104796710322097	0.00763383353647186	0.0130368363745579	0.965803090403589	NA	NA	0.940411751815938	0.985442633848743	86.6497820960001
a10571	gain_cnaOV94	1021	Axitinib	PDGFR, KIT, VEGFR	6	24	0.693147180559945	NA	2.65246153744561	2.49348406552157	0.158977471924047	1.20643640045303	1.00729144316408	0.152038663952464	0.131774432422918	0.157826687601624	0.965849465525881	NA	NA	0.198628658946593	0.77463689719283	86.6497820960001
a10572	gain_cnaOV19	175	PAC-1	CASP3 agonist	3	15	0.940007258491471	NA	2.18811264908259	2.13005768138438	0.0580549676982147	1.31238147629157	1.38848870209189	0.0420930666964395	0.0442363510511152	0.0418116241138652	0.96587293748001	NA	NA	0.893554038635151	0.949176830247896	86.6497820960001
a10573	loss_cnaOV42	272	AR-42	HDAC	4	26	1.63315443905142	NA	0.238009124551592	0.303880644212396	-0.065871519660804	1.52260971275835	1.89591839005209	0.0354241430038022	0.0432622484336261	0.0347438581778797	0.965950238147544	NA	NA	0.488985509380715	0.941316216648015	86.6497820960001
a10574	gain_cnaOV19	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	2.8984398836985	2.77752440034665	0.120915483351844	0.395799251564442	1.27744810019981	0.0976419315754672	0.305496998475646	0.0946539302324152	0.966084548394113	NA	NA	0.0967787825578147	0.723097285072777	86.6497820960001
a10575	gain_cnaOV94	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	3	16	1.63315443905142	NA	1.2208355261044	1.16896617213332	0.0518693539710757	2.60515891832705	1.41545131646755	0.0323788481822392	0.0199102456307674	0.0366450992468767	0.966115541389377	NA	NA	0.539134848192284	0.975991211979657	86.6497820960001
a10576	gain_cnaOV48_(SOX17)	253	XMD14-99	EPHB3, CAMK1	3	29	2.32630161961136	NA	4.92711208607159	4.85312786296269	0.0739842231089005	0.384228308816789	0.638852549828293	0.118353423525824	0.1925527646225	0.115807979679796	0.966164126992341	NA	NA	0.0510140626303838	0.786284239321021	86.6497820960001
a10577	loss_cnaOV102	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.44160669937498	4.405792539985	0.0358141593899726	0.69945405619055	0.632437949597368	0.0562121365925754	0.0512030190875265	0.0566287323725167	0.966165778966622	NA	NA	0.274103691443912	0.938845674737959	86.6497820960001
a10578	loss_cnaOV84	265	Tubastatin A	HDAC6	6	25	2.99573227355399	NA	4.70605265055994	4.76833519569288	-0.0622825451329367	1.49071212793762	1.17877319549968	0.0503018803692028	0.0417803974125466	0.0528367504204533	0.96639025286761	NA	NA	0.427860657052667	0.926812738951358	86.6497820960001
a10579	loss_cnaOV40	1001	AICAR	AAPK1 (AMPK) agonist	7	24	7.60090245954208	NA	8.82948309674795	8.72627732233733	0.103205774410624	1.21854100247004	1.25158857242667	0.0829079827173775	0.0846961851931292	0.0824598248053037	0.966451401115023	NA	NA	0.532590957253717	0.848564230486236	86.6497820960001
a10580	loss_cnaOV39	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.52539750742388	2.48030278460511	0.0450947228187739	1.35369594979158	0.48627900741549	0.0576433300719055	0.0333122979541433	0.0927342577637609	0.966495325546811	NA	NA	0.752027296821336	0.94515231583448	86.6497820960001
a10581	loss_cnaOV33_(ZFHX3)	1375	Temozolomide	DNA akylating agent	4	29	3.40119738166216	NA	5.96736258762523	5.94444448772921	0.0229180998960237	1.07057706991386	0.657683308927012	0.032359217606708	0.0214072396468081	0.0348467105443405	0.966637433281413	NA	NA	0.909250779600094	0.969090583940267	86.6497820960001
a10582	loss_cnaOV20	1031	Elesclomol	HSP70	4	27	-1.6094379124341	NA	-4.05094964419746	-4.06108008274183	0.0101304385443655	1.2411241925838	1.56807773909447	0.00658897764478327	0.00816230849813322	0.0064604185696913	0.967066727011079	NA	NA	0.864962887232656	0.98890756158985	86.6497820960001
a10583	MLL2_mut	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	3.12161451967194	4.06049610207603	-0.938881582404096	2.05452680398754	1.04284206810553	0.822307231631521	0.456981909694175	0.900310421989122	0.967072034014932	NA	NA	0.0847744066206505	0.512880054812835	86.6497820960001
a10584	ARID1A_mut	277	ABT-869	VEGFR and PDGFR family	8	24	0.0237165266173161	NA	2.54965928793247	2.77149472588572	-0.221835437953249	0.374161242751081	0.611966493679302	0.392285259686645	0.592887270531196	0.362496052062452	0.967099927937659	NA	NA	0.137986302304228	0.236818508704046	86.6497820960001
a10585	gain_cnaOV4_(KRAS)	151	QS11	ARFGAP	6	13	2.32630161961136	NA	3.62440972089619	3.83248859420892	-0.20807887331273	0.887936545865411	1.65928995338	0.14107910194026	0.234339800835576	0.125402358333376	0.967112083226336	NA	NA	0.0674401602798656	0.726981323766672	86.6497820960001
a10586	loss_cnaOV16, loss_cnaOV17	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	0	NA	-2.1240224270131	-1.9599761812313	-0.164046245781798	2.205223514652	2.01725460688438	0.0800718136390811	0.0743898496872712	0.081321537312122	0.967145637727845	NA	NA	0.281190346959806	0.871856406324483	86.6497820960001
a10587	loss_cnaOV58	1006	Cytarabine	DNA synthesis	5	26	0.693147180559945	NA	-0.102598637397631	-0.112984427004172	0.0103857896065414	1.18941724479035	1.28284458480546	0.0081754270221091	0.00873183035812801	0.00809590633936092	0.967251310489195	NA	NA	0.768607564988937	0.986495527674287	86.6497820960001
a10588	loss_cnaOV55	196	Phenformin	AAPK1 (AMPK) agonist	7	24	8.29404964010203	NA	8.72196460798807	8.76787560176963	-0.0459109937815594	2.17650575918773	1.58397700273562	0.0266403106675917	0.0210938995165781	0.0289846340586185	0.967276201417402	NA	NA	0.922301964355819	0.959857226047187	86.6497820960001
a10589	loss_cnaOV82	1026	17-AAG	HSP90	3	30	0	NA	-0.165218796325334	-0.56739349448652	0.402174698161186	0.842062319363241	2.3806746720378	0.173912575687841	0.477606809986827	0.168933077200731	0.967295453712178	NA	NA	0.0627855427570521	0.559372877086688	86.6497820960001
a10590	ARID1A_mut	345	KIN001-270	CDK9	8	24	2.99573227355399	NA	5.04580680388583	5.23913020202388	-0.193323398138052	0.884261351216242	0.735652896785275	0.250131121327777	0.218626990620079	0.262791595034635	0.967366855360949	NA	NA	0.336611888392066	0.589008622651282	86.6497820960001
a10591	loss_cnaOV38	1264	SGC0946	Q8TEK3 (DOT1L)	8	25	-0.693147180559945	NA	2.1916434383691	2.0908861437871	0.100757294582007	0.649053308040244	0.533750137475842	0.179328610008903	0.15523731769619	0.188772400244238	0.96744549179544	NA	NA	0.043510374069167	0.698740950119375	86.6497820960001
a10592	loss_cnaOV44	1022	AZD7762	CHEK1, CHEK2	3	28	0.693147180559945	NA	-0.686156297608358	-0.829286376823171	0.143130079214813	1.18015129806386	0.778116258190349	0.176212866879232	0.121281126792497	0.183944336991091	0.967519902458334	NA	NA	0.0806207373709276	0.854832392790743	86.6497820960001
a10593	NF1_mut	1018	ABT-888	PARP1, PARP2	4	27	1.6094379124341	NA	4.2719869553057	4.30367343805602	-0.0316864827503132	1.076082447572	0.771119666031104	0.0392148376368773	0.0294461477573661	0.0410915246311913	0.967792778706971	NA	NA	0.228063132559663	0.957840232100438	86.6497820960001
a10594	TP53_mut	136	Mitomycin C	DNA crosslinker	12	7	2.77258872223978	NA	-0.563552308344142	-0.541353997291388	-0.0221983110527532	1.61200445095074	1.2957728757419	0.0147205143192791	0.0137706264022168	0.0171313286983596	0.967852662187	NA	NA	0.910232292323885	0.974219833662445	86.6497820960001
a10595	gain_cnaOV94	274	PXD101, Belinostat	HDAC	6	24	2.99573227355399	NA	0.700433238124279	0.893343902164	-0.192910664039721	1.18323573765047	2.24233416598755	0.0921741493617385	0.163036542847143	0.0860311843639777	0.968005056637423	NA	NA	0.419086303824772	0.775787382792026	86.6497820960001
a10596	loss_cnaOV57_(ZNRF3)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	2.75470601330803	2.87934751668641	-0.124641503378384	0.936780729944136	0.793318987688957	0.154104598450447	0.13305301805879	0.157113979764282	0.968079749070914	NA	NA	0.0201959253356486	0.813582619226619	86.6497820960001
a10597	loss_cnaOV84	175	PAC-1	CASP3 agonist	4	14	0.940007258491471	NA	2.1809580652564	2.12795506478484	0.0530030004715507	1.75933409412385	1.27548539851306	0.0384303090153173	0.0301267397980747	0.0415551605164125	0.968087375888013	NA	NA	0.893554876737424	0.957924476182075	86.6497820960001
a10598	gain_cnaOV95_(MECOM)	277	ABT-869	VEGFR and PDGFR family	9	23	0.0237165266173161	NA	2.72877191108761	2.71105219673603	0.0177197143515788	0.63688421657633	0.549454598167981	0.0308666794492763	0.027822505080804	0.0322496424830382	0.96824298488073	NA	NA	0.137987075216925	0.942568494759099	86.6497820960001
a10599	SMARCA4_mut	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-1.65067499131639	-1.282922234052	-0.367752757264391	3.55341741351068	1.70331144986867	0.195192879542575	0.103492698568464	0.215904588261146	0.968373719334474	NA	NA	0.0758682626720096	0.875032747012132	86.6497820960001
a10600	PTEN_mut	1371	PLX4720 (rescreen)	BRAF	4	29	2.30258509299405	NA	4.22610339362204	4.56995538785823	-0.343851994236188	0.984819622442483	0.989957390692044	0.347514324946166	0.349152257327478	0.347340196122798	0.968623026963742	NA	NA	0.328413576186275	0.549668301169593	86.6497820960001
a10601	loss_cnaOV35	136	Mitomycin C	DNA crosslinker	3	16	2.77258872223978	NA	-0.573884659757315	-0.551903231368592	-0.0219814283887234	1.81425317627238	1.46233226076895	0.0145765108836292	0.0121159652226086	0.0150317605502081	0.968633641288831	NA	NA	0.910232517022262	0.985657618224288	86.6497820960001
a10602	TP53_mut	303	PIK-93	PI4K, PI3K	22	10	2.99573227355399	NA	2.90865210525569	2.89799874769067	0.0106533575650194	1.19414894501677	1.39565890016176	0.00846851630111113	0.00892129713757755	0.00763321006571493	0.968721885494916	NA	NA	0.234478800347761	0.983589262090026	86.6497820960001
a10603	loss_cnaOV85	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	1.39206532697448	1.31713105798418	0.0749342689903014	1.29144832862071	1.53515421167448	0.0503047522667	0.0580234356494408	0.048812209496899	0.968858126256558	NA	NA	0.858386075713117	0.92602897416582	86.6497820960001
a10604	TP53_mut	201	Epothilone B	Microtubules	12	7	-3.44201937618241	NA	-4.67230991822846	-4.62287510502394	-0.0494348132045284	2.215471723438	1.82988112162433	0.0236810123466572	0.0223134480488041	0.02701531406622	0.968895197647698	NA	NA	0.355153696975291	0.958851321475486	86.6497820960001
a10605	loss_cnaOV41	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.35332626793053	2.40097912669613	-0.0476528587656047	1.05740729752231	0.932616854579471	0.0501501898186819	0.0450657555298357	0.0510958584241885	0.968998327937737	NA	NA	0.736407971313497	0.928451344140312	86.6497820960001
a10606	loss_cnaOV38	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	8	23	3.68887945411394	NA	3.47520565493209	3.49462137065058	-0.0194157157184951	0.892719069158416	1.18739182870409	0.017283556700347	0.0217489649199481	0.0163515658851091	0.969052709043427	NA	NA	0.728505975225473	0.961985044529202	86.6497820960001
a10607	loss_cnaOV56	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.45812509769554	2.26675996296526	0.191365134730277	1.30533714837074	1.8337195972856	0.106060251930489	0.146602075156698	0.104358995243084	0.969132412278971	NA	NA	0.112639860212475	0.832102578754285	86.6497820960001
a10608	loss_cnaOV35	1142	HG-5-113-01	LOK, LTK, TRCB, ABL(T315I)	5	18	2.30258509299405	NA	1.61349097287508	1.54915256121212	0.0643384116629659	1.85420421702398	0.802039237778233	0.0593387664690306	0.0346986653747503	0.0802185337480406	0.969206686466261	NA	NA	0.458193302576501	0.942998957704118	86.6497820960001
a10609	SMARCA4_mut	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.3526948256642	3.32235020306514	0.0303446225990562	1.86776734521763	1.18320830196539	0.0244585879015288	0.0162464681036173	0.0256460528113703	0.969291705867013	NA	NA	0.993651789085731	0.980331697353344	86.6497820960001
a10610	loss_cnaOV36	1020	Lenalidomide	TNFA	3	28	1.6094379124341	NA	4.5374746914693	4.38518738677	0.1522873046993	1.19455829701086	0.736733251782035	0.195989776566682	0.127484196527174	0.206706164450895	0.969338875206798	NA	NA	0.0443666123085818	0.847337086763633	86.6497820960001
a10611	MLL2_mut	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	1.12512593374523	2.40005987936029	-1.27493394561506	0.642672399490407	1.81717728094723	0.722282551491276	1.98380068387252	0.701601301635515	0.9694341177937	NA	NA	0.112640030481652	0.0415861848769793	86.6497820960001
a10612	gain_cnaOV51_(MYC)	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	2.72116307807204	2.70461836349783	0.0165447145742181	1.18118461500328	1.39823826289244	0.0122525363437385	0.0140068828903365	0.0118325431461111	0.969493083373298	NA	NA	0.941801049347579	0.980200854221934	86.6497820960001
a10613	loss_cnaOV16, loss_cnaOV17	1529	MLN4924	NEDD8-activating enzyme	3	14	0	NA	1.39687511086463	1.32145283779274	0.0754222730718948	1.58165083824446	1.47501710028034	0.0506299841012309	0.0476857921155399	0.0511331516479097	0.969504435675035	NA	NA	0.858386400171845	0.944643543766749	86.6497820960001
a10614	loss_cnaOV85	266	Zibotentan, ZD4054	Endothelin A Receptor	7	25	2.99573227355399	NA	5.7375165851025	5.70878932901969	0.0287272560828171	0.690651888722058	0.413354720299737	0.0596301918383908	0.0415944074749037	0.0694978300041815	0.969621711249041	NA	NA	0.384688709669979	0.919290313978955	86.6497820960001
a10615	loss_cnaOV43_(NF1)	306	TG101348	JAK2	5	27	2.32630161961136	NA	2.84831822514492	2.81956609844731	0.0287521266976043	1.67286296624323	1.36313907488501	0.0204150850751316	0.0171873771359607	0.0210925849220703	0.969633489872403	NA	NA	0.629611622068949	0.97246408184795	86.6497820960001
a10616	SMAD4_mut	299	OSI-027	MTORC1/2	3	29	2.99573227355399	NA	1.45359942921104	1.53906503029616	-0.085465601085116	1.78766115852529	1.94456020789379	0.0441797716909973	0.0478086133255924	0.0439511210494666	0.969669267891215	NA	NA	0.783933224473088	0.943485858613166	86.6497820960001
a10617	loss_cnaOV87, loss_cnaOV88	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	0.774784401026086	0.863648143614941	-0.0888637425888554	1.69279092829803	2.12197203297747	0.042432553000927	0.0524954033621865	0.041877904707427	0.969730820296781	NA	NA	0.419087768331328	0.938862343853879	86.6497820960001
a10618	loss_cnaOV40	211	TL-2-105	CRAF	7	25	2.32630161961136	1.63315443905142	4.44846921597253	4.39814076983529	0.0503284461372404	0.860535175695121	0.567316770567133	0.0790266825051895	0.0584850539044917	0.0887131295042244	0.969731791122146	NA	NA	0.274106654541977	0.887680098081858	86.6497820960001
a10619	SMARCA4_mut	1161	ZG-10	IRAK1	3	20	2.30258509299405	NA	1.329440000959	1.61484625942062	-0.285406258461622	0.440871127224749	1.32542356002241	0.225075016489148	0.64736890405646	0.215332115008425	0.969833964398716	NA	NA	0.167603647904615	0.483053243969649	86.6497820960001
a10620	gain_cnaOV48_(SOX17)	258	STF-62247	stimulates autophagy	3	28	2.32630161961136	NA	4.56601762550672	4.48128994029562	0.0847276852111092	0.34997585658853	0.70011981558538	0.124276072427159	0.242095800656113	0.121018836097743	0.970015460525628	NA	NA	0.0548903581611698	0.743314256873469	86.6497820960001
a10621	gain_cnaOV51_(MYC)	1378	Bleomycin (50 uM)	DNA damage	8	24	3.91202300542815	NA	2.22122897160148	1.98212760604353	0.23910136555795	1.72502223646834	2.07808964234028	0.1194738395504	0.138607700528815	0.115058253833882	0.970117999568019	NA	NA	0.134803543751455	0.752196036810857	86.6497820960001
a10622	gain_cnaOV51_(MYC)	341	EX-527	SIRT1	7	24	2.99573227355399	NA	5.84273278801089	5.75306588039617	0.0896669076147285	0.646352043821289	0.545782093335332	0.157849715232388	0.138727661607767	0.164290673346875	0.970191094594931	NA	NA	0.112903869757694	0.746361686625639	86.6497820960001
a10623	gain_cnaOV18_(CCNE1)	1039	SL 0101-1	RSK, AURKB, PIM3	4	29	2.30258509299405	NA	4.91884181434835	4.9402590813999	-0.0214172670515556	1.01939629116607	0.801946852742886	0.0259446772110687	0.0210097557124292	0.0267065915631471	0.970205585091811	NA	NA	0.946305636590334	0.970002528022186	86.6497820960001
a10624	loss_cnaOV20	1062	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.38629436111989	0.693147180559945	2.8395306028327	2.81620440602532	0.0233261968073797	2.22393953002534	1.45181831569789	0.0148301397793553	0.0104886830295758	0.0160668842341796	0.970213828418958	NA	NA	0.969001304629609	0.982904261643715	86.6497820960001
a10625	loss_cnaOV16, loss_cnaOV17	153	Midostaurin	KIT	3	16	-0.669430653942629	NA	0.164017759500395	0.110213916296842	0.0538038432035524	2.56061901543174	1.08912636007952	0.0399036815589406	0.0210120454777927	0.0494009190996204	0.970507092782324	NA	NA	0.871356647838232	0.974512354215442	86.6532679574012
a10626	loss_cnaOV52, loss_cnaOV53	1133	JNJ-26854165	MDM2	9	24	2.30258509299405	NA	3.15807765142158	3.03402365785018	0.124053993571406	0.659826527502385	1.00016959623167	0.134197461856058	0.188010012330033	0.124032958049119	0.970552157134212	NA	NA	0.241678416418996	0.683319101105365	86.6532679574012
a10627	gain_cnaOV94	310	YM201636	FYV1	7	25	1.63315443905142	NA	2.34073247910564	2.36144811746718	-0.020715638361537	0.302429502494023	0.966266721253018	0.0236811275751108	0.068497412424062	0.0214388407526586	0.970678325234933	NA	NA	0.652611830027767	0.927115965567435	86.6532679574012
a10628	loss_cnaOV43_(NF1)	295	NVP-BHG712	EPHB4	5	27	2.32630161961136	NA	3.10032246730544	3.27905703433841	-0.178734567032973	0.918822273649215	1.11833164758336	0.163401774496806	0.194525722937806	0.159822506516029	0.970722318354545	NA	NA	0.0639502343494784	0.712444367549167	86.6532679574012
a10629	loss_cnaOV84	256	JW-7-24-1	LCK	6	26	2.32630161961136	NA	1.93978763514056	1.93924187648417	0.000545758656388173	0.572498166023104	1.45985341814222	0.000403370026697115	0.00095329328332931	0.000373844832368647	0.970967474370132	NA	NA	0.840048886795948	0.998835364554979	86.6532679574012
a10630	SMARCA4_mut	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.60951371325503	2.7270553994811	-0.11754168622607	0.766271432620124	0.556677156268404	0.205119479035916	0.153394321153482	0.211148750945687	0.971008334232857	NA	NA	0.137988831845831	0.817860619623075	86.6532679574012
a10631	PTEN_mut	1061	SB590885	BRAF	4	29	1.6094379124341	NA	4.16037848375296	3.89542414708425	0.264954336668713	0.73990829887027	1.33649757813355	0.205252515552406	0.358090775672146	0.1982452800541	0.971080855620478	NA	NA	0.575466323865755	0.573148154769694	86.6532679574012
a10632	RB1_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.37699172244992	1.33592340131962	0.0410683211303	0.544102221249841	1.40520214339927	0.0301222190928094	0.0754790543511534	0.0292259169424218	0.971208038932301	NA	NA	0.583305085330092	0.923910133767859	86.6532679574012
a10633	loss_cnaOV57_(ZNRF3)	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	8.77484324967897	8.75494050739525	0.0199027422837119	1.84774113222928	1.70854501050485	0.0115480908649667	0.0107713910442095	0.0116489423230535	0.971408917589686	NA	NA	0.922302525239085	0.984827786968013	86.6532679574012
a10634	loss_cnaOV54	202	GSK-1904529A	IGF1R	6	13	0.0237165266173161	NA	2.52210493334204	2.47835360934913	0.0437513239929141	0.312815526580181	0.908955968903851	0.0559270850817778	0.139863019176894	0.0481336010650502	0.971455637444783	NA	NA	0.752031026985873	0.87885913841511	86.6532679574012
a10635	SMAD4_mut	328	SNX-2112	HSP90	3	29	0.940007258491471	NA	0.660305412236932	0.699857031819881	-0.0395516195829496	2.3258525320851	2.32997512737176	0.0169771261731867	0.0170052138032552	0.0169751252355918	0.971473593453644	NA	NA	0.946179688086241	0.979768030991773	86.6532679574012
a10636	KRAS_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	7	25	0.246860077931526	2.32630161961136	1.05873714175819	0.988901118070437	0.0698360236877482	1.70753738205872	1.52314241895562	0.044716115918923	0.0408986792450479	0.0458499630885687	0.971701516108217	NA	NA	0.792291208499505	0.924225204326097	86.6532679574012
a10637	loss_cnaOV85	134	Etoposide	TOP2	6	13	2.77258872223978	NA	2.18205300019468	2.33004515950123	-0.147992159306555	2.61255113317753	1.41959170740426	0.0799082519149772	0.0566466077647858	0.10424980544382	0.971799928328132	NA	NA	0.414344616667247	0.900424658082693	86.6532679574012
a10638	loss_cnaOV38	235	QL-XII-47	BTK, BMX	8	24	2.32630161961136	NA	1.73911541794037	1.50734666408446	0.231768753855906	1.39420329481722	1.69699124393869	0.142069565292979	0.16623741653565	0.136576281512198	0.971806833952377	NA	NA	0.0806277293658613	0.706027734764863	86.6532679574012
a10639	loss_cnaOV55	192	LFM-A13	BTK	4	15	2.77258872223978	NA	4.71684971548946	4.72728140934765	-0.0104316938581883	0.235926952308258	0.763484353550201	0.0149044761539103	0.0442157784692546	0.0136632713030476	0.971825890148489	NA	NA	0.957404380011581	0.964338312283716	86.6532679574012
a10640	loss_cnaOV54	279	BIX02189	MAP2K5 (MEK5)	10	22	2.99573227355399	NA	4.39226423082617	4.44887338071879	-0.05660914989262	0.744391071050149	0.74301671281612	0.0761459776708266	0.0760475939250033	0.0761882591820374	0.971887380396031	NA	NA	0.526954534838102	0.844165852780541	86.6532679574012
a10641	loss_cnaOV85	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	6	13	1.63315443905142	NA	1.27687251497843	1.13113309558275	0.145739419395683	2.076456632486	1.35362115763233	0.0910601039070262	0.0701865943721634	0.107666327889409	0.97191912489658	NA	NA	0.53914215744219	0.87950386510775	86.6532679574012
a10642	loss_cnaOV21, loss_cnaOV22	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.55169475906695	3.55600253064348	-0.00430777157653273	0.947151267923938	0.969245682981743	0.00445115017935669	0.00454813473034242	0.00444445784197923	0.972022411600744	NA	NA	0.730111049683356	0.994594780694044	86.6532679574012
a10643	gain_cnaOV4_(KRAS)	341	EX-527	SIRT1	7	24	2.99573227355399	NA	5.76009637456702	5.77716816765063	-0.0170717930836073	0.729006423234028	0.519661794039	0.0299859964776181	0.0234178911728558	0.0328517379561794	0.972050124648725	NA	NA	0.112904925787872	0.955333029904561	86.6532679574012
a10644	loss_cnaOV55	178	BAY 61-3606	SYK	4	15	2.07944154167984	NA	2.6792195075051	2.71690629662062	-0.0376867891155217	0.451071718646672	1.47316054166494	0.0279113096478008	0.083549439163669	0.0255822689039233	0.972079389689342	NA	NA	0.941801494272451	0.933126148590252	86.6532679574012
a10645	gain_cnaOV19	310	YM201636	FYV1	3	29	1.63315443905142	NA	2.31297963175029	2.36146177224717	-0.0484821404968874	0.457021605882091	0.897120662807066	0.0554273472851228	0.106082819439822	0.0540419394033218	0.972214418500754	NA	NA	0.652612612385196	0.884300715873603	86.6571633093502
a10646	gain_cnaOV95_(MECOM)	1529	MLN4924	NEDD8-activating enzyme	4	13	0	NA	1.34528884911493	1.3315238204025	0.0137650287124234	1.68520973304909	1.43703103741141	0.00923841385076717	0.0081681398121989	0.00957879708514779	0.972357664670508	NA	NA	0.858387751065208	0.988858183571266	86.6575450525576
a10647	gain_cnaOV94	332	XMD15-27	CAMK2B, CLK2, DYRK1A, MAST1, STK39	7	25	2.32630161961136	NA	5.23237710731637	5.11725649267211	0.115120614644262	0.601352987713746	0.586579456119037	0.195264055713886	0.191436006798491	0.196257494945237	0.972401363350494	NA	NA	0.0123753973726536	0.662798589817362	86.6575450525576
a10648	loss_cnaOV55	1241	CHIR-99021	GSK3B	7	25	2.30258509299405	NA	3.6868658881874	3.67993589243402	0.00692999575337971	1.41407238619408	0.953414189826429	0.00652751796910536	0.00490073621480689	0.00726860983120184	0.972617621970554	NA	NA	0.83203175886604	0.990571029826619	86.6637144394905
a10649	loss_cnaOV40	1494	SN-38	TOP1	8	24	-2.99573227355399	NA	-4.05771046357765	-4.22535609235796	0.167645628780319	2.07589550545295	1.02945443389007	0.124335254436499	0.0807582213747985	0.162849003570585	0.972653266298098	NA	NA	0.220567703375238	0.83156861241706	86.6637144394905
a10650	gain_cnaOV95_(MECOM)	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	3.21415524520288	3.35719359015942	-0.143038344956537	1.20865220296463	0.91083926548813	0.144627223931871	0.118345330944408	0.15704016106495	0.972825048360265	NA	NA	0.194755226267915	0.817754902541604	86.6692241599174
a10651	loss_cnaOV16, loss_cnaOV17	287	KIN001-244	PDPK1 (PDK1)	6	26	2.99573227355399	NA	3.50594383509531	3.5532408659935	-0.047297030898183	0.797688033132462	0.932480632579553	0.0518948839824421	0.0592926419021871	0.0507217300238651	0.972948931839707	NA	NA	0.665260043723804	0.902179609853846	86.6692241599174
a10652	loss_cnaOV55	257	NPK76-II-72-1	PLK3	7	25	2.32630161961136	NA	3.25976968098147	3.22127976214503	0.0384899188364383	1.13711579904941	1.2656872264513	0.0310142702423349	0.0338487239985712	0.0304102925525725	0.972989133553839	NA	NA	0.603211009718756	0.939933425498972	86.6692241599174
a10653	gain_cnaOV95_(MECOM)	1047	Nutlin-3a	MDM2	8	25	2.07944154167984	1.38629436111989	3.79201301055824	3.73352051656583	0.0584924939924112	1.7486738773621	1.5178436449202	0.0371869575023612	0.0334496298879057	0.0385365740326214	0.973195215770133	NA	NA	0.16768519627727	0.933903604688321	86.6794435925703
a10654	loss_cnaOV16, loss_cnaOV17	260	NG-25	MAP3K7 (TAK1)	6	26	2.32630161961136	NA	2.96752566497693	3.02224082606106	-0.0547151610841281	1.29135554425458	1.04583329484205	0.0501698304713451	0.0423703304078909	0.052317287424275	0.973516637353994	NA	NA	0.437403665095812	0.925817974536866	86.6888516520744
a10655	loss_cnaOV33_(ZFHX3)	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.10375647522311	2.17610143940051	-0.072344964177399	1.19282155147384	1.32601504291952	0.0551047242863721	0.0606502825908958	0.0545581775740004	0.97355874816801	NA	NA	0.6884638313033	0.916351482616454	86.6888516520744
a10656	MLL2_mut	1039	SL 0101-1	RSK, AURKB, PIM3	3	30	2.30258509299405	NA	4.95106853849726	4.93632250008329	0.0147460384139642	0.813113832064177	0.826366009771598	0.0178627821939395	0.0181352694204325	0.0178444396787809	0.974001367898826	NA	NA	0.946305939058808	0.978420837929569	86.6888516520744
a10657	ARID1A_mut	275	I-BET	BRD2, BRD3, BRD4	8	23	2.99573227355399	NA	4.025854153231	3.88298914021705	0.142865013013947	1.16947825901279	1.24866139641951	0.116148998110995	0.122161324430731	0.114414534976101	0.974009483206241	NA	NA	0.700622171556648	0.774606159288837	86.6888516520744
a10658	loss_cnaOV52, loss_cnaOV53	254	AC220	FLT3	8	24	0.0237165266173161	NA	2.50942399061487	2.51128462647278	-0.00186063585790253	0.661862267474639	0.626071606724032	0.00293196672504265	0.00281121307156828	0.0029719218024252	0.974026070980261	NA	NA	0.858989700113893	0.994551778434846	86.6888516520744
a10659	gain_cnaOV51_(MYC)	1264	SGC0946	Q8TEK3 (DOT1L)	8	25	-0.693147180559945	NA	2.19298020270173	2.09045837920066	0.102521823501073	0.469680001371042	0.585941670264808	0.182489402193194	0.218280155002986	0.174969333474337	0.974061356429426	NA	NA	0.043512396118791	0.621462978358505	86.6888516520744
a10660	loss_cnaOV58	257	NPK76-II-72-1	PLK3	5	27	2.32630161961136	NA	3.29050209962408	3.2184396786065	0.0720624210175824	0.870824275729322	1.28838282598557	0.0580748789569683	0.0827519661842564	0.055932460107466	0.974083233636829	NA	NA	0.603211585534452	0.879975022209221	86.6888516520744
a10661	gain_cnaOV48_(SOX17)	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.31837712778023	4.37163323656692	-0.0532561087866892	1.17104013501943	1.06357944065414	0.0497219258651661	0.0454776119059367	0.0500725256158909	0.974109382079132	NA	NA	0.354817444606003	0.945675569210167	86.6888516520744
a10662	loss_cnaOV40	134	Etoposide	TOP2	4	15	2.77258872223978	NA	2.13308147465437	2.32337194507111	-0.190290470416743	3.27025960341681	1.36804798920445	0.102768728791994	0.0581881848823026	0.139096341589158	0.974137458780857	NA	NA	0.414347543272496	0.916035599095864	86.6888516520744
a10663	gain_cnaOV94	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.60572657952646	6.71487586359302	-0.109149284066554	2.69016542727084	1.30558260877575	0.0711191493572778	0.0405734468817723	0.0836019745766246	0.974214485093125	NA	NA	0.342396926304369	0.950964890103053	86.6888516520744
a10664	PIK3R1_mut	292	Masitinib	KIT	5	27	2.99573227355399	NA	3.74903023741353	4.06250008389086	-0.31346984647733	1.27537405328394	1.01358271575268	0.297902048617432	0.245786595446396	0.309269131769426	0.974412003804947	NA	NA	0.106798075803544	0.625327534623877	86.6966633649075
a10665	loss_cnaOV20	1019	Bosutinib	SRC, ABL, TEC	4	27	0.693147180559945	NA	2.00106166481017	1.6823745979339	0.318687066876272	1.12321178576944	1.65562924669642	0.19809686131311	0.283728385789649	0.192486975880722	0.974485018082561	NA	NA	0.0424702237089903	0.641833989975868	86.6966633649075
a10666	loss_cnaOV1	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	3	30	0.693147180559945	NA	2.81821236351828	2.79583162113358	0.0223807423847058	0.856159545094093	0.97734990483719	0.023073210883374	0.0261408548359361	0.0228994163440718	0.974607276193234	NA	NA	0.966399619689163	0.969136825410637	86.6994109189433
a10667	loss_cnaOV33_(ZFHX3)	1057	NVP-BEZ235	PI3K (Class 1) and MTORC1/2	4	29	-1.38629436111989	0.693147180559945	-2.09075736477404	-2.32687490002206	0.236117535248018	1.27951375413673	1.65971624208131	0.145141383497478	0.184536926222668	0.142263797425952	0.974739390059222	NA	NA	0.126551507431305	0.754344367521371	86.7030346269192
a10668	gain_cnaOV51_(MYC)	281	CH5424802	ALK	8	24	1.63315443905142	NA	3.92327636632803	3.92904875182166	-0.00577238549363512	1.01050066224843	0.628552086666228	0.00784685404938403	0.00571240149490964	0.00918362314927825	0.974856511837752	NA	NA	0.956067143756474	0.988203893430833	86.7053242348843
a10669	loss_cnaOV38	166	FTI-277	Farnesyl transferase (FNTA)	4	15	0.0237165266173161	NA	2.46765830097961	2.43951189487304	0.0281464061065728	1.35409688617168	0.713387793379456	0.0326603339289579	0.0207861094682439	0.0394545664613041	0.975007548514287	NA	NA	0.625854682193816	0.97020946129658	86.7106295771193
a10670	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	261	TL-1-85	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	3.51591741848251	3.55970363484187	-0.0437862163593632	1.39204305849274	0.930009652440495	0.0452477403850642	0.031454642219741	0.0470814644175586	0.975174074983658	NA	NA	0.730112237318855	0.961988662630693	86.7173113540542
a10671	loss_cnaOV58	279	BIX02189	MAP2K5 (MEK5)	5	27	2.99573227355399	NA	4.40845101595371	4.43539265201135	-0.0269416360576438	1.09642923392273	0.673422781117572	0.0362189627938617	0.0245721613617085	0.0400070161168784	0.975547482767991	NA	NA	0.5269567117647	0.95987605249682	86.7349053690391
a10672	loss_cnaOV42	275	I-BET	BRD2, BRD3, BRD4	4	27	2.99573227355399	NA	3.90412378992095	3.92218845522801	-0.0180646653070662	1.02002311829927	1.25382245244079	0.0146664959019246	0.0177100547850193	0.0144076741263486	0.975554752476993	NA	NA	0.700622804360503	0.975838413599791	86.7349053690391
a10673	loss_cnaOV84	147	NSC-87877	PTPN6 (SHP-1), PTPN11 (SHP-2)	5	14	2.77258872223978	NA	4.992819568746	5.04565711195126	-0.0528375432052579	1.44638598704252	1.11528471444891	0.0439789398029832	0.0365307350033837	0.0473758337406841	0.975884734542996	NA	NA	0.803004727093332	0.943353997160456	86.748070112933
a10674	ARID1A_mut	134	Etoposide	TOP2	5	14	2.77258872223978	NA	2.64661746675908	2.15355841006348	0.493059056695607	0.957130770233644	2.03507439269239	0.268085544897626	0.51514283317341	0.242280605793134	0.97588567637953	NA	NA	0.414349566408371	0.487040369881686	86.748070112933
a10675	PIK3R1_mut	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	28	1.6094379124341	NA	1.19345592188624	1.16330566090017	0.0301502609860709	1.10864291824723	1.55499848963149	0.0200352322877343	0.0271956465781953	0.0193892541935626	0.976168856725387	NA	NA	0.814194239032035	0.959706677856149	86.7557468555692
a10676	gain_cnaOV50	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.1057914722257	2.17579995836308	-0.0700084861373793	1.137664845567	1.33161264087967	0.0533244249244549	0.0615370039868708	0.0525742126412465	0.976183443660081	NA	NA	0.688464940742671	0.915677516063334	86.7557468555692
a10677	gain_cnaOV50	1028	VX-702	p38	4	27	0.693147180559945	NA	3.36223761825508	3.32174427398697	0.0404933442681163	0.839869930924854	0.943655637706858	0.0433800962876311	0.0482138278525171	0.0429111453904071	0.976246340621135	NA	NA	0.520801591110568	0.933526228416952	86.7557468555692
a10678	SMAD4_mut	257	NPK76-II-72-1	PLK3	3	29	2.32630161961136	NA	3.29416278900351	3.22303080874088	0.0711319802626358	0.235584461467488	1.28297476984929	0.0573199820810257	0.301938335913773	0.0554430078706782	0.976519936346287	NA	NA	0.603212782286776	0.798090032252801	86.7623651066579
a10679	gain_cnaOV50	203	BMS-345541	IKBKB	4	28	2.77258872223978	NA	3.40767150731754	3.25740795741704	0.150263549900495	1.10387639106252	1.04228659774584	0.143298063795986	0.136123528972171	0.144167209120285	0.976729842947009	NA	NA	0.093897098116105	0.810894427392314	86.7623651066579
a10680	gain_cnaOV50	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-2.1269986199176	-1.97087920605701	-0.156119413860593	1.99706794152482	2.05460168345566	0.0761890931322715	0.0781743127584289	0.0759852457620953	0.976802807133933	NA	NA	0.281197150819387	0.891064148846068	86.7623651066579
a10681	RB1_mut	1242	(5Z)-7-Oxozeaenol	MAP3K7 (TAK1)	3	29	2.30258509299405	NA	0.827416654596327	0.873580512191993	-0.0461638575956662	0.382337481295353	1.29661633071515	0.036739034998393	0.12074112493304	0.0356033288352959	0.976914380778369	NA	NA	0.845858630700389	0.890827814362455	86.7623651066579
a10682	loss_cnaOV55	202	GSK-1904529A	IGF1R	4	15	0.0237165266173161	NA	2.50217795650835	2.48950097970384	0.0126769768045132	0.218529371428099	0.856394629693007	0.0161991903632157	0.0580104025452899	0.0148027280472993	0.97692291737792	NA	NA	0.75203444635066	0.959609065578045	86.7623651066579
a10683	loss_cnaOV1	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.59163050102352	5.53327496750413	0.0583555335193937	0.73522250388787	1.00403445986753	0.0590409531872104	0.079371255927027	0.0581210464898717	0.976976983601812	NA	NA	0.307191779518684	0.908216605540169	86.7623651066579
a10684	gain_cnaOV94	1114	Cetuximab	EGFR	7	25	4.18661983833127	NA	5.75311590470849	5.84177979452287	-0.0886638898143763	1.2736068225225	1.30235983041016	0.0683786602619021	0.0696163747291879	0.0680794107312517	0.976979944698739	NA	NA	0.573377343819497	0.874596514550212	86.7623651066579
a10685	SMAD4_mut	151	QS11	ARFGAP	3	16	2.32630161961136	NA	3.99888266073707	3.72326012924261	0.275622531494463	2.31077749098951	1.32382061580332	0.186910051973551	0.119276967414304	0.208202326058512	0.977097120561857	NA	NA	0.0674471266943499	0.857749231342183	86.7623651066579
a10686	loss_cnaOV54	1494	SN-38	TOP1	11	21	-2.99573227355399	NA	-4.06245626707929	-4.24681957082572	0.184363303746427	0.796286946000931	1.55117359181012	0.136830293677753	0.231528728019876	0.118854075855744	0.977159317754791	NA	NA	0.220570507045612	0.660047255501199	86.7623651066579
a10687	loss_cnaOV85	345	KIN001-270	CDK9	7	25	2.99573227355399	NA	5.23430639212785	5.17861738139059	0.0556890107372556	0.801324256278882	0.771234032595864	0.0716399949030698	0.069496224906331	0.0722076676904602	0.977330947239173	NA	NA	0.336619113474537	0.873336958257099	86.7623651066579
a10688	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1373	Dabrafenib	BRAF	3	29	2.30258509299405	NA	3.72331772046225	3.63832736379635	0.0849903566659038	3.28132198047691	1.92519243545411	0.0415846706867981	0.0259012547904706	0.0441464214697356	0.977485590545456	NA	NA	0.748943493844352	0.968601230247963	86.7623651066579
a10689	TP53_mut	328	SNX-2112	HSP90	22	10	0.940007258491471	NA	0.703171222647574	0.680700326124071	0.0224708965235029	2.48410603656692	1.92178959921607	0.00964537821610872	0.00904586849060521	0.0116926933794777	0.977557815604457	NA	NA	0.946180147533351	0.978008879776334	86.7623651066579
a10690	gain_cnaOV18_(CCNE1)	176	IPA-3	PAK1, PAK2, PAK3	4	15	3.46573590279973	NA	4.97304662895164	4.70404665260091	0.26899997635073	1.66721889111119	1.56933985617785	0.169496708382474	0.161346526112982	0.171409637811585	0.977582250684501	NA	NA	0.125633312796688	0.784452615274896	86.7623651066579
a10691	loss_cnaOV84	309	Y-39983	ROCK	6	26	2.99573227355399	NA	5.02671268105556	4.94988426893231	0.0768284121232519	1.52531283124372	1.18365613588191	0.0616048691670285	0.0503689541906016	0.0649077124633069	0.97760099546794	NA	NA	0.375574009190188	0.911474305715773	86.7623651066579
a10692	loss_cnaOV85	328	SNX-2112	HSP90	7	25	0.940007258491471	NA	0.728563327027191	0.68707307481188	0.041490252215311	2.45731749857205	2.29664173123222	0.0178095465632602	0.0168843677056062	0.0180656180069715	0.977936019097204	NA	NA	0.946180172467653	0.96891864592164	86.764580099674
a10693	loss_cnaOV58	333	T0901317	LXR	5	27	2.32630161961136	NA	4.94362294674577	4.71811634486541	0.225506601880359	1.02742075361231	1.140003543659	0.200335760236755	0.21948807349618	0.197812193773157	0.978023915894609	NA	NA	0.00536208721743613	0.673404760586383	86.764580099674
a10694	loss_cnaOV39	186	Bexarotene	Retinioic acid X family agonist	4	14	2.07944154167984	NA	3.78826907762223	3.77724552936063	0.0110235482616057	1.22575510614182	0.932157551230332	0.0110919199280053	0.00899327133647707	0.0118258423665141	0.978259823481229	NA	NA	0.810220194465906	0.987494853276873	86.764580099674
a10695	gain_cnaOV4_(KRAS)	1066	AZD6482	PI3Kbeta	7	26	1.6094379124341	NA	2.39974805579211	2.37355822788149	0.0261898279106152	1.44639318879592	1.28477824540008	0.0198768196879159	0.0181069906257077	0.0203847068584662	0.978306120251265	NA	NA	0.112130166718548	0.966276054222722	86.764580099674
a10696	loss_cnaOV83	256	JW-7-24-1	LCK	5	27	2.32630161961136	NA	1.97330175579657	1.93305577112774	0.0402459846688281	0.63345774563082	1.43186489649222	0.0297476431624432	0.0635338109706902	0.028107389717719	0.978364534480958	NA	NA	0.840050516241599	0.920404927269305	86.764580099674
a10697	loss_cnaOV21, loss_cnaOV22	293	MP470	PDGFR	3	29	2.99573227355399	NA	4.01642457695677	4.05263770863719	-0.0362131316804204	0.169174992225832	1.84333612957877	0.0203288380196684	0.214057238625904	0.0196454304233138	0.978430795153167	NA	NA	0.624400118949683	0.919646130176609	86.764580099674
a10698	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	5	27	0.246860077931526	2.32630161961136	0.958487336459573	1.01263893562112	-0.0541515991615519	1.22639101264622	1.60733142576629	0.0346699665449155	0.0441552478802886	0.0336903754219421	0.978464149682213	NA	NA	0.792293092038931	0.93392921782087	86.764580099674
a10699	gain_cnaOV95_(MECOM)	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	5	14	2.07944154167984	NA	3.452493550459	3.46856116140352	-0.0160676109445124	1.13900723277837	1.12268263710289	0.0142627333447141	0.0141066803459349	0.0143118014062952	0.978529080442712	NA	NA	0.7755548538307	0.979075967313571	86.764580099674
a10700	loss_cnaOV35	1161	ZG-10	IRAK1	5	18	2.30258509299405	NA	1.73422981253893	1.53411645158859	0.200113360950338	1.23908525020405	1.27605566280859	0.157681726265077	0.161500882136547	0.156821811761636	0.978591082087873	NA	NA	0.167611016694836	0.760795735233296	86.764580099674
a10701	loss_cnaOV20	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.60363630127533	1.76174419658984	-0.158107895314505	1.88923197507484	1.68620771771613	0.0922580900581561	0.0836889791198044	0.0937653728264592	0.978762392393692	NA	NA	0.23205206228489	0.867616203670682	86.764580099674
a10702	loss_cnaOV59	295	NVP-BHG712	EPHB4	4	28	2.32630161961136	NA	3.12906851992368	3.26856707799891	-0.139498558075234	1.54186668681437	1.03331271087712	0.127413375648343	0.0904738128582637	0.135001298838976	0.978838491741525	NA	NA	0.0639530610912212	0.870708058563182	86.764580099674
a10703	loss_cnaOV102	228	KIN001-102	AKT1	3	29	2.32630161961136	NA	2.90914649239307	2.77641682013687	0.132729672256204	0.150208375731303	1.28107800738602	0.107191642406996	0.883636958391954	0.103607798659375	0.979008064359984	NA	NA	0.0967850077181698	0.604149698713118	86.764580099674
a10704	loss_cnaOV81_(RB1)	249	XL-184	VEGFR, MET, RET, KIT, FLT1, FLT3, FLT4, Tie2,AXL	4	28	1.63315443905142	NA	2.74990638950503	2.8800331772297	-0.130126787724671	0.70215533055188	0.819695118426522	0.160906561593852	0.185324787924623	0.15875022895642	0.979018141249716	NA	NA	0.0201977411830122	0.75057851819666	86.764580099674
a10705	loss_cnaOV1	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.7813713298947	2.70927702534597	0.0720943045487346	0.300240661713464	0.588411636763693	0.125660871724967	0.240121721479345	0.122523587305748	0.979166841369651	NA	NA	0.137993081202217	0.743315945227518	86.764580099674
a10706	loss_cnaOV70	304	SB52334	ALK5	3	29	2.99573227355399	NA	4.28393900580224	4.37519580090947	-0.0912567951072241	2.13197015933433	0.950766242871171	0.0852192965527686	0.0428039739241554	0.0959823676865539	0.979371081458342	NA	NA	0.354820643550258	0.9479396896015	86.764580099674
a10707	loss_cnaOV21, loss_cnaOV22	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	3	28	1.6094379124341	NA	1.2990957745934	1.34426939573282	-0.0451736211394138	2.85679242874704	1.17980886488281	0.0331336120941031	0.0158127068263151	0.0382889317787088	0.979402783748965	NA	NA	0.583309416370126	0.980733599429312	86.764580099674
a10708	loss_cnaOV40	157	JNK-9L	JNK	4	15	1.63315443905142	NA	-0.148879956962447	-0.000198101640101054	-0.148681855322346	1.5027870356387	0.881095088216076	0.145944428925687	0.0989374088252999	0.168746662319248	0.979484775452303	NA	NA	0.195389739344018	0.860065202736142	86.764580099674
a10709	SMARCA4_mut	262	VX-11e	ERK	3	29	1.63315443905142	NA	2.95280954504662	2.8496018675305	0.103207677516121	1.54584340648667	1.09333117353311	0.091402602942054	0.0667646393438305	0.094397452496122	0.979496816358798	NA	NA	0.393734046040144	0.919634567204055	86.764580099674
a10710	loss_cnaOV82	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-4.05899988581922	-4.0598557554772	0.000855869657977237	1.68871392574129	1.5256883884104	0.000556668044943934	0.000506817433628693	0.000560972780863173	0.979596868967079	NA	NA	0.864965440153713	0.99939413060179	86.764580099674
a10711	loss_cnaOV35	1091	BMS-536924	IGF1R	5	27	1.38629436111989	NA	2.37861989230097	2.39629512218308	-0.0176752298821152	1.27122876520639	0.890780589658585	0.0185986948241018	0.0139040512344334	0.0198424057363999	0.97963379351867	NA	NA	0.736411786743164	0.977462026166752	86.764580099674
a10712	loss_cnaOV21, loss_cnaOV22	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	0.998169942152369	1.00479924543487	-0.00662930328249656	1.73266982678646	1.54914116628903	0.00424398340251892	0.00382606263467504	0.00427934098373816	0.979743413353585	NA	NA	0.792293390781398	0.995420110336336	86.764580099674
a10713	loss_cnaOV39	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.79067298445413	-4.60531998797418	-0.185352996479956	3.24247980457569	1.56676499960201	0.0888600561248681	0.0571639632784733	0.118302997914199	0.979754275129064	NA	NA	0.355166928001479	0.907354119672619	86.764580099674
a10714	NF1_mut	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	27	2.30258509299405	NA	2.17442327462	2.1656322839343	0.00879099068569644	0.972086912078617	1.3469022683969	0.00669484179152055	0.00904342047656895	0.00652682150142905	0.97991267624265	NA	NA	0.688466317554854	0.987895928067426	86.764580099674
a10715	loss_cnaOV87, loss_cnaOV88	1028	VX-702	p38	3	28	0.693147180559945	NA	3.36236669898031	3.32317663477598	0.0391900642043277	2.03048717677988	0.794065349314887	0.0419826176766676	0.0193008183713224	0.0493537014782732	0.980079388101275	NA	NA	0.520803570133427	0.976473559980648	86.764580099674
a10716	loss_cnaOV52, loss_cnaOV53	262	VX-11e	ERK	8	24	1.63315443905142	NA	2.80212455048035	2.87832859957006	-0.0762040490897093	1.40943910022739	1.02867995784299	0.0674928870453088	0.0540669327801501	0.07407945348668	0.980253826647543	NA	NA	0.393734438307596	0.890838722425017	86.764580099674
a10717	gain_cnaOV48_(SOX17)	208	SB-715992	KIF11	3	29	-2.05572501506252	NA	-1.06925564604626	-1.34306906287305	0.273813416826789	0.469765281276865	1.9476322924702	0.145220822140339	0.582872825515201	0.140587839853235	0.980267260591843	NA	NA	0.075872935858395	0.555477248975423	86.764580099674
a10718	PTEN_mut	222	BX-912	PDPK1 (PDK1)	3	29	2.32630161961136	NA	3.04230361450079	3.44794618301596	-0.405642568515169	0.83623371606463	1.24852562892015	0.331038716783092	0.485082771386149	0.324897270123328	0.980629312842315	NA	NA	0.32976177976243	0.503586913680696	86.764580099674
a10719	loss_cnaOV87, loss_cnaOV88	1026	17-AAG	HSP90	3	30	0	NA	-0.185927659207515	-0.565322608198302	0.379394948990788	1.26748637116038	2.36799344478343	0.164037897666683	0.299328622084869	0.16021790509031	0.980819902597878	NA	NA	0.062790180946772	0.680781915399763	86.764580099674
a10720	loss_cnaOV81_(RB1)	294	MPS-1-IN-1	MPS1	4	27	2.99573227355399	NA	4.21687390178358	4.29377153321323	-0.0768976314296532	0.514132703823619	0.85424380205917	0.0931434048005916	0.149567671649291	0.0900183662372383	0.980934367097851	NA	NA	0.319988473632283	0.809664245743762	86.764580099674
a10721	loss_cnaOV83	200	LAQ824	HDAC	4	15	0.0237165266173161	NA	-2.82205998775414	-2.7273198210445	-0.0947401667096317	1.50865173850089	1.17803295835293	0.0762321368008482	0.0627979037784909	0.0804223396619503	0.980961786704274	NA	NA	0.384257550767096	0.912841674086116	86.764580099674
a10722	loss_cnaOV83	306	TG101348	JAK2	5	27	2.32630161961136	NA	2.85667043841657	2.8180193922859	0.0386510461306755	0.615734115857229	1.4934009296756	0.027444337134025	0.0627722991714781	0.025881225438283	0.981053780914482	NA	NA	0.629616919502748	0.923948003840547	86.764580099674
a10723	loss_cnaOV55	1036	PLX4720	BRAF	8	25	2.30258509299405	NA	4.40524112815858	4.27673841871649	0.128502709442092	1.17758871828366	1.35796562934101	0.0973953539708901	0.109123590814784	0.094628837921657	0.981183596295565	NA	NA	0.373977602301108	0.799911093523863	86.764580099674
a10724	ARID1A_mut	1248	FK866	NAMPT	9	23	0	NA	-2.79067658636761	-1.28484168253413	-1.50583490383348	1.98598937348617	2.90543114925025	0.55955297483317	0.758229084171868	0.518282769915944	0.981396503811388	NA	NA	0.0458467017224314	0.107798313772525	86.764580099674
a10725	loss_cnaOV84	140	Vinorelbine	Microtubules	5	14	-2.74887219562247	NA	-3.53260733267932	-3.42932376388966	-0.103283568789664	2.2998107250276	1.60358507739517	0.0576389103609152	0.0449095952400277	0.0644079133970462	0.981441658307022	NA	NA	0.684799567695302	0.929452646704056	86.764580099674
a10726	loss_cnaOV59	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-0.954956494833472	-1.2242320660567	0.269275571223224	1.32638938512586	1.34254540176596	0.200914536265433	0.203013967273021	0.200570923611986	0.981519874818658	NA	NA	0.0512043610096944	0.729728371203615	86.764580099674
a10727	loss_cnaOV70	211	TL-2-105	CRAF	3	29	2.32630161961136	1.63315443905142	4.46447722959932	4.40342662306524	0.0610506065340735	0.397746391773466	0.650680929213522	0.0958481762980202	0.15349128941651	0.0938257197853721	0.981593122477501	NA	NA	0.274114135317545	0.828080276452956	86.764580099674
a10728	gain_cnaOV26	255	CP724714	ERBB2	3	29	2.32630161961136	NA	4.38517649410993	4.41816193690427	-0.0329854427943372	0.808861157250795	0.967991781727092	0.034424180717201	0.0407801048407988	0.0340761599602473	0.981795850536122	NA	NA	0.787769516618559	0.952122067438368	86.764580099674
a10729	loss_cnaOV55	344	THZ-2-49	CDK9	7	25	2.99573227355399	NA	2.74311890938602	2.54358764681024	0.199531262575787	2.57518731366487	2.29293275555149	0.0848312975123128	0.0774822326581848	0.087020110857022	0.981803355157483	NA	NA	0.388939717996312	0.8570592009077	86.764580099674
a10730	loss_cnaOV102	306	TG101348	JAK2	3	29	2.32630161961136	NA	2.85263428023895	2.8211025152788	0.0315317649601505	0.787378472437561	1.44254968130981	0.0223885846079	0.0400465164643563	0.021858356331631	0.98182165381312	NA	NA	0.629617187569383	0.955515827237421	86.764580099674
a10731	loss_cnaOV40	154	CHIR-99021	GSK3B	4	15	0.940007258491471	NA	3.41286930567375	3.29466728437009	0.118202021303664	1.40672716547893	0.875179182900881	0.11940284525454	0.0840262591100395	0.135060366623289	0.981901896154122	NA	NA	0.194764037416108	0.881356024299162	86.764580099674
a10732	loss_cnaOV20	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-3.08234511230775	-3.34968329318367	0.267338180875921	1.93748623921447	1.8238514582765	0.145614346999448	0.137981976576159	0.146578922128093	0.982086760210539	NA	NA	0.141964626366384	0.808621296735104	86.764580099674
a10733	KRAS_mut	269	NSC-207895	MDM4	7	24	2.99573227355399	NA	3.84683165210824	3.89609291756387	-0.0492612654556246	1.27346753567187	1.67957202438081	0.0307113508498124	0.0386827807350697	0.0293296534715653	0.982118970966491	NA	NA	0.717376313844069	0.934857083922362	86.764580099674
a10734	PTEN_mut	1372	Trametinib	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	0	NA	-1.35530713941925	-2.07731941026368	0.722012270844426	1.09868882461379	2.11115724085507	0.354743369229665	0.657158109438521	0.341998339523016	0.98214048108531	NA	NA	0.281199904299102	0.321987001597198	86.764580099674
a10735	gain_cnaOV18_(CCNE1)	1268	XAV 939	TNKS1 (tankyrase-1)	4	28	1.6094379124341	NA	2.75971329621022	2.86959828975339	-0.10988499354317	0.979479091294779	1.09127014433447	0.101687780107011	0.112187176346881	0.100694584300375	0.982192590147127	NA	NA	0.309821818352632	0.845941565084991	86.764580099674
a10736	loss_cnaOV82	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.953092082110416	-1.21104794940399	0.257955867293577	1.57987735269625	1.31380561227299	0.192300384870278	0.163275881417848	0.196342491525282	0.982265383429051	NA	NA	0.0512045908283558	0.808940904085208	86.764580099674
a10737	loss_cnaOV57_(ZNRF3)	291	KIN001-266	MAP3K8 (COT)	4	28	2.99573227355399	NA	3.29539014089594	3.30344848529899	-0.0080583444030462	0.600051708400775	1.15936549525184	0.00721996855272878	0.0134294166489799	0.00695065053777176	0.9823435173857	NA	NA	0.951235461118296	0.983314069514585	86.764580099674
a10738	gain_cnaOV18_(CCNE1)	155	AP-24534	ABL	4	15	-0.669430653942629	NA	0.744711773853051	0.800241258562147	-0.055529484709096	1.65111168745305	1.17908509877527	0.0435475989808341	0.0336315738850798	0.0470954002953436	0.982423737252676	NA	NA	0.588475110283759	0.952814865206208	86.764580099674
a10739	RB1_mut	1375	Temozolomide	DNA akylating agent	3	30	3.40119738166216	NA	5.94856281804441	5.94708840135049	0.0014744166939149	0.891941559977229	0.693826273533111	0.00208167988295108	0.00165304181358311	0.00212505168823726	0.982513536370911	NA	NA	0.909252722346695	0.998008959236036	86.764580099674
a10740	gain_cnaOV95_(MECOM)	155	AP-24534	ABL	5	14	-0.669430653942629	NA	0.828560563957407	0.774261653861242	0.0542989100961652	1.39629561999873	1.23544454730732	0.0425834183980859	0.0388878324320853	0.0439509083710077	0.982554796996001	NA	NA	0.588475196188027	0.94107509165174	86.764580099674
a10741	gain_cnaOV94	276	CAY10603	HDAC6	6	25	2.99573227355399	NA	1.35475280218598	1.45201524243722	-0.0972624402512408	1.17023432259842	1.91090074615679	0.0538845759472968	0.0831136451674707	0.0508987400035588	0.982612350355235	NA	NA	0.616945975489916	0.876249276382868	86.764580099674
a10742	gain_cnaOV50	1166	QL-VIII-58	MTOR, ATR	3	20	2.30258509299405	NA	-0.953522451408147	-1.21098339400933	0.257460942601187	1.19664205846491	1.35577525842174	0.191929739495178	0.215152844394811	0.189899425440834	0.98277501422303	NA	NA	0.0512047424845854	0.756643228020097	86.764580099674
a10743	loss_cnaOV21, loss_cnaOV22	1219	PFI-1	BRD2, BRD3, BRD4	3	29	2.30258509299405	NA	2.31634009951573	2.36626631519101	-0.0499262156752733	0.286091585209658	0.905314029704536	0.0568810436067314	0.174511304268826	0.0551479531269029	0.983000734832	NA	NA	0.610178354642583	0.837731678656781	86.764580099674
a10744	loss_cnaOV57_(ZNRF3)	271	VNLG/124	HDAC, RAR 	4	27	1.63315443905142	NA	4.38225376912875	4.32151782545432	0.0607359436744277	0.402642119594661	0.610079044653008	0.102594431371841	0.15084349281583	0.0995542204026565	0.983137158097669	NA	NA	0.257074255399588	0.804191003529038	86.764580099674
a10745	PIK3CA_mut	1069	EHT 1864	Rac GTPases	7	26	2.30258509299405	NA	3.98115120487892	4.29614034049957	-0.314989135620648	1.04248884873293	0.961016653137477	0.322300303636941	0.302151083921418	0.327766573651235	0.983160600954091	NA	NA	0.2123045232484	0.489223212758589	86.764580099674
a10746	loss_cnaOV87, loss_cnaOV88	309	Y-39983	ROCK	3	29	2.99573227355399	NA	5.02509740912188	4.95799913280026	0.0670982763216186	2.23808686131843	1.14419984001728	0.0537932281770268	0.029980193119981	0.0586420955281771	0.983269990023935	NA	NA	0.375576888798973	0.963576612315058	86.764580099674
a10747	PIK3CA_mut	309	Y-39983	ROCK	6	26	2.99573227355399	NA	4.73038078797201	5.01826855195159	-0.28788776397958	0.957512571425297	1.2915034500943	0.231776761121607	0.300662124520252	0.222909016587264	0.983279829389938	NA	NA	0.375576893071092	0.550714209289233	86.764580099674
a10748	loss_cnaOV70	1026	17-AAG	HSP90	3	30	0	NA	-0.240865731536018	-0.559828800965452	0.318963069429434	0.734697366723715	2.38430918190354	0.137861304700229	0.434142116027729	0.133775884373681	0.983285889857387	NA	NA	0.0627907657861777	0.614260882212762	86.764580099674
a10749	gain_cnaOV51_(MYC)	1047	Nutlin-3a	MDM2	8	25	2.07944154167984	1.38629436111989	3.91846332163687	3.69305641702067	0.225406904616197	1.62119641783563	1.55472757690317	0.143572861810757	0.139037381366241	0.144981608331139	0.983377134314389	NA	NA	0.167690043707701	0.735866448543496	86.764580099674
a10750	loss_cnaOV56	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.3796071906503	2.3949740064999	-0.0153668158496019	1.52382021761159	0.895453829610627	0.0161694730486071	0.0100844021309072	0.0171609248198579	0.983408323474115	NA	NA	0.736412760623599	0.9877706494954	86.764580099674
a10751	TP53_mut	292	Masitinib	KIT	22	10	2.99573227355399	NA	4.00056803048611	4.04201567814263	-0.0414476476565202	1.11309013475341	0.919044741267421	0.0391526065516102	0.0372365600614206	0.0450986179403641	0.983525674745218	NA	NA	0.106801616508373	0.913088857401136	86.764580099674
a10752	gain_cnaOV49	238	CAL-101	PI3Kdelta	3	29	2.99573227355399	2.32630161961136	4.42018247675914	4.38381238006665	0.0363700966924858	0.578557190116421	1.01668256168843	0.0366079220330743	0.0628634425667879	0.0357733063032822	0.983656741186126	NA	NA	0.514130969302627	0.929715792664454	86.764580099674
a10753	loss_cnaOV33_(ZFHX3)	1033	Vismodegib	SMO	4	27	2.30258509299405	NA	5.01651260969035	4.89530342964569	0.121209180044656	1.31134099371051	0.799277686743191	0.139899820896894	0.092431473297947	0.151648397115333	0.983762591176374	NA	NA	0.156848217003426	0.867552051529384	86.764580099674
a10754	loss_cnaOV38	182	Obatoclax Mesylate	BCL2, BCL2L1, MCL1	4	15	2.77258872223978	NA	-0.846995158116299	-0.495347266716118	-0.351647891400181	2.78914369335136	1.62493351472957	0.186706967464072	0.126077366411212	0.216407556501599	0.983777455459245	NA	NA	0.0447861807843405	0.822449136477491	86.764580099674
a10755	gain_cnaOV50	268	YM155	BIRC5 (Survivin)	4	26	1.63315443905142	NA	-4.18937506403113	-4.14527802939003	-0.0440970346410978	1.07141505934437	2.47726070816551	0.0186305782720637	0.0411577513835602	0.0178007242014318	0.983888441252048	NA	NA	0.928530539626581	0.95268091485987	86.764580099674
a10756	loss_cnaOV38	193	GW-2580	CSF1R (cFMS)	8	24	2.99573227355399	NA	5.77617318018104	5.7099080804676	0.0662650997134406	0.750260418782068	0.558494439557426	0.10886902961652	0.0883227983971377	0.118649524543077	0.984020868177963	NA	NA	0.195090078655999	0.823223979836575	86.764580099674
a10757	loss_cnaOV35	300	CX-5461	RNA Pol I	5	26	2.32630161961136	NA	3.57216201815803	3.53309915321009	0.0390628649479385	2.16120372637345	1.64252285690488	0.0226665416929265	0.0180745870790658	0.0237822352265754	0.984047095698655	NA	NA	0.700404677724562	0.970919169836108	86.764580099674
a10758	gain_cnaOV49	1031	Elesclomol	HSP70	3	28	-1.6094379124341	NA	-4.0979606598935	-4.05568138682638	-0.0422792730671153	1.48043026215642	1.54157082994013	0.0274999250554677	0.0285587738564129	0.0274260982667642	0.984125896062188	NA	NA	0.864966067492775	0.9661511166446	86.764580099674
a10759	loss_cnaOV20	303	PIK-93	PI4K, PI3K	5	27	2.99573227355399	NA	2.81416570964359	2.92220389793756	-0.10803818829397	1.0697761455098	1.28378127796786	0.0859250680042469	0.100991397824153	0.0841562267249971	0.984210730040626	NA	NA	0.2344879764573	0.847248672231251	86.764580099674
a10760	loss_cnaOV33_(ZFHX3)	1004	Vinblastine	Microtubules	4	27	-2.30258509299405	NA	-3.08466241035389	-3.34933998976943	0.264677579415539	1.96228805395753	1.82084146445813	0.144161528382776	0.134882123387409	0.145360035226518	0.984301146885021	NA	NA	0.141965441513277	0.812585583701157	86.764580099674
a10761	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1042	BIRB 0796	p38, JNK2	5	28	2.30258509299405	NA	4.37979237509499	4.40066038419681	-0.0208680091018234	1.16913412639731	0.813384353894692	0.0240546739877011	0.0178491146829562	0.0256557788478498	0.984435531251164	NA	NA	0.870309885107317	0.971022943210212	86.764580099674
a10762	gain_cnaOV48_(SOX17)	305	TPCA-1	IKK	3	29	2.99573227355399	NA	3.33799536916325	3.32387083649627	0.0141245326669712	1.35435356108167	1.23215862261041	0.0113845142519558	0.0104289847738803	0.0114632421571238	0.984515041334125	NA	NA	0.993651912161657	0.987527252799896	86.764580099674
a10763	loss_cnaOV33_(ZFHX3)	1017	Olaparib	PARP1, PARP2	4	27	1.6094379124341	NA	4.11919012855852	3.94748051492262	0.171709613635905	1.44586157927337	1.14050427601162	0.146039356184297	0.118759372333691	0.150555870107195	0.984539671356868	NA	NA	0.0847815361766072	0.832604741276853	86.764580099674
a10764	loss_cnaOV39	194	AUY922	HSP90	5	14	-1.36257783450257	NA	-2.40678837230556	-2.59517849186801	0.188390119562452	2.97480512143094	1.62668546611732	0.0929744190707481	0.0633285582995877	0.11581225964483	0.984574471293495	NA	NA	0.350532889104739	0.898298215554643	86.764580099674
a10765	loss_cnaOV85	155	AP-24534	ABL	6	13	-0.669430653942629	NA	0.723585114524115	0.818535022053825	-0.0949499075297098	1.56784710765864	1.1300404320023	0.0744988341862929	0.0605606931096132	0.0840234604362518	0.984598948504263	NA	NA	0.588476452776873	0.897515229342293	86.764580099674
a10766	TP53_mut	230	GSK429286A	ROCK2	22	10	2.99573227355399	2.32630161961136	5.53023332765806	5.5574732352213	-0.0272399075632324	1.12004512560347	0.574178062083779	0.0275579017610209	0.024320366153601	0.0474415679769697	0.984655268776792	NA	NA	0.30719563685636	0.92826426113685	86.764580099674
a10767	loss_cnaOV36	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.93515880984367	4.04277932216856	-0.107620512324891	1.48600930913005	1.51127743848171	0.0712904614952493	0.0724225021092868	0.0712116184524074	0.98492551619523	NA	NA	0.332753636009454	0.914182187814319	86.764580099674
a10768	loss_cnaOV21, loss_cnaOV22	226	GSK1070916	AURKB	3	29	0.940007258491471	2.32630161961136	2.30686876960252	2.31470447926906	-0.00783570966653802	1.3040557571607	1.46642323411998	0.00538106964649823	0.00600872288129659	0.00534341620087621	0.984971905380004	NA	NA	0.822054223956344	0.99290400377419	86.764580099674
a10769	SMAD4_mut	1061	SB590885	BRAF	4	29	1.6094379124341	NA	3.9514365541767	3.92424372357753	0.0271928305991715	2.33056955954023	1.12767488928758	0.0210158952877337	0.011667890575442	0.024114069451658	0.985054015744222	NA	NA	0.575472526833663	0.983035273159296	86.764580099674
a10770	gain_cnaOV50	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.32515704072132	4.27119499138264	0.0539620493386819	0.699488704703869	0.922894225237439	0.0597557124588963	0.0771449902990597	0.0584704594123976	0.985158673420064	NA	NA	0.524163598902631	0.895964794888161	86.764580099674
a10771	gain_cnaOV72_(ASXL1)	276	CAY10603	HDAC6	4	27	2.99573227355399	NA	1.50883251885465	1.42198399254177	0.0868485263128804	2.16769911256727	1.75857218998243	0.0481101774374869	0.0400648437826885	0.0493858181129022	0.985327810414119	NA	NA	0.616946847220944	0.943079799426679	86.764580099674
a10772	gain_cnaOV95_(MECOM)	156	AZD6482	PI3Kbeta	5	14	1.63315443905142	NA	2.13549911828628	2.14061047343721	-0.00511135515093564	2.16655452080211	1.32357803382304	0.00326945235109111	0.00235920910452938	0.00386177091211762	0.985425413164038	NA	NA	0.948315094964895	0.996233836974894	86.764580099674
a10773	gain_cnaOV95_(MECOM)	1259	BMN-673	PARP1	8	25	2.30258509299405	NA	1.9449227564278	1.88615964669639	0.0587631097314081	1.47511232810805	1.36504328669236	0.0422555763792193	0.0398363627038331	0.0430485320899949	0.9856888561397	NA	NA	0.0352971060396219	0.922261165408124	86.764580099674
a10774	loss_cnaOV39	282	EKB-569	EGFR	9	23	0.916290731874155	2.99573227355399	1.77537368027191	1.64770001648979	0.127673663782115	1.20189549410787	1.58846823902771	0.0853897714796786	0.106226926058063	0.0803753330694628	0.985698439638197	NA	NA	0.329450299707533	0.808564873739588	86.764580099674
a10775	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	304	SB52334	ALK5	5	27	2.99573227355399	NA	4.30706015867692	4.37767386853321	-0.0706137098562838	1.19567643502821	1.05035544915705	0.0659404078069115	0.0590575408092053	0.0672283938860449	0.985725983167722	NA	NA	0.354823541625198	0.906317359476118	86.764580099674
a10776	gain_cnaOV50	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	4	29	1.6094379124341	NA	1.15392591556969	1.16979773973645	-0.0158718241667621	1.42670641876387	1.51303151282294	0.0105468060637065	0.0111248004200569	0.0104900816884833	0.985788325338468	NA	NA	0.814196015043036	0.984476799221828	86.764580099674
a10777	loss_cnaOV70	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.93403834864609	4.04289523194762	-0.108856883301536	1.33952521199466	1.52101857287342	0.072109847641257	0.081265273939443	0.0715684116176765	0.986003180448318	NA	NA	0.33275404666333	0.904483125565569	86.764580099674
a10778	TP53_mut	166	FTI-277	Farnesyl transferase (FNTA)	12	7	0.0237165266173161	NA	2.44988387567081	2.4378150169949	0.0120688586759048	0.868347105255973	0.849824421637129	0.0140033493474415	0.0138986571186267	0.0142015907858413	0.986014398820823	NA	NA	0.625862133769763	0.976821828366909	86.764580099674
a10779	TP53_mut	281	CH5424802	ALK	22	10	1.63315443905142	NA	3.92892335494291	3.92470671656001	0.00421663838289765	0.853642314781815	0.321772393741487	0.00573199188488894	0.00493958454247362	0.0131044131346001	0.986052795000217	NA	NA	0.956067673222239	0.98400209474567	86.764580099674
a10780	ARID1A_mut	1268	XAV 939	TNKS1 (tankyrase-1)	9	23	1.6094379124341	NA	3.07680010953453	2.76940888313588	0.30739122639865	0.743409011400207	1.16855427118113	0.286798978032124	0.413488700950343	0.263052588980699	0.986081145846656	NA	NA	0.309823434120571	0.385539541705209	86.764580099674
a10781	loss_cnaOV54	301	PHA-793887	CDK-pan	10	22	2.32630161961136	NA	3.06564407780375	2.98447378975535	0.0811702880484027	1.19059548084804	1.79286337703872	0.0496261179322742	0.068176210437643	0.045274106821498	0.986098288500477	NA	NA	0.665444472781018	0.880938173609264	86.764580099674
a10782	NF1_mut	1028	VX-702	p38	4	27	0.693147180559945	NA	3.29270455522341	3.33204546851018	-0.0393409132867704	1.01818089994914	0.923184768212528	0.0421452417278008	0.038638431823594	0.0426143439984851	0.986101147270283	NA	NA	0.520805977184756	0.945543273076812	86.764580099674
a10783	gain_cnaOV95_(MECOM)	1373	Dabrafenib	BRAF	8	24	2.30258509299405	NA	3.6574203294271	3.64258683650267	0.01483349292443	1.7759056058107	2.11879607662716	0.00725730379181768	0.00835263590356117	0.0070009063581253	0.986150201423974	NA	NA	0.748945597017304	0.984747428137388	86.764580099674
a10784	loss_cnaOV55	1032	Afatinib	ERBB2, EGFR	7	24	-0.693147180559945	NA	0.37526194002235	0.351797380953121	0.0234645590692296	2.34799157037926	1.47035924907449	0.0138863260816202	0.00999345967219102	0.0159583850572568	0.986159043441981	NA	NA	0.838261397938582	0.980677684483385	86.764580099674
a10785	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1166	QL-VIII-58	MTOR, ATR	4	19	2.30258509299405	NA	-0.958292310375007	-1.22352978910058	0.265237478725576	1.33066587985892	1.34198754555553	0.197882888709654	0.199326880428991	0.197645261019005	0.986221672781799	NA	NA	0.0512056520189027	0.734259431100621	86.764580099674
a10786	PIK3R1_mut	1494	SN-38	TOP1	5	27	-2.99573227355399	NA	-4.43839353280108	-4.13623193560025	-0.30216159720083	0.917918217202926	1.39990946331668	0.224545939227512	0.329181392784179	0.215843670693494	0.986524451830787	NA	NA	0.22057472229965	0.555484421448314	86.7680062883428
a10787	loss_cnaOV55	194	AUY922	HSP90	4	15	-1.36257783450257	NA	-2.37654522841345	-2.59068398893507	0.214138760521626	1.53161170522657	2.11703432779461	0.105692544736892	0.139812695209161	0.101150348726136	0.986526754638674	NA	NA	0.350534228171499	0.826978591304524	86.7680062883428
a10788	gain_cnaOV72_(ASXL1)	1072	BMS-708163	g-secretase	5	28	1.6094379124341	NA	3.84955938775844	3.83991484321981	0.00964454453862507	0.827043173226117	0.8781066926573	0.0110642422274776	0.0116614765115632	0.0109833402014498	0.986574811225643	NA	NA	0.924208982652386	0.981824969179082	86.7680062883428
a10789	gain_cnaOV4_(KRAS)	1129	PF-4708671	RPS6KB1 (p70S6KA)	6	26	2.30258509299405	NA	4.31919267888897	4.16883991433674	0.150352764552228	1.20038555650861	0.929637162914189	0.153425824423343	0.125253726802193	0.161732738911715	0.986681030002707	NA	NA	0.0494742279486819	0.78269957906627	86.7680062883428
a10790	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1054	PD-0332991	CDK4, CDK6	3	30	1.38629436111989	0.693147180559945	2.51165168246542	2.26140730448827	0.250244377977142	2.88105143730588	1.70444936106474	0.138741633433247	0.0868586984379391	0.146818311939065	0.986724972139935	NA	NA	0.112646991519127	0.895196690570058	86.7680062883428
a10791	gain_cnaOV19	301	PHA-793887	CDK-pan	3	29	2.32630161961136	NA	3.04335055219611	3.00637284469196	0.0369777075041524	0.711824639302094	1.68276335094257	0.0226016805492401	0.0519477768294268	0.0219743955580207	0.98697237858494	NA	NA	0.665444675949249	0.945752301834144	86.7680062883428
a10792	loss_cnaOV54	204	Tipifarnib	Farnesyl-transferase (FNTA)	6	13	2.77258872223978	NA	1.74209413246551	1.91549150461623	-0.173397372150719	1.07968098341476	1.88159964644897	0.10285666618415	0.160600561475396	0.0921542329570277	0.987030159078162	NA	NA	0.351304901292461	0.802881559874906	86.7680062883428
a10793	loss_cnaOV44	308	XL-880	MET	3	29	1.63315443905142	NA	0.202289916491677	0.258354450799817	-0.0560645343081402	0.401805320271561	1.00766872506276	0.0572663872223384	0.139531587760582	0.0556378628349791	0.987037353898088	NA	NA	0.371282301624475	0.857797007505675	86.7680062883428
a10794	gain_cnaOV51_(MYC)	1239	YK 4-279	RNA helicase A	7	17	2.30258509299405	NA	1.68483658958701	1.52202138260551	0.162815206981507	0.772358588403644	1.15519839134734	0.152945536034961	0.210802610893501	0.140941338042906	0.987083643972548	NA	NA	0.291119325280761	0.692471785299322	86.7680062883428
a10795	gain_cnaOV19	221	TAK-715	p38a	3	29	2.99573227355399	2.32630161961136	4.30928087362334	4.27469811381824	0.0345827598051009	1.21728831379937	0.876438064518383	0.0382903248543629	0.0284096704232394	0.03945830424892	0.987357247897457	NA	NA	0.524164284947891	0.96573477530473	86.7840169792056
a10796	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.81472399085819	4.79303759928833	0.0216863915698644	1.21718810734677	0.612109767727411	0.0323832765962499	0.0178167954804755	0.0354289258450813	0.98751735953728	NA	NA	0.763550309792571	0.9783398586466	86.7846254631809
a10797	loss_cnaOV43_(NF1)	229	LY317615	PRKCB (PKCbeta)	5	27	2.99573227355399	2.32630161961136	2.85171251430183	2.73000140271555	0.121711111586274	1.36506989642064	1.73819905454258	0.0718820454528729	0.0891610839162253	0.0700213886713356	0.98759173902287	NA	NA	0.324323988692271	0.866391997625858	86.7846254631809
a10798	loss_cnaOV55	309	Y-39983	ROCK	7	25	2.99573227355399	NA	5.03329217881591	4.94496887307448	0.0883233057414285	1.58125502232033	1.14823870808556	0.0708325919697264	0.0558564586323484	0.076920683059613	0.987939668236118	NA	NA	0.375578633740562	0.893749257109142	86.7846254631809
a10799	loss_cnaOV82	1016	Temsirolimus	MTOR	3	28	-1.6094379124341	NA	-1.76436304823426	-2.0577502597829	0.293387211548644	0.836956808920925	1.61246434659064	0.186714168645878	0.350540444168085	0.181949580571488	0.988055289806477	NA	NA	0.0390214916900654	0.635537631023044	86.7846254631809
a10800	loss_cnaOV38	1203	QL-XII-61	BTK	7	16	2.30258509299405	NA	4.10509957173392	3.79813030045698	0.306969271276938	1.31162096737234	1.5877159305369	0.202756740432708	0.234038094017291	0.193340172113241	0.988252672842271	NA	NA	0.0720411313718538	0.63637665954454	86.7846254631809
a10801	loss_cnaOV84	277	ABT-869	VEGFR and PDGFR family	6	26	0.0237165266173161	NA	2.77030531048432	2.7035121485312	0.0667931619531243	0.858913230351266	0.497127843563068	0.116465877146147	0.077764737569368	0.134358118978807	0.988356548334183	NA	NA	0.137996199975952	0.860639348549724	86.7846254631809
a10802	BRCA1_mut	1527	GDC0941 (rescreen)	PI3K	3	28	1.38629436111989	NA	0.38381279942923	0.382117164512022	0.00169563491720781	0.836007205073161	0.924783377336922	0.0018452149260019	0.00202825395154271	0.00183354822195301	0.988451366727105	NA	NA	0.910242477989607	0.99760489591078	86.7846254631809
a10803	SMARCA4_mut	252	WZ3105	CLK2, CNSK1E, FLT3, ULK1	3	29	0.246860077931526	2.32630161961136	1.03872526601095	1.00060386710467	0.0381213989062807	2.41407564464015	1.48252209561189	0.0244054030615079	0.0157913025596028	0.0257138824568727	0.988500580809875	NA	NA	0.79229494442529	0.980869307196395	86.7846254631809
a10804	loss_cnaOV35	199	Pazopanib	VEGFR, PDGFRA, PDGFRB, KIT	3	16	2.07944154167984	NA	3.49924233829556	3.4577873123161	0.041455025979463	1.33094815306106	1.09631277483715	0.0368012672161999	0.0311469878703541	0.0378131377568058	0.989020706317878	NA	NA	0.775558611344355	0.963204430550077	86.7846254631809
a10805	loss_cnaOV55	1239	YK 4-279	RNA helicase A	5	19	2.30258509299405	NA	1.68439075732255	1.53927714972579	0.145113607596759	0.756303657566645	1.12277097749511	0.13618571804648	0.191872148369152	0.129245955324305	0.989032098997048	NA	NA	0.291120162514587	0.740449403223893	86.7846254631809
a10806	loss_cnaOV84	172	Embelin	XIAP	5	14	3.46573590279973	NA	3.06972114997715	3.10807502160262	-0.0383538716254672	1.38314446940199	0.801030888171121	0.0395419146278484	0.0277294761855568	0.0478806400500175	0.989036165520559	NA	NA	0.674461715863231	0.955547341677893	86.7846254631809
a10807	gain_cnaOV94	184	BMS-754807	IGF1R	3	14	0.940007258491471	NA	0.719991915397803	0.821143887716316	-0.101151972318513	0.275273587897639	1.16212990825743	0.093095198192104	0.367459780980244	0.0870401592797713	0.989051178160928	NA	NA	0.361495846264	0.776031467694453	86.7846254631809
a10808	loss_cnaOV38	155	AP-24534	ABL	4	15	-0.669430653942629	NA	0.724047735340968	0.805751668832036	-0.0817039334910679	1.70752669146284	1.16139101950934	0.0640874016853159	0.0478492862803053	0.0703500648089961	0.989070640690496	NA	NA	0.588478656111117	0.932643395795276	86.7846254631809
a10809	loss_cnaOV41	1028	VX-702	p38	4	27	0.693147180559945	NA	3.38126145988521	3.3189259270788	0.0623355328064075	1.65831646497393	0.80886706701146	0.0667897464221887	0.0375896483711193	0.0770652377240676	0.989070873703205	NA	NA	0.520806848527452	0.945459470226158	86.7846254631809
a10810	loss_cnaOV42	1028	VX-702	p38	4	27	0.693147180559945	NA	3.38126145988521	3.3189259270788	0.0623355328064075	1.65831646497393	0.80886706701146	0.0667897464221887	0.0375896483711193	0.0770652377240676	0.989070873703205	NA	NA	0.520806848527452	0.945459470226158	86.7846254631809
a10811	loss_cnaOV54	159	HG-6-64-1	BRAFV600E, TAK, MAP4K5	6	13	1.63315443905142	NA	1.26510316684771	1.13656510241231	0.128538064435402	0.493689946756994	1.8785314117496	0.0802945929316661	0.260361924077566	0.0684247618280104	0.989170460443916	NA	NA	0.539155793071961	0.821117586223673	86.7846254631809
a10812	loss_cnaOV34	1015	CI-1040	MAP2K1 (MEK1), MAP2K2 (MEK2)	5	26	2.30258509299405	NA	2.13152925726075	2.17354301840009	-0.042013761139335	1.03487877423198	1.3522073552769	0.0319981624935489	0.0405977609991226	0.0310705018541566	0.989252936534048	NA	NA	0.688468738815588	0.939442826257535	86.7846254631809
a10813	gain_cnaOV50	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	4	27	3.68887945411394	NA	3.46905566355134	3.4926560781561	-0.0236004146047577	0.817303555268041	1.15346899715642	0.0210086228306442	0.0288759475627361	0.0204603805242607	0.989344350984104	NA	NA	0.728512250978353	0.961498344809767	86.7846254631809
a10814	gain_cnaOV49	1091	BMS-536924	IGF1R	3	29	1.38629436111989	NA	2.36154389984027	2.3968426227906	-0.0352987229503277	0.857273650142897	0.956610945635356	0.0371443683923419	0.0411755603877989	0.0368997690350314	0.989382451328062	NA	NA	0.736413895258352	0.951396110581341	86.7846254631809
a10815	loss_cnaOV59	263	FR-180204	ERK	4	28	2.99573227355399	NA	4.801153900337	4.81328114148234	-0.0121272411453468	0.620386836715878	0.766758880106196	0.0160966309804918	0.019547869857369	0.0158162382725417	0.989497330772271	NA	NA	0.766647661322661	0.973283668148353	86.7846254631809
a10816	loss_cnaOV43_(NF1)	171	AKT inhibitor VIII	AKT1, AKT2, AKT3	3	16	0.940007258491471	NA	2.32567995132567	2.41275135594174	-0.0870714046160677	1.46343517110392	0.918391224360583	0.0872385454250857	0.0594979581845	0.0948086200156038	0.989535322436144	NA	NA	0.415423953271221	0.928772964848691	86.7846254631809
a10817	loss_cnaOV84	346	THZ-2-102-1	CDK7	6	26	0.916290731874155	2.99573227355399	-1.15336515792944	-1.03773815586619	-0.115627002063251	1.74012211010025	2.03514204595628	0.0581328484652571	0.0664476368595702	0.0568151998495611	0.989789892434673	NA	NA	0.446444141929089	0.890469960132532	86.7846254631809
a10818	gain_cnaOV95_(MECOM)	1495	AZD-2281	PARP1, PARP2	8	25	2.30258509299405	NA	3.58227144020608	3.55450512218806	0.0277663180180214	0.756260239432566	0.968103691190804	0.0300331993462237	0.0367152953047683	0.0286811405334772	0.989834976893131	NA	NA	0.145275010398063	0.934077443870196	86.7846254631809
a10819	ARID1A_mut	1091	BMS-536924	IGF1R	9	23	1.38629436111989	NA	2.45980352892964	2.36760156522093	0.0922019637087144	0.658107739592336	1.03520554161832	0.097115412204748	0.140101624949478	0.0890663351401465	0.989877356436849	NA	NA	0.736413966899065	0.767167429717009	86.7846254631809
a10820	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.38629436111989	NA	1.20292543926382	1.22026223113674	-0.0173367918729213	1.37601390725678	1.20911828725085	0.0138832543135466	0.01259928535714	0.0143383753729667	0.989936018755277	NA	NA	0.269820750395448	0.975130525445392	86.7846254631809
a10821	loss_cnaOV54	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	10	21	3.68887945411394	NA	3.46559393502809	3.50104749591139	-0.0354535608833069	0.664126043249206	1.27711724586139	0.031562894659818	0.053383783460519	0.0277606155567918	0.989966087532203	NA	NA	0.728512346561806	0.919784327844096	86.7846254631809
a10822	loss_cnaOV61, loss_cnaOV62, loss_cnaOV63	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	3.92985703309246	4.04332778183248	-0.113470748740024	1.63884473963788	1.49990681297002	0.0751677344699267	0.0692382542382241	0.0756518656751321	0.990024985802842	NA	NA	0.332755310296977	0.917469908288294	86.7846254631809
a10823	gain_cnaOV94	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	7	26	-1.38629436111989	0.693147180559945	-2.1683985677581	-2.11150819466218	-0.0568903730959187	1.33918054536888	1.29488598394851	0.0436417571334399	0.0424814811510333	0.0439346581870029	0.990383275215776	NA	NA	0.609730570122729	0.922120201292927	86.7846254631809
a10824	loss_cnaOV42	226	GSK1070916	AURKB	4	28	0.940007258491471	2.32630161961136	2.29985733849726	2.3159859590579	-0.016128620560635	0.844214468303752	1.50890448286792	0.0110761809023048	0.0191048852704949	0.0106889605960875	0.990385378424361	NA	NA	0.822054866619159	0.975733392795554	86.7846254631809
a10825	loss_cnaOV39	204	Tipifarnib	Farnesyl-transferase (FNTA)	5	14	2.77258872223978	NA	1.74064986212695	1.90362178886924	-0.162971926742286	2.14416155670855	1.51782805829242	0.096646870325198	0.0760072981592208	0.107371797386347	0.99044869546473	NA	NA	0.351306728224206	0.881197719589518	86.7846254631809
a10826	loss_cnaOV34	263	FR-180204	ERK	5	27	2.99573227355399	NA	4.79270868704946	4.81529422694838	-0.0225855398989196	0.767436304247315	0.751178206753608	0.0299794962159437	0.0294298559684	0.030066819958114	0.990453573044796	NA	NA	0.766647780843484	0.953776550643388	86.7846254631809
a10827	loss_cnaOV33_(ZFHX3)	1061	SB590885	BRAF	4	29	1.6094379124341	NA	3.88032515759536	3.9340521920715	-0.05372703447614	1.64988099725783	1.24967156155246	0.0415257924384215	0.0325641876992563	0.0429929240042841	0.990491145873299	NA	NA	0.575473871911614	0.953430746010294	86.7846254631809
a10828	ARID1A_mut	226	GSK1070916	AURKB	8	24	0.940007258491471	2.32630161961136	2.37722265981582	2.29288562204515	0.0843370377706689	0.883441529326574	1.58945505619656	0.0579367032882676	0.0954641987851273	0.0530603475964149	0.990617549931271	NA	NA	0.822054887865399	0.853142515097514	86.7846254631809
a10829	ARID1A_mut	1377	Afatinib (rescreen)	ERBB2, EGFR	9	24	2.30258509299405	NA	2.81948596638813	2.59346889440411	0.226017071984016	0.920219966119328	1.9141435600858	0.131884451266953	0.245612006156697	0.118077388079442	0.990685783380941	NA	NA	0.642075963562855	0.652531552965932	86.7846254631809
a10830	gain_cnaOV26	170	Shikonin	unknown	3	15	2.77258872223978	NA	-0.054109421616822	-0.0027153568254262	-0.0513940647913958	0.717925590461309	0.814076448555909	0.064027472366831	0.071586896294325	0.0631317425808888	0.990756671463087	NA	NA	0.588773401406988	0.918654658369128	86.7846254631809
a10831	gain_cnaOV26	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.48947359857285	2.32935212080976	0.160121477763088	2.05662455570768	1.52527029950726	0.102313727140761	0.0778564455620783	0.104979083258106	0.990800514640494	NA	NA	0.244980105554041	0.906468863863085	86.7846254631809
a10832	loss_cnaOV39	281	CH5424802	ALK	9	23	1.63315443905142	NA	3.92800946849963	3.92744764164554	0.000561826854088565	0.692105427149972	0.750838540665261	0.000763730430415881	0.000811764843980661	0.000748265870303851	0.990859299191791	NA	NA	0.956067807429635	0.998417343152168	86.7846254631809
a10833	loss_cnaOV21, loss_cnaOV22	1036	PLX4720	BRAF	3	30	2.30258509299405	NA	4.40411313674991	4.2982683360977	0.105844800652202	0.653763276617246	1.35416870526978	0.0801707427230835	0.161900804829345	0.0781621966600646	0.990928253408949	NA	NA	0.373981013709725	0.825964959102411	86.7846254631809
a10834	MLL2_mut	1236	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	29	2.99573227355399	NA	4.6503083452081	3.96879833575156	0.681510009456541	2.08228121679139	1.44499471909753	0.45556980545911	0.32729009125227	0.471634948176266	0.990931303906403	NA	NA	0.332755536503555	0.631096501076624	86.7846254631809
a10835	loss_cnaOV39	178	BAY 61-3606	SYK	5	14	2.07944154167984	NA	2.69505180232174	2.71394381912293	-0.0188920168011886	2.02473221045821	1.05968910335311	0.0139909495383821	0.00933062491109042	0.0178278862558931	0.991287666768281	NA	NA	0.941803565108529	0.984913044768142	86.7970464370684
a10836	loss_cnaOV70	290	KIN001-260	IKK	3	28	2.99573227355399	NA	4.87249002125746	4.84786317833267	0.0246268429247927	1.11528177005112	0.89238347745544	0.0270770077887974	0.0220812745138512	0.0275967042722644	0.991413339169538	NA	NA	0.66741237433493	0.973472333298525	86.7970464370684
a10837	loss_cnaOV84	136	Mitomycin C	DNA crosslinker	5	14	2.77258872223978	NA	-0.535086353032214	-0.562619565429168	0.0275332123969535	1.2948002377967	1.56774362406851	0.0182584281779239	0.0212644480540145	0.0175623182095941	0.991545727087606	NA	NA	0.910236647846293	0.970154771410558	86.7970464370684
a10838	PTEN_mut	1248	FK866	NAMPT	4	28	0	NA	-3.28846070969063	-1.48262875488682	-1.80583195480382	2.15156890805367	2.76642359901471	0.666058779983529	0.839309374682028	0.652767694523349	0.991562070300543	NA	NA	0.045848236249996	0.197037526082695	86.7970464370684
a10839	loss_cnaOV16, loss_cnaOV17	1498	AZD6244	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	1.38629436111989	NA	1.118009144589	1.23784831203686	-0.119839167447862	1.57140932795938	1.1754834090436	0.0960351137325275	0.0762622222711915	0.101948837836312	0.991579874039189	NA	NA	0.269821129966655	0.865685255563627	86.7970464370684
a10840	PIK3CA_mut	1373	Dabrafenib	BRAF	6	26	2.30258509299405	NA	3.51868714364159	3.67574322498582	-0.157056081344235	1.22799594211892	2.16953370163983	0.0768763554349331	0.127896254342041	0.0723916301579115	0.991621998350458	NA	NA	0.748946408681889	0.81483216538837	86.7970464370684
a10841	gain_cnaOV95_(MECOM)	1031	Elesclomol	HSP70	8	23	-1.6094379124341	NA	-4.05957767485248	-4.05984084399997	0.000263169147490139	1.38047906780531	1.5841836211804	0.00017116841539576	0.000190636101356123	0.000166122881193562	0.991764199577552	NA	NA	0.864966770523479	0.999650032669873	86.8014858468093
a10842	gain_cnaOV19	291	KIN001-266	MAP3K8 (COT)	3	29	2.99573227355399	NA	3.31334166909352	3.30131355671293	0.0120281123805919	0.384144458621194	1.15071952123566	0.0107767528579024	0.0313114301420988	0.0104526882169131	0.992052306426932	NA	NA	0.951235794753684	0.969936025759603	86.8097496473817
a10843	loss_cnaOV41	224	AS605240	PI3Kgamma	5	27	2.99573227355399	2.32630161961136	3.32680872384857	3.38404409888419	-0.0572353750356114	1.05309931396829	1.75938819798852	0.0340193548838793	0.054349456197001	0.0325314078502104	0.992164364716625	NA	NA	0.631923102324791	0.923597950654004	86.8097496473817
a10844	loss_cnaOV70	277	ABT-869	VEGFR and PDGFR family	3	29	0.0237165266173161	NA	2.77030768199468	2.71042154064597	0.0598861413487075	0.289942626235529	0.588913258596922	0.104358813788497	0.206544798625298	0.10168923941598	0.99228258259255	NA	NA	0.137996994136007	0.779408830365613	86.8097496473817
a10845	gain_cnaOV18_(CCNE1)	1149	TW 37	BCL2, BCL2L1	4	29	1.6094379124341	NA	-0.599211278843806	-0.759865680220718	0.160654401376912	0.58343545193561	0.959267587093426	0.172828127772947	0.275359340684431	0.167476107332777	0.992305197962891	NA	NA	0.0431237783910047	0.656171308766346	86.8097496473817
a10846	gain_cnaOV4_(KRAS)	1378	Bleomycin (50 uM)	DNA damage	7	25	3.91202300542815	NA	2.00676573888452	2.0517413658266	-0.0449756269420778	1.59203303720408	2.09442665517625	0.0224423792800234	0.0282504356951434	0.0214739565269202	0.99231607610913	NA	NA	0.134812168303446	0.952056217071641	86.8097496473817
a10847	gain_cnaOV4_(KRAS)	135	Gemcitabine	DNA replication	6	13	0.0237165266173161	NA	-2.0780933261265	-2.21591284235193	0.137819516225428	1.08715624333389	3.12963225316219	0.0511444982557045	0.126770661595787	0.0440369682687718	0.992564511922146	NA	NA	0.42212240845921	0.889300070704699	86.8157270006109
a10848	gain_cnaOV72_(ASXL1)	281	CH5424802	ALK	5	27	1.63315443905142	NA	3.92881305880256	3.92738206223449	0.00143099656806767	0.452664960652785	0.769993452172028	0.00194525384280411	0.00316127090111865	0.00185845290506179	0.992567398273191	NA	NA	0.956067841663206	0.995572881743612	86.8157270006109
a10849	loss_cnaOV102	245	UNC0638	G9a(EHMT2), GLP(EHMT1)	3	28	3.68887945411394	NA	3.46728030012561	3.49200342371583	-0.0247231235902268	0.773129855593815	1.14506249013842	0.0220079507352217	0.0319779703388091	0.0215910693111937	0.993226976332502	NA	NA	0.728512753786228	0.963346329221809	86.8464862417745
a10850	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.32893016800552	3.23605166419229	0.0928785038132363	1.65218362626189	0.944845085959345	0.0891211177829439	0.0562156060239965	0.098300245398358	0.993479131856456	NA	NA	0.569446336915205	0.932324512437555	86.8464862417745
a10851	loss_cnaOV56	1013	Nilotinib	ABL	3	18	0.693147180559945	NA	3.32893016800552	3.23605166419229	0.0928785038132363	1.65218362626189	0.944845085959345	0.0891211177829439	0.0562156060239965	0.098300245398358	0.993479131856456	NA	NA	0.569446336915205	0.932324512437555	86.8464862417745
a10852	gain_cnaOV4_(KRAS)	202	GSK-1904529A	IGF1R	6	13	0.0237165266173161	NA	2.47807379824686	2.49867567170075	-0.0206018734538915	0.532056906304024	0.865754595280651	0.0263275282601186	0.0387211841624313	0.0237964355790835	0.99348196450146	NA	NA	0.752040381289	0.950094563494472	86.8464862417745
a10853	loss_cnaOV81_(RB1)	196	Phenformin	AAPK1 (AMPK) agonist	4	27	8.29404964010203	NA	8.75218558701025	8.75829719816099	-0.00611161115073422	1.72478501997961	1.72332771845292	0.00354609067712045	0.0035434045866229	0.00354640100387915	0.99354307611633	NA	NA	0.922304241395629	0.995043494794796	86.8464862417745
a10854	gain_cnaOV4_(KRAS)	152	CP466722	ATM	8	24	2.77258872223978	NA	2.64898605247403	2.64622689585963	0.00275915661439807	0.906038659001489	0.7927772264157	0.00336234711607949	0.00304529678395714	0.00348036815698246	0.993555972216222	NA	NA	0.558403559802195	0.994005854647507	86.8464862417745
a10855	gain_cnaOV95_(MECOM)	235	QL-XII-47	BTK, BMX	9	23	2.32630161961136	NA	1.58284343494084	1.55841966813402	0.0244237668068161	1.36186437297386	1.72313916106093	0.0149415089158131	0.017934066924361	0.0141739955534285	0.993559780859853	NA	NA	0.0806336981684539	0.9668010738877	86.8464862417745
a10856	gain_cnaOV72_(ASXL1)	153	Midostaurin	KIT	4	15	-0.669430653942629	NA	0.0986314365799779	0.124063346195383	-0.0254319096154053	0.414680035481773	1.47347682023694	0.0188599965768687	0.0613289945002022	0.0172597961950401	0.993898737114606	NA	NA	0.871362023011276	0.953891454535866	86.8571144237277
a10857	loss_cnaOV85	346	THZ-2-102-1	CDK7	7	25	0.916290731874155	2.99573227355399	-1.16767874013649	-1.02910527276569	-0.138573467370803	1.58895823801812	2.07662222074464	0.0696811518486041	0.0872102639674429	0.0667302246824234	0.994019295828195	NA	NA	0.446444991144788	0.852554524167443	86.8571144237277
a10858	MLL2_mut	1009	ATRA	Retinoic acid and retinoid X receptor agonist	3	28	2.30258509299405	NA	4.75820217834825	4.48525007757193	0.272952100776316	0.906799870240188	0.927375251732438	0.294773938981523	0.30100588865768	0.294327566178213	0.994177483080563	NA	NA	0.531109773038029	0.661564311986955	86.8571144237277
a10859	loss_cnaOV16, loss_cnaOV17	272	AR-42	HDAC	6	24	1.63315443905142	NA	0.195985628084141	0.319875811634325	-0.123890183550184	1.4628783099683	1.93434617353906	0.0666453892123716	0.0846893297316502	0.0640475759948986	0.994313298533491	NA	NA	0.488999900997042	0.866097714190482	86.8571144237277
a10860	loss_cnaOV52, loss_cnaOV53	302	PI-103	PI3Ka, PRKDC (DNAPK)	8	24	2.32630161961136	NA	1.42908773930538	1.24349457735747	0.185593161947919	2.51659689868923	2.29021827117292	0.0791443582170866	0.073747671724695	0.0810373248192054	0.994347222784405	NA	NA	0.366473805435436	0.856819522948369	86.8571144237277
a10861	PIK3CA_mut	260	NG-25	MAP3K7 (TAK1)	6	26	2.32630161961136	NA	3.18767026984664	2.97143822493728	0.216232044909365	1.19043781242706	1.06551629501744	0.19886448002823	0.181640773379428	0.202936403620019	0.994365595985264	NA	NA	0.43741203598329	0.694990175086016	86.8571144237277
a10862	loss_cnaOV35	1011	ABT-263	BCL2, BCL2L1, BCL2L2	5	28	0.693147180559945	NA	1.59002500618289	1.7641747849992	-0.17414977881631	1.77024789420883	1.704982586261	0.10163136696564	0.0983759276799718	0.102141675944162	0.994377492051688	NA	NA	0.232057152457756	0.845992510510734	86.8571144237277
a10863	loss_cnaOV83	170	Shikonin	unknown	3	15	2.77258872223978	NA	-0.0521182176408493	-0.00311359762062074	-0.0490046200202286	0.107965148909362	0.857163411667025	0.0610488915695929	0.4538929507833	0.0571706857213184	0.994413702477213	NA	NA	0.588774484762803	0.833982769895195	86.8571144237277
a10864	loss_cnaOV70	230	GSK429286A	ROCK2	3	29	2.99573227355399	2.32630161961136	5.61090014105638	5.53128155646625	0.0796185845901327	0.731337945251598	1.00409524395612	0.0805647148836437	0.108867022567442	0.0792938569018977	0.994723633454308	NA	NA	0.307198354633568	0.874571508440681	86.8704105270261
a10865	gain_cnaOV96	293	MP470	PDGFR	5	27	2.99573227355399	NA	3.98472811019019	4.06118987890363	-0.076461768713441	1.47272726999977	1.82399925321711	0.0429278308504835	0.051918485025033	0.0419198465013515	0.994749038242059	NA	NA	0.6244042814007	0.92148076652941	86.8704105270261
a10866	loss_cnaOV39	1032	Afatinib	ERBB2, EGFR	10	21	-0.693147180559945	NA	0.382333404322667	0.345077937133556	0.0372554671891113	1.26098182548055	1.85049029776652	0.0220486400952274	0.029544809002234	0.0201327546726819	0.995089975436312	NA	NA	0.838262160193464	0.948179723993458	86.8921867814776
a10867	loss_cnaOV70	1037	BX-795	TBK1, PDPK1, IKK, AURKB, AURKC	3	30	1.6094379124341	NA	2.48463305298309	2.32983617536874	0.154796877614352	2.27536804524197	1.50374724907412	0.0989084586039669	0.068031577545465	0.102940755309553	0.995313680623824	NA	NA	0.244980875149578	0.917938732934418	86.8974718183481
a10868	loss_cnaOV44	274	PXD101, Belinostat	HDAC	3	27	2.99573227355399	NA	0.737723765819447	0.867765991971235	-0.130042226151788	1.72662478985735	2.11965323332707	0.0621014868828321	0.0753158572236946	0.0613507077984022	0.995333667489212	NA	NA	0.419099952545587	0.912259003454775	86.8974718183481
a10869	PIK3CA_mut	154	CHIR-99021	GSK3B	5	14	0.940007258491471	NA	3.0292057288024	3.42324698887388	-0.394041260071479	1.02249479449416	0.958760469162633	0.404504994100592	0.385372387412903	0.410990307532838	0.995468526337304	NA	NA	0.194770617762246	0.477766528584229	86.9012495855266
a10870	PTEN_mut	286	KIN001-236	TIE2	3	29	2.32630161961136	NA	4.73700092570119	4.80107791637353	-0.0640769906723477	0.428679809773358	0.68339151960107	0.0957183468827406	0.149475177536878	0.0937632218640242	0.995709034784428	NA	NA	0.763551177010216	0.831853462874952	86.9072473878929
a10871	gain_cnaOV95_(MECOM)	202	GSK-1904529A	IGF1R	5	14	0.0237165266173161	NA	2.47550105766751	2.49812294523239	-0.022621887564878	0.496950108189079	0.851325409219534	0.0289091414603279	0.0455214461011263	0.0265725506602898	0.995765467324652	NA	NA	0.75204067855998	0.944419783501615	86.9072473878929
a10872	ARID1A_mut	269	NSC-207895	MDM4	8	23	2.99573227355399	NA	3.76856445309061	3.92545808528546	-0.156893632194854	1.36982303879926	1.66984739328813	0.0979007367862637	0.114535693845814	0.0939568686488836	0.995892324017147	NA	NA	0.717378647988767	0.796140661375227	86.9072473878929
a10873	loss_cnaOV33_(ZFHX3)	328	SNX-2112	HSP90	4	28	0.940007258491471	NA	0.701435386179629	0.695393879098887	0.00604150708074225	2.18955496241215	2.34478781408384	0.00259322196632773	0.00275923974709754	0.00257656878138578	0.996038284021696	NA	NA	0.946180870174378	0.996160556551137	86.9072473878929
a10874	loss_cnaOV57_(ZNRF3)	1203	QL-XII-61	BTK	4	19	2.30258509299405	NA	4.11473212130371	3.84457122759128	0.27016089371243	1.72289476284596	1.48037743066766	0.178042245826744	0.15680638164235	0.182494604494602	0.996175011521159	NA	NA	0.0720424347487158	0.785015646588954	86.9072473878929
a10875	gain_cnaOV48_(SOX17)	260	NG-25	MAP3K7 (TAK1)	3	29	2.32630161961136	NA	2.95140119000814	3.01824868611809	-0.0668474961099492	1.33388531116196	1.07114963656328	0.0612922005411225	0.0501148753574008	0.0624072434215869	0.996272546753693	NA	NA	0.437412259076017	0.93984409349001	86.9072473878929
a10876	loss_cnaOV20	275	I-BET	BRD2, BRD3, BRD4	5	26	2.99573227355399	NA	3.88391793560048	3.92676899126299	-0.0428510556625072	0.797108505253737	1.28758828137666	0.0347928791274597	0.0537581212345323	0.0332800913788155	0.996287336938023	NA	NA	0.700627542700691	0.924090346488551	86.9072473878929
a10877	loss_cnaOV20	1164	XMD8-92	MAP2K5 (ERK5)	4	19	2.30258509299405	NA	2.98962930745384	2.90835716977331	0.0812721376805325	0.538715076431252	0.904527780170589	0.0943019986310336	0.150862935225285	0.0898503500524937	0.996311289243315	NA	NA	0.3342847145124	0.817755589560057	86.9072473878929
a10878	loss_cnaOV83	344	THZ-2-49	CDK9	5	27	2.99573227355399	NA	2.72970264630559	2.56085223349741	0.168850412808182	2.29966879164694	2.36085100563084	0.0717661796851603	0.0734237962533975	0.071520994931683	0.996384756072138	NA	NA	0.388943821558563	0.885813537031126	86.9072473878929
a10879	PTEN_mut	1029	AMG-706	VEGFR, RET, c-KIT, PDGFR	4	29	0.693147180559945	NA	2.78408874560212	2.79976657731565	-0.0156778317135235	1.0727106349791	0.958338747745544	0.0161627705502341	0.0146151545461549	0.016359384143034	0.996491936356933	NA	NA	0.966400185244465	0.979300961856094	86.9072473878929
a10880	gain_cnaOV50	152	CP466722	ATM	4	28	2.77258872223978	NA	2.67805796985908	2.64246793003525	0.0355900398238327	0.599242400173074	0.841517196954152	0.043375234426374	0.0593917249739897	0.0422927064980369	0.996544768249675	NA	NA	0.558403878645961	0.920610261091022	86.9072473878929
a10881	loss_cnaOV27, loss_cnaOV28, loss_cnaOV29, loss_cnaOV30	222	BX-912	PDPK1 (PDK1)	5	27	2.32630161961136	NA	3.4935861044803	3.39442294920606	0.0991631552742409	1.4733162251534	1.18919268881658	0.0805634013938278	0.0673060905603724	0.0833869533565015	0.996692984668782	NA	NA	0.329766555337607	0.892484634706756	86.9121848780442
a10882	loss_cnaOV34	225	Genentech Cpd 10	AURKA, AURKB	5	27	2.32630161961136	NA	2.96606308770711	2.8215764744876	0.144486613219507	1.65282541085524	1.89837122328303	0.0773690823009671	0.0874179524773546	0.0761108319845017	0.996894731539443	NA	NA	0.349338806378995	0.866533372387139	86.9171320798965
a10883	loss_cnaOV1	266	Zibotentan, ZD4054	Endothelin A Receptor	3	29	2.99573227355399	NA	5.74264627433754	5.71222105166197	0.0304252226755697	0.455550775884564	0.483648136125651	0.0631456696619232	0.066787774900595	0.062907763729426	0.997146278941745	NA	NA	0.384700538808534	0.921030241992525	86.9171320798965
a10884	gain_cnaOV51_(MYC)	201	Epothilone B	Microtubules	5	14	-3.44201937618241	NA	-4.80818147871657	-4.59906695430902	-0.209114524407547	1.71513326060107	2.18676479330199	0.100274977536481	0.121923193498249	0.0956273509835444	0.997237328054204	NA	NA	0.355176467820292	0.833130694283113	86.9171320798965
a10885	ARID1A_mut	1526	RDEA119 (rescreen)	MAP2K1 (MEK1), MAP2K2 (MEK2)	9	22	1.6094379124341	NA	1.48637835568549	1.27997387286953	0.206404482815955	0.594171268897844	1.55554695770702	0.15176776288999	0.347382133099139	0.132689329494887	0.997268822565389	NA	NA	0.583313874448875	0.597185780837024	86.9171320798965
a10886	loss_cnaOV40	302	PI-103	PI3Ka, PRKDC (DNAPK)	7	25	2.32630161961136	NA	1.43147547786681	1.25024973703818	0.181225740828625	2.01905529494289	2.41986283846141	0.077275577420035	0.0897576907787222	0.0748909144552391	0.997292379822302	NA	NA	0.366474125999839	0.844605049995459	86.9171320798965
a10887	loss_cnaOV36	1017	Olaparib	PARP1, PARP2	3	28	1.6094379124341	NA	4.12729268503681	3.95274487007265	0.174547814964154	1.77070032786449	1.11953117586138	0.148415934126575	0.0985755817725873	0.155911526831626	0.997299345907847	NA	NA	0.0847834897742341	0.881487376591608	86.9171320798965
a10888	loss_cnaOV52, loss_cnaOV53	1373	Dabrafenib	BRAF	9	23	2.30258509299405	NA	3.68937728492714	3.62943700639724	0.059940278529893	2.9293084817687	1.60485067777138	0.0293284164508698	0.0204622623062565	0.0373494427613234	0.997619321510134	NA	NA	0.748946839231565	0.954842769203655	86.9327806469773
a10889	loss_cnaOV35	165	DMOG	Prolyl-4-Hydroxylase	3	16	8.29404964010203	NA	6.58168087948665	6.71938443235048	-0.137703552863835	0.254336292237264	1.63084820733101	0.0897444080146209	0.541423135693802	0.0844367686979253	0.997662141955128	NA	NA	0.342412594664883	0.754532799928341	86.9327806469773
a10890	gain_cnaOV26	1248	FK866	NAMPT	3	29	0	NA	-1.29333141278822	-1.7512915081803	0.457960095392083	2.20035870229742	2.81375246346495	0.164907187659942	0.208129744897467	0.162757776790406	0.998064620822638	NA	NA	0.0458486127306725	0.762791552908918	86.9506707411992
a10891	gain_cnaOV26	200	LAQ824	HDAC	3	16	0.0237165266173161	NA	-2.83383858646959	-2.73103259420471	-0.102805992264879	0.732188461983239	1.29579311439443	0.0827196686890176	0.140409194630593	0.0793382763983306	0.99822893593543	NA	NA	0.384265997796235	0.854805897389718	86.9506707411992
a10892	loss_cnaOV1	1008	Methotrexate	Dihydrofolate reductase (DHFR)	3	28	-1.6094379124341	NA	0.644028267406792	0.557314499392239	0.0867137680145529	1.60718582633494	1.18895626166239	0.0709371790086192	0.0539537909018876	0.0729326812184917	0.998375486865646	NA	NA	0.433909794030878	0.935109221293107	86.9506707411992
a10893	loss_cnaOV81_(RB1)	221	TAK-715	p38a	4	28	2.99573227355399	2.32630161961136	4.31806623036966	4.27220796429002	0.0458582660796445	0.289323743662692	0.947049436743091	0.0507789241845015	0.158501564714676	0.0484222515746922	0.998441762152912	NA	NA	0.524166071910251	0.844683492453159	86.9506707411992
a10894	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1014	RDEA119	MAP2K1 (MEK1), MAP2K2 (MEK2)	8	25	1.6094379124341	NA	1.16230524225349	1.16965584706432	-0.0073506048108376	1.80299290319584	1.40610202710654	0.00488444771435127	0.0040768905955251	0.00522764683439336	0.998477920962456	NA	NA	0.814196983700673	0.991792331864673	86.9506707411992
a10895	loss_cnaOV54	1203	QL-XII-61	BTK	6	17	2.30258509299405	NA	4.11255588849851	3.81355567520341	0.299000213295099	1.142186235902	1.61388823460993	0.197365229213172	0.261778862235172	0.185266988681757	0.998491190418507	NA	NA	0.0720425652587312	0.631795909049518	86.9506707411992
a10896	gain_cnaOV95_(MECOM)	309	Y-39983	ROCK	9	23	2.99573227355399	NA	4.97199266419752	4.96127535220851	0.0107173119890112	1.50058022253628	1.14163054295174	0.00859109724960555	0.00714211198312125	0.00938772359865304	0.998528074548166	NA	NA	0.375580493190547	0.984887119985427	86.9506707411992
a10897	gain_cnaOV72_(ASXL1)	292	Masitinib	KIT	5	27	2.99573227355399	NA	3.9441631368095	4.02636436178049	-0.0822012249709898	0.816836840766257	1.09077541906609	0.0776688622997075	0.100633591518569	0.0753603569847307	0.998672398215959	NA	NA	0.106804106206313	0.850883918482822	86.9506707411992
a10898	loss_cnaOV64_(ARID1B,MAP3K4,MLLT4)	1053	MK-2206	AKT1, AKT2	8	24	1.38629436111989	0.693147180559945	1.34012526151164	1.29981368529345	0.0403115762181911	1.45872620279054	1.14830768446436	0.0328329328951215	0.0276347789880481	0.0351052046098559	0.998706827425947	NA	NA	0.0995452140993427	0.944666445421238	86.9506707411992
a10899	gain_cnaOV50	1129	PF-4708671	RPS6KB1 (p70S6KA)	4	28	2.30258509299405	NA	4.32429246811738	4.17885085620069	0.145441611916684	1.08017200859	0.968888475214122	0.148321222757618	0.134646714375182	0.150111819510024	0.998925374004161	NA	NA	0.0494752619618987	0.812154926807329	86.9506707411992
a10900	loss_cnaOV16, loss_cnaOV17	266	Zibotentan, ZD4054	Endothelin A Receptor	6	26	2.99573227355399	NA	5.74381377188229	5.70844102653523	0.0353727453470647	0.525540787210148	0.472446354679543	0.0734328386424621	0.0673073264871451	0.0748714536511934	0.999025945558775	NA	NA	0.384700631810562	0.883968971625829	86.9506707411992
a10901	loss_cnaOV20	152	CP466722	ATM	5	27	2.77258872223978	NA	2.68014017294482	2.64076418724812	0.0393759856966982	0.781136319275011	0.826357926977803	0.0479918467272715	0.0504085967136234	0.0476500368801519	0.999048003317936	NA	NA	0.558403997533611	0.921750325256448	86.9506707411992
a10902	loss_cnaOV43_(NF1)	254	AC220	FLT3	5	27	0.0237165266173161	NA	2.50340474706702	2.51219256388631	-0.00878781681929075	0.38270355054489	0.664931710729525	0.0138479066967852	0.0229624648289224	0.0132161193059198	0.999058772506342	NA	NA	0.858992289934421	0.968070017708732	86.9506707411992
a10903	RB1_mut	1004	Vinblastine	Microtubules	3	28	-2.30258509299405	NA	-3.54428995923434	-3.2906414102674	-0.253648548966938	0.973996529891464	1.88489281655557	0.138105118410492	0.260420382601571	0.134569216211695	0.999409012911256	NA	NA	0.141968136373735	0.723107513296307	86.9660828311483
a10904	gain_cnaOV94	235	QL-XII-47	BTK, BMX	7	25	2.32630161961136	NA	1.75617693444867	1.51184018961638	0.244336744832288	1.37162923631101	1.6900339793097	0.149777416576561	0.178136145223494	0.144575048681618	0.999578660470192	NA	NA	0.0806340252391248	0.700115437334145	86.9660828311483
a10905	gain_cnaOV50	1066	AZD6482	PI3Kbeta	4	29	1.6094379124341	NA	2.53391606999935	2.35776158742987	0.176154482569476	0.651585644403209	1.36851996172321	0.13382375341751	0.270347396512729	0.128718971952493	0.999619862370349	NA	NA	0.112134475774248	0.681890671631479	86.9660828311483
a10906	loss_cnaOV38	201	Epothilone B	Microtubules	4	15	-3.44201937618241	NA	-4.81059608524101	-4.61236402752967	-0.198232057711343	3.74373977609848	1.51001899740407	0.0950328112327331	0.0529502768800694	0.131277856803213	0.999698106729864	NA	NA	0.35517664662723	0.923472513502175	86.9660828311483
a10907	loss_cnaOV38	1042	BIRB 0796	p38, JNK2	8	25	2.30258509299405	NA	4.38672543740979	4.40094596534829	-0.0142205279385079	1.19920385374907	0.743430449661351	0.0163918657994488	0.0118583074045754	0.0191282559720088	0.999713355237622	NA	NA	0.870310713487347	0.975457819179999	86.9660828311483
a10908	loss_cnaOV1	1021	Axitinib	PDGFR, KIT, VEGFR	3	27	0.693147180559945	NA	2.63646012756701	2.51292616349964	0.12353396406737	1.11599048396375	1.04150989307631	0.117987866616914	0.110694460071564	0.11861045669234	0.999864040458895	NA	NA	0.198643710545212	0.869049327901109	86.9660828311483
a10909	loss_cnaOV16, loss_cnaOV17	1060	PD-0325901	MAP2K1 (MEK1), MAP2K2 (MEK2)	6	27	-1.38629436111989	0.693147180559945	-2.17361638232581	-2.1124557311692	-0.0611606511566078	1.47480225485939	1.26799278583628	0.046917802439232	0.0414704079513623	0.0482342264402321	0.999947656691266	NA	NA	0.609731446468368	0.927731910770293	86.9660828311483
a10910	loss_cnaOV85	175	PAC-1	CASP3 agonist	5	13	0.940007258491471	NA	2.15590072063239	2.13351535114242	0.0223853694899767	1.52465789397424	1.32739067876616	0.0162288686735736	0.0146822245032464	0.0168641906622279	0.999969106207626	NA	NA	0.893560709506121	0.977821800499335	86.9660828311483